AutismKB 2.0

Annotation Detail for HSD17B2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:HSD17B2 ( EDH17B2,HSD17,SDR9C2 )
Gene Full Name: hydroxysteroid (17-beta) dehydrogenase 2
Band: 16q23.3
Quick LinksEntrez ID:3294; OMIM: 109685; Uniprot ID:DHB2_HUMAN; ENSEMBL ID: ENSG00000086696; HGNC ID: 5211
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa00140Steroid hormone biosynthesis
hsa01100Metabolic pathways
No data
No data
No data
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1901Endometriosis
1944Breast cancer
1841Stomach cancer
2102Polycystic ovary syndrome
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C014024 2,4,5,2',4',5'-hexachlorobiphenyl 2,4,5,2',4',5'-hexachlorobiphenyl results in decreased expression of HSD17B2 mRNAdecreases expression 20005886
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of HSD17B2 mRNAaffects expression 21346803
C035208 2-amino-4,6-dinitrotoluene 2-amino-4,6-dinitrotoluene affects the expression of HSD17B2 mRNAaffects expression 21346803
C022830 2-methoxyestradiol HSD17B2 protein results in decreased susceptibility to 2-methoxyestradioldecreases response to substance 16397246
C022830 2-methoxyestradiol [HSD17B2 protein results in increased metabolism of and results in decreased activity of 2-methoxyestradiol] which results in increased chemical synthesis of 2-methoxyestronedecreases activity|increases chemical synthesis|increases metabolic processing 16397246
C003655 2-methoxyestrone [HSD17B2 protein results in increased metabolism of and results in decreased activity of 2-methoxyestradiol] which results in increased chemical synthesis of 2-methoxyestronedecreases activity|increases chemical synthesis|increases metabolic processing 16397246
D000082 Acetaminophen Acetaminophen affects the expression of HSD17B2 mRNAaffects expression 17562736
D000082 Acetaminophen Acetaminophen results in decreased expression of HSD17B2 mRNAdecreases expression 15120968
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of HSD17B2 proteinaffects expression 20106945
D000643 Ammonium Chloride Ammonium Chloride affects the expression of HSD17B2 mRNAaffects expression 16483693
D015114 Androstenediol HSD17B2 protein affects the metabolism of Androstenediolaffects metabolic processing 16054388
D015114 Androstenediol HSD17B2 protein results in increased chemical synthesis of Androstenediolincreases chemical synthesis 16054388
D000735 Androstenedione HSD17B2 protein results in increased chemical synthesis of Androstenedioneincreases chemical synthesis 16054388
D000965 Antimony Antimony results in decreased expression of HSD17B2 mRNAdecreases expression 17547211
D000966 Antimony Potassium Tartrate Antimony Potassium Tartrate results in decreased expression of HSD17B2 mRNAdecreases expression 17547211
C006632 arsenic trioxide arsenic trioxide results in decreased expression of HSD17B2 mRNAdecreases expression 17547211
D019324 beta-Naphthoflavone [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of HSD17B2 mRNAaffects cotreatment|increases expression 18164116
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of HSD17B2 mRNAincreases expression 20106945
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide affects the expression of HSD17B2 mRNAaffects expression 20382639
C095105 bexarotene bexarotene results in decreased expression of HSD17B2 mRNAdecreases expression 16648578
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in increased expression of HSD17B2 mRNAincreases expression 15003993
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of HSD17B2 mRNAaffects expression 16239168
D016572 Cyclosporine Cyclosporine results in decreased expression of HSD17B2 mRNAdecreases expression 20106945
D003687 Dehydroepiandrosterone HSD17B2 protein affects the metabolism of Dehydroepiandrosteroneaffects metabolic processing 16054388
D003687 Dehydroepiandrosterone HSD17B2 protein results in increased chemical synthesis of Dehydroepiandrosteroneincreases chemical synthesis 16054388
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of HSD17B2 mRNAaffects cotreatment|increases expression 18164116
D004052 Diethylnitrosamine Diethylnitrosamine results in decreased expression of HSD17B2 mRNAdecreases expression 19638242
D002117 Calcitriol Calcitriol results in increased expression of HSD17B2 mRNAincreases expression 16002434
D004128 Dimethylnitrosamine Dimethylnitrosamine results in decreased expression of HSD17B2 mRNAdecreases expression 17547211
D004128 Dimethylnitrosamine Dimethylnitrosamine results in decreased expression of HSD17B2 mRNAdecreases expression 17072980
D011397 Promegestone mithramycin A inhibits the reaction [Promegestone promotes the reaction [SP1 protein binds to HSD17B2 promoter]]affects binding|decreases reaction|increases reaction 16807381
D011397 Promegestone mithramycin A inhibits the reaction [Promegestone promotes the reaction [SP3 protein binds to HSD17B2 promoter]]affects binding|decreases reaction|increases reaction 16807381
D011397 Promegestone Promegestone promotes the reaction [SP1 protein binds to HSD17B2 promoter]affects binding|increases reaction 16807381
