AutismKB 2.0

Annotation Detail for APC


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Basic Information Top
Gene Symbol:APC ( BTPS2,DP2,DP2.5,DP3,GS )
Gene Full Name: adenomatous polyposis coli
Band: 5q22.2
Quick LinksEntrez ID:324; OMIM: 611731; Uniprot ID:APC_HUMAN; ENSEMBL ID: ENSG00000134982; HGNC ID: 583
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04310Wnt signaling pathway
hsa04810Regulation of actin cytoskeleton
hsa05213Endometrial cancer
hsa05210Colorectal cancer
hsa05217Basal cell carcinoma
hsa05200Pathways in cancer
Pathway IDPathway Name
Signaling by Wnt
Apoptosis
Pathway IDPathway Name
200032Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
200064Canonical Wnt signaling pathway
200106Regulation of Wnt-mediated beta catenin signaling and target gene transcription
200101Direct p53 effectors
200052Presenilin action in Notch and Wnt signaling
200057CDC42 signaling events
200059Regulation of CDC42 activity
Pathway IDPathway Name
P00005Angiogenesis
P00057Wnt signaling pathway
No data
Related Diseases/Disorders Top
Desease IDDesease Name
Cancers
Cancers of the digestive system
H00018Gastric cancer
H00017Esophageal cancer
H00047Gallbladder cancer
H00044Cancer of the anal canal
Desease IDDesease Name
1832Congenital abnormality
1916Pervasive development disorder
1934Cancer
2069Schizophrenia
2094Ulcerative colitis
2164Barrett's esophagus
Desease Name
colon adenomas/carcinomas
familial adenomatous polyposis.
diet lifestyle and risk of colon cancer
Venous Thrombosis
decreased apoptotic level
colorectal cancer
CARDIOVASCULAR
colorectal adenocarcinomas
CANCER
PSYCH
stomach cancer
severe desmoid phenotype
beta-catenin
late onset of familial adenomatous polyposis
late onset familial adenomatous polyposis
colorectal adenomas
hepatocellular carcinoma
Adenomatous Polyposis Coli
Autism
adenomatous polyposis
No data
Desease Name
Desmoid disease, hereditary
Adenoma, periampullary
Hepatoblastoma
Brain tumor-polyposis syndrome 2
Colorectal cancer, somatic
Gardner syndrome
Adenomatous polyposis coli
Gastric cancer, somatic
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of APC mRNAaffects expression 21346803
C026137 3-hydroxyacetanilide 3-hydroxyacetanilide results in decreased expression of APC mRNAdecreases expression 18544908
C027576 4-hydroxy-2-nonenal 4-hydroxy-2-nonenal results in decreased expression of APC mRNAdecreases expression 12419474
D000082 Acetaminophen Acetaminophen affects the expression of APC mRNAaffects expression 17562736
D000082 Acetaminophen Acetaminophen results in decreased expression of APC mRNAdecreases expression 18544908
D000643 Ammonium Chloride Ammonium Chloride affects the expression of APC mRNAaffects expression 16483693
D001397 Azoxymethane Azoxymethane results in decreased expression of APC mRNAdecreases expression 12458338
11076880
D001397 Azoxymethane Etodolac inhibits the reaction [Azoxymethane results in decreased expression of APC mRNA]decreases expression|decreases reaction 11076880
D001397 Azoxymethane Sulindac inhibits the reaction [Azoxymethane results in decreased expression of APC mRNA]decreases expression|decreases reaction 12458338
11076880
D002713 Chlorine [Ozone co-treated with Chlorine] affects the expression of APC mRNAaffects cotreatment|affects expression 18636392
D003010 Clorgyline Clorgyline results in increased expression of APC mRNAincreases expression 19691856
D003474 Curcumin Curcumin results in decreased expression of APC mRNAdecreases expression 15713895
C014347 decitabine decitabine affects the methylation of APC promoteraffects methylation 17882284
C014347 decitabine decitabine results in decreased methylation of APC promoterdecreases methylation 18676679
D016264 Dextran Sulfate APC affects the susceptibility to Dextran Sulfateaffects response to substance 16049979
D004052 Diethylnitrosamine Diethylnitrosamine results in decreased expression of APC mRNAdecreases expression 20360939
D005038 Ethylnitrosourea Ethylnitrosourea results in increased mutagenesis of APC geneincreases mutagenesis 16724327
D017308 Etodolac Etodolac inhibits the reaction [Azoxymethane results in decreased expression of APC mRNA]decreases expression|decreases reaction 11076880
D006830 Hydralazine Hydralazine results in decreased methylation of APC promoterdecreases methylation 15862127
D006861 Hydrogen Peroxide Hydrogen Peroxide results in decreased expression of APC mRNAdecreases expression 12419474
D007213 Indomethacin Indomethacin results in increased expression of APC mRNAincreases expression 15963497
D007213 Indomethacin Indomethacin results in increased expression of APC proteinincreases expression 15963497
D007213 Indomethacin Indomethacin inhibits the reaction [APC gene mutant form results in decreased expression of LPL mRNA]decreases expression|decreases reaction 17546600
D007213 Indomethacin Indomethacin inhibits the reaction [APC gene mutant form results in increased expression of TNF mRNA]decreases reaction|increases expression 17546600
