AutismKB 2.0

Annotation Detail for DNAJB1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:DNAJB1 ( HSPF1,Hdj1,Hsp40,RSPH16B,Sis1 )
Gene Full Name: DnaJ (Hsp40) homolog, subfamily B, member 1
Band: 19p13.12
Quick LinksEntrez ID:3337; OMIM: 604572; Uniprot ID:DNJB1_HUMAN; ENSEMBL ID: ENSG00000132002; HGNC ID: 5270
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04141Protein processing in endoplasmic reticulum
No data
No data
No data
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1850Herpes
2045Bipolar disorder
2069Schizophrenia
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of DNAJB1 mRNAaffects expression 21346803
C026137 3-hydroxyacetanilide 3-hydroxyacetanilide results in decreased expression of DNAJB1 mRNAdecreases expression 18544908
C035207 4-amino-2,6-dinitrotoluene 4-amino-2,6-dinitrotoluene affects the expression of DNAJB1 mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of DNAJB1 mRNAaffects expression 17562736
15606129
D000082 Acetaminophen Acetaminophen results in increased expression of DNAJB1 mRNAincreases expression 12540782
18544908
11264010
D000082 Acetaminophen O(2)-vinyl-1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate inhibits the reaction [Acetaminophen results in increased expression of DNAJB1 mRNA]decreases reaction|increases expression 12540782
D000082 Acetaminophen Acetaminophen affects the expression of DNAJB1 mRNAaffects expression 18246545
D000082 Acetaminophen Acetaminophen results in increased expression of DNAJB1 mRNAincreases expression 18246545
18346771
17202762
C006632 arsenic trioxide arsenic trioxide results in increased expression of DNAJB1 mRNAincreases expression 19417148
20458559
C072553 benzyloxycarbonylleucyl-leucyl-leucine aldehyde benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of DNAJB1 proteinincreases expression 15525353
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in decreased expression of DNAJB1 mRNAdecreases expression 15336504
D002104 Cadmium Cadmium results in increased expression of DNAJB1 mRNAincreases expression 11985888
D002104 Cadmium Cadmium results in increased expression of DNAJB1 proteinincreases expression 16729991
D019256 Cadmium Chloride Cadmium Chloride results in increased expression of DNAJB1 mRNAincreases expression 11985888
D019256 Cadmium Chloride Cadmium Chloride results in increased expression of DNAJB1 proteinincreases expression 16729991
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of DNAJB1 mRNAincreases expression 18346771
D003520 Cyclophosphamide Cyclophosphamide affects the expression of DNAJB1 mRNAaffects expression 18246545
D016572 Cyclosporine Cyclosporine results in increased expression of DNAJB1 mRNAincreases expression 20106945
D004041 Dietary Fats Dietary Fats results in increased expression of DNAJB1 mRNAincreases expression 18042831
D004052 Diethylnitrosamine Diethylnitrosamine results in decreased expression of DNAJB1 mRNAdecreases expression 18691550
D004052 Diethylnitrosamine IKBKB protein inhibits the reaction [Diethylnitrosamine results in decreased expression of DNAJB1 mRNA]decreases expression|decreases reaction 18691550
D004052 Diethylnitrosamine [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of DNAJB1 mRNAaffects cotreatment|decreases expression 18253720
D004642 Emodin Emodin results in increased expression of DNAJB1 mRNAincreases expression 16045814
C044101 endotoxin, Escherichia coli endotoxin, Escherichia coli results in increased expression of DNAJB1 mRNAincreases expression 15919760
D004958 Estradiol Estradiol results in increased expression of DNAJB1 mRNAincreases expression 20106945
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of DNAJB1 mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of DNAJB1 mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of DNAJB1 mRNAaffects cotreatment|increases expression 17942748
D011345 Fenofibrate [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of DNAJB1 mRNAaffects cotreatment|decreases expression 18253720
C020748 ferrous sulfate DNAJB1 protein results in decreased susceptibility to ferrous sulfatedecreases response to substance 11359866
D005912 Gliotoxin Gliotoxin results in increased expression of DNAJB1 mRNAincreases expression 18346771
D006861 Hydrogen Peroxide DNAJB1 protein results in decreased susceptibility to Hydrogen Peroxidedecreases response to substance 11359866
C031927 hydroquinone hydroquinone results in increased expression of DNAJB1 mRNAincreases expression 15452088
C013038 hydroxyhydroquinone hydroxyhydroquinone results in increased expression of DNAJB1 mRNAincreases expression 17572062
D007213 Indomethacin Indomethacin results in increased expression of DNAJB1 mRNAincreases expression 18299717
C482199 lipopolysaccharide, E coli O55-B5 lipopolysaccharide, E coli O55-B5 results in increased expression of DNAJB1 mRNAincreases expression 18346771
D008070 Lipopolysaccharides Lipopolysaccharides results in increased expression of DNAJB1 mRNAincreases expression 15919760
C107010 O(2)-vinyl-1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate O(2)-vinyl-1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate inhibits the reaction [Acetaminophen results in increased expression of DNAJB1 mRNA]decreases reaction|increases expression 12540782
C041786 palm oil palm oil results in increased expression of DNAJB1 mRNAincreases expression 18042831
D010269 Paraquat DNAJB1 protein results in decreased susceptibility to Paraquatdecreases response to substance 11359866
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in increased expression of DNAJB1 mRNA]affects reaction|increases expression 19482888
D010634 Phenobarbital Phenobarbital results in decreased expression of DNAJB1 mRNAdecreases expression 19270015
D010634 Phenobarbital Phenobarbital results in increased expression of DNAJB1 mRNAincreases expression 19482888
D016226 Phosphorus, Dietary Phosphorus, Dietary affects the expression of DNAJB1 mRNAaffects expression 17651324
C006253 pirinixic acid pirinixic acid results in decreased expression of DNAJB1 mRNAdecreases expression 17426115
C006253 pirinixic acid pirinixic acid results in increased expression of DNAJB1 mRNAincreases expression 18301758
D011374 Progesterone Progesterone results in increased expression of DNAJB1 mRNAincreases expression 18037150
C045950 propiconazole propiconazole results in increased expression of DNAJB1 mRNAincreases expression 19363144
C487081 PXD101 PXD101 results in increased expression of DNAJB1 mRNAincreases expression 19606018
C031280 pyrazole pyrazole results in increased expression of DNAJB1 mRNAincreases expression 17945193
D020849 Raloxifene Raloxifene results in increased expression of DNAJB1 mRNAincreases expression 16497877
C064116 S-(1,1,2,2-tetrafluoroethyl)cysteine S-(1,1,2,2-tetrafluoroethyl)cysteine results in increased expression of DNAJB1 mRNAincreases expression 16678137
C515055 S-(dimethylarsino)-glutathione S-(dimethylarsino)-glutathione results in increased expression of DNAJB1 mRNAincreases expression 19417148
C017947 sodium arsenite sodium arsenite results in increased expression of DNAJB1 mRNAincreases expression 12679051
12760830
C017947 sodium arsenite sodium arsenite results in increased expression of DNAJB1 proteinincreases expression 16729991
C017947 sodium arsenite sodium arsenite results in increased expression of DNAJB1 mRNAincreases expression 16014739
C017947 sodium arsenite sodium arsenite results in increased expression of DNAJB1 proteinincreases expression 16729991
C016104 sodium bichromate sodium bichromate results in decreased expression of DNAJB1 mRNAdecreases expression 12760830
D013629 Tamoxifen Tamoxifen affects the expression of DNAJB1 mRNAaffects expression 17555576
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of DNAJB1 mRNAincreases expression 20106945
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of DNAJB1 mRNAaffects cotreatment|increases expression 17942748
D013849 Thimerosal Thimerosal results in increased expression of DNAJB1 mRNAincreases expression 16870260
C012589 trichostatin A trichostatin A results in increased expression of DNAJB1 mRNAincreases expression 19606018
D001335 Vehicle Emissions Vehicle Emissions results in increased expression of DNAJB1 mRNAincreases expression 19465080
C025643 vinclozolin vinclozolin affects the expression of DNAJB1 mRNAaffects expression 19015723
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.0314745880
MESH:D000014 Abnormalities, Drug-Induced 4-amino-2,6-dinitrotoluene 11.347525203
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 11.346195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 11.3411752688 15322242 14514962
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.4217505938
MESH:D055371 Acute Lung Injury Lipopolysaccharides 7.4918653653 11850527
MESH:D055371 Acute Lung Injury pirinixic acid 7.4918653653
MESH:D000230 Adenocarcinoma arsenic trioxide 8.8819825857 11798837
MESH:D000230 Adenocarcinoma Estradiol 8.8811473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 8.8814692618
MESH:D000230 Adenocarcinoma Indomethacin 8.8816537180
MESH:D000236 Adenoma Diethylnitrosamine 5.896695378 10737359
MESH:D000236 Adenoma Indomethacin 5.8911497255
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 20.6917620307 19061943 19052882 17162532 18056438 16434500
MESH:D018248 Adenoma, Liver Cell Phenobarbital 20.6917620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 20.6916434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 20.6916835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.1815276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.3816712894 17306315
MESH:D000382 Agricultural Workers' Diseases Paraquat 3.2711874814
MESH:D000419 Albuminuria Raloxifene 4.1117451421 17308373
MESH:D016301 Alveolar Bone Loss Indomethacin 4.8517225004
MESH:D000544 Alzheimer Disease Indomethacin 4.0017627676 15579461
MESH:D000544 Alzheimer Disease Raloxifene 4.0015800139
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.5111748828
MESH:D000799 Angioedema Acetaminophen 3.3310982225
MESH:D001008 Anxiety Disorders vinclozolin 3.2419015723
MESH:D001014 Aortic Aneurysm Indomethacin 4.3710231640
MESH:D017544 Aortic Aneurysm, Abdominal Indomethacin 4.3810388637
MESH:D001161 Arteriosclerosis Cyclophosphamide 14.2015014928
MESH:D001161 Arteriosclerosis Dietary Fats 14.2015238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 14.2011256880
MESH:D018771 Arthralgia Indomethacin 4.652160914
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.3415885639
MESH:D001172 Arthritis, Rheumatoid Indomethacin 2.6911248219
MESH:D050197 Atherosclerosis Cadmium 3.3315687053
MESH:D001321 Autistic Disorder Acetaminophen 1.4818445737
MESH:D001477 Bartter Syndrome Indomethacin 4.4910684365
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 18.3016206674
MESH:D001778 Blood Coagulation Disorders ferrous sulfate 18.306421970
MESH:D001778 Blood Coagulation Disorders pirinixic acid 18.3019483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 18.3012125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.2715340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.4315746008
MESH:D001929 Brain Edema Indomethacin 4.5111481608
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 4.8217868700
MESH:D001930 Brain Injuries Progesterone 9.3215845082 15380490 15665606
MESH:D001930 Brain Injuries Raloxifene 9.3216580743
MESH:D002545 Brain Ischemia Indomethacin 3.9112524144
MESH:D001943 Breast Neoplasms Cyclophosphamide 5.1815093573 17388661 15136595 18234424 16978400 17020986 18323546 11325840 12006526
MESH:D001943 Breast Neoplasms Dietary Fats 5.1820435547
MESH:D001943 Breast Neoplasms Diethylnitrosamine 5.1817474063
MESH:D001943 Breast Neoplasms Estradiol 5.1812948864 17018787 17261762 19861407 16675129 14630087 17289903 18497071
MESH:D001943 Breast Neoplasms Indomethacin 5.1817401462
MESH:D001943 Breast Neoplasms Progesterone 5.1817614352 16175315 15562024
MESH:D001943 Breast Neoplasms Raloxifene 5.1816912660 15572757 15758505 17893378 17261762 16837676 17952589 17595753 17242785 15775269 17440819 17049068
