AutismKB 2.0

Annotation Detail for ID2


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Basic Information Top
Gene Symbol:ID2 ( GIG8,ID2A,ID2H,MGC26389,bHLHb26 )
Gene Full Name: inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
Band: 2p25.1
Quick LinksEntrez ID:3398; OMIM: 600386; Uniprot ID:ID2_HUMAN; ENSEMBL ID: ENSG00000115738; HGNC ID: 5361
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04350TGF-beta signaling pathway
No data
Pathway IDPathway Name
200171Validated targets of C-MYC transcriptional repression
200106Regulation of Wnt-mediated beta catenin signaling and target gene transcription
200172HIF-1-alpha transcription factor network
200045Validated targets of C-MYC transcriptional activation
No data
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1934Cancer
2047Rett syndrome
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of ID2 mRNAaffects expression 21346803
C025160 3-aminobenzamide 3-aminobenzamide results in decreased expression of ID2 mRNAdecreases expression 15670817
D000082 Acetaminophen Acetaminophen affects the expression of ID2 mRNAaffects expression 17562736
D000111 Acetylcysteine Acetylcysteine results in decreased expression of ID2 mRNAdecreases expression 16084531
D013196 Dihydrotestosterone Dihydrotestosterone results in increased expression of ID2 mRNAincreases expression 16541417
D000643 Ammonium Chloride Ammonium Chloride affects the expression of ID2 mRNAaffects expression 16483693
D001151 Arsenic Arsenic results in decreased expression of ID2 mRNAdecreases expression 16835338
C006632 arsenic trioxide arsenic trioxide results in decreased expression of ID2 mRNAdecreases expression 15761015
D001554 Benzene [Benzene co-treated with methylmercury II co-treated with Trichloroethylene] results in increased expression of ID2 mRNAaffects cotreatment|increases expression 17905399
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of ID2 mRNAincreases expression 19150397
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in increased expression of ID2 mRNAincreases expression 14729362
15003993
D002087 Butyrates Butyrates results in increased expression of ID2 mRNAincreases expression 14674679
D019256 Cadmium Chloride [sodium arsenite co-treated with Cadmium Chloride co-treated with chromium oxide co-treated with chromous chloride co-treated with lead acetate] results in decreased expression of ID2 mRNAaffects cotreatment|decreases expression 12634122
D002713 Chlorine Chlorine results in decreased expression of ID2 mRNAdecreases expression 18636392
D002713 Chlorine [Ozone co-treated with Chlorine] affects the expression of ID2 mRNAaffects cotreatment|affects expression 18636392
D020111 Chlorodiphenyl (54% Chlorine) Chlorodiphenyl (54% Chlorine) results in decreased expression of ID2 mRNAdecreases expression 16934159
C023600 chromium oxide [sodium arsenite co-treated with Cadmium Chloride co-treated with chromium oxide co-treated with chromous chloride co-treated with lead acetate] results in decreased expression of ID2 mRNAaffects cotreatment|decreases expression 12634122
C017133 chromous chloride [sodium arsenite co-treated with Cadmium Chloride co-treated with chromium oxide co-treated with chromous chloride co-treated with lead acetate] results in decreased expression of ID2 mRNAaffects cotreatment|decreases expression 12634122
D003024 Clozapine Clozapine results in increased expression of ID2 mRNAincreases expression 12437575
D016572 Cyclosporine Cyclosporine results in decreased expression of ID2 mRNAdecreases expression 20106945
C014347 decitabine [decitabine co-treated with vorinostat] affects the expression of ID2 mRNAaffects cotreatment|affects expression 17330099
C014347 decitabine decitabine results in increased expression of ID2 mRNAincreases expression 19194470
D004041 Dietary Fats Dietary Fats results in decreased expression of ID2 mRNAdecreases expression 18042831
D004041 Dietary Fats Dietary Fats results in increased expression of ID2 mRNAincreases expression 18042831
D002117 Calcitriol Calcitriol results in decreased expression of ID2 mRNAdecreases expression 16002434
D004317 Doxorubicin ID2 protein affects the susceptibility to Doxorubicinaffects response to substance 16217747
C045651 epigallocatechin gallate epigallocatechin gallate results in decreased expression of ID2 mRNAdecreases expression 16084531
D004958 Estradiol Estradiol results in decreased expression of ID2 mRNAdecreases expression 20106945
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of ID2 mRNAdecreases expression 17475347
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of ID2 mRNAdecreases expression 17942748
17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of ID2 mRNAdecreases expression 15834898
12655037
17557909
D011345 Fenofibrate Fenofibrate results in decreased expression of ID2 mRNAdecreases expression 11798191
D005472 Fluorouracil Fluorouracil results in decreased expression of ID2 proteindecreases expression 15352031
D005472 Fluorouracil Fluorouracil results in increased expression of ID2 mRNAincreases expression 16557594
D005472 Fluorouracil ID2 protein affects the susceptibility to Fluorouracilaffects response to substance 15352031
D005472 Fluorouracil TP53 protein promotes the reaction [Fluorouracil results in increased expression of ID2 mRNA]increases expression|increases reaction 16557594
D005472 Fluorouracil ID2 protein affects the susceptibility to Fluorouracilaffects response to substance 15016739
D006220 Haloperidol Haloperidol results in decreased expression of ID2 mRNAdecreases expression 12437575
D006220 Haloperidol Haloperidol results in increased expression of ID2 mRNAincreases expression 12437575
D006247 Harmine Harmine inhibits the reaction [WNT3A protein results in decreased expression of ID2 mRNA]decreases expression|decreases reaction 20519739
D006851 Hydrochloric Acid Hydrochloric Acid results in increased expression of ID2 mRNAincreases expression 15046208
C051890 irinotecan irinotecan metabolite results in decreased expression of ID2 mRNAdecreases expression 15956246
C051890 irinotecan irinotecan results in decreased expression of ID2 mRNAdecreases expression 15956246
C008261 lead acetate [sodium arsenite co-treated with Cadmium Chloride co-treated with chromium oxide co-treated with chromous chloride co-treated with lead acetate] results in decreased expression of ID2 mRNAaffects cotreatment|decreases expression 12634122
D008345 Manganese Manganese results in increased expression of ID2 mRNAincreases expression 17175027
C025340 manganese chloride manganese chloride results in increased expression of ID2 mRNAincreases expression 17175027
D008713 Methimazole Methimazole results in decreased expression of ID2 mRNAdecreases expression 17403546
C005219 methyl cellosolve methyl cellosolve results in decreased expression of ID2 mRNAdecreases expression 19643169
D008748 Methylcholanthrene Methylcholanthrene results in increased expression of ID2 mRNAincreases expression 20713471
C030957 methylmercury II [Benzene co-treated with methylmercury II co-treated with Trichloroethylene] results in increased expression of ID2 mRNAaffects cotreatment|increases expression 17905399
C008493 methylselenic acid methylselenic acid affects the expression of ID2 mRNAaffects expression 14617803
C029938 nickel sulfate nickel sulfate results in increased expression of ID2 mRNAincreases expression 16780908
D005996 Nitroglycerin Nitroglycerin results in increased expression of ID2 mRNAincreases expression 12102619
D010100 Oxygen Oxygen deficiency results in increased expression of ID2 mRNAincreases expression 17175027
D010126 Ozone [Ozone co-treated with Chlorine] affects the expression of ID2 mRNAaffects cotreatment|affects expression 18636392
C041786 palm oil palm oil results in decreased expression of ID2 mRNAdecreases expression 18042831
C041786 palm oil palm oil results in increased expression of ID2 mRNAincreases expression 18042831