C051890 irinotecan irinotecan metabolite results in decreased expression of APC mRNAdecreases expression 15956246
C051890 irinotecan irinotecan results in decreased expression of APC mRNAdecreases expression 15956246
D018817 N-Methyl-3,4-methylenedioxyamphetamine N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of APC mRNAincreases expression 19285098
D008769 Methylnitronitrosoguanidine Methylnitronitrosoguanidine results in increased expression of APC mRNAincreases expression 12634122
D008770 Methylnitrosourea APC gene mutant form results in increased susceptibility to Methylnitrosoureaincreases response to substance 12096346
D010126 Ozone [Ozone co-treated with Chlorine] affects the expression of APC mRNAaffects cotreatment|affects expression 18636392
D011794 Quercetin Quercetin results in increased expression of APC mRNAincreases expression 14715546
D012643 Selenium Selenium results in decreased expression of APC mRNAdecreases expression 19244175
D018038 Sodium Selenite Sodium Selenite results in decreased methylation of APC promoterdecreases methylation 18676679
D018038 Sodium Selenite Sodium Selenite results in increased expression of APC mRNAincreases expression 18676679
D013467 Sulindac Sulindac inhibits the reaction [Azoxymethane results in decreased expression of APC mRNA]decreases expression|decreases reaction 12458338
11076880
D013467 Sulindac Sulindac results in increased expression of APC proteinincreases expression 12458338
C402769 tipifarnib tipifarnib results in increased expression of APC mRNAincreases expression 16403772
D014212 Tretinoin APC protein affects the chemical synthesis of Tretinoinaffects chemical synthesis 16938888
D014212 Tretinoin APC protein affects the metabolism of Tretinoinaffects metabolic processing 16885356
D014212 Tretinoin Tretinoin inhibits the reaction [APC gene mutant form results in increased expression of CEBPB mRNA]decreases reaction|increases expression 16699180
D014501 Uranium Uranium affects the expression of APC mRNAaffects expression 15672453
C005460 uranyl acetate uranyl acetate affects the expression of APC mRNAaffects expression 15672453
C025643 vinclozolin vinclozolin affects the expression of APC mRNAaffects expression 19015723
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Sulindac 5.2014745880
MESH:D000138 Acidosis Ammonium Chloride 3.2618287403
MESH:D058186 Acute Kidney Injury Sulindac 4.057897758
MESH:D055371 Acute Lung Injury Chlorine 4.0520601635
MESH:D000230 Adenocarcinoma marker/mechanism 15639718
MESH:D000230 Adenocarcinoma Indomethacin 6.9516537180
MESH:D000230 Adenocarcinoma Methylnitrosourea 6.9515688392 15113128
MESH:D000230 Adenocarcinoma Sulindac 6.9511910360
MESH:D000236 Adenoma marker/mechanism 19092804
MESH:D000236 Adenoma Diethylnitrosamine 14.686695378 10737359
MESH:D000236 Adenoma Ethylnitrosourea 14.686695378
MESH:D000236 Adenoma Indomethacin 14.6811497255
MESH:D000236 Adenoma Sulindac 14.6810223192
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 3.6119052882 19061943 18056438 16434500 17620307 17162532
MESH:D011125 Adenomatous Polyposis Coli marker/mechanism 8071957 11040535 12394442 18704758 11766074 17942926
MESH:D011125 Adenomatous Polyposis Coli Sulindac 4.3417611924 12394442 11874996 16460482 15623613 11535846 19003578
MESH:D019973 Alcohol-Related Disorders Curcumin 4.7817887948
OMIM:607154 ALLERGIC RHINITIS Etodolac 5.5416979129
MESH:D000505 Alopecia Tretinoin 3.3815955085
MESH:D016301 Alveolar Bone Loss Indomethacin 5.0717225004
MESH:D000544 Alzheimer Disease Curcumin 6.3215590663
MESH:D000544 Alzheimer Disease Indomethacin 6.3217627676 15579461
MESH:D000544 Alzheimer Disease Ozone 6.3215513908
MESH:D000690 Amyotrophic Lateral Sclerosis 4-hydroxy-2-nonenal 3.9210965797
MESH:D000743 Anemia, Hemolytic Quercetin 3.9817084956
MESH:D000799 Angioedema Acetaminophen 3.5410982225
MESH:D000855 Anorexia N-Methyl-3,4-methylenedioxyamphetamine 5.0615146954
MESH:D001008 Anxiety Disorders vinclozolin 3.4119015723
MESH:D001014 Aortic Aneurysm Indomethacin 4.5710231640
MESH:D017544 Aortic Aneurysm, Abdominal Indomethacin 4.5810388637
MESH:D018771 Arthralgia Indomethacin 4.872160914
MESH:D001169 Arthritis, Experimental Tretinoin 2.9016412693
MESH:D001172 Arthritis, Rheumatoid Curcumin 9.9816807698
MESH:D001172 Arthritis, Rheumatoid Indomethacin 9.9811248219
MESH:D001172 Arthritis, Rheumatoid Ozone 9.9815570426
MESH:D001172 Arthritis, Rheumatoid Tretinoin 9.9816292516
MESH:D001249 Asthma Ozone 4.6416373670 17854713
MESH:D001249 Asthma Tretinoin 4.6416456186
MESH:D001260 Ataxia Telangiectasia Quercetin 4.6815336622
MESH:D050197 Atherosclerosis Curcumin 3.1518704882
MESH:D001321 Autistic Disorder marker/mechanism 17221838 8071957
MESH:D001321 Autistic Disorder Acetaminophen 1.4518445737
MESH:D001327 Autoimmune Diseases Curcumin 9.9019761891
MESH:D001327 Autoimmune Diseases Quercetin 9.9019761891
MESH:D001471 Barrett Esophagus Tretinoin 4.1216935849
