AutismKB 2.0

Annotation Detail for APOC1


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Basic Information Top
Gene Symbol:APOC1 ( - )
Gene Full Name: apolipoprotein C-I
Band: 19q13.32
Quick LinksEntrez ID:341; OMIM: 107710; Uniprot ID:APOC1_HUMAN; ENSEMBL ID: ENSG00000130208; HGNC ID: 607
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1703Fatty liver
1740Alzheimer's disease
1904Diabetes mellitus
1918Atherosclerosis
2070Cholelithiasis
2097Hyperlipidemia
2106Pancreas cancer
2111Systemic infection
2220Dermatitis
Desease Name
cardiovascular disease
AGING
atherosclerosis, coronary
C-reactive protein
CARDIOVASCULAR
cholesterol, LDL
Alzheimer's disease
high and low levels of cholesterol
lipoprotein
NEUROLOGICAL
quantitative traits
METABOLIC
LDL cholesterol
obesity
Age-associated memory impairment
gallstones
Desease Name
Lipoprotein-associated phospholipase A2 activity and mass
LDL cholesterol
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of APOC1 proteinaffects expression 20106945
C040534 alpha-hexachlorocyclohexane alpha-hexachlorocyclohexane results in decreased expression of APOC1 mRNAdecreases expression 16940010
D000643 Ammonium Chloride Ammonium Chloride affects the expression of APOC1 mRNAaffects expression 16483693
D016718 Arachidonic Acid Arachidonic Acid results in decreased expression of APOC1 mRNAdecreases expression 16623957
C095105 bexarotene bexarotene results in decreased expression of APOC1 mRNAdecreases expression 16648578
C006780 bisphenol A bisphenol A results in decreased expression of APOC1 mRNAdecreases expression 12075121
D002211 Capsaicin Capsaicin results in decreased expression of APOC1 mRNAdecreases expression 18533110
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of APOC1 mRNAaffects expression 15963342
D002251 Carbon Tetrachloride Carbon Tetrachloride results in decreased expression of APOC1 mRNAdecreases expression 16239168
D016572 Cyclosporine Cyclosporine results in decreased expression of APOC1 mRNAdecreases expression 20106945
C121718 dicyclanil dicyclanil results in increased expression of APOC1 mRNAincreases expression 15664270
D004041 Dietary Fats Dietary Fats results in decreased expression of APOC1 mRNAdecreases expression 18042831
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of APOC1 mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of APOC1 mRNAdecreases expression 16174780
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of APOC1 mRNAaffects expression 17351261
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of APOC1 mRNAdecreases expression 12075121
16174780
D005472 Fluorouracil APOC1 protein affects the susceptibility to Fluorouracilaffects response to substance 16217747
C039281 furan furan results in decreased expression of APOC1 mRNAdecreases expression 15120968
D019833 Genistein Genistein results in decreased expression of APOC1 mRNAdecreases expression 12075121
D018684 Glycine Agents Glycine Agents results in increased expression of APOC1 mRNAincreases expression 16532367
C029424 hydrazine hydrazine results in decreased expression of APOC1 mRNAdecreases expression 15370871
D008701 Methapyrilene Methapyrilene results in decreased expression of APOC1 mRNAdecreases expression 15120968
D015735 Mifepristone Mifepristone results in decreased expression of APOC1 mRNAdecreases expression 17584828
C041786 palm oil palm oil results in decreased expression of APOC1 mRNAdecreases expression 18042831
D013629 Tamoxifen Tamoxifen affects the expression of APOC1 mRNAaffects expression 17555576
C021751 tanshinone tanshinone results in increased expression of APOC1 mRNAincreases expression 15849732
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of APOC1 mRNAincreases expression 20106945
11489354
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of APOC1 mRNAincreases expression 15703262
16267337
D013752 Tetracycline Tetracycline results in decreased expression of APOC1 mRNAdecreases expression 16917069
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.3814745880
MESH:D000014 Abnormalities, Drug-Induced Capsaicin 8.1218926900
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 8.1211752688 14514962 15322242
MESH:D000138 Acidosis Ammonium Chloride 3.3918287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.7717505938
MESH:D058186 Acute Kidney Injury Capsaicin 4.3918460982
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 6.8514692618
MESH:D000230 Adenocarcinoma Fluorouracil 6.8517638652