C055778 panaxydol panaxydol results in decreased expression of ID2 mRNAdecreases expression 19450571
C494474 perchlorate perchlorate results in decreased expression of ID2 mRNAdecreases expression 17403546
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in decreased expression of ID2 mRNA]affects reaction|decreases expression 19482888
D010634 Phenobarbital Phenobarbital results in decreased expression of ID2 mRNAdecreases expression 19482888
C006253 pirinixic acid pirinixic acid results in decreased expression of ID2 mRNAdecreases expression 11798191
18445702
20059764
C006253 pirinixic acid PPARA protein promotes the reaction [pirinixic acid results in decreased expression of ID2 mRNA]decreases expression|increases reaction 20059764
C467566 pomalidomide pomalidomide results in increased expression of ID2 mRNAincreases expression 15292067
D011374 Progesterone Progesterone results in increased expression of ID2 mRNAincreases expression 18037150
D011435 Propyl Gallate Propyl Gallate affects the expression of ID2 mRNAaffects expression 18539377
D011441 Propylthiouracil Propylthiouracil results in decreased expression of ID2 mRNAdecreases expression 17403546
C488333 Ro 65-7199 Ro 65-7199 affects the expression of ID2 mRNAaffects expression 14610520
C488334 Ro 66-0074 Ro 66-0074 results in increased expression of ID2 mRNAincreases expression 14610520
D012643 Selenium Selenium results in decreased expression of ID2 mRNAdecreases expression 19244175
C009250 sevoflurane sevoflurane affects the expression of ID2 mRNAaffects expression 15967596
C009277 sodium arsenate sodium arsenate results in decreased expression of ID2 mRNAdecreases expression 12727804
C017947 sodium arsenite [sodium arsenite co-treated with Cadmium Chloride co-treated with chromium oxide co-treated with chromous chloride co-treated with lead acetate] results in decreased expression of ID2 mRNAaffects cotreatment|decreases expression 12634122
C017947 sodium arsenite sodium arsenite results in decreased expression of ID2 mRNAdecreases expression 12727804
C017947 sodium arsenite sodium arsenite results in increased expression of ID2 mRNAincreases expression 16966095
D014284 Triiodothyronine Triiodothyronine results in increased expression of ID2 mRNAincreases expression 17403546
D013974 Thyroxine Thyroxine results in decreased expression of ID2 mRNAdecreases expression 17403546
D013974 Thyroxine Thyroxine results in increased expression of ID2 mRNAincreases expression 17403546
D013629 Tamoxifen Tamoxifen affects the expression of ID2 mRNAaffects expression 17555576
C021751 tanshinone tanshinone results in increased expression of ID2 mRNAincreases expression 15849732
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of ID2 mRNAincreases expression 20106945
11489354
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of ID2 mRNAdecreases expression 19933214
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of ID2 mRNAincreases expression 17949056
D013853 Thioacetamide Thioacetamide results in decreased expression of ID2 mRNAdecreases expression 16297948
D014212 Tretinoin Tretinoin affects the expression of ID2 mRNAaffects expression 16054129
D014212 Tretinoin Tretinoin results in decreased expression of ID2 mRNAdecreases expression 17310985
D014212 Tretinoin Tretinoin results in increased expression of ID2 mRNAincreases expression 16494909
16129123
17218384
17138961
D014241 Trichloroethylene [Benzene co-treated with methylmercury II co-treated with Trichloroethylene] results in increased expression of ID2 mRNAaffects cotreatment|increases expression 17905399
D014501 Uranium Uranium affects the expression of ID2 mRNAaffects expression 15672453
C005460 uranyl acetate uranyl acetate affects the expression of ID2 mRNAaffects expression 15672453
C081489 valsartan valsartan inhibits the reaction [AGT protein results in decreased expression of ID2 mRNA]decreases expression|decreases reaction 19225232
D014747 Vinblastine ID2 protein affects the susceptibility to Vinblastineaffects response to substance 16217747
D014810 Vitamin E Vitamin E results in decreased expression of ID2 mRNAdecreases expression 19244175
C111237 vorinostat [decitabine co-treated with vorinostat] affects the expression of ID2 mRNAaffects cotreatment|affects expression 17330099
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 3.8214745880
MESH:D000014 Abnormalities, Drug-Induced methyl cellosolve 10.276499812 3652986 6474471
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 10.276195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 10.2715322242 14514962 11752688
MESH:D000138 Acidosis Ammonium Chloride 8.3718287403
MESH:D000138 Acidosis Hydrochloric Acid 8.3720872349 19262391 15920416 16144966 11574821 12771618
MESH:D000141 Acidosis, Renal Tubular Hydrochloric Acid 5.0717183249
MESH:D000142 Acidosis, Respiratory Hydrochloric Acid 5.0920597076
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.2217505938
MESH:D055371 Acute Lung Injury Chlorine 21.5720601635
MESH:D055371 Acute Lung Injury Hydrochloric Acid 21.5716759491 11850527 19060228 19760209 15970105 11953099 19094174
MESH:D055371 Acute Lung Injury nickel sulfate 21.5716100012 11954676 12718980 19131640
MESH:D055371 Acute Lung Injury Oxygen 21.5716759491
MESH:D055371 Acute Lung Injury pirinixic acid 21.5718653653
MESH:D000230 Adenocarcinoma arsenic trioxide 10.8711798837 19825857
MESH:D000230 Adenocarcinoma Doxorubicin 10.8717418594
MESH:D000230 Adenocarcinoma Estradiol 10.8711473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 10.8714692618
MESH:D000230 Adenocarcinoma Fluorouracil 10.8717638652
MESH:D000236 Adenoma Methylcholanthrene 3.056695378 10545420
MESH:D018248 Adenoma, Liver Cell Phenobarbital 13.1817620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 13.1816434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 13.1816835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 3.9715276417
MESH:D018246 Adrenocortical Adenoma Arsenic 11.3817306315
MESH:D018246 Adrenocortical Adenoma sodium arsenite 11.3817306315 16712894
MESH:D000380 Agranulocytosis Clozapine 4.3616160616 12649775 14617031
MESH:D000419 Albuminuria Doxorubicin 3.8621441931
MESH:D000505 Alopecia Tretinoin 3.0315955085
MESH:D000544 Alzheimer Disease Ozone 2.2515513908
MESH:D000740 Anemia Fluorouracil 6.6017963324 16511603 15504547
MESH:D000740 Anemia Tetrachlorodibenzodioxin 6.6011748828
MESH:D000741 Anemia, Aplastic Benzene 3.8017661222 11369114 14761424
MESH:D000748 Anemia, Macrocytic methyl cellosolve 5.623699323
MESH:D000756 Anemia, Sideroblastic Manganese 8.8816910769
MESH:D000756 Anemia, Sideroblastic manganese chloride 8.8816910769
MESH:D000799 Angioedema Acetaminophen 3.1210982225
MESH:D000860 Anoxia Hydrochloric Acid 9.2615090967
MESH:D000860 Anoxia Oxygen 9.2620872349
MESH:D020261 Arsenic Poisoning marker/mechanism 16835338
MESH:D020261 Arsenic Poisoning Arsenic 2.6212569548 16251483 16835338 18414634
MESH:D001161 Arteriosclerosis Dietary Fats 7.6015238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 7.6011256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 5.6015885639
MESH:D001169 Arthritis, Experimental Tretinoin 5.6016412693
MESH:D001172 Arthritis, Rheumatoid Ozone 3.8915570426
MESH:D001172 Arthritis, Rheumatoid Tretinoin 3.8916292516
MESH:D053627 Asthenozoospermia methyl cellosolve 4.813987992
MESH:D001249 Asthma epigallocatechin gallate 6.3716516891
MESH:D001249 Asthma Ozone 6.3716373670 17854713
MESH:D001249 Asthma Tretinoin 6.3716456186
MESH:D050197 Atherosclerosis Arsenic 8.4712928151 19371607
MESH:D050197 Atherosclerosis Methylcholanthrene 8.4711922910
MESH:D050197 Atherosclerosis Oxygen 8.4716391483
MESH:D001284 Atrophy methyl cellosolve 4.516705890 2626667 3699323
MESH:D001321 Autistic Disorder Acetaminophen 2.1518445737
MESH:D001321 Autistic Disorder Haloperidol 2.1518080171 19368416
MESH:D001327 Autoimmune Diseases epigallocatechin gallate 4.3719761891
MESH:D001471 Barrett Esophagus Tretinoin 3.7216935849
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 33.3416206674
MESH:D001778 Blood Coagulation Disorders Hydrochloric Acid 33.3415920416
MESH:D001778 Blood Coagulation Disorders pirinixic acid 33.3419483382
MESH:D001778 Blood Coagulation Disorders Propylthiouracil 33.3419483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 33.3412125929
MESH:D001778 Blood Coagulation Disorders Thioacetamide 33.3419483382
MESH:D001778 Blood Coagulation Disorders Tretinoin 33.3416206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.0615340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.2715746008
MESH:D001855 Bone Marrow Diseases Benzene 4.5016183116
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 3.9714601052
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 4.6117868700
MESH:D001930 Brain Injuries Progesterone 3.5615665606 15380490 15845082
MESH:D001932 Brain Neoplasms Doxorubicin 3.1917150277
MESH:D001943 Breast Neoplasms Benzene 13.7111921183 17162533
MESH:D001943 Breast Neoplasms Calcitriol 13.7111237771
MESH:D001943 Breast Neoplasms decitabine 13.7119208741 18320071
MESH:D001943 Breast Neoplasms Dietary Fats 13.7120435547
MESH:D001943 Breast Neoplasms Doxorubicin 13.7118382427 18628466 17369602 19526202 11325840 15939500 15993339 15136595 16826403 16096432 15692762 16264153 16322301 18695136 16115903 16595493 15567936 15634643 17983394 15994142 18234424 15668708 16935488 17426702
MESH:D001943 Breast Neoplasms Estradiol 13.7117289903 18497071 12948864 16675129 19861407 17261762 14630087 17018787
MESH:D001943 Breast Neoplasms Fluorouracil 13.7115136595 16110121 19217205 18357371 16595493 16557594 18608205
MESH:D001943 Breast Neoplasms Methylcholanthrene 13.7117474063
MESH:D001943 Breast Neoplasms Oxygen 13.7117263869
MESH:D001943 Breast Neoplasms Progesterone 13.7116175315 15562024 17614352
MESH:D001943 Breast Neoplasms Tamoxifen 13.7118351453 19410462 16202921 18997820 15565566 18821012 20544844 17261762 19142967 19200415 18629630 19289846 18815881 17440819 19189212 16818667 19084267 19244106 20135344 17049068 19011961 19487384 19221464 21152245 11161223 19066611 19115204 17242785 17893378 18425577 19155303 16873071 19189210 20859285 19288272 18984771 15668708 20065188 18855134 21138602 19103187 20390343 19059307 20005174 16273361
MESH:D001943 Breast Neoplasms tanshinone 13.7115849732 19885617
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 13.7120435547
MESH:D001943 Breast Neoplasms Tretinoin 13.7116873071 16443354 16166294
MESH:D001943 Breast Neoplasms Trichloroethylene 13.7115986119
MESH:D001943 Breast Neoplasms vorinostat 13.7116144943
MESH:D016535 Bronchial Hyperreactivity Hydrochloric Acid 7.0112378975
MESH:D016535 Bronchial Hyperreactivity Ozone 7.0115516495 16777450 18417511 17626835 18315731 19059883 14754758
MESH:D001986 Bronchial Spasm Hydrochloric Acid 4.7415578804
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 3.8816813970
MESH:D002051 Burkitt Lymphoma arsenic trioxide 3.6611589617
MESH:D002100 Cachexia Ozone 4.0316183385
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 3.7516111702
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 3.2416050911
MESH:D002276 Carcinoid Tumor Doxorubicin 9.9416051944
MESH:D002276 Carcinoid Tumor Fluorouracil 9.9416051944
MESH:D002277 Carcinoma Fluorouracil 10.6317121937
MESH:D002277 Carcinoma Methylcholanthrene 10.6310545420
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 10.6316835633
MESH:D002280 Carcinoma, Basal Cell Arsenic 3.1415504454 17687452
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 3.8119066611
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.4316168501
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 27.7416705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 27.743084413
MESH:D006528 Carcinoma, Hepatocellular Arsenic 27.7417306315 16507464
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 27.7411135700 14691202 15553829 16217749 15073043
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 27.7418059187 16023760 17876044 16234567
MESH:D006528 Carcinoma, Hepatocellular Estradiol 27.7416924424
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 27.7417088986 16332177 18930000 17045692 16799960 17971768
MESH:D006528 Carcinoma, Hepatocellular panaxydol 27.7419450571
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 27.741701930 17173139 6705139 20935162 20007298
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 27.7416507464 17306315 15276417
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 27.7416924424
MESH:D006528 Carcinoma, Hepatocellular Thioacetamide 27.7417997003
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 27.741917145
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.1519014326
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 8.6416201981 1485588
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 8.6418695887
MESH:D002292 Carcinoma, Renal Cell Vinblastine 8.641485588
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.4912490120
MESH:D002294 Carcinoma, Squamous Cell Acetylcysteine 21.1517015178
MESH:D002294 Carcinoma, Squamous Cell Arsenic 21.1517687452 15504454 18922899
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 21.1511237771
MESH:D002294 Carcinoma, Squamous Cell decitabine 21.1519215824
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 21.156189445
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 21.1516757204 16280240 17066447 18986760
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 21.1518572023
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 21.1516096774 16051514
MESH:D002295 Carcinoma, Transitional Cell Arsenic 7.4218640142
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 7.4217572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 9.0716120746 18670907 18850075
MESH:D006332 Cardiomegaly Thyroxine 9.0718093424
MESH:D006332 Cardiomegaly valsartan 9.0719597038
MESH:D009202 Cardiomyopathies Doxorubicin 6.6316612575 17308081 17007740 15476868 15811867 18627295 17928571 17131338 17924179 16731534 15792986 16364871 16952015 16109756 16455267 17519947 17382496 17329180 16242529 17351982 16278810 16651473 17974986 15505089 16269455
MESH:D009202 Cardiomyopathies valsartan 6.6316247790
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.6516243910 17334414
MESH:D002318 Cardiovascular Diseases Arsenic 6.1315738583 19152805 17938729
MESH:D002318 Cardiovascular Diseases valsartan 6.1311230374
MESH:D002340 Carotid Artery Diseases Arsenic 3.6918022660 16973168
MESH:D002375 Catalepsy Haloperidol 4.201977408 15215559
MESH:D002386 Cataract Acetaminophen 5.6710977129
MESH:D002386 Cataract Tretinoin 5.6717460283
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 19.6220889678
MESH:D002471 Cell Transformation, Neoplastic Acetylcysteine 19.6218226522
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 19.6212371664
MESH:D002471 Cell Transformation, Neoplastic Estradiol 19.6218566989
MESH:D002471 Cell Transformation, Neoplastic Methylcholanthrene 19.6216192471
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 19.6219524636 20056578
MESH:D002493 Central Nervous System Diseases Phenobarbital 3.554080065
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 3.8816129372
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 7.5116835633
MESH:D018281 Cholangiocarcinoma Thioacetamide 7.5118291259
MESH:D002764 Cholecystitis methyl cellosolve 5.076499794
MESH:D002779 Cholestasis Cyclosporine 10.1419486331
MESH:D002779 Cholestasis Ethinyl Estradiol 10.1417681005 17110522 16105132 15861022 16919318 11677210 17333356
MESH:D002779 Cholestasis pirinixic acid 10.1419176532
MESH:D002822 Choriocarcinoma Tretinoin 4.4316461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 4.5615668235 8697196 16354765 15340226 12621046
MESH:D002972 Cleft Palate Tretinoin 4.569407595
MESH:D003072 Cognition Disorders Clozapine 4.2717123785
MESH:D003092 Colitis Selenium 7.2017936198
MESH:D003092 Colitis Tretinoin 7.2017035595
MESH:D003110 Colonic Neoplasms Butyrates 6.7415936596
MESH:D003110 Colonic Neoplasms decitabine 6.7417616700
MESH:D003110 Colonic Neoplasms Fluorouracil 6.7418772588 15001691 17018589 16510598 16340194 17169374 17172411 17725105 17287894 17016597
MESH:D003110 Colonic Neoplasms irinotecan 6.7417725105 17287894
MESH:D015179 Colorectal Neoplasms arsenic trioxide 6.9620501625
MESH:D015179 Colorectal Neoplasms decitabine 6.9618981723
MESH:D015179 Colorectal Neoplasms Doxorubicin 6.9618802399 18259882
MESH:D015179 Colorectal Neoplasms Fluorouracil 6.9616331619 18288408 18383874 18448328 20501625 17594712 17695437 18949393 16303861 17094418 17454858 17016601 18802399 16391804 17401013 15289873 16524972 17255274 18509181 14970324 16282729 15148649
MESH:D015179 Colorectal Neoplasms irinotecan 6.9617454858 18259882 15273666 16391804 16303861 17159606 18509181
MESH:D015179 Colorectal Neoplasms Vinblastine 6.9618802399
MESH:D000013 Congenital Abnormalities methyl cellosolve 7.396499821 12530607
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 7.3914669216 17141729
MESH:D003324 Coronary Artery Disease valsartan 3.5917719468
MESH:D023903 Coronary Restenosis arsenic trioxide 3.5012609071
MESH:D003384 Coxsackievirus Infections valsartan 5.1320392896
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 9.8610525206
MESH:D019465 Craniofacial Abnormalities Benzene 9.8615643154
MESH:D019465 Craniofacial Abnormalities lead acetate 9.8619769572
MESH:D019465 Craniofacial Abnormalities sodium arsenate 9.8610525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 9.8610048152 15322242 20055451
MESH:D019465 Craniofacial Abnormalities Tretinoin 9.869142499 10589399 9664655 16925845 9211117 17551590 14991402 8800419 9224671 9125849
MESH:D019465 Craniofacial Abnormalities Vitamin E 9.8619769572
MESH:D003490 Cyanosis 2,4-dinitrotoluene 3.3218551238
MESH:D003550 Cystic Fibrosis Acetylcysteine 3.7619747007
MESH:D003556 Cystitis Hydrochloric Acid 4.7419279288 12599022 20719367 12853844
MESH:D018856 Cystitis, Interstitial Hydrochloric Acid 5.0917714534
MESH:D007644 Darier Disease Fluorouracil 4.0816733453
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 8.7215213294
MESH:D016757 Death, Sudden, Cardiac Haloperidol 8.7220210726
MESH:D003704 Dementia Haloperidol 3.9411575062
MESH:D003711 Demyelinating Diseases Tamoxifen 3.6619031437
MESH:D003872 Dermatitis Benzene 4.0715902427
MESH:D017449 Dermatitis, Allergic Contact nickel sulfate 3.0316823706 16780908 11298694
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.0418249437
MESH:D003921 Diabetes Mellitus, Experimental valsartan 4.0111508273
MESH:D003924 Diabetes Mellitus, Type 2 Clozapine 5.9016402076
MESH:D003924 Diabetes Mellitus, Type 2 epigallocatechin gallate 5.9016988119
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 5.9017107852
MESH:D003928 Diabetic Nephropathies Estradiol 11.6119279558
MESH:D003928 Diabetic Nephropathies Tamoxifen 11.6119279558
MESH:D003928 Diabetic Nephropathies valsartan 11.6111427623 18630688
MESH:D003929 Diabetic Neuropathies Progesterone 3.7917187935
MESH:D003967 Diarrhea vorinostat 3.8420479100
MESH:D006970 Disorders of Excessive Somnolence Clozapine 4.8315331141
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 23.4121346803 18551238
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 23.4111529661 15968718 12594235 14725611 10774834 12958197 10663392 10915739 11743745 16781746 11739529 19085960 12153990 11287661 19420014 16177239 15619225 11421492 18713872 18071297 14550746 19739265 12392966 19370779 12540782 17522070 19164858 16227642 16485898 11834606 16393943 19416960 17562736 16081117 19923254 17906064 2444490 12705907 11461765 14986274 16109766
MESH:D056486 Drug-Induced Liver Injury Acetylcysteine 23.4111287661
MESH:D056486 Drug-Induced Liver Injury Chlorodiphenyl (54% Chlorine) 23.4117851650
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 23.4117416283
MESH:D056486 Drug-Induced Liver Injury Selenium 23.4115131321
MESH:D056486 Drug-Induced Liver Injury sodium arsenate 23.4118186108
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 23.4120420201
MESH:D056486 Drug-Induced Liver Injury Thioacetamide 23.4112963478
MESH:D056486 Drug-Induced Liver Injury Trichloroethylene 23.417120509
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.3719426721
MESH:D004362 Drug Toxicity Doxorubicin 6.2718602426
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 6.2711462148
MESH:D050171 Dyslipidemias Clozapine 11.5316402076
MESH:D050171 Dyslipidemias Dietary Fats 11.5318367378
MESH:D050171 Dyslipidemias Fenofibrate 11.5316707586
MESH:D004417 Dyspnea Chlorine 8.2820016425
MESH:D004417 Dyspnea Oxygen 8.2820016425
MESH:D004421 Dystonia Phenobarbital 3.341851702
MESH:C538011 Eales disease Vitamin E 3.989068938
MESH:D004487 Edema pirinixic acid 4.4612083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 4.4611000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 9.5318230668 15322242 16714409
MESH:D004489 Edema, Cardiac Tretinoin 9.5318230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 16.3915138306
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 16.3912538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 16.3917692515
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 16.3919031437
MESH:D004701 Endocrine Gland Neoplasms decitabine 4.3919294695
MESH:D016889 Endometrial Neoplasms Doxorubicin 18.0317359293
MESH:D016889 Endometrial Neoplasms Estradiol 18.0318566989 11473722 19148513
MESH:D016889 Endometrial Neoplasms Fenofibrate 18.0316569247
MESH:D016889 Endometrial Neoplasms Tamoxifen 18.0317893378 16202921 20544844 19155303
MESH:D016889 Endometrial Neoplasms Tretinoin 18.0316569247
MESH:D004715 Endometriosis Progesterone 6.8516134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 6.859294722 10568697
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 4.4318037988
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 3.413659116
MESH:D004828 Epilepsies, Partial Phenobarbital 3.153922381 11558140
MESH:D004827 Epilepsy Phenobarbital 2.4820417680
MESH:D004832 Epilepsy, Absence Phenobarbital 2.936401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 3.557750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 3.313659116
MESH:D004935 Esophageal Diseases Hydrochloric Acid 5.0819566590
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 5.8020426865
MESH:D004938 Esophageal Neoplasms arsenic trioxide 5.8012903497
MESH:D004938 Esophageal Neoplasms Fluorouracil 5.8017638652 15173087 16785472 16337965 16481741
MESH:D004941 Esophagitis Hydrochloric Acid 5.2812928072
MESH:D004942 Esophagitis, Peptic Hydrochloric Acid 5.2920516732 14621274 11346197
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 6.9811564622
MESH:D005124 Eye Abnormalities Tretinoin 6.9816938888 9664655
MESH:D005221 Fatigue vorinostat 4.8820479100
MESH:D005218 Fat Necrosis Thioacetamide 4.9916456712
MESH:D005234 Fatty Liver arsenic trioxide 22.4515073043
MESH:D005234 Fatty Liver Cyclosporine 22.4519224547
MESH:D005234 Fatty Liver Dietary Fats 22.4517967931 19004024 19551842 18296743
MESH:D005234 Fatty Liver Ethinyl Estradiol 22.4515345470
MESH:D005234 Fatty Liver pirinixic acid 22.4520131406 19236843
MESH:D005234 Fatty Liver Tamoxifen 22.4514986274 19224547
MESH:D052776 Female Urogenital Diseases Tamoxifen 2.7616709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 2.7611858732
MESH:D005317 Fetal Growth Retardation lead acetate 4.7019769572
MESH:D005327 Fetal Resorption methyl cellosolve 4.826499812 3987992 6474471 6499821
MESH:D020567 Fetal Weight methyl cellosolve 5.076499812 6474471 6499821
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 3.8114745880
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 9.0819069698
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 9.0819069698
MESH:D005354 Fibrosarcoma Methylcholanthrene 4.2314633661 10962813
MESH:D005355 Fibrosis Cyclosporine 25.5912639820 12168785
MESH:D005355 Fibrosis Dietary Fats 25.5918296743
MESH:D005355 Fibrosis Hydrochloric Acid 25.5918497604
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 25.5920067830
MESH:D005355 Fibrosis Tretinoin 25.5917994277
MESH:D005355 Fibrosis valsartan 25.5916893502
MESH:D005532 Foot Deformities, Congenital methyl cellosolve 4.803652986
MESH:D005534 Foot Diseases Arsenic 4.836392382
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.5816904648
MESH:D005739 Gas Poisoning Chlorine 15.7120016425
MESH:D005739 Gas Poisoning Hydrochloric Acid 15.7112378975
MESH:D005739 Gas Poisoning Oxygen 15.7120016425
MESH:D005756 Gastritis Acetaminophen 2.9516983495
MESH:D005764 Gastroesophageal Reflux Hydrochloric Acid 4.6512212954 19957777 20545468 19951613 20616304 20516732
MESH:D005833 Genital Neoplasms, Female sodium arsenite 3.9716452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.508708960
MESH:D005909 Glioblastoma Doxorubicin 9.1117150277
MESH:D005909 Glioblastoma Manganese 9.1117043766
MESH:D005909 Glioblastoma Tretinoin 9.1117312396
MESH:D005910 Glioma Fluorouracil 5.3916145905
MESH:D005910 Glioma tanshinone 5.3916955220
MESH:D015432 Glomerulonephritis, Membranoproliferative valsartan 4.8616928621
MESH:D018149 Glucose Intolerance sodium arsenate 4.4219446573
MESH:D006042 Goiter perchlorate 4.6418801409
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 3.8710696789
MESH:D006261 Headache Nitroglycerin 4.4711554966 11284996
MESH:D006258 Head and Neck Neoplasms decitabine 14.2319215824
MESH:D006258 Head and Neck Neoplasms Doxorubicin 14.2315692506
MESH:D006258 Head and Neck Neoplasms Fluorouracil 14.2318337622 15162350 15102660
MESH:D006258 Head and Neck Neoplasms Tretinoin 14.2316096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.4316084493
MESH:D006356 Heartburn Hydrochloric Acid 5.0819566590
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 8.6311294989 10048152
MESH:D006330 Heart Defects, Congenital Tretinoin 8.639664655 14991402
MESH:D006330 Heart Defects, Congenital Vitamin E 8.6316080930
MESH:D006331 Heart Diseases Doxorubicin 2.9716144979 16707910 16330681 12587719 18674790 17888722 16244371 16879835 17875725 16495754 18006777 16244372 14766674
MESH:D006333 Heart Failure Doxorubicin 12.9617481944
MESH:D006333 Heart Failure pirinixic acid 12.9620558911
MESH:D006333 Heart Failure Selenium 12.9617162251
MESH:D006333 Heart Failure valsartan 12.9619027736
MESH:D006345 Heart Septal Defects, Ventricular methyl cellosolve 5.076499821
MESH:D006394 Hemangiosarcoma Doxorubicin 3.2615692506
MESH:D006402 Hematologic Diseases Benzene 3.9916183116
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 3.7115720958
MESH:D006461 Hemolysis methyl cellosolve 4.7317874071
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.6911000095
MESH:D006501 Hepatic Encephalopathy Thioacetamide 3.9318665440 15929193 17276928
MESH:D006505 Hepatitis Thioacetamide 3.5416456712
MESH:D006529 Hepatomegaly Phenobarbital 10.3916109766
MESH:D006529 Hepatomegaly pirinixic acid 10.3918467677 16221962 19176532 19772884
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 10.3915340226 16120746 12621046
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.4016490937 16863852
MESH:D006558 Herpes Genitalis Estradiol 4.3015709030
MESH:D006689 Hodgkin Disease Doxorubicin 8.9118501091 17606976 15147373
MESH:D006689 Hodgkin Disease sodium arsenite 8.9112676792
MESH:D006689 Hodgkin Disease Vinblastine 8.9118501091 18180244
MESH:D019584 Hot Flashes Estradiol 7.6517088409
MESH:D019584 Hot Flashes Vitamin E 7.6514716179
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.3218606429 8697196 16354765 15340226 16959395
MESH:D006930 Hyperalgesia Acetaminophen 5.7116870215
MESH:D006930 Hyperalgesia Tretinoin 5.7116870215
MESH:D006937 Hypercholesterolemia Dietary Fats 2.9521332399
MESH:D006940 Hyperemia Hydrochloric Acid 4.9412646421
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 3.8716778211
MESH:D006943 Hyperglycemia pirinixic acid 2.5620558911
MESH:D017488 Hyperkeratosis, Epidermolytic Arsenic 3.8217050553
MESH:D006948 Hyperkinesis Clozapine 4.2016046005
MESH:D006949 Hyperlipidemias Dietary Fats 2.9621332399
MESH:D006973 Hypertension Arsenic 12.8216076760 9931084 11953799
MESH:D006973 Hypertension Benzene 12.8217940673
MESH:D006973 Hypertension Cyclosporine 12.8210903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 12.8218670907 18850075
MESH:D006973 Hypertension valsartan 12.8216475468 20102058 11427623 18344623 12692753 12850387 18390891 10903974
MESH:D006974 Hypertension, Malignant valsartan 5.6811560862
MESH:D006975 Hypertension, Portal Hydrochloric Acid 4.6516984587
MESH:D006976 Hypertension, Pulmonary Hydrochloric Acid 3.9219262391
MESH:D006980 Hyperthyroidism Methimazole 4.9314678291
MESH:D017379 Hypertrophy, Left Ventricular tanshinone 4.6119662366
MESH:D006987 Hypesthesia Arsenic 4.8316093927
MESH:D007021 Hypospadias Ethinyl Estradiol 3.1116945680 16569931
MESH:D007022 Hypotension Hydrochloric Acid 4.1011574821
MESH:D007037 Hypothyroidism Methimazole 9.6418031379
MESH:D007037 Hypothyroidism Propylthiouracil 9.648137927 18031379
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 3.7015869954
MESH:D007247 Infertility, Female Ethinyl Estradiol 2.8012013081
MESH:D007248 Infertility, Male decitabine 11.9117581917
MESH:D007248 Infertility, Male Ethinyl Estradiol 11.9117937319
MESH:D007248 Infertility, Male methyl cellosolve 11.913987992
MESH:D007248 Infertility, Male sodium arsenite 11.9112646999 15346721
MESH:D007249 Inflammation Dietary Fats 11.3720412841
MESH:D007249 Inflammation Hydrochloric Acid 11.3711574821
MESH:D007249 Inflammation Progesterone 11.3715869954
MESH:D007249 Inflammation Tamoxifen 11.3719457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 11.3712878042 12200463
MESH:D007251 Influenza, Human Selenium 8.5516624496
MESH:D007251 Influenza, Human Vitamin E 8.5516624496
MESH:D007333 Insulin Resistance Dietary Fats 9.3718457598 11836018
MESH:D007333 Insulin Resistance Estradiol 9.3716627594 16393666
MESH:D007333 Insulin Resistance pirinixic acid 9.3716306350
MESH:D007410 Intestinal Diseases Hydrochloric Acid 7.8211574821
MESH:D007410 Intestinal Diseases Tretinoin 7.8217994277
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 7.7916580747
MESH:D007569 Jaw Abnormalities Tretinoin 7.7915992940 17551590
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 3.7115604871
MESH:D007642 Keratosis Arsenic 4.2812749816 16930632
MESH:D007674 Kidney Diseases Acetaminophen 25.9115629191 12587719
MESH:D007674 Kidney Diseases Cadmium Chloride 25.9116962696
MESH:D007674 Kidney Diseases Cyclosporine 25.9118776723 10903974 8314463
MESH:D007674 Kidney Diseases Doxorubicin 25.9115369732 15699352 16775033
MESH:D007674 Kidney Diseases Estradiol 25.9115618244
MESH:D007674 Kidney Diseases sodium arsenite 25.9120008137
MESH:D007674 Kidney Diseases valsartan 25.9112164870 10903974 16893502
MESH:D007674 Kidney Diseases Vitamin E 25.9112488133
MESH:D007676 Kidney Failure, Chronic Doxorubicin 7.8416707910
MESH:D007676 Kidney Failure, Chronic Selenium 7.8416518626
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 17.0916705839
MESH:D007680 Kidney Neoplasms Cyclosporine 17.0912371664
MESH:D007680 Kidney Neoplasms Estradiol 17.0915610895
MESH:D007680 Kidney Neoplasms Fluorouracil 17.0916985049
MESH:D007680 Kidney Neoplasms Tamoxifen 17.0918625569
MESH:D007818 Laryngeal Diseases Hydrochloric Acid 5.6316498863
MESH:D007826 Laryngismus Hydrochloric Acid 5.6311510729
MESH:D007859 Learning Disorders sevoflurane 4.0819212262
MESH:D007938 Leukemia arsenic trioxide 11.5915070760
MESH:D007938 Leukemia Benzene 11.5918335105 17119257 14694614 15935818
MESH:D007938 Leukemia decitabine 11.5919235587 18980019
MESH:D007938 Leukemia Tretinoin 11.5917143497
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 4.4316085563
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.1517077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 3.5916972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 2.8814633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 17.5619077051
MESH:D007951 Leukemia, Myeloid Benzene 17.5617506065
MESH:D007951 Leukemia, Myeloid decitabine 17.5617236224 19117987 18454857
MESH:D007951 Leukemia, Myeloid Tretinoin 17.5616932348 16482212 19285840
MESH:D015470 Leukemia, Myeloid, Acute marker/mechanism 17330099
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 7.1716467208 17050201 19850784 16968895 20471514
MESH:D015470 Leukemia, Myeloid, Acute Benzene 7.1719478238
MESH:D015470 Leukemia, Myeloid, Acute decitabine 7.1718206229 17679729 19387464 19010910 18704418 18460780
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 7.1716294345 17596541 19850784
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 4.7318055864
MESH:D015473 Leukemia, Promyelocytic, Acute Arsenic 9.8517339181
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 9.8516112521 12679006 17712046 16966277 19642359 17217047 11468182 11161223 15213294 17869043 19035177 16330433 16891316 15622746 12712474 19225113 17649720 12018890 16823087 15336539 17107899 16331271 9834237 15748426 19075265
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 9.8517368321 16891316 17217047 17712046 19225113 17649720 17301526 16823087 19029980 19642359 16766008 19035177 16935935 9834237 16140955 19075265 16331271 17294898 12679006 17107899 15748426 16788101 17506722 17339181 17361223
MESH:D015458 Leukemia, T-Cell arsenic trioxide 3.6716882451
MESH:D017880 Limb Deformities, Congenital methyl cellosolve 6.776499821
MESH:D017880 Limb Deformities, Congenital Tretinoin 6.779224671
MESH:D008064 Lipidoses Clozapine 6.2917567588
MESH:D008064 Lipidoses Tamoxifen 6.2917567588 15342952
MESH:D008103 Liver Cirrhosis Dietary Fats 8.6118296743
MESH:D008103 Liver Cirrhosis Hydrochloric Acid 8.6116984587
MESH:D008103 Liver Cirrhosis Phenobarbital 8.6121047994
MESH:D008106 Liver Cirrhosis, Experimental therapeutic 17127702
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 17.4816595196 16439617
MESH:D008106 Liver Cirrhosis, Experimental epigallocatechin gallate 17.4817481882
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 17.4814716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Fenofibrate 17.4815474484
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 17.4815474484
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 17.4818564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 17.4812878042
MESH:D008106 Liver Cirrhosis, Experimental Thioacetamide 17.4816489207 15078482 11481614 15474484 18416461 11682029 17127702 15716488 18395095 16126171 16098781 18031379 12557150 17355460 12531686 17292413 15362042 15095483 12891558 15158331 17050028 15288472 15075984 16248980 16097051 16343077 14739098 18458672 10677585 18295389 12175628 17629604 12085344 18032466 18380797 15316131 15334695 11172339 12679928 18615449 15465738 15288473 18606216 16511523 18263696
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 17.4816248980 18397230
MESH:D008106 Liver Cirrhosis, Experimental valsartan 17.4815504291 15619341 16872305
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 17.4816169303
MESH:D008107 Liver Diseases Acetaminophen 7.3216611625 16610002 19014921 12587719 12969438 11587558 19460945 19784758
MESH:D008107 Liver Diseases Arsenic 7.3211134558
MESH:D008107 Liver Diseases Phenobarbital 7.3219363144
MESH:D008107 Liver Diseases Thioacetamide 7.3218374380 15158337 16337175
MESH:D017114 Liver Failure, Acute Acetaminophen 7.5517185352 16871587
MESH:D017114 Liver Failure, Acute Thioacetamide 7.5515633222 17276928 12479984 15313186
MESH:D008113 Liver Neoplasms Arsenic 23.4016368122
MESH:D008113 Liver Neoplasms arsenic trioxide 23.4014682389
MESH:D008113 Liver Neoplasms Fenofibrate 23.4018978307
MESH:D008113 Liver Neoplasms Fluorouracil 23.4015113037 17045692 18383874 16603448
MESH:D008113 Liver Neoplasms Phenobarbital 23.4019812893 15975961 19073162 8742319 21047994 19482888
MESH:D008113 Liver Neoplasms pirinixic acid 23.4020007298 16377806 15890375
MESH:D008113 Liver Neoplasms sodium arsenite 23.4016712894 15276417
MESH:D008113 Liver Neoplasms Tamoxifen 23.4016684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 23.4016984957
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 24.7620377131
MESH:D008114 Liver Neoplasms, Experimental Benzene 24.7612562636
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 24.7616842330 17085340
MESH:D008114 Liver Neoplasms, Experimental Fenofibrate 24.7618253720 18775883
MESH:D008114 Liver Neoplasms, Experimental Methylcholanthrene 24.76598648 1399818
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 24.762563599 1399818 6150874 17172636 18308698
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 24.7612151625
MESH:D008114 Liver Neoplasms, Experimental Trichloroethylene 24.767955063
MESH:D008133 Long QT Syndrome arsenic trioxide 2.7915213294
MESH:D008171 Lung Diseases Acetylcysteine 17.6812815614
MESH:D008171 Lung Diseases Hydrochloric Acid 17.6816784557
MESH:D008171 Lung Diseases Ozone 17.688266340 19066396
MESH:D008171 Lung Diseases sodium arsenite 17.6819095001
MESH:D008171 Lung Diseases Vitamin E 17.6816863852
MESH:D017563 Lung Diseases, Interstitial Benzene 4.0814698565
MESH:D055370 Lung Injury Hydrochloric Acid 11.4215090967 18339021 21114838 15044056 11395602 16129981 19644408 18573544 19262391 18497604 21311175 17627322 20597076 15607125
MESH:D055370 Lung Injury Oxygen 11.4218339021
MESH:D055370 Lung Injury Ozone 11.4220417186
MESH:D008175 Lung Neoplasms Arsenic 17.1619168569 17976673 17306315
MESH:D008175 Lung Neoplasms arsenic trioxide 17.1619825857 11798837
MESH:D008175 Lung Neoplasms Benzene 17.1612562636
MESH:D008175 Lung Neoplasms Doxorubicin 17.166189445 17418594
MESH:D008175 Lung Neoplasms Fluorouracil 17.1615246190
MESH:D008175 Lung Neoplasms Methylcholanthrene 17.161399818 10545420 9230183 17909032 16337739 11893704 16271038 21163286 7750092 6695378 15390079 20512841 20970405
MESH:D008175 Lung Neoplasms Ozone 17.167614698 8597069
MESH:D008175 Lung Neoplasms sodium arsenite 17.1616712894 17077188 17306315 15276417 19931552
MESH:D008175 Lung Neoplasms Tamoxifen 17.1618625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 17.1619555203 11884234
MESH:D008175 Lung Neoplasms Vitamin E 17.1611062179
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.0815086387
MESH:D008223 Lymphoma Benzene 9.5617119257 17584886
MESH:D008223 Lymphoma decitabine 9.5619470736
MESH:D008223 Lymphoma Doxorubicin 9.5616098063
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 3.2017654614
MESH:D016399 Lymphoma, T-Cell Doxorubicin 3.8715621674
MESH:D016410 Lymphoma, T-Cell, Cutaneous vorinostat 4.9920479100
MESH:D008231 Lymphopenia methyl cellosolve 5.073699323
MESH:D015674 Mammary Neoplasms, Animal Benzene 7.7212562636
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 7.7219428831
MESH:D008325 Mammary Neoplasms, Experimental Benzene 17.1611921183
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 17.1615458769
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 17.1611807958 17203775 16891317 11408345
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 17.1617203775 11408345
MESH:D008325 Mammary Neoplasms, Experimental Selenium 17.1615318939
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 17.1614580682 19196723 11731420 19196722 16827153
MESH:D020149 Manganese Poisoning Estradiol 18.2019453300
MESH:D020149 Manganese Poisoning Manganese 18.2016568477 16551646 19453300
MESH:D020149 Manganese Poisoning Tamoxifen 18.2019453300
MESH:D008527 Medulloblastoma Tretinoin 2.4517453147
MESH:D008545 Melanoma decitabine 12.4916505122 17785578
MESH:D008545 Melanoma Doxorubicin 12.4916827129
MESH:D008545 Melanoma epigallocatechin gallate 12.4911746506 17992120
MESH:D008545 Melanoma sodium arsenite 12.4916487513 19082730
MESH:D008545 Melanoma Tamoxifen 12.4912393984 19393235
MESH:D008545 Melanoma Tretinoin 12.4916752155
MESH:D008545 Melanoma Vinblastine 12.4912374674 17761969 18332650 16809738 18176117 15577323 15577320 16248763 18505091 16432458
MESH:D018328 Melanoma, Amelanotic Tamoxifen 3.4715990972
MESH:D008546 Melanoma, Experimental Acetaminophen 2.8719513568
MESH:D008569 Memory Disorders sevoflurane 4.0819212262
MESH:D008591 Meningomyelocele Tretinoin 3.7316940565
MESH:D001523 Mental Disorders Clozapine 6.0516856516
MESH:D001523 Mental Disorders Haloperidol 6.0516856516
MESH:D008654 Mesothelioma Doxorubicin 5.1317638057
MESH:D008654 Mesothelioma Selenium 5.1315107826
MESH:D024821 Metabolic Syndrome X Clozapine 3.8119142101
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.0616801185
MESH:D008679 Metaplasia Ozone 4.3810496685
MESH:D008708 Methemoglobinemia Nitroglycerin 4.083537620
MESH:D020326 Migraine without Aura Nitroglycerin 4.4514659530
MESH:D028361 Mitochondrial Diseases Doxorubicin 3.8515792986
MESH:D009062 Mouth Neoplasms Fluorouracil 3.0716757204 18986760
MESH:D009069 Movement Disorders Manganese 4.3516551646
MESH:D052016 Mucositis Doxorubicin 10.0517415656
MESH:D052016 Mucositis irinotecan 10.0517159606
MESH:D009101 Multiple Myeloma arsenic trioxide 9.1019417148 14977855 15949261 19549372 11468182
MESH:D009101 Multiple Myeloma Benzene 9.1017119195
MESH:D009101 Multiple Myeloma decitabine 9.1018172295
MESH:D009134 Muscular Atrophy, Spinal epigallocatechin gallate 4.7817962980
MESH:D009135 Muscular Diseases pirinixic acid 2.8116239165
MESH:D009139 Musculoskeletal Abnormalities sodium arsenate 4.2118186108
MESH:D009182 Mycosis Fungoides arsenic trioxide 3.9418349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 9.6916882451 16105982
MESH:D009190 Myelodysplastic Syndromes decitabine 9.6919157545 16882708 19010910 18608210
MESH:D009190 Myelodysplastic Syndromes Tretinoin 9.6917596541
MESH:D009203 Myocardial Infarction Doxorubicin 10.6815857846 19429709
MESH:D009203 Myocardial Infarction Hydrochloric Acid 10.6818534312
MESH:D009203 Myocardial Infarction Nitroglycerin 10.6814729435
MESH:D009203 Myocardial Infarction pirinixic acid 10.6819151258
MESH:D017202 Myocardial Ischemia Arsenic 7.0615371236
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 7.0612213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 6.3616810080
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 6.3616411023
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 3.7617484760
MESH:D009325 Nausea vorinostat 4.8020479100
MESH:D009336 Necrosis 2,4-dinitrotoluene 3.1518551238
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.2816624393
MESH:D009362 Neoplasm Metastasis Acetylcysteine 10.7714720322
MESH:D009362 Neoplasm Metastasis Doxorubicin 10.7718259882
MESH:D009362 Neoplasm Metastasis irinotecan 10.7718259882
MESH:D009362 Neoplasm Metastasis Tamoxifen 10.7719393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.2319410462
MESH:D009369 Neoplasms decitabine 14.4817925555 19116145 19470736
MESH:D009369 Neoplasms Fluorouracil 14.4816928823 18600527 18239605
MESH:D009369 Neoplasms pirinixic acid 14.4817405874
MESH:D009369 Neoplasms sodium arsenite 14.4811559025
MESH:D009369 Neoplasms Tretinoin 14.4816594593 16946489
MESH:D009369 Neoplasms Trichloroethylene 14.4811911487
MESH:D009374 Neoplasms, Experimental sodium arsenite 2.9820056578
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.2819200415 19189210 19196722
MESH:D009389 Neovascularization, Pathologic Estradiol 3.0317289903
MESH:D009401 Nephrosis Doxorubicin 4.0716636307 16899518
MESH:D009402 Nephrosis, Lipoid Cyclosporine 3.7117954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 7.2618481113 19348381
MESH:D009404 Nephrotic Syndrome Doxorubicin 7.2616889571 15640375
MESH:D009410 Nerve Degeneration Manganese 3.7116551646
MESH:D009421 Nervous System Malformations Estradiol 12.4211399458 16427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 12.4214600291
MESH:D009421 Nervous System Malformations Tretinoin 12.429125849
MESH:D009436 Neural Tube Defects Acetylcysteine 26.5419446573
MESH:D009436 Neural Tube Defects Arsenic 26.5416620997
MESH:D009436 Neural Tube Defects arsenic trioxide 26.5410525206
MESH:D009436 Neural Tube Defects Benzene 26.5415643154
MESH:D009436 Neural Tube Defects sodium arsenate 26.5419446573 10525206 11749123 18186108
MESH:D009436 Neural Tube Defects sodium arsenite 26.5412854658
MESH:D009436 Neural Tube Defects Tretinoin 26.549142499
MESH:D009447 Neuroblastoma Doxorubicin 5.7515555623
MESH:D009447 Neuroblastoma irinotecan 5.758761367
MESH:D019636 Neurodegenerative Diseases Acetaminophen 2.2818514411
MESH:D017599 Neuroectodermal Tumors irinotecan 4.028761367
MESH:D020078 Neurogenic Inflammation Arsenic 3.7117056641
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 2.9316436463
MESH:D009503 Neutropenia Vinblastine 3.9217378895
MESH:D009765 Obesity Clozapine 6.0418515891 19142110
MESH:D009765 Obesity Dietary Fats 6.0417217161 18674790 21332399 20132043 11836018 20518802 16723640 19632207 18457598
MESH:D009765 Obesity pirinixic acid 6.0420558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 11.7312819281 16049721
MESH:D009784 Occupational Diseases Benzene 11.7315576619 15727169 17178637 15612468 17119257 15935809 17479406 16737584 15913788
MESH:D009784 Occupational Diseases Hydrochloric Acid 11.7312378975
MESH:D009845 Oligospermia methyl cellosolve 4.473987992
MESH:D010018 Osteomalacia Phenobarbital 3.6517016548
MESH:D012516 Osteosarcoma Doxorubicin 3.5315930896
MESH:D010051 Ovarian Neoplasms Arsenic 21.9617306315
MESH:D010051 Ovarian Neoplasms arsenic trioxide 21.9612452020 19769630 16624393
MESH:D010051 Ovarian Neoplasms Benzene 21.9612562636
MESH:D010051 Ovarian Neoplasms decitabine 21.9619331143 19259094
MESH:D010051 Ovarian Neoplasms Estradiol 21.9619401270
MESH:D010051 Ovarian Neoplasms Progesterone 21.9616525653 17393432
MESH:D010051 Ovarian Neoplasms sodium arsenite 21.9617306315 15276417
MESH:D010051 Ovarian Neoplasms Tretinoin 21.9616936753
MESH:D010146 Pain Acetaminophen 4.6616870215
MESH:D010146 Pain Tretinoin 4.6616870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 12.8715580305
MESH:D010190 Pancreatic Neoplasms decitabine 12.8719294695
MESH:D010190 Pancreatic Neoplasms Fluorouracil 12.8719003803 16929163 15113037 16500647
MESH:D010190 Pancreatic Neoplasms Phenobarbital 12.8716965848
MESH:D010190 Pancreatic Neoplasms Tretinoin 12.8715976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.0211578682
MESH:D010235 Paraganglioma arsenic trioxide 3.5019927285
MESH:D010300 Parkinson Disease Manganese 3.0711181820
MESH:D020734 Parkinsonian Disorders Manganese 3.8516140633
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.5212520081
MESH:D010523 Peripheral Nervous System Diseases Arsenic 3.5016093927
MESH:D016491 Peripheral Vascular Diseases Arsenic 4.2815371236 6392382 16905509
MESH:D010538 Peritonitis Ozone 3.4416369182
MESH:D003557 Phyllodes Tumor Doxorubicin 4.4317983394
MESH:D010954 Plasmacytoma Selenium 4.1615087411
MESH:D010997 Pleural Neoplasms Doxorubicin 4.4317638057
MESH:D011014 Pneumonia Ozone 3.6818381685 18929643 18007984
MESH:D011015 Pneumonia, Aspiration Hydrochloric Acid 4.6615970105 18497604 18573544 15607125
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 2.8818163543
MESH:D011230 Precancerous Conditions Cyclosporine 6.9412371664
MESH:D011230 Precancerous Conditions Phenobarbital 6.942563599
MESH:D011297 Prenatal Exposure Delayed Effects methyl cellosolve 7.5212530607 7974496 6499817
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 7.5211118676 11399792 11222880 11896295
MESH:D055728 Primary Myelofibrosis decitabine 4.0317616702
MESH:D011470 Prostatic Hyperplasia Calcitriol 4.0715572423
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.2420887781
MESH:D011471 Prostatic Neoplasms Arsenic 3.6116140617
MESH:D011471 Prostatic Neoplasms arsenic trioxide 3.6119131511
MESH:D011471 Prostatic Neoplasms Calcitriol 3.6116644109 16289102 12479363 15754350 18247401
MESH:D011471 Prostatic Neoplasms Doxorubicin 3.6116888761 15897917 15749863 18437689 16868541 16729912
MESH:D011471 Prostatic Neoplasms Estradiol 3.6116740699
MESH:D011471 Prostatic Neoplasms Fluorouracil 3.6119082440 18626508
MESH:D011471 Prostatic Neoplasms methylselenic acid 3.6116205645
MESH:D011471 Prostatic Neoplasms sodium arsenite 3.6116039940
MESH:D011471 Prostatic Neoplasms Tamoxifen 3.6115067354
MESH:D011471 Prostatic Neoplasms Vitamin E 3.6115084515
MESH:D011471 Prostatic Neoplasms vorinostat 3.6117218635
MESH:D011507 Proteinuria Arsenic 11.7921343184
MESH:D011507 Proteinuria Tretinoin 11.7916636307
MESH:D011507 Proteinuria valsartan 11.7917664856 12164870 18344623
MESH:D011537 Pruritus Ethinyl Estradiol 2.6115861022 16919318
MESH:D019310 Pseudolymphoma Phenobarbital 3.7712752131
MESH:D011565 Psoriasis Cyclosporine 1.9316882103
MESH:D011595 Psychomotor Agitation Haloperidol 4.2611575062
MESH:D011618 Psychotic Disorders Clozapine 7.3515331141
MESH:D011618 Psychotic Disorders Haloperidol 7.3511575062
MESH:D011625 Pterygium Tretinoin 4.0816723453
MESH:D001261 Pulmonary Atelectasis Hydrochloric Acid 5.2920597076
MESH:D011654 Pulmonary Edema Hydrochloric Acid 4.4915090967
MESH:D011658 Pulmonary Fibrosis valsartan 3.4917241526
MESH:D012004 Rectal Neoplasms Fluorouracil 3.4018286688 15538739 18722050 16160472
MESH:D051437 Renal Insufficiency Doxorubicin 3.5317922066
MESH:D015427 Reperfusion Injury pirinixic acid 1.9919058328
MESH:D012120 Respiration Disorders Chlorine 4.4918579056
MESH:D012128 Respiratory Distress Syndrome, Adult Acetylcysteine 11.7012210543
MESH:D012128 Respiratory Distress Syndrome, Adult Hydrochloric Acid 11.7017627322 18339021 16784557 18549715 16129981
MESH:D012128 Respiratory Distress Syndrome, Adult Oxygen 11.7018339021 17627322
MESH:D012133 Respiratory Paralysis Hydrochloric Acid 5.6311510729
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.1618990726
MESH:D012140 Respiratory Tract Diseases Hydrochloric Acid 4.4420516732
MESH:D012208 Rhabdomyosarcoma decitabine 8.7419155313
MESH:D012208 Rhabdomyosarcoma Tretinoin 8.7416116481 16283617
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.5518045962
MESH:D012509 Sarcoma Doxorubicin 3.3615625365 17203757 16767912 17710206 18313854 15675481
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 8.0216646077
MESH:D012512 Sarcoma, Ewing's Doxorubicin 8.0216326096 14601052
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.0817846226
MESH:D012559 Schizophrenia Clozapine 3.5920168265 20580759 16141801 20452607 17667964 11763009 18806925 20521326 17123785 18855531 11151749 17726453 19369910 20107430 20521320
MESH:D012559 Schizophrenia Haloperidol 3.591830565 19369910 20107430 18513383
MESH:D012640 Seizures 2,4-dinitrotoluene 4.2518551238
MESH:D012640 Seizures Phenobarbital 4.253137016 4039156 16876388 11442880
MESH:D003294 Seizures, Febrile Phenobarbital 4.116407741
MESH:D012871 Skin Diseases marker/mechanism 16835338
MESH:D012871 Skin Diseases Arsenic 4.2117938729 19834688 17548696 16759981 18709164 16702368 15952646 16353154 17050553 17453740 6392382
MESH:D012871 Skin Diseases Vitamin E 4.2118709164
MESH:D012878 Skin Neoplasms Arsenic 17.3517029826 16251483 17976673 15504454 19538983 17050553
MESH:D012878 Skin Neoplasms Doxorubicin 17.3515692506
MESH:D012878 Skin Neoplasms sodium arsenite 17.3518572023 19524636
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 17.358532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 17.3516192470
MESH:D012878 Skin Neoplasms Tretinoin 17.3516467112
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 3.8717203757 16767912 15625365
MESH:D013088 Spermatocele Ethinyl Estradiol 9.1516709447
MESH:D013088 Spermatocele Tamoxifen 9.1516709447
MESH:D013119 Spinal Cord Injuries Progesterone 8.5115862959 16503802
MESH:D013119 Spinal Cord Injuries Tamoxifen 8.5119457130
MESH:D016135 Spinal Dysraphism sodium arsenite 3.2212854658
MESH:D013274 Stomach Neoplasms arsenic trioxide 6.8217007042
MESH:D013274 Stomach Neoplasms Benzene 6.8212562636
MESH:D013274 Stomach Neoplasms decitabine 6.8219037991
MESH:D013274 Stomach Neoplasms Fluorouracil 6.8216424979 15786421 17522103 19084572 18396642 19015929 17172411 17498489 18567086 16951190
MESH:D013274 Stomach Neoplasms irinotecan 6.8215723263
MESH:D013274 Stomach Neoplasms Tretinoin 6.8217261132
MESH:D013276 Stomach Ulcer Acetylcysteine 5.9017918041
MESH:D013276 Stomach Ulcer Hydrochloric Acid 5.9015309881 17189318 16755016
MESH:D020521 Stroke Vitamin E 2.9416517955
MESH:D013398 Sudden Infant Death Oxygen 4.8312563064
MESH:D017180 Tachycardia, Ventricular Haloperidol 4.0320210726
MESH:D013733 Testicular Diseases methyl cellosolve 4.386499806
MESH:D013921 Thrombocytopenia vorinostat 4.3420479100
MESH:D019851 Thrombophilia Ethinyl Estradiol 2.9611994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.5415669648
MESH:D013953 Thymus Neoplasms Benzene 4.2410850423
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 9.9612697716
MESH:D013959 Thyroid Diseases Thyroxine 9.9619910387
MESH:D013964 Thyroid Neoplasms arsenic trioxide 25.2219014326
MESH:D013964 Thyroid Neoplasms Butyrates 25.2217967635
MESH:D013964 Thyroid Neoplasms decitabine 25.2217967635
MESH:D013964 Thyroid Neoplasms Doxorubicin 25.2217909728 16010429
MESH:D013964 Thyroid Neoplasms Phenobarbital 25.221399818
MESH:D013964 Thyroid Neoplasms Propylthiouracil 25.2215710170
MESH:D013964 Thyroid Neoplasms Tretinoin 25.2216026305 17045167
MESH:D013978 Tibial Fractures Estradiol 3.9619048282
MESH:D014062 Tongue Neoplasms Fluorouracil 7.7416280240
MESH:D014062 Tongue Neoplasms Tretinoin 7.7416051514
MESH:D016171 Torsades de Pointes arsenic trioxide 3.2515213294
MESH:D014376 Tuberculosis Tretinoin 2.7416040207
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 18.8316049721
MESH:D001749 Urinary Bladder Neoplasms Arsenic 18.8317976673 17306315 19322015 19429237 11144890 15987713 18640142
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 18.8312973940 20435036 11780464 12845720
MESH:D001749 Urinary Bladder Neoplasms decitabine 18.8317616700 19087683
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 18.8317653716
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 18.8317306315 11723127 16712894 16452187
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 18.8316712894 17572228 8653321
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 3.6010091137
MESH:D014581 Urticaria Acetaminophen 2.3310982225
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 12.2316803524
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 12.2311813266
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 12.2316129372
MESH:D014594 Uterine Neoplasms Benzene 7.3212562636
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 7.3214692618
MESH:D014604 Uveal Neoplasms decitabine 10.4117785578
MESH:D014604 Uveal Neoplasms Tretinoin 10.4116752155
MESH:D014605 Uveitis Cyclosporine 3.261336536
MESH:D014625 Vaginal Neoplasms Vinblastine 4.3515577323
MESH:D014652 Vascular Diseases Arsenic 9.4817056641
MESH:D014652 Vascular Diseases sodium arsenite 9.4817056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 3.8712125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 2.8914671159 15869587
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 3.5317678736 17638931 17334414 16364871
MESH:D020257 Ventricular Remodeling valsartan 4.9819027736
MESH:D014820 Vitiligo Tretinoin 3.3816761959
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.5215886252
MESH:D015430 Weight Gain Clozapine 7.7920521320 20107430 20564506 17502770 16402076 16141801
MESH:D015430 Weight Gain Dietary Fats 7.7916723640
MESH:D015431 Weight Loss Clozapine 4.3617933447
MESH:D009396 Wilms Tumor Tretinoin 3.3516287080
MESH:D014985 Xerophthalmia Cyclosporine 3.7117120751
Pathway ID Pathway Name
KEGG:04350 TGF-beta signaling pathway
Pharmacogenomics Knowledge Base Top
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Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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