MESH:D001477 Bartter Syndrome Indomethacin 4.6910684365
MESH:D001778 Blood Coagulation Disorders Tretinoin 3.3516197459 16206674
MESH:D001913 Bowen's Disease Sulindac 5.0511207687
MESH:D001927 Brain Diseases Ethylnitrosourea 4.6214991843
MESH:D001929 Brain Edema Indomethacin 4.7211481608
MESH:D002545 Brain Ischemia Curcumin 9.3916770732
MESH:D002545 Brain Ischemia Indomethacin 9.3912524144
MESH:D001932 Brain Neoplasms Curcumin 8.2917596214
MESH:D001932 Brain Neoplasms Ethylnitrosourea 8.2916357521 16651633 15144691 16436596 18412241
MESH:D001943 Breast Neoplasms Curcumin 4.4816243823 19250217 18462866 18593918
MESH:D001943 Breast Neoplasms decitabine 4.4819208741 18320071
MESH:D001943 Breast Neoplasms Diethylnitrosamine 4.4817474063
MESH:D001943 Breast Neoplasms Indomethacin 4.4817401462
MESH:D001943 Breast Neoplasms Methylnitrosourea 4.4816253758 11306469 14633655
MESH:D001943 Breast Neoplasms Quercetin 4.4818628248
MESH:D001943 Breast Neoplasms Sulindac 4.4816642371
MESH:D001943 Breast Neoplasms Tretinoin 4.4816443354 16166294 16873071
MESH:D016535 Bronchial Hyperreactivity Ozone 3.4519059883 15516495 17626835 18315731 18417511 14754758 16777450
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.2916813970
MESH:D002056 Burns Indomethacin 4.4210459503
MESH:D002100 Cachexia Indomethacin 11.4111239499 16537180 15141370 15625704
MESH:D002100 Cachexia Ozone 11.4116183385
MESH:D002105 Cadmium Poisoning Quercetin 5.2516962696
MESH:D002277 Carcinoma Curcumin 3.6118593918
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.8616168501
MESH:D006528 Carcinoma, Hepatocellular marker/mechanism
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 10.7116705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 10.713084413
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 10.7116328049 19539802 16698587 17055752 21159647 17978847 16935385 16288022 11831363 17173139 16779866 17761372 18691550 10672840 19383236 20514400 19107877 19919837 16681979 18788625 18978308 16878318 16569478 18506893 18056438 19171122 19208518 17138121 17162532 3581430 16502159 19701751 20101231 18393292 20727157 19335982 16830150 20935162 18665156 19519916 20214788 17428255 18971187 3084413 18494052 20524982 20512989 20007298 20432363 19052882 10737359 18210153 19418558 16807293 16540662 19394651 19822196 18785209 20084675
MESH:D006528 Carcinoma, Hepatocellular Indomethacin 10.7116391822
MESH:D006528 Carcinoma, Hepatocellular Quercetin 10.7112508355 19519916
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 10.711917145
MESH:D018827 Carcinoma, Lewis Lung Indomethacin 4.4311053908
MESH:D018276 Carcinoma, Medullary Indomethacin 5.0514736730 18791128 11352223
MESH:D002289 Carcinoma, Non-Small-Cell Lung marker/mechanism 18337602
MESH:D002289 Carcinoma, Non-Small-Cell Lung Curcumin 2.8718414057
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.6717234771
MESH:D002292 Carcinoma, Renal Cell Indomethacin 3.2417341418
MESH:D002294 Carcinoma, Squamous Cell Curcumin 10.1018462866
MESH:D002294 Carcinoma, Squamous Cell decitabine 10.1019215824
MESH:D002294 Carcinoma, Squamous Cell Indomethacin 10.1015482327 12636206
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 10.1016051514 16096774
MESH:D006332 Cardiomegaly Quercetin 3.1619794523
MESH:D002318 Cardiovascular Diseases Hydrogen Peroxide 3.3116936243
MESH:D002386 Cataract Acetaminophen 11.4210977129
MESH:D002386 Cataract Methylnitrosourea 11.4212484553
MESH:D002386 Cataract Tretinoin 11.4217460283
MESH:D002471 Cell Transformation, Neoplastic marker/mechanism 19092804
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 23.776135515
MESH:D002471 Cell Transformation, Neoplastic Azoxymethane 23.7718075178 15705887
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 23.772727394 21159647 17174075 7505956
MESH:D002471 Cell Transformation, Neoplastic Ethylnitrosourea 23.7716003739
MESH:D002471 Cell Transformation, Neoplastic Methylnitronitrosoguanidine 23.772727394
MESH:D002471 Cell Transformation, Neoplastic Methylnitrosourea 23.777505956 2727394
MESH:D016543 Central Nervous System Neoplasms Ethylnitrosourea 5.6817160924
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.2916129372
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 3.4419052882
MESH:D002764 Cholecystitis Indomethacin 4.8711181007
MESH:D002822 Choriocarcinoma Tretinoin 4.8616461808
MESH:D019457 Chromosome Breakage Sodium Selenite 4.4615894690
MESH:D002972 Cleft Palate Tretinoin 2.549407595
MESH:D003092 Colitis Curcumin 20.5418200517 16804969 16782535
MESH:D003092 Colitis Dextran Sulfate 20.5412065299 16375993 18023891 15652231
MESH:D003092 Colitis Selenium 20.5417936198
MESH:D003092 Colitis Tretinoin 20.5417035595
MESH:D003103 Coloboma Curcumin 4.2818809619
MESH:D003110 Colonic Neoplasms marker/mechanism 19132900
MESH:D003110 Colonic Neoplasms Azoxymethane 19.5919056647 16818512 15824018 16293270 12189186 14668109 15705887
MESH:D003110 Colonic Neoplasms Curcumin 19.5916340194 19359593
