AutismKB 2.0

Annotation Detail for HSPA1L


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Basic Information Top
Gene Symbol:HSPA1L ( HSP70-1L,HSP70-HOM,HSP70T,hum70t )
Gene Full Name: heat shock 70kDa protein 1-like
Band: 6p21.33
Quick LinksEntrez ID:3305; OMIM: 140559; Uniprot ID:HS71L_HUMAN; ENSEMBL ID: ENSG00000204390; HGNC ID: 5234
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04010MAPK signaling pathway
hsa03040Spliceosome
hsa04141Protein processing in endoplasmic reticulum
hsa04144Endocytosis
hsa05145Toxoplasmosis
hsa04612Antigen processing and presentation
No data
No data
Pathway IDPathway Name
P00049Parkinson disease
P00006Apoptosis signaling pathway
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1834Sarcoidosis
1848Embryoma
2205Uveitis
Desease Name
NORMALVARIATION
prostate cancer
graft-versus-host disease
CANCER
outcome after severe injury
Hearing Loss, Noise-Induced
IMMUNE
abacavir hypersensitivity
sarcoidosis
sarcoidosis uveitis
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D002220 Carbamazepine HSPA1L gene SNP affects the susceptibility to Carbamazepineaffects response to substance 16538175
D002259 Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of HSPA1L mRNAdecreases expression 16039398
D013759 Tetrahydrocannabinol Tetrahydrocannabinol results in decreased expression of HSPA1L mRNAdecreases expression 16039398
D004041 Dietary Fats Dietary Fats results in decreased expression of HSPA1L mRNAdecreases expression 18042831
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of HSPA1L mRNAincreases expression 15171707
C045651 epigallocatechin gallate epigallocatechin gallate results in decreased expression of HSPA1L mRNAdecreases expression 18851785
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of HSPA1L mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of HSPA1L mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of HSPA1L mRNAaffects cotreatment|increases expression 17942748
C056507 gemcitabine gemcitabine results in decreased expression of HSPA1L mRNAdecreases expression 17039268
D016627 Oxidopamine Oxidopamine results in increased expression of HSPA1L mRNAincreases expression 12486162
D009151 Mustard Gas Mustard Gas results in increased expression of HSPA1L mRNAincreases expression 18988085
D017239 Paclitaxel Paclitaxel analog results in increased expression of HSPA1L mRNAincreases expression 15585946
C041786 palm oil palm oil results in decreased expression of HSPA1L mRNAdecreases expression 18042831
C006253 pirinixic acid pirinixic acid results in increased expression of HSPA1L mRNAincreases expression 18301758
C017947 sodium arsenite sodium arsenite results in increased expression of HSPA1L mRNAincreases expression 16014739
D013629 Tamoxifen Tamoxifen affects the expression of HSPA1L mRNAaffects expression 17555576
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of HSPA1L mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of HSPA1L mRNAincreases expression 17942748
D013849 Thimerosal Thimerosal results in increased expression of HSPA1L mRNAincreases expression 16870260
D019287 Zinc Sulfate Zinc Sulfate results in increased expression of HSPA1L mRNAincreases expression 16330358
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.5214745880
MESH:D000014 Abnormalities, Drug-Induced Carbamazepine 8.588986270
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 8.5814514962 15322242 11752688
MESH:D000138 Acidosis Zinc Sulfate 4.877265320
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.9117505938
MESH:D055371 Acute Lung Injury pirinixic acid 3.0818653653
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.8014692618
MESH:D018248 Adenoma, Liver Cell pirinixic acid 9.7816434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 9.7816835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.6715276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.8716712894 17306315
MESH:D000686 Amyloidosis Diethylstilbestrol 4.4415469931
MESH:D000690 Amyotrophic Lateral Sclerosis Tetrahydrocannabinol 4.8015204022
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.9111748828
MESH:D000860 Anoxia Zinc Sulfate 4.987265320
MESH:D001161 Arteriosclerosis Dietary Fats 9.7815238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 9.7811256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.6415885639
