AutismKB 2.0

Annotation Detail for APEX1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:APEX1 ( APE,APE1,APEN,APEX,APX,HAP1,REF1 )
Gene Full Name: APEX nuclease (multifunctional DNA repair enzyme) 1
Band: 14q11.2
Quick LinksEntrez ID:328; OMIM: 107748; Uniprot ID:APEX1_HUMAN; ENSEMBL ID: ENSG00000100823; HGNC ID: 587
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa03410Base excision repair
Pathway IDPathway Name
DNA Repair
Pathway IDPathway Name
200030HIF-2-alpha transcription factor network
No data
Pathway IDPathway Name
500945Removal of DNA patch containing abasic residue
500033Resolution of AP sites via the multiple-nucleotide patch replacement pathway
501000Displacement of DNA glycosylase by APE1
500984Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1802Cockayne syndrome
1934Cancer
1954Stroke
2134Amyotrophic lateral sclerosis
Desease Name
prostate cancer
melanoma
DNA repair
CANCER
radiotherapy response
radiotherapy
lung cancer
radiotherapy sensitivity
upper aerodigestive tract cancer
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of APEX1 mRNAaffects expression 21346803
C019499 2-nitrofluorene 2-nitrofluorene results in increased expression of APEX1 mRNAincreases expression 15890375
C016617 2-nitropropane 2-nitropropane results in increased expression of APEX1 mRNAincreases expression 19268524
C016617 2-nitropropane 2-nitropropane results in increased expression of APEX1 proteinincreases expression 19268524
C016617 2-nitropropane APEX1 protein affects the susceptibility to 2-nitropropaneaffects response to substance 19268524
C016617 2-nitropropane APEX1 protein inhibits the reaction [2-nitropropane results in increased activity of CASP3 protein]decreases reaction|increases activity 19268524
C016617 2-nitropropane APEX1 protein inhibits the reaction [2-nitropropane results in increased expression of GADD45G mRNA]decreases reaction|increases expression 19268524
C016617 2-nitropropane APEX1 protein inhibits the reaction [2-nitropropane results in increased expression of TRP53 protein]decreases reaction|increases expression 19268524
C016583 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of APEX1 mRNAincreases expression 15890375
C067134 8-oxo-7-hydrodeoxyguanosine APEX1 gene SNP affects the abundance of 8-oxo-7-hydrodeoxyguanosineaffects abundance 19896490
D000082 Acetaminophen Acetaminophen results in increased expression of APEX1 mRNAincreases expression 16751229
D016604 Aflatoxin B1 Aflatoxin B1 results in decreased expression of APEX1 mRNAdecreases expression 15890375
D000643 Ammonium Chloride Ammonium Chloride affects the expression of APEX1 mRNAaffects expression 16483693
D001151 Arsenic APEX1 protein affects the susceptibility to Arsenicaffects response to substance 18053222
C015001 arsenite arsenite affects the expression of APEX1 mRNAaffects expression 18252256
C015001 arsenite arsenite results in increased expression of APEX1 mRNAincreases expression 15996700
C015001 arsenite arsenite results in increased expression of APEX1 proteinincreases expression 18252256
D016227 Benzoquinones APEX1 protein results in increased reduction of and results in increased susceptibility to Benzoquinonesincreases reduction|increases response to substance 10190555
D001629 Bezafibrate Bezafibrate results in increased expression of APEX1 mRNAincreases expression 15447978
C005961 bis(tri-n-butyltin)oxide bis(tri-n-butyltin)oxide results in increased expression of APEX1 mRNAincreases expression 17553608
D002087 Butyrates Butyrates results in decreased expression of APEX1 mRNAdecreases expression 14674679
D002104 Cadmium Cadmium results in decreased activity of APEX1 proteindecreases activity 16677676
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of APEX1 mRNAincreases expression 17522070
D002330 Carmustine APEX1 protein mutant form results in increased susceptibility to Carmustineincreases response to substance 17259346
D002713 Chlorine [Ozone co-treated with Chlorine] results in decreased expression of APEX1 mRNAaffects cotreatment|decreases expression 18636392
D002725 Chloroform Chloroform results in increased expression of APEX1 mRNAincreases expression 17522070
D002994 Clofibrate Clofibrate results in decreased expression of APEX1 mRNAdecreases expression 17522070
D002995 Clofibric Acid [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of APEX1 mRNAaffects cotreatment|affects expression 17602206
C057862 cyanoginosin LR cyanoginosin LR results in increased expression of APEX1 mRNAincreases expression 17654400
D003520 Cyclophosphamide Cyclophosphamide results in increased expression of APEX1 mRNAincreases expression 11599041
D003606 Dacarbazine APEX1 protein results in decreased susceptibility to Dacarbazinedecreases response to substance 16373707
D003630 Daunorubicin APEX1 protein results in increased reduction of and results in increased susceptibility to Daunorubicinincreases reduction|increases response to substance 10190555
D016047 Zalcitabine APEX1 protein mutant form results in increased susceptibility to Zalcitabineincreases response to substance 17259346
D002945 Cisplatin APEX1 protein results in decreased susceptibility to Cisplatindecreases response to substance 16373707
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of APEX1 mRNAaffects cotreatment|affects expression 17602206
D004052 Diethylnitrosamine Diethylnitrosamine results in decreased expression of APEX1 mRNAdecreases expression 11323195
D004052 Diethylnitrosamine [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of APEX1 mRNAaffects cotreatment|increases expression 18775883
18253720
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of APEX1 mRNAincreases expression 15890375
D004128 Dimethylnitrosamine Dimethylnitrosamine results in increased expression of APEX1 mRNAincreases expression 15890375
D004918 Erythromycin Estolate Erythromycin Estolate results in decreased expression of APEX1 mRNAdecreases expression 17522070
D004958 Estradiol Estradiol results in increased expression of APEX1 mRNAincreases expression 17522070
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of APEX1 mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of APEX1 mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of APEX1 mRNAaffects cotreatment|increases expression 17942748
C036216 ethylene ethylene results in increased expression of APEX1 proteinincreases expression 16051529
D005027 Ethylene Oxide Ethylene Oxide results in increased expression of APEX1 proteinincreases expression 16051529
D011345 Fenofibrate [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of APEX1 mRNAaffects cotreatment|increases expression 18253720
18775883
D011345 Fenofibrate Fenofibrate results in increased expression of APEX1 mRNAincreases expression 18775883
D006861 Hydrogen Peroxide APEX1 protein mutant form results in increased susceptibility to Hydrogen Peroxideincreases response to substance 17259346
D007608 Kainic Acid [Raloxifene co-treated with Kainic Acid] results in increased expression of APEX1 mRNAaffects cotreatment|increases expression 16120186
D007854 Lead Lead results in decreased activity of APEX1 proteindecreases activity 17013835
D007854 Lead APEX1 protein inhibits the reaction [Lead results in decreased activity of APEX1 protein]decreases activity|decreases reaction 17013835
D008701 Methapyrilene Methapyrilene results in increased expression of APEX1 mRNAincreases expression 15890375