MESH:D003110 Colonic Neoplasms decitabine 19.5917616700
MESH:D003110 Colonic Neoplasms Etodolac 19.5916004971
MESH:D003110 Colonic Neoplasms Indomethacin 19.5915936596 15625704 15786552 15963497 11260862 15637740
MESH:D003110 Colonic Neoplasms irinotecan 19.5917725105 17287894
MESH:D003110 Colonic Neoplasms Quercetin 19.5919056647 19440933 17191121 17148506 16640504 15741050 11134977
MESH:D003110 Colonic Neoplasms Sulindac 19.5912902858 12458338
MESH:D015179 Colorectal Neoplasms marker/mechanism 18716850 17116713
MESH:D015179 Colorectal Neoplasms Azoxymethane 10.0211076880 10416599
MESH:D015179 Colorectal Neoplasms decitabine 10.0218981723
MESH:D015179 Colorectal Neoplasms Etodolac 10.0211076880
MESH:D015179 Colorectal Neoplasms Indomethacin 10.0211197048 12606626 17054584 18059344
MESH:D015179 Colorectal Neoplasms irinotecan 10.0217454858 18259882 18509181 16391804 16303861 17159606 15273666
MESH:D015179 Colorectal Neoplasms Quercetin 10.0218095365 18852136
MESH:D015179 Colorectal Neoplasms Sulindac 10.0210666051 11197048 18059344 11076880
MESH:D016510 Corneal Neovascularization Curcumin 4.6118497527
MESH:D018352 Coronavirus Infections Indomethacin 5.4217302372
MESH:D019465 Craniofacial Abnormalities Tretinoin 1.819142499 14991402 9211117 9664655 9224671 8800419 16925845 10589399 9125849 17551590
MESH:D003456 Cryptorchidism vinclozolin 4.0614966744
MESH:D003490 Cyanosis 2,6-dinitrotoluene 3.7318551238
MESH:C535944 Desmoid disease, hereditary marker/mechanism
MESH:D003920 Diabetes Mellitus Sodium Selenite 3.5316285004
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 3.5019496084
MESH:D003924 Diabetes Mellitus, Type 2 Curcumin 4.3418403477
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 4.3420387270
MESH:D003928 Diabetic Nephropathies Curcumin 3.7618204486
MESH:D003930 Diabetic Retinopathy Sulindac 4.9012861449 17621415
MESH:D003967 Diarrhea Indomethacin 3.527237001 7907874
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 11.0218551238 21346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 11.0219164858 12540782 10774834 12705907 19420014 16781746 12392966 18071297 18713872 19739265 11743745 10915739 11739529 10663392 15619225 19416960 12958197 14986274 16393943 14725611 15968718 11529661 16109766 14550746 12594235 12153990 16485898 11834606 2444490 17906064 11421492 11461765 16177239 11287661 19370779 16227642 19085960 16081117 17522070 19923254 17562736
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 11.0219107877
MESH:D056486 Drug-Induced Liver Injury Selenium 11.0215131321
MESH:D056486 Drug-Induced Liver Injury Sodium Selenite 11.0215131321
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.8019426721
MESH:D004374 Ductus Arteriosus, Patent Indomethacin 4.8518446180 16326151 17190690 16133044 18043480 12774134
MESH:D004381 Duodenal Ulcer Curcumin 8.4917351913
MESH:D004381 Duodenal Ulcer Indomethacin 8.4917202747 16699067 11595431 17151854 17045617 17329845 11535926 11991626 17351913 11595415 10671773
MESH:D004417 Dyspnea Chlorine 4.3320016425
MESH:D004476 Ectodermal Dysplasia Ethylnitrosourea 5.6818357618
MESH:D004487 Edema Indomethacin 3.2510653021 16100529 7990266 7907874 8985016 19703484 8273558
MESH:D004489 Edema, Cardiac Tretinoin 4.1718230668
MESH:D004701 Endocrine Gland Neoplasms decitabine 4.8219294695
MESH:D016889 Endometrial Neoplasms Tretinoin 2.9216569247
MESH:D004715 Endometriosis Indomethacin 8.7615652904
MESH:D004715 Endometriosis Sulindac 8.7615652904
MESH:D019446 Endotoxemia Indomethacin 4.2118509659
MESH:D004751 Enteritis Indomethacin 4.4510567023 16328016 17763956
MESH:D020345 Enterocolitis, Necrotizing Indomethacin 4.6917980183
MESH:D004802 Eosinophilia Indomethacin 3.7711298111
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.8216302075
MESH:D004938 Esophageal Neoplasms Indomethacin 4.7611005569
MESH:D004938 Esophageal Neoplasms Sulindac 4.7612235107
MESH:D005124 Eye Abnormalities marker/mechanism 16938888
MESH:D005124 Eye Abnormalities Tretinoin 3.3616938888 9664655
MESH:D005234 Fatty Liver Curcumin 7.1619297423
MESH:D005234 Fatty Liver Diethylnitrosamine 7.1621071580 20387270
MESH:D005334 Fever Indomethacin 3.8617627676 11852909 10431976
MESH:D018221 Fibromatosis, Abdominal marker/mechanism 10686957
MESH:D018221 Fibromatosis, Abdominal Sulindac 5.1814745880
MESH:D018222 Fibromatosis, Aggressive marker/mechanism 11816139
MESH:D018222 Fibromatosis, Aggressive Sulindac 4.8419069698
MESH:D005354 Fibrosarcoma Indomethacin 11.2210962813
MESH:D005354 Fibrosarcoma Methylnitrosourea 11.2211555667
MESH:D005355 Fibrosis Curcumin 18.8718705752
MESH:D005355 Fibrosis Indomethacin 18.8717994277
MESH:D005355 Fibrosis Quercetin 18.8719474275
MESH:D005355 Fibrosis Tretinoin 18.8717994277
MESH:D005499 Folliculitis Indomethacin 4.8711298111
MESH:D005739 Gas Poisoning Chlorine 4.7120016425
MESH:D005756 Gastritis Acetaminophen 10.1516983495
MESH:D005756 Gastritis Indomethacin 10.1515046732
