AutismKB 2.0

Annotation Detail for ZKSCAN2


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Basic Information Top
Gene Symbol:ZKSCAN2 ( FLJ23199,ZNF694,ZSCAN31 )
Gene Full Name: zinc finger with KRAB and SCAN domains 2
Band: 16p12.1
Quick LinksEntrez ID:342357; OMIM: NA; Uniprot ID:ZKSC2_HUMAN; ENSEMBL ID: ENSG00000155592; HGNC ID: 25677
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C006780 bisphenol A bisphenol A results in increased expression of ZKSCAN2 mRNAincreases expression 19371625
D015025 Zearalenone Zearalenone results in increased expression of ZKSCAN2 mRNAincreases expression 19371625
D019833 Genistein Genistein results in increased expression of ZKSCAN2 mRNAincreases expression 19371625
C016340 o,p'-DDT o,p'-DDT results in increased expression of ZKSCAN2 mRNAincreases expression 19371625
C059514 resveratrol resveratrol results in increased expression of ZKSCAN2 mRNAincreases expression 19371625
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D058186 Acute Kidney Injury resveratrol 4.2216538975
MESH:D000230 Adenocarcinoma Genistein 2.5411473722
MESH:D000236 Adenoma resveratrol 3.5015688382
MESH:D000544 Alzheimer Disease resveratrol 2.6316162502 16183991
MESH:D001169 Arthritis, Experimental resveratrol 3.7017115116
MESH:D050197 Atherosclerosis resveratrol 3.4616873680 17967414
MESH:D001862 Bone Resorption bisphenol A 4.2411985600
MESH:D002545 Brain Ischemia resveratrol 4.8217600658
MESH:D001943 Breast Neoplasms bisphenol A 2.0317123778
MESH:D001943 Breast Neoplasms Genistein 2.0316541309 17200150 16873071
MESH:D001943 Breast Neoplasms resveratrol 2.0316393696 17534123 17651959
MESH:D006528 Carcinoma, Hepatocellular Genistein 3.4316924424
MESH:D006528 Carcinoma, Hepatocellular resveratrol 3.4316227395 19321006
MESH:D002278 Carcinoma in Situ bisphenol A 5.5317123778
MESH:D018827 Carcinoma, Lewis Lung resveratrol 5.1316675471
MESH:D002294 Carcinoma, Squamous Cell resveratrol 2.7916227395
MESH:D002318 Cardiovascular Diseases Genistein 8.3116332659
MESH:D002318 Cardiovascular Diseases resveratrol 8.3115458977
MESH:D003092 Colitis resveratrol 4.6116474422
MESH:D003110 Colonic Neoplasms Genistein 4.1117182828
MESH:D003110 Colonic Neoplasms resveratrol 4.1116338953
MESH:D015179 Colorectal Neoplasms resveratrol 2.2316550006
MESH:D003327 Coronary Disease resveratrol 3.9616507316
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 4.0716873680
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 2.5516647724
MESH:D003928 Diabetic Nephropathies resveratrol 4.2916286809
MESH:D004487 Edema resveratrol 3.738985016
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 4.4617872969
MESH:D004714 Endometrial Hyperplasia Genistein 5.1316402032
MESH:D016889 Endometrial Neoplasms Genistein 3.5811473722
MESH:D020345 Enterocolitis, Necrotizing resveratrol 5.3317923197
MESH:D005909 Glioblastoma Genistein 3.4716598420
MESH:D006561 Herpes Simplex resveratrol 4.7216876885
MESH:D006937 Hypercholesterolemia resveratrol 4.3817188708
MESH:D006949 Hyperlipidemias resveratrol 4.4316873680
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 4.6517488730
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 5.1317600658
MESH:D007249 Inflammation resveratrol 3.0016366677
MESH:D007251 Influenza, Human resveratrol 5.1616624496
MESH:D007333 Insulin Resistance bisphenol A 3.5016393666
MESH:D007938 Leukemia Genistein 3.1717468513 18980019
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 3.7916087638
MESH:D008106 Liver Cirrhosis, Experimental Genistein 2.0617823541
MESH:D008113 Liver Neoplasms resveratrol 2.8119073162 19321006 19812893 20405173
MESH:D016393 Lymphoma, B-Cell resveratrol 4.7017088997
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 4.1714749477
MESH:D015674 Mammary Neoplasms, Animal resveratrol 4.7815688416
MESH:D008325 Mammary Neoplasms, Experimental Genistein 7.0014578162 12929590
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 7.008985016 11606380
MESH:D008545 Melanoma resveratrol 2.4017992120
MESH:D008659 Metabolic Diseases resveratrol 4.7517112576
MESH:D009101 Multiple Myeloma resveratrol 3.7116267019 14749477 17049120 17935668 16490592 17164350
MESH:D009134 Muscular Atrophy, Spinal resveratrol 5.4117962980
MESH:D009203 Myocardial Infarction Genistein 6.4117141266
MESH:D009203 Myocardial Infarction resveratrol 6.4116317513 16456233 16525036 17188708 17125593 17015251
MESH:D017202 Myocardial Ischemia resveratrol 4.3017015251 17125593
MESH:D015428 Myocardial Reperfusion Injury Genistein 3.9317141266
MESH:D009205 Myocarditis resveratrol 5.3017322642
MESH:D009374 Neoplasms, Experimental resveratrol 4.488985016
MESH:D009421 Nervous System Malformations bisphenol A 11.3916427766 11399458
MESH:D009421 Nervous System Malformations Genistein 11.3916427766
MESH:D019636 Neurodegenerative Diseases resveratrol 4.1117652729
MESH:D020078 Neurogenic Inflammation resveratrol 4.8017929310
MESH:D010024 Osteoporosis Genistein 3.4519401787
MESH:D015663 Osteoporosis, Postmenopausal Genistein 11.5316169203
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 11.5317513867
MESH:D010049 Ovarian Diseases bisphenol A 5.5311985600
MESH:D010051 Ovarian Neoplasms Genistein 2.6819005980
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 11.7410548101
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 11.7416679765
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 4.5820887781
MESH:D011471 Prostatic Neoplasms bisphenol A 2.6216740699
MESH:D011471 Prostatic Neoplasms Genistein 2.6216925846 15256057 15378649
MESH:D011471 Prostatic Neoplasms resveratrol 2.6215767336 17804756 17675339 17636462 17718901 16731767
MESH:D011629 Puberty, Precocious bisphenol A 5.3310548101
MESH:D051436 Renal Insufficiency, Chronic resveratrol 6.1916325855
MESH:D015427 Reperfusion Injury resveratrol 3.4215827377 17058453 16314181 17520802 16317513
MESH:D012878 Skin Neoplasms resveratrol 3.178985016 15837718
OMIM:601367 STROKE, ISCHEMIC resveratrol 4.8316321402
MESH:D019966 Substance-Related Disorders bisphenol A 4.5216045194 16684133
MESH:D014062 Tongue Neoplasms resveratrol 4.5616227395
MESH:D002583 Uterine Cervical Neoplasms resveratrol 4.4517473185
MESH:D014591 Uterine Diseases bisphenol A 5.6214652134
MESH:D014594 Uterine Neoplasms resveratrol 4.5717044934
MESH:D018487 Ventricular Dysfunction, Left resveratrol 4.7817488730
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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