MESH:D001943 Breast Neoplasms Tamoxifen 5.1817440819 15565566 19288272 19189212 19059307 19200415 16873071 18629630 19410462 18815881 16273361 19189210 20859285 21152245 21138602 20135344 19103187 17261762 19244106 19084267 19487384 20390343 17049068 11161223 18855134 19115204 20065188 17893378 18425577 19011961 18351453 19155303 20005174 20544844 18984771 19142967 18997820 15668708 16202921 19221464 17242785 19289846 16818667 19066611 18821012
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 5.1820435547
MESH:D002051 Burkitt Lymphoma arsenic trioxide 3.8611589617
MESH:D002056 Burns Indomethacin 4.2110459503
MESH:D002100 Cachexia Indomethacin 4.5015625704 16537180 11239499 15141370
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 3.9516111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.2915673190 16124888 16227642 16011737 15700767 16097048 3786805 16050911 15721981 16192424 10355542 18705752
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.4016835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.0119066611
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 23.5916705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 23.593084413
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 23.5915073043 16217749 15553829 14691202 11135700
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 23.5918788625
MESH:D006528 Carcinoma, Hepatocellular Cyclophosphamide 23.5919701751
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 23.5910737359 17978847 20524982 16288022 18691550 19171122 21159647 19394651 16830150 3581430 20512989 17761372 16540662 19335982 19383236 17138121 19208518 19519916 16502159 20084675 20101231 17173139 16807293 17428255 18785209 20935162 19822196 20514400 20432363 18788625 11831363 19919837 16328049 16878318 19107877 16569478 18971187 16935385 16681979 19052882 16779866 3084413 18494052 18506893 18978308 18210153 20727157 19539802 18665156 17055752 19418558 20214788 20007298 18393292 17162532 10672840 18056438 19701751 16698587
MESH:D006528 Carcinoma, Hepatocellular Estradiol 23.5916924424
MESH:D006528 Carcinoma, Hepatocellular Indomethacin 23.5916391822
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 23.5920007298 17173139 1701930 20935162 6705139
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 23.5917306315 15276417 16507464
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 23.5916924424
MESH:D018827 Carcinoma, Lewis Lung Cyclophosphamide 9.8516152834
MESH:D018827 Carcinoma, Lewis Lung Indomethacin 9.8511053908
MESH:D018276 Carcinoma, Medullary Indomethacin 4.8411352223 14736730 18791128
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.3619014326
MESH:D002292 Carcinoma, Renal Cell Cyclophosphamide 6.0816201981
MESH:D002292 Carcinoma, Renal Cell Indomethacin 6.0817341418
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.6712490120
MESH:D002294 Carcinoma, Squamous Cell Indomethacin 4.3212636206 15482327
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 4.3218572023
MESH:D002295 Carcinoma, Transitional Cell Raloxifene 8.0317572228
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 8.0317572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.0718850075 18670907 16120746
MESH:D002318 Cardiovascular Diseases Hydrogen Peroxide 6.3816936243
MESH:D002318 Cardiovascular Diseases Raloxifene 6.3815775269
MESH:D002386 Cataract 4-amino-2,6-dinitrotoluene 6.3814694615
MESH:D002386 Cataract Acetaminophen 6.3810977129
MESH:D002471 Cell Transformation, Neoplastic Cadmium 17.3017332340
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 17.3012371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 17.307505956 21159647 17174075 2727394
MESH:D002471 Cell Transformation, Neoplastic Estradiol 17.3018566989
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 17.3020056578 19524636
MESH:D002493 Central Nervous System Diseases Phenobarbital 3.764080065
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 7.9019052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 7.9016835633
MESH:D002764 Cholecystitis Indomethacin 4.6511181007
MESH:D002779 Cholestasis Cyclosporine 11.1319486331
MESH:D002779 Cholestasis Ethinyl Estradiol 11.1317110522 16919318 17333356 11677210 15861022 16105132 17681005
MESH:D002779 Cholestasis pirinixic acid 11.1319176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 1.8716354765 8697196 12621046 15668235 15340226
MESH:D003072 Cognition Disorders Raloxifene 4.1215800139
MESH:D003110 Colonic Neoplasms Indomethacin 2.5015625704 15936596 15786552 15637740 11260862 15963497
MESH:D015179 Colorectal Neoplasms arsenic trioxide 2.5320501625
MESH:D015179 Colorectal Neoplasms Indomethacin 2.5312606626 11197048 18059344 17054584
MESH:D000013 Congenital Abnormalities 4-amino-2,6-dinitrotoluene 7.7615095906
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 7.7614669216 17141729
MESH:D023903 Coronary Restenosis arsenic trioxide 3.7012609071
MESH:D018352 Coronavirus Infections Indomethacin 5.2017302372
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 2.2810525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.2810048152 15322242 20055451
MESH:D003456 Cryptorchidism vinclozolin 3.8614966744
MESH:D003490 Cyanosis 2,4-dinitrotoluene 3.5218551238
MESH:D003556 Cystitis Cyclophosphamide 4.4718483878 15643279 12161096 16614059 11948286 18372110 17010015 10498854 16651033 15276878 18295254 12388444 16989017 18093676 18433785 16413132 17979934 18710439 10700343 12913760
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.6315213294
MESH:D003711 Demyelinating Diseases Tamoxifen 3.8719031437
MESH:D003865 Depressive Disorder, Major Raloxifene 3.7317474826
MESH:D017449 Dermatitis, Allergic Contact Thimerosal 4.0715932584 16958921
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.1718249437
MESH:D002658 Developmental Disabilities Thimerosal 4.4915764492
MESH:D003921 Diabetes Mellitus, Experimental Cyclophosphamide 3.6510990075 15331540 11751995
MESH:D003922 Diabetes Mellitus, Type 1 Cyclophosphamide 3.0518772604
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 3.7220387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 3.7217107852
MESH:D003928 Diabetic Nephropathies Estradiol 12.5419279558
MESH:D003928 Diabetic Nephropathies Raloxifene 12.5417308373 17451421 15920148
MESH:D003928 Diabetic Nephropathies Tamoxifen 12.5419279558
