AutismKB 2.0

Annotation Detail for HNRNPU


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:HNRNPU ( HNRPU,SAF-A,U21.1,hnRNP U )
Gene Full Name: heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
Band: 1q44
Quick LinksEntrez ID:3192; OMIM: 602869; Uniprot ID:HNRPU_HUMAN; ENSEMBL ID: ENSG00000153187; HGNC ID: 5048
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa03040Spliceosome
Pathway IDPathway Name
mRNA Processing
Gene Expression
No data
No data
Pathway IDPathway Name
500866mRNA Splicing - Major Pathway
500655Processing of Capped Intron-Containing Pre-mRNA
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of HNRNPU mRNAaffects expression 21346803
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in increased expression of HNRNPU mRNAincreases expression 18648102
C016601 4-hydroxytamoxifen 4-hydroxytamoxifen results in decreased expression of HNRNPU mRNAdecreases expression 16514628
D000082 Acetaminophen Acetaminophen affects the expression of HNRNPU mRNAaffects expression 17562736
D000643 Ammonium Chloride Ammonium Chloride affects the expression of HNRNPU mRNAaffects expression 16483693
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of HNRNPU mRNAdecreases expression 20064835
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of HNRNPU mRNAdecreases expression 19150397
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of HNRNPU mRNAincreases expression 17854601
D004052 Diethylnitrosamine RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of HNRNPU mRNA]decreases reaction|increases expression 17854601
D004958 Estradiol Estradiol results in increased expression of HNRNPU mRNAincreases expression 16514628
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of HNRNPU mRNAincreases expression 17555576
17942748
19400957
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of HNRNPU mRNAaffects cotreatment|increases expression 17942748
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of HNRNPU mRNAincreases expression 19400957
C070081 fulvestrant fulvestrant results in decreased expression of HNRNPU mRNAdecreases expression 16514628
D015741 Metribolone Metribolone promotes the reaction [NDRG1 protein binds to HNRNPU protein]affects binding|increases reaction 17220478
C006253 pirinixic acid pirinixic acid results in decreased expression of HNRNPU mRNAdecreases expression 18445702
D020849 Raloxifene Raloxifene results in decreased expression of HNRNPU mRNAdecreases expression 16514628
D013629 Tamoxifen Tamoxifen affects the expression of HNRNPU mRNAaffects expression 14699072
D013629 Tamoxifen Tamoxifen affects the expression of HNRNPU mRNAaffects expression 17555576
D013629 Tamoxifen Tamoxifen results in increased expression of HNRNPU mRNAincreases expression 19400957
D013629 Tamoxifen Tamoxifen results in increased expression of HNRNPU mRNAincreases expression 19400957
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of HNRNPU mRNAaffects cotreatment|increases expression 17942748
D014028 Tobacco Smoke Pollution Tobacco Smoke Pollution results in decreased expression of HNRNPU mRNAdecreases expression 18087596
C025643 vinclozolin vinclozolin affects the expression of HNRNPU mRNAaffects expression 19015723
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.5214745880
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.8115322242 14514962 11752688
MESH:D000138 Acidosis Ammonium Chloride 3.5218287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.9117505938
MESH:D055371 Acute Lung Injury pirinixic acid 3.0818653653
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 6.9420127859 20464547
MESH:D000230 Adenocarcinoma Estradiol 6.9411473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 6.9414692618
MESH:D002282 Adenocarcinoma, Bronchiolo-Alveolar Tobacco Smoke Pollution 5.5015814487
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 10.983712494
MESH:D000236 Adenoma Benzo(a)pyrene 10.986695378
MESH:D000236 Adenoma Diethylnitrosamine 10.9810737359 6695378
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 17.0818056438 17620307 17162532 19061943 16434500 19052882
MESH:D018248 Adenoma, Liver Cell pirinixic acid 17.0816434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 17.0816835633
MESH:D000419 Albuminuria Raloxifene 4.5517308373 17451421
MESH:D000544 Alzheimer Disease Raloxifene 2.5315800139
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.9111748828
MESH:D000799 Angioedema Acetaminophen 3.8110982225
MESH:D001008 Anxiety Disorders vinclozolin 3.6019015723
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.0319183758
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.4211256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.6415885639
MESH:D001172 Arthritis, Rheumatoid Tobacco Smoke Pollution 3.1719898480
