AutismKB 2.0

Annotation Detail for BIRC2


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Basic Information Top
Gene Symbol:BIRC2 ( API1,HIAP2,Hiap-2,MIHB,RNF48,c-IAP1,cIAP1 )
Gene Full Name: baculoviral IAP repeat-containing 2
Band: 11q22.2
Quick LinksEntrez ID:329; OMIM: 601712; Uniprot ID:BIRC2_HUMAN; ENSEMBL ID: ENSG00000110330; HGNC ID: 590
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa05145Toxoplasmosis
hsa04621NOD-like receptor signaling pathway
hsa04120Ubiquitin mediated proteolysis
hsa05222Small cell lung cancer
hsa04510Focal adhesion
hsa04210Apoptosis
hsa05200Pathways in cancer
Pathway IDPathway Name
Apoptosis
Pathway IDPathway Name
200031CD40/CD40L signaling
200086TNF receptor signaling pathway
200148Caspase cascade in apoptosis
200026Canonical NF-kappaB pathway
Pathway IDPathway Name
P00006Apoptosis signaling pathway
Pathway IDPathway Name
500270Apoptotic cleavage of cellular proteins
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1877Multiple sclerosis
1934Cancer
2069Schizophrenia
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C097240 15-deoxy-delta(12,14)-prostaglandin J2 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of BIRC2 proteindecreases expression 15498850
C477819 15-deoxyprostaglandin J2 15-deoxyprostaglandin J2 results in decreased degradation of and results in increased stability of and results in increased expression of BIRC2 proteindecreases degradation|increases expression|increases stability 12623786
C047948 1'-acetoxychavicol acetate 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased expression of BIRC2 protein]decreases reaction|increases expression 15905586
C477931 1L-6-hydroxymethyl-chiro-inositol 2(R)-2-O-methyl-3-O-octadecylcarbonate 1L-6-hydroxymethyl-chiro-inositol 2(R)-2-O-methyl-3-O-octadecylcarbonate results in decreased expression of BIRC2 proteindecreases expression 12970779
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of BIRC2 mRNAaffects expression 21346803
C085911 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Acrolein results in increased expression of BIRC2 protein]decreases reaction|increases expression 19596284
C085911 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased expression of BIRC2 mRNAdecreases expression 15065019
C085911 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased expression of BIRC2 proteindecreases expression 12970779
15065019
14762343
C085911 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Butyrates results in increased expression of BIRC2 mRNA]decreases reaction|increases expression 16256798
C501280 2-amino-6-(2-(cyclopropylmethoxy)-6-hydroxyphenyl)-4-piperidin-4-yl nicotinonitrile 2-amino-6-(2-(cyclopropylmethoxy)-6-hydroxyphenyl)-4-piperidin-4-yl nicotinonitrile results in decreased expression of BIRC2 mRNAdecreases expression 15756023
C434003 3-(4-methylphenylsulfonyl)-2-propenenitrile 3-(4-methylphenylsulfonyl)-2-propenenitrile results in decreased expression of BIRC2 mRNAdecreases expression 16380446
C106592 3,9-bis((ethylthio)methyl)-K-252a 3,9-bis((ethylthio)methyl)-K-252a results in increased expression of BIRC2 mRNAincreases expression 15294995
C480030 4-(3-(1-adamantyl)-4-hydroxyphenyl)-3-chlorocinnamic acid 4-(3-(1-adamantyl)-4-hydroxyphenyl)-3-chlorocinnamic acid results in decreased expression of BIRC2 proteindecreases expression 15930313
D000082 Acetaminophen Acetaminophen affects the expression of BIRC2 mRNAaffects expression 17562736
C011157 aclacinomycins aclacinomycins results in decreased expression of BIRC2 mRNAdecreases expression 15498119
D000171 Acrolein 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Acrolein results in increased expression of BIRC2 protein]decreases reaction|increases expression 19596284
D000171 Acrolein Acrolein results in increased expression of BIRC2 proteinincreases expression 19596284
D000171 Acrolein Akt-I-1 compound inhibits the reaction [Acrolein results in increased expression of BIRC2 protein]decreases reaction|increases expression 19596284
D000171 Acrolein wortmannin inhibits the reaction [Acrolein results in increased expression of BIRC2 protein]decreases reaction|increases expression 19596284
C501520 Akt-I-1 compound Akt-I-1 compound inhibits the reaction [Acrolein results in increased expression of BIRC2 protein]decreases reaction|increases expression 19596284
D000643 Ammonium Chloride Ammonium Chloride affects the expression of BIRC2 mRNAaffects expression 16483693
C432165 anthra(1,9-cd)pyrazol-6(2H)-one anthra(1,9-cd)pyrazol-6(2H)-one promotes the reaction [IL1A protein results in increased expression of BIRC2 mRNA]increases expression|increases reaction 12832416
C015001 arsenite arsenite results in increased expression of BIRC2 mRNAincreases expression 18585952
C015001 arsenite XPA protein affects the reaction [arsenite results in increased expression of BIRC2 mRNA]affects reaction|increases expression 18585952
C015001 arsenite arsenite results in decreased expression of BIRC2 mRNAdecreases expression 18191166
C001758 bendamustine bendamustine results in decreased expression of BIRC2 proteindecreases expression 15359644
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of BIRC2 mRNAdecreases expression 19150397
D001761 Bleomycin BIRC2 protein results in decreased susceptibility to Bleomycindecreases response to substance 10815900
D001761 Bleomycin Bleomycin results in increased expression of BIRC2 proteinincreases expression 15371238
C400082 bortezomib bortezomib results in decreased expression of BIRC2 proteindecreases expression 15543232
C400082 bortezomib [geldanamycin co-treated with bortezomib] results in decreased expression of BIRC2 proteinaffects cotreatment|decreases expression 15781649
D002087 Butyrates 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Butyrates results in increased expression of BIRC2 mRNA]decreases reaction|increases expression 16256798
D002087 Butyrates Butyrates results in increased expression of BIRC2 mRNAincreases expression 16256798
D002104 Cadmium Cadmium results in increased expression of BIRC2 proteinincreases expression 14647439
D002104 Cadmium Cadmium results in decreased expression of BIRC2 proteindecreases expression 16478757
D019256 Cadmium Chloride Cadmium Chloride results in decreased expression of BIRC2 proteindecreases expression 16478757
C055494 caffeic acid phenethyl ester caffeic acid phenethyl ester results in decreased expression of BIRC2 proteindecreases expression 15291876
D002251 Carbon Tetrachloride [Carbon Tetrachloride co-treated with Folic Acid] results in decreased expression of BIRC2 mRNAaffects cotreatment|decreases expression 18156304
C469298 CEP-11004 CEP-11004 results in increased expression of BIRC2 mRNAincreases expression 15294995
D002699 Chlorambucil BIRC2 protein results in decreased susceptibility to Chlorambucildecreases response to substance 10815900
C012843 cinnamic aldehyde cinnamic aldehyde results in decreased expression of BIRC2 proteindecreases expression 15566391
C012843 cinnamic aldehyde Vitamin E inhibits the reaction [cinnamic aldehyde results in decreased expression of BIRC2 protein]decreases expression|decreases reaction 15566391
D003474 Curcumin Curcumin analog results in decreased expression of BIRC2 mRNAdecreases expression 17671737
D003474 Curcumin Curcumin inhibits the reaction [Paclitaxel results in increased expression of BIRC2 protein]decreases reaction|increases expression 16243823
D003474 Curcumin Curcumin inhibits the reaction [TNF protein results in increased expression of BIRC2 mRNA]decreases reaction|increases expression 16219905
D003474 Curcumin Curcumin inhibits the reaction [TNF protein results in increased expression of BIRC2 protein]decreases reaction|increases expression 17640567
D003474 Curcumin Curcumin results in decreased expression of BIRC2 mRNAdecreases expression 17596214
17671737
D003474 Curcumin Curcumin results in decreased expression of BIRC2 proteindecreases expression 16023083
D003474 Curcumin Glutathione inhibits the reaction [Curcumin inhibits the reaction [TNF protein results in increased expression of BIRC2 protein]]decreases reaction|increases expression 17640567
D016572 Cyclosporine Cyclosporine results in increased expression of BIRC2 mRNAincreases expression 20106945
C014347 decitabine decitabine affects the expression of BIRC2 proteinaffects expression 18636160
C464444 dehydroxymethylepoxyquinomicin dehydroxymethylepoxyquinomicin results in decreased expression of BIRC2 proteindecreases expression 15501958
C075597 Dendroaspis natriuretic peptide Dendroaspis natriuretic peptide results in decreased expression of BIRC2 proteindecreases expression 15803858
D016190 Carboplatin BIRC2 protein results in decreased susceptibility to Carboplatindecreases response to substance 10815900
D002945 Cisplatin BIRC2 protein results in decreased susceptibility to Cisplatindecreases response to substance 14654915
16142363
10815900
C499970 dideoxypetrosynol A dideoxypetrosynol A results in decreased expression of BIRC2 proteindecreases expression 15547680
D002117 Calcitriol Calcitriol results in decreased expression of BIRC2 proteindecreases expression 12479363
D004144 Diosgenin Diosgenin inhibits the reaction [TNF protein results in increased expression of BIRC2 protein]decreases reaction|increases expression 16331273
D004144 Diosgenin Diosgenin results in decreased expression of BIRC2 proteindecreases expression 16331273
D004317 Doxorubicin BIRC2 protein affects the susceptibility to Doxorubicinaffects response to substance 16217747
14666661
D004317 Doxorubicin Doxorubicin results in decreased expression of BIRC2 proteindecreases expression 15359644
D004317 Doxorubicin Doxorubicin results in increased expression of BIRC2 mRNAincreases expression 17521628
D004317 Doxorubicin Doxorubicin results in increased expression of BIRC2 proteinincreases expression 14666661
15571967
D004317 Doxorubicin Sirolimus inhibits the reaction [Doxorubicin results in increased expression of BIRC2 protein]decreases reaction|increases expression 15571967
D004958 Estradiol Estradiol affects the expression of BIRC2 mRNAaffects expression 15598610
D017308 Etodolac Etodolac results in decreased expression of BIRC2 proteindecreases expression 16104877
D017308 Etodolac Etodolac results in increased activity of BIRC2 proteinincreases activity 16046235
D005047 Etoposide BIRC2 protein affects the susceptibility to Etoposideaffects response to substance 16217747
D005047 Etoposide BIRC2 protein results in decreased susceptibility to Etoposidedecreases response to substance 15050749
10815900
D005047 Etoposide Etoposide results in increased expression of BIRC2 mRNAincreases expression 14970392
C049639 evodiamine evodiamine inhibits the reaction [TNF protein results in increased expression of BIRC2 protein]decreases reaction|increases expression 15710601
D005419 Flavonoids Flavonoids results in decreased expression of BIRC2 mRNAdecreases expression 18035473
D005472 Fluorouracil Fluorouracil results in increased expression of BIRC2 mRNAincreases expression 17039268
D005492 Folic Acid Folic Acid results in increased expression of BIRC2 mRNAincreases expression 15211800
D005492 Folic Acid Folic Acid results in increased expression of BIRC2 proteinincreases expression 15211800
D005492 Folic Acid [Carbon Tetrachloride co-treated with Folic Acid] results in decreased expression of BIRC2 mRNAaffects cotreatment|decreases expression 18156304
C007789 fucoidan fucoidan results in decreased expression of BIRC2 proteindecreases expression 16201850
D005665 Furosemide Furosemide affects the expression of BIRC2 mRNAaffects expression 17497460
C001277 geldanamycin [geldanamycin co-treated with bortezomib] results in decreased expression of BIRC2 proteinaffects cotreatment|decreases expression 15781649
C056507 gemcitabine gemcitabine results in increased expression of BIRC2 mRNAincreases expression 17039268
D005978 Glutathione Glutathione inhibits the reaction [Curcumin inhibits the reaction [TNF protein results in increased expression of BIRC2 protein]]decreases reaction|increases expression 17640567
D006427 Hemin Hemin results in increased expression of BIRC2 proteinincreases expression 14647439
D017313 Fenretinide Fenretinide inhibits the reaction BIRC2 proteindecreases reaction 16230421
D017313 Fenretinide Fenretinide inhibits the reaction [TNF protein results in increased expression of BIRC2 protein]decreases reaction|increases expression 16230421
C097613 imatinib [tetraarsenic tetrasulfide co-treated with imatinib] results in decreased expression of BIRC2 mRNAaffects cotreatment|decreases expression 19208803
C016517 indole-3-carbinol indole-3-carbinol inhibits the reaction [TNF protein results in increased expression of BIRC2 protein]decreases reaction|increases expression 15811958
C506002 ircinin-1 ircinin-1 results in decreased expression of BIRC2 mRNAdecreases expression 16163705
C506002 ircinin-1 ircinin-1 results in decreased expression of BIRC2 proteindecreases expression 16163705
C051890 irinotecan irinotecan results in increased expression of BIRC2increases expression 15161687
C040920 isoliquiritigenin isoliquiritigenin results in decreased expression of BIRC2 proteindecreases expression 15729620
C047382 kamebakaurin kamebakaurin inhibits the reaction [TNF protein results in increased expression of BIRC2 protein]decreases reaction|increases expression 11877450
C011890 kojic acid kojic acid results in decreased expression of BIRC2 mRNAdecreases expression 16595896
C038753 leptomycin B leptomycin B affects the localization of BIRC2 proteinaffects localization 15265700
C000654 leucine sarcolysine BIRC2 protein results in decreased susceptibility to leucine sarcolysinedecreases response to substance 10815900
C115354 lonafarnib lonafarnib inhibits the reaction [TNF protein results in increased expression of BIRC2 protein]decreases reaction|increases expression 15090542
D047311 Luteolin Luteolin inhibits the reaction [TNF protein results in increased expression of BIRC2 protein]decreases reaction|increases expression 15334063
C002950 methylformamide methylformamide analog results in decreased expression of BIRC2 mRNAdecreases expression 17040096
C002950 methylformamide methylformamide results in decreased expression of BIRC2 mRNAdecreases expression 17040096
D008769 Methylnitronitrosoguanidine Methylnitronitrosoguanidine results in increased expression of BIRC2 mRNAincreases expression 12634122
C008493 methylselenic acid methylselenic acid affects the expression of BIRC2 mRNAaffects expression 14617803
D016685 Mitomycin BIRC2 protein affects the susceptibility to Mitomycinaffects response to substance 16217747
D008942 Mitoxantrone Mitoxantrone results in decreased expression of BIRC2 proteindecreases expression 15359644
C058815 N-(2-aminoethyl)-5-chloroisoquinoline-8-sulfonamide N-(2-aminoethyl)-5-chloroisoquinoline-8-sulfonamide promotes the reaction [TNFSF10 protein results in increased expression of BIRC2 protein]increases expression|increases reaction 15520213
C029938 nickel sulfate nickel sulfate results in increased expression of BIRC2 mRNAincreases expression 16780908
D009569 Nitric Oxide Nitric Oxide results in increased expression of BIRC2 proteinincreases expression 14634119
D017239 Paclitaxel BIRC2 protein affects the susceptibility to Paclitaxelaffects response to substance 16217747
D017239 Paclitaxel Curcumin inhibits the reaction [Paclitaxel results in increased expression of BIRC2 protein]decreases reaction|increases expression 16243823
D017239 Paclitaxel Paclitaxel results in decreased expression of BIRC2 proteindecreases expression 14749477
D010936 Plant Extracts Plant Extracts affects the expression of BIRC2 mRNAaffects expression 12878215
D010936 Plant Extracts Plant Extracts inhibits the reaction [TNF protein results in increased expression of BIRC2 protein]decreases reaction|increases expression 18841906
D011188 Potassium BIRC2 protein affects the susceptibility to Potassiumaffects response to substance 9886081
C023617 pregna-4,17-diene-3,16-dione pregna-4,17-diene-3,16-dione inhibits the reaction [TNF protein results in increased expression of BIRC2 mRNA]decreases reaction|increases expression 15322087
C059514 resveratrol resveratrol results in increased expression of BIRC2 mRNAincreases expression 12569576
D012643 Selenium [Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of BIRC2 mRNAaffects cotreatment|decreases expression 11444866
D012673 Semustine BIRC2 protein results in decreased susceptibility to Semustinedecreases response to substance 10815900
D020123 Sirolimus Sirolimus inhibits the reaction [Doxorubicin results in increased expression of BIRC2 protein]decreases reaction|increases expression 15571967
C025473 sitosterol sitosterol results in decreased expression of BIRC2 proteindecreases expression 14612938
C118258 SN50 peptide SN50 peptide results in decreased expression of BIRC2 proteindecreases expression 12970779
C017947 sodium arsenite sodium arsenite results in increased expression of BIRC2 mRNAincreases expression 14970392
D018038 Sodium Selenite Sodium Selenite results in increased expression of BIRC2 mRNAincreases expression 16705456
D018038 Sodium Selenite Sodium Selenite results in decreased expression of BIRC2 proteindecreases expression 14737004
C480848 tephrosin tephrosin inhibits the reaction [TNF protein results in increased expression of BIRC2 protein]decreases reaction|increases expression 18841906
C534735 tetraarsenic tetrasulfide [tetraarsenic tetrasulfide co-treated with imatinib] results in decreased expression of BIRC2 mRNAaffects cotreatment|decreases expression 19208803
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of BIRC2 mRNAincreases expression 12167310
D013755 Tetradecanoylphorbol Acetate Tetradecanoylphorbol Acetate affects the localization of BIRC2 proteinaffects localization 15187025
D019284 Thapsigargin Thapsigargin results in decreased expression of BIRC2 proteindecreases expression 16382148
D013866 Thioguanine BIRC2 protein results in decreased susceptibility to Thioguaninedecreases response to substance 10815900
D013876 Thiophenes Thiophenes analog promotes the reaction [Tretinoin results in increased expression of BIRC2 mRNA]increases expression|increases reaction 16140955
D019772 Topotecan BIRC2 protein affects the susceptibility to Topotecanaffects response to substance 16217747
D014212 Tretinoin Thiophenes analog promotes the reaction [Tretinoin results in increased expression of BIRC2 mRNA]increases expression|increases reaction 16140955
D014212 Tretinoin [Tretinoin co-treated with zoledronic acid] results in decreased expression of BIRC2 mRNAaffects cotreatment|decreases expression 20349282
D014212 Tretinoin Tretinoin results in increased expression of BIRC2 mRNAincreases expression 16140955
D014212 Tretinoin Tretinoin results in decreased expression of BIRC2 mRNAdecreases expression 16604517