D008741 Methyl Methanesulfonate APEX1 protein mutant form results in increased susceptibility to Methyl Methanesulfonateincreases response to substance 17259346
D016685 Mitomycin APEX1 protein results in increased reduction of and results in increased susceptibility to Mitomycinincreases reduction|increases response to substance 10190555
D009270 Naloxone Naloxone results in decreased expression of APEX1 mRNAdecreases expression 17522070
D015058 1-Naphthylisothiocyanate 1-Naphthylisothiocyanate results in increased expression of APEX1 mRNAincreases expression 17522070
D005996 Nitroglycerin Nitroglycerin results in increased expression of APEX1 mRNAincreases expression 12102619
D010126 Ozone [Ozone co-treated with Chlorine] results in decreased expression of APEX1 mRNAaffects cotreatment|decreases expression 18636392
D010126 Ozone Ozone results in increased expression of APEX1 mRNAincreases expression 16330353
D010269 Paraquat APEX1 gene mutant form results in increased susceptibility to Paraquatincreases response to substance 11454706
D010882 Piperonyl Butoxide Piperonyl Butoxide results in increased expression of APEX1 mRNAincreases expression 15890375
C006253 pirinixic acid pirinixic acid results in increased expression of APEX1 mRNAincreases expression 18301758
C006253 pirinixic acid pirinixic acid results in increased expression of APEX1 mRNAincreases expression 15890375
20127075
D011160 Porfiromycin APEX1 protein results in increased reduction of and results in increased susceptibility to Porfiromycinincreases reduction|increases response to substance 10190555
C035988 procymidone procymidone results in increased expression of APEX1 mRNAincreases expression 15686871
D011374 Progesterone Progesterone results in decreased expression of APEX1 mRNAdecreases expression 18037150
C031280 pyrazole pyrazole results in increased expression of APEX1 mRNAincreases expression 17945193
D020849 Raloxifene [Raloxifene co-treated with Kainic Acid] results in increased expression of APEX1 mRNAaffects cotreatment|increases expression 16120186
D020849 Raloxifene Raloxifene results in increased expression of APEX1 mRNAincreases expression 16120186
C059514 resveratrol resveratrol results in decreased activity of APEX1 proteindecreases activity 16373707
C009277 sodium arsenate sodium arsenate results in increased expression of APEX1 mRNAincreases expression 16882884
C017947 sodium arsenite sodium arsenite results in decreased expression of APEX1 mRNAdecreases expression 12760830
12377979
C017947 sodium arsenite sodium arsenite results in increased expression of APEX1 mRNAincreases expression 17451858
D018038 Sodium Selenite Sodium Selenite results in increased expression of APEX1 mRNAincreases expression 18175754
D013629 Tamoxifen Tamoxifen affects the expression of APEX1 mRNAaffects expression 17555576
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of APEX1 mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of APEX1 mRNAincreases expression 17942748
D013752 Tetracycline Tetracycline results in increased expression of APEX1 mRNAincreases expression 17522070
D013806 Theophylline Theophylline results in decreased expression of APEX1 mRNAdecreases expression 17522070
D014028 Tobacco Smoke Pollution Tobacco Smoke Pollution results in increased expression of APEX1 mRNAincreases expression 15289447
D014303 Trinitrotoluene Trinitrotoluene affects the expression of APEX1 mRNAaffects expression 21346803
D014810 Vitamin E Vitamin E results in increased expression of APEX1 mRNAincreases expression 19244175
D024483 Vitamin K 3 APEX1 gene mutant form results in increased susceptibility to Vitamin K 3increases response to substance 11454706
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 3.8714745880
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 6.3915322242 14514962 11752688
MESH:D000014 Abnormalities, Drug-Induced Trinitrotoluene 6.397525203
MESH:D000138 Acidosis Ammonium Chloride 2.9018287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.2717505938
MESH:D058186 Acute Kidney Injury Cisplatin 6.9117670903 15814532 12690470
MESH:D058186 Acute Kidney Injury resveratrol 6.9116538975
MESH:D055371 Acute Lung Injury Chlorine 7.1220601635
MESH:D055371 Acute Lung Injury pirinixic acid 7.1218653653
MESH:D000230 Adenocarcinoma Cisplatin 8.3417638652 11798837
MESH:D000230 Adenocarcinoma Dimethylnitrosamine 8.3416033868
MESH:D000230 Adenocarcinoma Estradiol 8.3411473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 8.3414692618
MESH:D002282 Adenocarcinoma, Bronchiolo-Alveolar Tobacco Smoke Pollution 4.8515814487
MESH:D000236 Adenoma 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 12.5916176798
MESH:D000236 Adenoma Diethylnitrosamine 12.596695378 10737359
MESH:D000236 Adenoma Dimethylnitrosamine 12.5919555203
MESH:D000236 Adenoma resveratrol 12.5915688382
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 13.4517620307 19052882 19061943 16434500 18056438 17162532
MESH:D018248 Adenoma, Liver Cell pirinixic acid 13.4516434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 13.4516835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.0215276417
MESH:D018246 Adrenocortical Adenoma Arsenic 11.5417306315
MESH:D018246 Adrenocortical Adenoma sodium arsenite 11.5417306315 16712894
MESH:D000382 Agricultural Workers' Diseases Paraquat 3.1211874814
MESH:D000419 Albuminuria Raloxifene 3.9617451421 17308373
MESH:D000544 Alzheimer Disease Ozone 5.5015513908
MESH:D000544 Alzheimer Disease Raloxifene 5.5015800139
MESH:D000544 Alzheimer Disease resveratrol 5.5016162502 16183991
MESH:D000686 Amyloidosis Diethylstilbestrol 3.8515469931
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.3711748828
MESH:D000799 Angioedema Acetaminophen 3.1710982225
MESH:D001005 Anus Neoplasms Dacarbazine 5.6112170190
MESH:D020261 Arsenic Poisoning Arsenic 2.6416251483 18414634 12569548 16835338
MESH:D001161 Arteriosclerosis Cyclophosphamide 8.0215014928
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 8.0211256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 5.8815885639
MESH:D001169 Arthritis, Experimental resveratrol 5.8817115116
MESH:D001172 Arthritis, Rheumatoid Ozone 4.3015570426
MESH:D001172 Arthritis, Rheumatoid Tobacco Smoke Pollution 4.3019898480
MESH:D001249 Asthma Ozone 4.6516373670 17854713
MESH:D001249 Asthma Theophylline 4.659701106 12113382
MESH:D050197 Atherosclerosis Arsenic 8.6419371607 12928151
MESH:D050197 Atherosclerosis Cadmium 8.6415687053
MESH:D050197 Atherosclerosis resveratrol 8.6417967414 16873680
MESH:D001321 Autistic Disorder Acetaminophen 1.5218445737
MESH:D001778 Blood Coagulation Disorders Clofibrate 11.9019483382
MESH:D001778 Blood Coagulation Disorders pirinixic acid 11.9019483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 11.9012125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.1115340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.3115746008
MESH:D019046 Bone Marrow Neoplasms Cisplatin 4.2114601052
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 4.6617868700
MESH:D001930 Brain Injuries Progesterone 8.8115665606 15380490 15845082
MESH:D001930 Brain Injuries Raloxifene 8.8116580743
MESH:D002545 Brain Ischemia resveratrol 3.6217600658
MESH:D001932 Brain Neoplasms Carmustine 7.8416187019
MESH:D001932 Brain Neoplasms Ethylene Oxide 7.8412562636
