AutismKB 2.0

Annotation Detail for HPX


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Basic Information Top
Gene Symbol:HPX ( FLJ56652,HX )
Gene Full Name: hemopexin
Band: 11p15.4
Quick LinksEntrez ID:3263; OMIM: 142290; Uniprot ID:HEMO_HUMAN; ENSEMBL ID: ENSG00000110169; HGNC ID: 5171
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
Desease IDDesease Name
2107Proteinuria
2203Nephrosis
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of HPX mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of HPX mRNAaffects expression 17562736
D000082 Acetaminophen Acetaminophen affects the expression of HPX proteinaffects expression 16099942
D000082 Acetaminophen Acetaminophen results in increased expression of HPX proteinincreases expression 16687475
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of HPX proteinaffects expression 20106945
C061621 alpha-naphthyl isocyanate alpha-naphthyl isocyanate affects the expression of HPX proteinaffects expression 16099942
D000643 Ammonium Chloride Ammonium Chloride affects the expression of HPX mRNAaffects expression 16483693
C432165 anthra(1,9-cd)pyrazol-6(2H)-one anthra(1,9-cd)pyrazol-6(2H)-one inhibits the reaction [Ozone results in increased expression of HPX mRNA]decreases reaction|increases expression 17460151
D019324 beta-Naphthoflavone beta-Naphthoflavone results in decreased expression of HPX mRNAdecreases expression 19737606
C053342 brevetoxin brevetoxin analog results in decreased expression of HPX mRNAdecreases expression 14529743
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of HPX mRNAaffects expression 17484886
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of HPX mRNAincreases expression 16239168
D016572 Cyclosporine Cyclosporine results in decreased expression of HPX mRNAdecreases expression 20106945
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of HPX mRNAaffects expression 17555576
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of HPX mRNAaffects cotreatment|increases expression 17942748
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of HPX mRNAdecreases expression 16940010
17108234
D005472 Fluorouracil TP53 protein affects the reaction [Fluorouracil results in decreased expression of HPX mRNA]affects reaction|decreases expression 15016801
C056933 fumonisin B1 fumonisin B1 results in increased expression of HPX mRNAincreases expression 16221962
C029424 hydrazine hydrazine results in increased expression of HPX mRNAincreases expression 15282401
D010126 Ozone anthra(1,9-cd)pyrazol-6(2H)-one inhibits the reaction [Ozone results in increased expression of HPX mRNA]decreases reaction|increases expression 17460151
D010126 Ozone Ozone results in increased expression of HPX mRNAincreases expression 17460151
C006253 pirinixic acid pirinixic acid results in decreased expression of HPX mRNAdecreases expression 16221962
C006253 pirinixic acid pirinixic acid affects the expression of HPX proteinaffects expression 16099942
C006253 pirinixic acid pirinixic acid results in decreased expression of HPX mRNAdecreases expression 16940010
C017947 sodium arsenite sodium arsenite affects the expression of HPX mRNAaffects expression 17450228
D013629 Tamoxifen Tamoxifen affects the expression of HPX mRNAaffects expression 17555576
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of HPX mRNAaffects cotreatment|increases expression 17942748
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.4914745880
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.7915322242 14514962 11752688
MESH:D000138 Acidosis Ammonium Chloride 3.5018287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.8917505938
MESH:D055371 Acute Lung Injury pirinixic acid 3.0518653653
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 4.2814692618
MESH:D000230 Adenocarcinoma Fluorouracil 4.2817638652
MESH:D000236 Adenoma beta-Naphthoflavone 3.2919389873
MESH:D018248 Adenoma, Liver Cell pirinixic acid 9.7016434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 9.7016835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.6415276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.8517306315 16712894
MESH:D000544 Alzheimer Disease Ozone 2.4215513908
MESH:D000740 Anemia Fluorouracil 8.4817963324 15504547 16511603
MESH:D000740 Anemia Tetrachlorodibenzodioxin 8.4811748828
MESH:D000799 Angioedema Acetaminophen 3.7910982225
