AutismKB 2.0

Annotation Detail for HSPA1A


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Basic Information Top
Gene Symbol:HSPA1A ( FLJ54303,FLJ54370,FLJ54392,FLJ54408,FLJ75127,HSP70-1,HSP70-1A,HSP70I,HSP72,HSPA1,HSPA1B )
Gene Full Name: heat shock 70kDa protein 1A
Band: 6p21.33
Quick LinksEntrez ID:3303; OMIM: 140550; Uniprot ID:HSP71_HUMAN; ENSEMBL ID: ENSG00000204389; HGNC ID: 5232
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04010MAPK signaling pathway
hsa03040Spliceosome
hsa04141Protein processing in endoplasmic reticulum
hsa04144Endocytosis
hsa05145Toxoplasmosis
hsa04612Antigen processing and presentation
hsa05020Prion diseases
No data
Pathway IDPathway Name
200120FOXM1 transcription factor network
200101Direct p53 effectors
Pathway IDPathway Name
P00049Parkinson disease
P00006Apoptosis signaling pathway
Pathway IDPathway Name
500695Viral RNP Complexes in the Host Cell Nucleus
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1758Common cold
1831Prostate cancer
1817Respiratory failure
1902Kidney failure
1904Diabetes mellitus
2022Liver cancer
2053Colon cancer
2074Asthma
Desease Name
AGING
Alzheimer's disease
kidney transplant
Hearing Loss, Noise-Induced
RENAL
NEUROLOGICAL
clozapine-induced agranulocytosis
high-altitude illness
sepsis
preeclampsia
REPRODUCTION
Dementia
longevity
INFECTION
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C028474 1,4-bis(2-(3,5-dichloropyridyloxy))benzene 1,4-bis(2-(3,5-dichloropyridyloxy))benzene affects the expression of HSPA1A mRNAaffects expression 18281256
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of HSPA1A mRNAaffects expression 21346803
C472791 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid results in increased expression of HSPA1A mRNAincreases expression 16788091
C075773 4-phenylbutyric acid 4-phenylbutyric acid results in increased expression of HSPA1A mRNAincreases expression 14583596
D000082 Acetaminophen Acetaminophen affects the expression of HSPA1A mRNAaffects expression 17562736
D000082 Acetaminophen Acetaminophen results in increased expression of HSPA1A mRNAincreases expression 11743745
D000082 Acetaminophen PTGS2 protein affects the reaction [Acetaminophen results in increased expression of HSPA1A mRNA]affects reaction|increases expression 11743745
D000082 Acetaminophen Acetaminophen affects the expression of HSPA1A mRNAaffects expression 19784758
18246545
D000082 Acetaminophen Acetaminophen results in decreased expression of HSPA1A mRNAdecreases expression 19784758
D000082 Acetaminophen Acetaminophen results in increased expression of HSPA1A mRNAincreases expression 17522070
19784758
18246545
17202762
D000082 Acetaminophen Acetaminophen results in increased expression of HSPA1A proteinincreases expression 15690153
D000643 Ammonium Chloride Ammonium Chloride affects the expression of HSPA1A mRNAaffects expression 16483693
D003913 Dextroamphetamine Dextroamphetamine results in increased expression of HSPA1A mRNAincreases expression 19194377
D001151 Arsenic Arsenic results in decreased expression of HSPA1A mRNAdecreases expression 19654921
C006632 arsenic trioxide arsenic trioxide affects the expression of HSPA1A mRNAaffects expression 12749819
C006632 arsenic trioxide arsenic trioxide results in increased expression of HSPA1A mRNAincreases expression 19417148
18081892
20458559
C006632 arsenic trioxide arsenic trioxide results in increased expression of HSPA1A proteinincreases expression 19364129
C015001 arsenite [arsenite co-treated with Benzo(a)pyrene] results in increased expression of HSPA1A mRNAaffects cotreatment|increases expression 15894712
C015001 arsenite arsenite results in increased expression of HSPA1A mRNAincreases expression 15894712
D017638 Asbestos, Crocidolite Asbestos, Crocidolite results in increased expression of HSPA1A mRNAincreases expression 18687144
D001205 Ascorbic Acid [Quercetin co-treated with Ascorbic Acid] results in increased expression of HSPA1A mRNAaffects cotreatment|increases expression 17639512
D001554 Benzene Benzene results in decreased expression of HSPA1A mRNAdecreases expression 15929907
D019324 beta-Naphthoflavone [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of HSPA1A mRNAaffects cotreatment|increases expression 18164116
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of HSPA1A mRNAincreases expression 20106945
D001564 Benzo(a)pyrene [arsenite co-treated with Benzo(a)pyrene] results in increased expression of HSPA1A mRNAaffects cotreatment|increases expression 15894712
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of HSPA1A mRNAincreases expression 15894712
C072553 benzyloxycarbonylleucyl-leucyl-leucine aldehyde benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HSPA1A proteinincreases expression 18331584
C072553 benzyloxycarbonylleucyl-leucyl-leucine aldehyde PARK7 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HSPA1A protein]affects reaction|increases expression 18331584
C099952 bifenthrin bifenthrin results in decreased expression of HSPA1A proteindecreases expression 16271832
C006780 bisphenol A bisphenol A results in increased expression of HSPA1A proteinincreases expression 12460799
C006780 bisphenol A bisphenol A results in increased expression of HSPA1A mRNAincreases expression 17010207
C005961 bis(tri-n-butyltin)oxide bis(tri-n-butyltin)oxide results in increased expression of HSPA1A mRNAincreases expression 17553608
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in increased expression of HSPA1A mRNAincreases expression 12414654
D002104 Cadmium Cadmium results in increased expression of HSPA1A mRNAincreases expression 11985888
D002104 Cadmium Cadmium promotes the reaction [HSF1 protein binds to HSPA1A enhancer]affects binding|increases reaction 16460681
D002104 Cadmium Cadmium promotes the reaction [HSF1 protein binds to HSPA1A promoter]affects binding|increases reaction 17244614
D002104 Cadmium Cadmium results in increased expression of HSPA1A mRNAincreases expression 17244614
21172416
D002104 Cadmium Cadmium results in increased expression of HSPA1A proteinincreases expression 16729991
D002104 Cadmium Cadmium results in increased expression of HSPA1A proteinincreases expression 16729991
D019256 Cadmium Chloride Cadmium Chloride results in increased expression of HSPA1A mRNAincreases expression 11985888
D019256 Cadmium Chloride Cadmium Chloride results in increased expression of HSPA1A proteinincreases expression 15734587
D019256 Cadmium Chloride Cadmium Chloride results in increased expression of HSPA1A proteinincreases expression 16729991
D019256 Cadmium Chloride Cadmium Chloride results in increased expression of HSPA1A proteinincreases expression 16729991
C037123 cadmium sulfate cadmium sulfate promotes the reaction [HSF1 protein binds to HSPA1A enhancer]affects binding|increases reaction 16460681
C037123 cadmium sulfate cadmium sulfate promotes the reaction [HSF1 protein binds to HSPA1A promoter]affects binding|increases reaction 17244614
C037123 cadmium sulfate cadmium sulfate results in increased expression of HSPA1A mRNAincreases expression 17244614
C459604 candoxin candoxin results in increased expression of HSPA1A mRNAincreases expression 16309724
D002220 Carbamazepine HSPA1A gene SNP affects the susceptibility to Carbamazepineaffects response to substance 16538175
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of HSPA1A mRNAaffects expression 17484886
D002251 Carbon Tetrachloride Carbon Tetrachloride results in decreased expression of HSPA1A proteindecreases expression 12629582
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of HSPA1A mRNAincreases expression 17522070
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of HSPA1A proteinincreases expression 15690153
16845489
D002259 Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of HSPA1A mRNAdecreases expression 16039398
D002351 Carrageenan Carrageenan results in increased expression of HSPA1A proteinincreases expression 15860553
C016299 chelerythrine chelerythrine inhibits the reaction [sodium arsenite results in increased expression of HSPA1A protein]decreases reaction|increases expression 12690470
D020111 Chlorodiphenyl (54% Chlorine) Chlorodiphenyl (54% Chlorine) results in increased expression of HSPA1A mRNAincreases expression 17851650
D002725 Chloroform Chloroform results in increased expression of HSPA1A mRNAincreases expression 17522070
D003300 Copper Copper results in increased expression of HSPA1A mRNAincreases expression 17244614
D019327 Copper Sulfate Copper Sulfate results in increased expression of HSPA1A mRNAincreases expression 16730829
17244614
D003375 Coumestrol Coumestrol results in increased expression of HSPA1A proteinincreases expression 12460799
C029892 cupric chloride cupric chloride results in increased expression of HSPA1A proteinincreases expression 15734587
D003520 Cyclophosphamide Cyclophosphamide affects the expression of HSPA1A mRNAaffects expression 18246545
D016572 Cyclosporine Cyclosporine results in increased expression of HSPA1A mRNAincreases expression 20106945
D013759 Tetrahydrocannabinol Tetrahydrocannabinol results in decreased expression of HSPA1A mRNAdecreases expression 16039398
D003907 Dexamethasone Dexamethasone results in increased expression of HSPA1A mRNAincreases expression 17522070
D016190 Carboplatin Carboplatin results in increased expression of HSPA1A mRNAincreases expression 18172885
D002945 Cisplatin Cisplatin results in decreased expression of HSPA1A proteindecreases expression 12690470
D002945 Cisplatin Cisplatin results in increased expression of HSPA1A mRNAincreases expression 18172885
D002945 Cisplatin sodium arsenite inhibits the reaction [Cisplatin results in decreased expression of HSPA1A protein]decreases expression|decreases reaction 12690470
D002945 Cisplatin uranyl acetate inhibits the reaction [Cisplatin results in decreased expression of HSPA1A protein]decreases expression|decreases reaction 12690470
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of HSPA1A mRNAaffects cotreatment|increases expression 18164116
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of HSPA1A mRNAaffects cotreatment|decreases expression 18544905
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with kojic acid] results in increased expression of HSPA1A mRNAaffects cotreatment|increases expression 18544905
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of HSPA1A proteinincreases expression 12460799
C039353 dihydroxyethyldithiocarbamate Dizocilpine Maleate inhibits the reaction [[Kainic Acid co-treated with dihydroxyethyldithiocarbamate] results in increased expression of HSPA1A protein]affects cotreatment|decreases reaction|increases expression 16686654
C039353 dihydroxyethyldithiocarbamate GYKI 52466 inhibits the reaction [[Kainic Acid co-treated with dihydroxyethyldithiocarbamate] results in increased expression of HSPA1A protein]affects cotreatment|decreases reaction|increases expression 16686654
C039353 dihydroxyethyldithiocarbamate [Kainic Acid co-treated with dihydroxyethyldithiocarbamate] results in increased expression of HSPA1A proteinaffects cotreatment|increases expression 16686654
C067354 dimethyladipate dimethyladipate results in increased expression of HSPA1A proteinincreases expression 15690153
D004178 Diquat Diquat results in increased expression of HSPA1A mRNAincreases expression 21172416
D016291 Dizocilpine Maleate Dizocilpine Maleate inhibits the reaction [[Kainic Acid co-treated with dihydroxyethyldithiocarbamate] results in increased expression of HSPA1A protein]affects cotreatment|decreases reaction|increases expression 16686654
D004317 Doxorubicin Doxorubicin results in increased expression of HSPA1A proteinincreases expression 16495754
16210442
D004317 Doxorubicin Doxorubicin results in increased expression of HSPA1A proteinincreases expression 15810080
D004391 Dust Dust results in increased expression of HSPA1A mRNAincreases expression 17805423
D004958 Estradiol Estradiol results in increased expression of HSPA1A mRNAincreases expression 20106945
D004958 Estradiol Estradiol results in increased expression of HSPA1A proteinincreases expression 15860553
D000431 Ethanol Ethanol results in increased expression of HSPA1A mRNAincreases expression 17189318
D000431 Ethanol Ethanol results in increased expression of HSPA1A proteinincreases expression 17189318
D000431 Ethanol geranylgeranylacetone promotes the reaction [Ethanol results in increased expression of HSPA1A protein]increases expression|increases reaction 17189318
D000431 Ethanol HSF1 protein affects the reaction [Ethanol results in increased expression of HSPA1A mRNA]affects reaction|increases expression 17189318
D000431 Ethanol HSF1 protein affects the reaction [Ethanol results in increased expression of HSPA1A protein]affects reaction|increases expression 17189318
D004997 Ethinyl Estradiol Ethinyl Estradiol inhibits the reaction [IL1B protein results in increased expression of HSPA1A mRNA]decreases reaction|increases expression 12072388
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of HSPA1A mRNAaffects cotreatment|increases expression 17942748
C100163 formetanate formetanate results in decreased expression of HSPA1A proteindecreases expression 16271832
C038958 gadolinium chloride gadolinium chloride inhibits the reaction [Thioacetamide results in increased expression of HSPA1A mRNA]decreases reaction|increases expression 12963478
C038958 gadolinium chloride gadolinium chloride inhibits the reaction [Thioacetamide results in increased expression of HSPA1A protein]decreases reaction|increases expression 12963478
C106014 gedunin gedunin results in increased expression of HSPA1A mRNAincreases expression 17010675
C001277 geldanamycin geldanamycin results in increased expression of HSPA1A proteinincreases expression 11448926
C001277 geldanamycin geldanamycin results in increased expression of HSPA1A mRNAincreases expression 19723345
C001277 geldanamycin geldanamycin results in increased expression of HSPA1A proteinincreases expression 19723345
C001277 geldanamycin [geldanamycin results in increased expression of HSPA1A protein] which results in decreased susceptibility to Gentamicinsdecreases response to substance|increases expression 19723345
D019833 Genistein Genistein results in increased expression of HSPA1A mRNAincreases expression 17010207
D005839 Gentamicins Gentamicins results in increased expression of HSPA1A mRNAincreases expression 16538044
D005839 Gentamicins [geldanamycin results in increased expression of HSPA1A protein] which results in decreased susceptibility to Gentamicinsdecreases response to substance|increases expression 19723345
D005839 Gentamicins Gentamicins results in increased expression of HSPA1A mRNAincreases expression 17043427
18172885
C031049 geranylgeranylacetone geranylgeranylacetone promotes the reaction [Ethanol results in increased expression of HSPA1A protein]increases expression|increases reaction 17189318
C061950 GYKI 52466 GYKI 52466 inhibits the reaction [[Kainic Acid co-treated with dihydroxyethyldithiocarbamate] results in increased expression of HSPA1A protein]affects cotreatment|decreases reaction|increases expression 16686654
D006861 Hydrogen Peroxide Hydrogen Peroxide promotes the reaction [HSPA1A protein binds to HMGB1 protein]affects binding|increases reaction 17513788
D006861 Hydrogen Peroxide Hydrogen Peroxide results in increased expression of HSPA1A mRNAincreases expression 12414654
D006861 Hydrogen Peroxide HSPA1A protein inhibits the reaction [Hydrogen Peroxide affects the localization of HMGB1 protein]affects localization|decreases reaction 17513788
D006861 Hydrogen Peroxide HSPA1A protein inhibits the reaction [Hydrogen Peroxide results in increased secretion of HMGB1 protein]decreases reaction|increases secretion 17513788
D006861 Hydrogen Peroxide Hydrogen Peroxide affects the localization of HSPA1A proteinaffects localization 17513788
D006861 Hydrogen Peroxide Hydrogen Peroxide promotes the reaction [HSPA1A protein binds to HMGB1 protein]affects binding|increases reaction 17513788
D006861 Hydrogen Peroxide Quercetin inhibits the reaction [Hydrogen Peroxide affects the localization of HSPA1A protein]affects localization|decreases reaction 17513788
D006861 Hydrogen Peroxide Quercetin inhibits the reaction [Hydrogen Peroxide promotes the reaction [HSPA1A protein binds to HMGB1 protein]]affects binding|decreases reaction|increases reaction 17513788
C013038 hydroxyhydroquinone hydroxyhydroquinone results in increased expression of HSPA1A mRNAincreases expression 17572062
D007052 Ibuprofen Ibuprofen affects the localization of HSPA1A proteinaffects localization 16239242
D007052 Ibuprofen Ibuprofen results in increased expression of HSPA1A proteinincreases expression 16239242
D007213 Indomethacin Indomethacin affects the localization of HSPA1A proteinaffects localization 16239242
D007213 Indomethacin Indomethacin results in increased expression of HSPA1A proteinincreases expression 16239242
D007608 Kainic Acid Dizocilpine Maleate inhibits the reaction [[Kainic Acid co-treated with dihydroxyethyldithiocarbamate] results in increased expression of HSPA1A protein]affects cotreatment|decreases reaction|increases expression 16686654
D007608 Kainic Acid GYKI 52466 inhibits the reaction [[Kainic Acid co-treated with dihydroxyethyldithiocarbamate] results in increased expression of HSPA1A protein]affects cotreatment|decreases reaction|increases expression 16686654
D007608 Kainic Acid [Kainic Acid co-treated with dihydroxyethyldithiocarbamate] results in increased expression of HSPA1A proteinaffects cotreatment|increases expression 16686654
C011890 kojic acid [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of HSPA1A mRNAaffects cotreatment|decreases expression 18544905
C011890 kojic acid [Diethylnitrosamine co-treated with kojic acid] results in increased expression of HSPA1A mRNAaffects cotreatment|increases expression 18544905
C029891 lead chloride lead chloride results in increased expression of HSPA1A proteinincreases expression 15734587
D001556 Lindane Lindane affects the localization of HSPA1A proteinaffects localization 12919956
C482199 lipopolysaccharide, E coli O55-B5 lipopolysaccharide, E coli O55-B5 results in decreased expression of HSPA1A proteindecreases expression 15723751
D008627 Mercuric Chloride Mercuric Chloride promotes the reaction [HSF1 protein binds to HSPA1A promoter]affects binding|increases reaction 17244614
D008627 Mercuric Chloride Mercuric Chloride results in increased expression of HSPA1A mRNAincreases expression 17244614
D008628 Mercury Mercury promotes the reaction [HSF1 protein binds to HSPA1A promoter]affects binding|increases reaction 17244614
D008628 Mercury Mercury results in increased expression of HSPA1A mRNAincreases expression 17244614
D008724 Methomyl Methomyl results in decreased expression of HSPA1A proteindecreases expression 16271832
D008731 Methoxychlor Methoxychlor results in increased expression of HSPA1A proteinincreases expression 12460799
D008769 Methylnitronitrosoguanidine Methylnitronitrosoguanidine results in decreased expression of HSPA1A mRNAdecreases expression 15120970
C035359 monorden monorden analog results in increased expression of HSPA1A proteinincreases expression 11448926
C035359 monorden monorden results in increased expression of HSPA1A proteinincreases expression 11448926
D009020 Morphine Morphine results in increased expression of HSPA1A mRNAincreases expression 15497504
D009020 Morphine Morphine results in increased expression of HSPA1A proteinincreases expression 15497504
D009020 Morphine Naloxone inhibits the reaction [Morphine results in increased expression of HSPA1A mRNA]decreases reaction|increases expression 15497504
D009270 Naloxone Naloxone inhibits the reaction [Morphine results in increased expression of HSPA1A mRNA]decreases reaction|increases expression 15497504
D015058 1-Naphthylisothiocyanate 1-Naphthylisothiocyanate results in increased expression of HSPA1A mRNAincreases expression 17522070
C022838 nickel chloride nickel chloride results in increased expression of HSPA1A mRNAincreases expression 12839937
D009578 Nitrobenzenes Nitrobenzenes analog results in decreased expression of HSPA1A mRNAdecreases expression 19784758
C025256 nonylphenol nonylphenol results in increased expression of HSPA1A mRNAincreases expression 17010207
D009853 Omeprazole Omeprazole results in decreased expression of HSPA1A mRNAdecreases expression 15223672
D009853 Omeprazole Omeprazole results in decreased expression of HSPA1A proteindecreases expression 15223672
D010126 Ozone Ozone results in increased expression of HSPA1A mRNAincreases expression 16716893
D010126 Ozone Ozone results in increased expression of HSPA1A proteinincreases expression 16716893
C005435 phenylmethylpyrazolone phenylmethylpyrazolone results in decreased expression of HSPA1A mRNAdecreases expression 19338546
19694712
C005435 phenylmethylpyrazolone phenylmethylpyrazolone results in decreased expression of HSPA1A proteindecreases expression 19694712
19338546
C011994 pirimicarb pirimicarb results in decreased expression of HSPA1A proteindecreases expression 16271832
C006253 pirinixic acid NCF1 protein promotes the reaction [pirinixic acid results in decreased expression of HSPA1A mRNA]decreases expression|increases reaction 17950772
C006253 pirinixic acid pirinixic acid results in decreased expression of HSPA1A mRNAdecreases expression 17950772
C006253 pirinixic acid pirinixic acid results in increased expression of HSPA1A mRNAincreases expression 18301758
C061957 polaprezinc polaprezinc results in increased expression of HSPA1A proteinincreases expression 16949620
D011374 Progesterone Progesterone affects the expression of HSPA1A proteinaffects expression 16797538
C031280 pyrazole pyrazole results in increased expression of HSPA1A mRNAincreases expression 17945193
D011794 Quercetin [Quercetin co-treated with Ascorbic Acid] results in increased expression of HSPA1A mRNAaffects cotreatment|increases expression 17639512
D011794 Quercetin Quercetin results in decreased expression of HSPA1A proteindecreases expression 17234771
D011794 Quercetin Quercetin affects the expression of HSPA1A proteinaffects expression 14606951
D011794 Quercetin Quercetin inhibits the reaction [Hydrogen Peroxide affects the localization of HSPA1A protein]affects localization|decreases reaction 17513788
D011794 Quercetin Quercetin inhibits the reaction [Hydrogen Peroxide promotes the reaction [HSPA1A protein binds to HMGB1 protein]]affects binding|decreases reaction|increases reaction 17513788
D011794 Quercetin Quercetin inhibits the reaction [sodium arsenite results in increased expression of HSPA1A protein]decreases reaction|increases expression 14606951
D011794 Quercetin Quercetin results in decreased expression of HSPA1A mRNAdecreases expression 17349211
D015125 Oxyquinoline Oxyquinoline affects the localization of HSPA1A proteinaffects localization 16239242
D015125 Oxyquinoline Oxyquinoline results in increased expression of HSPA1A proteinincreases expression 16239242
D020849 Raloxifene Raloxifene affects the expression of HSPA1A mRNAaffects expression 14699072
D020849 Raloxifene Raloxifene results in increased expression of HSPA1A proteinincreases expression 15860553
C064116 S-(1,1,2,2-tetrafluoroethyl)cysteine S-(1,1,2,2-tetrafluoroethyl)cysteine results in increased expression of HSPA1A mRNAincreases expression 16678137
C064116 S-(1,1,2,2-tetrafluoroethyl)cysteine S-(1,1,2,2-tetrafluoroethyl)cysteine results in increased expression of HSPA1A proteinincreases expression 16678137
C515055 S-(dimethylarsino)-glutathione S-(dimethylarsino)-glutathione results in increased expression of HSPA1A mRNAincreases expression 19417148
D012643 Selenium Selenium results in increased expression of HSPA1A mRNAincreases expression 19244175
D012834 Silver Silver promotes the reaction [HSF1 protein binds to HSPA1A enhancer]affects binding|increases reaction 16460681
D012834 Silver Silver promotes the reaction [HSF1 protein binds to HSPA1A promoter]affects binding|increases reaction 17244614
D012834 Silver Silver results in increased expression of HSPA1A mRNAincreases expression 17244614
D012835 Silver Nitrate Silver Nitrate promotes the reaction [HSF1 protein binds to HSPA1A enhancer]affects binding|increases reaction 16460681
D012835 Silver Nitrate Silver Nitrate promotes the reaction [HSF1 protein binds to HSPA1A promoter]affects binding|increases reaction 17244614
D012835 Silver Nitrate Silver Nitrate results in increased expression of HSPA1A mRNAincreases expression 17244614
C017947 sodium arsenite sodium arsenite results in increased expression of HSPA1A mRNAincreases expression 12016162
16966095
12760830
C017947 sodium arsenite sodium arsenite results in increased expression of HSPA1A proteinincreases expression 16729991
C017947 sodium arsenite TP53 protein promotes the reaction [sodium arsenite results in increased expression of HSPA1A mRNA]increases expression|increases reaction 16966095
C017947 sodium arsenite Quercetin inhibits the reaction [sodium arsenite results in increased expression of HSPA1A protein]decreases reaction|increases expression 14606951
C017947 sodium arsenite sodium arsenite results in increased expression of HSPA1A mRNAincreases expression 16322246
C017947 sodium arsenite chelerythrine inhibits the reaction [sodium arsenite results in increased expression of HSPA1A protein]decreases reaction|increases expression 12690470
C017947 sodium arsenite sodium arsenite inhibits the reaction [Cisplatin results in decreased expression of HSPA1A protein]decreases expression|decreases reaction 12690470
C017947 sodium arsenite sodium arsenite results in increased expression of HSPA1A mRNAincreases expression 12842450
12388181
16815819
C017947 sodium arsenite sodium arsenite results in increased expression of HSPA1A proteinincreases expression 16729991
12690470
12842450
D020058 Styrene Styrene results in increased expression of HSPA1A proteinincreases expression 16705669
D013629 Tamoxifen Tamoxifen results in increased expression of HSPA1A proteinincreases expression 12460799
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of HSPA1A mRNAincreases expression 20106945
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of HSPA1A mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of HSPA1A mRNAincreases expression 17035482
D013752 Tetracycline Tetracycline results in increased expression of HSPA1A mRNAincreases expression 17522070
D013849 Thimerosal Thimerosal results in increased expression of HSPA1A mRNAincreases expression 16870260
D013853 Thioacetamide gadolinium chloride inhibits the reaction [Thioacetamide results in increased expression of HSPA1A mRNA]decreases reaction|increases expression 12963478
D013853 Thioacetamide gadolinium chloride inhibits the reaction [Thioacetamide results in increased expression of HSPA1A protein]decreases reaction|increases expression 12963478
D013853 Thioacetamide Thioacetamide results in increased expression of HSPA1A mRNAincreases expression 12963478
D013853 Thioacetamide Thioacetamide results in increased expression of HSPA1A proteinincreases expression 12963478
C050414 tripterine tripterine results in increased expression of HSPA1A mRNAincreases expression 17010675
C005460 uranyl acetate uranyl acetate inhibits the reaction [Cisplatin results in decreased expression of HSPA1A protein]decreases expression|decreases reaction 12690470
C005460 uranyl acetate uranyl acetate results in increased expression of HSPA1A proteinincreases expression 12690470
D014639 Vanadium Vanadium results in increased expression of HSPA1A mRNAincreases expression 15159208
D001335 Vehicle Emissions Vehicle Emissions results in increased expression of HSPA1A mRNAincreases expression 19465080
C025643 vinclozolin vinclozolin affects the expression of HSPA1A mRNAaffects expression 19015723
D014810 Vitamin E Vitamin E results in increased expression of HSPA1A mRNAincreases expression 19244175
D024483 Vitamin K 3 Vitamin K 3 results in increased expression of HSPA1A mRNAincreases expression 12414654
D015032 Zinc Zinc promotes the reaction [HSF1 protein binds to HSPA1A enhancer]affects binding|increases reaction 16460681
D015032 Zinc Zinc promotes the reaction [HSF1 protein binds to HSPA1A promoter]affects binding|increases reaction 17244614
D015032 Zinc Zinc results in increased expression of HSPA1A mRNAincreases expression 17244614
16870260
D015032 Zinc Zinc results in increased expression of HSPA1A mRNAincreases expression 15159208
D015032 Zinc Zinc results in increased expression of HSPA1A proteinincreases expression 16949620
C016837 zinc chloride zinc chloride results in increased expression of HSPA1A proteinincreases expression 15734587
C016837 zinc chloride zinc chloride results in increased expression of HSPA1A mRNAincreases expression 16870260
D019287 Zinc Sulfate Zinc Sulfate affects the localization of HSPA1A proteinaffects localization 16239242
D019287 Zinc Sulfate Zinc Sulfate promotes the reaction [HSF1 protein binds to HSPA1A enhancer]affects binding|increases reaction 16460681
D019287 Zinc Sulfate Zinc Sulfate promotes the reaction [HSF1 protein binds to HSPA1A promoter]affects binding|increases reaction 17244614
D019287 Zinc Sulfate Zinc Sulfate results in increased expression of HSPA1A mRNAincreases expression 17244614
D019287 Zinc Sulfate Zinc Sulfate results in increased expression of HSPA1A proteinincreases expression 16239242
D019287 Zinc Sulfate Zinc Sulfate results in increased expression of HSPA1A proteinincreases expression 16949620
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 3.6014745880
MESH:D000014 Abnormalities, Drug-Induced Carbamazepine 9.118986270
MESH:D000014 Abnormalities, Drug-Induced Ethanol 9.1117676605 18926900
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 9.1111752688 15322242 14514962
MESH:D000138 Acidosis Ammonium Chloride 12.5118287403
MESH:D000138 Acidosis Ethanol 12.5111192467
MESH:D000138 Acidosis Zinc Sulfate 12.517265320
MESH:D000142 Acidosis, Respiratory Copper Sulfate 5.487265320
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.0017505938
MESH:D000169 Acrodermatitis Zinc 4.4716889938 17190629 17202136
MESH:D058186 Acute Kidney Injury marker/mechanism 12690470
MESH:D058186 Acute Kidney Injury Cisplatin 13.7717670903 15814532 12690470
MESH:D058186 Acute Kidney Injury Gentamicins 13.7711274264
MESH:D058186 Acute Kidney Injury Ibuprofen 13.776375363
MESH:D058186 Acute Kidney Injury Mercuric Chloride 13.7711274264
MESH:D055371 Acute Lung Injury pirinixic acid 2.2618653653
MESH:D000230 Adenocarcinoma arsenic trioxide 21.4011798837 19825857
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 21.4020127859 20464547
MESH:D000230 Adenocarcinoma Cisplatin 21.4011798837 17638652
MESH:D000230 Adenocarcinoma Doxorubicin 21.4017418594
MESH:D000230 Adenocarcinoma Estradiol 21.4011473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 21.4014692618
MESH:D000230 Adenocarcinoma Genistein 21.4011473722
MESH:D000230 Adenocarcinoma Ibuprofen 21.4010697514
MESH:D000230 Adenocarcinoma Indomethacin 21.4016537180
MESH:D000236 Adenoma Benzo(a)pyrene 10.806695378
MESH:D000236 Adenoma beta-Naphthoflavone 10.8019389873
MESH:D000236 Adenoma Diethylnitrosamine 10.8010737359 6695378
MESH:D000236 Adenoma Indomethacin 10.8011497255
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 11.9319052882 18056438 17620307 16434500 19061943 17162532
MESH:D018248 Adenoma, Liver Cell pirinixic acid 11.9316434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 11.9316835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 3.7515276417
MESH:D018246 Adrenocortical Adenoma Arsenic 10.6517306315
MESH:D018246 Adrenocortical Adenoma sodium arsenite 10.6516712894 17306315
MESH:D000382 Agricultural Workers' Diseases Lindane 3.4712661182
MESH:D000419 Albuminuria Doxorubicin 8.5021441931
MESH:D000419 Albuminuria Raloxifene 8.5017308373 17451421
MESH:D020268 Alcohol-Induced Disorders, Nervous System Ethanol 4.3715451039 15451040
MESH:D016301 Alveolar Bone Loss Indomethacin 4.4217225004
MESH:D000544 Alzheimer Disease Copper 11.4017119284 16962711 16325427 16886094 16410023 16866297
MESH:D000544 Alzheimer Disease Ibuprofen 11.4018351690
MESH:D000544 Alzheimer Disease Indomethacin 11.4015579461 17627676
MESH:D000544 Alzheimer Disease Ozone 11.4015513908
MESH:D000544 Alzheimer Disease Raloxifene 11.4015800139
MESH:D000544 Alzheimer Disease Zinc 11.4016410023 16580781 17119284 16325427
MESH:D000686 Amyloidosis Diethylstilbestrol 3.5915469931
MESH:D000690 Amyotrophic Lateral Sclerosis Copper 6.5810694572
MESH:D000690 Amyotrophic Lateral Sclerosis Tetrahydrocannabinol 6.5815204022
MESH:D000707 Anaphylaxis Ibuprofen 4.339532969
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.1311748828
MESH:D000741 Anemia, Aplastic Benzene 3.6011369114 17661222 14761424
MESH:D000743 Anemia, Hemolytic Quercetin 3.3917084956
MESH:D018798 Anemia, Iron-Deficiency Copper 4.0416614410
MESH:D000755 Anemia, Sickle Cell Zinc 4.0116916123
MESH:D000799 Angioedema Acetaminophen 2.9010982225
MESH:D000853 Anophthalmos Ethanol 3.9115513904
MESH:D000860 Anoxia Copper Sulfate 8.757265320
MESH:D000860 Anoxia Zinc Sulfate 8.757265320
MESH:D001008 Anxiety Disorders Ethanol 6.4311141031
MESH:D001008 Anxiety Disorders vinclozolin 6.4319015723
MESH:D001014 Aortic Aneurysm Indomethacin 3.9510231640
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 8.6819183758
MESH:D017544 Aortic Aneurysm, Abdominal Indomethacin 8.6810388637
MESH:D001129 Argyria Silver 5.9416531870
MESH:D020261 Arsenic Poisoning Arsenic 2.5118414634 12569548 16251483 16835338
MESH:D001161 Arteriosclerosis Cyclophosphamide 7.1615014928
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 7.1611256880
MESH:D018771 Arthralgia Indomethacin 4.222160914
MESH:D001169 Arthritis, Experimental Carrageenan 8.7117392412
MESH:D001169 Arthritis, Experimental Dexamethasone 8.7117659584
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 8.7115885639
MESH:D001172 Arthritis, Rheumatoid Indomethacin 5.6411248219
MESH:D001172 Arthritis, Rheumatoid Ozone 5.6415570426
MESH:D001172 Arthritis, Rheumatoid phenylmethylpyrazolone 5.6416390820
MESH:D001249 Asthma Ozone 3.8316373670 17854713
MESH:D001249 Asthma Zinc 3.8317085522
MESH:D001260 Ataxia Telangiectasia Quercetin 4.0415336622
MESH:D050197 Atherosclerosis Arsenic 7.5819371607 12928151
MESH:D050197 Atherosclerosis Cadmium 7.5815687053
MESH:D050197 Atherosclerosis Tetrahydrocannabinol 7.5815815632
MESH:D001321 Autistic Disorder Acetaminophen 2.2218445737
MESH:D001321 Autistic Disorder Mercury 2.2217497416
MESH:D001327 Autoimmune Diseases Mercury 7.9916634805
MESH:D001327 Autoimmune Diseases Quercetin 7.9919761891
MESH:D001477 Bartter Syndrome Indomethacin 4.0710684365
MESH:D001714 Bipolar Disorder Carbamazepine 3.5617594078 20046352
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 19.9216206674
MESH:D001778 Blood Coagulation Disorders Omeprazole 19.9219483382
MESH:D001778 Blood Coagulation Disorders pirinixic acid 19.9219483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 19.9212125929
MESH:D001778 Blood Coagulation Disorders Thioacetamide 19.9219483382
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 2.8415340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.0915746008
MESH:D001855 Bone Marrow Diseases Benzene 4.2816183116
MESH:D019046 Bone Marrow Neoplasms Cisplatin 8.9214601052
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 8.9214601052
MESH:D001862 Bone Resorption bisphenol A 3.0211985600
MESH:D001929 Brain Edema Indomethacin 4.0811481608
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 4.3917868700
MESH:D001930 Brain Injuries Progesterone 13.2115665606 15380490 15845082
MESH:D001930 Brain Injuries Raloxifene 13.2116580743
MESH:D001930 Brain Injuries Zinc 13.2117109824
MESH:D002545 Brain Ischemia Ibuprofen 11.9615837124
MESH:D002545 Brain Ischemia Indomethacin 11.9612524144
MESH:D002545 Brain Ischemia Morphine 11.9619211983
MESH:D001932 Brain Neoplasms Copper 6.4517079463
MESH:D001932 Brain Neoplasms Doxorubicin 6.4517150277
MESH:D001943 Breast Neoplasms Ascorbic Acid 20.1316443354
MESH:D001943 Breast Neoplasms Benzene 20.1317162533 11921183
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 20.1320146248 17474063
MESH:D001943 Breast Neoplasms bisphenol A 20.1317123778
MESH:D001943 Breast Neoplasms Cisplatin 20.1318382427 19526202
MESH:D001943 Breast Neoplasms Copper 20.1317079463 15986119
MESH:D001943 Breast Neoplasms Cyclophosphamide 20.1311325840 12006526 18234424 18323546 17388661 16978400 15093573 15136595 17020986
MESH:D001943 Breast Neoplasms Diethylnitrosamine 20.1317474063
MESH:D001943 Breast Neoplasms Diethylstilbestrol 20.1317129689 15324884
MESH:D001943 Breast Neoplasms Doxorubicin 20.1318695136 16826403 15939500 15692762 16264153 16595493 16096432 18234424 18628466 17369602 19526202 15994142 17983394 15668708 11325840 16115903 15993339 17426702 15634643 15567936 18382427 15136595 16322301 16935488
MESH:D001943 Breast Neoplasms Estradiol 20.1317289903 14630087 12948864 17018787 17261762 19861407 18497071 16675129
MESH:D001943 Breast Neoplasms Genistein 20.1316873071 16541309 17200150
MESH:D001943 Breast Neoplasms Indomethacin 20.1317401462
MESH:D001943 Breast Neoplasms Lindane 20.1314688026
MESH:D001943 Breast Neoplasms Progesterone 20.1317614352 15562024 16175315
MESH:D001943 Breast Neoplasms Quercetin 20.1318628248
MESH:D001943 Breast Neoplasms Raloxifene 20.1315775269 15572757 17049068 16912660 17952589 15758505 17440819 17893378 17242785 16837676 17261762 17595753
MESH:D001943 Breast Neoplasms Styrene 20.1315986119
MESH:D001943 Breast Neoplasms Tamoxifen 20.1317049068 18351453 19288272 16202921 19487384 19084267 21138602 20544844 19410462 19115204 18997820 18815881 20065188 19221464 19059307 17893378 19103187 18855134 17261762 18629630 21152245 19011961 17440819 19142967 19200415 20135344 16818667 15565566 19244106 19189210 18984771 15668708 16273361 19189212 20005174 11161223 20390343 19155303 20859285 18821012 16873071 19066611 18425577 17242785 19289846
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 20.1320435547
MESH:D001943 Breast Neoplasms Vanadium 20.1315565634
MESH:D016535 Bronchial Hyperreactivity Ozone 2.9115516495 19059883 18417511 14754758 18315731 16777450 17626835
MESH:D002051 Burkitt Lymphoma arsenic trioxide 3.4511589617
MESH:D002056 Burns Ethanol 13.9116374292
MESH:D002056 Burns Indomethacin 13.9110459503
MESH:D002056 Burns Silver 13.9116531870
MESH:D002100 Cachexia Ibuprofen 15.7815141370
MESH:D002100 Cachexia Indomethacin 15.7815141370 16537180 11239499 15625704
MESH:D002100 Cachexia Ozone 15.7816183385
MESH:D002105 Cadmium Poisoning Quercetin 4.5916962696
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 3.5316111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 6.9218705752 15673190 3786805 15721981 16192424 15700767 10355542 16227642 16097048 16124888 16011737 16050911
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 6.9216050911
MESH:D002276 Carcinoid Tumor Doxorubicin 3.8616051944
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.0316835633
MESH:D002280 Carcinoma, Basal Cell Arsenic 2.9715504454 17687452
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 3.5919066611
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 43.1116705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 43.113084413
MESH:D006528 Carcinoma, Hepatocellular Arsenic 43.1116507464 17306315
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 43.1114691202 11135700 16217749 15553829 15073043
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 43.1118788625
MESH:D006528 Carcinoma, Hepatocellular Cisplatin 43.1117982673
MESH:D006528 Carcinoma, Hepatocellular Cyclophosphamide 43.1119701751
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 43.1118393292 20512989 19171122 18506893 16502159 19519916 16328049 17162532 17173139 19335982 17138121 20084675 17978847 20007298 19208518 19822196 19701751 20524982 19919837 18665156 17055752 11831363 20214788 10737359 16935385 20432363 3084413 19383236 19539802 19394651 16569478 18978308 17761372 16779866 10672840 16830150 18210153 16807293 19052882 19107877 16288022 18785209 20514400 18691550 18971187 21159647 18788625 16681979 16878318 19418558 20727157 18494052 20101231 20935162 16698587 18056438 3581430 17428255 16540662
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 43.1115948411 16924424
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 43.1117876044 18059187 16023760 16234567
MESH:D006528 Carcinoma, Hepatocellular Estradiol 43.1116924424
MESH:D006528 Carcinoma, Hepatocellular Ethanol 43.1118788625 15763234 15289165
MESH:D006528 Carcinoma, Hepatocellular Genistein 43.1116924424
MESH:D006528 Carcinoma, Hepatocellular Indomethacin 43.1116391822
MESH:D006528 Carcinoma, Hepatocellular Quercetin 43.1119519916 12508355
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 43.1115276417 17306315 16507464
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 43.1116924424
MESH:D006528 Carcinoma, Hepatocellular Thioacetamide 43.1117997003
MESH:D006528 Carcinoma, Hepatocellular Vanadium 43.1116830150 16878318
MESH:D002278 Carcinoma in Situ bisphenol A 4.0517123778
MESH:D018827 Carcinoma, Lewis Lung Cyclophosphamide 8.4516152834
MESH:D018827 Carcinoma, Lewis Lung Indomethacin 8.4511053908
MESH:D018276 Carcinoma, Medullary Indomethacin 4.4214736730 18791128 11352223
MESH:D002289 Carcinoma, Non-Small-Cell Lung Carboplatin 4.6616685392
MESH:D002289 Carcinoma, Non-Small-Cell Lung Cisplatin 4.6612023789 16685392
MESH:D021441 Carcinoma, Pancreatic Ductal marker/mechanism 17234771
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.0417234771
MESH:D002291 Carcinoma, Papillary arsenic trioxide 3.9219014326
MESH:D002292 Carcinoma, Renal Cell Cyclophosphamide 7.7316201981
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 7.7316201981 1485588
MESH:D002292 Carcinoma, Renal Cell Indomethacin 7.7317341418
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.2812490120
MESH:D002294 Carcinoma, Squamous Cell Arsenic 15.7818922899 15504454 17687452
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 15.7820419170
MESH:D002294 Carcinoma, Squamous Cell Cisplatin 15.7817066447 18337622 6189445
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 15.786189445
MESH:D002294 Carcinoma, Squamous Cell Indomethacin 15.7815482327 12636206
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 15.7818572023
MESH:D002294 Carcinoma, Squamous Cell Zinc 15.7816543248
MESH:D002295 Carcinoma, Transitional Cell Arsenic 11.1218640142
MESH:D002295 Carcinoma, Transitional Cell Raloxifene 11.1217572228
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 11.1217572228
MESH:D006332 Cardiomegaly Copper 11.3117327471
MESH:D006332 Cardiomegaly Ethanol 11.3119332462
MESH:D006332 Cardiomegaly Quercetin 11.3119794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 11.3118670907 16120746 18850075
MESH:D009202 Cardiomyopathies Doxorubicin 2.8516242529 18627295 17924179 17131338 16455267 16364871 17928571 15505089 16612575 16731534 17007740 17351982 16952015 16651473 16278810 16109756 17974986 17329180 15792986 16269455 17382496 15476868 15811867 17308081 17519947
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 4.7017334414 16243910
MESH:D002311 Cardiomyopathy, Dilated Mercury 4.7010334427
MESH:D002318 Cardiovascular Diseases Arsenic 15.2715738583 17938729 19152805
MESH:D002318 Cardiovascular Diseases Genistein 15.2716332659
MESH:D002318 Cardiovascular Diseases Hydrogen Peroxide 15.2716936243
MESH:D002318 Cardiovascular Diseases Raloxifene 15.2715775269
MESH:D002318 Cardiovascular Diseases Zinc 15.2716936243
MESH:D002340 Carotid Artery Diseases Arsenic 3.4918022660 16973168
MESH:D002375 Catalepsy Tetrahydrocannabinol 4.8010318961
MESH:D002386 Cataract Acetaminophen 1.9510977129
MESH:D002471 Cell Transformation, Neoplastic Cadmium 21.0817332340
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 21.0812371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 21.0817174075 7505956 21159647 2727394
MESH:D002471 Cell Transformation, Neoplastic Estradiol 21.0818566989
MESH:D002471 Cell Transformation, Neoplastic Methylnitronitrosoguanidine 21.082727394
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 21.0820056578 19524636
MESH:D002471 Cell Transformation, Neoplastic Vanadium 21.0817174075
MESH:D002543 Cerebral Hemorrhage phenylmethylpyrazolone 4.9219095969
MESH:D002637 Chest Pain Omeprazole 4.1615447763
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 11.4219052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 11.4216835633
MESH:D018281 Cholangiocarcinoma Thioacetamide 11.4218291259
MESH:D002761 Cholangitis 1-Naphthylisothiocyanate 5.2512912871
MESH:D002764 Cholecystitis Indomethacin 4.2211181007
MESH:D002779 Cholestasis 1-Naphthylisothiocyanate 13.1915500046 18590720 18164287 12927374 19486331 16629650 15913567 7624871
MESH:D002779 Cholestasis Cyclosporine 13.1919486331
MESH:D002779 Cholestasis Ethinyl Estradiol 13.1917681005 11677210 16919318 17333356 16105132 17110522 15861022
MESH:D002779 Cholestasis pirinixic acid 13.1919176532
MESH:D002780 Cholestasis, Intrahepatic 1-Naphthylisothiocyanate 4.9010220858 19407337
MESH:D002971 Cleft Lip Ethanol 3.0015513904
MESH:D002972 Cleft Palate Ethanol 7.1915513904
MESH:D002972 Cleft Palate geranylgeranylacetone 7.1915340226
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 7.198697196 15668235 15340226 12621046 16354765
MESH:D003072 Cognition Disorders Raloxifene 3.7115800139
MESH:D003092 Colitis polaprezinc 7.3617036391
MESH:D003092 Colitis Selenium 7.3617936198
MESH:D003110 Colonic Neoplasms arsenite 10.1915037631
MESH:D003110 Colonic Neoplasms Dexamethasone 10.1915824018
MESH:D003110 Colonic Neoplasms Genistein 10.1917182828
MESH:D003110 Colonic Neoplasms Indomethacin 10.1911260862 15786552 15936596 15963497 15637740 15625704
MESH:D003110 Colonic Neoplasms Quercetin 10.1919440933 11134977 17148506 15741050 19056647 17191121 16640504
MESH:D003110 Colonic Neoplasms Vanadium 10.1918155637
MESH:D015179 Colorectal Neoplasms arsenic trioxide 4.7220501625
MESH:D015179 Colorectal Neoplasms Cisplatin 4.7215273666
MESH:D015179 Colorectal Neoplasms Doxorubicin 4.7218259882 18802399
MESH:D015179 Colorectal Neoplasms Indomethacin 4.7212606626 18059344 17054584 11197048
MESH:D015179 Colorectal Neoplasms Quercetin 4.7218852136 18095365
MESH:D003139 Common Cold Ascorbic Acid 4.5317323712
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.2517141729 14669216
MESH:D023903 Coronary Restenosis arsenic trioxide 3.2912609071
MESH:D018352 Coronavirus Infections Indomethacin 4.7717302372
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 10.7610525206
MESH:D019465 Craniofacial Abnormalities Benzene 10.7615643154
MESH:D019465 Craniofacial Abnormalities Carbamazepine 10.769014606
MESH:D019465 Craniofacial Abnormalities Dexamethasone 10.7617728286
MESH:D019465 Craniofacial Abnormalities Ethanol 10.7611198716 19302082 15451040 15451039 11873399 10194807 15513904
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 10.7620055451 10048152 15322242
MESH:D019465 Craniofacial Abnormalities Vitamin E 10.7619769572
MESH:D019465 Craniofacial Abnormalities Zinc 10.7619302082
MESH:D003456 Cryptorchidism Diethylstilbestrol 8.4112952375 16002989
MESH:D003456 Cryptorchidism vinclozolin 8.4114966744
MESH:D003490 Cyanosis 2,4-dinitrotoluene 3.1018551238
MESH:D003556 Cystitis Cyclophosphamide 4.0417010015 15643279 18483878 18433785 18710439 18372110 10700343 16614059 12161096 18093676 16651033 12913760 17979934 15276878 18295254 10498854 11948286 16413132 16989017 12388444
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.2215213294
MESH:D003711 Demyelinating Diseases Tamoxifen 3.4519031437
MESH:D003865 Depressive Disorder, Major Raloxifene 3.3517474826
MESH:D003872 Dermatitis Benzene 3.8615902427
MESH:D017449 Dermatitis, Allergic Contact Dexamethasone 6.8412438553
MESH:D017449 Dermatitis, Allergic Contact Mercury 6.8416823706
MESH:D017449 Dermatitis, Allergic Contact Thimerosal 6.8415932584 16958921
MESH:D003876 Dermatitis, Atopic pirinixic acid 1.8918249437
MESH:D002658 Developmental Disabilities Thimerosal 4.1515764492
MESH:D003920 Diabetes Mellitus Zinc 3.4016479319
MESH:D003921 Diabetes Mellitus, Experimental Cyclophosphamide 6.0410990075 11751995 15331540
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 6.0419496084
MESH:D003922 Diabetes Mellitus, Type 1 Cyclophosphamide 2.8418772604
MESH:D003924 Diabetes Mellitus, Type 2 Ascorbic Acid 7.2916506275
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 7.2920387270
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 7.2916647724
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 7.2917107852
MESH:D003928 Diabetic Nephropathies Estradiol 10.3419279558
MESH:D003928 Diabetic Nephropathies Raloxifene 10.3417308373 17451421 15920148
MESH:D003928 Diabetic Nephropathies Tamoxifen 10.3419279558
MESH:D003929 Diabetic Neuropathies Progesterone 3.5817187935
MESH:D003967 Diarrhea Dexamethasone 8.477237001
MESH:D003967 Diarrhea Indomethacin 8.477237001 7907874
MESH:D003967 Diarrhea Morphine 8.472540324
OMIM:607208 DRAVET SYNDROME Carbamazepine 4.5311748493
MESH:D004342 Drug Hypersensitivity marker/mechanism 16538175
MESH:D004342 Drug Hypersensitivity Carbamazepine 3.7616538176 16538175 15057820 20216337
MESH:D056486 Drug-Induced Liver Injury 1-Naphthylisothiocyanate 46.6417522070 7624871 18289764 20133375
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 46.6418551238 21346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 46.6412540782 11421492 11743745 14725611 14550746 16081117 11739529 16781746 16485898 11834606 19370779 16227642 10663392 12958197 17562736 19085960 16393943 12705907 2444490 14986274 19923254 15619225 12392966 19416960 19420014 17906064 11529661 18071297 12153990 15968718 12594235 16177239 19164858 11461765 18713872 17522070 10774834 10915739 11287661 16109766 19739265
MESH:D056486 Drug-Induced Liver Injury Carbamazepine 46.6417465707
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 46.647440962 3732212 4309450 7179309 16227642 11566570 10915739 10092053 16177239 6884620 21278145 15998439 2869522 6623471 15968718 15027814 19085960 19336974 9327722 3786805 17522070 7120509
MESH:D056486 Drug-Induced Liver Injury Chlorodiphenyl (54% Chlorine) 46.6417851650
MESH:D056486 Drug-Induced Liver Injury Chloroform 46.642862719 7440962 3732212 17522070 7120509 6623471 6884620 3104120
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 46.6419107877
MESH:D056486 Drug-Induced Liver Injury Diquat 46.6418445702 18164269
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 46.6417416283
MESH:D056486 Drug-Induced Liver Injury Ethanol 46.6411566570
MESH:D056486 Drug-Induced Liver Injury gadolinium chloride 46.6412963478
MESH:D056486 Drug-Induced Liver Injury pyrazole 46.6412499123
MESH:D056486 Drug-Induced Liver Injury Selenium 46.6415131321
MESH:D056486 Drug-Induced Liver Injury Silver 46.6416531870
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 46.6420420201
MESH:D056486 Drug-Induced Liver Injury Tetracycline 46.6417522070
MESH:D056486 Drug-Induced Liver Injury Thioacetamide 46.6412963478
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.1519426721
MESH:D004362 Drug Toxicity Carbamazepine 22.4920216337
MESH:D004362 Drug Toxicity Cisplatin 22.4912231392 12649298 15033597 19839026
MESH:D004362 Drug Toxicity Doxorubicin 22.4918602426
MESH:D004362 Drug Toxicity Gentamicins 22.4911033412 15033597
MESH:D004362 Drug Toxicity phenylmethylpyrazolone 22.4912231392 12649298
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 22.4911462148
MESH:D004374 Ductus Arteriosus, Patent Ibuprofen 10.1418450898 18446180 16133044
MESH:D004374 Ductus Arteriosus, Patent Indomethacin 10.1416133044 18446180 17190690 18043480 12774134 16326151
MESH:D004381 Duodenal Ulcer Indomethacin 6.5917151854 16699067 17045617 11595431 17329845 11595415 11535926 17351913 11991626 10671773 17202747
MESH:D004381 Duodenal Ulcer Omeprazole 6.5917151854 16613094 15991576 21218061
MESH:C538011 Eales disease Ascorbic Acid 9.929068938
MESH:C538011 Eales disease Vitamin E 9.929068938
MESH:D004485 Eczema Dexamethasone 3.5712438553
MESH:D004487 Edema Carrageenan 16.3312787963 12798668 18841975 8985016 16100529 17259670 12083418 18449507 18621150 10653021 15860553
MESH:D004487 Edema Dexamethasone 16.3319703484
MESH:D004487 Edema Indomethacin 16.3310653021 7907874 8273558 16100529 19703484 7990266 8985016
MESH:D004487 Edema pirinixic acid 16.3312083418
MESH:D004487 Edema Raloxifene 16.3315860553
MESH:D004487 Edema Tetrachlorodibenzodioxin 16.3312711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 2.9515322242 16714409 18230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Carbamazepine 19.4417654737
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 19.4412538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 19.4417692515
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Raloxifene 19.4415845917
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 19.4419031437
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 8.8016402032
MESH:D004714 Endometrial Hyperplasia Genistein 8.8016402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 16.1215700306 16804899
MESH:D016889 Endometrial Neoplasms Doxorubicin 16.1217359293
MESH:D016889 Endometrial Neoplasms Estradiol 16.1219148513 11473722 18566989
MESH:D016889 Endometrial Neoplasms Genistein 16.1211473722
MESH:D016889 Endometrial Neoplasms Tamoxifen 16.1217893378 19155303 16202921 20544844
MESH:D004715 Endometriosis Ibuprofen 15.1015652904
MESH:D004715 Endometriosis Indomethacin 15.1015652904
MESH:D004715 Endometriosis Progesterone 15.1016134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 15.1010568697 9294722
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 4.2118037988
MESH:D019446 Endotoxemia Ibuprofen 12.5011545620
MESH:D019446 Endotoxemia Indomethacin 12.5018509659
MESH:D019446 Endotoxemia phenylmethylpyrazolone 12.5012954792
MESH:D004751 Enteritis Indomethacin 3.8017763956 16328016 10567023
MESH:D020345 Enterocolitis, Necrotizing Indomethacin 4.0717980183
MESH:D004802 Eosinophilia Cyclophosphamide 6.2511006010
MESH:D004802 Eosinophilia Indomethacin 6.2511298111
MESH:D004816 Epidermal Necrolysis, Toxic Carbamazepine 4.3619915237 20485159 16538176 16415921 18855540
MESH:D004831 Epilepsies, Myoclonic Carbamazepine 4.3017275665
MESH:D004828 Epilepsies, Partial Carbamazepine 4.0416628512 17116037 15008574
MESH:D004827 Epilepsy Carbamazepine 5.707988514 19620853 18234410 19700373 17178248 9014606 17465707 821787 19439326 20417680
MESH:D004827 Epilepsy Tetrahydrocannabinol 5.70821787
MESH:D004832 Epilepsy, Absence Naloxone 4.446254150
MESH:D017029 Epilepsy, Complex Partial Carbamazepine 4.447750514
MESH:D004830 Epilepsy, Tonic-Clonic Carbamazepine 4.2015276670 3659116
MESH:D004916 Erythromelalgia Carbamazepine 4.7919549232
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.1716302075
MESH:D004938 Esophageal Neoplasms arsenic trioxide 12.6112903497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 12.6116530937
MESH:D004938 Esophageal Neoplasms Cisplatin 12.6116481741 15464296 17638652 15173087 16785472
MESH:D004938 Esophageal Neoplasms Ethanol 12.6116704527
MESH:D004938 Esophageal Neoplasms Indomethacin 12.6111005569
MESH:D004938 Esophageal Neoplasms Zinc 12.6116543248
MESH:D005076 Exanthema Carbamazepine 4.5420485159
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.2711564622
MESH:D005218 Fat Necrosis Thioacetamide 4.7716456712
MESH:D005234 Fatty Liver arsenic trioxide 47.9415073043
MESH:D005234 Fatty Liver arsenite 47.9418296743
MESH:D005234 Fatty Liver Carbon Tetrachloride 47.9412631006 61145 12795759 16045604 15959796 19224547 16239168 17595544
MESH:D005234 Fatty Liver Cyclosporine 47.9419224547
MESH:D005234 Fatty Liver Diethylnitrosamine 47.9420387270 21071580
MESH:D005234 Fatty Liver Ethanol 47.9418620774 19236843 16409862
MESH:D005234 Fatty Liver Ethinyl Estradiol 47.9415345470
MESH:D005234 Fatty Liver phenylmethylpyrazolone 47.9412795759
MESH:D005234 Fatty Liver pirinixic acid 47.9419236843 20131406
MESH:D005234 Fatty Liver Raloxifene 47.9417473493
MESH:D005234 Fatty Liver Tamoxifen 47.9414986274 19224547
MESH:D005234 Fatty Liver Tetracycline 47.9419224547 16917069
MESH:D005235 Fatty Liver, Alcoholic Ethanol 4.7117920746
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 6.0216002989 16611131 15751030 16513791 16534752
MESH:D052776 Female Urogenital Diseases Tamoxifen 6.0216709447
MESH:D005310 Fetal Alcohol Syndrome Ethanol 4.3616946407 15513904 15451040 10194807
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 2.5511858732
MESH:D005334 Fever Ibuprofen 6.8116997862
MESH:D005334 Fever Indomethacin 6.8117627676 11852909 10431976
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 3.5914745880
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 8.3619069698
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 8.3619069698
MESH:D005354 Fibrosarcoma Carrageenan 9.5010962813
MESH:D005354 Fibrosarcoma Indomethacin 9.5010962813
MESH:D005355 Fibrosis arsenite 22.9218296743
MESH:D005355 Fibrosis Carbon Tetrachloride 22.9218705752
MESH:D005355 Fibrosis Cyclosporine 22.9212639820 12168785
MESH:D005355 Fibrosis Indomethacin 22.9217994277
MESH:D005355 Fibrosis Quercetin 22.9219474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 22.9220067830
MESH:D005499 Folliculitis Indomethacin 4.2211298111
MESH:D005534 Foot Diseases Arsenic 4.616392382
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.3716904648
MESH:D005756 Gastritis Acetaminophen 26.1016983495
MESH:D005756 Gastritis Diquat 26.1015046732
MESH:D005756 Gastritis Ethanol 26.1015046732
MESH:D005756 Gastritis Indomethacin 26.1015046732
MESH:D005756 Gastritis Zinc 26.1017241300
MESH:D005767 Gastrointestinal Diseases geranylgeranylacetone 5.9316324314
MESH:D030342 Genetic Diseases, Inborn vinclozolin 4.0016973722
MESH:D005832 Genital Diseases, Male vinclozolin 4.3516417039
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 9.7216452187
MESH:D005833 Genital Neoplasms, Female sodium arsenite 9.7216452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.298708960
MESH:D005909 Glioblastoma Doxorubicin 11.4017150277
MESH:D005909 Glioblastoma Genistein 11.4016598420
MESH:D005909 Glioblastoma Indomethacin 11.4012870263
MESH:D005909 Glioblastoma Quercetin 11.4019804834
MESH:D005910 Glioma Indomethacin 4.6818371953 16487511
MESH:D005910 Glioma Quercetin 4.6817643826
MESH:D018316 Gliosarcoma Cyclophosphamide 4.5811389073
MESH:D005923 Glomerulosclerosis, Focal Segmental Indomethacin 3.5011849393
MESH:D006030 Glycosuria, Renal Mercuric Chloride 4.982918855
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 3.6410696789
MESH:D006073 Gout Indomethacin 4.4211248219
MESH:D006086 Graft vs Host Disease Cyclophosphamide 4.1215172196 16376943 11014644
MESH:D006130 Growth Disorders Zinc 3.2917217573
MESH:D006258 Head and Neck Neoplasms Cisplatin 9.0415102660 15464296
MESH:D006258 Head and Neck Neoplasms Doxorubicin 9.0415692506
MESH:D006258 Head and Neck Neoplasms Indomethacin 9.0415482327
MESH:D034381 Hearing Loss Cisplatin 12.1119898482
MESH:D034381 Hearing Loss Gentamicins 12.1118024279 17868369 15968427 19130971
MESH:D034381 Hearing Loss Styrene 12.1117420221
MESH:D006319 Hearing Loss, Sensorineural Cisplatin 3.6215464296
MESH:D006330 Heart Defects, Congenital Ascorbic Acid 11.1016080930
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 11.1020471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 11.1011294989 10048152
MESH:D006330 Heart Defects, Congenital Vitamin E 11.1016080930
MESH:D006331 Heart Diseases Doxorubicin 5.4816879835 16707910 16244372 17888722 17875725 16244371 18006777 16330681 16495754 18674790 14766674 12587719 16144979
MESH:D006331 Heart Diseases Raloxifene 5.4811110106
MESH:D006333 Heart Failure Doxorubicin 11.4817481944
MESH:D006333 Heart Failure pirinixic acid 11.4820558911
MESH:D006333 Heart Failure Selenium 11.4817162251
MESH:D006333 Heart Failure Zinc 11.4817162251
MESH:D006335 Heart Injuries Zinc 4.8217074742
MESH:D018882 Heat Stress Disorders therapeutic 16627676
MESH:D016481 Helicobacter Infections Zinc 3.6617241300
MESH:D006394 Hemangiosarcoma Doxorubicin 3.0615692506
MESH:D006402 Hematologic Diseases Benzene 3.7816183116
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 3.4915720958
MESH:D006467 Hemophilia A Cyclophosphamide 4.3711918545
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.4811000095
MESH:D006501 Hepatic Encephalopathy Indomethacin 8.1015633222
MESH:D006501 Hepatic Encephalopathy Thioacetamide 8.1018665440 17276928 15929193
MESH:D006504 Hepatic Veno-Occlusive Disease Cyclophosphamide 4.5814986274
MESH:D006505 Hepatitis 1-Naphthylisothiocyanate 10.7718590720
MESH:D006505 Hepatitis Carbon Tetrachloride 10.7719110552 19900420
MESH:D006505 Hepatitis Thioacetamide 10.7716456712
MESH:D019698 Hepatitis C, Chronic Indomethacin 3.7915135802
MESH:D006521 Hepatitis, Chronic Copper 4.3317338147
MESH:D006527 Hepatolenticular Degeneration Copper 13.4119888908 16607473 17276780 17109627 17182432
MESH:D006527 Hepatolenticular Degeneration Zinc 13.4117276780
MESH:D006527 Hepatolenticular Degeneration Zinc Sulfate 13.4117063115
MESH:D006529 Hepatomegaly 1,4-bis(2-(3,5-dichloropyridyloxy))benzene 9.3516109766
MESH:D006529 Hepatomegaly pirinixic acid 9.3519772884 16221962 18467677 19176532
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 9.3515340226 12621046 16120746
MESH:D006548 Hernia, Diaphragmatic Ascorbic Acid 7.0416863852 16490937
MESH:D006548 Hernia, Diaphragmatic Dexamethasone 7.047520565
MESH:D006548 Hernia, Diaphragmatic Vitamin E 7.0416863852 16490937
MESH:D006558 Herpes Genitalis Estradiol 4.0815709030
MESH:D006689 Hodgkin Disease Cisplatin 10.9716200630 16170182
MESH:D006689 Hodgkin Disease Cyclophosphamide 10.9717606976 16135485
MESH:D006689 Hodgkin Disease Doxorubicin 10.9717606976 15147373 18501091
MESH:D006689 Hodgkin Disease sodium arsenite 10.9712676792
MESH:D019584 Hot Flashes Estradiol 6.9217088409
MESH:D019584 Hot Flashes Vitamin E 6.9214716179
MESH:D006869 Hydronephrosis geranylgeranylacetone 10.2515340226
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 10.2515340226 18606429 8697196 16354765 16959395
MESH:D006930 Hyperalgesia Acetaminophen 8.6816870215
MESH:D006930 Hyperalgesia Ethanol 8.6818783367
MESH:D006930 Hyperalgesia Indomethacin 8.6812727271
MESH:D034321 Hyperamylasemia Indomethacin 4.7717883296
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 3.6016899240
MESH:D053565 Hypercalciuria Gentamicins 4.7717652376
MESH:D006940 Hyperemia Indomethacin 4.0712524144
MESH:D006943 Hyperglycemia pirinixic acid 6.4820558911
MESH:D006943 Hyperglycemia Quercetin 6.4811834736 18262572
MESH:D020138 Hyperhomocysteinemia Carbamazepine 3.9210459572
MESH:D017488 Hyperkeratosis, Epidermolytic Arsenic 3.6217050553
MESH:D006949 Hyperlipidemias Indomethacin 3.3017546600
MESH:D006965 Hyperplasia Carbamazepine 8.2818773962
MESH:D006965 Hyperplasia Diethylstilbestrol 8.2812960047 14722030
MESH:D006973 Hypertension Arsenic 17.6116076760 9931084 11953799
MESH:D006973 Hypertension Benzene 17.6117940673
MESH:D006973 Hypertension Cyclosporine 17.6110903974
MESH:D006973 Hypertension Dexamethasone 17.6117042910
MESH:D006973 Hypertension Quercetin 17.6118356687
MESH:D006973 Hypertension Raloxifene 17.6117577099 15787275
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 17.6118850075 18670907
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 8.8115338365
MESH:D006975 Hypertension, Portal polaprezinc 8.8116984587
MESH:D006976 Hypertension, Pulmonary Copper Sulfate 4.367265320
MESH:D006984 Hypertrophy Ibuprofen 4.1216672835
MESH:D017379 Hypertrophy, Left Ventricular phenylmethylpyrazolone 4.5715824197
MESH:D006987 Hypesthesia Arsenic 4.6116093927
MESH:D007021 Hypospadias Diethylstilbestrol 8.2216002989
MESH:D007021 Hypospadias Ethinyl Estradiol 8.2216945680 16569931
MESH:D007022 Hypotension Zinc Sulfate 3.627265320
MESH:D007035 Hypothermia Tetrahydrocannabinol 5.0210318961
MESH:D007077 Ileal Diseases Indomethacin 4.0818306037 10574470
MESH:D007079 Ileitis Indomethacin 4.4210651667 10647630 16133968
MESH:D007154 Immune System Diseases Cyclophosphamide 10.6016076520
MESH:D007154 Immune System Diseases Silver 10.6017996693
MESH:D007235 Infant, Premature, Diseases Ibuprofen 11.0516133044
MESH:D007235 Infant, Premature, Diseases Indomethacin 11.0516133044
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 3.4915869954
MESH:D007246 Infertility Diethylstilbestrol 3.4615036965
MESH:D007247 Infertility, Female Ethinyl Estradiol 2.5912013081
MESH:D007248 Infertility, Male Coumestrol 21.2916892005
MESH:D007248 Infertility, Male Cyclophosphamide 21.297193160 16517039
MESH:D007248 Infertility, Male Diquat 21.294850670
MESH:D007248 Infertility, Male Ethinyl Estradiol 21.2917937319
MESH:D007248 Infertility, Male Methoxychlor 21.2911955947 16467254
MESH:D007248 Infertility, Male sodium arsenite 21.2912646999 15346721
MESH:D007248 Infertility, Male vinclozolin 21.2916467254
MESH:D007249 Inflammation Carrageenan 21.4916100529 12428691 7907874 8985016 12787963 12798668 19934399 18295198 10653021
MESH:D007249 Inflammation Dexamethasone 21.498960868 11099482
MESH:D007249 Inflammation Diethylnitrosamine 21.4918785209
MESH:D007249 Inflammation Ibuprofen 21.493291741
MESH:D007249 Inflammation Indomethacin 21.4912568917 3291741 7812673
MESH:D007249 Inflammation Progesterone 21.4915869954
MESH:D007249 Inflammation Silver 21.4917996693
MESH:D007249 Inflammation Tamoxifen 21.4919457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 21.4912200463 12878042
MESH:D015212 Inflammatory Bowel Diseases polaprezinc 4.6216949620
MESH:D007251 Influenza, Human Quercetin 13.1816624496
MESH:D007251 Influenza, Human Selenium 13.1816624496
MESH:D007251 Influenza, Human Vitamin E 13.1816624496
MESH:D007333 Insulin Resistance bisphenol A 8.3516393666
MESH:D007333 Insulin Resistance Estradiol 8.3516393666 16627594
MESH:D007333 Insulin Resistance pirinixic acid 8.3516306350
MESH:D007410 Intestinal Diseases Indomethacin 3.4218236018 15831440 17994277 11713966 15610444 17329856 11686837 11855677 10210152
MESH:D002532 Intracranial Aneurysm phenylmethylpyrazolone 4.4619381132
MESH:D019586 Intracranial Hypertension Indomethacin 4.4215241188
MESH:D007511 Ischemia phenylmethylpyrazolone 8.3216301206
MESH:D007511 Ischemia Zinc 8.3216584753
MESH:D007569 Jaw Abnormalities Ethanol 7.2915513904
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 7.2916580747
MESH:D007579 Jejunal Diseases Indomethacin 4.0810574470 16133968 18306037
MESH:D007627 Keloid Quercetin 4.0417086741
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 3.4915604871
MESH:D007642 Keratosis Arsenic 4.0612749816 16930632
MESH:D007673 Kidney Cortex Necrosis Cisplatin 10.1815464296
MESH:D007673 Kidney Cortex Necrosis Gentamicins 10.1818842672
MESH:D007674 Kidney Diseases Acetaminophen 52.0712587719 15629191
MESH:D007674 Kidney Diseases Cadmium 52.0716962696 16226777 16322080
MESH:D007674 Kidney Diseases Cadmium Chloride 52.0716962696
MESH:D007674 Kidney Diseases Cisplatin 52.0712231392 18289764 19839026 15190930 12649298
MESH:D007674 Kidney Diseases Cyclosporine 52.0710903974 8314463 18776723
MESH:D007674 Kidney Diseases Doxorubicin 52.0715699352 16775033 15369732
MESH:D007674 Kidney Diseases Estradiol 52.0715618244
MESH:D007674 Kidney Diseases Gentamicins 52.0719349640 18289764 17934191
MESH:D007674 Kidney Diseases Indomethacin 52.0717190690
MESH:D007674 Kidney Diseases Mercury 52.0717934191
MESH:D007674 Kidney Diseases phenylmethylpyrazolone 52.0718085390
MESH:D007674 Kidney Diseases Quercetin 52.0716962696
MESH:D007674 Kidney Diseases sodium arsenite 52.0720008137
MESH:D007674 Kidney Diseases Vitamin E 52.0712488133
MESH:D007674 Kidney Diseases Zinc 52.0716960431
MESH:D007676 Kidney Failure, Chronic Copper 22.3016518626
MESH:D007676 Kidney Failure, Chronic Doxorubicin 22.3016707910
MESH:D007676 Kidney Failure, Chronic Hydrogen Peroxide 22.3016518626
MESH:D007676 Kidney Failure, Chronic Selenium 22.3016518626
MESH:D007676 Kidney Failure, Chronic Zinc 22.3016518626
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 15.0616705839
MESH:D007680 Kidney Neoplasms Cyclosporine 15.0612371664
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 15.0615003126 14681315 16762066
MESH:D007680 Kidney Neoplasms Estradiol 15.0615610895
MESH:D007680 Kidney Neoplasms Tamoxifen 15.0618625569
MESH:D007683 Kidney Tubular Necrosis, Acute Cisplatin 8.8711231351
MESH:D007683 Kidney Tubular Necrosis, Acute Gentamicins 8.8711231351
MESH:D007859 Learning Disorders Copper 11.0117134702
MESH:D007859 Learning Disorders Diethylstilbestrol 11.0117184923
MESH:D007859 Learning Disorders Ethanol 11.0115451040
MESH:D007889 Leiomyoma Raloxifene 3.6216973256
MESH:D016773 Leishmaniasis, Cutaneous Gentamicins 13.4610219319
MESH:D016773 Leishmaniasis, Cutaneous Indomethacin 13.4610320625 12228301 11703811
MESH:D016773 Leishmaniasis, Cutaneous Omeprazole 13.4619248655
MESH:D016773 Leishmaniasis, Cutaneous Zinc Sulfate 13.4615237267
MESH:D007938 Leukemia arsenic trioxide 13.6315070760
MESH:D007938 Leukemia Benzene 13.6318335105 15935818 14694614 17119257
MESH:D007938 Leukemia Cyclophosphamide 13.6310602166
MESH:D007938 Leukemia Genistein 13.6318980019 17468513
MESH:D007938 Leukemia Quercetin 13.6317468513
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 4.2116085563
MESH:D015451 Leukemia, Lymphocytic, Chronic, B-Cell Cyclophosphamide 3.0017296974 17802794 18587576 17008537 17658394 18172266
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 2.9517077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 3.3816972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 9.8514633726
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Cyclophosphamide 9.8510373061
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Indomethacin 9.8510785260 15631656 16572323
MESH:D007951 Leukemia, Myeloid arsenic trioxide 6.8819077051
MESH:D007951 Leukemia, Myeloid Benzene 6.8817506065
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 4.6016968895 16467208 20471514 19850784 17050201
MESH:D015470 Leukemia, Myeloid, Acute Benzene 4.6019478238
MESH:D015470 Leukemia, Myeloid, Acute Indomethacin 4.6018360721
MESH:D015473 Leukemia, Promyelocytic, Acute Arsenic 5.5017339181
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 5.5011468182 16331271 17712046 11161223 17107899 15336539 19642359 17217047 16823087 12018890 16891316 16330433 15213294 15622746 12712474 15748426 17649720 17869043 19075265 19225113 9834237 16966277 16112521 12679006 19035177
MESH:D015458 Leukemia, T-Cell arsenic trioxide 3.4616882451
MESH:D007964 Leukocytosis Indomethacin 4.4216537180
MESH:D007969 Leukomalacia, Periventricular Indomethacin 4.7717980183
MESH:D007970 Leukopenia Cyclophosphamide 4.0410052129 11830472
MESH:D007984 Leydig Cell Tumor vinclozolin 3.8016417039
MESH:D017880 Limb Deformities, Congenital Ethanol 3.0917676605
MESH:D008064 Lipidoses Tamoxifen 2.4417567588 15342952
MESH:D008101 Liver Abscess, Amebic Indomethacin 4.7711479899
MESH:D008103 Liver Cirrhosis arsenite 10.7618296743
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 10.7621278145 11408273 11903743 16943688 16239168 16221502 17334410 17174718 17157831
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 10.7620032147 19638242 18522880 18407596 18665156
MESH:D008103 Liver Cirrhosis Ethanol 10.7615289165
MESH:D008104 Liver Cirrhosis, Alcoholic Ethanol 4.1618295389
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 22.5112632514 17525996 18054572 16192424 15818738 18481824 17805973 12958196 12389079 15052691 17698563 17565644 15925388 17721639 18472332 13678700 18006644 15876570 14620537 12741479 14716496 18205269 15673190 14716833 15931870 15996030 12649538 18395095 18277467 18339082 17481882 17631135 17823541 11481614 15370692 20821823 14512876 18418968 18210741 17900296 17708605 16116963 16638106 12609069 16015684 10355542 16248980 15362042 12445418 15057751 17869086 12586293 18472094 15959796 14748882 18187930 12666154 17640975 15730626 16011737 16136751 15123356 15338365 18166357 17761835 15893842 18412020 18279442 12546737 16033810 17714472 18705752 18395914 15650968 18376398 17944888 12898905 12667390 18251166 18156304 17557913 18420326 18429990 18263696 16027843 12632512 17922224 12445421 14724832 18317297 16097048 17976157 17766677
MESH:D008106 Liver Cirrhosis, Experimental Dexamethasone 22.5116718785
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 22.5116439617 16595196
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 22.5114716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Ethanol 22.5118166357
MESH:D008106 Liver Cirrhosis, Experimental gadolinium chloride 22.5112666154
MESH:D008106 Liver Cirrhosis, Experimental Genistein 22.5117823541
MESH:D008106 Liver Cirrhosis, Experimental Indomethacin 22.5118194892
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 22.5115474484
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 22.5112741479
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 22.5118564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 22.5112878042
MESH:D008106 Liver Cirrhosis, Experimental Thioacetamide 22.5111481614 16343077 12175628 15316131 14739098 15288472 16489207 17629604 12085344 15078482 12531686 11682029 15362042 18295389 16511523 17292413 18606216 15474484 18615449 11172339 15288473 18031379 18395095 18458672 12891558 15716488 17127702 18032466 10677585 18380797 16098781 15095483 18416461 16248980 15075984 16126171 16097051 15158331 15334695 17355460 12557150 17050028 15465738 12679928 18263696
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 22.5116169303
MESH:D008107 Liver Diseases marker/mechanism 19784758
MESH:D008107 Liver Diseases 1-Naphthylisothiocyanate 13.6317184895
MESH:D008107 Liver Diseases Acetaminophen 13.6316611625 12969438 12587719 19460945 16610002 19014921 11587558 19784758
MESH:D008107 Liver Diseases Arsenic 13.6311134558
MESH:D008107 Liver Diseases Carbon Tetrachloride 13.6316964402 16246199 17285989 15830285 15720792
MESH:D008107 Liver Diseases Diethylnitrosamine 13.6317034775
MESH:D008107 Liver Diseases Lindane 13.631715830
MESH:D008107 Liver Diseases Thioacetamide 13.6318374380 15158337 16337175
MESH:D008108 Liver Diseases, Alcoholic Ethanol 3.7417207112 17347304
MESH:D017093 Liver Failure Carbon Tetrachloride 3.2515123358
MESH:D017114 Liver Failure, Acute Acetaminophen 11.4516871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 11.4514706259 16899240
MESH:D017114 Liver Failure, Acute Thioacetamide 11.4515633222 15313186 17276928 12479984
MESH:D008113 Liver Neoplasms Arsenic 33.9416368122
MESH:D008113 Liver Neoplasms arsenic trioxide 33.9414682389
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 33.9420195826 21137059
MESH:D008113 Liver Neoplasms beta-Naphthoflavone 33.9419389873 21295105
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 33.9419294768
MESH:D008113 Liver Neoplasms Copper 33.9420302851
MESH:D008113 Liver Neoplasms Diethylnitrosamine 33.9419090486 12112319 19850985 19690152 10737359 20452335 19427195 20101389 19833225 19426721 21167192 20137499 19073162 19812893 2422723 19254457 19642983 15175105 20118626 19499222 21278145 12771043 19551842 18644402 2862719 18977376 20583210 19638242 20434301 18648771 9163691 18754104 18978307 19294768 19256749 16942905 21047994 19255062 21071580 19996281 20501860 20405173 20492335 15885732
MESH:D008113 Liver Neoplasms Diethylstilbestrol 33.9415890375 16712894
MESH:D008113 Liver Neoplasms pirinixic acid 33.9416377806 20007298 15890375
MESH:D008113 Liver Neoplasms Quercetin 33.9418980244
MESH:D008113 Liver Neoplasms sodium arsenite 33.9415276417 16712894
MESH:D008113 Liver Neoplasms Tamoxifen 33.9416684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 33.9416984957
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 33.0120377131
MESH:D008114 Liver Neoplasms, Experimental Ascorbic Acid 33.0118544905
MESH:D008114 Liver Neoplasms, Experimental Benzene 33.0112562636
MESH:D008114 Liver Neoplasms, Experimental beta-Naphthoflavone 33.0118164116
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 33.0112014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 33.012563599 18079962 18282651 18544905 9362446 18775883 18253720 19009564 21159647 19539802 16842330 16267830 19126423 19519916 18093689 19004024 18164116 17174075 17942915 3124819 18308698 17854601
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 33.0116842330 17085340
MESH:D008114 Liver Neoplasms, Experimental kojic acid 33.0118544905
MESH:D008114 Liver Neoplasms, Experimental Quercetin 33.0119519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 33.0112151625
MESH:D008114 Liver Neoplasms, Experimental Vanadium 33.0117174075
MESH:D008133 Long QT Syndrome arsenic trioxide 2.6015213294
MESH:D008171 Lung Diseases Ascorbic Acid 11.9216863852
MESH:D008171 Lung Diseases Ozone 11.9219066396 8266340
MESH:D008171 Lung Diseases sodium arsenite 11.9219095001
MESH:D008171 Lung Diseases Vitamin E 11.9216863852
MESH:D017563 Lung Diseases, Interstitial Benzene 3.8614698565
MESH:D055370 Lung Injury Asbestos, Crocidolite 6.2517365036
MESH:D055370 Lung Injury Ozone 6.2520417186
MESH:D008175 Lung Neoplasms Arsenic 35.0817306315 19168569 17976673
MESH:D008175 Lung Neoplasms arsenic trioxide 35.0811798837 19825857
MESH:D008175 Lung Neoplasms arsenite 35.0816809336
MESH:D008175 Lung Neoplasms Ascorbic Acid 35.0816401635
MESH:D008175 Lung Neoplasms Benzene 35.0812562636
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 35.0820869020 18569708 18520028 18816296 6695378 20464547 20064080 20135361 17053015
MESH:D008175 Lung Neoplasms Cisplatin 35.086189445 11798837 17225452
MESH:D008175 Lung Neoplasms Dexamethasone 35.0815824018 11195469
MESH:D008175 Lung Neoplasms Diethylnitrosamine 35.086695378 20970405 20512841 21163286
MESH:D008175 Lung Neoplasms Doxorubicin 35.0817418594 6189445
MESH:D008175 Lung Neoplasms Indomethacin 35.0811053908 11497255 16537180
MESH:D008175 Lung Neoplasms Ozone 35.088597069 7614698
MESH:D008175 Lung Neoplasms Quercetin 35.0816280456
MESH:D008175 Lung Neoplasms sodium arsenite 35.0817306315 15276417 16712894 19931552 17077188
MESH:D008175 Lung Neoplasms Styrene 35.0812562636
MESH:D008175 Lung Neoplasms Tamoxifen 35.0818625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 35.0811884234 19555203
MESH:D008175 Lung Neoplasms Vehicle Emissions 35.089255578
MESH:D008175 Lung Neoplasms Vitamin E 35.0811062179
MESH:D008180 Lupus Erythematosus, Systemic Carbamazepine 3.2116628512
MESH:D008181 Lupus Nephritis Diethylstilbestrol 4.2115166399
MESH:D008223 Lymphoma Benzene 12.0117119257 17584886
MESH:D008223 Lymphoma Cyclophosphamide 12.0112854902
MESH:D008223 Lymphoma Diethylstilbestrol 12.0115700306
MESH:D008223 Lymphoma Doxorubicin 12.0116098063
MESH:D016393 Lymphoma, B-Cell Cyclophosphamide 3.7316675587
MESH:D008228 Lymphoma, Non-Hodgkin Cyclophosphamide 6.3611911406
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 6.3617654614
MESH:D016399 Lymphoma, T-Cell Doxorubicin 3.6515621674
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 4.5616002989
MESH:D015674 Mammary Neoplasms, Animal Benzene 11.6412562636
MESH:D015674 Mammary Neoplasms, Animal Styrene 11.6412562636
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 11.6419428831
MESH:D008325 Mammary Neoplasms, Experimental Benzene 25.4211921183
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 25.4215458769
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 25.4211807958 11408345 17203775 16891317
MESH:D008325 Mammary Neoplasms, Experimental Genistein 25.4214578162 12929590
MESH:D008325 Mammary Neoplasms, Experimental Ibuprofen 25.4210697514
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 25.4211408345 17203775
MESH:D008325 Mammary Neoplasms, Experimental Selenium 25.4215318939
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 25.4211731420 19196722 14580682 19196723 16827153
MESH:D008325 Mammary Neoplasms, Experimental Zinc 25.4212773700
MESH:D020149 Manganese Poisoning Estradiol 9.5019453300
MESH:D020149 Manganese Poisoning Tamoxifen 9.5019453300
MESH:D008545 Melanoma Carboplatin 8.8212040289 11712820 16342250 16225601
MESH:D008545 Melanoma Cisplatin 8.8217761969 12374674 16432458 11135225 18505091 18176117 16809738 12883367 17023156 18332650 16248763 12393984 15577323
MESH:D008545 Melanoma Doxorubicin 8.8216827129
MESH:D008545 Melanoma sodium arsenite 8.8216487513 19082730
MESH:D008545 Melanoma Tamoxifen 8.8212393984 19393235
MESH:D008545 Melanoma Vitamin K 3 8.8219082730
MESH:D018328 Melanoma, Amelanotic Cisplatin 8.4215990972
MESH:D018328 Melanoma, Amelanotic Tamoxifen 8.4215990972
MESH:D008546 Melanoma, Experimental Acetaminophen 7.8119513568
MESH:D008546 Melanoma, Experimental Cyclophosphamide 7.8116388313
MESH:D008569 Memory Disorders Ethanol 3.3115451040 18411066
MESH:D007706 Menkes Kinky Hair Syndrome Copper 4.9517109627 17268249
MESH:D008607 Mental Retardation Carbamazepine 3.319014606
MESH:D008654 Mesothelioma Asbestos, Crocidolite 10.4716966607 18303189 16166281
MESH:D008654 Mesothelioma Cisplatin 10.4717638057
MESH:D008654 Mesothelioma Doxorubicin 10.4717638057
MESH:D008654 Mesothelioma Selenium 10.4715107826
MESH:D008659 Metabolic Diseases phenylmethylpyrazolone 4.6216301206
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 3.8416801185
MESH:D008679 Metaplasia Ozone 4.1610496685
MESH:D053842 Microsatellite Instability Methylnitronitrosoguanidine 4.9517671175
MESH:D008881 Migraine Disorders Indomethacin 2.9711903285
MESH:D028361 Mitochondrial Diseases Doxorubicin 3.6415792986
MESH:D018200 Mixed Tumor, Mullerian Raloxifene 4.6015863610
MESH:D009041 Motion Sickness Dextroamphetamine 4.571613127
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 6.1316381670
MESH:D009062 Mouth Neoplasms Indomethacin 6.1312636206
MESH:D052016 Mucositis Doxorubicin 3.8617415656
MESH:D009101 Multiple Myeloma arsenic trioxide 15.0919549372 19417148 15949261 14977855 11468182
MESH:D009101 Multiple Myeloma Benzene 15.0917119195
MESH:D009101 Multiple Myeloma Dexamethasone 15.0915867202 15744524 16118317
MESH:D009101 Multiple Myeloma Raloxifene 15.0916497877
MESH:D009101 Multiple Myeloma S-(dimethylarsino)-glutathione 15.0919417148
MESH:D009135 Muscular Diseases pirinixic acid 2.6016239165
MESH:D009137 Muscular Dystrophy, Animal Gentamicins 5.3218694830
MESH:D009182 Mycosis Fungoides arsenic trioxide 3.7218349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 5.4616105982 16882451
MESH:D009190 Myelodysplastic Syndromes Dexamethasone 5.469809623
MESH:D009203 Myocardial Infarction Doxorubicin 9.3619429709 15857846
MESH:D009203 Myocardial Infarction Genistein 9.3617141266
MESH:D009203 Myocardial Infarction pirinixic acid 9.3619151258
MESH:D009203 Myocardial Infarction Quercetin 9.3619595682
MESH:D017202 Myocardial Ischemia Arsenic 6.4115371236
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 6.4112213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 14.0816810080
MESH:D015428 Myocardial Reperfusion Injury Genistein 14.0817141266
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 14.0816411023
MESH:D015428 Myocardial Reperfusion Injury Quercetin 14.0819207477
MESH:D009224 Myotonia Congenita Carbamazepine 4.5420399394
MESH:D009232 Myxoma Raloxifene 4.6016343187
MESH:D009336 Necrosis 2,4-dinitrotoluene 2.9318551238
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.0716624393
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 9.513581430 9029167
MESH:D009362 Neoplasm Metastasis Doxorubicin 9.5118259882
MESH:D009362 Neoplasm Metastasis Indomethacin 9.5111239499 11053908 16537180
MESH:D009362 Neoplasm Metastasis Tamoxifen 9.5119393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.1119410462
MESH:D009369 Neoplasms 4-phenylbutyric acid 24.9019116145
MESH:D009369 Neoplasms Benzo(a)pyrene 24.9011141357
MESH:D009369 Neoplasms Carboplatin 24.9017925555 18854779
MESH:D009369 Neoplasms Cisplatin 24.9016773208
MESH:D009369 Neoplasms Cyclophosphamide 24.9018854779
MESH:D009369 Neoplasms Diethylstilbestrol 24.9015313581
MESH:D009369 Neoplasms Lindane 24.9012807735 16818664
MESH:D009369 Neoplasms pirinixic acid 24.9017405874
MESH:D009369 Neoplasms Quercetin 24.9015185748
MESH:D009369 Neoplasms sodium arsenite 24.9011559025
MESH:D009374 Neoplasms, Experimental Indomethacin 6.2815625704 10663608
MESH:D009374 Neoplasms, Experimental sodium arsenite 6.2820056578
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.0619200415 19189210 19196722
MESH:D009389 Neovascularization, Pathologic arsenite 11.7815738583
MESH:D009389 Neovascularization, Pathologic Copper 11.7817308104
MESH:D009389 Neovascularization, Pathologic Estradiol 11.7817289903
MESH:D009395 Nephritis, Interstitial Cisplatin 12.4215464296
MESH:D009395 Nephritis, Interstitial Ibuprofen 12.426375363
MESH:D009395 Nephritis, Interstitial Tetracycline 12.429884423
MESH:D009401 Nephrosis Doxorubicin 3.8516899518 16636307
MESH:D009402 Nephrosis, Lipoid Cyclosporine 3.4917954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 6.5918481113 19348381
MESH:D009404 Nephrotic Syndrome Doxorubicin 6.5916889571 15640375
MESH:D009410 Nerve Degeneration Ibuprofen 3.6410961664
MESH:D009421 Nervous System Malformations bisphenol A 26.9116427766 11399458
MESH:D009421 Nervous System Malformations Carbamazepine 26.9116990009
MESH:D009421 Nervous System Malformations Diethylstilbestrol 26.9111399458
MESH:D009421 Nervous System Malformations Estradiol 26.9111399458 16427766
MESH:D009421 Nervous System Malformations Genistein 26.9116427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 26.9114600291
MESH:D009436 Neural Tube Defects Arsenic 15.5916620997
MESH:D009436 Neural Tube Defects arsenic trioxide 15.5910525206
MESH:D009436 Neural Tube Defects Benzene 15.5915643154
MESH:D009436 Neural Tube Defects sodium arsenite 15.5912854658
MESH:D009436 Neural Tube Defects Tetrahydrocannabinol 15.5919040278
MESH:D009447 Neuroblastoma Cisplatin 8.138761367
MESH:D009447 Neuroblastoma Cyclophosphamide 8.1316115947 8761367 15176712
MESH:D009447 Neuroblastoma Doxorubicin 8.1315555623
MESH:D019636 Neurodegenerative Diseases Acetaminophen 9.5018514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 9.5020387270
MESH:D019636 Neurodegenerative Diseases Indomethacin 9.5012349958
MESH:D017599 Neuroectodermal Tumors Carboplatin 13.8812837982
MESH:D017599 Neuroectodermal Tumors Cisplatin 13.888761367
MESH:D017599 Neuroectodermal Tumors Cyclophosphamide 13.8812837982 8761367
MESH:D020078 Neurogenic Inflammation Arsenic 7.7917056641
MESH:D020078 Neurogenic Inflammation Quercetin 7.7917929310
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.1720387270
MESH:D009503 Neutropenia Cyclophosphamide 3.478291058
MESH:D009765 Obesity Ascorbic Acid 3.5817217161
MESH:D009765 Obesity pirinixic acid 3.5820558911
MESH:D007752 Obstetric Labor, Premature Indomethacin 4.226374098
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 6.4116049721 12819281
MESH:D009784 Occupational Diseases Benzene 6.4115913788 15612468 15727169 17479406 15935809 15576619 16737584 17178637 17119257
MESH:D009845 Oligospermia Cyclophosphamide 3.7916517039
MESH:D010003 Osteoarthritis Ibuprofen 5.887009135
MESH:D010003 Osteoarthritis Indomethacin 5.887009135
MESH:D010018 Osteomalacia Carbamazepine 4.5417016548
MESH:D010024 Osteoporosis Genistein 5.1519401787
MESH:D010024 Osteoporosis Raloxifene 5.1517882678 15775268 19059307
MESH:D015663 Osteoporosis, Postmenopausal Genistein 11.8816169203
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 11.8819495926
MESH:D015663 Osteoporosis, Postmenopausal Raloxifene 11.8815579764 17823083 15758505 17893378
MESH:D012516 Osteosarcoma Doxorubicin 3.3315930896
MESH:D010049 Ovarian Diseases bisphenol A 4.0511985600
MESH:D010051 Ovarian Neoplasms Arsenic 22.9917306315
MESH:D010051 Ovarian Neoplasms arsenic trioxide 22.9912452020 19769630 16624393
MESH:D010051 Ovarian Neoplasms Benzene 22.9912562636
MESH:D010051 Ovarian Neoplasms Cisplatin 22.9919769630 17225452 15464296 6897625
MESH:D010051 Ovarian Neoplasms Estradiol 22.9919401270
MESH:D010051 Ovarian Neoplasms Genistein 22.9919005980
MESH:D010051 Ovarian Neoplasms Progesterone 22.9917393432 16525653
MESH:D010051 Ovarian Neoplasms Quercetin 22.9919005980
MESH:D010051 Ovarian Neoplasms sodium arsenite 22.9915276417 17306315
MESH:D010146 Pain Acetaminophen 16.4516870215
MESH:D010146 Pain Carbamazepine 16.4515215642
MESH:D010146 Pain Cyclophosphamide 16.4512161096 18093676
MESH:D010146 Pain Ibuprofen 16.453291741
MESH:D010146 Pain Indomethacin 16.4517627676 13679232 17440234 3291741
MESH:D010146 Pain Morphine 16.4516273134 15215642 18699797 15275824 6776300 20225289
MESH:D010149 Pain, Postoperative Ibuprofen 8.3416678543
MESH:D010149 Pain, Postoperative Indomethacin 8.3418702446 12538197
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 17.7615580305
MESH:D010190 Pancreatic Neoplasms Cisplatin 17.7619003803
MESH:D010190 Pancreatic Neoplasms Cyclophosphamide 17.7611332152
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 17.7616540662
MESH:D010190 Pancreatic Neoplasms Ethanol 17.7612384795
MESH:D010190 Pancreatic Neoplasms Ibuprofen 17.7612384795
MESH:D010190 Pancreatic Neoplasms Quercetin 17.7616965848
MESH:D010195 Pancreatitis Indomethacin 9.5315028970 17883296
MESH:D010195 Pancreatitis Methomyl 9.5316258382 15767733
MESH:D010195 Pancreatitis phenylmethylpyrazolone 9.5320035747
MESH:D016584 Panic Disorder Ethinyl Estradiol 2.8111578682
MESH:D010212 Papilloma Hydrogen Peroxide 3.1912065085
MESH:D010235 Paraganglioma arsenic trioxide 3.2919927285
MESH:D010257 Paraneoplastic Syndromes Indomethacin 4.7716537180
MESH:D010267 Parapsoriasis Carbamazepine 4.7816538176
MESH:D010300 Parkinson Disease therapeutic 15585408
MESH:D020734 Parkinsonian Disorders Indomethacin 3.3012349958
OMIM:167400 PAROXYSMAL EXTREME PAIN DISORDER Carbamazepine 4.9917679678 17145499
MESH:D051302 Paroxysmal Hemicrania Indomethacin 4.7711903285
MESH:D010382 Peliosis Hepatis 1-Naphthylisothiocyanate 10.6420133375
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 10.6412520081
MESH:D010391 Pemphigoid, Bullous Tetracycline 4.4811026799
MESH:D010437 Peptic Ulcer Indomethacin 4.2211148446
MESH:D010518 Periodontitis Indomethacin 3.9717225004
MESH:D010523 Peripheral Nervous System Diseases Arsenic 7.1116093927
MESH:D010523 Peripheral Nervous System Diseases Cisplatin 7.1115464296
MESH:D016491 Peripheral Vascular Diseases Arsenic 10.0015371236 6392382 16905509
MESH:D016491 Peripheral Vascular Diseases Cadmium 10.0015687053
MESH:D010538 Peritonitis Ozone 3.2316369182
MESH:D003557 Phyllodes Tumor Doxorubicin 4.2117983394
MESH:D010900 Pituitary Diseases Diethylstilbestrol 4.2214722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 3.7615687265 16977796
MESH:D010954 Plasmacytoma Selenium 3.9415087411
MESH:D010995 Pleural Diseases Asbestos, Crocidolite 3.9810923243
MESH:D010997 Pleural Neoplasms Cisplatin 10.7917638057
MESH:D010997 Pleural Neoplasms Doxorubicin 10.7917638057
MESH:D010998 Pleurisy Carrageenan 5.8019934399
MESH:D011014 Pneumonia Ozone 3.4718007984 18929643 18381685
MESH:D011041 Poisoning Methomyl 4.5811800311
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 2.6718163543
MESH:D011230 Precancerous Conditions Cyclosporine 10.6312371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 10.632563599
MESH:D011230 Precancerous Conditions Quercetin 10.6319056647
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Cyclophosphamide 5.7521297632
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Dexamethasone 5.7521297632
MESH:D011225 Pre-Eclampsia Zinc 3.4117114810
MESH:D011248 Pregnancy Complications Carbamazepine 4.249014606
MESH:D047928 Premature Birth Indomethacin 4.2117000239
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 20.7710548101
MESH:D011297 Prenatal Exposure Delayed Effects Carbamazepine 20.779014606
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 20.7717184923
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 20.7711118676 11222880 11896295 11399792
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 20.7718042343 18220299 19015723
MESH:D017096 Prion Diseases Tetracycline 4.4810903871
MESH:D011469 Prostatic Diseases vinclozolin 4.0018220299
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 7.7220887781
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 7.7220887781
MESH:D011471 Prostatic Neoplasms marker/mechanism 15764345
MESH:D011471 Prostatic Neoplasms Arsenic 11.0916140617
MESH:D011471 Prostatic Neoplasms arsenic trioxide 11.0919131511
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 11.0917292933
MESH:D011471 Prostatic Neoplasms bisphenol A 11.0916740699
MESH:D011471 Prostatic Neoplasms Cadmium 11.0917075824
MESH:D011471 Prostatic Neoplasms Copper 11.0917079463 17308104
MESH:D011471 Prostatic Neoplasms Coumestrol 11.0916921512
MESH:D011471 Prostatic Neoplasms Cyclophosphamide 11.0917136230
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 11.0915846301 17136230 15046698
MESH:D011471 Prostatic Neoplasms Doxorubicin 11.0915749863 15897917 16888761 16729912 16868541 18437689
MESH:D011471 Prostatic Neoplasms Estradiol 11.0916740699
MESH:D011471 Prostatic Neoplasms Genistein 11.0915256057 16925846 15378649
MESH:D011471 Prostatic Neoplasms Ibuprofen 11.0917409433
MESH:D011471 Prostatic Neoplasms Lindane 11.0914688026 12661182
MESH:D011471 Prostatic Neoplasms Quercetin 11.0917292933 14715546
MESH:D011471 Prostatic Neoplasms Raloxifene 11.0916220300 15731164 16536755
MESH:D011471 Prostatic Neoplasms sodium arsenite 11.0916039940
MESH:D011471 Prostatic Neoplasms Tamoxifen 11.0915067354
MESH:D011471 Prostatic Neoplasms Vitamin E 11.0915084515
MESH:D011471 Prostatic Neoplasms Zinc 11.0916700911 12429649 16606632 16517595
MESH:D011472 Prostatitis vinclozolin 4.0018629315
MESH:D011507 Proteinuria Arsenic 15.0321343184
MESH:D011507 Proteinuria Gentamicins 15.0315033597
MESH:D011507 Proteinuria Ibuprofen 15.036375363
MESH:D011507 Proteinuria Indomethacin 15.0311849393
MESH:D011537 Pruritus Ethinyl Estradiol 6.9615861022 16919318
MESH:D011537 Pruritus Naloxone 6.9615861022
MESH:D019310 Pseudolymphoma Carbamazepine 4.659591791 12752131
MESH:D011565 Psoriasis Cyclosporine 1.8016882103
MESH:D011629 Puberty, Precocious bisphenol A 3.8510548101
MESH:D011657 Pulmonary Eosinophilia Ascorbic Acid 4.3814606601
MESH:D011658 Pulmonary Fibrosis Asbestos, Crocidolite 4.4517975199 17365031 15814490 17322281
MESH:D011658 Pulmonary Fibrosis Cyclophosphamide 4.4516636934
MESH:D011693 Purpura Raloxifene 4.6015770314
MESH:D000608 Renal Aminoacidurias Mercuric Chloride 5.152918855
MESH:D051437 Renal Insufficiency Cisplatin 12.0615464296
MESH:D051437 Renal Insufficiency Doxorubicin 12.0617922066
MESH:D051437 Renal Insufficiency Gentamicins 12.0617132701 15728788
MESH:D015427 Reperfusion Injury Morphine 7.9319211983
MESH:D015427 Reperfusion Injury phenylmethylpyrazolone 7.9314654979 15086910 16753835 15629865 16041266 15948865
MESH:D015427 Reperfusion Injury pirinixic acid 7.9319058328
MESH:D012128 Respiratory Distress Syndrome, Adult Dexamethasone 3.1618379247 11700416
MESH:D012135 Respiratory Sounds Vehicle Emissions 4.3218950799
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 2.9418990726
MESH:D012162 Retinal Degeneration Zinc 3.3816584753
MESH:D012173 Retinitis Gentamicins 5.3218644591
MESH:D012174 Retinitis Pigmentosa Ascorbic Acid 2.9616849425
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.4218045962
MESH:D012509 Sarcoma Doxorubicin 3.1616767912 17203757 15625365 17710206 15675481 18313854
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 12.1616646077
MESH:D012512 Sarcoma, Ewing's Cisplatin 12.1614601052
MESH:D012512 Sarcoma, Ewing's Doxorubicin 12.1614601052 16326096
MESH:D012514 Sarcoma, Kaposi Doxorubicin 3.8617846226
MESH:D012554 Schistosomiasis japonica Quercetin 4.5916862918
MESH:D012559 Schizophrenia Copper 2.9216842975
MESH:D012595 Scleroderma, Systemic Cyclophosphamide 3.9516636934
MESH:D012640 Seizures 2,4-dinitrotoluene 17.5718551238
MESH:D012640 Seizures Carbamazepine 17.579046859 15946322 16876388 16180713 9844417 16938433 19414003
MESH:D012640 Seizures Dizocilpine Maleate 17.5717157343 11218047 12660363
MESH:D012640 Seizures Ethanol 17.579754883
MESH:D012640 Seizures Kainic Acid 17.5714637104 19186208 16336964 18657176 1641125 17827730 10686065 15686955 19414003
MESH:D012640 Seizures Lindane 17.5712842176 7539098 15475178
MESH:D012640 Seizures Methomyl 17.5711218047 12660363
MESH:D012871 Skin Diseases Arsenic 5.9019834688 16759981 16702368 6392382 17453740 17548696 18709164 16353154 17050553 17938729 15952646
MESH:D012871 Skin Diseases Ascorbic Acid 5.9018709164
MESH:D012871 Skin Diseases Vitamin E 5.9018709164
MESH:D012878 Skin Neoplasms Arsenic 18.7517029826 15504454 17976673 17050553 16251483 19538983
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 18.7519755658 10029692
MESH:D012878 Skin Neoplasms Doxorubicin 18.7515692506
MESH:D012878 Skin Neoplasms Hydrogen Peroxide 18.7512065085
MESH:D012878 Skin Neoplasms sodium arsenite 18.7518572023 19524636
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 18.758532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 18.7516192470
MESH:D012893 Sleep Disorders Carbamazepine 8.4119414003
MESH:D012893 Sleep Disorders Kainic Acid 8.4119414003
MESH:D055752 Small Cell Lung Carcinoma Cisplatin 4.3915464296
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 3.6515625365 16767912 17203757
MESH:D013088 Spermatocele Diethylstilbestrol 14.6816002989 16709447
MESH:D013088 Spermatocele Ethinyl Estradiol 14.6816709447
MESH:D013088 Spermatocele Tamoxifen 14.6816709447
OMIM:102530 SPERMATOGENIC FAILURE 6 Cyclophosphamide 4.5816517039
MESH:D013119 Spinal Cord Injuries Progesterone 7.7915862959 16503802
MESH:D013119 Spinal Cord Injuries Tamoxifen 7.7919457130
MESH:D016135 Spinal Dysraphism sodium arsenite 3.0312854658
MESH:D013262 Stevens-Johnson Syndrome Carbamazepine 4.3016538176 18855540 19915237 16415921 19694795 15057820 20485159
MESH:D013272 Stomach Diseases Dexamethasone 11.8115472012
MESH:D013272 Stomach Diseases Indomethacin 11.8116280098 17207306 10192188 10215738 17638125 15472012 16113693 15038085 18545984 10486359 18209964 17160473 16184426
MESH:D013272 Stomach Diseases Omeprazole 11.8118545984
MESH:D013274 Stomach Neoplasms arsenic trioxide 7.6117007042
MESH:D013274 Stomach Neoplasms Benzene 7.6112562636
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 7.612093021 20155912
MESH:D013274 Stomach Neoplasms Cisplatin 7.6118396642 17522103 15958060
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 7.6118456281
MESH:D013274 Stomach Neoplasms Ethanol 7.6118456281
MESH:D013274 Stomach Neoplasms Indomethacin 7.6115609394
MESH:D013276 Stomach Ulcer Ascorbic Acid 21.1718726076
MESH:D013276 Stomach Ulcer Dexamethasone 21.1715138204
MESH:D013276 Stomach Ulcer Ethanol 21.179211565 16755016 17189318 11906479 9562338 17918041
MESH:D013276 Stomach Ulcer geranylgeranylacetone 21.1717189318
MESH:D013276 Stomach Ulcer Indomethacin 21.1717977527 12787963 16755016 12500499 16150113 17657623 17627676 16252198 18431645 11595415 1323529 11145282 15104355 18193104 17918041 11729361 15138204 18299717 12077510 18209962 18543354 18237397 16397915 11523592 11906479 18087811 10750652 15255614 17135157 14567935 16631530 11595431 10423059 16169175 10878458 17654042 16934674 18181030 17895592 12498302 12467913 18726076
MESH:D013276 Stomach Ulcer Omeprazole 21.1711906479 10750652 18237397 16755016 17977527 15991576
MESH:D013276 Stomach Ulcer polaprezinc 21.1716984587
MESH:D020521 Stroke Ascorbic Acid 10.0216403987 16517955
MESH:D020521 Stroke Raloxifene 10.0216837676
MESH:D020521 Stroke Vitamin E 10.0216517955
MESH:D019966 Substance-Related Disorders bisphenol A 3.0716684133 16045194
MESH:D013375 Substance Withdrawal Syndrome Ethanol 3.429754883
MESH:D015173 Supratentorial Neoplasms Carboplatin 9.3912837982
MESH:D015173 Supratentorial Neoplasms Cyclophosphamide 9.3912837982
MESH:D013733 Testicular Diseases pyrazole 3.896499806
MESH:D013736 Testicular Neoplasms Cisplatin 3.7617225452 15464296
MESH:D013921 Thrombocytopenia 1-Naphthylisothiocyanate 3.9220133375
MESH:D019851 Thrombophilia Ethinyl Estradiol 2.7511994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.3515669648
MESH:D013953 Thymus Neoplasms Benzene 4.0210850423
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 2.9512697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 11.0019014326
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 11.007505956
MESH:D013964 Thyroid Neoplasms Doxorubicin 11.0016010429 17909728
MESH:D013964 Thyroid Neoplasms Indomethacin 11.0018791128 14736730 11352223
MESH:D013978 Tibial Fractures Estradiol 10.5719048282
MESH:D013978 Tibial Fractures Raloxifene 10.5719048282
MESH:D014062 Tongue Neoplasms Zinc 3.5716543248
MESH:D016171 Torsades de Pointes arsenic trioxide 3.0415213294
MESH:D014456 Ulcer Indomethacin 9.6510574470 17380554
MESH:D014456 Ulcer polaprezinc 9.6511043455
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 38.0116049721
MESH:D001749 Urinary Bladder Neoplasms Arsenic 38.0117976673 19429237 11144890 18640142 19322015 17306315 15987713
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 38.0112973940 20435036 11780464 12845720
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 38.0117053015
MESH:D001749 Urinary Bladder Neoplasms Cisplatin 38.0112973940 17225452 15464296
MESH:D001749 Urinary Bladder Neoplasms Cyclophosphamide 38.0114692829
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 38.0116712894 16452187 17306315
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 38.0117653716
MESH:D001749 Urinary Bladder Neoplasms Quercetin 38.0116720314
MESH:D001749 Urinary Bladder Neoplasms Raloxifene 38.0117572228
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 38.0116712894 16452187 17306315 11723127
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 38.0116712894 17572228 8653321
MESH:D001749 Urinary Bladder Neoplasms Vehicle Emissions 38.0111144890
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 3.3810091137
MESH:D014581 Urticaria Acetaminophen 2.1210982225
MESH:D002583 Uterine Cervical Neoplasms Cisplatin 11.1616803524
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 11.1616175088
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 11.1611813266
MESH:D014591 Uterine Diseases bisphenol A 10.6714652134
MESH:D014591 Uterine Diseases Diethylstilbestrol 10.6714652134
MESH:D014594 Uterine Neoplasms Benzene 10.9812562636
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 10.9815809267 16690809
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 10.9814692618
MESH:D014605 Uveitis Cyclosporine 8.631336536
MESH:D014605 Uveitis Dexamethasone 8.631336536
MESH:D014625 Vaginal Neoplasms Cisplatin 8.0615577323
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 8.0616002989 16513791
MESH:D014652 Vascular Diseases Arsenic 8.7617056641
MESH:D014652 Vascular Diseases sodium arsenite 8.7617056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 3.6412125929
MESH:D020301 Vasospasm, Intracranial Ibuprofen 4.2619057314
MESH:D054556 Venous Thromboembolism Raloxifene 4.2616837676
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 2.6914671159 15869587
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 3.3217334414 17638931 17678736 16364871
MESH:D015837 Vestibular Diseases Gentamicins 4.6218776599
MESH:D014839 Vomiting Cisplatin 8.3911897121
MESH:D014839 Vomiting Indomethacin 8.3911897121
MESH:D014846 Vulvar Neoplasms Raloxifene 4.6016343187
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.3015886252
MESH:D014985 Xerophthalmia Cyclosporine 3.4917120751
Pathway ID Pathway Name
KEGG:04612 Antigen processing and presentation
KEGG:04144 Endocytosis
KEGG:04010 MAPK signaling pathway
KEGG:05162 Measles
REACT:21257 Metabolism of RNA
KEGG:05020 Prion diseases
KEGG:04141 Protein processing in endoplasmic reticulum
KEGG:03040 Spliceosome
KEGG:05145 Toxoplasmosis
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA29498
    • No data
    Releated disease ID Related disease Name
    PA443936Drug Hypersensitivity
    PA444059Epidermal Necrolysis, Toxic
    PA445738Stevens-Johnson Syndrome
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    Releated drug ID Related drug Name
    PA448785carbamazepine
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB03431 - Adenosine-5'-Diphosphate
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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