AutismKB 2.0

Annotation Detail for HOXD8


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Basic Information Top
Gene Symbol:HOXD8 ( HOX4,HOX4E,HOX5.4 )
Gene Full Name: homeobox D8
Band: 2q31.1
Quick LinksEntrez ID:3234; OMIM: 142985; Uniprot ID:HXD8_HUMAN; ENSEMBL ID: ENSG00000175879; HGNC ID: 5139
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of HOXD8 mRNAaffects expression 17562736
D004041 Dietary Fats Dietary Fats results in increased expression of HOXD8 mRNAincreases expression 18042831
D004054 Diethylstilbestrol Diethylstilbestrol results in decreased expression of HOXD8 mRNAdecreases expression 15289156
D004958 Estradiol Estradiol results in decreased expression of HOXD8 mRNAdecreases expression 15289156
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of HOXD8 mRNAaffects expression 17555576
D019833 Genistein Genistein results in decreased expression of HOXD8 mRNAdecreases expression 15289156
C008493 methylselenic acid methylselenic acid results in increased expression of HOXD8 mRNAincreases expression 12517777
C041786 palm oil palm oil results in increased expression of HOXD8 mRNAincreases expression 18042831
C017947 sodium arsenite sodium arsenite results in increased expression of HOXD8 mRNAincreases expression 16322246
D013629 Tamoxifen Tamoxifen affects the expression of HOXD8 mRNAaffects expression 17555576
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of HOXD8 mRNAdecreases expression 19897914
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of HOXD8 mRNAincreases expression 17942748
D014212 Tretinoin Tretinoin results in decreased expression of HOXD8 mRNAdecreases expression 19897914
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.7214745880
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 3.0011752688 14514962 15322242
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.1217505938
MESH:D000230 Adenocarcinoma Estradiol 7.2211473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 7.2214692618
MESH:D000230 Adenocarcinoma Genistein 7.2211473722
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 3.5316835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.8715276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 5.0817306315 16712894
MESH:D000505 Alopecia Tretinoin 3.7015955085
MESH:D000686 Amyloidosis Diethylstilbestrol 4.6115469931
MESH:D000740 Anemia Tetrachlorodibenzodioxin 3.0511748828
MESH:D000799 Angioedema Acetaminophen 4.0210982225
MESH:D001161 Arteriosclerosis Dietary Fats 10.3815238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 10.3811256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 7.4215885639
MESH:D001169 Arthritis, Experimental Tretinoin 7.4216412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.2916292516
MESH:D001249 Asthma Tretinoin 2.3716456186
MESH:D001321 Autistic Disorder Acetaminophen 1.4118445737
MESH:D001471 Barrett Esophagus Tretinoin 4.5316935849
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 9.3112125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 9.3116206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.9615340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.8315746008
MESH:D001943 Breast Neoplasms Dietary Fats 3.8420435547
MESH:D001943 Breast Neoplasms Diethylstilbestrol 3.8415324884 17129689
MESH:D001943 Breast Neoplasms Estradiol 3.8417018787 12948864 18497071 17289903 19861407 14630087 16675129 17261762
MESH:D001943 Breast Neoplasms Genistein 3.8416873071 16541309 17200150
MESH:D001943 Breast Neoplasms Tamoxifen 3.8417440819 19221464 16873071 20544844 19410462 18629630 16818667 18351453 17261762 19142967 21152245 17893378 19200415 21138602 20390343 19115204 19487384 11161223 18984771 19189210 20005174 20135344 18997820 19155303 18425577 19189212 17242785 16202921 19289846 19084267 18821012 18855134 20065188 15565566 20859285 19011961 19066611 18815881 17049068 15668708 19288272 16273361 19244106 19103187 19059307
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 3.8420435547
MESH:D001943 Breast Neoplasms Tretinoin 3.8416166294 16443354 16873071
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.7416813970
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.6216111702
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.8916835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.6419066611
MESH:D018236 Carcinoma, Embryonal Tretinoin 5.3316168501
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 14.363084413
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 14.3616924424 15948411
MESH:D006528 Carcinoma, Hepatocellular Estradiol 14.3616924424
MESH:D006528 Carcinoma, Hepatocellular Genistein 14.3616924424
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 14.3616507464 17306315 15276417
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 14.3616924424
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 14.361917145
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 4.7818572023
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 4.7816096774 16051514