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.4011256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.6215885639
MESH:D001172 Arthritis, Rheumatoid Ozone 2.5415570426
MESH:D001249 Asthma Ozone 2.6217854713 16373670
MESH:D001321 Autistic Disorder Acetaminophen 1.4218445737
MESH:D001778 Blood Coagulation Disorders pirinixic acid 8.5619483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 8.5612125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.7315340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.7215746008
MESH:D001943 Breast Neoplasms Fluorouracil 1.8615136595 18608205 19217205 16110121 18357371 16595493 16557594
MESH:D001943 Breast Neoplasms Tamoxifen 1.8617440819 19011961 18984771 17893378 20065188 19221464 17049068 18855134 19289846 18815881 21152245 18351453 19288272 19142967 17242785 19115204 19244106 19189210 20859285 18629630 16818667 15668708 19410462 19189212 21138602 16202921 20390343 19084267 19487384 15565566 20544844 11161223 17261762 19155303 19103187 20135344 19200415 16273361 18997820 20005174 16873071 18425577 19059307 19066611 18821012
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.8620435547
MESH:D016535 Bronchial Hyperreactivity Ozone 3.6219059883 16777450 18315731 14754758 15516495 17626835 18417511
MESH:D002100 Cachexia Ozone 4.6816183385
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.7216227642 16097048 15673190 16124888 15700767 3786805 15721981 18705752 16011737 16050911 10355542 16192424
MESH:D002276 Carcinoid Tumor Fluorouracil 4.6116051944
MESH:D002277 Carcinoma Fluorouracil 8.0017121937
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 8.0016835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.4419066611
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 16.7816705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 16.783084413
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 16.7821507988 12907637 12619106
MESH:D006528 Carcinoma, Hepatocellular anthra(1,9-cd)pyrazol-6(2H)-one 16.7819418558
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 16.7818788625
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 16.7817045692 17971768 17088986 16799960 16332177 18930000
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 16.7817306315 15276417 16507464
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 16.7816924424
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 2.9918695887
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 4.7016280240 16757204 18986760 17066447
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 4.7018572023
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.5517572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3318850075 18670907 16120746
MESH:D002386 Cataract Acetaminophen 2.5410977129
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 6.5012371664
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 6.5019524636 20056578
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.1016835633
MESH:D002779 Cholestasis Cyclosporine 13.0519486331
MESH:D002779 Cholestasis Ethinyl Estradiol 13.0517681005 17333356 16105132 17110522 16919318 11677210 15861022
MESH:D002779 Cholestasis pirinixic acid 13.0519176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.0812621046 8697196 16354765 15340226 15668235
MESH:D003110 Colonic Neoplasms Fluorouracil 2.2215001691 17287894 16510598 17169374 17725105 16340194 18772588 17016597 17018589 17172411
MESH:D015179 Colorectal Neoplasms Fluorouracil 2.0014970324 18802399 16391804 16524972 17016601 16331619 15289873 16282729 17094418 17401013 17594712 16303861 17255274 18383874 18288408 18509181 18949393 15148649 18448328 17695437 17454858 20501625
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.0014669216 17141729
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 1.2510048152 15322242 20055451
MESH:D003490 Cyanosis 2,4-dinitrotoluene 3.9518551238
MESH:D007644 Darier Disease Fluorouracil 4.7316733453
MESH:D003711 Demyelinating Diseases Tamoxifen 4.3019031437
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3918249437
MESH:D003924 Diabetes Mellitus, Type 2 marker/mechanism 16506275
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.6517107852
MESH:D003928 Diabetic Nephropathies Tamoxifen 3.4219279558
MESH:D056486 Drug-Induced Liver Injury marker/mechanism 16099942