MESH:D001284 Atrophy fulvestrant 4.8111514358
MESH:D001321 Autistic Disorder Acetaminophen 1.4218445737
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.991440618 11289319
MESH:D001778 Blood Coagulation Disorders pirinixic acid 8.6319483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 8.6312125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.7615340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.7315746008
MESH:D001930 Brain Injuries Raloxifene 4.4416580743
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 3.7517474063 20146248
MESH:D001943 Breast Neoplasms Diethylnitrosamine 3.7517474063
MESH:D001943 Breast Neoplasms Estradiol 3.7517289903 18497071 12948864 19861407 14630087 16675129 17261762 17018787
MESH:D001943 Breast Neoplasms fulvestrant 3.7518984771
MESH:D001943 Breast Neoplasms Raloxifene 3.7517952589 15572757 17595753 15758505 17440819 17893378 17261762 16912660 15775269 17049068 16837676 17242785
MESH:D001943 Breast Neoplasms Tamoxifen 3.7520544844 19155303 15565566 16202921 19115204 11161223 19221464 15668708 17893378 18629630 18815881 19189210 20065188 20135344 19410462 19142967 18425577 19189212 16818667 19011961 19059307 18855134 18821012 18351453 20859285 19084267 19244106 19066611 16273361 21138602 20390343 16873071 19288272 17261762 19289846 21152245 18997820 19200415 17440819 19487384 19103187 17049068 17242785 18984771 20005174
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 3.7520435547
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.4316111702
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.7616835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.4719066611
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 11.3016705839
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 11.303581430 7296757
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 11.303084413
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 11.3020432363 16502159 19519916 16328049 18056438 20727157 18978308 18506893 19394651 10672840 19335982 18393292 3581430 20514400 19418558 17055752 20084675 17761372 18785209 19208518 18691550 19701751 16681979 18210153 16779866 16935385 20007298 17173139 16807293 19052882 19822196 16288022 11831363 20214788 21159647 16569478 18665156 16878318 17428255 3084413 20524982 19171122 20935162 19539802 18971187 19919837 10737359 17978847 19107877 18788625 16698587 17138121 16540662 20512989 16830150 20101231 17162532 18494052 19383236
MESH:D006528 Carcinoma, Hepatocellular Estradiol 11.3016924424
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 11.3016924424
MESH:D002289 Carcinoma, Non-Small-Cell Lung Tobacco Smoke Pollution 3.4111212258
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.657296757
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 4.8620419170
MESH:D002294 Carcinoma, Squamous Cell Tobacco Smoke Pollution 4.8611212258
MESH:D002295 Carcinoma, Transitional Cell Raloxifene 9.3717572228
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 9.3717572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3416120746 18670907 18850075
MESH:D002318 Cardiovascular Diseases Raloxifene 3.4115775269
MESH:D002386 Cataract Acetaminophen 2.5510977129
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 20.776135515
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 20.777505956
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 20.7720889678
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 20.7717174075 21159647 7505956 2727394
MESH:D002471 Cell Transformation, Neoplastic Estradiol 20.7718566989
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 9.2019052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 9.2016835633
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 13.189022650 19486331
MESH:D002779 Cholestasis Ethinyl Estradiol 13.1816919318 15861022 16105132 17333356 17681005 11677210 17110522
MESH:D002779 Cholestasis pirinixic acid 13.1819176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.0812621046 15340226 15668235 8697196 16354765
MESH:D003072 Cognition Disorders Raloxifene 4.5815800139
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.0214669216 17141729
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 1.2510048152 15322242 20055451
MESH:D003456 Cryptorchidism vinclozolin 4.3014966744
MESH:D003490 Cyanosis 2,6-dinitrotoluene 3.9818551238
MESH:D003711 Demyelinating Diseases Tamoxifen 4.3219031437
MESH:D003865 Depressive Disorder, Major Raloxifene 4.1217474826
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.7712868966 2524372 8156756 11298694 18759878 11906362 14531868 8970840
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.4018249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.453621924 2952479