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.7217572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.4218850075 18670907 16120746
MESH:D002318 Cardiovascular Diseases Genistein 3.3816332659
MESH:D002386 Cataract Acetaminophen 7.4310977129
MESH:D002386 Cataract Tretinoin 7.4317460283
MESH:D002471 Cell Transformation, Neoplastic Estradiol 6.9918566989
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 6.9920056578 19524636
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.7416129372
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.2616835633
MESH:D002779 Cholestasis Ethinyl Estradiol 2.9511677210 16105132 15861022 17681005 17333356 16919318 17110522
MESH:D002822 Choriocarcinoma Tretinoin 5.3316461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.9012621046 8697196 15668235 15340226 16354765
MESH:D002972 Cleft Palate Tretinoin 5.909407595
MESH:D003092 Colitis Tretinoin 3.8417035595
MESH:D003110 Colonic Neoplasms Genistein 2.3017182828
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.1617141729 14669216
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.4820055451 10048152 15322242
MESH:D019465 Craniofacial Abnormalities Tretinoin 2.489142499 17551590 9125849 10589399 9224671 16925845 9664655 9211117 14991402 8800419
MESH:D003456 Cryptorchidism Diethylstilbestrol 4.6812952375 16002989
MESH:D003711 Demyelinating Diseases Tamoxifen 4.5019031437
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 4.4116647724
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.4117107852
MESH:D003928 Diabetic Nephropathies Estradiol 9.1719279558
MESH:D003928 Diabetic Nephropathies Tamoxifen 9.1719279558
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 3.6511743745 12958197 19370779 17522070 11739529 10915739 17562736 19739265 15619225 17906064 10663392 12705907 16393943 11461765 11529661 16109766 18713872 11421492 12392966 14986274 12540782 14725611 19420014 16227642 10774834 16177239 12153990 18071297 14550746 11834606 16485898 19085960 2444490 16781746 19164858 15968718 12594235 19416960 19923254 11287661 16081117
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 3.6520420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.2719426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.8411462148
MESH:D050171 Dyslipidemias Dietary Fats 3.5318367378
MESH:D004487 Edema Tetrachlorodibenzodioxin 2.4811000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 12.5316714409 15322242 18230668
MESH:D004489 Edema, Cardiac Tretinoin 12.5318230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 9.3712538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 9.3719031437
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 12.4116402032
MESH:D004714 Endometrial Hyperplasia Genistein 12.4116402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 24.1016804899 15700306
MESH:D016889 Endometrial Neoplasms Estradiol 24.1018566989 11473722 19148513
MESH:D016889 Endometrial Neoplasms Genistein 24.1011473722
MESH:D016889 Endometrial Neoplasms Tamoxifen 24.1020544844 17893378 19155303 16202921
MESH:D016889 Endometrial Neoplasms Tretinoin 24.1016569247
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.129294722 10568697
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 9.1111564622
MESH:D005124 Eye Abnormalities Tretinoin 9.119664655 16938888
MESH:D005234 Fatty Liver Dietary Fats 13.7617967931 19551842 18296743 19004024
MESH:D005234 Fatty Liver Ethinyl Estradiol 13.7615345470
MESH:D005234 Fatty Liver Tamoxifen 13.7619224547 14986274
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 8.4216611131 16513791 16002989 15751030 16534752
MESH:D052776 Female Urogenital Diseases Tamoxifen 8.4216709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.5911858732
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.6814745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.3419069698
MESH:D005355 Fibrosis Dietary Fats 15.6118296743
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 15.6120067830
MESH:D005355 Fibrosis Tretinoin 15.6117994277
MESH:D005756 Gastritis Acetaminophen 3.8516983495
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 13.3416452187
MESH:D005833 Genital Neoplasms, Female sodium arsenite 13.3416452187
MESH:D005909 Glioblastoma Genistein 7.4416598420
MESH:D005909 Glioblastoma Tretinoin 7.4417312396
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.7710696789
MESH:D006258 Head and Neck Neoplasms Tretinoin 3.2616096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 5.3316084493
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.7211294989 10048152
MESH:D006330 Heart Defects, Congenital Tretinoin 6.7214991402 9664655
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.4411000095
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 3.0315340226 12621046 16120746
MESH:D006558 Herpes Genitalis Estradiol 5.2115709030
MESH:D006689 Hodgkin Disease sodium arsenite 3.2512676792
MESH:D019584 Hot Flashes Estradiol 3.9317088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.228697196 18606429 15340226 16354765 16959395