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 11.8118551238 21346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 11.8112392966 10915739 12594235 11461765 19164858 19085960 2444490 15968718 17562736 19416960 11529661 11421492 10774834 16781746 19370779 12705907 14550746 17906064 16393943 18071297 16485898 17522070 10663392 11287661 11739529 19739265 19923254 16177239 19420014 14725611 11743745 11834606 12153990 15619225 18713872 14986274 12540782 12958197 16227642 16109766 16081117
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 11.8111566570 10915739 15027814 19085960 3732212 17522070 6623471 4309450 15998439 15968718 6884620 2869522 7179309 7440962 3786805 16177239 7120509 9327722 10092053 21278145 19336974 16227642
MESH:D056486 Drug-Induced Liver Injury fumonisin B1 11.8116221962
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 11.8120420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.0419426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.7111462148
MESH:D004487 Edema pirinixic acid 6.3312083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 6.3311000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.8516714409 15322242 18230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 8.7312538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 8.7319031437
MESH:D016889 Endometrial Neoplasms Tamoxifen 3.0017893378 16202921 20544844 19155303
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.9610568697 9294722
MESH:D004938 Esophageal Neoplasms Fluorouracil 2.4317638652 16337965 16481741 15173087 16785472
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.9611564622
MESH:D005234 Fatty Liver Carbon Tetrachloride 23.9815959796 16045604 12631006 19224547 12795759 16239168 61145 17595544
MESH:D005234 Fatty Liver Cyclosporine 23.9819224547
MESH:D005234 Fatty Liver Ethinyl Estradiol 23.9815345470
MESH:D005234 Fatty Liver pirinixic acid 23.9820131406 19236843
MESH:D005234 Fatty Liver Tamoxifen 23.9814986274 19224547
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.1916709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.3911858732
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.4714745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.1219069698
MESH:D005355 Fibrosis Carbon Tetrachloride 14.3518705752
MESH:D005355 Fibrosis Cyclosporine 14.3512639820 12168785
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 14.3520067830
MESH:D005756 Gastritis Acetaminophen 3.6216983495
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.6216452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.168708960
MESH:D005910 Glioma Fluorouracil 2.8416145905
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.5410696789
MESH:D006258 Head and Neck Neoplasms Fluorouracil 3.3415102660 15162350 18337622
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.3011294989 10048152
MESH:D006333 Heart Failure pirinixic acid 2.5020558911
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.3615720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.2711000095
MESH:D006505 Hepatitis Carbon Tetrachloride 3.5319900420 19110552
MESH:D006529 Hepatomegaly fumonisin B1 14.1216221962
MESH:D006529 Hepatomegaly pirinixic acid 14.1216221962 19772884 19176532 18467677
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 14.1215340226 12621046 16120746
MESH:D006689 Hodgkin Disease sodium arsenite 3.1012676792
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.9916354765 15340226 18606429 8697196 16959395
MESH:D006930 Hyperalgesia Acetaminophen 2.6516870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.4716899240
MESH:D006943 Hyperglycemia pirinixic acid 3.1220558911
MESH:D006973 Hypertension Cyclosporine 4.8610903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 4.8618670907 18850075
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.0215338365
MESH:D007021 Hypospadias Ethinyl Estradiol 3.7516945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.4012013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 6.4917937319
MESH:D007248 Infertility, Male sodium arsenite 6.4912646999 15346721
MESH:D007249 Inflammation Tamoxifen 4.7719457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 4.7712878042 12200463
MESH:D007333 Insulin Resistance pirinixic acid 2.5916306350
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.2716580747
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.3915604871