MESH:D001943 Breast Neoplasms 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 9.5820146248
MESH:D001943 Breast Neoplasms Cisplatin 9.5819526202 18382427
MESH:D001943 Breast Neoplasms Cyclophosphamide 9.5817020986 18234424 12006526 11325840 15136595 17388661 16978400 18323546 15093573
MESH:D001943 Breast Neoplasms Dacarbazine 9.5817983394
MESH:D001943 Breast Neoplasms Diethylnitrosamine 9.5817474063
MESH:D001943 Breast Neoplasms Diethylstilbestrol 9.5815324884 17129689
MESH:D001943 Breast Neoplasms Estradiol 9.5817289903 12948864 19861407 16675129 17018787 14630087 17261762 18497071
MESH:D001943 Breast Neoplasms Ethylene Oxide 9.5817162533 11921183
MESH:D001943 Breast Neoplasms Progesterone 9.5817614352 15562024 16175315
MESH:D001943 Breast Neoplasms Raloxifene 9.5817440819 15572757 17049068 15758505 17893378 17952589 15775269 17242785 16912660 17261762 16837676 17595753
MESH:D001943 Breast Neoplasms resveratrol 9.5816393696 17534123 17651959
MESH:D001943 Breast Neoplasms Tamoxifen 9.5819155303 19289846 16273361 19200415 18351453 19103187 18821012 18984771 18629630 20005174 11161223 20390343 19244106 20065188 18997820 20859285 19059307 16873071 19189210 18425577 17242785 17440819 19189212 17261762 16818667 21152245 18855134 15565566 19084267 17049068 19142967 19410462 16202921 19011961 20135344 18815881 19066611 19487384 19288272 21138602 19115204 15668708 19221464 20544844 17893378
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 9.5820435547
MESH:D016535 Bronchial Hyperreactivity Ozone 3.1415516495 19059883 18417511 18315731 17626835 16777450 14754758
MESH:D002100 Cachexia Ozone 4.0816183385
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 3.8016111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 7.793786805 18705752 16192424 15700767 16124888 15721981 16097048 16227642 16050911 15673190 16011737 10355542
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 7.7916050911
MESH:D002276 Carcinoid Tumor Dacarbazine 5.4716051944
MESH:D002277 Carcinoma Dimethylnitrosamine 6.5719555203
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 6.5716835633
MESH:D002280 Carcinoma, Basal Cell Arsenic 3.1817687452 15504454
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 3.8619066611
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 28.2816705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 28.283084413
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 28.2821507988 12619106 12907637
MESH:D006528 Carcinoma, Hepatocellular Arsenic 28.2816507464 17306315
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 28.2818788625
MESH:D006528 Carcinoma, Hepatocellular Cisplatin 28.2817982673
MESH:D006528 Carcinoma, Hepatocellular Cyclophosphamide 28.2819701751
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 28.2816328049 18506893 18210153 3581430 18393292 17138121 17761372 20084675 17055752 19701751 10672840 11831363 20214788 19171122 17978847 20524982 16935385 19519916 19208518 17428255 16569478 19394651 3084413 19539802 19919837 18785209 19052882 18978308 16502159 16779866 20514400 16288022 17162532 17173139 18971187 21159647 19418558 16807293 16540662 20935162 20512989 19335982 18665156 19822196 10737359 20007298 19107877 20101231 16830150 16878318 18494052 20727157 16698587 18788625 20432363 16681979 19383236 18056438 18691550
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 28.2816924424 15948411
MESH:D006528 Carcinoma, Hepatocellular Estradiol 28.2816924424
MESH:D006528 Carcinoma, Hepatocellular resveratrol 28.2816227395 19321006
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 28.2817306315 15276417 16507464
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 28.2816924424
MESH:D018827 Carcinoma, Lewis Lung Cyclophosphamide 9.2816152834
MESH:D018827 Carcinoma, Lewis Lung resveratrol 9.2816675471
MESH:D002289 Carcinoma, Non-Small-Cell Lung Cisplatin 4.9912023789 16685392
MESH:D002289 Carcinoma, Non-Small-Cell Lung Tobacco Smoke Pollution 4.9911212258
MESH:D002292 Carcinoma, Renal Cell Cyclophosphamide 6.1616201981
MESH:D002292 Carcinoma, Renal Cell Dacarbazine 6.1616201981
MESH:D002294 Carcinoma, Squamous Cell Arsenic 14.8118922899 15504454 17687452
MESH:D002294 Carcinoma, Squamous Cell Cisplatin 14.8117066447 6189445 18337622
MESH:D002294 Carcinoma, Squamous Cell Dimethylnitrosamine 14.8116033868
MESH:D002294 Carcinoma, Squamous Cell resveratrol 14.8116227395
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 14.8118572023
MESH:D002294 Carcinoma, Squamous Cell Tobacco Smoke Pollution 14.8111212258
MESH:D002295 Carcinoma, Transitional Cell Arsenic 12.5518640142
MESH:D002295 Carcinoma, Transitional Cell Raloxifene 12.5517572228
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 12.5517572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 1.9718670907 16120746 18850075
MESH:D009202 Cardiomyopathies Zalcitabine 4.2510591146
MESH:D002318 Cardiovascular Diseases Arsenic 13.4017938729 15738583 19152805
MESH:D002318 Cardiovascular Diseases Hydrogen Peroxide 13.4016936243
MESH:D002318 Cardiovascular Diseases Raloxifene 13.4015775269
MESH:D002318 Cardiovascular Diseases resveratrol 13.4015458977
MESH:D002340 Carotid Artery Diseases Arsenic 3.7418022660 16973168
MESH:D002386 Cataract Acetaminophen 6.0810977129
MESH:D002386 Cataract Trinitrotoluene 6.0814694615 15817613
MESH:D002471 Cell Transformation, Neoplastic Cadmium 16.0217332340
MESH:D002471 Cell Transformation, Neoplastic Clofibrate 16.021399818
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 16.022727394 21159647 7505956 17174075
MESH:D002471 Cell Transformation, Neoplastic Estradiol 16.0218566989
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 16.0220056578 19524636
MESH:D002637 Chest Pain Theophylline 5.2015238202
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 7.4419052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 7.4416835633
MESH:D002761 Cholangitis 1-Naphthylisothiocyanate 5.5212912871
MESH:D002779 Cholestasis 1-Naphthylisothiocyanate 10.5818590720 12927374 16629650 15500046 18164287 15913567 7624871 19486331
MESH:D002779 Cholestasis Ethinyl Estradiol 10.5816919318 16105132 15861022 17681005 17110522 11677210 17333356
MESH:D002779 Cholestasis pirinixic acid 10.5819176532
MESH:D002780 Cholestasis, Intrahepatic 1-Naphthylisothiocyanate 5.1810220858 19407337
MESH:D019457 Chromosome Breakage Sodium Selenite 4.1015894690
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 1.7916354765 15668235 12621046 8697196 15340226
MESH:D003072 Cognition Disorders Raloxifene 3.9715800139
MESH:D003092 Colitis resveratrol 3.4916474422
MESH:D003110 Colonic Neoplasms arsenite 5.0315037631
MESH:D003110 Colonic Neoplasms Butyrates 5.0315936596
MESH:D003110 Colonic Neoplasms resveratrol 5.0316338953
MESH:D015179 Colorectal Neoplasms Cisplatin 3.2715273666
MESH:D015179 Colorectal Neoplasms Dacarbazine 3.2715273666
MESH:D015179 Colorectal Neoplasms resveratrol 3.2716550006
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 7.3917141729 14669216
MESH:D000013 Congenital Abnormalities Trinitrotoluene 7.3915095906
MESH:D003327 Coronary Disease resveratrol 3.2916507316
MESH:D019465 Craniofacial Abnormalities Lead 4.6319769572
MESH:D019465 Craniofacial Abnormalities sodium arsenate 4.6310525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 4.6310048152 20055451 15322242
MESH:D019465 Craniofacial Abnormalities Vitamin E 4.6319769572
MESH:D003456 Cryptorchidism Diethylstilbestrol 3.9216002989 12952375