MESH:D006930 Hyperalgesia Acetaminophen 7.9216870215
MESH:D006930 Hyperalgesia Tretinoin 7.9216870215
MESH:D006937 Hypercholesterolemia Dietary Fats 3.7021332399
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.7116778211
MESH:D006949 Hyperlipidemias Dietary Fats 3.7321332399
MESH:D006965 Hyperplasia Diethylstilbestrol 4.5712960047 14722030
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 1.9418850075 18670907
MESH:D007021 Hypospadias Diethylstilbestrol 11.7116002989
MESH:D007021 Hypospadias Ethinyl Estradiol 11.7116945680 16569931
MESH:D007246 Infertility Diethylstilbestrol 4.4815036965
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.5812013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 6.8817937319
MESH:D007248 Infertility, Male sodium arsenite 6.8812646999 15346721
MESH:D007249 Inflammation Dietary Fats 8.5920412841
MESH:D007249 Inflammation Tamoxifen 8.5919457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 8.5912878042 12200463
MESH:D007333 Insulin Resistance Dietary Fats 7.6018457598 11836018
MESH:D007333 Insulin Resistance Estradiol 7.6016393666 16627594
MESH:D007410 Intestinal Diseases Tretinoin 3.9017994277
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 10.3016580747
MESH:D007569 Jaw Abnormalities Tretinoin 10.3015992940 17551590
MESH:D007674 Kidney Diseases Acetaminophen 10.3915629191 12587719
MESH:D007674 Kidney Diseases Estradiol 10.3915618244
MESH:D007674 Kidney Diseases sodium arsenite 10.3920008137
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 13.0215003126 14681315 16762066
MESH:D007680 Kidney Neoplasms Estradiol 13.0215610895
MESH:D007680 Kidney Neoplasms Tamoxifen 13.0218625569
MESH:D007859 Learning Disorders Diethylstilbestrol 4.2017184923
MESH:D007938 Leukemia Genistein 6.5817468513 18980019
MESH:D007938 Leukemia Tretinoin 6.5817143497
MESH:D007951 Leukemia, Myeloid Tretinoin 3.8116482212 19285840 16932348
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 2.0917596541 16294345 19850784
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 3.2217301526 16891316 19225113 17107899 16140955 19642359 17506722 17712046 12679006 9834237 19029980 17361223 16935935 16823087 16766008 19075265 17217047 19035177 15748426 16788101 16331271 17649720 17368321 17294898 17339181
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.389224671
MESH:D008064 Lipidoses Tamoxifen 3.2317567588 15342952
MESH:D008103 Liver Cirrhosis Dietary Fats 2.9318296743
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 6.8614659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental Genistein 6.8617823541
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 6.8618564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 6.8612878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 6.8616248980 18397230
MESH:D008107 Liver Diseases Acetaminophen 1.6519784758 16610002 12969438 11587558 19460945 12587719 19014921 16611625
MESH:D017114 Liver Failure, Acute Acetaminophen 3.3417185352 16871587
MESH:D008113 Liver Neoplasms Diethylstilbestrol 11.0416712894 15890375
MESH:D008113 Liver Neoplasms sodium arsenite 11.0415276417 16712894
MESH:D008113 Liver Neoplasms Tamoxifen 11.0416684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 11.0416984957
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 2.1712151625
MESH:D008171 Lung Diseases sodium arsenite 3.2419095001
MESH:D008175 Lung Neoplasms sodium arsenite 3.4517306315 15276417 16712894 17077188 19931552
MESH:D008175 Lung Neoplasms Tamoxifen 3.4518625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 3.4519555203 11884234
MESH:D008181 Lupus Nephritis Diethylstilbestrol 5.3015166399
MESH:D008223 Lymphoma Diethylstilbestrol 3.5515700306
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 5.6916002989
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.9119428831
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 10.3916891317 11807958 17203775 11408345
MESH:D008325 Mammary Neoplasms, Experimental Genistein 10.3914578162 12929590
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 10.3919196722 14580682 19196723 11731420 16827153
MESH:D020149 Manganese Poisoning Estradiol 13.2419453300
MESH:D020149 Manganese Poisoning Tamoxifen 13.2419453300
MESH:D008527 Medulloblastoma Tretinoin 2.8217453147
MESH:D008545 Melanoma sodium arsenite 5.2016487513 19082730
MESH:D008545 Melanoma Tamoxifen 5.2012393984 19393235
MESH:D008545 Melanoma Tretinoin 5.2016752155
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.3415990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.7119513568
MESH:D008591 Meningomyelocele Tretinoin 4.5616940565
MESH:D009190 Myelodysplastic Syndromes Tretinoin 3.1417596541
MESH:D009203 Myocardial Infarction Genistein 2.9017141266
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.1112213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 8.8016810080
MESH:D015428 Myocardial Reperfusion Injury Genistein 8.8017141266
MESH:D009362 Neoplasm Metastasis Tamoxifen 2.5819393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.5519410462