MESH:D000230 Adenocarcinoma Genistein 6.8511473722
MESH:D018248 Adenoma, Liver Cell dicyclanil 9.9217162532
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 9.9216835633
MESH:D000505 Alopecia Capsaicin 4.5917569567
MESH:D000740 Anemia Fluorouracil 8.1816511603 15504547 17963324
MESH:D000740 Anemia Tetrachlorodibenzodioxin 8.1811748828
MESH:D001161 Arteriosclerosis Dietary Fats 9.3415238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 9.3411256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.5615885639
MESH:D001321 Autistic Disorder Arachidonic Acid 3.0418582451
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 2.8912125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.6215340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.6515746008
MESH:D001862 Bone Resorption bisphenol A 3.7111985600
MESH:D001919 Bradycardia Capsaicin 4.8818207255
MESH:D002545 Brain Ischemia Capsaicin 4.8019211983
MESH:D001943 Breast Neoplasms bexarotene 4.6016818667 16344269
MESH:D001943 Breast Neoplasms bisphenol A 4.6017123778
MESH:D001943 Breast Neoplasms Dietary Fats 4.6020435547
MESH:D001943 Breast Neoplasms Fluorouracil 4.6018357371 19217205 16110121 15136595 18608205 16595493 16557594
MESH:D001943 Breast Neoplasms Genistein 4.6016873071 17200150 16541309
MESH:D001943 Breast Neoplasms Tamoxifen 4.6019059307 19189210 11161223 18351453 19155303 17893378 16818667 18815881 19244106 18855134 20065188 18629630 20135344 19221464 18821012 16202921 18997820 19011961 19103187 19142967 17242785 19084267 18984771 19189212 19066611 18425577 20005174 19410462 16273361 20390343 19200415 19115204 19289846 15565566 19487384 17261762 20859285 20544844 17049068 21152245 19288272 15668708 16873071 21138602 17440819
MESH:D001943 Breast Neoplasms tanshinone 4.6015849732 19885617
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 4.6020435547
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.6116097048 16011737 18705752 16192424 15700767 10355542 15673190 16124888 16227642 3786805 15721981 16050911
MESH:D002276 Carcinoid Tumor Fluorouracil 4.5016051944
MESH:D002277 Carcinoma Fluorouracil 7.7317121937
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 7.7316835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.3419066611
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 11.0312907637 12619106 21507988
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 11.0318788625
MESH:D006528 Carcinoma, Hepatocellular dicyclanil 11.0317162532
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 11.0318930000 17971768 16332177 17045692 16799960 17088986
MESH:D006528 Carcinoma, Hepatocellular Genistein 11.0316924424
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 11.0316924424
MESH:D002278 Carcinoma in Situ bisphenol A 4.8217123778
MESH:D002289 Carcinoma, Non-Small-Cell Lung bexarotene 3.1716247446
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 2.9418695887
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 2.4416757204 18986760 17066447 16280240
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.4617572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.2718850075 16120746 18670907
MESH:D002318 Cardiovascular Diseases Genistein 3.1916332659
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 2.4112371664
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.0216835633
MESH:D002779 Cholestasis Cyclosporine 7.3619486331
MESH:D002779 Cholestasis Ethinyl Estradiol 7.3616105132 11677210 16919318 17110522 17333356 17681005 15861022
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.0312621046 15668235 16354765 15340226 8697196
MESH:D003110 Colonic Neoplasms Fluorouracil 3.7417016597 15001691 17287894 16510598 17169374 17725105 17018589 18772588 16340194 17172411
MESH:D003110 Colonic Neoplasms Genistein 3.7417182828
MESH:D015179 Colorectal Neoplasms Fluorouracil 2.0016524972 17255274 18383874 17594712 17695437 18949393 20501625 18288408 16282729 15289873 18802399 17016601 16331619 16391804 17454858 18448328 15148649 17094418 16303861 14970324 18509181 17401013
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.9114669216 17141729
MESH:D003371 Cough Capsaicin 5.0010350223
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 1.2520055451 15322242 10048152
MESH:D007644 Darier Disease Fluorouracil 4.6216733453
MESH:D003711 Demyelinating Diseases Tamoxifen 4.1919031437
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 4.1916647724
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.1917107852
MESH:D003928 Diabetic Nephropathies Tamoxifen 3.3319279558
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 6.0015998439 4309450 15968718 17522070 3786805 16227642 19085960 2869522 19336974 9327722 11566570 21278145 16177239 7179309 6623471 10092053 7120509 15027814 7440962 10915739 3732212 6884620
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 6.0020420201
MESH:D056486 Drug-Induced Liver Injury Tetracycline 6.0017522070
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.6311462148
MESH:D004381 Duodenal Ulcer Capsaicin 4.5311535926 10671773
MESH:D050171 Dyslipidemias Dietary Fats 3.3318367378
MESH:D004487 Edema Arachidonic Acid 6.609831321 16716910 9599246 7990266 11698051 15177302
MESH:D004487 Edema Tetrachlorodibenzodioxin 6.6012711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.7316714409 18230668 15322242
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 8.3912538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 8.3919031437
MESH:D004714 Endometrial Hyperplasia Genistein 4.4216402032
MESH:D016889 Endometrial Neoplasms Genistein 7.1611473722
MESH:D016889 Endometrial Neoplasms Tamoxifen 7.1616202921 17893378 19155303 20544844
MESH:D004715 Endometriosis Mifepristone 8.6516134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 8.659294722 10568697
MESH:D004935 Esophageal Diseases Capsaicin 5.5319566590
MESH:D004938 Esophageal Neoplasms Fluorouracil 2.4116785472 17638652 16481741 16337965 15173087
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.8911564622
MESH:D005234 Fatty Liver Carbon Tetrachloride 28.6915959796 16045604 17595544 61145 16239168 19224547 12795759 12631006
MESH:D005234 Fatty Liver Cyclosporine 28.6919224547
MESH:D005234 Fatty Liver Dietary Fats 28.6917967931 19004024 18296743 19551842
MESH:D005234 Fatty Liver Ethinyl Estradiol 28.6915345470
MESH:D005234 Fatty Liver Tamoxifen 28.6919224547 14986274
MESH:D005234 Fatty Liver Tetracycline 28.6919224547 16917069
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.1316709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.2911858732
MESH:D005334 Fever Arachidonic Acid 4.5111852909
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.3514745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.0119069698
MESH:D005355 Fibrosis Carbon Tetrachloride 19.7318705752
MESH:D005355 Fibrosis Cyclosporine 19.7312639820 12168785
MESH:D005355 Fibrosis Dietary Fats 19.7318296743
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 19.7320067830
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.058708960
MESH:D005909 Glioblastoma Capsaicin 7.2518405923
MESH:D005909 Glioblastoma Genistein 7.2516598420
MESH:D005910 Glioma Fluorouracil 6.3216145905
MESH:D005910 Glioma tanshinone 6.3216955220
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.4210696789
MESH:D006258 Head and Neck Neoplasms Fluorouracil 3.2715162350 15102660 18337622
MESH:D006356 Heartburn Capsaicin 5.5319566590
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.2411294989 10048152
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.2515720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.1811000095
MESH:D006505 Hepatitis Carbon Tetrachloride 3.4319900420 19110552
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 2.7216120746 15340226 12621046
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.8715340226 18606429 8697196 16959395 16354765
MESH:D006930 Hyperalgesia Capsaicin 4.1917434803 17043245
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.3616899240
MESH:D006937 Hypercholesterolemia Dietary Fats 3.4421332399
MESH:D006949 Hyperlipidemias Dietary Fats 3.4521332399
MESH:D006973 Hypertension Cyclosporine 4.7310903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 4.7318670907 18850075
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.9215338365
MESH:D017379 Hypertrophy, Left Ventricular tanshinone 5.0919662366
MESH:D007021 Hypospadias Ethinyl Estradiol 3.6416569931 16945680
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.3012013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.3717937319
MESH:D007249 Inflammation Arachidonic Acid 14.959831321 15177302 17371808
MESH:D007249 Inflammation Capsaicin 14.9516956363
MESH:D007249 Inflammation Dietary Fats 14.9520412841
MESH:D007249 Inflammation Tamoxifen 14.9519457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 14.9512200463 12878042
MESH:D007333 Insulin Resistance bisphenol A 7.1216393666
MESH:D007333 Insulin Resistance Dietary Fats 7.1211836018 18457598
