AutismKB 2.0

Annotation Detail for HTR7


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Basic Information Top
Gene Symbol:HTR7 ( 5-HT7 )
Gene Full Name: 5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled)
Band: 10q23.31
Quick LinksEntrez ID:3363; OMIM: 182137; Uniprot ID:5HT7R_HUMAN; ENSEMBL ID: ENSG00000148680; HGNC ID: 5302
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04080Neuroactive ligand-receptor interaction
hsa04020Calcium signaling pathway
Pathway IDPathway Name
Signaling by GPCR
No data
Pathway IDPathway Name
P00026Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1943Adenocarcinoma
2091Hypertension
2069Schizophrenia
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C047087 5-carboxamidotryptamine [5-carboxamidotryptamine binds to and results in increased activity of HTR7 protein] which results in increased abundance of Cyclic AMPaffects binding|increases abundance|increases activity 14578406
C047087 5-carboxamidotryptamine [Clozapine binds to and results in decreased activity of HTR7 protein] inhibits the reaction [5-carboxamidotryptamine results in increased abundance of Cyclic AMP]affects binding|decreases activity|decreases reaction|increases abundance 14578406
C047087 5-carboxamidotryptamine [CQ 32085 binds to and results in decreased activity of HTR7 protein] inhibits the reaction [5-carboxamidotryptamine results in increased abundance of Cyclic AMP]affects binding|decreases activity|decreases reaction|increases abundance 14578406
C047087 5-carboxamidotryptamine [Ketanserin binds to and results in decreased activity of HTR7 protein] inhibits the reaction [5-carboxamidotryptamine results in increased abundance of Cyclic AMP]affects binding|decreases activity|decreases reaction|increases abundance 14578406
C047087 5-carboxamidotryptamine [MDL 100907 binds to and results in decreased activity of HTR7 protein] inhibits the reaction [5-carboxamidotryptamine results in increased abundance of Cyclic AMP]affects binding|decreases activity|decreases reaction|increases abundance 14578406
C047087 5-carboxamidotryptamine [Metergoline binds to and results in decreased activity of HTR7 protein] inhibits the reaction [5-carboxamidotryptamine results in increased abundance of Cyclic AMP]affects binding|decreases activity|decreases reaction|increases abundance 14578406
C047087 5-carboxamidotryptamine [Mianserin binds to and results in decreased activity of HTR7 protein] inhibits the reaction [5-carboxamidotryptamine results in increased abundance of Cyclic AMP]affects binding|decreases activity|decreases reaction|increases abundance 14578406
C047087 5-carboxamidotryptamine [Ritanserin binds to and results in decreased activity of HTR7 protein] inhibits the reaction [5-carboxamidotryptamine results in increased abundance of Cyclic AMP]affects binding|decreases activity|decreases reaction|increases abundance 14578406
C047087 5-carboxamidotryptamine [SB 258719 binds to and results in decreased activity of HTR7 protein] inhibits the reaction [5-carboxamidotryptamine results in increased abundance of Cyclic AMP]affects binding|decreases activity|decreases reaction|increases abundance 14578406
C047087 5-carboxamidotryptamine [Spiperone binds to and results in decreased activity of HTR7 protein] inhibits the reaction [5-carboxamidotryptamine results in increased abundance of Cyclic AMP]affects binding|decreases activity|decreases reaction|increases abundance 14578406
D000242 Cyclic AMP [5-carboxamidotryptamine binds to and results in increased activity of HTR7 protein] which results in increased abundance of Cyclic AMPaffects binding|increases abundance|increases activity 14578406
D000242 Cyclic AMP [5-Methoxytryptamine binds to and results in increased activity of HTR7 protein] which results in increased abundance of Cyclic AMPaffects binding|increases abundance|increases activity 14578406
D000242 Cyclic AMP [Clozapine binds to and results in decreased activity of HTR7 protein] inhibits the reaction [5-carboxamidotryptamine results in increased abundance of Cyclic AMP]affects binding|decreases activity|decreases reaction|increases abundance 14578406
D000242 Cyclic AMP [CQ 32085 binds to and results in decreased activity of HTR7 protein] inhibits the reaction [5-carboxamidotryptamine results in increased abundance of Cyclic AMP]affects binding|decreases activity|decreases reaction|increases abundance 14578406
D000242 Cyclic AMP [Ketanserin binds to and results in decreased activity of HTR7 protein] inhibits the reaction [5-carboxamidotryptamine results in increased abundance of Cyclic AMP]affects binding|decreases activity|decreases reaction|increases abundance 14578406
D000242 Cyclic AMP [MDL 100907 binds to and results in decreased activity of HTR7 protein] inhibits the reaction [5-carboxamidotryptamine results in increased abundance of Cyclic AMP]affects binding|decreases activity|decreases reaction|increases abundance 14578406
D000242 Cyclic AMP [Metergoline binds to and results in decreased activity of HTR7 protein] inhibits the reaction [5-carboxamidotryptamine results in increased abundance of Cyclic AMP]affects binding|decreases activity|decreases reaction|increases abundance 14578406
D000242 Cyclic AMP [Methiothepin binds to and results in decreased activity of HTR7 protein] which results in decreased abundance of Cyclic AMPaffects binding|decreases abundance|decreases activity 14578406
D000242 Cyclic AMP [Methoxydimethyltryptamines binds to and results in increased activity of HTR7 protein] which results in increased abundance of Cyclic AMPaffects binding|increases abundance|increases activity 14578406
D000242 Cyclic AMP [Mianserin binds to and results in decreased activity of HTR7 protein] inhibits the reaction [5-carboxamidotryptamine results in increased abundance of Cyclic AMP]affects binding|decreases activity|decreases reaction|increases abundance 14578406
D000242 Cyclic AMP [Ritanserin binds to and results in decreased activity of HTR7 protein] inhibits the reaction [5-carboxamidotryptamine results in increased abundance of Cyclic AMP]affects binding|decreases activity|decreases reaction|increases abundance 14578406
D000242 Cyclic AMP [SB 258719 binds to and results in decreased activity of HTR7 protein] inhibits the reaction [5-carboxamidotryptamine results in increased abundance of Cyclic AMP]affects binding|decreases activity|decreases reaction|increases abundance 14578406
D000242 Cyclic AMP [Serotonin binds to and results in increased activity of HTR7 protein] which results in increased abundance of Cyclic AMPaffects binding|increases abundance|increases activity 14578406
D000242 Cyclic AMP [Spiperone binds to and results in decreased activity of HTR7 protein] inhibits the reaction [5-carboxamidotryptamine results in increased abundance of Cyclic AMP]affects binding|decreases activity|decreases reaction|increases abundance 14578406
D000643 Ammonium Chloride Ammonium Chloride affects the expression of HTR7 mRNAaffects expression 16483693
D002118 Calcium HTR7 protein promotes the reaction [[Freund's Adjuvant results in increased activity of TRPV1 protein] which results in increased transport of Calcium]increases activity|increases reaction|increases transport 16901936
D004390 Chlorpyrifos Chlorpyrifos affects the expression of HTR7 mRNAaffects expression 18835401
D003024 Clozapine [Clozapine binds to and results in decreased activity of HTR7 protein] inhibits the reaction [5-carboxamidotryptamine results in increased abundance of Cyclic AMP]affects binding|decreases activity|decreases reaction|increases abundance 14578406
C031649 CQ 32085 [CQ 32085 binds to and results in decreased activity of HTR7 protein] inhibits the reaction [5-carboxamidotryptamine results in increased abundance of Cyclic AMP]affects binding|decreases activity|decreases reaction|increases abundance 14578406
D003976 Diazinon Diazinon affects the expression of HTR7 mRNAaffects expression 17452286
D005419 Flavonoids Flavonoids results in decreased expression of HTR7 mRNAdecreases expression 18035473
D005472 Fluorouracil Fluorouracil affects the expression of HTR7 mRNAaffects expression 16584549
D005620 Freund's Adjuvant Freund's Adjuvant results in increased expression of HTR7 mRNAincreases expression 16901936
D005620 Freund's Adjuvant HTR7 protein promotes the reaction [[Freund's Adjuvant results in increased activity of TRPV1 protein] which results in increased transport of Calcium]increases activity|increases reaction|increases transport 16901936
D012701 Serotonin [Serotonin binds to and results in increased activity of HTR7 protein] which results in increased abundance of Cyclic AMPaffects binding|increases abundance|increases activity 14578406
D007650 Ketanserin [Ketanserin binds to and results in decreased activity of HTR7 protein] inhibits the reaction [5-carboxamidotryptamine results in increased abundance of Cyclic AMP]affects binding|decreases activity|decreases reaction|increases abundance 14578406
D008070 Lipopolysaccharides HTR7 protein inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]decreases reaction|increases secretion 15802305
D008070 Lipopolysaccharides HTR7 protein promotes the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]increases reaction|increases secretion 15802305
D008070 Lipopolysaccharides HTR7 protein promotes the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]increases reaction|increases secretion 15802305
D008070 Lipopolysaccharides HTR7 protein promotes the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]increases reaction|increases secretion 15802305
D008070 Lipopolysaccharides HTR7 protein promotes the reaction [Lipopolysaccharides results in increased secretion of IL8 protein]increases reaction|increases secretion 15802305
D008070 Lipopolysaccharides Lipopolysaccharides results in increased expression of HTR7 mRNAincreases expression 12057914
C079049 MDL 100907 [MDL 100907 binds to and results in decreased activity of HTR7 protein] inhibits the reaction [5-carboxamidotryptamine results in increased abundance of Cyclic AMP]affects binding|decreases activity|decreases reaction|increases abundance 14578406
D008628 Mercury Mercury results in increased expression of HTR7 mRNAincreases expression 16823088
D008711 Metergoline [Metergoline binds to and results in decreased activity of HTR7 protein] inhibits the reaction [5-carboxamidotryptamine results in increased abundance of Cyclic AMP]affects binding|decreases activity|decreases reaction|increases abundance 14578406
D008719 Methiothepin [Methiothepin binds to and results in decreased activity of HTR7 protein] which results in decreased abundance of Cyclic AMPaffects binding|decreases abundance|decreases activity 14578406
D008732 Methoxydimethyltryptamines [Methoxydimethyltryptamines binds to and results in increased activity of HTR7 protein] which results in increased abundance of Cyclic AMPaffects binding|increases abundance|increases activity 14578406
D008735 5-Methoxytryptamine [5-Methoxytryptamine binds to and results in increased activity of HTR7 protein] which results in increased abundance of Cyclic AMPaffects binding|increases abundance|increases activity 14578406
D008803 Mianserin [Mianserin binds to and results in decreased activity of HTR7 protein] inhibits the reaction [5-carboxamidotryptamine results in increased abundance of Cyclic AMP]affects binding|decreases activity|decreases reaction|increases abundance 14578406
D017371 8-Hydroxy-2-(di-n-propylamino)tetralin 8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in increased activity of HTR7 proteinaffects binding|increases activity 15802305
D016713 Ritanserin [Ritanserin binds to and results in decreased activity of HTR7 protein] inhibits the reaction [5-carboxamidotryptamine results in increased abundance of Cyclic AMP]affects binding|decreases activity|decreases reaction|increases abundance 14578406
C111309 SB 258719 [SB 258719 binds to and results in decreased activity of HTR7 protein] inhibits the reaction [5-carboxamidotryptamine results in increased abundance of Cyclic AMP]affects binding|decreases activity|decreases reaction|increases abundance 14578406
D013134 Spiperone [Spiperone binds to and results in decreased activity of HTR7 protein] inhibits the reaction [5-carboxamidotryptamine results in increased abundance of Cyclic AMP]affects binding|decreases activity|decreases reaction|increases abundance 14578406
D013629 Tamoxifen Tamoxifen results in decreased expression of HTR7 mRNAdecreases expression 15590111
D014415 Tunicamycin Tunicamycin results in decreased expression of HTR7 mRNAdecreases expression 17127020
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.3214745880
MESH:D000138 Acidosis Ammonium Chloride 3.3318287403
MESH:D055371 Acute Lung Injury Lipopolysaccharides 3.8211850527 18653653
MESH:D000230 Adenocarcinoma Fluorouracil 2.3717638652
MESH:D000380 Agranulocytosis Clozapine 4.8316160616 14617031 12649775
MESH:D000382 Agricultural Workers' Diseases Chlorpyrifos 8.4111874814 16611668 17119214
MESH:D000382 Agricultural Workers' Diseases Diazinon 8.4116487989
MESH:D000740 Anemia Fluorouracil 3.5117963324 16511603 15504547
MESH:D001321 Autistic Disorder Mercury 2.8917497416
MESH:D001321 Autistic Disorder Serotonin 2.8917157402 18062943 18361446 15132762 19221690 18405062 8570775
MESH:D001327 Autoimmune Diseases Mercury 4.6516634805
MESH:D001862 Bone Resorption Freund's Adjuvant 4.9216769263
MESH:D001919 Bradycardia Serotonin 5.258112388
MESH:D001928 Brain Diseases, Metabolic 5-Methoxytryptamine 7.5718062943
MESH:D001943 Breast Neoplasms Fluorouracil 2.2816557594 19217205 18357371 15136595 16595493 16110121 18608205
MESH:D001943 Breast Neoplasms Tamoxifen 2.2819289846 18815881 18997820 19011961 20065188 17893378 18821012 19221464 19066611 19084267 18425577 19189212 17242785 18629630 16818667 19155303 20005174 15565566 16873071 19142967 21138602 15668708 20390343 16202921 19059307 19115204 19103187 20544844 21152245 18351453 17261762 11161223 19200415 18855134 17440819 20135344 19244106 19189210 19487384 17049068 19288272 16273361 19410462 20859285 18984771
MESH:D002276 Carcinoid Tumor Fluorouracil 4.4416051944
MESH:D002277 Carcinoma Fluorouracil 3.3917121937
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.2819066611
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 2.9916332177 18930000 17045692 16799960 17088986 17971768
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 2.9916924424
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 2.9118695887
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 2.4316280240 16757204 17066447 18986760
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.4217572228
MESH:D002311 Cardiomyopathy, Dilated Mercury 3.3710334427
MESH:D002659 Child Development Disorders, Pervasive Serotonin 4.0821254450
MESH:D021081 Chronobiology Disorders Serotonin 6.4617157402
MESH:D003072 Cognition Disorders Clozapine 4.7417123785
MESH:D003110 Colonic Neoplasms Fluorouracil 2.2017018589 17725105 17172411 16510598 17287894 15001691 17016597 18772588 16340194 17169374
MESH:D015179 Colorectal Neoplasms Fluorouracil 2.0015289873 20501625 16391804 16524972 17094418 17454858 18448328 18509181 18949393 16303861 17016601 18802399 18288408 16331619 16282729 17695437 14970324 17401013 17255274 18383874 17594712 15148649
MESH:D019465 Craniofacial Abnormalities Mianserin 4.3610978843
MESH:D019465 Craniofacial Abnormalities Ritanserin 4.3614991402 10978843
MESH:D007644 Darier Disease Fluorouracil 4.5616733453
MESH:D003711 Demyelinating Diseases Tamoxifen 4.1419031437
MESH:D003866 Depressive Disorder Mianserin 5.4318083778
MESH:D017449 Dermatitis, Allergic Contact Mercury 3.5816823706
MESH:D003924 Diabetes Mellitus, Type 2 Clozapine 2.9216402076
MESH:D003928 Diabetic Nephropathies Tamoxifen 3.2919279558
MESH:D003967 Diarrhea Serotonin 4.5510446763 11488427 8112388
MESH:D006970 Disorders of Excessive Somnolence Clozapine 5.3215331141
MESH:D004409 Dyskinesia, Drug-Induced 8-Hydroxy-2-(di-n-propylamino)tetralin 6.2315893579
MESH:D050171 Dyslipidemias Clozapine 4.0216402076
MESH:D004417 Dyspnea Diazinon 4.5716487989
MESH:D004487 Edema Serotonin 4.2818841975
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 3.3219031437
MESH:D016889 Endometrial Neoplasms Tamoxifen 2.9017893378 19155303 16202921 20544844
MESH:D019446 Endotoxemia Lipopolysaccharides 4.1717637181 15328337 15821434
MESH:D004938 Esophageal Neoplasms Fluorouracil 2.3916481741 15173087 16785472 16337965 17638652
MESH:D005234 Fatty Liver Tamoxifen 2.9614986274 19224547
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.1016709447
MESH:D005334 Fever Lipopolysaccharides 3.829205823 11852909
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.3014745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 3.9519069698
MESH:D005910 Glioma Fluorouracil 2.7816145905
MESH:D006258 Head and Neck Neoplasms Fluorouracil 3.2315102660 15162350 18337622
MESH:D006330 Heart Defects, Congenital Ritanserin 5.1914991402
MESH:D018883 Heat Stroke Ketanserin 6.9416205318
MESH:D006463 Hemolytic-Uremic Syndrome Lipopolysaccharides 4.1916366002
MESH:D006505 Hepatitis Diazinon 4.3616487989
MESH:D006930 Hyperalgesia Freund's Adjuvant 4.5016769263
MESH:D006948 Hyperkinesis Clozapine 4.6816046005
MESH:D007248 Infertility, Male Diazinon 3.6712948887 16466525
MESH:D007249 Inflammation Flavonoids 11.1017296493
MESH:D007249 Inflammation Freund's Adjuvant 11.1016793879
MESH:D007249 Inflammation Lipopolysaccharides 11.109205823 12878042 17963957 17237260 17255318
MESH:D007249 Inflammation Tamoxifen 11.1019457130
MESH:D019189 Iron Metabolism Disorders Lipopolysaccharides 4.4217255318
MESH:D007674 Kidney Diseases Mercury 3.4317934191
MESH:D007680 Kidney Neoplasms Fluorouracil 6.9016985049
MESH:D007680 Kidney Neoplasms Tamoxifen 6.9018625569
MESH:D007683 Kidney Tubular Necrosis, Acute Calcium 4.8116316344
MESH:D007970 Leukopenia Lipopolysaccharides 4.4715821434
MESH:D008064 Lipidoses Clozapine 7.5417567588
MESH:D008064 Lipidoses Tamoxifen 7.5417567588 15342952
MESH:D008106 Liver Cirrhosis, Experimental Lipopolysaccharides 2.5812878042
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 2.5818564211
MESH:D008107 Liver Diseases Chlorpyrifos 3.0215991261
MESH:D008113 Liver Neoplasms Fluorouracil 4.3917045692 18383874 15113037 16603448
MESH:D008113 Liver Neoplasms Tamoxifen 4.3916684651
MESH:D055370 Lung Injury Lipopolysaccharides 3.7921114838
MESH:D008175 Lung Neoplasms Fluorouracil 2.4615246190
MESH:D008175 Lung Neoplasms Tamoxifen 2.4618625569
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.5615086387
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.5319428831
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 2.4814580682 16827153 11731420 19196722 19196723
MESH:D020149 Manganese Poisoning Tamoxifen 4.3219453300
MESH:D008545 Melanoma Tamoxifen 1.8519393235 12393984
MESH:D018328 Melanoma, Amelanotic Tamoxifen 3.9515990972
MESH:D001523 Mental Disorders Clozapine 8.2016856516
MESH:D001523 Mental Disorders Mianserin 8.2016856516
MESH:D024821 Metabolic Syndrome X Clozapine 4.2319142101
MESH:D020326 Migraine without Aura Cyclic AMP 4.9411304026
MESH:D009062 Mouth Neoplasms Fluorouracil 3.4616757204 18986760
MESH:D009362 Neoplasm Metastasis Tamoxifen 2.4619393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.4419410462
MESH:D009369 Neoplasms Fluorouracil 2.5118600527 18239605 16928823
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.7719189210 19196722 19200415
MESH:D020258 Neurotoxicity Syndromes Chlorpyrifos 7.8015081274
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 7.8016436463
MESH:D009765 Obesity Clozapine 2.9619142110 18515891
MESH:D010024 Osteoporosis Calcium 3.6417882678
MESH:D010190 Pancreatic Neoplasms Fluorouracil 2.5916929163 15113037 16500647 19003803
MESH:D010554 Personality Disorders 5-Methoxytryptamine 7.2218062943
MESH:D011014 Pneumonia Lipopolysaccharides 4.3312224865 11605937
MESH:D011041 Poisoning Diazinon 4.1417603234
MESH:D011471 Prostatic Neoplasms Fluorouracil 3.3718626508 19082440
MESH:D011471 Prostatic Neoplasms Tamoxifen 3.3715067354
MESH:D011618 Psychotic Disorders Clozapine 4.0215331141
MESH:D012004 Rectal Neoplasms Fluorouracil 3.8218722050 16160472 18286688 15538739
MESH:D012130 Respiratory Hypersensitivity Lipopolysaccharides 3.5810835634
MESH:D012135 Respiratory Sounds Chlorpyrifos 4.4116611668 11874814 17119214
MESH:D012140 Respiratory Tract Diseases Chlorpyrifos 4.6617119214 16611668
MESH:D012559 Schizophrenia marker/mechanism 12165372
MESH:D012559 Schizophrenia Clozapine 2.7120521326 11151749 20452607 18806925 20107430 20168265 20580759 20521320 18855531 17667964 17726453 16141801 11763009 19369910 17123785
MESH:D012640 Seizures 5-Methoxytryptamine 5.1618062943
MESH:D012729 Sex Chromosome Aberrations Chlorpyrifos 5.866418539
MESH:D013088 Spermatocele Tamoxifen 4.0616709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.8119457130
MESH:D013274 Stomach Neoplasms Fluorouracil 1.9917172411 17522103 15786421 16424979 18396642 18567086 16951190 19084572 17498489 19015929
MESH:D013375 Substance Withdrawal Syndrome Mianserin 5.9712749364
MESH:D013921 Thrombocytopenia Lipopolysaccharides 3.9715821434
MESH:D014062 Tongue Neoplasms Fluorouracil 3.7916280240
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 2.2716712894 8653321 17572228
MESH:D014570 Urologic Diseases Diazinon 5.0516487989
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 3.6816803524
MESH:D015430 Weight Gain Clozapine 4.2816402076 20521320 20564506 16141801 20107430 17502770
MESH:D015431 Weight Loss Clozapine 4.8517933447
Pathway ID Pathway Name
KEGG:04020 Calcium signaling pathway
KEGG:04080 Neuroactive ligand-receptor interaction
REACT:14797 Signaling by GPCR
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA29561
    • No data
    Releated disease ID Related disease Name
    PA444516Hypercholesterolemia
    PA444528Hyperlipidemias
    PA444997Muscular Diseases
    PA157379134Myalgia unspecified
    PA445028Myositis
    PA445549Rhabdomyolysis
    PA447198Autistic Disorder
    PA443319Alzheimer Disease
    Releated drug ID Related drug Name
    PA448500atorvastatin
    PA451089pravastatin
    PA451363simvastatin
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB00216 agonist Eletriptan Vasoconstrictor Agents;Anti-inflammatory Agents;Anti-migraine Agents;Selective Serotonin Agonists;Serotonin Agonists
    DB00246 antagonist Ziprasidone Antipsychotics;Dopamine Antagonists;Serotonin Antagonists;Antipsychotic Agents
    DB00247 antagonist Methysergide Vasoconstrictor Agents;Sympatholytics;Serotonin Antagonists
    DB00248 antagonist Cabergoline Antineoplastic Agents;Antiparkinson Agents;Dopamine Agonists
    DB00334 antagonist Olanzapine Antiemetics;Antipsychotics;Antipsychotic Agents;Serotonin Uptake Inhibitors
    DB00363 antagonist Clozapine Antipsychotics;Serotonin Antagonists;Antipsychotic Agents;GABA Antagonists
    DB00751 antagonist Epinastine Histamine H1 Antagonists;Antihistamines;Ophthalmics
    DB01200 antagonist Bromocriptine Antiparkinson Agents;Antidyskinetics;Dopamine Agonists;Hormone Antagonists
    DB01224 antagonist Quetiapine Antipsychotics;Antipsychotic Agents
    DB01238 other/unknown Aripiprazole Antipsychotics;Antipsychotic Agents
    DB06288 antagonist Amisulpride Dopamine Antagonists;Antipsychotic Agents
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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