MESH:D005764 Gastroesophageal Reflux Sulindac 4.7311910360
MESH:D005770 Gastrointestinal Neoplasms marker/mechanism 21297660
MESH:D005770 Gastrointestinal Neoplasms Curcumin 4.4018462866
MESH:D030342 Genetic Diseases, Inborn vinclozolin 4.6416973722
MESH:D005832 Genital Diseases, Male vinclozolin 5.0016417039
MESH:D005909 Glioblastoma Curcumin 20.2417596214
MESH:D005909 Glioblastoma Ethylnitrosourea 20.2416436596
MESH:D005909 Glioblastoma Indomethacin 20.2412870263
MESH:D005909 Glioblastoma Quercetin 20.2419804834
MESH:D005909 Glioblastoma Tretinoin 20.2417312396
MESH:D005910 Glioma Ethylnitrosourea 13.2318412241 16357521 16651633
MESH:D005910 Glioma Indomethacin 13.2316487511 18371953
MESH:D005910 Glioma Methylnitrosourea 13.239825942
MESH:D005910 Glioma Quercetin 13.2317643826
MESH:D005923 Glomerulosclerosis, Focal Segmental Indomethacin 4.0511849393
MESH:D006073 Gout Indomethacin 5.0511248219
MESH:D006258 Head and Neck Neoplasms Curcumin 16.8618829502 18462866
MESH:D006258 Head and Neck Neoplasms decitabine 16.8619215824
MESH:D006258 Head and Neck Neoplasms Indomethacin 16.8615482327
MESH:D006258 Head and Neck Neoplasms Tretinoin 16.8616096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.8616084493
MESH:D006330 Heart Defects, Congenital Tretinoin 2.749664655 14991402
MESH:D006333 Heart Failure Selenium 2.9017162251
MESH:D006501 Hepatic Encephalopathy Indomethacin 4.3115633222
MESH:D019698 Hepatitis C, Chronic Indomethacin 4.4015135802
MESH:D015417 Hereditary Sensory and Motor Neuropathy Curcumin 4.7517701891
MESH:D006930 Hyperalgesia Acetaminophen 11.7416870215
MESH:D006930 Hyperalgesia Indomethacin 11.7412727271
MESH:D006930 Hyperalgesia Tretinoin 11.7416870215
MESH:D034321 Hyperamylasemia Indomethacin 5.4217883296
MESH:D006937 Hypercholesterolemia Curcumin 3.7918704882
MESH:D006940 Hyperemia Indomethacin 4.7112524144
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.2816778211
MESH:D006943 Hyperglycemia Quercetin 3.7811834736 18262572
MESH:D006949 Hyperlipidemias marker/mechanism 17546600
MESH:D006949 Hyperlipidemias Indomethacin 3.8917546600
MESH:D006973 Hypertension Quercetin 2.7518356687
MESH:D046110 Hypertension, Pregnancy-Induced Hydralazine 4.3416612254
MESH:D007077 Ileal Diseases Indomethacin 4.7210574470 18306037
MESH:D007079 Ileitis Indomethacin 5.0510647630 10651667 16133968
MESH:D007235 Infant, Premature, Diseases Indomethacin 5.0716133044
MESH:D007248 Infertility, Male decitabine 10.2817581917
MESH:D007248 Infertility, Male Methylnitrosourea 10.287193160
MESH:D007248 Infertility, Male vinclozolin 10.2816467254
MESH:D007249 Inflammation Curcumin 10.7918403477 16956363 17151092
MESH:D007249 Inflammation Diethylnitrosamine 10.7918785209
MESH:D007249 Inflammation Indomethacin 10.793291741 7812673 12568917
MESH:D007249 Inflammation Sulindac 10.793291741
MESH:D015212 Inflammatory Bowel Diseases marker/mechanism 18716850
MESH:D015212 Inflammatory Bowel Diseases Curcumin 6.6818596194 18200517
MESH:D015212 Inflammatory Bowel Diseases Dextran Sulfate 6.6815339030 20423518
MESH:D007251 Influenza, Human Quercetin 10.0716624496
MESH:D007251 Influenza, Human Selenium 10.0716624496
MESH:D007333 Insulin Resistance Sodium Selenite 3.0914714311
MESH:D007410 Intestinal Diseases Indomethacin 8.9211686837 10210152 17994277 15610444 11855677 17329856 11713966 18236018 15831440
MESH:D007410 Intestinal Diseases Tretinoin 8.9217994277
MESH:D007414 Intestinal Neoplasms marker/mechanism 19092804
MESH:D007414 Intestinal Neoplasms Curcumin 9.2710783313
MESH:D007414 Intestinal Neoplasms Sulindac 9.2712663524 12584176 10223192 12351151 10213222 12628509
MESH:D007417 Intestinal Polyps Sulindac 4.7111245490 12394442
MESH:D019586 Intracranial Hypertension Indomethacin 5.0715241188
MESH:D007569 Jaw Abnormalities Tretinoin 3.6415992940 17551590
MESH:D007579 Jejunal Diseases Indomethacin 4.7218306037 10574470 16133968
MESH:D007627 Keloid Quercetin 4.6717086741
MESH:D007674 Kidney Diseases Acetaminophen 9.1815629191 12587719
MESH:D007674 Kidney Diseases Indomethacin 9.1817190690
MESH:D007674 Kidney Diseases Quercetin 9.1816962696
MESH:D007676 Kidney Failure, Chronic Hydrogen Peroxide 9.1516518626
MESH:D007676 Kidney Failure, Chronic Selenium 9.1516518626
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 6.9316705839
MESH:D007680 Kidney Neoplasms Ethylnitrosourea 6.9317379185
MESH:D007889 Leiomyoma Curcumin 4.3018555241
MESH:D016773 Leishmaniasis, Cutaneous Indomethacin 3.6711703811 12228301 10320625
MESH:D007938 Leukemia Curcumin 13.7818462866
MESH:D007938 Leukemia decitabine 13.7818980019 19235587
MESH:D007938 Leukemia Quercetin 13.7817468513
MESH:D007938 Leukemia Tretinoin 13.7817143497
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Curcumin 3.9416106398
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Indomethacin 3.7110785260 15631656 16572323
MESH:D007951 Leukemia, Myeloid decitabine 8.6918454857 17236224 19117987
MESH:D007951 Leukemia, Myeloid Tretinoin 8.6916482212 16932348 19285840
