Annotation Detail for PPM1J
Basic Information
Top
| Gene Symbol: | PPM1J ( DKFZp434P1514,FLJ35951,MGC19531,MGC90149,PP2CZ,PP2Czeta,PPP2CZ ) |
|---|
| Gene Full Name: | protein phosphatase, Mg2+/Mn2+ dependent, 1J |
|---|
| Band: | 1p13.2 |
|---|
| Quick Links | Entrez ID:333926; OMIM: 609957; Uniprot ID:PPM1J_HUMAN; ENSEMBL ID: ENSG00000155367; HGNC ID: 20785 |
|---|
| Relate to Another Database: |
SFARIGene;
denovo-db |
| Pathway ID | Pathway Name |
|---|
| 200101 | Direct p53 effectors |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D012643 |
Selenium |
Selenium results in increased expression of PPM1J mRNA | increases expression | 19244175
|
| D014635 |
Valproic Acid |
Valproic Acid results in increased expression of PPM1J mRNA | increases expression | 19101580
|
| D014810 |
Vitamin E |
Vitamin E results in increased expression of PPM1J mRNA | increases expression | 19244175
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000014 |
Abnormalities, Drug-Induced |
|
Valproic Acid |
4.23 | 8875741 |
| MESH:D000015 |
Abnormalities, Multiple |
|
Valproic Acid |
4.41 | 19490988 |
| MESH:D000550 |
Amblyopia |
|
Valproic Acid |
6.10 | 17688650 |
| MESH:D001008 |
Anxiety Disorders |
|
Valproic Acid |
3.94 | 17497229 |
| MESH:D001321 |
Autistic Disorder |
|
Valproic Acid |
1.98 | 19232924 18316065 18396377 17507914 18940202 20603192 18985861 15238991 17688650 18177632 18558336 16609825 18775368 19460635 17157402 |
| MESH:D001714 |
Bipolar Disorder |
|
Valproic Acid |
3.26 | 17594078 20046352 |
| MESH:D001848 |
Bone Diseases, Developmental |
|
Valproic Acid |
3.66 | 8888407 |
| MESH:D002252 |
Carbon Tetrachloride Poisoning |
|
Vitamin E |
4.58 | 16050911 |
| MESH:D002659 |
Child Development Disorders, Pervasive |
|
Valproic Acid |
2.83 | 20734317 |
| MESH:D003092 |
Colitis |
|
Selenium |
4.43 | 17936198 |
| MESH:D019465 |
Craniofacial Abnormalities |
|
Valproic Acid |
2.81 | 17688650 16575769 8888407 |
| MESH:D019465 |
Craniofacial Abnormalities |
|
Vitamin E |
2.81 | 19769572 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Selenium |
4.34 | 15131321 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Valproic Acid |
4.34 | 19641884 1733752 |
| MESH:D004421 |
Dystonia |
|
Valproic Acid |
4.58 | 1851702 |
| MESH:C538011 |
Eales disease |
|
Vitamin E |
5.57 | 9068938 |
| MESH:D004831 |
Epilepsies, Myoclonic |
|
Valproic Acid |
4.81 | 17275665 3659116 |
| MESH:D004828 |
Epilepsies, Partial |
|
Valproic Acid |
4.78 | 3922381 16628512 |
| MESH:D004827 |
Epilepsy |
|
Valproic Acid |
3.12 | 20417680 18234410 |
| MESH:D004832 |
Epilepsy, Absence |
|
Valproic Acid |
4.00 | 6254150 7562514 6426943 |
| MESH:D017029 |
Epilepsy, Complex Partial |
|
Valproic Acid |
4.95 | 7750514 |
| MESH:D004830 |
Epilepsy, Tonic-Clonic |
|
Valproic Acid |
4.81 | 3659116 |
| MESH:D005234 |
Fatty Liver |
|
Valproic Acid |
3.78 | 19224547 14986274 |
| MESH:D005315 |
Fetal Diseases |
|
Valproic Acid |
5.75 | 16575769 |
| MESH:D005317 |
Fetal Growth Retardation |
|
Valproic Acid |
4.71 | 18558336 8888407 |
| MESH:D006330 |
Heart Defects, Congenital |
|
Vitamin E |
3.18 | 16080930 |
| MESH:D006333 |
Heart Failure |
|
Selenium |
3.32 | 17162251 |
| MESH:D006548 |
Hernia, Diaphragmatic |
|
Vitamin E |
2.82 | 16490937 16863852 |
| MESH:D019584 |
Hot Flashes |
|
Vitamin E |
4.84 | 14716179 |
| MESH:D006849 |
Hydrocephalus |
|
Valproic Acid |
5.61 | 17688650 |
| MESH:D007251 |
Influenza, Human |
|
Selenium |
14.07 | 16624496 |
| MESH:D007251 |
Influenza, Human |
|
Vitamin E |
14.07 | 16624496 |
| MESH:D007674 |
Kidney Diseases |
|
Vitamin E |
3.03 | 12488133 |
| MESH:D007676 |
Kidney Failure, Chronic |
|
Selenium |
4.37 | 16518626 |
| MESH:D015470 |
Leukemia, Myeloid, Acute |
|
Valproic Acid |
2.20 | 17596541 16294345 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
Vitamin E |
1.91 | 16169303 |
| MESH:D008171 |
Lung Diseases |
|
Vitamin E |
3.45 | 16863852 |
| MESH:D017563 |
Lung Diseases, Interstitial |
|
Valproic Acid |
5.13 | 17228818 |
| MESH:D008175 |
Lung Neoplasms |
|
Vitamin E |
1.90 | 11062179 |
| MESH:D008325 |
Mammary Neoplasms, Experimental |
|
Selenium |
3.02 | 15318939 |
| MESH:D008654 |
Mesothelioma |
|
Selenium |
2.93 | 15107826 |
| MESH:D008881 |
Migraine Disorders |
|
Valproic Acid |
3.50 | 18803445 18765137 |
| MESH:D009139 |
Musculoskeletal Abnormalities |
|
Valproic Acid |
4.51 | 8888407 |
| MESH:D009190 |
Myelodysplastic Syndromes |
|
Valproic Acid |
3.37 | 17596541 |
| MESH:D009436 |
Neural Tube Defects |
|
Valproic Acid |
3.39 | 16359493 8888407 |
| MESH:D010954 |
Plasmacytoma |
|
Selenium |
5.76 | 15087411 |
| MESH:D011297 |
Prenatal Exposure Delayed Effects |
|
Valproic Acid |
4.57 | 20603192 |
| MESH:D011471 |
Prostatic Neoplasms |
|
Vitamin E |
3.24 | 15084515 |
| MESH:D019310 |
Pseudolymphoma |
|
Valproic Acid |
5.41 | 11422049 12752131 |
| MESH:D012208 |
Rhabdomyosarcoma |
|
Valproic Acid |
4.70 | 19155313 |
| MESH:D012559 |
Schizophrenia |
|
Valproic Acid |
2.11 | 15737665 19110320 |
| MESH:D012640 |
Seizures |
|
Valproic Acid |
3.02 | 11738929 1511512 16876388 15475178 14763951 17978042 11044598 3137016 |
| MESH:D012871 |
Skin Diseases |
|
Vitamin E |
2.52 | 18709164 |
| MESH:D016135 |
Spinal Dysraphism |
|
Valproic Acid |
4.13 | 19490988 |
| MESH:D013226 |
Status Epilepticus |
|
Valproic Acid |
5.41 | 12833885 |
| MESH:D020521 |
Stroke |
|
Vitamin E |
3.88 | 16517955 |
| MESH:D014178 |
Translocation, Genetic |
|
Valproic Acid |
6.10 | 17262798 |
| MESH:D020194 |
Unverricht-Lundborg Syndrome |
|
Valproic Acid |
5.26 | 3119515 |
| MESH:D014564 |
Urogenital Abnormalities |
|
Valproic Acid |
5.30 | 8888407 |
Pharmacogenomics Knowledge Base