C501517 UCF 101 UCF 101 results in decreased degradation of BIRC2 proteindecreases degradation 15967379
D014747 Vinblastine BIRC2 protein affects the susceptibility to Vinblastineaffects response to substance 16217747
D014810 Vitamin E Vitamin E inhibits the reaction [cinnamic aldehyde results in decreased expression of BIRC2 protein]decreases expression|decreases reaction 15566391
D014810 Vitamin E [Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of BIRC2 mRNAaffects cotreatment|decreases expression 11444866
C111237 vorinostat vorinostat inhibits the reaction [TNF protein results in increased expression of BIRC2 mRNA]decreases reaction|increases expression 16377638
C009687 wortmannin wortmannin inhibits the reaction [Acrolein results in increased expression of BIRC2 protein]decreases reaction|increases expression 19596284
C009687 wortmannin wortmannin results in decreased expression of BIRC2 mRNAdecreases expression 15065019
C009687 wortmannin wortmannin results in decreased expression of BIRC2 proteindecreases expression 15065019
C403304 zerumbone zerumbone results in decreased expression of BIRC2 mRNAdecreases expression 16007145
C088658 zoledronic acid [Tretinoin co-treated with zoledronic acid] results in decreased expression of BIRC2 mRNAaffects cotreatment|decreases expression 20349282
C088658 zoledronic acid zoledronic acid results in decreased expression of BIRC2 mRNAdecreases expression 19036117
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.0114514962 11752688 15322242
MESH:D000015 Abnormalities, Multiple imatinib 4.4618322153
MESH:D000022 Abortion, Spontaneous imatinib 5.3218322153
MESH:D000138 Acidosis Ammonium Chloride 2.6918287403
MESH:D058186 Acute Kidney Injury Cisplatin 14.1412690470 15814532 17670903
MESH:D058186 Acute Kidney Injury Folic Acid 14.1416316344 17003819 16595132
MESH:D058186 Acute Kidney Injury resveratrol 14.1416538975
MESH:D058186 Acute Kidney Injury zoledronic acid 14.1419715164
MESH:D055371 Acute Lung Injury Acrolein 10.9821297076 20525806
MESH:D055371 Acute Lung Injury Bleomycin 10.9817118201
MESH:D055371 Acute Lung Injury nickel sulfate 10.9811954676 12718980 19131640 16100012
MESH:D000210 Acute-Phase Reaction zoledronic acid 4.6120200999
MESH:D000230 Adenocarcinoma Cisplatin 10.0111798837 17638652
MESH:D000230 Adenocarcinoma Doxorubicin 10.0117418594
MESH:D000230 Adenocarcinoma Estradiol 10.0111473722
MESH:D000230 Adenocarcinoma Fenretinide 10.0110697514
MESH:D000230 Adenocarcinoma Fluorouracil 10.0117638652
MESH:D000236 Adenoma Folic Acid 5.2816963246
MESH:D000236 Adenoma resveratrol 5.2815688382
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 2.5116835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 3.8115276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.0117306315 16712894
MESH:D000419 Albuminuria Doxorubicin 3.7121441931
MESH:D019973 Alcohol-Related Disorders Curcumin 4.1917887948
OMIM:607154 ALLERGIC RHINITIS Etodolac 5.0016979129
MESH:D000505 Alopecia Tretinoin 2.8915955085
MESH:D000544 Alzheimer Disease Acrolein 11.8317570602 14715435 15207723
MESH:D000544 Alzheimer Disease Curcumin 11.8315590663
MESH:D000544 Alzheimer Disease Folic Acid 11.8317116317
MESH:D000544 Alzheimer Disease Nitric Oxide 11.8317556102
MESH:D000544 Alzheimer Disease Plant Extracts 11.8316962711
MESH:D000544 Alzheimer Disease resveratrol 11.8316183991 16162502
MESH:D000740 Anemia Fluorouracil 6.1216511603 17963324 15504547
MESH:D000740 Anemia Tetrachlorodibenzodioxin 6.1211748828
MESH:D000799 Angioedema Acetaminophen 2.9610982225
MESH:D000860 Anoxia Bleomycin 4.5415782499
MESH:D001161 Arteriosclerosis Acrolein 4.1615014928
MESH:D001169 Arthritis, Experimental Plant Extracts 8.9014686799
MESH:D001169 Arthritis, Experimental resveratrol 8.9017115116
MESH:D001169 Arthritis, Experimental Tretinoin 8.9016412693
MESH:D001172 Arthritis, Rheumatoid Curcumin 3.7016807698
MESH:D001172 Arthritis, Rheumatoid Tretinoin 3.7016292516
MESH:D001249 Asthma Tretinoin 2.0116456186
MESH:D050197 Atherosclerosis Acrolein 10.8717363696 16126721 16037261
MESH:D050197 Atherosclerosis Cadmium 10.8715687053
MESH:D050197 Atherosclerosis Curcumin 10.8718704882
MESH:D050197 Atherosclerosis resveratrol 10.8716873680 17967414
MESH:D001321 Autistic Disorder Acetaminophen 2.3018445737
MESH:D001321 Autistic Disorder Folic Acid 2.3021388746
MESH:D001321 Autistic Disorder Glutathione 2.3016917939 19267885 19056591 18929414
MESH:D001321 Autistic Disorder Sirolimus 2.3021115397
MESH:D001327 Autoimmune Diseases Curcumin 3.6419761891
MESH:D001471 Barrett Esophagus Tretinoin 3.5616935849
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 6.3112125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 6.3116206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 2.9015340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.1415746008
MESH:D019046 Bone Marrow Neoplasms Cisplatin 15.2714601052
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 15.2714601052
MESH:D019046 Bone Marrow Neoplasms Etoposide 15.2714601052
MESH:D001859 Bone Neoplasms imatinib 13.0415867366
MESH:D001859 Bone Neoplasms Paclitaxel 13.0415867366
MESH:D001859 Bone Neoplasms zoledronic acid 13.0417312309 19442620 15867366 16121404 11697798 16778634
MESH:D001862 Bone Resorption zoledronic acid 3.9116769263 18404659 11869084 18496637 15845617 8053405
MESH:D002545 Brain Ischemia Curcumin 12.1416770732
MESH:D002545 Brain Ischemia Plant Extracts 12.1416041641
MESH:D002545 Brain Ischemia resveratrol 12.1417600658
MESH:D001932 Brain Neoplasms Curcumin 10.3317596214
MESH:D001932 Brain Neoplasms Doxorubicin 10.3317150277
MESH:D001932 Brain Neoplasms Fenretinide 10.3316187019
MESH:D001943 Breast Neoplasms bendamustine 20.7617667603
MESH:D001943 Breast Neoplasms Calcitriol 20.7611237771
MESH:D001943 Breast Neoplasms Cisplatin 20.7619526202 18382427
MESH:D001943 Breast Neoplasms Curcumin 20.7616243823 18593918 19250217 18462866
MESH:D001943 Breast Neoplasms decitabine 20.7618320071 19208741
MESH:D001943 Breast Neoplasms Doxorubicin 20.7618234424 16264153 16115903 15939500 19526202 18695136 16595493 16096432 15567936 18628466 15692762 15993339 16826403 15994142 16935488 18382427 15634643 15668708 11325840 17369602 16322301 17426702 17983394 15136595
MESH:D001943 Breast Neoplasms Estradiol 20.7617289903 16675129 12948864 18497071 17018787 14630087 17261762 19861407
MESH:D001943 Breast Neoplasms Etoposide 20.7616322251
MESH:D001943 Breast Neoplasms Fenretinide 20.7616601279
MESH:D001943 Breast Neoplasms Fluorouracil 20.7616110121 15136595 18357371 16595493 19217205 18608205 16557594
MESH:D001943 Breast Neoplasms Folic Acid 20.7616777985
MESH:D001943 Breast Neoplasms gemcitabine 20.7618382427 17039268
MESH:D001943 Breast Neoplasms imatinib 20.7617614352
MESH:D001943 Breast Neoplasms indole-3-carbinol 20.7616082211
MESH:D001943 Breast Neoplasms Nitric Oxide 20.7615631943
MESH:D001943 Breast Neoplasms Paclitaxel 20.7618234424 16115903 18223236 11325840 16244791 16273361 15136595 18323546
MESH:D001943 Breast Neoplasms resveratrol 20.7616393696 17651959 17534123
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 20.7620435547
MESH:D001943 Breast Neoplasms Tretinoin 20.7616166294 16443354 16873071
MESH:D001943 Breast Neoplasms vorinostat 20.7616144943
MESH:D001943 Breast Neoplasms zoledronic acid 20.7618695136 16096432
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 3.7216813970
MESH:D002057 Burns, Chemical Plant Extracts 4.459625245
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 3.5916111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 7.1116124888 18705752 16097048 15700767 10355542 15721981 3786805 15673190 16192424 16227642 16050911 16011737
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 7.1116050911
MESH:D002276 Carcinoid Tumor Doxorubicin 9.4116051944
MESH:D002276 Carcinoid Tumor Fluorouracil 9.4116051944
MESH:D002277 Carcinoma Curcumin 9.8018593918
MESH:D002277 Carcinoma Fluorouracil 9.8017121937
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 9.8016835633
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.2716168501
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 31.6816705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 31.683084413
MESH:D006528 Carcinoma, Hepatocellular anthra(1,9-cd)pyrazol-6(2H)-one 31.6819418558
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 31.6818788625
MESH:D006528 Carcinoma, Hepatocellular Cisplatin 31.6817982673
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 31.6818059187 16234567 16023760 17876044
MESH:D006528 Carcinoma, Hepatocellular Estradiol 31.6816924424
MESH:D006528 Carcinoma, Hepatocellular Fenretinide 31.6817159502 16270382
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 31.6818930000 17971768 17088986 17045692 16332177 16799960
MESH:D006528 Carcinoma, Hepatocellular Paclitaxel 31.6816313753
MESH:D006528 Carcinoma, Hepatocellular Plant Extracts 31.6818834353
MESH:D006528 Carcinoma, Hepatocellular resveratrol 31.6819321006 16227395
MESH:D006528 Carcinoma, Hepatocellular Sirolimus 31.6819335982
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 31.6817306315 15276417 16507464
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 31.681917145
MESH:D018827 Carcinoma, Lewis Lung resveratrol 3.7216675471
MESH:D002289 Carcinoma, Non-Small-Cell Lung bortezomib 12.4416052434
MESH:D002289 Carcinoma, Non-Small-Cell Lung Carboplatin 12.4416685392
MESH:D002289 Carcinoma, Non-Small-Cell Lung Cisplatin 12.4416685392 12023789