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.1816580747
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.2715604871
MESH:D007674 Kidney Diseases Cyclosporine 2.248314463 10903974 18776723
MESH:D007680 Kidney Neoplasms Cyclosporine 11.6112371664
MESH:D007680 Kidney Neoplasms Fluorouracil 11.6116985049
MESH:D007680 Kidney Neoplasms Tamoxifen 11.6118625569
MESH:D007938 Leukemia Genistein 2.9417468513 18980019
MESH:D008064 Lipidoses Tamoxifen 3.0315342952 17567588
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 6.3216239168 11903743 16221502 16943688 17334410 11408273 21278145 17157831 17174718
MESH:D008103 Liver Cirrhosis Dietary Fats 6.3218296743
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 4.7820821823 15730626 17766677 12546737 12741479 15818738 15052691 12898905 17976157 18156304 12586293 16015684 16011737 18205269 14724832 18376398 15996030 12632514 12958196 12445421 17565644 13678700 18317297 17805973 18263696 17761835 15650968 15673190 16116963 17714472 15893842 16027843 15959796 17640975 16192424 18429990 12632512 15338365 17631135 15876570 15362042 18412020 18339082 12445418 18187930 17525996 11481614 10355542 15123356 17708605 17481882 12667390 18166357 18279442 18277467 16248980 16638106 18418968 12389079 18251166 18705752 18395914 16097048 17557913 17900296 18054572 16136751 17721639 18472094 18210741 18472332 18395095 17823541 14512876 15370692 17869086 14620537 12609069 12649538 14716833 18006644 18420326 15931870 12666154 14748882 17944888 15925388 14716496 15057751 18481824 17698563 16033810 17922224
MESH:D008106 Liver Cirrhosis, Experimental Genistein 4.7817823541
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 4.7818564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 4.7812878042
MESH:D008107 Liver Diseases Capsaicin 4.3516956363
MESH:D008107 Liver Diseases Carbon Tetrachloride 4.3516246199 15830285 15720792 17285989 16964402
MESH:D017093 Liver Failure Carbon Tetrachloride 3.9915123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 3.5414706259 16899240
MESH:D008113 Liver Neoplasms Aflatoxin B1 20.922125692 15890375 9163691 18177683
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 20.9219294768
MESH:D008113 Liver Neoplasms dicyclanil 20.9220118626
MESH:D008113 Liver Neoplasms Fluorouracil 20.9217045692 15113037 18383874 16603448
MESH:D008113 Liver Neoplasms Methapyrilene 20.9215890375
MESH:D008113 Liver Neoplasms Tamoxifen 20.9216684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 20.9216984957
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 9.198603461
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 9.1912014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 9.1912151625
MESH:D008175 Lung Neoplasms Aflatoxin B1 6.3714755239
MESH:D008175 Lung Neoplasms bexarotene 6.3717849452
MESH:D008175 Lung Neoplasms Fluorouracil 6.3715246190
MESH:D008175 Lung Neoplasms Tamoxifen 6.3718625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 6.3711884234 19555203
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.6215086387
MESH:D016410 Lymphoma, T-Cell, Cutaneous bexarotene 4.9811161223
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.5919428831
MESH:D008325 Mammary Neoplasms, Experimental bexarotene 9.4619196722 15591091 19196723
MESH:D008325 Mammary Neoplasms, Experimental Genistein 9.4612929590 14578162
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 9.4611731420 19196723 14580682 16827153 19196722
MESH:D020149 Manganese Poisoning Tamoxifen 4.3819453300
MESH:D008545 Melanoma Tamoxifen 1.8612393984 19393235
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.0115990972
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.6216801185
MESH:D009062 Mouth Neoplasms Fluorouracil 3.5016757204 18986760
MESH:D009101 Multiple Myeloma Capsaicin 4.0417505005
MESH:D009203 Myocardial Infarction Genistein 2.7917141266
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.8812213967
MESH:D015428 Myocardial Reperfusion Injury Genistein 3.5317141266
MESH:D009362 Neoplasm Metastasis Tamoxifen 2.4819393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.4619410462
MESH:D009369 Neoplasms Fluorouracil 2.5318239605 18600527 16928823
MESH:D009376 Neoplasms, Hormone-Dependent bexarotene 10.3619196722
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 10.3619189210 19196722 19200415
MESH:D009395 Nephritis, Interstitial Tetracycline 4.619884423
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.2717954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.1419348381 18481113
MESH:D009421 Nervous System Malformations bisphenol A 15.4411399458 16427766
MESH:D009421 Nervous System Malformations Genistein 15.4416427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 15.4414600291
MESH:D020078 Neurogenic Inflammation Capsaicin 4.9317961222
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.3216436463
MESH:D009765 Obesity Capsaicin 4.8719056576
MESH:D009765 Obesity Dietary Fats 4.8718674790 21332399 19632207 20132043 20518802 18457598 16723640 17217161 11836018
MESH:D010024 Osteoporosis Genistein 3.1519401787
MESH:D015663 Osteoporosis, Postmenopausal Genistein 3.9216169203
MESH:D010049 Ovarian Diseases bisphenol A 4.8211985600
MESH:D010051 Ovarian Neoplasms Genistein 5.0519005980
MESH:D010051 Ovarian Neoplasms Mifepristone 5.0516525653
MESH:D010146 Pain Capsaicin 3.8816996476 19081190 17434803 17043245 17084039 18987195
MESH:D010190 Pancreatic Neoplasms Fluorouracil 2.6116929163 16500647 19003803 15113037
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.5311578682
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.0812520081
MESH:D010391 Pemphigoid, Bullous Tetracycline 5.2611026799
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.3918163543
MESH:D011230 Precancerous Conditions Cyclosporine 3.0812371664
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 8.9310548101
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 8.9311399792 11118676 11222880 11896295
MESH:D017096 Prion Diseases Tetracycline 5.2410903871
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 4.0520887781
MESH:D011471 Prostatic Neoplasms bisphenol A 2.1316740699
MESH:D011471 Prostatic Neoplasms Fluorouracil 2.1319082440 18626508
MESH:D011471 Prostatic Neoplasms Genistein 2.1316925846 15256057 15378649
MESH:D011471 Prostatic Neoplasms Tamoxifen 2.1315067354
MESH:D011537 Pruritus Ethinyl Estradiol 3.1415861022 16919318
MESH:D011565 Psoriasis Cyclosporine 2.1716882103
MESH:D011629 Puberty, Precocious bisphenol A 4.6110548101
MESH:D012004 Rectal Neoplasms Fluorouracil 3.8615538739 18722050 18286688 16160472
MESH:D015427 Reperfusion Injury Capsaicin 3.8818460982 19211983
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.6718990726
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 1.9716192470
MESH:D013088 Spermatocele Ethinyl Estradiol 10.9816709447
MESH:D013088 Spermatocele Tamoxifen 10.9816709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.8719457130
MESH:D013274 Stomach Neoplasms Fluorouracil 2.0017522103 18396642 16424979 18567086 15786421 17498489 16951190 19084572 17172411 19015929
MESH:D019966 Substance-Related Disorders bisphenol A 3.8116684133 16045194
MESH:D013705 Temporomandibular Joint Disorders Capsaicin 5.5517997062
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.4611994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.0115669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.7312697716
MESH:D014062 Tongue Neoplasms Fluorouracil 3.8416280240
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 2.2916712894 17572228 8653321
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 3.7316803524
MESH:D014591 Uterine Diseases bisphenol A 4.8414652134
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.1314692618
MESH:D014605 Uveitis Cyclosporine 3.811336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.4212125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.3814671159 15869587
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.0815886252
MESH:D015430 Weight Gain Dietary Fats 3.5916723640
MESH:D014985 Xerophthalmia Cyclosporine 4.2717120751
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA51
    • No data
    Releated disease ID Related disease Name
    PA446858Neurodegenerative Diseases
    PA165110266Posterior Cortical Atrophy
    PA445451Psoriasis
    PA443319Alzheimer Disease
    PA447230HIV
    PA446213HIV Infections
    PA444528Hyperlipidemias
    PA444682Kidney Diseases
    PA162370415metabolic syndrome
    PA443319Alzheimer Disease
    PA165108110Dyslipidaemia
    Releated drug ID Related drug Name
    PA448500atorvastatin
    PA133950441hmg coa reductase inhibitors
    PA451089pravastatin
    PA451363simvastatin
    PA448039acitretin
    PA451260ritonavir
    PA164712505Antivirals for treatment of HIV infections, combinations
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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