MESH:D015470 Leukemia, Myeloid, Acute decitabine 5.8718460780 18206229 18704418 17679729 19387464 19010910
MESH:D015470 Leukemia, Myeloid, Acute Indomethacin 5.8718360721
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 5.8717596541 19850784 16294345
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 5.1618055864
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 2.9616788101 19225113 17506722 16935935 12679006 16331271 17294898 15748426 16823087 17301526 17361223 19029980 19075265 16766008 16891316 16140955 17649720 19035177 9834237 17712046 19642359 17217047 17339181 17368321 17107899
MESH:D015458 Leukemia, T-Cell Curcumin 4.4816106398
MESH:D007964 Leukocytosis Indomethacin 5.0716537180
MESH:D007969 Leukomalacia, Periventricular Indomethacin 5.4217980183
MESH:D007984 Leydig Cell Tumor vinclozolin 4.4416417039
MESH:D017880 Limb Deformities, Congenital Methylnitrosourea 7.7615526292
MESH:D017880 Limb Deformities, Congenital Tretinoin 7.769224671
MESH:D008101 Liver Abscess, Amebic Indomethacin 5.4211479899
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 2.6619638242 18522880 18407596 18665156 20032147
MESH:D008105 Liver Cirrhosis, Biliary Sulindac 4.0412468960
MESH:D008106 Liver Cirrhosis, Experimental Curcumin 4.7318705752 17355460 18006644
MESH:D008106 Liver Cirrhosis, Experimental Indomethacin 4.7318194892
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 4.7312741479
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 4.7318397230 16248980
MESH:D008107 Liver Diseases Acetaminophen 8.7519784758 16610002 12969438 12587719 19014921 11587558 19460945 16611625
MESH:D008107 Liver Diseases Curcumin 8.7516956363
MESH:D008107 Liver Diseases Diethylnitrosamine 8.7517034775
MESH:D008107 Liver Diseases Sulindac 8.7516867024 14986274
MESH:D017114 Liver Failure, Acute Acetaminophen 2.9816871587 17185352
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 6.847678174
MESH:D008113 Liver Neoplasms Diethylnitrosamine 6.8420405173 19812893 18644402 12112319 20492335 12771043 9163691 20137499 18754104 19499222 19256749 20452335 19426721 19638242 21047994 21278145 16942905 19690152 19833225 15885732 10737359 20583210 20101389 20434301 19427195 2422723 19850985 18977376 15175105 2862719 19294768 19254457 19551842 19073162 19996281 19090486 18978307 19255062 18648771 20501860 19642983 20118626 21167192 21071580
MESH:D008113 Liver Neoplasms Quercetin 6.8418980244
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 8.852876784 2876786 6135515
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 8.8517942915 19009564 18253720 18544905 18093689 16267830 3124819 18079962 19126423 19539802 9362446 18775883 19004024 17854601 21159647 18282651 17174075 2563599 18164116 19519916 16842330 18308698
MESH:D008114 Liver Neoplasms, Experimental Quercetin 8.8519519916
MESH:D038061 Lower Extremity Deformities, Congenital Methylnitrosourea 5.1716080182
MESH:D008171 Lung Diseases Ozone 3.188266340 19066396
MESH:D055370 Lung Injury Ozone 3.5620417186
MESH:D008175 Lung Neoplasms marker/mechanism 18337602
MESH:D008175 Lung Neoplasms Azoxymethane 17.0815824018
MESH:D008175 Lung Neoplasms Curcumin 17.0819359593 18462866 16243823
MESH:D008175 Lung Neoplasms Diethylnitrosamine 17.0820512841 20970405 6695378 21163286
MESH:D008175 Lung Neoplasms Ethylnitrosourea 17.0816271038 6695378 16019985 17703301
MESH:D008175 Lung Neoplasms Indomethacin 17.0811053908 11497255 16537180
MESH:D008175 Lung Neoplasms Methylnitrosourea 17.0818062963
MESH:D008175 Lung Neoplasms Ozone 17.088597069 7614698
MESH:D008175 Lung Neoplasms Quercetin 17.0816280456
MESH:D008175 Lung Neoplasms Sulindac 17.0819359593 15713900
MESH:D008175 Lung Neoplasms tipifarnib 17.0816885199
MESH:D008223 Lymphoma Curcumin 16.2518462866
MESH:D008223 Lymphoma decitabine 16.2519470736
MESH:D008223 Lymphoma Ethylnitrosourea 16.2515790496
MESH:D008223 Lymphoma Methylnitrosourea 16.2511418001 16257854
MESH:D016393 Lymphoma, B-Cell Methylnitrosourea 9.5414633661
MESH:D016393 Lymphoma, B-Cell Sodium Selenite 9.5414737004
MESH:D016399 Lymphoma, T-Cell Curcumin 10.7816173963
MESH:D016399 Lymphoma, T-Cell Ethylnitrosourea 10.7815375218
MESH:D008325 Mammary Neoplasms, Experimental Ethylnitrosourea 12.8810767621 10838139 18041768
MESH:D008325 Mammary Neoplasms, Experimental Methylnitrosourea 12.8811807958 14999141 11751437 10838139 19196723 15688392 14633655 16944150 15113128 12931682 17131329 16619500 15313902 10767621 16827153 17020996 16051031
MESH:D008325 Mammary Neoplasms, Experimental Selenium 12.8815318939
MESH:D008325 Mammary Neoplasms, Experimental tipifarnib 12.8816648579
MESH:D008527 Medulloblastoma marker/mechanism
MESH:D008527 Medulloblastoma Tretinoin 2.6717453147
MESH:D008545 Melanoma Curcumin 6.8918462866 17885582
MESH:D008545 Melanoma decitabine 6.8917785578 16505122
MESH:D008545 Melanoma Sulindac 6.8916642371
MESH:D008545 Melanoma Tretinoin 6.8916752155