D011397 Promegestone Promegestone promotes the reaction [SP3 protein binds to HSD17B2 promoter]affects binding|increases reaction 16807381
D004958 Estradiol Estradiol results in decreased expression of HSD17B2 mRNAdecreases expression 20106945
D004958 Estradiol HSD17B2 protein affects the metabolism of Estradiolaffects metabolic processing 16054388
D004958 Estradiol HSD17B2 protein results in increased chemical synthesis of Estradiolincreases chemical synthesis 16054388
D004958 Estradiol [Progesterone co-treated with Estradiol] results in increased expression of HSD17B2 mRNAaffects cotreatment|increases expression 17404688
D004970 Estrone HSD17B2 protein affects the metabolism of Estroneaffects metabolic processing 16054388
D004970 Estrone HSD17B2 protein results in increased chemical synthesis of Estroneincreases chemical synthesis 16054388
D005472 Fluorouracil Fluorouracil affects the expression of HSD17B2 mRNAaffects expression 16584549
C039281 furan furan results in increased expression of HSD17B2 mRNAincreases expression 15120968
D006581 Hexachlorobenzene Hexachlorobenzene results in decreased expression of HSD17B2 mRNAdecreases expression 15159207
C066851 mithramycin A mithramycin A inhibits the reaction [Promegestone promotes the reaction [SP1 protein binds to HSD17B2 promoter]]affects binding|decreases reaction|increases reaction 16807381
C066851 mithramycin A mithramycin A inhibits the reaction [Promegestone promotes the reaction [SP3 protein binds to HSD17B2 promoter]]affects binding|decreases reaction|increases reaction 16807381
C066851 mithramycin A mithramycin A inhibits the reaction [SP1 protein binds to HSD17B2 promoter]affects binding|decreases reaction 16807381
C066851 mithramycin A mithramycin A inhibits the reaction [SP3 protein binds to HSD17B2 promoter]affects binding|decreases reaction 16807381
C066851 mithramycin A mithramycin A results in decreased expression of HSD17B2 mRNAdecreases expression 16807381
C406082 monomethylarsonous acid monomethylarsonous acid results in decreased expression of HSD17B2 mRNAdecreases expression 20024957
C006253 pirinixic acid pirinixic acid results in decreased expression of HSD17B2 mRNAdecreases expression 18445702
D011374 Progesterone [Progesterone co-treated with Estradiol] results in increased expression of HSD17B2 mRNAaffects cotreatment|increases expression 17404688
D012176 Retinoids HSD17B2 protein affects the metabolism of Retinoidsaffects metabolic processing 17510238
C009250 sevoflurane sevoflurane affects the expression of HSD17B2 mRNAaffects expression 15967596
D013739 Testosterone HSD17B2 protein affects the metabolism of Testosteroneaffects metabolic processing 16054388
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of HSD17B2 mRNAincreases expression 20106945
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of HSD17B2 mRNAaffects binding|increases expression 16214954
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of HSD17B2 mRNAincreases expression 20005886
17949056
18796159
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of HSD17B2 mRNAincreases expression 16054898
D013752 Tetracycline Tetracycline results in increased expression of HSD17B2 mRNAincreases expression 16917069
D014212 Tretinoin Tretinoin results in increased expression of HSD17B2 mRNAincreases expression 16249480
C032910 triadimefon triadimefon results in decreased expression of HSD17B2 mRNAdecreases expression 16730040
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced 2-amino-4,6-dinitrotoluene 7.437525203
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 7.4315322242 11752688 14514962
MESH:D000138 Acidosis Ammonium Chloride 3.1318287403
MESH:D055371 Acute Lung Injury pirinixic acid 2.7218653653
MESH:D000230 Adenocarcinoma arsenic trioxide 12.1911798837 19825857
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 12.1920127859 20464547
MESH:D000230 Adenocarcinoma Dimethylnitrosamine 12.1916033868
MESH:D000230 Adenocarcinoma Estradiol 12.1911473722
MESH:D000230 Adenocarcinoma Fluorouracil 12.1917638652
MESH:D000236 Adenoma Benzo(a)pyrene 13.896695378
MESH:D000236 Adenoma beta-Naphthoflavone 13.8919389873
MESH:D000236 Adenoma Diethylnitrosamine 13.8910737359 6695378
MESH:D000236 Adenoma Dimethylnitrosamine 13.8919555203
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 14.7818056438 17620307 16434500 19052882 17162532 19061943
MESH:D018248 Adenoma, Liver Cell pirinixic acid 14.7816434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 14.7816835633
MESH:D000309 Adrenal Insufficiency Dehydroepiandrosterone 5.3417302879
MESH:D000505 Alopecia Tretinoin 3.2715955085
MESH:D000740 Anemia Fluorouracil 7.4415504547 17963324 16511603
MESH:D000740 Anemia Tetrachlorodibenzodioxin 7.4411748828
MESH:D000799 Angioedema Acetaminophen 3.4010982225
MESH:D000987 Antisocial Personality Disorder Testosterone 5.417506515
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.6519183758
MESH:D001169 Arthritis, Experimental Tretinoin 2.8116412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.1616292516