MESH:D001249 Asthma epigallocatechin gallate 5.3216516891
MESH:D001249 Asthma Mustard Gas 5.3210378619
MESH:D050197 Atherosclerosis Tetrahydrocannabinol 4.4515815632
MESH:D001289 Attention Deficit Disorder with Hyperactivity Oxidopamine 4.6214699433
MESH:D001327 Autoimmune Diseases epigallocatechin gallate 5.0319761891
MESH:D001714 Bipolar Disorder Carbamazepine 4.1120046352 17594078
MESH:D001768 Blister Mustard Gas 5.1219167455
MESH:D001778 Blood Coagulation Disorders pirinixic acid 8.6319483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 8.6312125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.7615340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.7315746008
MESH:D001859 Bone Neoplasms Paclitaxel 4.5315867366
MESH:D001943 Breast Neoplasms Dietary Fats 2.9520435547
MESH:D001943 Breast Neoplasms Diethylstilbestrol 2.9515324884 17129689
MESH:D001943 Breast Neoplasms gemcitabine 2.9518382427 17039268
MESH:D001943 Breast Neoplasms Paclitaxel 2.9516244791 18234424 18323546 16115903 16273361 18223236 15136595 11325840
MESH:D001943 Breast Neoplasms Tamoxifen 2.9519142967 20065188 18629630 17242785 11161223 18997820 19189210 19200415 16202921 18425577 19155303 19244106 19084267 16273361 20135344 20005174 19011961 20390343 15668708 19288272 18351453 19103187 19189212 18984771 18855134 21138602 19115204 19059307 18815881 16818667 17893378 19066611 20544844 18821012 19221464 21152245 15565566 19289846 20859285 17049068 16873071 17440819 19487384 19410462 17261762
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.9520435547
MESH:D001989 Bronchiolitis Obliterans Mustard Gas 5.1215286001
MESH:D029481 Bronchitis, Chronic Mustard Gas 4.9517687719 10378619
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.7616835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.4719066611
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 6.5816924424 15948411
MESH:D006528 Carcinoma, Hepatocellular Paclitaxel 6.5816313753
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 6.5817306315 16507464 15276417
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 6.5816924424
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 2.3718572023
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.5717572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3416120746 18670907 18850075
MESH:D002375 Catalepsy Tetrahydrocannabinol 5.6910318961
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 2.9620056578 19524636
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.1216835633
MESH:D002779 Cholestasis Ethinyl Estradiol 7.6311677210 16919318 17333356 16105132 15861022 17681005 17110522
MESH:D002779 Cholestasis pirinixic acid 7.6319176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.0816354765 8697196 12621046 15340226 15668235
MESH:D015179 Colorectal Neoplasms Paclitaxel 2.4418802399
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.0214669216 17141729
MESH:D019465 Craniofacial Abnormalities Carbamazepine 2.859014606
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.8510048152 15322242 20055451
MESH:D003456 Cryptorchidism Diethylstilbestrol 4.5212952375 16002989
MESH:D003711 Demyelinating Diseases Tamoxifen 4.3219031437
MESH:D017449 Dermatitis, Allergic Contact Thimerosal 4.4915932584 16958921
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.4018249437
MESH:D002658 Developmental Disabilities Thimerosal 4.8115764492
MESH:D003924 Diabetes Mellitus, Type 2 epigallocatechin gallate 4.5816988119
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.5817107852
MESH:D003928 Diabetic Nephropathies Tamoxifen 3.4419279558
OMIM:607208 DRAVET SYNDROME Carbamazepine 5.4111748493
MESH:D004342 Drug Hypersensitivity marker/mechanism 16538175
MESH:D004342 Drug Hypersensitivity Carbamazepine 4.3820216337 16538176 16538175 15057820
MESH:D056486 Drug-Induced Liver Injury Carbamazepine 4.1217465707
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 4.1220420201
MESH:D004362 Drug Toxicity Carbamazepine 8.2920216337
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 8.2911462148
MESH:D050171 Dyslipidemias Dietary Fats 3.4218367378
MESH:D004487 Edema Mustard Gas 11.1911428631 11428647 11402378 9260866
MESH:D004487 Edema pirinixic acid 11.1912083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 11.1911000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.8718230668 15322242 16714409
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Carbamazepine 15.2217654737
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 15.2212538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 15.2219031437
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 4.6616402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 7.4715700306 16804899
MESH:D016889 Endometrial Neoplasms Tamoxifen 7.4720544844 17893378 16202921 19155303
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.9810568697 9294722
MESH:D004816 Epidermal Necrolysis, Toxic Carbamazepine 5.2120485159 19915237 18855540 16538176 16415921
MESH:D004831 Epilepsies, Myoclonic Carbamazepine 5.1717275665
MESH:D004828 Epilepsies, Partial Carbamazepine 4.9416628512 17116037 15008574
MESH:D004827 Epilepsy Carbamazepine 7.577988514 20417680 17178248 19620853 18234410 19700373 19439326 17465707 821787 9014606
MESH:D004827 Epilepsy Tetrahydrocannabinol 7.57821787
MESH:D017029 Epilepsy, Complex Partial Carbamazepine 5.317750514
MESH:D004830 Epilepsy, Tonic-Clonic Carbamazepine 5.0915276670 3659116
MESH:D004890 Erythema Mustard Gas 5.129357497
MESH:D004916 Erythromelalgia Carbamazepine 5.6919549232
MESH:D004938 Esophageal Neoplasms Paclitaxel 2.8816481741
MESH:D005076 Exanthema Carbamazepine 5.4320485159
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.9811564622
MESH:D005234 Fatty Liver Dietary Fats 18.4219551842 17967931 19004024 18296743
MESH:D005234 Fatty Liver Ethinyl Estradiol 18.4215345470
MESH:D005234 Fatty Liver pirinixic acid 18.4220131406 19236843
MESH:D005234 Fatty Liver Tamoxifen 18.4219224547 14986274
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 8.1216534752 16611131 16002989 16513791 15751030
MESH:D052776 Female Urogenital Diseases Tamoxifen 8.1216709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.4211858732
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.4914745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.1519069698
MESH:D005355 Fibrosis Dietary Fats 8.4918296743
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 8.4920067830
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 12.7016452187
MESH:D005833 Genital Neoplasms, Female sodium arsenite 12.7016452187
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.5710696789
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.3111294989 10048152
MESH:D006333 Heart Failure pirinixic acid 2.5120558911
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.2911000095
MESH:D006527 Hepatolenticular Degeneration Zinc Sulfate 4.9617063115
MESH:D006529 Hepatomegaly pirinixic acid 8.1319772884 16221962 18467677 19176532
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 8.1315340226 16120746 12621046
MESH:D006689 Hodgkin Disease sodium arsenite 3.1112676792
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.0216354765 8697196 16959395 15340226 18606429
MESH:D006937 Hypercholesterolemia Dietary Fats 3.5521332399
MESH:D006943 Hyperglycemia pirinixic acid 3.1420558911
MESH:D020138 Hyperhomocysteinemia Carbamazepine 4.6910459572
MESH:D006949 Hyperlipidemias Dietary Fats 3.5721332399
MESH:D006965 Hyperplasia Carbamazepine 11.1718773962
MESH:D006965 Hyperplasia Diethylstilbestrol 11.1712960047 14722030
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 1.8918850075 18670907
MESH:D007021 Hypospadias Diethylstilbestrol 11.1116002989
MESH:D007021 Hypospadias Ethinyl Estradiol 11.1116569931 16945680
MESH:D007022 Hypotension Zinc Sulfate 4.437265320
MESH:D007035 Hypothermia Tetrahydrocannabinol 5.8710318961
MESH:D007246 Infertility Diethylstilbestrol 4.3115036965
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.4212013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 6.5417937319
MESH:D007248 Infertility, Male sodium arsenite 6.5412646999 15346721
MESH:D007249 Inflammation Dietary Fats 11.7820412841
MESH:D007249 Inflammation Mustard Gas 11.7811428620 16001271 17524151 11428647 11402378 9357497 9260866 11428631 8975870
MESH:D007249 Inflammation Tamoxifen 11.7819457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 11.7812878042 12200463
MESH:D007333 Insulin Resistance Dietary Fats 7.1518457598 11836018
MESH:D007333 Insulin Resistance pirinixic acid 7.1516306350
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.2916580747
MESH:D007674 Kidney Diseases sodium arsenite 2.7720008137
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 7.4415003126 16762066 14681315
MESH:D007680 Kidney Neoplasms Tamoxifen 7.4418625569
MESH:D007859 Learning Disorders Diethylstilbestrol 4.0217184923
MESH:D016773 Leishmaniasis, Cutaneous Zinc Sulfate 4.2215237267
MESH:D008064 Lipidoses Tamoxifen 3.1217567588 15342952
MESH:D008080 Liposarcoma Paclitaxel 4.7817353645
MESH:D008103 Liver Cirrhosis Dietary Fats 2.8518296743
MESH:D008106 Liver Cirrhosis, Experimental epigallocatechin gallate 4.9317481882
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 4.9315474484
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 4.9318564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 4.9312878042
MESH:D008113 Liver Neoplasms Diethylstilbestrol 14.0716712894 15890375
MESH:D008113 Liver Neoplasms pirinixic acid 14.0716377806 20007298 15890375
MESH:D008113 Liver Neoplasms sodium arsenite 14.0716712894 15276417
MESH:D008113 Liver Neoplasms Tamoxifen 14.0716684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 14.0716984957
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 2.0812151625
MESH:D008171 Lung Diseases Mustard Gas 7.4418702808 18161513
MESH:D008171 Lung Diseases sodium arsenite 7.4419095001
MESH:D008175 Lung Neoplasms Mustard Gas 4.818781369 3148597
MESH:D008175 Lung Neoplasms sodium arsenite 4.8117077188 16712894 19931552 17306315 15276417
MESH:D008175 Lung Neoplasms Tamoxifen 4.8118625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 4.8119555203 11884234
MESH:D008180 Lupus Erythematosus, Systemic Carbamazepine 3.5616628512
MESH:D008181 Lupus Nephritis Diethylstilbestrol 5.1115166399
MESH:D008223 Lymphoma Diethylstilbestrol 3.4415700306
MESH:D008228 Lymphoma, Non-Hodgkin Paclitaxel 4.0514749477
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 5.4916002989
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.7219428831
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 2.5911731420 19196723 14580682 19196722 16827153
MESH:D020149 Manganese Poisoning Tamoxifen 4.5219453300
MESH:D008545 Melanoma epigallocatechin gallate 7.3111746506 17992120
MESH:D008545 Melanoma Paclitaxel 7.3112040289 12025231 16342250
MESH:D008545 Melanoma sodium arsenite 7.3119082730 16487513
MESH:D008545 Melanoma Tamoxifen 7.3112393984 19393235
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.1515990972
MESH:D008607 Mental Retardation Carbamazepine 3.719014606
MESH:D009101 Multiple Myeloma Paclitaxel 3.6514749477
MESH:D009134 Muscular Atrophy, Spinal epigallocatechin gallate 5.4617962980
MESH:D009135 Muscular Diseases pirinixic acid 3.4716239165
MESH:D009203 Myocardial Infarction pirinixic acid 2.1219151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.9812213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.9116411023
MESH:D009224 Myotonia Congenita Carbamazepine 5.4320399394
MESH:D009362 Neoplasm Metastasis Paclitaxel 5.9215867366
MESH:D009362 Neoplasm Metastasis Tamoxifen 5.9219393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.5019410462
MESH:D009369 Neoplasms Diethylstilbestrol 8.1615313581
MESH:D009369 Neoplasms pirinixic acid 8.1617405874
MESH:D009369 Neoplasms sodium arsenite 8.1611559025
MESH:D009374 Neoplasms, Experimental sodium arsenite 3.6320056578
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.9719196722 19189210 19200415
MESH:D009421 Nervous System Malformations Carbamazepine 16.3216990009
MESH:D009421 Nervous System Malformations Diethylstilbestrol 16.3211399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 16.3214600291
MESH:D009436 Neural Tube Defects sodium arsenite 7.8112854658
MESH:D009436 Neural Tube Defects Tetrahydrocannabinol 7.8119040278
MESH:D019636 Neurodegenerative Diseases Oxidopamine 4.7218514411
MESH:D009503 Neutropenia Mustard Gas 3.9316761898 7688884
MESH:D009765 Obesity Dietary Fats 4.4020518802 21332399 18457598 17217161 16723640 11836018 19632207 20132043 18674790
MESH:D009765 Obesity pirinixic acid 4.4020558911
MESH:D010014 Osteolysis Paclitaxel 4.9415867366
MESH:D010018 Osteomalacia Carbamazepine 5.4317016548
MESH:D010051 Ovarian Neoplasms Paclitaxel 5.0811161223
MESH:D010051 Ovarian Neoplasms sodium arsenite 5.0815276417 17306315
MESH:D010146 Pain Carbamazepine 4.0015215642
MESH:D010190 Pancreatic Neoplasms gemcitabine 3.5216929163 11504793 18992248 17440100 18383843
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.6511578682
MESH:D010267 Parapsoriasis Carbamazepine 5.6616538176
MESH:D010302 Parkinson Disease, Secondary Oxidopamine 5.4215893579 11771942
OMIM:167400 PAROXYSMAL EXTREME PAIN DISORDER Carbamazepine 5.8917679678 17145499
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.2212520081
MESH:D010900 Pituitary Diseases Diethylstilbestrol 5.1414722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 4.6315687265 16977796
MESH:D011041 Poisoning Mustard Gas 3.7615727166
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.5218163543
MESH:D011248 Pregnancy Complications Carbamazepine 5.119014606
MESH:D011297 Prenatal Exposure Delayed Effects Carbamazepine 16.219014606
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 16.2117184923
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 16.2111118676 11222880 11896295 11399792
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 2.1315046698 15846301 17136230
MESH:D011471 Prostatic Neoplasms Paclitaxel 2.1317172428 16729912 17136230 16356831
MESH:D011471 Prostatic Neoplasms sodium arsenite 2.1316039940
MESH:D011471 Prostatic Neoplasms Tamoxifen 2.1315067354
MESH:D011537 Pruritus Ethinyl Estradiol 9.4115861022 16919318
MESH:D011537 Pruritus Mustard Gas 9.4118058305
MESH:D019310 Pseudolymphoma Carbamazepine 5.579591791 12752131
MESH:D011658 Pulmonary Fibrosis Mustard Gas 2.9117620002 17266442 10334151 17894541 17720292
MESH:D015427 Reperfusion Injury pirinixic acid 2.3619058328
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.8018990726
MESH:D012640 Seizures Carbamazepine 3.7615946322 16876388 19414003 9844417 16938433 9046859 16180713
MESH:D012871 Skin Diseases Mustard Gas 2.7016961503 12880345 15451306
MESH:D012878 Skin Neoplasms sodium arsenite 5.5219524636 18572023
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.5216192470
MESH:D012893 Sleep Disorders Carbamazepine 5.0919414003
MESH:D013088 Spermatocele Diethylstilbestrol 19.9816002989 16709447
MESH:D013088 Spermatocele Ethinyl Estradiol 19.9816709447
MESH:D013088 Spermatocele Tamoxifen 19.9816709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 4.0019457130
MESH:D016135 Spinal Dysraphism sodium arsenite 3.7612854658
MESH:D013262 Stevens-Johnson Syndrome Carbamazepine 5.1716538176 18855540 19694795 20485159 19915237 16415921 15057820
MESH:D013274 Stomach Neoplasms Paclitaxel 2.4418396642 18506536
MESH:D024801 Tauopathies Paclitaxel 4.7816930453
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.5811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.1115669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.8712697716
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 8.2916452187 17306315 16712894
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 8.2917306315 11723127 16712894 16452187
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 8.2916712894 8653321 17572228
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 9.4116175088
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 9.4111813266
MESH:D014591 Uterine Diseases Diethylstilbestrol 5.1414652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 9.3415809267 16690809
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 9.3414692618
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 4.4016002989 16513791
MESH:D014652 Vascular Diseases sodium arsenite 4.3917056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.5712125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.5014671159 15869587
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.2215886252
MESH:D015430 Weight Gain Dietary Fats 3.7016723640
Pathway ID Pathway Name
KEGG:04612 Antigen processing and presentation
KEGG:04144 Endocytosis
KEGG:04010 MAPK signaling pathway
KEGG:05162 Measles
KEGG:04141 Protein processing in endoplasmic reticulum
KEGG:03040 Spliceosome
KEGG:05145 Toxoplasmosis
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA29500
    • No data
    Releated disease ID Related disease Name
    PA443936Drug Hypersensitivity
    PA444059Epidermal Necrolysis, Toxic
    PA445738Stevens-Johnson Syndrome
    Releated drug ID Related drug Name
    PA451788trimethoprim
    PA448785carbamazepine
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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