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 4.1820387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.1817107852
MESH:D003928 Diabetic Nephropathies Estradiol 14.8019279558
MESH:D003928 Diabetic Nephropathies Raloxifene 14.8017308373 17451421 15920148
MESH:D003928 Diabetic Nephropathies Tamoxifen 14.8019279558
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 11.8718551238 21346803
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 11.871440618 9653073 18289764 7440962 18692083 11289319 18648102 6482804 9328219 16192314 8291058 6679447 9022650
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 11.8711743745 11287661 19370779 19416960 10774834 11834606 16485898 16081117 14550746 14725611 12153990 10915739 12540782 11461765 17562736 17522070 19923254 16227642 12594235 16109766 11529661 16781746 18713872 14986274 19164858 16177239 15619225 11421492 2444490 19085960 19420014 15968718 12958197 19739265 10663392 17906064 12392966 18071297 16393943 12705907 11739529
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 11.8719107877
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 11.8720420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.0719426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.7311462148
MESH:D004487 Edema pirinixic acid 11.1912083418
MESH:D004487 Edema Raloxifene 11.1915860553
MESH:D004487 Edema Tetrachlorodibenzodioxin 11.1912711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.8715322242 18230668 16714409
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 15.1212538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Raloxifene 15.1215845917
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 15.1219031437
MESH:D016889 Endometrial Neoplasms 4-hydroxytamoxifen 12.4019148513
MESH:D016889 Endometrial Neoplasms Estradiol 12.4011473722 19148513 18566989
MESH:D016889 Endometrial Neoplasms Tamoxifen 12.4020544844 19155303 17893378 16202921
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.9810568697 9294722
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 5.0916302075
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 7.123581430
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7.1220426865
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 7.1216530937
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.9811564622
MESH:D005234 Fatty Liver Diethylnitrosamine 24.2321071580 20387270
MESH:D005234 Fatty Liver Ethinyl Estradiol 24.2315345470
MESH:D005234 Fatty Liver pirinixic acid 24.2320131406 19236843
MESH:D005234 Fatty Liver Raloxifene 24.2317473493
MESH:D005234 Fatty Liver Tamoxifen 24.2314986274 19224547
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.2116709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.4211858732
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.996705139
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.4914745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.1519069698
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 2.9120067830
MESH:D005756 Gastritis Acetaminophen 3.6516983495
MESH:D030342 Genetic Diseases, Inborn vinclozolin 4.9016973722
MESH:D005832 Genital Diseases, Male vinclozolin 5.2716417039
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 4.007505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.5710696789
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 6.3720471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.3711294989 10048152
MESH:D006331 Heart Diseases Raloxifene 3.5011110106
MESH:D006333 Heart Failure pirinixic acid 2.5120558911
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.2911000095
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 3.476705139
MESH:D006529 Hepatomegaly pirinixic acid 8.1316221962 19176532 19772884 18467677
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 8.1315340226 12621046 16120746
MESH:D006558 Herpes Genitalis Estradiol 5.0015709030
MESH:D019584 Hot Flashes Estradiol 3.7217088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.028697196 16959395 15340226 16354765 18606429
MESH:D006930 Hyperalgesia Acetaminophen 2.6616870215
MESH:D006943 Hyperglycemia pirinixic acid 3.1420558911
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.9015034207
MESH:D006973 Hypertension Raloxifene 5.1717577099 15787275
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 5.1718850075 18670907
MESH:D007021 Hypospadias Ethinyl Estradiol 3.7716945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.4212013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 11.1417937319
MESH:D007248 Infertility, Male fulvestrant 11.1411514358
MESH:D007248 Infertility, Male vinclozolin 11.1416467254
MESH:D007249 Inflammation Diethylnitrosamine 11.8018785209
MESH:D007249 Inflammation Tamoxifen 11.8019457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 11.8012878042 12200463