MESH:D007674 Kidney Diseases Acetaminophen 9.7812587719 15629191
MESH:D007674 Kidney Diseases Cyclosporine 9.7818776723 10903974 8314463
MESH:D007674 Kidney Diseases sodium arsenite 9.7820008137
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 17.3016705839
MESH:D007680 Kidney Neoplasms Cyclosporine 17.3012371664
MESH:D007680 Kidney Neoplasms Fluorouracil 17.3016985049
MESH:D007680 Kidney Neoplasms Tamoxifen 17.3018625569
MESH:D007948 Leukemia, Monocytic, Acute anthra(1,9-cd)pyrazol-6(2H)-one 5.3116972261
MESH:D008064 Lipidoses Tamoxifen 3.1117567588 15342952
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 2.7716943688 17157831 11408273 21278145 17334410 17174718 16221502 16239168 11903743
MESH:D008106 Liver Cirrhosis, Experimental alpha-naphthyl isocyanate 6.6816015684
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 6.6812649538 15876570 17714472 15052691 18210741 15996030 17922224 12958196 12666154 17525996 17708605 15959796 14748882 14724832 17761835 18263696 18429990 16027843 18054572 12586293 15931870 18156304 18006644 12741479 12546737 20821823 18251166 16011737 15925388 17640975 17698563 12667390 15338365 10355542 12898905 11481614 12445418 12445421 15673190 17766677 18277467 18418968 17869086 17721639 18395914 17976157 14512876 13678700 15818738 15123356 17823541 16116963 16638106 18187930 16248980 18317297 14620537 18339082 18412020 15362042 17805973 17565644 17557913 17631135 12632514 16192424 18472332 12632512 16015684 15893842 18472094 18205269 14716496 18279442 17481882 15650968 18376398 16097048 15730626 18395095 15370692 15057751 12389079 14716833 16136751 18481824 18166357 18420326 17900296 12609069 16033810 18705752 17944888
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 6.6815474484
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 6.6818564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 6.6812878042
MESH:D008107 Liver Diseases Acetaminophen 3.8419460945 12587719 19014921 16610002 19784758 11587558 12969438 16611625
MESH:D008107 Liver Diseases Carbon Tetrachloride 3.8417285989 16964402 15720792 15830285 16246199
MESH:D017093 Liver Failure Carbon Tetrachloride 4.1015123358
MESH:D017114 Liver Failure, Acute Acetaminophen 9.2116871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 9.2116899240 14706259
MESH:D008113 Liver Neoplasms Aflatoxin B1 25.572125692 15890375 9163691 18177683
MESH:D008113 Liver Neoplasms beta-Naphthoflavone 25.5721295105 19389873
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 25.5719294768
MESH:D008113 Liver Neoplasms Fluorouracil 25.5716603448 17045692 15113037 18383874
MESH:D008113 Liver Neoplasms pirinixic acid 25.5720007298 15890375 16377806
MESH:D008113 Liver Neoplasms sodium arsenite 25.5716712894 15276417
MESH:D008113 Liver Neoplasms Tamoxifen 25.5716684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 25.5716984957
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 13.798603461
MESH:D008114 Liver Neoplasms, Experimental beta-Naphthoflavone 13.7918164116
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 13.7912014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 13.7912151625
MESH:D008171 Lung Diseases Ozone 7.3719066396 8266340
MESH:D008171 Lung Diseases sodium arsenite 7.3719095001
MESH:D055370 Lung Injury Ozone 3.7820417186
MESH:D008175 Lung Neoplasms Aflatoxin B1 8.4614755239
MESH:D008175 Lung Neoplasms Fluorouracil 8.4615246190
MESH:D008175 Lung Neoplasms Ozone 8.467614698 8597069
MESH:D008175 Lung Neoplasms sodium arsenite 8.4617306315 15276417 16712894 17077188 19931552
MESH:D008175 Lung Neoplasms Tamoxifen 8.4618625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 8.4619555203 11884234
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.7315086387
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.7019428831
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 2.5811731420 16827153 14580682 19196723 19196722
MESH:D020149 Manganese Poisoning Tamoxifen 4.4919453300
MESH:D008545 Melanoma sodium arsenite 3.2819082730 16487513
MESH:D008545 Melanoma Tamoxifen 3.2812393984 19393235
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.1215990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.5019513568
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.7316801185
MESH:D008679 Metaplasia Ozone 5.0510496685
MESH:D009062 Mouth Neoplasms Fluorouracil 3.5816757204 18986760