MESH:D003929 Diabetic Neuropathies Progesterone 4.0017187935
MESH:D003967 Diarrhea Indomethacin 3.337237001 7907874
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 22.3321346803 18551238
MESH:D056486 Drug-Induced Liver Injury 4-amino-2,6-dinitrotoluene 22.3321346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 22.3319923254 12705907 2444490 11421492 11743745 14986274 16393943 12958197 12594235 19739265 12153990 10915739 16485898 16081117 15619225 14725611 19164858 11461765 12540782 11287661 17562736 16781746 18713872 11529661 19370779 16227642 11739529 19416960 19085960 10663392 19420014 17906064 12392966 17522070 10774834 14550746 15968718 11834606 16177239 18071297 16109766
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 22.3315027814 7120509 10092053 4309450 11566570 9327722 3786805 16177239 7179309 19085960 19336974 15968718 6623471 7440962 6884620 10915739 15998439 21278145 16227642 2869522 3732212 17522070
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 22.3319107877
MESH:D056486 Drug-Induced Liver Injury Gliotoxin 22.3319739265
MESH:D056486 Drug-Induced Liver Injury O(2)-vinyl-1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate 22.3312540782
MESH:D056486 Drug-Induced Liver Injury pyrazole 22.3312499123
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 22.3320420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.5819426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.3811462148
MESH:D004374 Ductus Arteriosus, Patent Indomethacin 4.6412774134 16326151 16133044 17190690 18446180 18043480
MESH:D004381 Duodenal Ulcer Indomethacin 3.6616699067 11535926 11595415 11595431 11991626 17202747 17351913 17045617 17151854 17329845 10671773
MESH:D050171 Dyslipidemias Dietary Fats 7.7118367378
MESH:D050171 Dyslipidemias Fenofibrate 7.7116707586
MESH:D004421 Dystonia Phenobarbital 3.541851702
MESH:D004487 Edema Indomethacin 12.778985016 7990266 8273558 19703484 10653021 7907874 16100529
MESH:D004487 Edema pirinixic acid 12.7712083418
MESH:D004487 Edema Raloxifene 12.7715860553
MESH:D004487 Edema Tetrachlorodibenzodioxin 12.7711000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.3816714409 15322242 18230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 17.9812538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 17.9817692515
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Raloxifene 17.9815845917
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 17.9819031437
MESH:D004701 Endocrine Gland Neoplasms trichostatin A 5.1219294695
MESH:D016889 Endometrial Neoplasms Estradiol 10.5611473722 18566989 19148513
MESH:D016889 Endometrial Neoplasms Fenofibrate 10.5616569247
MESH:D016889 Endometrial Neoplasms Tamoxifen 10.5619155303 20544844 16202921 17893378
MESH:D004715 Endometriosis Indomethacin 12.7515652904
MESH:D004715 Endometriosis Progesterone 12.7516134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 12.759294722 10568697
MESH:D019446 Endotoxemia endotoxin, Escherichia coli 14.8417637181 18509659
MESH:D019446 Endotoxemia Indomethacin 14.8418509659
MESH:D019446 Endotoxemia Lipopolysaccharides 14.8415821434 17637181 15328337
MESH:D004751 Enteritis Indomethacin 4.2317763956 10567023 16328016
MESH:D020345 Enterocolitis, Necrotizing Indomethacin 4.4917980183
MESH:D004802 Eosinophilia Cyclophosphamide 7.6011006010
MESH:D004802 Eosinophilia Indomethacin 7.6011298111
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 3.613659116
MESH:D004828 Epilepsies, Partial Phenobarbital 3.363922381 11558140
MESH:D004827 Epilepsy Phenobarbital 2.6120417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.126401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 3.767750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 3.513659116
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.6016302075
MESH:D004938 Esophageal Neoplasms arsenic trioxide 4.2112903497
MESH:D004938 Esophageal Neoplasms Indomethacin 4.2111005569
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.6311564622
MESH:D005234 Fatty Liver arsenic trioxide 40.8915073043
MESH:D005234 Fatty Liver Carbon Tetrachloride 40.8912631006 61145 15959796 16239168 12795759 19224547 17595544 16045604
MESH:D005234 Fatty Liver Cyclosporine 40.8919224547
MESH:D005234 Fatty Liver Dietary Fats 40.8918296743 17967931 19551842 19004024
MESH:D005234 Fatty Liver Diethylnitrosamine 40.8920387270 21071580
MESH:D005234 Fatty Liver Ethinyl Estradiol 40.8915345470
MESH:D005234 Fatty Liver pirinixic acid 40.8920131406 19236843
MESH:D005234 Fatty Liver Raloxifene 40.8917473493
MESH:D005234 Fatty Liver Tamoxifen 40.8919224547 14986274
MESH:D052776 Female Urogenital Diseases Tamoxifen 2.9116709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 2.9611858732
MESH:D005334 Fever endotoxin, Escherichia coli 12.9316997862
MESH:D005334 Fever Indomethacin 12.9311852909 17627676 10431976
MESH:D005334 Fever Lipopolysaccharides 12.9311852909 9205823
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.0214745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 3.6719069698
MESH:D005354 Fibrosarcoma Indomethacin 4.3910962813
MESH:D005355 Fibrosis Carbon Tetrachloride 28.1018705752
MESH:D005355 Fibrosis Cyclosporine 28.1012639820 12168785
MESH:D005355 Fibrosis Dietary Fats 28.1018296743
MESH:D005355 Fibrosis Emodin 28.1019474275
MESH:D005355 Fibrosis Indomethacin 28.1017994277
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 28.1020067830
MESH:D005499 Folliculitis Indomethacin 4.6511298111
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.7816904648
MESH:D005756 Gastritis Acetaminophen 9.4316983495
MESH:D005756 Gastritis Indomethacin 9.4315046732
MESH:D030342 Genetic Diseases, Inborn vinclozolin 4.4316973722
MESH:D005832 Genital Diseases, Male vinclozolin 4.7816417039
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.1716452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.718708960
MESH:D005909 Glioblastoma Indomethacin 6.4912870263
MESH:D005909 Glioblastoma trichostatin A 6.4918801729
MESH:D005910 Glioma Indomethacin 3.0118371953 16487511
MESH:D018316 Gliosarcoma Cyclophosphamide 5.0011389073
MESH:D005911 Gliosis Paraquat 4.6511124998
MESH:D005923 Glomerulosclerosis, Focal Segmental Indomethacin 3.8811849393