MESH:D002289 Carcinoma, Non-Small-Cell Lung Curcumin 12.4418414057
MESH:D002289 Carcinoma, Non-Small-Cell Lung zoledronic acid 12.4419233551
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 11.271485588 16201981
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 11.2718695887
MESH:D002292 Carcinoma, Renal Cell Vinblastine 11.271485588
MESH:D002292 Carcinoma, Renal Cell zoledronic acid 11.2718507039
MESH:D002294 Carcinoma, Squamous Cell Bleomycin 41.346189445
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 41.3411237771
MESH:D002294 Carcinoma, Squamous Cell Cisplatin 41.346189445 17066447 18337622
MESH:D002294 Carcinoma, Squamous Cell Curcumin 41.3418462866
MESH:D002294 Carcinoma, Squamous Cell decitabine 41.3419215824
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 41.346189445
MESH:D002294 Carcinoma, Squamous Cell Fenretinide 41.3416274795
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 41.3416757204 16280240 17066447 18986760
MESH:D002294 Carcinoma, Squamous Cell Glutathione 41.3417015178
MESH:D002294 Carcinoma, Squamous Cell resveratrol 41.3416227395
MESH:D002294 Carcinoma, Squamous Cell Sirolimus 41.3419435901
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 41.3418572023
MESH:D002294 Carcinoma, Squamous Cell Tetradecanoylphorbol Acetate 41.3418922899
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 41.3416051514 16096774
MESH:D006332 Cardiomegaly Plant Extracts 5.0917645561
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 5.0918670907 16120746 18850075
MESH:D009202 Cardiomyopathies Doxorubicin 2.9017007740 16612575 17928571 16364871 16455267 17308081 16952015 17519947 16278810 17329180 16242529 16731534 17924179 16651473 17974986 17131338 15505089 15476868 17382496 18627295 15792986 16109756 17351982 16269455 15811867
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.5616243910 17334414
MESH:D002318 Cardiovascular Diseases Folic Acid 5.5716755160
MESH:D002318 Cardiovascular Diseases resveratrol 5.5715458977
MESH:D002386 Cataract Acetaminophen 5.2510977129
MESH:D002386 Cataract Tretinoin 5.2517460283
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 21.8420889678
MESH:D002471 Cell Transformation, Neoplastic Cadmium 21.8417332340
MESH:D002471 Cell Transformation, Neoplastic cinnamic aldehyde 21.848243401
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 21.8412371664
MESH:D002471 Cell Transformation, Neoplastic Estradiol 21.8418566989
MESH:D002471 Cell Transformation, Neoplastic Methylnitronitrosoguanidine 21.842727394
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 21.8420056578 19524636
MESH:D018290 Cervical Intraepithelial Neoplasia Fenretinide 10.0816154183
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 10.0816129372
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 2.4016835633
MESH:D002779 Cholestasis Cyclosporine 9.8819486331
MESH:D002779 Cholestasis Diosgenin 9.8816105132
MESH:D002779 Cholestasis Nitric Oxide 9.8816919318
MESH:D002822 Choriocarcinoma Tretinoin 4.2716461808
MESH:D019457 Chromosome Breakage Sodium Selenite 3.8915894690
MESH:D002971 Cleft Lip Folic Acid 3.4421254359
MESH:D002972 Cleft Palate Folic Acid 7.168946559 21254359
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 7.1615668235 12621046 8697196 16354765 15340226
MESH:D002972 Cleft Palate Tretinoin 7.169407595
MESH:D003092 Colitis Curcumin 15.9318200517 16804969 16782535
MESH:D003092 Colitis resveratrol 15.9316474422
MESH:D003092 Colitis Selenium 15.9317936198
MESH:D003092 Colitis Tretinoin 15.9317035595
MESH:D003103 Coloboma Curcumin 3.7518809619
MESH:D003110 Colonic Neoplasms arsenite 18.6215037631
MESH:D003110 Colonic Neoplasms Butyrates 18.6215936596
MESH:D003110 Colonic Neoplasms cinnamic aldehyde 18.6216343908 17510524
MESH:D003110 Colonic Neoplasms Curcumin 18.6219359593 16340194
MESH:D003110 Colonic Neoplasms decitabine 18.6217616700
MESH:D003110 Colonic Neoplasms Etodolac 18.6216004971
MESH:D003110 Colonic Neoplasms Fluorouracil 18.6217172411 16510598 18772588 15001691 17169374 17725105 17287894 16340194 17016597 17018589
MESH:D003110 Colonic Neoplasms irinotecan 18.6217725105 17287894
MESH:D003110 Colonic Neoplasms resveratrol 18.6216338953
MESH:D015179 Colorectal Neoplasms Acrolein 18.5517597105
MESH:D015179 Colorectal Neoplasms Cisplatin 18.5515273666
MESH:D015179 Colorectal Neoplasms decitabine 18.5518981723
MESH:D015179 Colorectal Neoplasms Doxorubicin 18.5518802399 18259882
MESH:D015179 Colorectal Neoplasms Etodolac 18.5511076880
MESH:D015179 Colorectal Neoplasms Fenretinide 18.5517273769
MESH:D015179 Colorectal Neoplasms Fluorouracil 18.5517094418 18802399 17016601 16282729 16391804 17454858 15289873 16524972 17255274 16303861 18288408 18509181 18448328 17401013 17594712 18383874 16331619 17695437 18949393 20501625 14970324 15148649
MESH:D015179 Colorectal Neoplasms Folic Acid 18.5517087956 16985020 16963246 17116713 17245555
MESH:D015179 Colorectal Neoplasms irinotecan 18.5516391804 15273666 17159606 17454858 18259882 18509181 16303861
MESH:D015179 Colorectal Neoplasms Paclitaxel 18.5518802399
MESH:D015179 Colorectal Neoplasms resveratrol 18.5516550006
MESH:D015179 Colorectal Neoplasms Vinblastine 18.5518802399
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.3014669216 17141729
MESH:D016510 Corneal Neovascularization Curcumin 4.0418497527
MESH:D003327 Coronary Disease resveratrol 3.1316507316
MESH:D019465 Craniofacial Abnormalities imatinib 4.1218322153
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 4.1210048152 20055451 15322242
MESH:D019465 Craniofacial Abnormalities Tretinoin 4.129142499 9125849 8800419 9664655 9211117 14991402 16925845 10589399 9224671 17551590
MESH:D019465 Craniofacial Abnormalities Vitamin E 4.1219769572
MESH:D003490 Cyanosis 2,4-dinitrotoluene 3.1618551238
MESH:D003550 Cystic Fibrosis Glutathione 3.7319747007
MESH:D003556 Cystitis Acrolein 4.5112161096
MESH:D007644 Darier Disease Fluorouracil 3.9216733453
MESH:D015140 Dementia, Vascular Nitric Oxide 5.0817556102
MESH:D017449 Dermatitis, Allergic Contact cinnamic aldehyde 5.0911042091
MESH:D017449 Dermatitis, Allergic Contact nickel sulfate 5.0916780908 11298694 16823706
MESH:D003920 Diabetes Mellitus Sodium Selenite 3.0216285004
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 3.0416873680
MESH:D003924 Diabetes Mellitus, Type 2 Curcumin 5.3718403477
MESH:D003924 Diabetes Mellitus, Type 2 Folic Acid 5.3716886840
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 5.3717107852
MESH:D003928 Diabetic Nephropathies Curcumin 15.3118204486
MESH:D003928 Diabetic Nephropathies Estradiol 15.3119279558
MESH:D003928 Diabetic Nephropathies Plant Extracts 15.3119706694
MESH:D003928 Diabetic Nephropathies resveratrol 15.3116286809
MESH:D003967 Diarrhea vorinostat 3.7020479100
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 12.9518551238 21346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 12.9516227642 14725611 17906064 16781746 17522070 11739529 15968718 12705907 2444490 19416960 10915739 11743745 19164858 14550746 11421492 12540782 11287661 11461765 19420014 18071297 11834606 12392966 14986274 16393943 12958197 17562736 19739265 10663392 16081117 19370779 12594235 16485898 19085960 12153990 16109766 10774834 16177239 18713872 19923254 11529661 15619225
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 12.9511566570 7179309 3732212 10092053 6623471 2869522 15998439 10915739 4309450 16227642 16177239 9327722 17522070 6884620 3786805 21278145 19085960 15027814 7440962 15968718 7120509 19336974
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 12.9517416283
MESH:D056486 Drug-Induced Liver Injury Selenium 12.9515131321
MESH:D056486 Drug-Induced Liver Injury Sodium Selenite 12.9515131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 12.9520420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.2119426721
MESH:D004362 Drug Toxicity Cisplatin 9.7719839026 15033597 12649298 12231392
MESH:D004362 Drug Toxicity Doxorubicin 9.7718602426
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 9.7711462148
MESH:D004381 Duodenal Ulcer Curcumin 3.2317351913
MESH:D004417 Dyspnea Furosemide 4.0616935035
MESH:C538011 Eales disease Vitamin E 3.829068938
MESH:D004487 Edema Bleomycin 20.7517118201
MESH:D004487 Edema Furosemide 20.7511834646
MESH:D004487 Edema imatinib 20.7519703484
MESH:D004487 Edema Plant Extracts 20.7512787963
MESH:D004487 Edema resveratrol 20.758985016
MESH:D004487 Edema Tetrachlorodibenzodioxin 20.7512711302 11000095
MESH:D004487 Edema Tetradecanoylphorbol Acetate 20.758273558 9599246 11698051 7812673 15177302 16716910 8113982
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 9.0016714409 15322242 18230668
MESH:D004489 Edema, Cardiac Tretinoin 9.0018230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental 15-deoxy-delta(12,14)-prostaglandin J2 10.8816844232
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 10.8815138306
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 10.8817872969
MESH:D004701 Endocrine Gland Neoplasms decitabine 4.2319294695
MESH:D016889 Endometrial Neoplasms Doxorubicin 12.6217359293
MESH:D016889 Endometrial Neoplasms Estradiol 12.6211473722 18566989 19148513
MESH:D016889 Endometrial Neoplasms Folic Acid 12.6217301261
MESH:D016889 Endometrial Neoplasms Tretinoin 12.6216569247
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.259294722 10568697
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 11.1118037988
MESH:D004719 Endomyocardial Fibrosis Plant Extracts 11.1115268973