MESH:D007249 Inflammation Tobacco Smoke Pollution 11.8018590791
MESH:D007333 Insulin Resistance Estradiol 7.1016627594 16393666
MESH:D007333 Insulin Resistance pirinixic acid 7.1016306350
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.998074119 9022650
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.2916580747
MESH:D007674 Kidney Diseases Acetaminophen 5.8012587719 15629191
MESH:D007674 Kidney Diseases Estradiol 5.8015618244
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 17.4516705839
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 17.456582329
MESH:D007680 Kidney Neoplasms Estradiol 17.4515610895
MESH:D007680 Kidney Neoplasms Tamoxifen 17.4518625569
MESH:D007889 Leiomyoma Raloxifene 4.4516973256
MESH:D007984 Leydig Cell Tumor vinclozolin 4.7016417039
MESH:D008064 Lipidoses Tamoxifen 3.1217567588 15342952
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 2.8018522880 19638242 18665156 18407596 20032147
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.179327722 15034207
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 4.8714716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 4.8715474484
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 4.8718564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 4.8712878042
MESH:D008107 Liver Diseases Acetaminophen 3.8719460945 16611625 19014921 12587719 12969438 16610002 19784758 11587558
MESH:D008107 Liver Diseases Diethylnitrosamine 3.8717034775
MESH:D017114 Liver Failure, Acute Acetaminophen 3.2016871587 17185352
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 17.777678174
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 17.7721137059 20195826
MESH:D008113 Liver Neoplasms Diethylnitrosamine 17.7721071580 19850985 10737359 20583210 20492335 19996281 20405173 20434301 2862719 19255062 19551842 15885732 16942905 18648771 21167192 15175105 21047994 12112319 2422723 19812893 19642983 19426721 20501860 12771043 19833225 20452335 9163691 19638242 20118626 19254457 19256749 20101389 18978307 21278145 19427195 19690152 19073162 18977376 19090486 18644402 20137499 19499222 19294768 18754104
MESH:D008113 Liver Neoplasms pirinixic acid 17.7715890375 20007298 16377806
MESH:D008113 Liver Neoplasms Tamoxifen 17.7716684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 17.7716984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 13.872876784 6135515 2876786
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 13.87598648 6587162 3712494 1399818
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 13.8718093689 16267830 9362446 19539802 19126423 18544905 16842330 18775883 17942915 18079962 2563599 19009564 19004024 18282651 18253720 21159647 3124819 17854601 18164116 18308698 19519916 17174075
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 13.8712151625
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 6.5418569708 18816296 20135361 20464547 6695378 20064080 18520028 20869020 17053015
MESH:D008175 Lung Neoplasms Diethylnitrosamine 6.5420970405 6695378 21163286 20512841
MESH:D008175 Lung Neoplasms Tamoxifen 6.5418625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 6.5411884234 19555203
MESH:D008175 Lung Neoplasms Tobacco Smoke Pollution 6.5411091918 3440675 16288123 12111688
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.7219428831
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 5.8711408345 11807958 16891317 17203775
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 5.8719196722 11731420 16827153 14580682 19196723
MESH:D020149 Manganese Poisoning Estradiol 12.5519453300
MESH:D020149 Manganese Poisoning Tamoxifen 12.5519453300
MESH:D008545 Melanoma Tamoxifen 1.8719393235 12393984
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.1515990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.5319513568
MESH:D018200 Mixed Tumor, Mullerian Raloxifene 5.5315863610
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 8.6816381670
MESH:D009062 Mouth Neoplasms Tobacco Smoke Pollution 8.6815006635
MESH:D009101 Multiple Myeloma Raloxifene 3.4116497877
MESH:D009135 Muscular Diseases pirinixic acid 3.4716239165
MESH:D009203 Myocardial Infarction pirinixic acid 2.1219151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.9812213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 8.1316810080
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 8.1316411023
MESH:D009232 Myxoma Raloxifene 5.5316343187
MESH:D009336 Necrosis 2,6-dinitrotoluene 3.837678174 18551238
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 9.363581430
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 9.363581430 9029167
MESH:D009362 Neoplasm Metastasis Tamoxifen 9.3619393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.5019410462