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.0810696789
MESH:D006073 Gout Indomethacin 4.8411248219
MESH:D006086 Graft vs Host Disease Cyclophosphamide 4.5415172196 16376943 11014644
MESH:D006258 Head and Neck Neoplasms Indomethacin 3.3915482327
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.0510048152 11294989
MESH:D006331 Heart Diseases Raloxifene 3.1811110106
MESH:D006333 Heart Failure pirinixic acid 2.2120558911
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 3.9115720958
MESH:D006463 Hemolytic-Uremic Syndrome Lipopolysaccharides 3.9416366002
MESH:D006467 Hemophilia A Cyclophosphamide 4.7911918545
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.8811000095
MESH:D006501 Hepatic Encephalopathy Indomethacin 4.1115633222
MESH:D006504 Hepatic Veno-Occlusive Disease Cyclophosphamide 5.0214986274
MESH:D006505 Hepatitis Carbon Tetrachloride 3.1219900420 19110552
MESH:D019698 Hepatitis C, Chronic Indomethacin 4.2015135802
MESH:D006529 Hepatomegaly Phenobarbital 16.6616109766
MESH:D006529 Hepatomegaly pirinixic acid 16.6618467677 19772884 19176532 16221962
MESH:D006529 Hepatomegaly propiconazole 16.6617178688 17178689
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 16.6615340226 12621046 16120746
MESH:D006558 Herpes Genitalis Estradiol 4.5115709030
MESH:D006689 Hodgkin Disease Cyclophosphamide 6.2117606976 16135485
MESH:D006689 Hodgkin Disease sodium arsenite 6.2112676792
MESH:D019584 Hot Flashes Estradiol 3.2417088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.5316959395 18606429 16354765 15340226 8697196
MESH:D006930 Hyperalgesia Acetaminophen 6.4916870215
MESH:D006930 Hyperalgesia Indomethacin 6.4912727271
MESH:D034321 Hyperamylasemia Indomethacin 5.2017883296
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.0216899240
MESH:D006937 Hypercholesterolemia Dietary Fats 3.1421332399
MESH:D006940 Hyperemia Indomethacin 4.5012524144
MESH:D006943 Hyperglycemia pirinixic acid 2.7420558911
MESH:D006949 Hyperlipidemias Dietary Fats 7.7921332399
MESH:D006949 Hyperlipidemias Indomethacin 7.7917546600
MESH:D006973 Hypertension Cyclosporine 7.3010903974
MESH:D006973 Hypertension Raloxifene 7.3017577099 15787275
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 7.3018670907 18850075
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.5915338365
MESH:D007021 Hypospadias Ethinyl Estradiol 3.3116945680 16569931
MESH:D007077 Ileal Diseases Indomethacin 4.5118306037 10574470
MESH:D007079 Ileitis Indomethacin 4.8416133968 10647630 10651667
MESH:D007154 Immune System Diseases Cyclophosphamide 4.8116076520
MESH:D007235 Infant, Premature, Diseases Indomethacin 4.8516133044
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 3.9115869954
MESH:D007247 Infertility, Female Ethinyl Estradiol 2.9912013081
MESH:D007248 Infertility, Male Cyclophosphamide 17.4116517039 7193160
MESH:D007248 Infertility, Male Ethinyl Estradiol 17.4117937319
MESH:D007248 Infertility, Male Paraquat 17.414850670
MESH:D007248 Infertility, Male sodium arsenite 17.4115346721 12646999
MESH:D007248 Infertility, Male vinclozolin 17.4116467254
MESH:D007249 Inflammation Dietary Fats 19.8720412841
MESH:D007249 Inflammation Diethylnitrosamine 19.8718785209
MESH:D007249 Inflammation Indomethacin 19.873291741 12568917 7812673
MESH:D007249 Inflammation Lipopolysaccharides 19.8717255318 12878042 17963957 9205823 17237260
MESH:D007249 Inflammation Progesterone 19.8715869954
MESH:D007249 Inflammation Tamoxifen 19.8719457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 19.8712200463 12878042
MESH:D007333 Insulin Resistance Dietary Fats 10.3018457598 11836018
MESH:D007333 Insulin Resistance Estradiol 10.3016393666 16627594
MESH:D007333 Insulin Resistance pirinixic acid 10.3016306350
MESH:D007410 Intestinal Diseases Indomethacin 3.8318236018 15610444 17994277 10210152 11686837 11713966 11855677 17329856 15831440
MESH:D019586 Intracranial Hypertension Indomethacin 4.8515241188
MESH:D019189 Iron Metabolism Disorders Lipopolysaccharides 4.1617255318
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 2.8816580747
MESH:D007579 Jejunal Diseases Indomethacin 4.5110574470 18306037 16133968
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 3.9215604871
MESH:D007674 Kidney Diseases Acetaminophen 24.1115629191 12587719
MESH:D007674 Kidney Diseases Cadmium 24.1116322080 16226777 16962696
MESH:D007674 Kidney Diseases Cadmium Chloride 24.1116962696
MESH:D007674 Kidney Diseases Cyclosporine 24.1118776723 10903974 8314463
MESH:D007674 Kidney Diseases Estradiol 24.1115618244
MESH:D007674 Kidney Diseases Indomethacin 24.1117190690
MESH:D007674 Kidney Diseases sodium arsenite 24.1120008137
MESH:D007676 Kidney Failure, Chronic Hydrogen Peroxide 3.8216518626
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 14.3516705839
MESH:D007680 Kidney Neoplasms Cyclosporine 14.3512371664
MESH:D007680 Kidney Neoplasms Estradiol 14.3515610895
MESH:D007680 Kidney Neoplasms Tamoxifen 14.3518625569
MESH:D007889 Leiomyoma Raloxifene 4.0316973256
MESH:D016773 Leishmaniasis, Cutaneous Indomethacin 3.4911703811 12228301 10320625
MESH:D007938 Leukemia arsenic trioxide 5.6915070760
MESH:D007938 Leukemia Cyclophosphamide 5.6910602166
MESH:D015451 Leukemia, Lymphocytic, Chronic, B-Cell Cyclophosphamide 3.2617008537 17296974 17802794 18587576 18172266 17658394
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 8.5512560223 17077332
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Emodin 8.5517077332
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 3.8016972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 11.9414633726
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Cyclophosphamide 11.9410373061
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Indomethacin 11.9410785260 15631656 16572323
MESH:D007951 Leukemia, Myeloid arsenic trioxide 3.3119077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 5.6019850784 16968895 17050201 16467208 20471514
MESH:D015470 Leukemia, Myeloid, Acute Indomethacin 5.6018360721
MESH:D015470 Leukemia, Myeloid, Acute trichostatin A 5.6018206229
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 2.8716966277 17649720 16331271 19035177 15622746 16823087 17869043 11161223 15748426 16112521 19225113 16891316 15336539 19642359 17217047 19075265 12679006 11468182 12018890 17712046 16330433 12712474 9834237 17107899 15213294
MESH:D015458 Leukemia, T-Cell arsenic trioxide 3.8716882451
MESH:D007964 Leukocytosis Indomethacin 4.8516537180
MESH:D007969 Leukomalacia, Periventricular Indomethacin 5.2017980183
MESH:D007970 Leukopenia Cyclophosphamide 10.0810052129 11830472
MESH:D007970 Leukopenia Lipopolysaccharides 10.0815821434
MESH:D007984 Leydig Cell Tumor vinclozolin 4.2216417039
MESH:D008064 Lipidoses Tamoxifen 2.7915342952 17567588
MESH:D008101 Liver Abscess, Amebic Indomethacin 5.2011479899
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 13.3017157831 16239168 17334410 16943688 17174718 11408273 16221502 11903743 21278145
MESH:D008103 Liver Cirrhosis Dietary Fats 13.3018296743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 13.3020032147 18407596 18665156 19638242 18522880
MESH:D008103 Liver Cirrhosis Phenobarbital 13.3021047994
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 14.0320821823 18395095 11481614 12609069 17565644 17976157 18472094 12632512 14620537 15959796 17481882 16011737 14512876 15996030 18054572 10355542 12445418 17525996 12649538 16097048 17944888 17721639 17698563 15123356 16136751 18263696 18006644 18187930 15650968 12667390 18317297 17761835 12389079 18166357 15370692 17631135 15925388 16116963 15893842 16033810 17869086 17640975 14724832 12741479 14716496 18418968 16248980 13678700 17714472 18205269 18210741 14716833 12666154 12958196 17823541 15876570 15931870 15057751 18395914 12445421 17805973 18156304 18376398 18339082 16015684 16027843 15338365 18429990 18412020 17766677 18472332 15052691 17922224 16192424 14748882 18705752 16638106 12586293 17557913 18420326 18277467 18279442 12632514 18481824 12898905 17708605 15730626 15818738 12546737 15362042 18251166 17900296 15673190
MESH:D008106 Liver Cirrhosis, Experimental Emodin 14.0315288473
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 14.0314716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Fenofibrate 14.0315474484
MESH:D008106 Liver Cirrhosis, Experimental Indomethacin 14.0318194892
MESH:D008106 Liver Cirrhosis, Experimental Lipopolysaccharides 14.0312878042
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 14.0315474484
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 14.0318564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 14.0312878042
MESH:D008107 Liver Diseases Acetaminophen 10.8119460945 12587719 19784758 11587558 12969438 16611625 19014921 16610002
MESH:D008107 Liver Diseases Carbon Tetrachloride 10.8116246199 15720792 16964402 17285989 15830285
MESH:D008107 Liver Diseases Diethylnitrosamine 10.8117034775
MESH:D008107 Liver Diseases Phenobarbital 10.8119363144
MESH:D008107 Liver Diseases propiconazole 10.8119363144
MESH:D017093 Liver Failure Carbon Tetrachloride 3.6715123358
MESH:D017114 Liver Failure, Acute Acetaminophen 7.9416871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 7.9416899240 14706259
MESH:D008113 Liver Neoplasms arsenic trioxide 29.6014682389
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 29.6019294768
MESH:D008113 Liver Neoplasms Diethylnitrosamine 29.6019638242 20492335 18754104 19090486 19690152 19996281 18644402 20583210 21278145 20501860 19426721 19254457 19294768 19551842 19499222 19642983 18977376 21071580 12112319 20434301 19256749 20118626 9163691 19427195 20452335 18978307 12771043 2422723 19833225 2862719 19812893 18648771 20405173 21167192 20137499 19255062 20101389 16942905 21047994 15885732 10737359 15175105 19850985 19073162
MESH:D008113 Liver Neoplasms Fenofibrate 29.6018978307
MESH:D008113 Liver Neoplasms Phenobarbital 29.6019482888 19812893 8742319 15975961 21047994 19073162
MESH:D008113 Liver Neoplasms pirinixic acid 29.6016377806 20007298 15890375
MESH:D008113 Liver Neoplasms propiconazole 29.6019028983
MESH:D008113 Liver Neoplasms sodium arsenite 29.6016712894 15276417
MESH:D008113 Liver Neoplasms Tamoxifen 29.6016684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 29.6016984957
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 23.2020377131
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 23.2015583823 12014681
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 23.2016267830 18093689 19539802 18544905 19009564 18775883 19126423 18079962 18282651 17942915 21159647 3124819 17854601 18164116 9362446 19004024 17174075 19519916 18253720 18308698 2563599 16842330
MESH:D008114 Liver Neoplasms, Experimental Fenofibrate 23.2018775883 18253720
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 23.2018308698 1399818 6150874 17172636 2563599
MESH:D008114 Liver Neoplasms, Experimental propiconazole 23.2017178689
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 23.2012151625
MESH:D008133 Long QT Syndrome arsenic trioxide 2.9615213294
MESH:D008171 Lung Diseases sodium arsenite 2.8219095001
MESH:D055370 Lung Injury Lipopolysaccharides 3.5221114838
MESH:D008175 Lung Neoplasms arsenic trioxide 9.4411798837 19825857
MESH:D008175 Lung Neoplasms Diethylnitrosamine 9.4420970405 21163286 20512841 6695378
MESH:D008175 Lung Neoplasms Indomethacin 9.4411053908 11497255 16537180
MESH:D008175 Lung Neoplasms sodium arsenite 9.4419931552 17306315 17077188 15276417 16712894
MESH:D008175 Lung Neoplasms Tamoxifen 9.4418625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 9.4419555203 11884234
MESH:D008175 Lung Neoplasms Vehicle Emissions 9.449255578
MESH:D008223 Lymphoma Cyclophosphamide 3.4712854902
MESH:D016393 Lymphoma, B-Cell Cyclophosphamide 4.1316675587
MESH:D008228 Lymphoma, Non-Hodgkin Cyclophosphamide 3.7511911406
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.2619428831
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 8.0111408345 11807958 17203775 16891317
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 8.0111408345 17203775
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 8.0114580682 19196722 11731420 16827153 19196723
MESH:D020149 Manganese Poisoning Estradiol 10.9219453300
MESH:D020149 Manganese Poisoning Tamoxifen 10.9219453300
MESH:D008545 Melanoma sodium arsenite 4.5516487513 19082730
MESH:D008545 Melanoma Tamoxifen 4.5519393235 12393984
MESH:D008545 Melanoma trichostatin A 4.5516505122
MESH:D018328 Melanoma, Amelanotic Tamoxifen 3.6715990972
MESH:D008546 Melanoma, Experimental Acetaminophen 9.1819513568
MESH:D008546 Melanoma, Experimental Cyclophosphamide 9.1816388313
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.2716801185
MESH:D008881 Migraine Disorders Indomethacin 3.3111903285
MESH:D018200 Mixed Tumor, Mullerian Raloxifene 5.0415863610
MESH:D009062 Mouth Neoplasms Indomethacin 3.6012636206
MESH:D009101 Multiple Myeloma arsenic trioxide 14.3619417148 15949261 14977855 19549372 11468182
MESH:D009101 Multiple Myeloma Raloxifene 14.3616497877
MESH:D009101 Multiple Myeloma S-(dimethylarsino)-glutathione 14.3619417148
MESH:D009101 Multiple Myeloma trichostatin A 14.3618172295
MESH:D009135 Muscular Diseases pirinixic acid 3.0116239165
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.1518349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 2.8416105982 16882451
MESH:D009203 Myocardial Infarction pirinixic acid 1.9219151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.6112213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 6.9416810080
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 6.9416411023
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 3.9717484760
MESH:D009232 Myxoma Raloxifene 5.0416343187
MESH:D009336 Necrosis 2,4-dinitrotoluene 3.3518551238
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.4816624393
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 8.223581430 9029167
MESH:D009362 Neoplasm Metastasis Indomethacin 8.2211239499 16537180 11053908
MESH:D009362 Neoplasm Metastasis Tamoxifen 8.2219393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.3319410462
MESH:D009369 Neoplasms Cyclophosphamide 6.7518854779
MESH:D009369 Neoplasms pirinixic acid 6.7517405874
MESH:D009369 Neoplasms sodium arsenite 6.7511559025
MESH:D009374 Neoplasms, Experimental Indomethacin 7.6415625704 10663608
MESH:D009374 Neoplasms, Experimental sodium arsenite 7.6420056578
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.4819200415 19189210 19196722
MESH:D009389 Neovascularization, Pathologic Estradiol 3.2317289903
MESH:D009402 Nephrosis, Lipoid Cyclosporine 3.9217954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 2.8618481113 19348381
MESH:D009410 Nerve Degeneration Paraquat 3.3216893418
MESH:D009421 Nervous System Malformations Estradiol 7.8611399458 16427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 7.8614600291
MESH:D009436 Neural Tube Defects arsenic trioxide 6.1910525206
MESH:D009436 Neural Tube Defects sodium arsenite 6.1912854658
MESH:D009447 Neuroblastoma Cyclophosphamide 3.3615176712 8761367 16115947
MESH:D019636 Neurodegenerative Diseases Acetaminophen 11.6718514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 11.6720387270
MESH:D019636 Neurodegenerative Diseases Indomethacin 11.6712349958
MESH:D017599 Neuroectodermal Tumors Cyclophosphamide 4.3812837982 8761367
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.6020387270
MESH:D009503 Neutropenia Cyclophosphamide 3.868291058
MESH:D009765 Obesity Dietary Fats 3.9317217161 16723640 21332399 18457598 19632207 11836018 18674790 20518802 20132043
MESH:D009765 Obesity pirinixic acid 3.9320558911
MESH:D007752 Obstetric Labor, Premature Indomethacin 4.656374098
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 7.6712819281 16049721
MESH:D009784 Occupational Diseases 4-amino-2,6-dinitrotoluene 7.6714694615
MESH:D009845 Oligospermia Cyclophosphamide 4.2116517039
MESH:D010003 Osteoarthritis Indomethacin 3.357009135
MESH:D010018 Osteomalacia Phenobarbital 3.8617016548
MESH:D010024 Osteoporosis Raloxifene 3.0717882678 19059307 15775268
MESH:D015663 Osteoporosis, Postmenopausal Raloxifene 3.7617823083 17893378 15758505 15579764
MESH:D010051 Ovarian Neoplasms arsenic trioxide 12.9812452020 19769630 16624393
MESH:D010051 Ovarian Neoplasms Estradiol 12.9819401270
MESH:D010051 Ovarian Neoplasms Progesterone 12.9816525653 17393432
MESH:D010051 Ovarian Neoplasms sodium arsenite 12.9815276417 17306315
MESH:D010051 Ovarian Neoplasms trichostatin A 12.9819331143
MESH:D010146 Pain Acetaminophen 8.9916870215
MESH:D010146 Pain Cyclophosphamide 8.9918093676 12161096
MESH:D010146 Pain Indomethacin 8.9913679232 17440234 3291741 17627676
MESH:D010149 Pain, Postoperative Indomethacin 4.1618702446 12538197
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 14.1015580305
MESH:D010190 Pancreatic Neoplasms Cyclophosphamide 14.1011332152
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 14.1016540662
MESH:D010190 Pancreatic Neoplasms Phenobarbital 14.1016965848
MESH:D010190 Pancreatic Neoplasms trichostatin A 14.1019294695
MESH:D010195 Pancreatitis Indomethacin 3.4615028970 17883296
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.2211578682
MESH:D010212 Papilloma Hydrogen Peroxide 3.6012065085
MESH:D010235 Paraganglioma arsenic trioxide 3.6919927285
MESH:D010257 Paraneoplastic Syndromes Indomethacin 5.2016537180
MESH:D010300 Parkinson Disease Paraquat 2.6111445065 15824117 12911755 11181820 11124998 15451049 16140633 16510128
MESH:D010302 Parkinson Disease, Secondary Paraquat 3.9416190885
MESH:D020734 Parkinsonian Disorders Indomethacin 3.6812349958
MESH:D051302 Paroxysmal Hemicrania Indomethacin 5.2011903285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.7312520081
MESH:D010437 Peptic Ulcer Indomethacin 4.6411148446
MESH:D010518 Periodontitis Indomethacin 4.4017225004
MESH:D016491 Peripheral Vascular Diseases Cadmium 4.8715687053
MESH:D011014 Pneumonia Lipopolysaccharides 9.4412224865 11605937
MESH:D011014 Pneumonia Paraquat 9.4412504350
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.0818163543
MESH:D011230 Precancerous Conditions Cyclosporine 12.7912371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 12.792563599
MESH:D011230 Precancerous Conditions Phenobarbital 12.792563599
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Cyclophosphamide 3.5021297632
MESH:D047928 Premature Birth Indomethacin 4.6317000239
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 7.8111896295 11222880 11118676 11399792
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 7.8118042343 18220299 19015723
MESH:D055728 Primary Myelofibrosis trichostatin A 4.7517616702
MESH:D011469 Prostatic Diseases vinclozolin 4.4318220299
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.4320887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.3019131511
MESH:D011471 Prostatic Neoplasms Cadmium 2.3017075824
MESH:D011471 Prostatic Neoplasms Cyclophosphamide 2.3017136230
MESH:D011471 Prostatic Neoplasms Estradiol 2.3016740699
MESH:D011471 Prostatic Neoplasms Raloxifene 2.3015731164 16536755 16220300
MESH:D011471 Prostatic Neoplasms sodium arsenite 2.3016039940
MESH:D011471 Prostatic Neoplasms Tamoxifen 2.3015067354
MESH:D011471 Prostatic Neoplasms trichostatin A 2.3019789329 18798265
MESH:D011472 Prostatitis vinclozolin 4.4318629315
MESH:D011507 Proteinuria Indomethacin 3.7011849393
MESH:D011537 Pruritus Ethinyl Estradiol 2.8115861022 16919318
MESH:D019310 Pseudolymphoma Phenobarbital 3.9812752131
MESH:D011565 Psoriasis Cyclosporine 2.0316882103
MESH:D011658 Pulmonary Fibrosis Cyclophosphamide 5.2716636934
MESH:D011658 Pulmonary Fibrosis Paraquat 5.2717997886 16324872
MESH:D011693 Purpura Raloxifene 5.0415770314
MESH:D015427 Reperfusion Injury pirinixic acid 2.1219058328
MESH:D012128 Respiratory Distress Syndrome, Adult Paraquat 3.4411700416
MESH:D012130 Respiratory Hypersensitivity Lipopolysaccharides 3.3910835634
MESH:D012135 Respiratory Sounds Paraquat 8.5111874814
MESH:D012135 Respiratory Sounds Vehicle Emissions 8.5118950799
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.3518990726
MESH:D012162 Retinal Degeneration Paraquat 3.4816458197
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.6618045962
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 3.4816646077
MESH:D012595 Scleroderma, Systemic Cyclophosphamide 4.3516636934
MESH:D012640 Seizures 2,4-dinitrotoluene 4.7618551238
MESH:D012640 Seizures Phenobarbital 4.7616876388 3137016 4039156 11442880
MESH:D003294 Seizures, Febrile Phenobarbital 4.316407741
MESH:D012772 Shock, Septic endotoxin, Escherichia coli 5.1318063050
MESH:D012878 Skin Neoplasms Hydrogen Peroxide 11.4212065085
MESH:D012878 Skin Neoplasms sodium arsenite 11.4219524636 18572023
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 11.428532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 11.4216192470
MESH:D013088 Spermatocele Ethinyl Estradiol 9.8416709447
MESH:D013088 Spermatocele Tamoxifen 9.8416709447
OMIM:102530 SPERMATOGENIC FAILURE 6 Cyclophosphamide 5.0016517039
MESH:D013119 Spinal Cord Injuries Progesterone 9.1815862959 16503802
MESH:D013119 Spinal Cord Injuries Tamoxifen 9.1819457130
MESH:D016135 Spinal Dysraphism sodium arsenite 3.4012854658
MESH:D013272 Stomach Diseases Indomethacin 3.9118545984 10486359 15038085 10215738 17638125 10192188 16113693 17207306 16184426 17160473 18209964 15472012 16280098
MESH:D013274 Stomach Neoplasms arsenic trioxide 3.1017007042
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 3.1018456281
MESH:D013274 Stomach Neoplasms Indomethacin 3.1015609394
MESH:D013276 Stomach Ulcer Indomethacin 3.1515138204 16755016 17918041 11145282 15104355 17627676 16397915 17135157 10878458 10750652 16150113 12500499 17895592 18431645 10423059 16252198 12077510 18087811 1323529 16631530 18543354 12467913 18299717 11523592 14567935 18193104 11595431 18181030 17657623 18726076 16934674 12498302 17654042 15255614 12787963 11906479 17977527 11729361 16169175 11595415 18237397 18209962
MESH:D020521 Stroke Raloxifene 3.4216837676
MESH:D015173 Supratentorial Neoplasms Cyclophosphamide 4.5512837982
MESH:D013733 Testicular Diseases pyrazole 4.316499806
MESH:D013921 Thrombocytopenia Lipopolysaccharides 3.7215821434
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.1511994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.7315669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.3812697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 13.9319014326
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 13.937505956
MESH:D013964 Thyroid Neoplasms Indomethacin 13.9318791128 11352223 14736730
MESH:D013964 Thyroid Neoplasms Phenobarbital 13.931399818
MESH:D013978 Tibial Fractures Estradiol 11.9919048282
MESH:D013978 Tibial Fractures Raloxifene 11.9919048282
MESH:D016171 Torsades de Pointes arsenic trioxide 3.4615213294
MESH:D014456 Ulcer Indomethacin 4.3917380554 10574470
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 20.6816049721
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 20.6812973940 20435036 12845720 11780464
MESH:D001749 Urinary Bladder Neoplasms Cyclophosphamide 20.6814692829
MESH:D001749 Urinary Bladder Neoplasms Raloxifene 20.6817572228
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 20.6811723127 17306315 16712894 16452187
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 20.688653321 17572228 16712894
MESH:D001749 Urinary Bladder Neoplasms Vehicle Emissions 20.6811144890
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 3.8110091137
MESH:D014581 Urticaria Acetaminophen 2.5110982225
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 3.3311813266
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 2.8214692618
MESH:D014605 Uveitis Cyclosporine 3.471336536
MESH:D014652 Vascular Diseases sodium arsenite 3.9217056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.0812125929
MESH:D054556 Venous Thromboembolism Raloxifene 4.6916837676
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.0814671159 15869587
MESH:D014839 Vomiting Indomethacin 4.2311897121
MESH:D014846 Vulvar Neoplasms Raloxifene 5.0416343187
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.7315886252
MESH:D015430 Weight Gain Dietary Fats 3.3116723640
MESH:D014985 Xerophthalmia Cyclosporine 3.9217120751
Pathway ID Pathway Name
KEGG:04141 Protein processing in endoplasmic reticulum
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA27412
    • No data
    No data
    Releated drug ID Related drug Name
    PA449177cytarabine
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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