MESH:D009135 Muscular Diseases pirinixic acid 3.4416239165
MESH:D009203 Myocardial Infarction pirinixic acid 2.1119151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.9612213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.8916411023
MESH:D009336 Necrosis 2,4-dinitrotoluene 3.8018551238
MESH:D009362 Neoplasm Metastasis Tamoxifen 2.5219393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.4919410462
MESH:D009369 Neoplasms Fluorouracil 8.0718600527 18239605 16928823
MESH:D009369 Neoplasms pirinixic acid 8.0717405874
MESH:D009369 Neoplasms sodium arsenite 8.0711559025
MESH:D009374 Neoplasms, Experimental sodium arsenite 3.6020056578
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.9419196722 19189210 19200415
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.3917954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.2319348381 18481113
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.1514600291
MESH:D009436 Neural Tube Defects sodium arsenite 3.1012854658
MESH:D019636 Neurodegenerative Diseases Acetaminophen 2.8118514411
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.3916436463
MESH:D009765 Obesity pirinixic acid 1.8020558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 3.3712819281 16049721
MESH:D010051 Ovarian Neoplasms sodium arsenite 2.4117306315 15276417
MESH:D010146 Pain Acetaminophen 2.3416870215
MESH:D010190 Pancreatic Neoplasms Fluorouracil 2.6416500647 16929163 19003803 15113037
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.6211578682
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.1912520081
MESH:D010538 Peritonitis Ozone 4.0716369182
MESH:D011014 Pneumonia Ozone 4.3318007984 18929643 18381685
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.4918163543
MESH:D011230 Precancerous Conditions Cyclosporine 3.1612371664
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.1311896295 11118676 11222880 11399792
MESH:D011471 Prostatic Neoplasms Fluorouracil 2.6119082440 18626508
MESH:D011471 Prostatic Neoplasms sodium arsenite 2.6116039940
MESH:D011471 Prostatic Neoplasms Tamoxifen 2.6115067354
MESH:D011537 Pruritus Ethinyl Estradiol 3.2515861022 16919318
MESH:D011565 Psoriasis Cyclosporine 2.2116882103
MESH:D012004 Rectal Neoplasms Fluorouracil 3.9515538739 18722050 16160472 18286688
MESH:D015427 Reperfusion Injury pirinixic acid 2.3519058328
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.7718990726
MESH:D012640 Seizures 2,4-dinitrotoluene 2.4918551238
MESH:D012878 Skin Neoplasms sodium arsenite 5.4919524636 18572023
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.4916192470
MESH:D013088 Spermatocele Ethinyl Estradiol 11.3716709447
MESH:D013088 Spermatocele Tamoxifen 11.3716709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.9819457130
MESH:D016135 Spinal Dysraphism sodium arsenite 3.7412854658
MESH:D013274 Stomach Neoplasms Fluorouracil 2.0018396642 15786421 17522103 16951190 16424979 17172411 18567086 17498489 19084572 19015929
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.5611994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.0915669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.8512697716
MESH:D014062 Tongue Neoplasms Fluorouracil 3.9316280240
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 8.1716049721
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 8.1711723127 16712894 16452187 17306315
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 8.1717572228 16712894 8653321
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 4.2510091137
MESH:D014581 Urticaria Acetaminophen 2.9110982225
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 9.2816803524
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 9.2811813266
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.2314692618
MESH:D014605 Uveitis Cyclosporine 3.931336536
MESH:D014652 Vascular Diseases sodium arsenite 4.3617056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.5412125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.4814671159 15869587
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.1915886252
MESH:D014985 Xerophthalmia Cyclosporine 4.3917120751
No data
Pharmacogenomics Knowledge Base Top
Drug Bank Top
Drugbank ID Action Drug Name Description
DB03014 - Heme
No data
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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