MESH:D003490 Cyanosis 2,4-dinitrotoluene 9.0718551238
MESH:D003490 Cyanosis Trinitrotoluene 9.0718551238
MESH:D003556 Cystitis Cyclophosphamide 4.3118372110 18295254 16614059 10700343 16413132 17979934 18093676 18483878 10498854 15643279 16989017 12913760 11948286 18710439 12388444 16651033 17010015 15276878 18433785 12161096
MESH:D003704 Dementia Lead 4.6516140633
MESH:D003711 Demyelinating Diseases Tamoxifen 3.7119031437
MESH:D003865 Depressive Disorder, Major Raloxifene 3.5917474826
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.0818249437
MESH:D003920 Diabetes Mellitus Sodium Selenite 3.2116285004
MESH:D003921 Diabetes Mellitus, Experimental Cyclophosphamide 6.8515331540 10990075 11751995
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 6.8516873680
MESH:D003922 Diabetes Mellitus, Type 1 Cyclophosphamide 2.9718772604
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 3.5020387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 3.5017107852
MESH:D003928 Diabetic Nephropathies Estradiol 16.8019279558
MESH:D003928 Diabetic Nephropathies Raloxifene 16.8017308373 17451421 15920148
MESH:D003928 Diabetic Nephropathies resveratrol 16.8016286809
MESH:D003928 Diabetic Nephropathies Tamoxifen 16.8019279558
MESH:D003929 Diabetic Neuropathies Progesterone 3.8417187935
MESH:D004342 Drug Hypersensitivity Dacarbazine 4.5216508601
MESH:D056486 Drug-Induced Liver Injury 1-Naphthylisothiocyanate 45.4218289764 17522070 7624871 20133375
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 45.4218551238 21346803
MESH:D056486 Drug-Induced Liver Injury 2-nitropropane 45.4215804453 20517888 16445897
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 45.4211461765 10774834 14550746 19370779 17906064 17562736 11743745 16485898 18071297 18713872 12540782 12392966 19416960 16393943 14725611 11529661 16781746 12153990 11739529 10663392 12705907 16227642 11287661 19164858 19085960 16081117 10915739 11421492 17522070 19739265 2444490 12594235 14986274 19923254 16109766 15968718 16177239 12958197 15619225 19420014 11834606
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 45.4216177239 6884620 3786805 16227642 7440962 21278145 15968718 7179309 4309450 17522070 19085960 10092053 7120509 9327722 19336974 10915739 3732212 15027814 11566570 2869522 15998439 6623471
MESH:D056486 Drug-Induced Liver Injury Chloroform 45.423104120 17522070 6884620 6623471 3732212 2862719 7440962 7120509
MESH:D056486 Drug-Induced Liver Injury cyanoginosin LR 45.4217654400
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 45.4219107877
MESH:D056486 Drug-Induced Liver Injury Dimethylnitrosamine 45.428172417
MESH:D056486 Drug-Induced Liver Injury Erythromycin Estolate 45.4214998559 17522070
MESH:D056486 Drug-Induced Liver Injury pyrazole 45.4212499123
MESH:D056486 Drug-Induced Liver Injury sodium arsenate 45.4218186108
MESH:D056486 Drug-Induced Liver Injury Sodium Selenite 45.4215131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 45.4220420201
MESH:D056486 Drug-Induced Liver Injury Tetracycline 45.4217522070
MESH:D056486 Drug-Induced Liver Injury Trinitrotoluene 45.4221346803 18551238
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.4219426721
MESH:D004362 Drug Toxicity Cisplatin 10.9812649298 19839026 12231392 15033597
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 10.9811462148
MESH:D004362 Drug Toxicity Zalcitabine 10.987515130
MESH:D050171 Dyslipidemias Clofibrate 7.5116707586
MESH:D050171 Dyslipidemias Fenofibrate 7.5116707586
MESH:D004417 Dyspnea Chlorine 3.9520016425
MESH:C538011 Eales disease Vitamin E 4.039068938
MESH:D004487 Edema pirinixic acid 11.6212083418
MESH:D004487 Edema Raloxifene 11.6215860553
MESH:D004487 Edema resveratrol 11.628985016
MESH:D004487 Edema Tetrachlorodibenzodioxin 11.6212711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.2315322242 18230668 16714409
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 22.0812538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 22.0817692515
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Raloxifene 22.0815845917
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 22.0817872969
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 22.0819031437
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 4.0316402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 14.0216804899 15700306
MESH:D016889 Endometrial Neoplasms Estradiol 14.0211473722 18566989 19148513
MESH:D016889 Endometrial Neoplasms Fenofibrate 14.0216569247
MESH:D016889 Endometrial Neoplasms Tamoxifen 14.0217893378 20544844 16202921 19155303
MESH:D004715 Endometriosis Progesterone 7.0016134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 7.0010568697 9294722
MESH:D020345 Enterocolitis, Necrotizing resveratrol 4.2017923197
MESH:D004802 Eosinophilia Cyclophosphamide 3.5811006010
MESH:D004832 Epilepsy, Absence Naloxone 4.686254150
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.4416302075
MESH:D004938 Esophageal Neoplasms Cisplatin 4.2016785472 16481741 15464296 15173087 17638652
MESH:D004938 Esophageal Neoplasms Dimethylnitrosamine 4.2017016578
MESH:D020329 Essential Tremor Lead 5.2614594619 18007985
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.5011564622
MESH:D005234 Fatty Liver arsenite 43.4218296743
MESH:D005234 Fatty Liver Carbon Tetrachloride 43.4212631006 16045604 12795759 15959796 19224547 17595544 61145 16239168
MESH:D005234 Fatty Liver Clofibrate 43.4219224547
MESH:D005234 Fatty Liver Diethylnitrosamine 43.4221071580 20387270
MESH:D005234 Fatty Liver Ethinyl Estradiol 43.4215345470
MESH:D005234 Fatty Liver pirinixic acid 43.4220131406 19236843
MESH:D005234 Fatty Liver Raloxifene 43.4217473493
MESH:D005234 Fatty Liver Tamoxifen 43.4219224547 14986274
MESH:D005234 Fatty Liver Tetracycline 43.4219224547 16917069
MESH:D005234 Fatty Liver Zalcitabine 43.4218299183
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 6.7416611131 16534752 16002989 15751030 16513791
MESH:D052776 Female Urogenital Diseases Tamoxifen 6.7416709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 2.8111858732
MESH:D005317 Fetal Growth Retardation Lead 4.9119769572
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 3.8614745880
MESH:D018222 Fibromatosis, Aggressive Dacarbazine 9.7319069698
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 9.7319069698
MESH:D005355 Fibrosis arsenite 11.1118296743
MESH:D005355 Fibrosis Carbon Tetrachloride 11.1118705752
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 11.1120067830
MESH:D005534 Foot Diseases Arsenic 4.886392382
MESH:D005739 Gas Poisoning Chlorine 4.3320016425
MESH:D005756 Gastritis Acetaminophen 3.0016983495
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 10.6116452187
MESH:D005833 Genital Neoplasms, Female sodium arsenite 10.6116452187
MESH:D005909 Glioblastoma Carmustine 6.5416187019
MESH:D005909 Glioblastoma Dacarbazine 6.5412592361 12853885
MESH:D018316 Gliosarcoma Cyclophosphamide 4.8511389073
MESH:D005911 Gliosis Paraquat 4.4911124998
MESH:D018149 Glucose Intolerance sodium arsenate 4.4619446573
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 3.9210696789
MESH:D006086 Graft vs Host Disease Cyclophosphamide 4.3916376943 11014644 15172196
MESH:D006261 Headache Nitroglycerin 4.5211284996 11554966
MESH:D006258 Head and Neck Neoplasms Cisplatin 3.2415464296 15102660
MESH:D034381 Hearing Loss Cisplatin 3.7319898482