MESH:D008546 Melanoma, Experimental Acetaminophen 3.2819513568
MESH:D008569 Memory Disorders Curcumin 3.8717263510
MESH:D008579 Meningioma Ethylnitrosourea 5.6817943659
MESH:D008591 Meningomyelocele Tretinoin 4.1416940565
MESH:D008607 Mental Retardation marker/mechanism 8071957
MESH:D008654 Mesothelioma marker/mechanism 17659810
MESH:D008654 Mesothelioma Selenium 2.6715107826
MESH:D008679 Metaplasia Ozone 4.8110496685
MESH:D053842 Microsatellite Instability Methylnitronitrosoguanidine 5.5917671175
MESH:D008881 Migraine Disorders Indomethacin 3.4711903285
OMIM:276300 MISMATCH REPAIR CANCER SYNDROME marker/mechanism
MESH:D009062 Mouth Neoplasms Indomethacin 3.7712636206
MESH:D052016 Mucositis irinotecan 4.7117159606
MESH:D009101 Multiple Myeloma Curcumin 6.8419372569
MESH:D009101 Multiple Myeloma decitabine 6.8418172295
MESH:D009134 Muscular Atrophy, Spinal Curcumin 4.6217962980
MESH:D009190 Myelodysplastic Syndromes decitabine 6.9219010910 16882708 18608210 19157545
MESH:D009190 Myelodysplastic Syndromes Tretinoin 6.9217596541
MESH:D009203 Myocardial Infarction Quercetin 2.8719595682
MESH:D015428 Myocardial Reperfusion Injury Quercetin 3.5719207477
MESH:D009336 Necrosis 2,6-dinitrotoluene 3.577678174 18551238
MESH:D009361 Neoplasm Invasiveness Curcumin 4.0918495463
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 8.933581430 9029167
MESH:D009362 Neoplasm Metastasis Indomethacin 8.9311239499 11053908 16537180
MESH:D009362 Neoplasm Metastasis irinotecan 8.9318259882
MESH:D009369 Neoplasms decitabine 10.7319470736 17925555 19116145
MESH:D009369 Neoplasms Methylnitrosourea 10.7315533788
MESH:D009369 Neoplasms Quercetin 10.7315185748
MESH:D009369 Neoplasms Tretinoin 10.7316946489 16594593
MESH:D009374 Neoplasms, Experimental Ethylnitrosourea 13.8516707424
MESH:D009374 Neoplasms, Experimental Indomethacin 13.8510663608 15625704
MESH:D009374 Neoplasms, Experimental Methylnitrosourea 13.8512696579
MESH:D009376 Neoplasms, Hormone-Dependent Curcumin 4.2312497104
MESH:D009421 Nervous System Malformations Tretinoin 3.509125849
MESH:D009423 Nervous System Neoplasms Curcumin 5.3318462866
MESH:D009436 Neural Tube Defects Tretinoin 2.869142499
MESH:D009442 Neurilemmoma Ethylnitrosourea 12.3017160924 16651423 16003739
MESH:D009442 Neurilemmoma Methylnitrosourea 12.3011555667
MESH:D009447 Neuroblastoma irinotecan 3.338761367
MESH:D019636 Neurodegenerative Diseases Acetaminophen 18.1718514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 18.1720387270
MESH:D019636 Neurodegenerative Diseases Indomethacin 18.1712349958
MESH:D019636 Neurodegenerative Diseases Sulindac 18.1717266991 16850258
MESH:D017599 Neuroectodermal Tumors irinotecan 4.438761367
MESH:D020078 Neurogenic Inflammation Quercetin 4.0917929310
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.8220387270
MESH:D009765 Obesity Curcumin 2.6719297423
MESH:D007752 Obstetric Labor, Premature Indomethacin 4.876374098
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 3.1816049721
MESH:D009837 Oligodendroglioma Ethylnitrosourea 5.6817160924
MESH:D010003 Osteoarthritis Indomethacin 3.497009135
MESH:D010024 Osteoporosis Curcumin 3.2918719352
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 3.9519495926
MESH:D010051 Ovarian Neoplasms Curcumin 10.5418462866 19020741
MESH:D010051 Ovarian Neoplasms decitabine 10.5419259094 19331143
MESH:D010051 Ovarian Neoplasms Quercetin 10.5419005980
MESH:D010051 Ovarian Neoplasms Tretinoin 10.5416936753
MESH:D010146 Pain Acetaminophen 14.2016870215
MESH:D010146 Pain Indomethacin 14.2013679232 17627676 3291741 17440234
MESH:D010146 Pain Sulindac 14.203291741
MESH:D010146 Pain Tretinoin 14.2016870215
MESH:D010149 Pain, Postoperative Indomethacin 4.3818702446 12538197
MESH:D010190 Pancreatic Neoplasms Curcumin 23.1919196508 17440100 19401701
MESH:D010190 Pancreatic Neoplasms decitabine 23.1919294695
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 23.1916540662
MESH:D010190 Pancreatic Neoplasms Methylnitrosourea 23.1916965848
MESH:D010190 Pancreatic Neoplasms Quercetin 23.1916965848
MESH:D010190 Pancreatic Neoplasms Sulindac 23.1911504793 16820089
MESH:D010190 Pancreatic Neoplasms Tretinoin 23.1915976015
MESH:D010195 Pancreatitis Indomethacin 3.6517883296 15028970
MESH:D010212 Papilloma Hydrogen Peroxide 3.8012065085
MESH:D010257 Paraneoplastic Syndromes Indomethacin 5.4216537180
MESH:D020734 Parkinsonian Disorders Indomethacin 3.8612349958
MESH:D051302 Paroxysmal Hemicrania Indomethacin 5.4211903285
MESH:D010437 Peptic Ulcer Indomethacin 4.8511148446
MESH:D010518 Periodontitis Indomethacin 4.6117225004
MESH:D010538 Peritonitis Ozone 3.8416369182
MESH:D010787 Photosensitivity Disorders 4-hydroxy-2-nonenal 5.2011550810
MESH:D010954 Plasmacytoma Selenium 4.5915087411
MESH:D011014 Pneumonia Ozone 4.1018381685 18007984 18929643
MESH:D011230 Precancerous Conditions Azoxymethane 14.2119056647 12458338 14668109
MESH:D011230 Precancerous Conditions Diethylnitrosamine 14.212563599
MESH:D011230 Precancerous Conditions Quercetin 14.2119056647
