Annotation Detail for HNRNPD
Basic Information
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| Gene Symbol: | HNRNPD ( AUF1,AUF1A,HNRPD,P37,hnRNPD0 ) |
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| Gene Full Name: | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
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| Band: | 4q21.22 |
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| Quick Links | Entrez ID:3184; OMIM: 601324; Uniprot ID:HNRPD_HUMAN; ENSEMBL ID: ENSG00000138668; HGNC ID: 5036 |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Pathway ID | Pathway Name |
|---|
| mRNA Processing |
| Gene Expression |
| Pathway ID | Pathway Name |
|---|
| 500866 | mRNA Splicing - Major Pathway |
| 500655 | Processing of Capped Intron-Containing Pre-mRNA |
| Desease ID | Desease Name |
|---|
| 1770 | Melanoma |
| 1807 | Autoimmune disease |
| 1977 | Rheumatism |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D001564 |
Benzo(a)pyrene |
Benzo(a)pyrene results in decreased expression of HNRNPD mRNA | decreases expression | 20064835
|
| D001564 |
Benzo(a)pyrene |
Benzo(a)pyrene results in decreased expression of HNRNPD protein | decreases expression | 20097212
|
| D015123 |
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of HNRNPD mRNA | increases expression | 20382639
|
| D010269 |
Paraquat |
Paraquat results in increased expression of HNRNPD mRNA alternative form | increases expression | 17064354
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000230 |
Adenocarcinoma |
|
Benzo(a)pyrene |
2.06 | 20127859 20464547 |
| MESH:D000236 |
Adenoma |
|
Benzo(a)pyrene |
2.88 | 6695378 |
| MESH:D000382 |
Agricultural Workers' Diseases |
|
Paraquat |
4.50 | 11874814 |
| MESH:D017544 |
Aortic Aneurysm, Abdominal |
|
Benzo(a)pyrene |
4.73 | 19183758 |
| MESH:D001943 |
Breast Neoplasms |
|
Benzo(a)pyrene |
1.99 | 20146248 17474063 |
| MESH:D002294 |
Carcinoma, Squamous Cell |
|
Benzo(a)pyrene |
2.14 | 20419170 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
3.01 | 20889678 |
| MESH:D004938 |
Esophageal Neoplasms |
|
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
4.64 | 20426865 |
| MESH:D004938 |
Esophageal Neoplasms |
|
Benzo(a)pyrene |
4.64 | 16530937 |
| MESH:D005911 |
Gliosis |
|
Paraquat |
6.03 | 11124998 |
| MESH:D006330 |
Heart Defects, Congenital |
|
Benzo(a)pyrene |
2.85 | 20471113 |
| MESH:D007248 |
Infertility, Male |
|
Paraquat |
3.53 | 4850670 |
| MESH:D008113 |
Liver Neoplasms |
|
Benzo(a)pyrene |
2.17 | 20195826 21137059 |
| MESH:D008175 |
Lung Neoplasms |
|
Benzo(a)pyrene |
1.57 | 20869020 18569708 18520028 18816296 20135361 20464547 20064080 17053015 6695378 |
| MESH:D009062 |
Mouth Neoplasms |
|
Benzo(a)pyrene |
3.53 | 16381670 |
| MESH:D009369 |
Neoplasms |
|
Benzo(a)pyrene |
2.35 | 11141357 |
| MESH:D009410 |
Nerve Degeneration |
|
Paraquat |
4.06 | 16893418 |
| MESH:D010300 |
Parkinson Disease |
|
Paraquat |
2.94 | 11445065 16510128 12911755 16140633 15451049 11181820 15824117 11124998 |
| MESH:D010302 |
Parkinson Disease, Secondary |
|
Paraquat |
5.08 | 16190885 |
| MESH:D011014 |
Pneumonia |
|
Paraquat |
5.19 | 12504350 |
| MESH:D011471 |
Prostatic Neoplasms |
|
Benzo(a)pyrene |
2.90 | 17292933 |
| MESH:D011658 |
Pulmonary Fibrosis |
|
Paraquat |
3.04 | 17997886 16324872 |
| MESH:D012128 |
Respiratory Distress Syndrome, Adult |
|
Paraquat |
4.43 | 11700416 |
| MESH:D012135 |
Respiratory Sounds |
|
Paraquat |
4.71 | 11874814 |
| MESH:D012162 |
Retinal Degeneration |
|
Paraquat |
4.19 | 16458197 |
| MESH:D012878 |
Skin Neoplasms |
|
Benzo(a)pyrene |
2.54 | 19755658 10029692 |
| MESH:D013274 |
Stomach Neoplasms |
|
Benzo(a)pyrene |
1.56 | 2093021 20155912 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
Benzo(a)pyrene |
2.31 | 17053015 |
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