MESH:D006319 Hearing Loss, Sensorineural Cisplatin 3.8615464296
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 5.2610048152 11294989
MESH:D006330 Heart Defects, Congenital Vitamin E 5.2616080930
MESH:D006331 Heart Diseases Raloxifene 3.0611110106
MESH:D006333 Heart Failure pirinixic acid 2.1020558911
MESH:D006467 Hemophilia A Cyclophosphamide 4.6411918545
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.7411000095
MESH:D006504 Hepatic Veno-Occlusive Disease Cyclophosphamide 4.8614986274
MESH:D006505 Hepatitis 1-Naphthylisothiocyanate 7.5718590720
MESH:D006505 Hepatitis Carbon Tetrachloride 7.5719900420 19110552
MESH:D006529 Hepatomegaly pirinixic acid 10.7616221962 18467677 19176532 19772884
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 10.7615340226 12621046 16120746
MESH:D006529 Hepatomegaly Trinitrotoluene 10.7615817613
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.4316490937 16863852
MESH:D006558 Herpes Genitalis Estradiol 4.3515709030
MESH:D006561 Herpes Simplex resveratrol 3.5216876885
MESH:D015658 HIV Infections Zalcitabine 3.9617457083
MESH:D006689 Hodgkin Disease Cisplatin 12.9916170182 16200630
MESH:D006689 Hodgkin Disease Cyclophosphamide 12.9917606976 16135485
MESH:D006689 Hodgkin Disease Dacarbazine 12.9918501091 16170182
MESH:D006689 Hodgkin Disease sodium arsenite 12.9912676792
MESH:D019584 Hot Flashes Estradiol 7.8117088409
MESH:D019584 Hot Flashes Vitamin E 7.8114716179
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.3716959395 15340226 18606429 8697196 16354765
MESH:D006930 Hyperalgesia Acetaminophen 2.1716870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 3.8716899240
MESH:D006937 Hypercholesterolemia resveratrol 3.4117188708
MESH:D006943 Hyperglycemia pirinixic acid 2.6020558911
MESH:D017488 Hyperkeratosis, Epidermolytic Arsenic 3.8717050553
MESH:D006949 Hyperlipidemias resveratrol 3.4216873680
MESH:D006965 Hyperplasia Diethylstilbestrol 3.7914722030 12960047
MESH:D006973 Hypertension Arsenic 6.909931084 11953799 16076760
MESH:D006973 Hypertension Raloxifene 6.9015787275 17577099
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 6.9018670907 18850075
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.4415338365
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 3.7217488730
MESH:D006987 Hypesthesia Arsenic 4.8816093927
MESH:D007021 Hypospadias Diethylstilbestrol 9.0916002989
MESH:D007021 Hypospadias Ethinyl Estradiol 9.0916569931 16945680
MESH:D007154 Immune System Diseases Cyclophosphamide 4.6516076520
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 9.3315869954
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 9.3317600658
MESH:D007246 Infertility Diethylstilbestrol 3.7215036965
MESH:D007247 Infertility, Female Ethinyl Estradiol 2.8512013081
MESH:D007248 Infertility, Male Cyclophosphamide 24.6216517039 7193160
MESH:D007248 Infertility, Male Ethinyl Estradiol 24.6217937319
MESH:D007248 Infertility, Male Lead 24.6216780224
MESH:D007248 Infertility, Male Paraquat 24.624850670
MESH:D007248 Infertility, Male sodium arsenite 24.6212646999 15346721
MESH:D007248 Infertility, Male Theophylline 24.6216988215
MESH:D007248 Infertility, Male Trinitrotoluene 24.6212150543
MESH:D007249 Inflammation Diethylnitrosamine 14.9118785209
MESH:D007249 Inflammation Progesterone 14.9115869954
MESH:D007249 Inflammation resveratrol 14.9116366677
MESH:D007249 Inflammation Tamoxifen 14.9119457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 14.9112200463 12878042
MESH:D007249 Inflammation Tobacco Smoke Pollution 14.9118590791
MESH:D007251 Influenza, Human resveratrol 8.8416624496
MESH:D007251 Influenza, Human Vitamin E 8.8416624496
MESH:D007333 Insulin Resistance Estradiol 9.6216627594 16393666
MESH:D007333 Insulin Resistance pirinixic acid 9.6216306350
MESH:D007333 Insulin Resistance Sodium Selenite 9.6214714311
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 2.7416580747
MESH:D007642 Keratosis Arsenic 4.3316930632 12749816
MESH:D007673 Kidney Cortex Necrosis Cisplatin 4.4615464296
MESH:D007674 Kidney Diseases Acetaminophen 18.4115629191 12587719
MESH:D007674 Kidney Diseases Cadmium 18.4116962696 16322080 16226777
MESH:D007674 Kidney Diseases Cisplatin 18.4112231392 18289764 12649298 15190930 19839026
MESH:D007674 Kidney Diseases Estradiol 18.4115618244
MESH:D007674 Kidney Diseases sodium arsenite 18.4120008137
MESH:D007674 Kidney Diseases Vitamin E 18.4112488133
MESH:D007676 Kidney Failure, Chronic Hydrogen Peroxide 3.6816518626
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 13.2916705839
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 13.2915003126 14681315 16762066
MESH:D007680 Kidney Neoplasms Estradiol 13.2915610895
MESH:D007680 Kidney Neoplasms Tamoxifen 13.2918625569
MESH:D007683 Kidney Tubular Necrosis, Acute Cisplatin 4.1211231351
MESH:D007855 Lead Poisoning Lead 5.2616700817
MESH:D007859 Learning Disorders Diethylstilbestrol 8.0017184923
MESH:D007859 Learning Disorders Lead 8.0016384672
MESH:D007889 Leiomyoma Raloxifene 3.8816973256
MESH:D007938 Leukemia Cyclophosphamide 3.1310602166
MESH:D015451 Leukemia, Lymphocytic, Chronic, B-Cell Cyclophosphamide 3.1717296974 17802794 18587576 17658394 17008537 18172266
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Cyclophosphamide 3.5810373061
MESH:D015473 Leukemia, Promyelocytic, Acute Arsenic 6.3717339181
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 6.3716087638
MESH:D007970 Leukopenia Cyclophosphamide 4.3010052129 11830472
MESH:D008064 Lipidoses Tamoxifen 2.6617567588 15342952
MESH:D008103 Liver Cirrhosis arsenite 8.7218296743
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 8.7217157831 16943688 16239168 11408273 21278145 11903743 17334410 16221502 17174718
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 8.7219638242 20032147 18407596 18665156 18522880
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 11.0515925388 17869086 18006644 18705752 14620537 18472332 15338365 16116963 17761835 18420326 12389079 18481824 17698563 16011737 15818738 16192424 17805973 16033810 15730626 18317297 12666154 15362042 17823541 11481614 14512876 17900296 15370692 18395095 14716496 16097048 17708605 16136751 12632514 18472094 18210741 18263696 16015684 17976157 12445418 18339082 16248980 18166357 18054572 16638106 15673190 12632512 18429990 18277467 17721639 17766677 12586293 14748882 18205269 17922224 18279442 17944888 12667390 15931870 15876570 12609069 15996030 15959796 18376398 15052691 17525996 15123356 10355542 17565644 17714472 12649538 18395914 20821823 12741479 15893842 18412020 14716833 18251166 17631135 17640975 18187930 12445421 15057751 12898905 14724832 12546737 17481882 13678700 15650968 18156304 18418968 12958196 17557913 16027843
MESH:D008106 Liver Cirrhosis, Experimental Dimethylnitrosamine 11.0515842777 16169303 15366600 18239293 16570917 16627068 16603200 16009107 18637143 14568256 17201889 17724770 15504291 17198567 15086199 17465448 18629640 17719030 16270385 15099470 18237412 15479170 15383259 15571005 18371158 15577212 14643895 15763062 15723089 17881167 15798949 15864749 12918455 12925901 15161499 17036385 15733078 15492853 15744066 17666798 15369754 14709902 17203207 14659978 17640959 17348192 18567088 18672772 17534399 18210741 15793283 15067225 14726149 17196135 15339415 16544323 15591649 16042886 15298665 15942678 18364076 15138612 18095165 17432682 15081153