MESH:D009369 Neoplasms Diethylstilbestrol 8.6515313581
MESH:D009369 Neoplasms sodium arsenite 8.6511559025
MESH:D009369 Neoplasms Tretinoin 8.6516594593 16946489
MESH:D009374 Neoplasms, Experimental sodium arsenite 3.8020056578
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 4.1719200415 19189210 19196722
MESH:D009389 Neovascularization, Pathologic Estradiol 3.8917289903
MESH:D009421 Nervous System Malformations Diethylstilbestrol 32.2311399458
MESH:D009421 Nervous System Malformations Estradiol 32.2316427766 11399458
MESH:D009421 Nervous System Malformations Genistein 32.2316427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 32.2314600291
MESH:D009421 Nervous System Malformations Tretinoin 32.239125849
MESH:D009436 Neural Tube Defects sodium arsenite 7.5412854658
MESH:D009436 Neural Tube Defects Tretinoin 7.549142499
MESH:D019636 Neurodegenerative Diseases Acetaminophen 2.9618514411
MESH:D009765 Obesity Dietary Fats 2.3111836018 17217161 20132043 21332399 16723640 20518802 18457598 19632207 18674790
MESH:D010024 Osteoporosis Genistein 3.3219401787
MESH:D015663 Osteoporosis, Postmenopausal Genistein 4.2016169203
MESH:D010051 Ovarian Neoplasms Estradiol 11.5619401270
MESH:D010051 Ovarian Neoplasms Genistein 11.5619005980
MESH:D010051 Ovarian Neoplasms sodium arsenite 11.5617306315 15276417
MESH:D010051 Ovarian Neoplasms Tretinoin 11.5616936753
MESH:D010146 Pain Acetaminophen 6.8916870215
MESH:D010146 Pain Tretinoin 6.8916870215
MESH:D010190 Pancreatic Neoplasms Tretinoin 2.5015976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.8011578682
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.4212520081
MESH:D010900 Pituitary Diseases Diethylstilbestrol 5.3414722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 4.8115687265 16977796
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.6918163543
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 10.0917184923
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 10.0911399792 11222880 11118676 11896295
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.9920887781
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 1.9017136230 15846301 15046698
MESH:D011471 Prostatic Neoplasms Estradiol 1.9016740699
MESH:D011471 Prostatic Neoplasms Genistein 1.9015256057 15378649 16925846
MESH:D011471 Prostatic Neoplasms methylselenic acid 1.9016205645
MESH:D011471 Prostatic Neoplasms sodium arsenite 1.9016039940
MESH:D011471 Prostatic Neoplasms Tamoxifen 1.9015067354
MESH:D011507 Proteinuria Tretinoin 3.7216636307
MESH:D011537 Pruritus Ethinyl Estradiol 3.4715861022 16919318
MESH:D011625 Pterygium Tretinoin 4.9516723453
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.9618990726
MESH:D012208 Rhabdomyosarcoma Tretinoin 4.2216283617 16116481
MESH:D012878 Skin Neoplasms sodium arsenite 9.7119524636 18572023
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 9.7116192470
MESH:D012878 Skin Neoplasms Tretinoin 9.7116467112
MESH:D013088 Spermatocele Diethylstilbestrol 21.2016002989 16709447
MESH:D013088 Spermatocele Ethinyl Estradiol 21.2016709447
MESH:D013088 Spermatocele Tamoxifen 21.2016709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 4.1919457130
MESH:D016135 Spinal Dysraphism sodium arsenite 3.8812854658
MESH:D013274 Stomach Neoplasms Tretinoin 1.8017261132
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.7411994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.2515669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 4.0812697716
MESH:D013964 Thyroid Neoplasms Tretinoin 3.1116026305 17045167
MESH:D013978 Tibial Fractures Estradiol 4.8619048282
MESH:D014062 Tongue Neoplasms Tretinoin 3.8916051514
MESH:D014376 Tuberculosis Tretinoin 3.2916040207
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 8.6216452187 17306315 16712894
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 8.6211723127 16712894 16452187 17306315
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 8.6217572228 16712894 8653321
MESH:D014581 Urticaria Acetaminophen 3.0910982225
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 16.5016175088
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 16.5011813266
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 16.5016129372
MESH:D014591 Uterine Diseases Diethylstilbestrol 5.3414652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 9.9015809267 16690809
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 9.9014692618
MESH:D014604 Uveal Neoplasms Tretinoin 4.7816752155
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 4.5716002989 16513791
MESH:D014652 Vascular Diseases sodium arsenite 4.5817056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.7712125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.6514671159 15869587
MESH:D014820 Vitiligo Tretinoin 4.1816761959
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.4215886252
MESH:D015430 Weight Gain Dietary Fats 3.8316723640
MESH:D009396 Wilms Tumor Tretinoin 4.0716287080
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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