MESH:D020345 Enterocolitis, Necrotizing resveratrol 3.9917923197
MESH:D004827 Epilepsy Plant Extracts 3.2119439326 19700373
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7.6620426865
MESH:D004938 Esophageal Neoplasms Cisplatin 7.6617638652 16481741 16785472 15464296 15173087
MESH:D004938 Esophageal Neoplasms Fluorouracil 7.6616785472 16337965 16481741 17638652 15173087
MESH:D004938 Esophageal Neoplasms Paclitaxel 7.6616481741
MESH:D017889 Exfoliation Syndrome Folic Acid 4.6216504073
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 6.5211564622
MESH:D005124 Eye Abnormalities Tretinoin 6.529664655 16938888
MESH:D005221 Fatigue vorinostat 4.7220479100
MESH:D005234 Fatty Liver arsenite 16.4018296743
MESH:D005234 Fatty Liver Carbon Tetrachloride 16.4061145 16045604 12631006 15959796 19224547 16239168 12795759 17595544
MESH:D005234 Fatty Liver Curcumin 16.4019297423
MESH:D005234 Fatty Liver Cyclosporine 16.4019224547
MESH:D005234 Fatty Liver Plant Extracts 16.4015975614
MESH:D005264 Femoral Fractures zoledronic acid 4.9516234978
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 2.6111858732
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 9.0919069698
MESH:D018222 Fibromatosis, Aggressive imatinib 9.0917453242
MESH:D005355 Fibrosis arsenite 23.6418296743
MESH:D005355 Fibrosis Carbon Tetrachloride 23.6418705752
MESH:D005355 Fibrosis Curcumin 23.6418705752
MESH:D005355 Fibrosis Cyclosporine 23.6412168785 12639820
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 23.6420067830
MESH:D005355 Fibrosis Tretinoin 23.6417994277
MESH:D005756 Gastritis Acetaminophen 8.3316983495
MESH:D005756 Gastritis Folic Acid 8.3317171786
MESH:D005770 Gastrointestinal Neoplasms Curcumin 3.8418462866
MESH:D005833 Genital Neoplasms, Female sodium arsenite 3.8116452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.348708960
MESH:D005901 Glaucoma Folic Acid 4.2616504073
MESH:D005909 Glioblastoma Curcumin 11.8117596214
MESH:D005909 Glioblastoma Doxorubicin 11.8117150277
MESH:D005909 Glioblastoma Fenretinide 11.8116187019
MESH:D005909 Glioblastoma Tretinoin 11.8117312396
MESH:D005910 Glioma Fluorouracil 2.4416145905
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 3.7010696789
MESH:D006261 Headache Nitric Oxide 4.2911284996 11554966
MESH:D006258 Head and Neck Neoplasms Cisplatin 26.4315464296 15102660
MESH:D006258 Head and Neck Neoplasms Curcumin 26.4318462866 18829502
MESH:D006258 Head and Neck Neoplasms decitabine 26.4319215824
MESH:D006258 Head and Neck Neoplasms Doxorubicin 26.4315692506
MESH:D006258 Head and Neck Neoplasms Fluorouracil 26.4315162350 18337622 15102660
MESH:D006258 Head and Neck Neoplasms Sirolimus 26.4319435901
MESH:D006258 Head and Neck Neoplasms Tretinoin 26.4316096774
MESH:D034381 Hearing Loss Cisplatin 7.7419898482
MESH:D034381 Hearing Loss Furosemide 7.7417868369
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.2716084493
MESH:D006319 Hearing Loss, Sensorineural Cisplatin 3.6715464296
MESH:D006330 Heart Defects, Congenital Folic Acid 11.5017286298 16524890
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 11.5011294989 10048152
MESH:D006330 Heart Defects, Congenital Tretinoin 11.509664655 14991402
MESH:D006330 Heart Defects, Congenital Vitamin E 11.5016080930
MESH:D006331 Heart Diseases Doxorubicin 5.8818006777 16244371 16244372 17888722 16495754 16144979 16707910 12587719 18674790 17875725 16330681 14766674 16879835
MESH:D006331 Heart Diseases Mitoxantrone 5.8816019553
MESH:D006333 Heart Failure Doxorubicin 11.9717481944
MESH:D006333 Heart Failure Furosemide 11.9716011733 12660669 16845234
MESH:D006333 Heart Failure Plant Extracts 11.9718097624
MESH:D006333 Heart Failure Selenium 11.9717162251
MESH:D006394 Hemangiosarcoma Doxorubicin 3.1215692506
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 3.5515720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.5411000095
MESH:D006505 Hepatitis Carbon Tetrachloride 2.7719900420 19110552
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 2.0616120746 15340226 12621046
MESH:D015417 Hereditary Sensory and Motor Neuropathy Curcumin 4.1817701891
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.3116863852 16490937
MESH:D006558 Herpes Genitalis Estradiol 4.1415709030
MESH:D006561 Herpes Simplex Etoposide 11.5710809021
MESH:D006561 Herpes Simplex Plant Extracts 11.5710715843
MESH:D006561 Herpes Simplex resveratrol 11.5716876885
MESH:D015658 HIV Infections marker/mechanism 12878215
MESH:D015658 HIV Infections Plant Extracts 3.1612878215
MESH:D006679 HIV Seropositivity Folic Acid 4.6217209195
MESH:D006689 Hodgkin Disease Bleomycin 18.9615147373 18501091 17606976
MESH:D006689 Hodgkin Disease Cisplatin 18.9616200630 16170182
MESH:D006689 Hodgkin Disease Doxorubicin 18.9615147373 18501091 17606976
MESH:D006689 Hodgkin Disease Etoposide 18.9618180244 15147373 17606976 16200630 16135485
MESH:D006689 Hodgkin Disease sodium arsenite 18.9612676792
MESH:D006689 Hodgkin Disease Vinblastine 18.9618501091 18180244
MESH:D019584 Hot Flashes Estradiol 12.0517088409
MESH:D019584 Hot Flashes Plant Extracts 12.0514716179 16566672 17454163
MESH:D019584 Hot Flashes Vitamin E 12.0514716179
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.1618606429 15340226 16959395 16354765 8697196
MESH:D006930 Hyperalgesia Acetaminophen 8.9816870215
MESH:D006930 Hyperalgesia Tretinoin 8.9816870215
MESH:D006930 Hyperalgesia zoledronic acid 8.9816769263
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 3.6616899240
MESH:D006934 Hypercalcemia bortezomib 13.7918089816
MESH:D006934 Hypercalcemia Furosemide 13.7917652376
MESH:D006934 Hypercalcemia zoledronic acid 13.7918089816 19622757
MESH:D053565 Hypercalciuria Furosemide 4.7817652376
MESH:D006937 Hypercholesterolemia Curcumin 6.7618704882
MESH:D006937 Hypercholesterolemia resveratrol 6.7617188708
MESH:D006940 Hyperemia Nitric Oxide 4.7411156591
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 3.7116778211
MESH:D020138 Hyperhomocysteinemia Folic Acid 7.2316865747 16433478 16395265 16755160 16397167
MESH:D020138 Hyperhomocysteinemia Plant Extracts 7.2316484555
MESH:D006949 Hyperlipidemias Plant Extracts 6.9215268973 15975614
MESH:D006949 Hyperlipidemias resveratrol 6.9216873680
MESH:D006962 Hyperparathyroidism, Secondary Furosemide 4.9815086907
MESH:D006973 Hypertension Cyclosporine 3.5110903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 3.5118850075 18670907
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.2315338365
MESH:D046110 Hypertension, Pregnancy-Induced Furosemide 4.4316612254
MESH:D006976 Hypertension, Pulmonary Nitric Oxide 3.7515838368
MESH:D006984 Hypertrophy Sirolimus 4.4319211884
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 3.5217488730
MESH:D006996 Hypocalcemia zoledronic acid 5.3012669777
MESH:D020514 Hypokalemic Periodic Paralysis Potassium 4.9919822448
MESH:C537153 Hypomagnesemia primary Furosemide 4.7811041285
MESH:D007019 Hypoproteinemia Furosemide 4.9816096441
MESH:D007022 Hypotension Furosemide 3.8211041285
MESH:D007024 Hypotension, Orthostatic Furosemide 4.5315811171
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 3.7917600658
MESH:D007248 Infertility, Male decitabine 4.7917581917
MESH:D007248 Infertility, Male sodium arsenite 4.7912646999 15346721
MESH:D007249 Inflammation Bleomycin 15.9617118201
MESH:D007249 Inflammation Curcumin 15.9616956363 18403477 17151092
MESH:D007249 Inflammation Flavonoids 15.9617296493
MESH:D007249 Inflammation Plant Extracts 15.9616366677 12787963 19332304 15997105
MESH:D007249 Inflammation resveratrol 15.9616366677
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 15.9612878042 12200463
MESH:D007249 Inflammation Tetradecanoylphorbol Acetate 15.967562506 8273558 7812673 15177302 11698051
MESH:D015212 Inflammatory Bowel Diseases Curcumin 2.7718596194 18200517
MESH:D007251 Influenza, Human resveratrol 13.5216624496
MESH:D007251 Influenza, Human Selenium 13.5216624496
MESH:D007251 Influenza, Human Vitamin E 13.5216624496
MESH:D007333 Insulin Resistance Estradiol 5.3216393666 16627594
MESH:D007333 Insulin Resistance Sodium Selenite 5.3214714311
MESH:D007410 Intestinal Diseases Nitric Oxide 7.2911574821 11713966 10210152
MESH:D007410 Intestinal Diseases Tretinoin 7.2917994277
MESH:D007414 Intestinal Neoplasms caffeic acid phenethyl ester 12.0710783313
MESH:D007414 Intestinal Neoplasms Curcumin 12.0710783313
MESH:D007414 Intestinal Neoplasms Plant Extracts 12.0712584176 12351151 12628509
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 7.2916580747
MESH:D007569 Jaw Abnormalities Tretinoin 7.2917551590 15992940
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 3.5515604871
MESH:D007673 Kidney Cortex Necrosis Cisplatin 4.2515464296
MESH:D007674 Kidney Diseases Acetaminophen 40.2015629191 12587719
MESH:D007674 Kidney Diseases Acrolein 40.2012488133
MESH:D007674 Kidney Diseases Cadmium 40.2016962696 16226777 16322080
MESH:D007674 Kidney Diseases Cadmium Chloride 40.2016962696
MESH:D007674 Kidney Diseases caffeic acid phenethyl ester 40.2015369732
MESH:D007674 Kidney Diseases Cisplatin 40.2018289764 15190930 19839026 12231392 12649298
MESH:D007674 Kidney Diseases Cyclosporine 40.208314463 18776723 10903974
MESH:D007674 Kidney Diseases Doxorubicin 40.2015369732 16775033 15699352
MESH:D007674 Kidney Diseases Estradiol 40.2015618244
MESH:D007674 Kidney Diseases Furosemide 40.2011041285
MESH:D007674 Kidney Diseases sodium arsenite 40.2020008137
MESH:D007674 Kidney Diseases Vitamin E 40.2012488133