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 11.0514659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental Fenofibrate 11.0515474484
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 11.0515474484
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 11.0518564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 11.0512878042
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 11.0516169303
MESH:D008107 Liver Diseases 1-Naphthylisothiocyanate 10.0817184895
MESH:D008107 Liver Diseases Acetaminophen 10.0812969438 19460945 16611625 19784758 11587558 19014921 16610002 12587719
MESH:D008107 Liver Diseases Arsenic 10.0811134558
MESH:D008107 Liver Diseases Carbon Tetrachloride 10.0815830285 16964402 16246199 17285989 15720792
MESH:D008107 Liver Diseases Diethylnitrosamine 10.0817034775
MESH:D017093 Liver Failure Carbon Tetrachloride 3.5215123358
MESH:D017114 Liver Failure, Acute Acetaminophen 12.9016871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 12.9014706259 16899240
MESH:D017114 Liver Failure, Acute Dimethylnitrosamine 12.9017457977
MESH:D008113 Liver Neoplasms 2-nitrofluorene 60.0615890375
MESH:D008113 Liver Neoplasms 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 60.0615890375
MESH:D008113 Liver Neoplasms Aflatoxin B1 60.0615890375 9163691 18177683 2125692
MESH:D008113 Liver Neoplasms Arsenic 60.0616368122
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 60.0619294768
MESH:D008113 Liver Neoplasms Clofibric Acid 60.0617602206
MESH:D008113 Liver Neoplasms Diethylnitrosamine 60.0620101389 19426721 18648771 21071580 20452335 12771043 19812893 19427195 15175105 20492335 19254457 21047994 18644402 19642983 18977376 19833225 18754104 16942905 15885732 20137499 19850985 19073162 19255062 2862719 19090486 10737359 19294768 19499222 20434301 21167192 19551842 21278145 19996281 19256749 2422723 19638242 20583210 12112319 20118626 20405173 20501860 9163691 18978307 19690152
MESH:D008113 Liver Neoplasms Diethylstilbestrol 60.0615890375 16712894
MESH:D008113 Liver Neoplasms Dimethylnitrosamine 60.0615890375 3113478
MESH:D008113 Liver Neoplasms Fenofibrate 60.0618978307
MESH:D008113 Liver Neoplasms Methapyrilene 60.0615890375
MESH:D008113 Liver Neoplasms Mitomycin 60.0615113037
MESH:D008113 Liver Neoplasms Piperonyl Butoxide 60.0620101389 15890375 18648771 19690152
MESH:D008113 Liver Neoplasms pirinixic acid 60.0620007298 16377806 15890375
MESH:D008113 Liver Neoplasms resveratrol 60.0619321006 19073162 19812893 20405173
MESH:D008113 Liver Neoplasms sodium arsenite 60.0615276417 16712894
MESH:D008113 Liver Neoplasms Tamoxifen 60.0616684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 60.0616984957
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 17.598603461
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 17.5915583823 12014681
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 17.5918079962 18308698 18544905 18253720 18775883 17942915 2563599 18093689 19539802 18164116 17854601 19126423 19519916 16842330 21159647 3124819 19004024 9362446 18282651 17174075 16267830 19009564
MESH:D008114 Liver Neoplasms, Experimental Dimethylnitrosamine 17.5915603536 1848544 6150874
MESH:D008114 Liver Neoplasms, Experimental Fenofibrate 17.5918253720 18775883
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 17.5912151625
MESH:D008171 Lung Diseases Ozone 9.6219066396 8266340
MESH:D008171 Lung Diseases sodium arsenite 9.6219095001
MESH:D008171 Lung Diseases Vitamin E 9.6216863852
MESH:D055370 Lung Injury Ozone 3.2120417186
MESH:D008175 Lung Neoplasms 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 25.119255578 18508827 18813816 12438228 16401635 15172992 17139156 19931552 16061637 14755239 15893417
MESH:D008175 Lung Neoplasms Aflatoxin B1 25.1114755239
MESH:D008175 Lung Neoplasms Arsenic 25.1117976673 19168569 17306315
MESH:D008175 Lung Neoplasms arsenite 25.1116809336
MESH:D008175 Lung Neoplasms Cisplatin 25.1117225452 11798837 6189445
MESH:D008175 Lung Neoplasms Diethylnitrosamine 25.1120970405 21163286 20512841 6695378
MESH:D008175 Lung Neoplasms Dimethylnitrosamine 25.1116061637 11884234 19555203
MESH:D008175 Lung Neoplasms Ethylene Oxide 25.1117325976 12562636
MESH:D008175 Lung Neoplasms Ozone 25.117614698 8597069
MESH:D008175 Lung Neoplasms sodium arsenite 25.1115276417 16712894 19931552 17077188 17306315
MESH:D008175 Lung Neoplasms Tamoxifen 25.1118625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 25.1111884234 19555203
MESH:D008175 Lung Neoplasms Tobacco Smoke Pollution 25.113440675 11091918 16288123 12111688
MESH:D008175 Lung Neoplasms Vitamin E 25.1111062179
MESH:D008181 Lupus Nephritis Diethylstilbestrol 4.4815166399
MESH:D008223 Lymphoma Cyclophosphamide 9.9812854902
MESH:D008223 Lymphoma Diethylstilbestrol 9.9815700306
MESH:D008223 Lymphoma Zalcitabine 9.9811980663 18798262 9205081 9488045 17941976 8764131 8840982
MESH:D016393 Lymphoma, B-Cell Cyclophosphamide 13.6516675587
MESH:D016393 Lymphoma, B-Cell resveratrol 13.6517088997
MESH:D016393 Lymphoma, B-Cell Sodium Selenite 13.6514737004
MESH:D008228 Lymphoma, Non-Hodgkin Cyclophosphamide 7.1911911406
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 7.1914749477
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 4.8416002989
MESH:D015674 Mammary Neoplasms, Animal Ethylene Oxide 13.1912562636
MESH:D015674 Mammary Neoplasms, Animal resveratrol 13.1915688416
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 13.1919428831
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 14.0217203775 11807958 16891317 11408345
MESH:D008325 Mammary Neoplasms, Experimental Ethylene Oxide 14.0211921183
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 14.0217203775 11408345
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 14.028985016 11606380
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 14.0211731420 19196722 19196723 14580682 16827153
MESH:D020149 Manganese Poisoning Estradiol 10.4019453300
MESH:D020149 Manganese Poisoning Tamoxifen 10.4019453300
MESH:D008545 Melanoma marker/mechanism 16373707
MESH:D008545 Melanoma Carmustine 12.7912393984
MESH:D008545 Melanoma Cisplatin 12.7918505091 11135225 12374674 18176117 17023156 12883367 17761969 18332650 16809738 16432458 16248763 12393984 15577323
MESH:D008545 Melanoma Dacarbazine 12.7916248763 17623835 16939954 11746506 15577323 11712820 15917704 16273263 16809738 11254118 18089842 18332650 15522559 10623706 12556972 17562445 16098027 12417787 15176220 17239242 17334785 12202904 16034308 18445842 18176117 17761969 17973783 16760174 17119449 12535206 12439608 12883367 15020614 17023156 17576460 11135225 12025231 16225601 18505091 16966688 12393984 15577320 12640292 17709802 18281670 16508601 16928243 17508024
MESH:D008545 Melanoma resveratrol 12.7917992120
MESH:D008545 Melanoma sodium arsenite 12.7919082730 16487513
MESH:D008545 Melanoma Tamoxifen 12.7912393984 19393235
MESH:D008545 Melanoma Vitamin K 3 12.7919082730
MESH:D018328 Melanoma, Amelanotic Cisplatin 15.8515990972
MESH:D018328 Melanoma, Amelanotic Dacarbazine 15.8515990972
MESH:D018328 Melanoma, Amelanotic Tamoxifen 15.8515990972
MESH:D008546 Melanoma, Experimental Acetaminophen 8.6819513568
MESH:D008546 Melanoma, Experimental Cyclophosphamide 8.6816388313
MESH:D008569 Memory Disorders Lead 4.5416384672 17263510
MESH:D008654 Mesothelioma Cisplatin 2.9417638057
MESH:D008659 Metabolic Diseases resveratrol 3.7817112576