MESH:D009369 Neoplasms Benzo(a)pyrene 4.7511141357
MESH:D009369 Neoplasms pirinixic acid 4.7517405874
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.9719189210 19200415 19196722
MESH:D009389 Neovascularization, Pathologic Estradiol 3.7017289903
MESH:D009421 Nervous System Malformations Estradiol 9.3311399458 16427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 9.3314600291
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 2.886679447
MESH:D019636 Neurodegenerative Diseases Acetaminophen 8.0618514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 8.0620387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 5.0920387270
MESH:D009765 Obesity pirinixic acid 1.8020558911
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 8.7516049721
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 8.754026338 6482804
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.993988306
MESH:D010024 Osteoporosis Raloxifene 3.3715775268 19059307 17882678
MESH:D015663 Osteoporosis, Postmenopausal Raloxifene 4.1917893378 17823083 15579764 15758505
MESH:D010051 Ovarian Neoplasms Estradiol 2.2019401270
MESH:D010146 Pain Acetaminophen 2.3516870215
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 2.4116540662
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.6511578682
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.447296757
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.2212520081
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.446228378
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.5218163543
MESH:D011230 Precancerous Conditions Diethylnitrosamine 3.512563599
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 9.3711222880 11118676 11399792 11896295
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 9.3718220299 18042343 19015723
MESH:D011469 Prostatic Diseases vinclozolin 4.9018220299
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.8420887781
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.0717292933
MESH:D011471 Prostatic Neoplasms Estradiol 2.0716740699
MESH:D011471 Prostatic Neoplasms Raloxifene 2.0716220300 16536755 15731164
MESH:D011471 Prostatic Neoplasms Tamoxifen 2.0715067354
MESH:D011472 Prostatitis vinclozolin 4.9018629315
MESH:D011537 Pruritus Ethinyl Estradiol 3.2816919318 15861022
MESH:D011693 Purpura Raloxifene 5.5315770314
MESH:D015427 Reperfusion Injury pirinixic acid 2.3619058328
MESH:D012135 Respiratory Sounds Tobacco Smoke Pollution 4.5818410779
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.8018990726
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.343692021
MESH:D012640 Seizures 2,6-dinitrotoluene 2.5018551238
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 9.3919755658 10029692
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 9.3916192470
MESH:D012878 Skin Neoplasms Tobacco Smoke Pollution 9.3918590791
MESH:D013088 Spermatocele Ethinyl Estradiol 11.4716709447
MESH:D013088 Spermatocele Tamoxifen 11.4716709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 4.0019457130
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 2.3220155912 2093021
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 2.3218456281
MESH:D020521 Stroke Raloxifene 3.7816837676
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.5811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.1115669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.8712697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 7.001399818 6587162 3712494 7505956 6582329
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 7.007505956
MESH:D013978 Tibial Fractures Estradiol 13.6219048282
MESH:D013978 Tibial Fractures Raloxifene 13.6219048282
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 19.6816049721
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 19.688074119
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 19.6817053015
MESH:D001749 Urinary Bladder Neoplasms Raloxifene 19.6817572228
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 19.6816712894 8653321 17572228
MESH:D001749 Urinary Bladder Neoplasms Tobacco Smoke Pollution 19.6812846360
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 4.2810091137
MESH:D014581 Urticaria Acetaminophen 2.9410982225
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.2614692618
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.5712125929
MESH:D054556 Venous Thromboembolism Raloxifene 5.1816837676
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.5014671159 15869587
MESH:D014846 Vulvar Neoplasms Raloxifene 5.5316343187
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.2215886252
Pathway ID Pathway Name
REACT:71 Gene Expression
REACT:1675 mRNA Processing
KEGG:03040 Spliceosome
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved