Annotation Detail for UBAC2
Basic Information
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| Gene Symbol: | UBAC2 ( FLJ26351,FLJ30001,FLJ30548,FLJ42413,MGC90487,PHGDHL1 ) |
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| Gene Full Name: | UBA domain containing 2 |
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| Band: | 13q32.3 |
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| Quick Links | Entrez ID:337867; OMIM: NA; Uniprot ID:UBAC2_HUMAN; ENSEMBL ID: ENSG00000134882; HGNC ID: 20486 |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| C016403 |
2,4-dinitrotoluene |
2,4-dinitrotoluene affects the expression of UBAC2 mRNA | affects expression | 21346803
|
| D015123 |
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of UBAC2 mRNA | decreases expression | 19150397
|
| D006918 |
Hydroxyurea |
Hydroxyurea results in increased mutagenesis of UBAC2 gene | increases mutagenesis | 16868089
|
| D008770 |
Methylnitrosourea |
Methylnitrosourea results in increased mutagenesis of UBAC2 gene | increases mutagenesis | 16868089
|
| D014303 |
Trinitrotoluene |
Trinitrotoluene affects the expression of UBAC2 mRNA | affects expression | 21346803
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000014 |
Abnormalities, Drug-Induced |
|
Trinitrotoluene |
4.72 | 7525203 |
| MESH:D000230 |
Adenocarcinoma |
|
Methylnitrosourea |
3.19 | 15688392 15113128 |
| MESH:D001943 |
Breast Neoplasms |
|
Methylnitrosourea |
3.13 | 14633655 11306469 16253758 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
2,4-dinitrotoluene |
1.78 | 16705839 |
| MESH:D002386 |
Cataract |
|
Methylnitrosourea |
8.65 | 12484553 |
| MESH:D002386 |
Cataract |
|
Trinitrotoluene |
8.65 | 15817613 14694615 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
7.81 | 20889678 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
Methylnitrosourea |
7.81 | 7505956 2727394 |
| MESH:D000013 |
Congenital Abnormalities |
|
Trinitrotoluene |
4.72 | 15095906 |
| MESH:D003490 |
Cyanosis |
|
2,4-dinitrotoluene |
12.89 | 18551238 |
| MESH:D003490 |
Cyanosis |
|
Trinitrotoluene |
12.89 | 18551238 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
2,4-dinitrotoluene |
4.47 | 21346803 18551238 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Trinitrotoluene |
4.47 | 21346803 18551238 |
| MESH:D004938 |
Esophageal Neoplasms |
|
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
2.14 | 20426865 |
| MESH:D005354 |
Fibrosarcoma |
|
Methylnitrosourea |
5.77 | 11555667 |
| MESH:D005910 |
Glioma |
|
Methylnitrosourea |
3.67 | 9825942 |
| MESH:D006529 |
Hepatomegaly |
|
Trinitrotoluene |
4.71 | 15817613 |
| MESH:D007248 |
Infertility, Male |
|
Methylnitrosourea |
8.13 | 7193160 |
| MESH:D007248 |
Infertility, Male |
|
Trinitrotoluene |
8.13 | 12150543 |
| MESH:D007680 |
Kidney Neoplasms |
|
2,4-dinitrotoluene |
3.28 | 16705839 |
| MESH:D007951 |
Leukemia, Myeloid |
|
Hydroxyurea |
5.38 | 16532439 |
| MESH:D017880 |
Limb Deformities, Congenital |
|
Methylnitrosourea |
4.45 | 15526292 |
| MESH:D038061 |
Lower Extremity Deformities, Congenital |
|
Methylnitrosourea |
5.95 | 16080182 |
| MESH:D008175 |
Lung Neoplasms |
|
Methylnitrosourea |
2.70 | 18062963 |
| MESH:D008223 |
Lymphoma |
|
Methylnitrosourea |
4.26 | 16257854 11418001 |
| MESH:D016393 |
Lymphoma, B-Cell |
|
Methylnitrosourea |
5.17 | 14633661 |
| MESH:D008325 |
Mammary Neoplasms, Experimental |
|
Methylnitrosourea |
3.79 | 16619500 14999141 10767621 17131329 15313902 15113128 11807958 19196723 11751437 17020996 16051031 12931682 16944150 15688392 10838139 14633655 16827153 |
| MESH:D009336 |
Necrosis |
|
2,4-dinitrotoluene |
12.54 | 18551238 |
| MESH:D009336 |
Necrosis |
|
Trinitrotoluene |
12.54 | 18551238 |
| MESH:D009369 |
Neoplasms |
|
Methylnitrosourea |
3.45 | 15533788 |
| MESH:D009374 |
Neoplasms, Experimental |
|
Methylnitrosourea |
4.95 | 12696579 |
| MESH:D009442 |
Neurilemmoma |
|
Methylnitrosourea |
6.03 | 11555667 |
| MESH:D009784 |
Occupational Diseases |
|
2,4-dinitrotoluene |
10.40 | 16049721 12819281 |
| MESH:D009784 |
Occupational Diseases |
|
Trinitrotoluene |
10.40 | 12819281 17852074 14694615 |
| MESH:D010190 |
Pancreatic Neoplasms |
|
Methylnitrosourea |
3.46 | 16965848 |
| MESH:D011471 |
Prostatic Neoplasms |
|
Methylnitrosourea |
4.05 | 12376480 15682402 |
| MESH:D012162 |
Retinal Degeneration |
|
Methylnitrosourea |
4.67 | 18155124 18172121 |
| MESH:D012175 |
Retinoblastoma |
|
Methylnitrosourea |
6.03 | 11555667 |
| MESH:D012640 |
Seizures |
|
2,4-dinitrotoluene |
6.98 | 18551238 |
| MESH:D012640 |
Seizures |
|
Trinitrotoluene |
6.98 | 18551238 |
| MESH:D013163 |
Splenomegaly |
|
Trinitrotoluene |
5.69 | 15817613 |
| MESH:D013274 |
Stomach Neoplasms |
|
Methylnitrosourea |
2.70 | 16257854 15930296 18593901 |
| MESH:D013953 |
Thymus Neoplasms |
|
Methylnitrosourea |
5.77 | 11418001 |
| MESH:D013964 |
Thyroid Neoplasms |
|
Methylnitrosourea |
4.19 | 7505956 3078959 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
2,4-dinitrotoluene |
2.39 | 16049721 |
| MESH:D014571 |
Urologic Neoplasms |
|
2,4-dinitrotoluene |
4.86 | 10091137 |
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