MESH:D007676 Kidney Failure, Chronic Doxorubicin 7.3416707910
MESH:D007676 Kidney Failure, Chronic Selenium 7.3416518626
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 11.7716705839
MESH:D007680 Kidney Neoplasms Cyclosporine 11.7712371664
MESH:D007680 Kidney Neoplasms Estradiol 11.7715610895
MESH:D007680 Kidney Neoplasms Fluorouracil 11.7716985049
MESH:D007683 Kidney Tubular Necrosis, Acute Cisplatin 3.9111231351
MESH:D007889 Leiomyoma Curcumin 3.7518555241
MESH:D007896 Leishmaniasis Nitric Oxide 3.9117218153
MESH:D007938 Leukemia marker/mechanism 12970779
MESH:D007938 Leukemia 1L-6-hydroxymethyl-chiro-inositol 2(R)-2-O-methyl-3-O-octadecylcarbonate 17.8112970779
MESH:D007938 Leukemia 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 17.8112970779
MESH:D007938 Leukemia Curcumin 17.8118462866
MESH:D007938 Leukemia decitabine 17.8119235587 18980019
MESH:D007938 Leukemia SN50 peptide 17.8112970779
MESH:D007938 Leukemia Tretinoin 17.8117143497
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 4.2716085563
MESH:D015451 Leukemia, Lymphocytic, Chronic, B-Cell bendamustine 5.9018980985
MESH:D015451 Leukemia, Lymphocytic, Chronic, B-Cell Mitoxantrone 5.9018172266
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell bortezomib 11.9818089816
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Curcumin 11.9816106398
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell zoledronic acid 11.9818089816
MESH:D007948 Leukemia, Monocytic, Acute anthra(1,9-cd)pyrazol-6(2H)-one 4.5016972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive imatinib 7.1617301526 19208803 15748426 15107311
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive tetraarsenic tetrasulfide 7.1619208803
MESH:D007951 Leukemia, Myeloid decitabine 11.6018454857 17236224 19117987
MESH:D007951 Leukemia, Myeloid imatinib 11.6017236224
MESH:D007951 Leukemia, Myeloid Tretinoin 11.6019285840 16482212 16932348
MESH:D015470 Leukemia, Myeloid, Acute bortezomib 4.8220471514
MESH:D015470 Leukemia, Myeloid, Acute decitabine 4.8218460780 19387464 17679729 18206229 19010910 18704418
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 4.8216294345 19850784 17596541
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 4.5718055864
MESH:D015473 Leukemia, Promyelocytic, Acute caffeic acid phenethyl ester 13.0816766008
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 13.0816087638
MESH:D015473 Leukemia, Promyelocytic, Acute Thiophenes 13.0816140954 16140955
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 13.0819029980 17368321 17506722 19035177 12679006 16788101 16823087 19075265 19225113 16766008 17294898 9834237 16891316 17107899 17649720 16331271 17361223 19642359 17301526 15748426 16935935 17712046 17217047 17339181 16140955
MESH:D015458 Leukemia, T-Cell Curcumin 3.9316106398
MESH:D007972 Leukoplakia, Oral Fenretinide 5.1516707609
MESH:D017880 Limb Deformities, Congenital Tretinoin 2.649224671
MESH:D008080 Liposarcoma Paclitaxel 4.0017353645
MESH:D008103 Liver Cirrhosis arsenite 7.9218296743
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 7.9216239168 16943688 17334410 11408273 17157831 11903743 21278145 16221502 17174718
MESH:D008103 Liver Cirrhosis Plant Extracts 7.9217157831
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 13.9218412020 16033810 18418968 17900296 13678700 18395095 17714472 15052691 17557913 20821823 18251166 15362042 18395914 17922224 15876570 15057751 18429990 15893842 17640975 17944888 12445421 18277467 12898905 12632512 16027843 14748882 18156304 18187930 12546737 16097048 18376398 18339082 18279442 12586293 18205269 15959796 15996030 16638106 12667390 15931870 12958196 11481614 17525996 17565644 10355542 12649538 17721639 15123356 15730626 15650968 16015684 16136751 12666154 17631135 17823541 18317297 14512876 12741479 15370692 16116963 16248980 14724832 14716496 16192424 18210741 14716833 18006644 18481824 14620537 18263696 15925388 17481882 17698563 18472094 12389079 18420326 17761835 17869086 15818738 18705752 18054572 17976157 17805973 12609069 15338365 18472332 12632514 17766677 17708605 16011737 15673190 18166357 12445418
MESH:D008106 Liver Cirrhosis, Experimental Curcumin 13.9218705752 18006644 17355460
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 13.9216595196 16439617
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 13.9214716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental imatinib 13.9216596278
MESH:D008106 Liver Cirrhosis, Experimental Plant Extracts 13.9215479170
MESH:D008106 Liver Cirrhosis, Experimental Sirolimus 13.9217050028
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 13.9212878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 13.9216248980 18397230
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 13.9216169303
MESH:D008107 Liver Diseases Acetaminophen 11.4616610002 19784758 11587558 12969438 12587719 16611625 19460945 19014921
MESH:D008107 Liver Diseases Carbon Tetrachloride 11.4617285989 15830285 16964402 16246199 15720792
MESH:D008107 Liver Diseases Curcumin 11.4616956363
MESH:D008107 Liver Diseases Folic Acid 11.4616877991
MESH:D008107 Liver Diseases Hemin 11.4617173083
MESH:D008107 Liver Diseases Plant Extracts 11.4617034775
MESH:D017093 Liver Failure Carbon Tetrachloride 3.3115123358
MESH:D017114 Liver Failure, Acute Acetaminophen 6.8316871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 6.8316899240 14706259
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 18.1919294768
MESH:D008113 Liver Neoplasms Fluorouracil 18.1915113037 17045692 16603448 18383874
MESH:D008113 Liver Neoplasms Mitomycin 18.1915113037
MESH:D008113 Liver Neoplasms Plant Extracts 18.1919168119
MESH:D008113 Liver Neoplasms resveratrol 18.1920405173 19073162 19812893 19321006
MESH:D008113 Liver Neoplasms sodium arsenite 18.1915276417 16712894
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 18.1916984957
MESH:D008113 Liver Neoplasms zerumbone 18.1920452335
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 9.1515583823 12014681
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 9.1516842330 17085340
MESH:D008114 Liver Neoplasms, Experimental kojic acid 9.1518544905
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 9.1512151625
MESH:D008171 Lung Diseases Acrolein 8.7311504702
MESH:D008171 Lung Diseases sodium arsenite 8.7319095001
MESH:D008171 Lung Diseases Vitamin E 8.7316863852
MESH:D055370 Lung Injury Nitric Oxide 3.8911395602
MESH:D008175 Lung Neoplasms arsenite 15.8216809336
MESH:D008175 Lung Neoplasms Bleomycin 15.826189445
MESH:D008175 Lung Neoplasms Cisplatin 15.8211798837 17225452 6189445
MESH:D008175 Lung Neoplasms Curcumin 15.8218462866 19359593 16243823
MESH:D008175 Lung Neoplasms Doxorubicin 15.826189445 17418594
MESH:D008175 Lung Neoplasms Fluorouracil 15.8215246190
MESH:D008175 Lung Neoplasms Plant Extracts 15.8220869020
MESH:D008175 Lung Neoplasms sodium arsenite 15.8217306315 19931552 17077188 15276417 16712894
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 15.8219555203 11884234
MESH:D008175 Lung Neoplasms Tetradecanoylphorbol Acetate 15.8211807781
MESH:D008175 Lung Neoplasms Vitamin E 15.8211062179
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 3.9215086387
MESH:D008180 Lupus Erythematosus, Systemic Folic Acid 3.0117718048
MESH:D008223 Lymphoma bortezomib 24.9616098063
MESH:D008223 Lymphoma Chlorambucil 24.9610745627
MESH:D008223 Lymphoma Curcumin 24.9618462866
MESH:D008223 Lymphoma decitabine 24.9619470736
MESH:D008223 Lymphoma Doxorubicin 24.9616098063
MESH:D008223 Lymphoma Etoposide 24.9612854902 12556972
MESH:D008223 Lymphoma Nitric Oxide 24.9616166326
MESH:D016393 Lymphoma, B-Cell bortezomib 12.6116675587
MESH:D016393 Lymphoma, B-Cell resveratrol 12.6117088997
MESH:D016393 Lymphoma, B-Cell Sodium Selenite 12.6114737004
MESH:D020522 Lymphoma, Mantle-Cell bendamustine 5.4318980985
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 10.3617654614
MESH:D008228 Lymphoma, Non-Hodgkin Paclitaxel 10.3614749477
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 10.3614749477
MESH:D016399 Lymphoma, T-Cell 3-(4-methylphenylsulfonyl)-2-propenenitrile 14.7016173963
MESH:D016399 Lymphoma, T-Cell Curcumin 14.7016173963
MESH:D016399 Lymphoma, T-Cell Doxorubicin 14.7015621674
MESH:D016410 Lymphoma, T-Cell, Cutaneous vorinostat 4.8320479100
MESH:D015674 Mammary Neoplasms, Animal resveratrol 3.3815688416
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 18.9915458769
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 18.9917203775 11408345 16891317 11807958
MESH:D008325 Mammary Neoplasms, Experimental Fenretinide 18.9910697514
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 18.998985016 11606380
MESH:D008325 Mammary Neoplasms, Experimental Selenium 18.9915318939
MESH:D008325 Mammary Neoplasms, Experimental Tetradecanoylphorbol Acetate 18.998985016
MESH:D008325 Mammary Neoplasms, Experimental zoledronic acid 18.9917312309
MESH:D020149 Manganese Poisoning Estradiol 3.5919453300
MESH:D019767 Maxillofacial Abnormalities Folic Acid 4.8216832597
MESH:D008527 Medulloblastoma bortezomib 5.4019213072
MESH:D008527 Medulloblastoma Tretinoin 5.4017453147
MESH:D008545 Melanoma Bleomycin 27.7615577320
MESH:D008545 Melanoma Carboplatin 27.7611712820 12040289 16225601 16342250
MESH:D008545 Melanoma Cisplatin 27.7618505091 11135225 17023156 18176117 12374674 12883367 16248763 18332650 16432458 12393984 16809738 15577323 17761969
MESH:D008545 Melanoma Curcumin 27.7617885582 18462866