MESH:D008679 Metaplasia Ozone 4.4310496685
MESH:D008708 Methemoglobinemia Nitroglycerin 4.133537620
MESH:D020326 Migraine without Aura Nitroglycerin 4.4914659530
MESH:D018200 Mixed Tumor, Mullerian Raloxifene 4.8815863610
MESH:D009062 Mouth Neoplasms Tobacco Smoke Pollution 3.8315006635
MESH:D009101 Multiple Myeloma Raloxifene 5.9016497877
MESH:D009101 Multiple Myeloma resveratrol 5.9017164350 17049120 14749477 16490592 16267019 17935668
MESH:D009134 Muscular Atrophy, Spinal resveratrol 4.2117962980
MESH:D009135 Muscular Diseases Bezafibrate 8.5816239165
MESH:D009135 Muscular Diseases pirinixic acid 8.5816239165
MESH:D009139 Musculoskeletal Abnormalities sodium arsenate 4.2618186108
MESH:D009203 Myocardial Infarction Nitroglycerin 7.7014729435
MESH:D009203 Myocardial Infarction pirinixic acid 7.7019151258
MESH:D009203 Myocardial Infarction resveratrol 7.7017188708 16456233 16525036 17125593 17015251 16317513
MESH:D017202 Myocardial Ischemia Arsenic 12.1815371236
MESH:D017202 Myocardial Ischemia resveratrol 12.1817015251 17125593
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 12.1812213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 6.5116810080
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 6.5116411023
MESH:D009205 Myocarditis resveratrol 4.1017322642
MESH:D009232 Myxoma Raloxifene 4.8816343187
MESH:D009336 Necrosis 2,4-dinitrotoluene 14.1918551238
MESH:D009336 Necrosis 2-nitropropane 14.1912195237
MESH:D009336 Necrosis Trinitrotoluene 14.1918551238
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 4.673581430 9029167
MESH:D009362 Neoplasm Metastasis Tamoxifen 4.6719393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.2619410462
MESH:D009369 Neoplasms Cisplatin 11.7616773208
MESH:D009369 Neoplasms Cyclophosphamide 11.7618854779
MESH:D009369 Neoplasms Diethylstilbestrol 11.7615313581
MESH:D009369 Neoplasms pirinixic acid 11.7617405874
MESH:D009369 Neoplasms sodium arsenite 11.7611559025
MESH:D009374 Neoplasms, Experimental resveratrol 11.778985016
MESH:D009374 Neoplasms, Experimental sodium arsenite 11.7720056578
MESH:D009374 Neoplasms, Experimental Zalcitabine 11.779488045 9205081 8764131
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.3319200415 19196722 19189210
MESH:D009389 Neovascularization, Pathologic arsenite 7.9615738583
MESH:D009389 Neovascularization, Pathologic Estradiol 7.9617289903
MESH:D009395 Nephritis, Interstitial Cisplatin 8.6015464296
MESH:D009395 Nephritis, Interstitial Tetracycline 8.609884423
MESH:D009410 Nerve Degeneration Paraquat 3.1916893418
MESH:D009421 Nervous System Malformations Diethylstilbestrol 12.7411399458
MESH:D009421 Nervous System Malformations Estradiol 12.7416427766 11399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 12.7414600291
MESH:D009437 Neuralgia Zalcitabine 5.6517292584
MESH:D009436 Neural Tube Defects Arsenic 9.6316620997
MESH:D009436 Neural Tube Defects sodium arsenate 9.6311749123 10525206 19446573 18186108
MESH:D009436 Neural Tube Defects sodium arsenite 9.6312854658
MESH:D009447 Neuroblastoma Cisplatin 5.998761367
MESH:D009447 Neuroblastoma Cyclophosphamide 5.9916115947 15176712 8761367
MESH:D019636 Neurodegenerative Diseases Acetaminophen 10.8718514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 10.8720387270
MESH:D019636 Neurodegenerative Diseases resveratrol 10.8717652729
MESH:D017599 Neuroectodermal Tumors Cisplatin 9.328761367
MESH:D017599 Neuroectodermal Tumors Cyclophosphamide 9.328761367 12837982
MESH:D020078 Neurogenic Inflammation Arsenic 8.6617056641
MESH:D020078 Neurogenic Inflammation resveratrol 8.6617929310
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.4420387270
MESH:D009503 Neutropenia Cyclophosphamide 3.728291058
MESH:D052556 Niemann-Pick Disease, Type C Clofibrate 4.299802331
MESH:D009765 Obesity pirinixic acid 1.6220558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 7.2912819281 16049721
MESH:D009784 Occupational Diseases Trinitrotoluene 7.2912819281 17852074 14694615
MESH:D009845 Oligospermia Cyclophosphamide 4.0516517039
MESH:D010024 Osteoporosis Raloxifene 2.9615775268 17882678 19059307
MESH:D015663 Osteoporosis, Postmenopausal Raloxifene 8.1617893378 17823083 15758505 15579764
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 8.1617513867
MESH:D010051 Ovarian Neoplasms Arsenic 12.1417306315
MESH:D010051 Ovarian Neoplasms Cisplatin 12.1415464296 17225452 19769630 6897625
MESH:D010051 Ovarian Neoplasms Estradiol 12.1419401270
MESH:D010051 Ovarian Neoplasms Progesterone 12.1416525653 17393432
MESH:D010051 Ovarian Neoplasms sodium arsenite 12.1417306315 15276417
MESH:D010146 Pain Acetaminophen 5.0716870215
MESH:D010146 Pain Cyclophosphamide 5.0712161096 18093676
MESH:D010190 Pancreatic Neoplasms 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 16.6912384795
MESH:D010190 Pancreatic Neoplasms Cisplatin 16.6919003803
MESH:D010190 Pancreatic Neoplasms Cyclophosphamide 16.6911332152
MESH:D010190 Pancreatic Neoplasms Dacarbazine 16.6911583197
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 16.6916540662
MESH:D010190 Pancreatic Neoplasms Mitomycin 16.6915113037
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.0711578682
MESH:D010212 Papilloma Hydrogen Peroxide 3.4512065085
MESH:D010300 Parkinson Disease Paraquat 2.5312911755 11445065 11124998 15451049 15824117 16510128 11181820 16140633
MESH:D010302 Parkinson Disease, Secondary Paraquat 3.7816190885
MESH:D010382 Peliosis Hepatis 1-Naphthylisothiocyanate 11.5420133375
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 11.5412520081
MESH:D010391 Pemphigoid, Bullous Tetracycline 4.7611026799
MESH:D010523 Peripheral Nervous System Diseases Arsenic 13.1116093927
MESH:D010523 Peripheral Nervous System Diseases Cisplatin 13.1115464296
MESH:D010523 Peripheral Nervous System Diseases Zalcitabine 13.1118606552
MESH:D016491 Peripheral Vascular Diseases Arsenic 10.8816905509 15371236 6392382
MESH:D016491 Peripheral Vascular Diseases Cadmium 10.8815687053
MESH:D010538 Peritonitis Ozone 3.4916369182
MESH:D003557 Phyllodes Tumor Dacarbazine 5.8217983394
MESH:D010900 Pituitary Diseases Diethylstilbestrol 4.4914722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 4.0215687265 16977796
MESH:D010997 Pleural Neoplasms Cisplatin 4.6717638057
MESH:D011014 Pneumonia Ozone 8.8718007984 18929643 18381685
MESH:D011014 Pneumonia Paraquat 8.8712504350
MESH:D011115 Polyneuropathies Ethylene Oxide 5.518472653
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 2.9318163543
MESH:D011230 Precancerous Conditions Diethylnitrosamine 2.992563599
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Cyclophosphamide 6.8921297632
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Daunorubicin 6.8921297632
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 17.9217184923
MESH:D011297 Prenatal Exposure Delayed Effects Lead 17.9216384672
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 17.9216679765
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 17.9211399792 11118676 11222880 11896295
MESH:D017096 Prion Diseases Tetracycline 4.7510903871
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.2820887781
MESH:D011471 Prostatic Neoplasms marker/mechanism 16406883
MESH:D011471 Prostatic Neoplasms Arsenic 3.6816140617
MESH:D011471 Prostatic Neoplasms Cadmium 3.6817075824
MESH:D011471 Prostatic Neoplasms Cyclophosphamide 3.6817136230
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 3.6815846301 15046698 17136230
