Annotation Detail for SPOPL
Basic Information Top
| Gene Symbol: | SPOPL ( FLJ53775 ) |
|---|---|
| Gene Full Name: | speckle-type POZ protein-like |
| Band: | 2q22.1 |
| Quick Links | Entrez ID:339745; OMIM: NA; Uniprot ID:SPOPL_HUMAN; ENSEMBL ID: ENSG00000144228; HGNC ID: 27934 |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Pathway Information| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D000082 | Acetaminophen | Acetaminophen affects the expression of SPOPL mRNA | affects expression | 17562736 |
| D000638 | Amiodarone | Amiodarone results in increased expression of SPOPL mRNA | increases expression | 19774075 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000799 | Angioedema | Acetaminophen | 4.91 | 10982225 | |
| MESH:D001145 | Arrhythmias, Cardiac | Amiodarone | 4.31 | 18218290 20041841 18057881 | |
| MESH:D001281 | Atrial Fibrillation | Amiodarone | 4.27 | 19698954 18651412 | |
| MESH:D001321 | Autistic Disorder | Acetaminophen | 1.39 | 18445737 | |
| MESH:D001778 | Blood Coagulation Disorders | Amiodarone | 4.45 | 19483382 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Acetaminophen | 1.41 | 3084413 | |
| MESH:D002311 | Cardiomyopathy, Dilated | Amiodarone | 3.02 | 15710769 19225199 | |
| MESH:D002341 | Carotid Artery Thrombosis | Amiodarone | 5.97 | 18974383 | |
| MESH:D002386 | Cataract | Acetaminophen | 2.83 | 10977129 | |
| MESH:D056486 | Drug-Induced Liver Injury | Acetaminophen | 4.23 | 15619225 19085960 19923254 18071297 19164858 11461765 17562736 12153990 10774834 14725611 12594235 19739265 11743745 16781746 19370779 16109766 2444490 11529661 11739529 17522070 15968718 10663392 16485898 11421492 19420014 12705907 12392966 14550746 16393943 17906064 16177239 18713872 10915739 12958197 14986274 12540782 11834606 16081117 16227642 11287661 19416960 | |
| MESH:D056486 | Drug-Induced Liver Injury | Amiodarone | 4.23 | 15265979 18218290 | |
| MESH:D056487 | Drug-Induced Liver Injury, Chronic | Acetaminophen | 5.17 | 19426721 | |
| MESH:D005234 | Fatty Liver | Amiodarone | 4.07 | 14986274 | |
| MESH:D005756 | Gastritis | Acetaminophen | 4.74 | 16983495 | |
| MESH:D006529 | Hepatomegaly | Amiodarone | 4.51 | 15265979 | |
| MESH:D006930 | Hyperalgesia | Acetaminophen | 3.11 | 16870215 | |
| MESH:D006937 | Hypercholesterolemia | Amiodarone | 4.42 | 9751232 8137927 | |
| MESH:D007037 | Hypothyroidism | Amiodarone | 5.28 | 17991464 18020914 | |
| MESH:D007674 | Kidney Diseases | Acetaminophen | 2.44 | 12587719 15629191 | |
| MESH:D008064 | Lipidoses | Amiodarone | 3.85 | 17567588 15342952 | |
| MESH:D008107 | Liver Diseases | Acetaminophen | 1.71 | 16611625 12587719 19460945 19784758 19014921 11587558 16610002 12969438 | |
| MESH:D017114 | Liver Failure, Acute | Acetaminophen | 3.74 | 16871587 17185352 | |
| MESH:D008133 | Long QT Syndrome | Amiodarone | 3.96 | 17391786 11989578 15350150 | |
| MESH:D008171 | Lung Diseases | Amiodarone | 3.68 | 12587719 | |
| MESH:D017563 | Lung Diseases, Interstitial | Amiodarone | 5.55 | 18516814 | |
| MESH:D008546 | Melanoma, Experimental | Acetaminophen | 4.33 | 19513568 | |
| MESH:D009181 | Mycoses | Amiodarone | 5.97 | 17974566 12754197 | |
| MESH:D019636 | Neurodegenerative Diseases | Acetaminophen | 3.31 | 18514411 | |
| MESH:D010146 | Pain | Acetaminophen | 2.82 | 16870215 | |
| MESH:D011658 | Pulmonary Fibrosis | Amiodarone | 2.99 | 12832656 12490602 11597910 | |
| OMIM:609620 | SHORT QT SYNDROME 1 | Amiodarone | 5.97 | 18724381 | |
| MESH:D013276 | Stomach Ulcer | Amiodarone | 3.86 | 18087811 | |
| MESH:D013610 | Tachycardia | Amiodarone | 4.96 | 11238279 | |
| MESH:D017180 | Tachycardia, Ventricular | Amiodarone | 4.86 | 19225199 | |
| MESH:D013959 | Thyroid Diseases | Amiodarone | 5.83 | 19731979 | |
| MESH:D013971 | Thyrotoxicosis | Amiodarone | 5.62 | 18020914 19584973 | |
| MESH:D016171 | Torsades de Pointes | Amiodarone | 5.08 | 11989578 17467628 | |
| MESH:D014581 | Urticaria | Acetaminophen | 3.58 | 10982225 |
| No data |