MESH:D008545 Melanoma decitabine 27.7616505122 17785578
MESH:D008545 Melanoma Doxorubicin 27.7616827129
MESH:D008545 Melanoma Fenretinide 27.7616270382
MESH:D008545 Melanoma Paclitaxel 27.7616342250 12025231 12040289
MESH:D008545 Melanoma resveratrol 27.7617992120
MESH:D008545 Melanoma Sirolimus 27.7619282848
MESH:D008545 Melanoma sodium arsenite 27.7616487513 19082730
MESH:D008545 Melanoma Tretinoin 27.7616752155
MESH:D008545 Melanoma Vinblastine 27.7612374674 18505091 15577320 16432458 18176117 15577323 17761969 16809738 16248763 18332650
MESH:D018328 Melanoma, Amelanotic Cisplatin 3.9015990972
MESH:D008546 Melanoma, Experimental Acetaminophen 8.1519513568
MESH:D008546 Melanoma, Experimental Acrolein 8.1510803710
MESH:D008569 Memory Disorders Curcumin 3.3317263510
MESH:D008591 Meningomyelocele Tretinoin 3.5716940565
MESH:D008654 Mesothelioma Cisplatin 10.8417638057
MESH:D008654 Mesothelioma Doxorubicin 10.8417638057
MESH:D008654 Mesothelioma Selenium 10.8415107826
MESH:D008654 Mesothelioma zoledronic acid 10.8416675582
MESH:D008659 Metabolic Diseases resveratrol 3.5817112576
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 3.9016801185
MESH:D053842 Microsatellite Instability Methylnitronitrosoguanidine 5.0117671175
MESH:D008881 Migraine Disorders Nitric Oxide 3.6211701602
MESH:D020326 Migraine without Aura Nitric Oxide 4.2814659530 11304026
MESH:D028361 Mitochondrial Diseases Doxorubicin 3.7015792986
MESH:D009062 Mouth Neoplasms Fenretinide 10.5816274795
MESH:D009062 Mouth Neoplasms Fluorouracil 10.5816757204 18986760
MESH:D009062 Mouth Neoplasms Sirolimus 10.5819435901
MESH:D052016 Mucositis Doxorubicin 9.5217415656
MESH:D052016 Mucositis irinotecan 9.5217159606
MESH:D009101 Multiple Myeloma bortezomib 23.8419112817 19372569 19112201
MESH:D009101 Multiple Myeloma Curcumin 23.8419372569
MESH:D009101 Multiple Myeloma decitabine 23.8418172295
MESH:D009101 Multiple Myeloma lonafarnib 23.8416996129
MESH:D009101 Multiple Myeloma Paclitaxel 23.8414749477
MESH:D009101 Multiple Myeloma resveratrol 23.8417935668 17164350 17049120 14749477 16490592 16267019
MESH:D009101 Multiple Myeloma zoledronic acid 23.8418089719 19621390 16996129
MESH:D009134 Muscular Atrophy, Spinal Curcumin 9.5217962980
MESH:D009134 Muscular Atrophy, Spinal resveratrol 9.5217962980
MESH:D009190 Myelodysplastic Syndromes decitabine 5.5418608210 19157545 19010910 16882708
MESH:D009190 Myelodysplastic Syndromes Tretinoin 5.5417596541
MESH:D009203 Myocardial Infarction Doxorubicin 4.4919429709 15857846
MESH:D009203 Myocardial Infarction resveratrol 4.4916525036 17125593 17188708 16456233 16317513 17015251
MESH:D017202 Myocardial Ischemia resveratrol 6.6017125593 17015251
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 6.6012213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 2.5816810080
MESH:D009205 Myocarditis resveratrol 3.8917322642
MESH:D009325 Nausea vorinostat 4.6420479100
MESH:D009336 Necrosis 2,4-dinitrotoluene 2.9918551238
MESH:D009361 Neoplasm Invasiveness Curcumin 3.5418495463
MESH:D009362 Neoplasm Metastasis bendamustine 16.5917667603
MESH:D009362 Neoplasm Metastasis Doxorubicin 16.5918259882
MESH:D009362 Neoplasm Metastasis imatinib 16.5915867366
MESH:D009362 Neoplasm Metastasis irinotecan 16.5918259882
MESH:D009362 Neoplasm Metastasis Paclitaxel 16.5915867366
MESH:D009362 Neoplasm Metastasis zoledronic acid 16.5919139120 17312309 15867366
MESH:D009369 Neoplasms Acrolein 22.4717329238
MESH:D009369 Neoplasms Carboplatin 22.4717925555 18854779
MESH:D009369 Neoplasms Cisplatin 22.4716773208
MESH:D009369 Neoplasms decitabine 22.4717925555 19116145 19470736
MESH:D009369 Neoplasms Fenretinide 22.4715958647 17353921
MESH:D009369 Neoplasms Fluorouracil 22.4716928823 18600527 18239605
MESH:D009369 Neoplasms Mitoxantrone 22.4716640825
MESH:D009369 Neoplasms sodium arsenite 22.4711559025
MESH:D009369 Neoplasms Tretinoin 22.4716594593 16946489
MESH:D009374 Neoplasms, Experimental resveratrol 6.428985016
MESH:D009374 Neoplasms, Experimental sodium arsenite 6.4220056578
MESH:D009376 Neoplasms, Hormone-Dependent Curcumin 8.4412497104
MESH:D009376 Neoplasms, Hormone-Dependent imatinib 8.4417614352
MESH:D009389 Neovascularization, Pathologic arsenite 7.2715738583
MESH:D009389 Neovascularization, Pathologic Estradiol 7.2717289903
MESH:D009393 Nephritis Acrolein 5.4012653641
MESH:D009395 Nephritis, Interstitial Cisplatin 3.6115464296
MESH:D009397 Nephrocalcinosis Furosemide 4.9815086907
MESH:D009401 Nephrosis Doxorubicin 3.9116899518 16636307
MESH:D009402 Nephrosis, Lipoid Cyclosporine 3.5517954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 6.7819348381 18481113
MESH:D009404 Nephrotic Syndrome Doxorubicin 6.7815640375 16889571
MESH:D009421 Nervous System Malformations Estradiol 11.5411399458 16427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 11.5414600291
MESH:D009421 Nervous System Malformations Tretinoin 11.549125849
MESH:D009423 Nervous System Neoplasms Curcumin 4.7418462866
MESH:D009436 Neural Tube Defects Folic Acid 8.5917438019
MESH:D009436 Neural Tube Defects sodium arsenite 8.5912854658
MESH:D009436 Neural Tube Defects Tretinoin 8.599142499
MESH:D019954 Neurobehavioral Manifestations Plant Extracts 4.3317168769
MESH:D009447 Neuroblastoma Cisplatin 11.858761367
MESH:D009447 Neuroblastoma Doxorubicin 11.8515555623
MESH:D009447 Neuroblastoma irinotecan 11.858761367
MESH:D009447 Neuroblastoma Topotecan 11.8515176712
MESH:D019636 Neurodegenerative Diseases Acetaminophen 9.9518514411
MESH:D019636 Neurodegenerative Diseases Acrolein 9.9511342003
MESH:D019636 Neurodegenerative Diseases resveratrol 9.9517652729
MESH:D017599 Neuroectodermal Tumors Carboplatin 14.2012837982
MESH:D017599 Neuroectodermal Tumors Cisplatin 14.208761367
MESH:D017599 Neuroectodermal Tumors irinotecan 14.208761367
MESH:D020078 Neurogenic Inflammation resveratrol 3.5817929310
MESH:D009472 Neuronal Ceroid-Lipofuscinoses Fenretinide 4.8016303764
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 2.8016436463
MESH:D009503 Neutropenia Folic Acid 7.1316322990
MESH:D009503 Neutropenia Vinblastine 7.1317378895
MESH:D053206 Nocturnal Enuresis Furosemide 4.9817945291
MESH:D009765 Obesity Curcumin 4.0319297423
MESH:D009765 Obesity Plant Extracts 4.0320132043 19056576
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 2.6616049721 12819281
MESH:D010014 Osteolysis imatinib 15.4315867366
MESH:D010014 Osteolysis Paclitaxel 15.4315867366
MESH:D010014 Osteolysis zoledronic acid 15.4315867366
MESH:D010024 Osteoporosis Curcumin 5.6218719352
MESH:D010024 Osteoporosis zoledronic acid 5.6217882678
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 3.4417513867
MESH:D012516 Osteosarcoma Doxorubicin 3.3815930896
MESH:D010051 Ovarian Neoplasms 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 27.3216211241
MESH:D010051 Ovarian Neoplasms Cisplatin 27.3217225452 15464296 6897625 19769630
MESH:D010051 Ovarian Neoplasms Curcumin 27.3218462866 19020741
MESH:D010051 Ovarian Neoplasms decitabine 27.3219331143 19259094
MESH:D010051 Ovarian Neoplasms Estradiol 27.3219401270
MESH:D010051 Ovarian Neoplasms Fenretinide 27.3216133793
MESH:D010051 Ovarian Neoplasms Luteolin 27.3219005980
MESH:D010051 Ovarian Neoplasms Paclitaxel 27.3211161223
MESH:D010051 Ovarian Neoplasms sodium arsenite 27.3215276417 17306315
MESH:D010051 Ovarian Neoplasms Tretinoin 27.3216936753
MESH:D010146 Pain Acetaminophen 7.1616870215
MESH:D010146 Pain Tretinoin 7.1616870215
MESH:D010146 Pain zoledronic acid 7.1616475674
MESH:D010190 Pancreatic Neoplasms Cisplatin 33.2819003803
MESH:D010190 Pancreatic Neoplasms Curcumin 33.2817440100 19196508 19401701
MESH:D010190 Pancreatic Neoplasms decitabine 33.2819294695
MESH:D010190 Pancreatic Neoplasms dehydroxymethylepoxyquinomicin 33.2816211219
MESH:D010190 Pancreatic Neoplasms Etoposide 33.2819003803
MESH:D010190 Pancreatic Neoplasms Fenretinide 33.2815580305
MESH:D010190 Pancreatic Neoplasms Fluorouracil 33.2816929163 16500647 19003803 15113037
MESH:D010190 Pancreatic Neoplasms gemcitabine 33.2811504793 18383843 17440100 18992248 16929163
MESH:D010190 Pancreatic Neoplasms Mitomycin 33.2815113037
MESH:D010190 Pancreatic Neoplasms Tetradecanoylphorbol Acetate 33.2815976015
MESH:D010190 Pancreatic Neoplasms Tretinoin 33.2815976015
MESH:D010212 Papilloma Plant Extracts 6.9615173996 16517061
MESH:D010212 Papilloma Tetradecanoylphorbol Acetate 6.9618404319 12065085 8330346 18922899
MESH:D010300 Parkinson Disease Acrolein 4.7317690948
MESH:D010300 Parkinson Disease Sirolimus 4.7319682553
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.3612520081
MESH:D010523 Peripheral Nervous System Diseases Cisplatin 3.4815464296
MESH:D016491 Peripheral Vascular Diseases Cadmium 4.5115687053
MESH:D010787 Photosensitivity Disorders Acrolein 4.8511550810
MESH:D003557 Phyllodes Tumor Doxorubicin 4.2717983394
MESH:D010954 Plasmacytoma Selenium 4.0015087411
MESH:D010997 Pleural Neoplasms Cisplatin 10.9917638057
MESH:D010997 Pleural Neoplasms Doxorubicin 10.9917638057
MESH:D011014 Pneumonia Bleomycin 4.5417071938 16317386 18024389
MESH:D011015 Pneumonia, Aspiration Nitric Oxide 4.4618573544
MESH:D011141 Polyuria Furosemide 4.7817945291
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 2.7218163543
MESH:D011230 Precancerous Conditions Cyclosporine 2.4712371664
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma imatinib 7.0012476293
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Thioguanine 7.0021297632
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 6.7216679765
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 6.7211896295 11222880 11118676 11399792
MESH:D055728 Primary Myelofibrosis decitabine 3.8717616702
MESH:D011470 Prostatic Hyperplasia Calcitriol 3.9115572423
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.0920887781
MESH:D011471 Prostatic Neoplasms Cadmium 8.1617075824
MESH:D011471 Prostatic Neoplasms Calcitriol 8.1612479363 16289102 18247401 16644109 15754350
MESH:D011471 Prostatic Neoplasms Curcumin 8.1610851300 12497104 18769126 11398177 18226269 18156803 15129424
MESH:D011471 Prostatic Neoplasms Doxorubicin 8.1616729912 15897917 18437689 16888761 16868541 15749863
MESH:D011471 Prostatic Neoplasms Estradiol 8.1616740699
MESH:D011471 Prostatic Neoplasms Etoposide 8.1617172428
MESH:D011471 Prostatic Neoplasms Fenretinide 8.1617024972
MESH:D011471 Prostatic Neoplasms Fluorouracil 8.1618626508 19082440
MESH:D011471 Prostatic Neoplasms methylselenic acid 8.1616205645
MESH:D011471 Prostatic Neoplasms Paclitaxel 8.1616356831 17172428 17136230 16729912
MESH:D011471 Prostatic Neoplasms Plant Extracts 8.1617804756 14666653
MESH:D011471 Prostatic Neoplasms resveratrol 8.1616731767 17636462 15767336 17804756 17718901 17675339
MESH:D011471 Prostatic Neoplasms sodium arsenite 8.1616039940
MESH:D011471 Prostatic Neoplasms Sodium Selenite 8.1618760546
MESH:D011471 Prostatic Neoplasms Vitamin E 8.1615084515
MESH:D011471 Prostatic Neoplasms vorinostat 8.1617218635
MESH:D011471 Prostatic Neoplasms zoledronic acid 8.1619103299 12438248
MESH:D011507 Proteinuria Tretinoin 2.8016636307
MESH:D011565 Psoriasis Cyclosporine 1.8416882103
MESH:D011625 Pterygium Tretinoin 3.9216723453
MESH:D011654 Pulmonary Edema Bleomycin 4.4415808516
MESH:D011656 Pulmonary Emphysema Curcumin 3.7519168576
MESH:D011658 Pulmonary Fibrosis Bleomycin 3.4614609568 11554783 17177178 15541506 12624602 16115399 17241526 16314464 15322207 18008008 17434272 12574379 18162602 21435439
MESH:D012004 Rectal Neoplasms Fluorouracil 3.2515538739 16160472 18286688 18722050
MESH:D051437 Renal Insufficiency Acrolein 17.5412732208
MESH:D051437 Renal Insufficiency Cisplatin 17.5415464296
MESH:D051437 Renal Insufficiency Doxorubicin 17.5417922066
MESH:D051437 Renal Insufficiency Folic Acid 17.5415728788
MESH:D051436 Renal Insufficiency, Chronic resveratrol 4.6916325855
MESH:D015427 Reperfusion Injury Furosemide 5.3916526316
MESH:D015427 Reperfusion Injury resveratrol 5.3916317513 16314181 17520802 17058453 15827377
MESH:D012128 Respiratory Distress Syndrome, Adult Curcumin 6.8410666014 18379247
MESH:D012128 Respiratory Distress Syndrome, Adult Furosemide 6.8412394941 15912074 16096441
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.0018990726
MESH:D012162 Retinal Degeneration Fenretinide 3.7116303925
MESH:D012175 Retinoblastoma SN50 peptide 5.6212466137
MESH:D012208 Rhabdomyosarcoma decitabine 8.2419155313
MESH:D012208 Rhabdomyosarcoma Tretinoin 8.2416116481 16283617
MESH:D012509 Sarcoma Curcumin 6.9918462866
MESH:D012509 Sarcoma Doxorubicin 6.9917710206 17203757 15625365 18313854 16767912 15675481
MESH:D012512 Sarcoma, Ewing's Cisplatin 17.8914601052
MESH:D012512 Sarcoma, Ewing's Doxorubicin 17.8916326096 14601052
MESH:D012512 Sarcoma, Ewing's Etoposide 17.8914601052
MESH:D012512 Sarcoma, Ewing's zoledronic acid 17.8916121404
MESH:D012514 Sarcoma, Kaposi Doxorubicin 3.9217846226
MESH:D012555 Schistosomiasis mansoni Nitric Oxide 4.619673227
MESH:D012559 Schizophrenia Folic Acid 2.7516641680
MESH:D012640 Seizures 2,4-dinitrotoluene 1.9518551238
MESH:D018805 Sepsis Curcumin 3.3418389075
MESH:D012871 Skin Diseases Folic Acid 4.1218709164
MESH:D012871 Skin Diseases Vitamin E 4.1218709164
MESH:D012878 Skin Neoplasms Doxorubicin 23.1215692506
MESH:D012878 Skin Neoplasms Fenretinide 23.1216467112
MESH:D012878 Skin Neoplasms Plant Extracts 23.1216517061 15173996
MESH:D012878 Skin Neoplasms resveratrol 23.128985016 15837718
MESH:D012878 Skin Neoplasms sodium arsenite 23.1218572023 19524636
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 23.1216192470
MESH:D012878 Skin Neoplasms Tetradecanoylphorbol Acetate 23.128985016 11807781 8330346 12065085 18404319
MESH:D012878 Skin Neoplasms Tretinoin 23.1216467112
MESH:D055752 Small Cell Lung Carcinoma Cisplatin 4.4515464296
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 3.7117203757 16767912 15625365
MESH:D013118 Spinal Cord Diseases Folic Acid 4.6216361298
MESH:D016135 Spinal Dysraphism sodium arsenite 3.0812854658
MESH:D013274 Stomach Neoplasms marker/mechanism 14647439
MESH:D013274 Stomach Neoplasms Cisplatin 11.6817522103 15958060 18396642
MESH:D013274 Stomach Neoplasms decitabine 11.6819037991
MESH:D013274 Stomach Neoplasms Fluorouracil 11.6818396642 15786421 17522103 16424979 18567086 19015929 17172411 16951190 19084572 17498489
MESH:D013274 Stomach Neoplasms Folic Acid 11.6817171786
MESH:D013274 Stomach Neoplasms Furosemide 11.6817052386
MESH:D013274 Stomach Neoplasms imatinib 11.6815786421
MESH:D013274 Stomach Neoplasms irinotecan 11.6815723263
MESH:D013274 Stomach Neoplasms Paclitaxel 11.6818396642 18506536
MESH:D013274 Stomach Neoplasms Tretinoin 11.6817261132
MESH:D013276 Stomach Ulcer Curcumin 10.9816631530 19188055
MESH:D013276 Stomach Ulcer fucoidan 10.9815138204 18209962
MESH:D013276 Stomach Ulcer Nitric Oxide 10.9815138204
MESH:D013276 Stomach Ulcer Plant Extracts 10.9815255614 18193104 17135157 12787963 18237397
MESH:D020521 Stroke Acrolein 10.4416269634
MESH:D020521 Stroke Folic Acid 10.4416517955
MESH:D020521 Stroke Vitamin E 10.4416517955
OMIM:601367 STROKE, ISCHEMIC resveratrol 3.7016321402
MESH:D015173 Supratentorial Neoplasms Carboplatin 4.9412837982
MESH:D024801 Tauopathies Paclitaxel 3.9416930453
MESH:D013705 Temporomandibular Joint Disorders Plant Extracts 4.5917997062
MESH:D013736 Testicular Neoplasms Cisplatin 3.8115464296 17225452
MESH:D013921 Thrombocytopenia vorinostat 4.2020479100
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.0112697716
MESH:D013964 Thyroid Neoplasms Butyrates 15.1517967635
MESH:D013964 Thyroid Neoplasms decitabine 15.1517967635
MESH:D013964 Thyroid Neoplasms Doxorubicin 15.1517909728 16010429
MESH:D013964 Thyroid Neoplasms imatinib 15.1516940797
MESH:D013964 Thyroid Neoplasms Tretinoin 15.1517045167 16026305
MESH:D013978 Tibial Fractures Estradiol 3.8019048282
MESH:D014062 Tongue Neoplasms Fluorouracil 12.1016280240
MESH:D014062 Tongue Neoplasms resveratrol 12.1016227395
MESH:D014062 Tongue Neoplasms Tretinoin 12.1016051514
MESH:D014376 Tuberculosis Tretinoin 2.6216040207
MESH:D014402 Tuberous Sclerosis Sirolimus 4.7321115397 18495876
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 17.2416049721
MESH:D001749 Urinary Bladder Neoplasms Cisplatin 17.2412973940 17225452 15464296
MESH:D001749 Urinary Bladder Neoplasms Curcumin 17.2418593936
MESH:D001749 Urinary Bladder Neoplasms decitabine 17.2417616700 19087683
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 17.2417653716
MESH:D001749 Urinary Bladder Neoplasms Fenretinide 17.2416720286
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 17.2416712894 16452187 17306315 11723127
MESH:D014565 Urogenital Neoplasms Curcumin 4.3918462866
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 3.4410091137
MESH:D014581 Urticaria Acetaminophen 2.1810982225
MESH:D002583 Uterine Cervical Neoplasms Cisplatin 32.6616803524
MESH:D002583 Uterine Cervical Neoplasms Fenretinide 32.6616154183
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 32.6616803524
MESH:D002583 Uterine Cervical Neoplasms indole-3-carbinol 32.6616082211
MESH:D002583 Uterine Cervical Neoplasms resveratrol 32.6617473185
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 32.6611813266
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 32.6616129372
MESH:D014594 Uterine Neoplasms resveratrol 3.3117044934
MESH:D014604 Uveal Neoplasms decitabine 9.8817785578
MESH:D014604 Uveal Neoplasms Tretinoin 9.8816752155
MESH:D014605 Uveitis Cyclosporine 9.121336536
MESH:D014605 Uveitis Sirolimus 9.121336536
MESH:D014625 Vaginal Neoplasms Cisplatin 8.4815577323
MESH:D014625 Vaginal Neoplasms Vinblastine 8.4815577323
MESH:D014652 Vascular Diseases sodium arsenite 3.5517056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 3.7012125929
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 12.3417334414 16364871 17638931 17678736
MESH:D018487 Ventricular Dysfunction, Left Plant Extracts 12.3418097624
MESH:D018487 Ventricular Dysfunction, Left resveratrol 12.3417488730
MESH:D020257 Ventricular Remodeling Plant Extracts 4.4418097624
MESH:D014820 Vitiligo Tretinoin 3.2216761959
MESH:D014839 Vomiting Cisplatin 3.8311897121
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.3615886252
MESH:D015431 Weight Loss Bleomycin 4.7712624602
MESH:D009396 Wilms Tumor Tretinoin 3.2016287080
MESH:D014947 Wounds and Injuries Plant Extracts 3.5220213670 19894650
MESH:D014985 Xerophthalmia Cyclosporine 3.5517120751
Pathway ID Pathway Name
REACT:578 Apoptosis
KEGG:04210 Apoptosis
KEGG:04510 Focal adhesion
KEGG:04621 NOD-like receptor signaling pathway
KEGG:05200 Pathways in cancer
KEGG:05222 Small cell lung cancer
KEGG:05145 Toxoplasmosis
KEGG:04120 Ubiquitin mediated proteolysis
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA25359
    • No data
    No data
    Releated drug ID Related drug Name
    PA448691busulfan
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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