MESH:D001249 Asthma Tretinoin 2.2116456186
MESH:D001321 Autistic Disorder Acetaminophen 1.4718445737
MESH:D001471 Barrett Esophagus Tretinoin 3.9916935849
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 18.7916206674
MESH:D001778 Blood Coagulation Disorders pirinixic acid 18.7919483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 18.7912125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 18.7916206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.3515340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.4815746008
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 4.9017868700
MESH:D001930 Brain Injuries Progesterone 3.8415380490 15665606 15845082
MESH:D001943 Breast Neoplasms 2-methoxyestradiol 10.3818223236 15219808
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 10.3820146248 17474063
MESH:D001943 Breast Neoplasms bexarotene 10.3816818667 16344269
MESH:D001943 Breast Neoplasms Calcitriol 10.3811237771
MESH:D001943 Breast Neoplasms Diethylnitrosamine 10.3817474063
MESH:D001943 Breast Neoplasms Estradiol 10.3812948864 18497071 17289903 17018787 16675129 17261762 14630087 19861407
MESH:D001943 Breast Neoplasms Fluorouracil 10.3819217205 18357371 15136595 16595493 18608205 16557594 16110121
MESH:D001943 Breast Neoplasms Hexachlorobenzene 10.3812709520 15061365
MESH:D001943 Breast Neoplasms Progesterone 10.3816175315 15562024 17614352
MESH:D001943 Breast Neoplasms Retinoids 10.3817368321 17491551 19340624
MESH:D001943 Breast Neoplasms Testosterone 10.3817261762
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 10.3820435547
MESH:D001943 Breast Neoplasms Tretinoin 10.3816166294 16443354 16873071
MESH:D001991 Bronchitis Antimony 5.698768112
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.1616813970
MESH:D002051 Burkitt Lymphoma arsenic trioxide 3.9311589617
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.0316111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.3616050911 15700767 3786805 15721981 16011737 16227642 16124888 16192424 10355542 18705752 16097048 15673190
MESH:D002276 Carcinoid Tumor Fluorouracil 4.2316051944
MESH:D002277 Carcinoma Dimethylnitrosamine 12.0319555203
MESH:D002277 Carcinoma Fluorouracil 12.0317121937
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 12.0316835633
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.7216168501
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 18.2116705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 18.213084413
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 18.2121507988 12907637 12619106
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 18.2115553829 14691202 11135700 16217749 15073043
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 18.2118788625
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 18.2119335982 16569478 20007298 17138121 3581430 20514400 19107877 16878318 19394651 16328049 19383236 19208518 19822196 17761372 18665156 19539802 17428255 16830150 21159647 18393292 10737359 3084413 16807293 16288022 19418558 20727157 20512989 10672840 20084675 18506893 20935162 17978847 16698587 16502159 18971187 18788625 18785209 18210153 11831363 19052882 16540662 20214788 16779866 17173139 18978308 17055752 18494052 16935385 20432363 19701751 18056438 19171122 19519916 19919837 20524982 16681979 18691550 17162532 20101231
MESH:D006528 Carcinoma, Hepatocellular Estradiol 18.2116924424
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 18.2117971768 17045692 18930000 16332177 17088986 16799960
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 18.211917145
MESH:D002289 Carcinoma, Non-Small-Cell Lung bexarotene 3.0716247446
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.4319014326
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 2.8118695887
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.7412490120
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 12.8120419170
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 12.8111237771
MESH:D002294 Carcinoma, Squamous Cell Dimethylnitrosamine 12.8116033868
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 12.8116757204 17066447 18986760 16280240
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 12.8116096774 16051514
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.1216120746 18670907 18850075
MESH:D002311 Cardiomyopathy, Dilated Antimony 3.7610334427
MESH:D002386 Cataract Acetaminophen 6.3610977129
MESH:D002386 Cataract Tretinoin 6.3617460283
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 17.9220889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 17.9212371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 17.9217174075 7505956 21159647 2727394
MESH:D002471 Cell Transformation, Neoplastic Estradiol 17.9218566989
MESH:D002471 Cell Transformation, Neoplastic monomethylarsonous acid 17.9219716837
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.1616129372
MESH:D002659 Child Development Disorders, Pervasive Androstenedione 6.3921398041
MESH:D002659 Child Development Disorders, Pervasive Testosterone 6.3920678186
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 8.1219052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 8.1216835633
MESH:D002779 Cholestasis Cyclosporine 6.6919486331
MESH:D002779 Cholestasis pirinixic acid 6.6919176532
MESH:D002822 Choriocarcinoma Tretinoin 4.7216461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 8.7812621046 15340226 16354765 8697196 15668235
MESH:D002972 Cleft Palate Tretinoin 8.789407595
MESH:D002972 Cleft Palate triadimefon 8.7816781842
MESH:D003092 Colitis Tretinoin 3.2917035595
MESH:D003110 Colonic Neoplasms Fluorouracil 2.1617287894 16510598 16340194 15001691 17018589 17725105 17172411 17016597 17169374 18772588
MESH:D015179 Colorectal Neoplasms arsenic trioxide 2.4320501625
MESH:D015179 Colorectal Neoplasms Fluorouracil 2.4317454858 17594712 16331619 18448328 18802399 17255274 18383874 18949393 16282729 16391804 20501625 18288408 17401013 17016601 17695437 17094418 18509181 15289873 16524972 14970324 15148649 16303861
MESH:D000013 Congenital Abnormalities 2-amino-4,6-dinitrotoluene 8.3615095906
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 8.3617141729 14669216
MESH:D023903 Coronary Restenosis arsenic trioxide 3.7812609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 4.9710525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 4.9710048152 20055451 15322242
MESH:D019465 Craniofacial Abnormalities Tretinoin 4.979664655 17551590 9125849 16925845 8800419 10589399 14991402 9142499 9224671 9211117
MESH:D019465 Craniofacial Abnormalities triadimefon 4.9715834900 16875885
MESH:D003490 Cyanosis 2,4-dinitrotoluene 3.5918551238
MESH:D007644 Darier Disease Fluorouracil 4.3616733453
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.7015213294
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.2218249437
MESH:D003922 Diabetes Mellitus, Type 1 Dehydroepiandrosterone 3.5516616286
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 3.8120387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 3.8117107852
MESH:D003928 Diabetic Nephropathies Estradiol 3.0519279558
MESH:D003929 Diabetic Neuropathies Progesterone 4.0717187935
MESH:D004283 Dog Diseases Antimony 5.2212019027
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 19.6521346803 18551238
MESH:D056486 Drug-Induced Liver Injury 2-amino-4,6-dinitrotoluene 19.6521346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 19.6511834606 16393943 16227642 11739529 19416960 15619225 10915739 11529661 18071297 19164858 11461765 10663392 19739265 18713872 11287661 12153990 14986274 12392966 12705907 2444490 15968718 19923254 17522070 11743745 11421492 12594235 14725611 16485898 16781746 19420014 19085960 17562736 12958197 14550746 16081117 17906064 16109766 12540782 16177239 19370779 10774834
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 19.6519085960 7120509 15968718 3732212 17522070 6884620 4309450 3786805 2869522 6623471 7440962 7179309 10915739 19336974 21278145 10092053 16227642 11566570 9327722 15027814 16177239 15998439
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 19.6519107877
MESH:D056486 Drug-Induced Liver Injury Dimethylnitrosamine 19.658172417
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 19.6520420201
MESH:D056486 Drug-Induced Liver Injury Tetracycline 19.6517522070
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.6619426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.4411462148
MESH:D004487 Edema pirinixic acid 5.2912083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 5.2911000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 10.4818230668 15322242 16714409
MESH:D004489 Edema, Cardiac Tretinoin 10.4818230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 7.9515138306
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 7.9517692515
MESH:D016889 Endometrial Neoplasms Estradiol 6.4611473722 18566989 19148513
MESH:D016889 Endometrial Neoplasms Tretinoin 6.4616569247
MESH:D004715 Endometriosis Progesterone 7.6916134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 7.6910568697 9294722
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.6816302075
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 12.4520426865
MESH:D004938 Esophageal Neoplasms arsenic trioxide 12.4512903497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 12.4516530937
MESH:D004938 Esophageal Neoplasms Dimethylnitrosamine 12.4517016578
MESH:D004938 Esophageal Neoplasms Fluorouracil 12.4516337965 17638652 15173087 16481741 16785472
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 7.7611564622
MESH:D005124 Eye Abnormalities Tretinoin 7.769664655 16938888
MESH:D015785 Eye Diseases, Hereditary Retinoids 5.5616968212
MESH:D005234 Fatty Liver arsenic trioxide 25.7315073043
MESH:D005234 Fatty Liver Carbon Tetrachloride 25.7312631006 61145 12795759 16239168 15959796 17595544 16045604 19224547
MESH:D005234 Fatty Liver Cyclosporine 25.7319224547
MESH:D005234 Fatty Liver Diethylnitrosamine 25.7320387270 21071580
MESH:D005234 Fatty Liver pirinixic acid 25.7319236843 20131406
MESH:D005234 Fatty Liver Tetracycline 25.7316917069 19224547
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.0411858732
MESH:D005355 Fibrosis Carbon Tetrachloride 17.6818705752
MESH:D005355 Fibrosis Cyclosporine 17.6812639820 12168785
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 17.6820067830
MESH:D005355 Fibrosis Tretinoin 17.6817994277
MESH:D005391 Firesetting Behavior Testosterone 5.417506515
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.8516904648
MESH:D005756 Gastritis Acetaminophen 3.2416983495
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.798708960
MESH:D005909 Glioblastoma Testosterone 6.5517162496
MESH:D005909 Glioblastoma Tretinoin 6.5517312396
MESH:D005910 Glioma Fluorouracil 2.6916145905
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.1510696789
MESH:D006258 Head and Neck Neoplasms Fluorouracil 11.4615102660 15162350 18337622
MESH:D006258 Head and Neck Neoplasms Retinoids 11.4617368321
MESH:D006258 Head and Neck Neoplasms Tretinoin 11.4616096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.7216084493
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 9.7120471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 9.7110048152 11294989
MESH:D006330 Heart Defects, Congenital Tretinoin 9.719664655 14991402
MESH:D006333 Heart Failure pirinixic acid 2.2720558911
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 3.9915720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.9511000095
MESH:D006505 Hepatitis Carbon Tetrachloride 3.1919900420 19110552
MESH:D006529 Hepatomegaly pirinixic acid 12.0916221962 19772884 19176532 18467677
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 12.0915340226 12621046 16120746
MESH:D006529 Hepatomegaly triadimefon 12.0917178688 17178689
MESH:D006558 Herpes Genitalis Estradiol 4.5915709030
MESH:D006628 Hirsutism Testosterone 5.2117019078
MESH:D019584 Hot Flashes Estradiol 3.3217088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.6115340226 16354765 8697196 18606429 16959395
MESH:D006930 Hyperalgesia Acetaminophen 6.5016870215
MESH:D006930 Hyperalgesia Tretinoin 6.5016870215
MESH:D017588 Hyperandrogenism Testosterone 4.8717019078
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.1016899240
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.1516778211
MESH:D006943 Hyperglycemia pirinixic acid 2.8120558911
MESH:D006973 Hypertension Cyclosporine 4.3510903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 4.3518670907 18850075
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.6715338365
MESH:D007006 Hypogonadism Testosterone 4.2812002444
MESH:D007018 Hypopituitarism Testosterone 5.7617426086
MESH:D007174 Impulse Control Disorders Testosterone 5.417506515
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 3.9815869954
MESH:D007249 Inflammation Diethylnitrosamine 6.9418785209
MESH:D007249 Inflammation Progesterone 6.9415869954
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 6.9412200463 12878042
MESH:D007333 Insulin Resistance Estradiol 6.2416393666 16627594
MESH:D007333 Insulin Resistance pirinixic acid 6.2416306350
MESH:D007410 Intestinal Diseases Tretinoin 3.3517994277
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 15.0316580747
MESH:D007569 Jaw Abnormalities Tretinoin 15.0315992940 17551590
MESH:D007569 Jaw Abnormalities triadimefon 15.0315834900 15992940
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.0015604871
MESH:D007674 Kidney Diseases Acetaminophen 8.4815629191 12587719
MESH:D007674 Kidney Diseases Cyclosporine 8.488314463 10903974 18776723
MESH:D007674 Kidney Diseases Estradiol 8.4815618244
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 19.6616705839
MESH:D007680 Kidney Neoplasms Cyclosporine 19.6612371664
MESH:D007680 Kidney Neoplasms Estradiol 19.6615610895
MESH:D007680 Kidney Neoplasms Estrone 19.6615610895
MESH:D007680 Kidney Neoplasms Fluorouracil 19.6616985049
MESH:D007859 Learning Disorders sevoflurane 4.3519212262
MESH:D007896 Leishmaniasis Antimony 4.4510953559 15220340 21063981 12019027 21182181
MESH:D016773 Leishmaniasis, Cutaneous Antimony 4.3211475954 19141829 8889330
MESH:D007897 Leishmaniasis, Mucocutaneous Antimony 5.069643325 7854095 10651420 10881086 11370249
MESH:D007898 Leishmaniasis, Visceral Antimony 7.6411105143 7554475 8142506 1899875 20495762 7854095 7875148
MESH:D007898 Leishmaniasis, Visceral Antimony Potassium Tartrate 7.6412707265
MESH:D007938 Leukemia arsenic trioxide 5.5915070760
MESH:D007938 Leukemia Tretinoin 5.5917143497
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.4117077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 3.8816972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.1114633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 13.9719077051
MESH:D007951 Leukemia, Myeloid Retinoids 13.9716482212
MESH:D007951 Leukemia, Myeloid Tretinoin 13.9716482212 16932348 19285840
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 3.5716467208 20471514 17050201 16968895 19850784
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 3.5717596541 16294345 19850784
MESH:D015473 Leukemia, Promyelocytic, Acute Antimony Potassium Tartrate 11.249834237
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 11.2419225113 15213294 15336539 19035177 11161223 19642359 15622746 17107899 17217047 17712046 16966277 17649720 16331271 12712474 12018890 16823087 12679006 19075265 17869043 16891316 15748426 9834237 16330433 11468182 16112521
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 11.2416766008 9834237 17368321 19035177 12679006 17107899 19029980 19075265 17301526 17361223 17217047 17339181 16331271 17294898 15748426 16823087 16140955 19642359 17506722 16788101 19225113 17649720 16935935 17712046 16891316
MESH:D015458 Leukemia, T-Cell arsenic trioxide 3.9416882451
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.009224671
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 5.7916943688 17174718 11408273 17157831 21278145 16239168 11903743 16221502 17334410
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 5.7918665156 18407596 20032147 19638242 18522880
MESH:D008106 Liver Cirrhosis, Experimental marker/mechanism 17072980
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 7.8817944888 12958196 18705752 18429990 15057751 18418968 17900296 17565644 11481614 17525996 14724832 12667390 16033810 12609069 18166357 18395095 20821823 17640975 16097048 12445421 18481824 15876570 14716496 18420326 15730626 16027843 17481882 12741479 16638106 15996030 18054572 17766677 15370692 12632512 18472332 16192424 17869086 15650968 16136751 15362042 17698563 15959796 18412020 15052691 17557913 15893842 18472094 16116963 17708605 17631135 15931870 14716833 17714472 18263696 17761835 12586293 18006644 18339082 12445418 18156304 18210741 10355542 17823541 17721639 14512876 18279442 16015684 18317297 12389079 15123356 18251166 18205269 12632514 13678700 17922224 16011737 18277467 18187930 15338365 17976157 12898905 15925388 14748882 15673190 12666154 14620537 18376398 15818738 17805973 18395914 12649538 12546737 16248980
MESH:D008106 Liver Cirrhosis, Experimental Dimethylnitrosamine 7.8818637143 15366600 17201889 15479170 17198567 12918455 15369754 17719030 16009107 17036385 14568256 15086199 14726149 17881167 16169303 15942678 17534399 15081153 18567088 15138612 15571005 17432682 18629640 15763062 18239293 15067225 15504291 15099470 15798949 18210741 15383259 15733078 15793283 15864749 16627068 14659978 14643895 15492853 17724770 15842777 15744066 18672772 15577212 17640959 15591649 15298665 16603200 16270385 16570917 14709902 15723089 18237412 15161499 17465448 17203207 18371158 18095165 17196135 17666798 16042886 17348192 18364076 12925901 15339415 16544323
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 7.8814659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 7.8815474484
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 7.8812878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 7.8818397230 16248980
MESH:D008107 Liver Diseases Acetaminophen 8.3412969438 16611625 19014921 12587719 19460945 11587558 16610002 19784758
MESH:D008107 Liver Diseases Carbon Tetrachloride 8.3415720792 16964402 16246199 17285989 15830285
MESH:D008107 Liver Diseases Diethylnitrosamine 8.3417034775
MESH:D008107 Liver Diseases triadimefon 8.3419363144
MESH:D017093 Liver Failure Carbon Tetrachloride 3.7415123358
MESH:D017114 Liver Failure, Acute Acetaminophen 14.1016871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 14.1014706259 16899240
MESH:D017114 Liver Failure, Acute Dimethylnitrosamine 14.1017457977
MESH:D008113 Liver Neoplasms 2,4,5,2',4',5'-hexachlorobiphenyl 42.9416835634 18644402
MESH:D008113 Liver Neoplasms Aflatoxin B1 42.949163691 18177683 2125692 15890375
MESH:D008113 Liver Neoplasms arsenic trioxide 42.9414682389
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 42.9421137059 20195826
MESH:D008113 Liver Neoplasms beta-Naphthoflavone 42.9419389873 21295105
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 42.9419294768
MESH:D008113 Liver Neoplasms Dehydroepiandrosterone 42.9418709148
MESH:D008113 Liver Neoplasms Diethylnitrosamine 42.9421167192 12771043 9163691 21278145 20434301 19426721 19850985 18648771 19256749 12112319 2862719 18754104 19551842 19812893 19255062 19499222 2422723 19996281 19090486 19690152 21071580 18977376 19073162 19638242 20492335 20452335 10737359 19294768 15885732 15175105 20583210 20101389 20501860 18644402 20405173 19254457 19642983 20137499 20118626 19833225 18978307 19427195 16942905 21047994
MESH:D008113 Liver Neoplasms Dimethylnitrosamine 42.9415890375 3113478
MESH:D008113 Liver Neoplasms Fluorouracil 42.9415113037 17045692 16603448 18383874
MESH:D008113 Liver Neoplasms pirinixic acid 42.9420007298 15890375 16377806
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 42.9416984957
MESH:D008113 Liver Neoplasms triadimefon 42.9419028983
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 37.718603461
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 37.7120377131
MESH:D008114 Liver Neoplasms, Experimental beta-Naphthoflavone 37.7118164116
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 37.7112014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Dehydroepiandrosterone 37.718603461
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 37.7118093689 18775883 19126423 19539802 3124819 19009564 17174075 16267830 21159647 18544905 17942915 18079962 17854601 19519916 2563599 18308698 18282651 18164116 16842330 9362446 18253720 19004024
MESH:D008114 Liver Neoplasms, Experimental Dimethylnitrosamine 37.7115603536 1848544 6150874
MESH:D008114 Liver Neoplasms, Experimental Hexachlorobenzene 37.711423854
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 37.7112151625
MESH:D008114 Liver Neoplasms, Experimental triadimefon 37.7117178689
MESH:D008133 Long QT Syndrome arsenic trioxide 3.0215213294
MESH:D008175 Lung Neoplasms Aflatoxin B1 11.8314755239
MESH:D008175 Lung Neoplasms arsenic trioxide 11.8311798837 19825857
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 11.8320869020 18569708 17053015 18816296 20064080 20464547 20135361 18520028 6695378
MESH:D008175 Lung Neoplasms bexarotene 11.8317849452
MESH:D008175 Lung Neoplasms Diethylnitrosamine 11.8321163286 20970405 6695378 20512841
MESH:D008175 Lung Neoplasms Dimethylnitrosamine 11.8316061637 19555203 11884234
MESH:D008175 Lung Neoplasms Fluorouracil 11.8315246190
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 11.8319555203 11884234
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.3615086387
MESH:D016410 Lymphoma, T-Cell, Cutaneous bexarotene 4.7211161223
MESH:D008325 Mammary Neoplasms, Experimental bexarotene 12.0419196722 15591091 19196723
MESH:D008325 Mammary Neoplasms, Experimental Dehydroepiandrosterone 12.0416457693
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 12.0416891317 11807958 17203775 11408345
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 12.0417203775 11408345
MESH:D020149 Manganese Poisoning Estradiol 4.0419453300
MESH:D008415 Mastocytosis Retinoids 6.1516953078
MESH:D008527 Medulloblastoma Tretinoin 2.6017453147
MESH:D008545 Melanoma Tretinoin 1.8816752155
MESH:D008546 Melanoma, Experimental Acetaminophen 3.1519513568
MESH:D008569 Memory Disorders sevoflurane 4.3419212262
MESH:D008591 Meningomyelocele Tretinoin 4.0016940565
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.3516801185
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 7.4316381670
MESH:D009062 Mouth Neoplasms Fluorouracil 7.4316757204 18986760
MESH:D009101 Multiple Myeloma arsenic trioxide 2.8019417148 11468182 15949261 14977855 19549372
MESH:D009135 Muscular Diseases pirinixic acid 3.0916239165
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.2318349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 6.5416105982 16882451
MESH:D009190 Myelodysplastic Syndromes Tretinoin 6.5417596541
MESH:D009203 Myocardial Infarction pirinixic acid 1.9619151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.6812213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 7.1516810080
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 7.1516411023
MESH:D009336 Necrosis 2,4-dinitrotoluene 3.4318551238
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.5516624393
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 2.393581430 9029167
MESH:D009369 Neoplasms 2,4,5,2',4',5'-hexachlorobiphenyl 13.348820588
MESH:D009369 Neoplasms Benzo(a)pyrene 13.3411141357
MESH:D009369 Neoplasms Fluorouracil 13.3418600527 18239605 16928823
MESH:D009369 Neoplasms pirinixic acid 13.3417405874
MESH:D009369 Neoplasms Tretinoin 13.3416594593 16946489
MESH:D009376 Neoplasms, Hormone-Dependent bexarotene 4.3519196722
MESH:D009389 Neovascularization, Pathologic Estradiol 3.3017289903
MESH:D009395 Nephritis, Interstitial Tetracycline 4.359884423
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.0017954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 2.9218481113 19348381
MESH:D009421 Nervous System Malformations Estradiol 13.9611399458 16427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 13.9614600291
MESH:D009421 Nervous System Malformations Tretinoin 13.969125849
MESH:D009436 Neural Tube Defects arsenic trioxide 6.3510525206
MESH:D009436 Neural Tube Defects Tretinoin 6.359142499
MESH:D019636 Neurodegenerative Diseases Acetaminophen 7.0218514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 7.0220387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.6820387270
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.1416436463
MESH:D009765 Obesity pirinixic acid 1.7020558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 3.0616049721 12819281
MESH:D015663 Osteoporosis, Postmenopausal Dehydroepiandrosterone 4.6316397352
MESH:D010051 Ovarian Neoplasms arsenic trioxide 10.0312452020 19769630 16624393
MESH:D010051 Ovarian Neoplasms Estradiol 10.0319401270
MESH:D010051 Ovarian Neoplasms Progesterone 10.0316525653 17393432
MESH:D010051 Ovarian Neoplasms Tretinoin 10.0316936753
MESH:D010146 Pain Acetaminophen 5.4516870215
MESH:D010146 Pain Tretinoin 5.4516870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 10.9215580305
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 10.9216540662
MESH:D010190 Pancreatic Neoplasms Fluorouracil 10.9215113037 16929163 16500647 19003803
MESH:D010190 Pancreatic Neoplasms Tretinoin 10.9215976015
MESH:D010235 Paraganglioma arsenic trioxide 3.7619927285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.8112520081
MESH:D010391 Pemphigoid, Bullous Tetracycline 4.9911026799
MESH:D010409 Penile Diseases Antimony 5.319643325
MESH:D010493 Pericarditis Antimony 5.6820465667
MESH:D017119 Porphyria Cutanea Tarda Hexachlorobenzene 9.749918132
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 9.7418163543
MESH:D011230 Precancerous Conditions Cyclosporine 7.7412371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 7.742563599
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 2.7611399792 11896295 11222880 11118676
MESH:D017096 Prion Diseases Tetracycline 4.9810903871
MESH:D011470 Prostatic Hyperplasia Calcitriol 4.3515572423
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 9.5820887781
MESH:D019048 Prostatic Intraepithelial Neoplasia Testosterone 9.5820887781
MESH:D011471 Prostatic Neoplasms 2-methoxyestradiol 2.0316356831
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.0319131511
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.0317292933
MESH:D011471 Prostatic Neoplasms Calcitriol 2.0316289102 12479363 15754350 16644109 18247401
MESH:D011471 Prostatic Neoplasms Estradiol 2.0316740699
MESH:D011471 Prostatic Neoplasms Fluorouracil 2.0319082440 18626508
MESH:D011471 Prostatic Neoplasms Retinoids 2.0316724957 16166285
MESH:D011507 Proteinuria Tretinoin 3.2116636307
MESH:D011565 Psoriasis Cyclosporine 2.0716882103
MESH:D011625 Pterygium Tretinoin 4.3616723453
MESH:D012004 Rectal Neoplasms Fluorouracil 3.6516160472 18286688 18722050 15538739
MESH:D015427 Reperfusion Injury pirinixic acid 2.1719058328
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.4318990726
MESH:D012208 Rhabdomyosarcoma Tretinoin 3.7016116481 16283617
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.6918045962
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 3.5516646077
MESH:D012640 Seizures 2,4-dinitrotoluene 2.2518551238
MESH:D012735 Sexual Dysfunction, Physiological Testosterone 5.7616631401
MESH:D012871 Skin Diseases monomethylarsonous acid 3.2617431481
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 15.6510029692 19755658
MESH:D012878 Skin Neoplasms Retinoids 15.6517538947
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 15.658532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 15.6516192470
MESH:D012878 Skin Neoplasms Tretinoin 15.6516467112
MESH:D013119 Spinal Cord Injuries Progesterone 3.8515862959 16503802
MESH:D013158 Splenic Diseases Dimethylnitrosamine 4.8312587719
MESH:D013274 Stomach Neoplasms arsenic trioxide 7.5917007042
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 7.5920155912 2093021
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 7.5918456281
MESH:D013274 Stomach Neoplasms Dimethylnitrosamine 7.5916033868
MESH:D013274 Stomach Neoplasms Fluorouracil 7.5915786421 18396642 19084572 16424979 17172411 17522103 19015929 17498489 16951190 18567086
MESH:D013274 Stomach Neoplasms Tretinoin 7.5917261132
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.4612697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 19.0419014326
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 19.047505956
MESH:D013964 Thyroid Neoplasms Retinoids 19.0416940797
MESH:D013964 Thyroid Neoplasms Tretinoin 19.0416026305 17045167
MESH:D013964 Thyroid Neoplasms triadimefon 19.0417178689
MESH:D013978 Tibial Fractures Estradiol 4.2519048282
MESH:D014062 Tongue Neoplasms Fluorouracil 8.5916280240
MESH:D014062 Tongue Neoplasms Tretinoin 8.5916051514
MESH:D016171 Torsades de Pointes arsenic trioxide 3.5315213294
MESH:D014352 Trypanosomiasis Antimony 5.4915220340
MESH:D014376 Tuberculosis Tretinoin 2.9516040207
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 10.4416049721
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 10.4411780464 20435036 12845720 12973940
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 10.4417053015
MESH:D001749 Urinary Bladder Neoplasms monomethylarsonous acid 10.4420375083
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 3.8810091137
MESH:D014581 Urticaria Acetaminophen 2.5810982225
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 8.2116803524
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 8.2116129372
MESH:D014604 Uveal Neoplasms Tretinoin 4.1716752155
MESH:D014605 Uveitis Cyclosporine 3.541336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.1512125929
MESH:D014820 Vitiligo Tretinoin 3.6516761959
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.8115886252
MESH:D009396 Wilms Tumor Tretinoin 3.6016287080
MESH:D014985 Xerophthalmia Cyclosporine 4.0017120751
Pathway ID Pathway Name
KEGG:01100 Metabolic pathways
KEGG:00140 Steroid hormone biosynthesis
Pharmacogenomics Knowledge Base Top
Drug Bank Top
Drugbank ID Action Drug Name Description
DB00157 - NADH Dietary supplement;Micronutrient
No data
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved