Annotation Detail for APBA2
Basic Information
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| Gene Symbol: | APBA2 ( D15S1518E,HsT16821,LIN-10,MGC99508,MGC:14091,MINT2,X11L ) |
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| Gene Full Name: | amyloid beta (A4) precursor protein-binding, family A, member 2 |
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| Band: | 15q13.1 |
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| Quick Links | Entrez ID:321; OMIM: 602712; Uniprot ID:APBA2_HUMAN; ENSEMBL ID: ENSG00000034053; HGNC ID: 579 |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Pathway ID | Pathway Name |
|---|
| P00003 | Alzheimer disease-amyloid secretase pathway |
| Desease ID | Desease Name |
|---|
| 2069 | Schizophrenia |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| C023514 |
2,6-dinitrotoluene |
2,6-dinitrotoluene affects the expression of APBA2 mRNA | affects expression | 21346803
|
| D000643 |
Ammonium Chloride |
Ammonium Chloride affects the expression of APBA2 mRNA | affects expression | 16483693
|
| D005472 |
Fluorouracil |
APBA2 protein affects the susceptibility to Fluorouracil | affects response to substance | 16217747
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000138 |
Acidosis |
|
Ammonium Chloride |
4.30 | 18287403 |
| MESH:D000230 |
Adenocarcinoma |
|
Fluorouracil |
2.50 | 17638652 |
| MESH:D000740 |
Anemia |
|
Fluorouracil |
4.16 | 17963324 15504547 16511603 |
| MESH:D001943 |
Breast Neoplasms |
|
Fluorouracil |
2.43 | 16110121 16557594 18357371 16595493 18608205 15136595 19217205 |
| MESH:D002276 |
Carcinoid Tumor |
|
Fluorouracil |
5.53 | 16051944 |
| MESH:D002277 |
Carcinoma |
|
Fluorouracil |
3.93 | 17121937 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
2,6-dinitrotoluene |
3.24 | 16705839 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
Fluorouracil |
3.24 | 17971768 16332177 16799960 18930000 17088986 17045692 |
| MESH:D002292 |
Carcinoma, Renal Cell |
|
Fluorouracil |
3.18 | 18695887 |
| MESH:D002294 |
Carcinoma, Squamous Cell |
|
Fluorouracil |
2.58 | 18986760 16757204 17066447 16280240 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
2,6-dinitrotoluene |
3.06 | 6135515 |
| MESH:D003110 |
Colonic Neoplasms |
|
Fluorouracil |
2.29 | 16340194 16510598 17287894 17725105 17172411 18772588 17016597 15001691 17018589 17169374 |
| MESH:D015179 |
Colorectal Neoplasms |
|
Fluorouracil |
2.00 | 17594712 17695437 18949393 20501625 15289873 16391804 15148649 18448328 16303861 17255274 17016601 18802399 17454858 14970324 18288408 16524972 18383874 16331619 18509181 17401013 17094418 16282729 |
| MESH:D003490 |
Cyanosis |
|
2,6-dinitrotoluene |
4.67 | 18551238 |
| MESH:D007644 |
Darier Disease |
|
Fluorouracil |
5.53 | 16733453 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
2,6-dinitrotoluene |
2.06 | 18551238 21346803 |
| MESH:D004938 |
Esophageal Neoplasms |
|
Fluorouracil |
2.53 | 16481741 15173087 16785472 16337965 17638652 |
| MESH:D005910 |
Glioma |
|
Fluorouracil |
3.00 | 16145905 |
| MESH:D006258 |
Head and Neck Neoplasms |
|
Fluorouracil |
3.67 | 15162350 18337622 15102660 |
| MESH:D007680 |
Kidney Neoplasms |
|
2,6-dinitrotoluene |
8.80 | 16705839 |
| MESH:D007680 |
Kidney Neoplasms |
|
Fluorouracil |
8.80 | 16985049 |
| MESH:D008113 |
Liver Neoplasms |
|
2,6-dinitrotoluene |
5.10 | 7678174 |
| MESH:D008113 |
Liver Neoplasms |
|
Fluorouracil |
5.10 | 15113037 17045692 16603448 18383874 |
| MESH:D008114 |
Liver Neoplasms, Experimental |
|
2,6-dinitrotoluene |
2.79 | 2876786 2876784 6135515 |
| MESH:D008175 |
Lung Neoplasms |
|
Fluorouracil |
2.01 | 15246190 |
| MESH:D008178 |
Lupus Erythematosus, Cutaneous |
|
Fluorouracil |
5.53 | 15086387 |
| MESH:D009062 |
Mouth Neoplasms |
|
Fluorouracil |
3.98 | 16757204 18986760 |
| MESH:D009336 |
Necrosis |
|
2,6-dinitrotoluene |
4.60 | 18551238 7678174 |
| MESH:D009369 |
Neoplasms |
|
Fluorouracil |
2.79 | 18239605 18600527 16928823 |
| MESH:D020258 |
Neurotoxicity Syndromes |
|
Fluorouracil |
3.72 | 16436463 |
| MESH:D009784 |
Occupational Diseases |
|
2,6-dinitrotoluene |
3.88 | 16049721 |
| MESH:D010190 |
Pancreatic Neoplasms |
|
Fluorouracil |
2.78 | 16929163 19003803 16500647 15113037 |
| MESH:D011471 |
Prostatic Neoplasms |
|
Fluorouracil |
3.34 | 19082440 18626508 |
| MESH:D012004 |
Rectal Neoplasms |
|
Fluorouracil |
4.43 | 15538739 18286688 16160472 18722050 |
| MESH:D012640 |
Seizures |
|
2,6-dinitrotoluene |
2.82 | 18551238 |
| MESH:D013274 |
Stomach Neoplasms |
|
Fluorouracil |
2.00 | 16951190 19084572 19015929 17498489 18567086 17172411 18396642 15786421 16424979 17522103 |
| MESH:D014062 |
Tongue Neoplasms |
|
Fluorouracil |
4.44 | 16280240 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
2,6-dinitrotoluene |
2.42 | 16049721 |
| MESH:D014571 |
Urologic Neoplasms |
|
2,6-dinitrotoluene |
5.06 | 10091137 |
| MESH:D002583 |
Uterine Cervical Neoplasms |
|
Fluorouracil |
4.33 | 16803524 |
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