MESH:D047928 Premature Birth Indomethacin 4.8417000239
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 3.6018220299 18042343 19015723
MESH:D055728 Primary Myelofibrosis decitabine 4.4417616702
MESH:D011469 Prostatic Diseases vinclozolin 4.6418220299
MESH:D011471 Prostatic Neoplasms marker/mechanism 17363566
MESH:D011471 Prostatic Neoplasms Clorgyline 1.9319691856
MESH:D011471 Prostatic Neoplasms Curcumin 1.9311398177 10851300 18156803 15129424 18226269 18769126 12497104
MESH:D011471 Prostatic Neoplasms Methylnitrosourea 1.9312376480 15682402
MESH:D011471 Prostatic Neoplasms Quercetin 1.9314715546 17292933
MESH:D011471 Prostatic Neoplasms Sodium Selenite 1.9318760546
MESH:D011472 Prostatitis vinclozolin 4.6418629315
MESH:D011507 Proteinuria Indomethacin 8.4311849393
MESH:D011507 Proteinuria Tretinoin 8.4316636307
MESH:D011625 Pterygium Tretinoin 4.5016723453
MESH:D011656 Pulmonary Emphysema Curcumin 4.2719168576
MESH:D012004 Rectal Neoplasms marker/mechanism 8071957 11766074
MESH:D012120 Respiration Disorders Chlorine 4.9118579056
MESH:D012128 Respiratory Distress Syndrome, Adult Curcumin 3.7610666014 18379247
MESH:D012162 Retinal Degeneration Methylnitrosourea 4.1918172121 18155124
MESH:D012175 Retinoblastoma Methylnitrosourea 5.1911555667
MESH:D012208 Rhabdomyosarcoma decitabine 10.0419155313
MESH:D012208 Rhabdomyosarcoma Tretinoin 10.0416116481 16283617
MESH:D012509 Sarcoma Curcumin 3.8618462866
MESH:D012554 Schistosomiasis japonica Quercetin 5.2516862918
MESH:D012640 Seizures 2,6-dinitrotoluene 2.3418551238
MESH:D018805 Sepsis Curcumin 3.8418389075
MESH:D012878 Skin Neoplasms Hydrogen Peroxide 5.4712065085
MESH:D012878 Skin Neoplasms Tretinoin 5.4716467112
MESH:D013272 Stomach Diseases Indomethacin 4.1216280098 18209964 15472012 18545984 15038085 16113693 16184426 17638125 10215738 10192188 17207306 17160473 10486359
MESH:D013274 Stomach Neoplasms marker/mechanism
MESH:D013274 Stomach Neoplasms decitabine 7.8819037991
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 7.8818456281
MESH:D013274 Stomach Neoplasms Indomethacin 7.8815609394
MESH:D013274 Stomach Neoplasms irinotecan 7.8815723263
MESH:D013274 Stomach Neoplasms Methylnitrosourea 7.8815930296 16257854 18593901
MESH:D013274 Stomach Neoplasms Tretinoin 7.8817261132
MESH:D013276 Stomach Ulcer Curcumin 6.7119188055 16631530
MESH:D013276 Stomach Ulcer Indomethacin 6.7110750652 12467913 16755016 17895592 18431645 17918041 10423059 12498302 18543354 17654042 1323529 17977527 17135157 14567935 17627676 16934674 10878458 12787963 16150113 18726076 18237397 18181030 18299717 11595431 18087811 16631530 15138204 18193104 11595415 18209962 16397915 17657623 11523592 16169175 15104355 11906479 11729361 16252198 12077510 15255614 12500499 11145282
MESH:D013953 Thymus Neoplasms Ethylnitrosourea 11.3115790496
MESH:D013953 Thymus Neoplasms Methylnitrosourea 11.3111418001
MESH:D013964 Thyroid Neoplasms decitabine 20.1417967635
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 20.147505956
MESH:D013964 Thyroid Neoplasms Indomethacin 20.1411352223 14736730 18791128
MESH:D013964 Thyroid Neoplasms Methylnitrosourea 20.147505956 3078959
MESH:D013964 Thyroid Neoplasms Tretinoin 20.1416026305 17045167
MESH:D014062 Tongue Neoplasms Tretinoin 3.5316051514
MESH:D014376 Tuberculosis Tretinoin 3.0516040207
MESH:D014456 Ulcer Indomethacin 4.6017380554 10574470
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 11.0016049721
MESH:D001749 Urinary Bladder Neoplasms Curcumin 11.0018593936
MESH:D001749 Urinary Bladder Neoplasms decitabine 11.0017616700 19087683
MESH:D001749 Urinary Bladder Neoplasms Quercetin 11.0016720314
MESH:D014565 Urogenital Neoplasms Curcumin 4.9718462866
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 4.0210091137
MESH:D014581 Urticaria Acetaminophen 2.7110982225
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 3.4216129372
MESH:D014594 Uterine Neoplasms Sulindac 4.3218645019
MESH:D014604 Uveal Neoplasms decitabine 11.8317785578
MESH:D014604 Uveal Neoplasms Tretinoin 11.8316752155
MESH:D014820 Vitiligo Tretinoin 3.7816761959
MESH:D014839 Vomiting Indomethacin 4.4511897121
MESH:D009396 Wilms Tumor Tretinoin 3.7216287080
Pathway ID Pathway Name
REACT:578 Apoptosis
KEGG:05217 Basal cell carcinoma
KEGG:05210 Colorectal cancer
KEGG:05213 Endometrial cancer
KEGG:05200 Pathways in cancer
KEGG:04810 Regulation of actin cytoskeleton
REACT:11045 Signaling by Wnt
KEGG:04310 Wnt signaling pathway
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA24875
    • No data
    Releated disease ID Related disease Name
    PA443265Adenocarcinoma
    PA445084Wilms Tumor
    PA443756Colonic Neoplasms
    PA443560Breast Neoplasms
    PA445204Ovarian Neoplasms
    Releated drug ID Related drug Name
    PA128406956fluorouracil
    PA450198leucovorin
    PA450205levamisole
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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