MESH:D011471 Prostatic Neoplasms Estradiol 3.6816740699
MESH:D011471 Prostatic Neoplasms Raloxifene 3.6815731164 16536755 16220300
MESH:D011471 Prostatic Neoplasms resveratrol 3.6817804756 17718901 17675339 15767336 17636462 16731767
MESH:D011471 Prostatic Neoplasms sodium arsenite 3.6816039940
MESH:D011471 Prostatic Neoplasms Sodium Selenite 3.6818760546
MESH:D011471 Prostatic Neoplasms Tamoxifen 3.6815067354
MESH:D011471 Prostatic Neoplasms Vitamin E 3.6815084515
MESH:D011507 Proteinuria Arsenic 3.4021343184
MESH:D011537 Pruritus Ethinyl Estradiol 7.8315861022 16919318
MESH:D011537 Pruritus Naloxone 7.8315861022
MESH:D029424 Pulmonary Disease, Chronic Obstructive Theophylline 4.6118983928
MESH:D011658 Pulmonary Fibrosis Cyclophosphamide 4.9716636934
MESH:D011658 Pulmonary Fibrosis Paraquat 4.9717997886 16324872
MESH:D011693 Purpura Raloxifene 4.8815770314
MESH:D051437 Renal Insufficiency Cisplatin 3.7615464296
MESH:D051436 Renal Insufficiency, Chronic resveratrol 4.9016325855
MESH:D015427 Reperfusion Injury pirinixic acid 5.3319058328
MESH:D015427 Reperfusion Injury resveratrol 5.3315827377 16314181 17058453 17520802 16317513
MESH:D012120 Respiration Disorders Chlorine 4.5418579056
MESH:D012128 Respiratory Distress Syndrome, Adult Paraquat 3.3011700416
MESH:D012135 Respiratory Sounds Paraquat 7.7911874814
MESH:D012135 Respiratory Sounds Tobacco Smoke Pollution 7.7918410779
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.2018990726
MESH:D012162 Retinal Degeneration Paraquat 3.3516458197
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.5818045962
MESH:D012509 Sarcoma Dacarbazine 4.7518313854 17898927
MESH:D012512 Sarcoma, Ewing's Cisplatin 3.8014601052
MESH:D012595 Scleroderma, Systemic Cyclophosphamide 4.2016636934
MESH:D012640 Seizures 2,4-dinitrotoluene 7.4118551238
MESH:D012640 Seizures Kainic Acid 7.4118657176 10686065 19186208 17827730 1641125 16336964 15686955 14637104 19414003
MESH:D012640 Seizures Trinitrotoluene 7.4118551238
MESH:D012871 Skin Diseases Arsenic 4.2919834688 17938729 6392382 17050553 16759981 15952646 16702368 17453740 18709164 17548696 16353154
MESH:D012871 Skin Diseases Vitamin E 4.2918709164
MESH:D012878 Skin Neoplasms Arsenic 17.7917029826 15504454 16251483 19538983 17050553 17976673
MESH:D012878 Skin Neoplasms Hydrogen Peroxide 17.7912065085
MESH:D012878 Skin Neoplasms resveratrol 17.7915837718 8985016
MESH:D012878 Skin Neoplasms sodium arsenite 17.7919524636 18572023
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 17.7916192470
MESH:D012878 Skin Neoplasms Tobacco Smoke Pollution 17.7918590791
MESH:D012893 Sleep Disorders Kainic Acid 5.0419414003
MESH:D055752 Small Cell Lung Carcinoma Cisplatin 4.6715464296
MESH:D013088 Spermatocele Diethylstilbestrol 16.2316709447 16002989
MESH:D013088 Spermatocele Ethinyl Estradiol 16.2316709447
MESH:D013088 Spermatocele Tamoxifen 16.2316709447
OMIM:102530 SPERMATOGENIC FAILURE 6 Cyclophosphamide 4.8516517039
MESH:D013119 Spinal Cord Injuries Progesterone 8.6715862959 16503802
MESH:D013119 Spinal Cord Injuries Tamoxifen 8.6719457130
MESH:D016135 Spinal Dysraphism sodium arsenite 3.2712854658
MESH:D013158 Splenic Diseases Dimethylnitrosamine 4.5912587719
MESH:D013163 Splenomegaly Trinitrotoluene 4.5515817613
MESH:D013274 Stomach Neoplasms Cisplatin 3.0218396642 15958060 17522103
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 3.0218456281
MESH:D013274 Stomach Neoplasms Dimethylnitrosamine 3.0216033868
MESH:D020521 Stroke Raloxifene 6.9216837676
MESH:D020521 Stroke Vitamin E 6.9216517955
OMIM:601367 STROKE, ISCHEMIC resveratrol 3.8916321402
MESH:D015173 Supratentorial Neoplasms Cyclophosphamide 4.3912837982
MESH:D024801 Tauopathies Daunorubicin 5.2016930453
MESH:D013733 Testicular Diseases pyrazole 4.166499806
MESH:D013736 Testicular Neoplasms Cisplatin 4.0115464296 17225452
MESH:D013921 Thrombocytopenia 1-Naphthylisothiocyanate 4.1720133375
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.0011994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.5915669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.2312697716
MESH:D013964 Thyroid Neoplasms Butyrates 9.3317967635
MESH:D013964 Thyroid Neoplasms Dacarbazine 9.3311815960 15634649
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 9.337505956
MESH:D013978 Tibial Fractures Estradiol 11.4619048282
MESH:D013978 Tibial Fractures Raloxifene 11.4619048282
MESH:D014062 Tongue Neoplasms resveratrol 3.6316227395
MESH:D014202 Tremor Lead 4.8221145352
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 26.7916049721
MESH:D001749 Urinary Bladder Neoplasms Arsenic 26.7915987713 17306315 18640142 19322015 19429237 11144890 17976673
MESH:D001749 Urinary Bladder Neoplasms Cisplatin 26.7917225452 12973940 15464296
MESH:D001749 Urinary Bladder Neoplasms Cyclophosphamide 26.7914692829
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 26.7916452187 16712894 17306315
MESH:D001749 Urinary Bladder Neoplasms Raloxifene 26.7917572228
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 26.7916712894 16452187 17306315 11723127
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 26.7916712894 17572228 8653321
MESH:D001749 Urinary Bladder Neoplasms Tobacco Smoke Pollution 26.7912846360
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 3.6510091137
MESH:D014581 Urticaria Acetaminophen 2.3710982225
MESH:D002583 Uterine Cervical Neoplasms Cisplatin 17.9016803524
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 17.9016175088
MESH:D002583 Uterine Cervical Neoplasms resveratrol 17.9017473185
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 17.9011813266
MESH:D014591 Uterine Diseases Diethylstilbestrol 4.4914652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 17.8415809267 16690809
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 17.8414692618
MESH:D014594 Uterine Neoplasms Ethylene Oxide 17.8417325976 12562636
MESH:D014594 Uterine Neoplasms resveratrol 17.8417044934
MESH:D014625 Vaginal Neoplasms Cisplatin 14.9115577323
MESH:D014625 Vaginal Neoplasms Dacarbazine 14.9115577323
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 14.9116513791 16002989
MESH:D014652 Vascular Diseases Arsenic 9.6417056641
MESH:D014652 Vascular Diseases sodium arsenite 9.6417056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 3.9212125929
MESH:D054556 Venous Thromboembolism Raloxifene 4.5316837676
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 2.9414671159 15869587
MESH:D018487 Ventricular Dysfunction, Left resveratrol 3.6617488730
MESH:D014839 Vomiting Cisplatin 4.0411897121
MESH:D014846 Vulvar Neoplasms Raloxifene 4.8816343187
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.5715886252
Pathway ID Pathway Name
KEGG:03410 Base excision repair
REACT:216 DNA Repair
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA201059
    • No data
    Releated disease ID Related disease Name
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    PA446171Leukemia, Myelogenous, Chronic, BCR-ABL Positive
    Releated drug ID Related drug Name
    PA448691busulfan
    PA450379mercaptopurine
    PA450428methotrexate
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB04967 antagonist Lucanthone Radiation-Sensitizing Agents;Anticancer Agents;Schistosomicides
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


    Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved