AutismKB 2.0

Annotation Detail for IGFALS


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:IGFALS ( ALS )
Gene Full Name: insulin-like growth factor binding protein, acid labile subunit
Band: 16p13.3
Quick LinksEntrez ID:3483; OMIM: 601489; Uniprot ID:ALS_HUMAN; ENSEMBL ID: ENSG00000099769; HGNC ID: 5468
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
No data
Pathway IDPathway Name
Diabetes pathways
No data
No data
Pathway IDPathway Name
500133Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Protei
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1944Breast cancer
2021Acromegaly
2134Amyotrophic lateral sclerosis
No data
No data
Desease Name
Acid-labile subunit, deficiency of
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of IGFALS mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of IGFALS mRNAaffects expression 17562736
D000638 Amiodarone Amiodarone results in increased expression of IGFALS mRNAincreases expression 19774075
D000638 Amiodarone Amiodarone affects the expression of IGFALS mRNAaffects expression 19483382
D000643 Ammonium Chloride Ammonium Chloride affects the expression of IGFALS mRNAaffects expression 16483693
D001553 Benzbromarone Benzbromarone affects the expression of IGFALS mRNAaffects expression 19483382
D002251 Carbon Tetrachloride Carbon Tetrachloride results in decreased expression of IGFALS mRNAdecreases expression 16239168
D002713 Chlorine [Ozone co-treated with Chlorine] results in increased expression of IGFALS mRNAaffects cotreatment|increases expression 18636392
D002994 Clofibrate Clofibrate affects the expression of IGFALS mRNAaffects expression 19483382
D002995 Clofibric Acid Clofibric Acid affects the expression of IGFALS mRNAaffects expression 17602206
C030123 coumarin coumarin results in decreased expression of IGFALS mRNAdecreases expression 18480146
C007262 deoxynivalenol deoxynivalenol inhibits the reaction [Glutathione results in increased expression of IGFALS mRNA]decreases reaction|increases expression 19805407
C007262 deoxynivalenol deoxynivalenol results in decreased expression of IGFALS mRNAdecreases expression 19805407
C007262 deoxynivalenol deoxynivalenol results in decreased expression of IGFALS proteindecreases expression 19805407
19625342
D004052 Diethylnitrosamine Diethylnitrosamine results in decreased expression of IGFALS mRNAdecreases expression 19638242
C015854 estradiol valerate estradiol valerate results in decreased expression of IGFALS proteindecreases expression 10843175
D004966 Estrogens, Conjugated (USP) Estrogens, Conjugated (USP) results in decreased expression of IGFALS proteindecreases expression 10843175
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of IGFALS proteindecreases expression 10843175
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of IGFALS proteinincreases expression 15817916
D005001 Ethionine Ethionine affects the expression of IGFALS mRNAaffects expression 19483382
C056933 fumonisin B1 fumonisin B1 results in decreased expression of IGFALS mRNAdecreases expression 16221962
D005978 Glutathione deoxynivalenol inhibits the reaction [Glutathione results in increased expression of IGFALS mRNA]decreases reaction|increases expression 19805407
D005978 Glutathione Glutathione results in increased expression of IGFALS mRNAincreases expression 19805407
D008701 Methapyrilene Methapyrilene results in decreased expression of IGFALS mRNAdecreases expression 16393664
D009853 Omeprazole Omeprazole affects the expression of IGFALS mRNAaffects expression 19483382
D010126 Ozone [Ozone co-treated with Chlorine] results in increased expression of IGFALS mRNAaffects cotreatment|increases expression 18636392
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of IGFALS mRNAaffects binding|increases activity|increases expression 19710929
C006253 pirinixic acid pirinixic acid results in decreased expression of IGFALS mRNAdecreases expression 16221962
18445702
20059764
C006253 pirinixic acid PPARA protein affects the reaction [pirinixic acid results in decreased expression of IGFALS mRNA]affects reaction|decreases expression 16221962
C006253 pirinixic acid PPARA protein promotes the reaction [pirinixic acid results in decreased expression of IGFALS mRNA]decreases expression|increases reaction 20059764
C006253 pirinixic acid pirinixic acid affects the expression of IGFALS mRNAaffects expression 19483382
D011441 Propylthiouracil Propylthiouracil affects the expression of IGFALS mRNAaffects expression 19483382
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of IGFALS mRNAdecreases expression 16054898
D013853 Thioacetamide Thioacetamide affects the expression of IGFALS mRNAaffects expression 19483382
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.6615322242 11752688 14514962
MESH:D000138 Acidosis Ammonium Chloride 3.3718287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.7517505938
MESH:D055371 Acute Lung Injury Chlorine 8.5520601635
MESH:D055371 Acute Lung Injury pirinixic acid 8.5518653653
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.7714692618
MESH:D000236 Adenoma Diethylnitrosamine 2.746695378 10737359
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 16.1617162532 17620307 16434500 19052882 18056438 19061943
MESH:D018248 Adenoma, Liver Cell pirinixic acid 16.1616434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 16.1616835633
MESH:D000544 Alzheimer Disease Ozone 2.4015513908
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.7811748828
MESH:D000799 Angioedema Acetaminophen 3.6510982225
MESH:D001145 Arrhythmias, Cardiac Amiodarone 3.6420041841 18057881 18218290
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.2811256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.5515885639
MESH:D001172 Arthritis, Rheumatoid Ozone 2.5115570426
MESH:D001249 Asthma Ozone 2.5817854713 16373670
MESH:D001281 Atrial Fibrillation Amiodarone 3.7619698954 18651412
MESH:D001321 Autistic Disorder Acetaminophen 2.2218445737
MESH:D001321 Autistic Disorder Glutathione 2.2218929414 16917939 19056591 19267885
MESH:D001778 Blood Coagulation Disorders Amiodarone 54.9819483382
MESH:D001778 Blood Coagulation Disorders Benzbromarone 54.9819483382
MESH:D001778 Blood Coagulation Disorders Clofibrate 54.9819483382
MESH:D001778 Blood Coagulation Disorders Ethionine 54.9819483382
MESH:D001778 Blood Coagulation Disorders Omeprazole 54.9819483382
MESH:D001778 Blood Coagulation Disorders pirinixic acid 54.9819483382
MESH:D001778 Blood Coagulation Disorders Propylthiouracil 54.9819483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 54.9812125929
MESH:D001778 Blood Coagulation Disorders Thioacetamide 54.9819483382
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.6015340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.6415746008
MESH:D001943 Breast Neoplasms Diethylnitrosamine 2.0017474063
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.0020435547
MESH:D016535 Bronchial Hyperreactivity Ozone 3.5315516495 14754758 18315731 17626835 19059883 18417511 16777450
MESH:D002100 Cachexia Ozone 4.5516183385
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.5916011737 16097048 10355542 16227642 16192424 15673190 16124888 15721981 18705752 15700767 16050911 3786805
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.6516835633
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 10.9816705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 10.983084413
MESH:D006528 Carcinoma, Hepatocellular Benzbromarone 10.981701930
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 10.9818788625
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 10.9811831363 17173139 19383236 16288022 19335982 18788625 19107877 19701751 19519916 19919837 19822196 18506893 20432363 17761372 16681979 16328049 18971187 3084413 16830150 18393292 19418558 16502159 18494052 17978847 16540662 18210153 20101231 19539802 20007298 20514400 17162532 17138121 18691550 19171122 19394651 20727157 18056438 19052882 21159647 16878318 20084675 16569478 18665156 10672840 3581430 17055752 16807293 19208518 18785209 20214788 10737359 20935162 20512989 20524982 18978308 16935385 16779866 17428255 16698587
MESH:D006528 Carcinoma, Hepatocellular Thioacetamide 10.9817997003
MESH:D002294 Carcinoma, Squamous Cell Glutathione 3.3217015178
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.2618670907 18850075 16120746
MESH:D002311 Cardiomyopathy, Dilated Amiodarone 2.8315710769 19225199
MESH:D002341 Carotid Artery Thrombosis Amiodarone 4.8918974383
MESH:D002386 Cataract Acetaminophen 2.4710977129
MESH:D002471 Cell Transformation, Neoplastic Clofibrate 6.541399818
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 6.5421159647 17174075 2727394 7505956
MESH:D002637 Chest Pain Omeprazole 4.9115447763
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 15.1919052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 15.1916835633
MESH:D018281 Cholangiocarcinoma Thioacetamide 15.1918291259
MESH:D002779 Cholestasis Ethinyl Estradiol 7.2817681005 15861022 16919318 11677210 17333356 17110522 16105132
MESH:D002779 Cholestasis pirinixic acid 7.2819176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.0315668235 15340226 12621046 8697196 16354765
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.9014669216 17141729
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 1.2510048152 20055451 15322242
MESH:D003490 Cyanosis 2,4-dinitrotoluene 3.8318551238
MESH:D003550 Cystic Fibrosis Glutathione 4.3219747007
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3418249437
MESH:D003924 Diabetes Mellitus, Type 2 coumarin 6.9219647726
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 6.9220387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 6.9217107852
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 21.2518551238 21346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 21.2519420014 19085960 2444490 15968718 19923254 14986274 15619225 11287661 17562736 16109766 12540782 17522070 16393943 18071297 10774834 12958197 12392966 12705907 11739529 16781746 19164858 11421492 11743745 19739265 14550746 19416960 16485898 12153990 12594235 11834606 19370779 16177239 11529661 14725611 10663392 16081117 18713872 11461765 17906064 10915739 16227642
MESH:D056486 Drug-Induced Liver Injury Amiodarone 21.2518218290 15265979
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 21.2517522070 15027814 16227642 3786805 21278145 10092053 9327722 6884620 2869522 19336974 15968718 3732212 4309450 7120509 15998439 7179309 19085960 6623471 7440962 11566570 16177239 10915739
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 21.2519107877
MESH:D056486 Drug-Induced Liver Injury fumonisin B1 21.2516221962
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 21.2520420201
MESH:D056486 Drug-Induced Liver Injury Thioacetamide 21.2512963478
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.9119426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.6211462148
MESH:D004381 Duodenal Ulcer Omeprazole 4.1515991576 16613094 17151854 21218061
MESH:D050171 Dyslipidemias Clofibrate 3.9316707586
MESH:D004417 Dyspnea Chlorine 4.4320016425
MESH:D004487 Edema pirinixic acid 5.9712083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 5.9711000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.7116714409 15322242 18230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.0112538720
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.869294722 10568697
MESH:D007172 Erectile Dysfunction estradiol valerate 5.6314972507
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.9216302075
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.8711564622
MESH:D005218 Fat Necrosis Thioacetamide 5.5316456712
MESH:D005234 Fatty Liver Amiodarone 28.4714986274
MESH:D005234 Fatty Liver Carbon Tetrachloride 28.4716239168 12795759 17595544 12631006 61145 15959796 19224547 16045604
MESH:D005234 Fatty Liver Clofibrate 28.4719224547
MESH:D005234 Fatty Liver Diethylnitrosamine 28.4720387270 21071580
MESH:D005234 Fatty Liver Ethinyl Estradiol 28.4715345470
MESH:D005234 Fatty Liver pirinixic acid 28.4720131406 19236843
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.2711858732
MESH:D005355 Fibrosis Carbon Tetrachloride 7.9718705752
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 7.9720067830
MESH:D005739 Gas Poisoning Chlorine 4.8220016425
MESH:D005756 Gastritis Acetaminophen 3.4816983495
MESH:D005922 Glomerulonephritis, IGA deoxynivalenol 4.8616524712 15173396
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.4010696789
MESH:D006130 Growth Disorders marker/mechanism
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.2310048152 11294989
MESH:D006333 Heart Failure pirinixic acid 2.4220558911
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.1611000095
MESH:D006501 Hepatic Encephalopathy Thioacetamide 4.4018665440 15929193 17276928
MESH:D006505 Hepatitis Carbon Tetrachloride 8.8719900420 19110552
MESH:D006505 Hepatitis Thioacetamide 8.8716456712
MESH:D006529 Hepatomegaly Amiodarone 19.1615265979
MESH:D006529 Hepatomegaly fumonisin B1 19.1616221962
MESH:D006529 Hepatomegaly pirinixic acid 19.1616221962 19772884 19176532 18467677
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 19.1612621046 16120746 15340226
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.8516354765 15340226 18606429 8697196 16959395
MESH:D006930 Hyperalgesia Acetaminophen 2.5516870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.3416899240
MESH:D006937 Hypercholesterolemia Amiodarone 3.708137927 9751232
MESH:D006943 Hyperglycemia pirinixic acid 3.0220558911
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 1.8418670907 18850075
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.9015338365
MESH:D007021 Hypospadias Ethinyl Estradiol 3.6216569931 16945680
MESH:D007037 Hypothyroidism Amiodarone 10.9817991464 18020914
MESH:D007037 Hypothyroidism Propylthiouracil 10.9818031379 8137927
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.2812013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.3617937319
MESH:D007249 Inflammation Diethylnitrosamine 4.5718785209
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 4.5712200463 12878042
MESH:D007333 Insulin Resistance pirinixic acid 2.5116306350
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.1616580747
MESH:D007674 Kidney Diseases Acetaminophen 2.0912587719 15629191
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 2.8216705839
MESH:D016773 Leishmaniasis, Cutaneous Omeprazole 3.9419248655
MESH:D008064 Lipidoses Amiodarone 3.3715342952 17567588
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 6.2616943688 17174718 11408273 17334410 21278145 17157831 16239168 11903743 16221502
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 6.2618522880 18407596 18665156 19638242 20032147
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 4.7518277467 14716496 18395914 12632512 17698563 18205269 18472094 16116963 15931870 17766677 16248980 11481614 18210741 12667390 16015684 18156304 17922224 18418968 16638106 14716833 14512876 17565644 18054572 15123356 12898905 18339082 17805973 14724832 17557913 12741479 15338365 12445421 18412020 18395095 18006644 16011737 17714472 12586293 14748882 15996030 12666154 16097048 16136751 16192424 17823541 15362042 15925388 10355542 17869086 20821823 18376398 16027843 18472332 15650968 15818738 18166357 15370692 17721639 14620537 15052691 17481882 18705752 12445418 12958196 12546737 12609069 12649538 17640975 12389079 15057751 18251166 18481824 15673190 15876570 17708605 15893842 12632514 18263696 17761835 18317297 15730626 16033810 17525996 13678700 17976157 18187930 17631135 18429990 17944888 17900296 18279442 15959796 18420326
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 4.7515474484
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 4.7512878042
MESH:D008106 Liver Cirrhosis, Experimental Thioacetamide 4.7512891558 18458672 15465738 16126171 18416461 17629604 17050028 15078482 18615449 18295389 17127702 15316131 15288473 15288472 11172339 15474484 16489207 11682029 15334695 16343077 15075984 15158331 18395095 17355460 18263696 18032466 12175628 15095483 16511523 16248980 12679928 18380797 12085344 18031379 14739098 17292413 16098781 15716488 12531686 12557150 18606216 11481614 10677585 16097051 15362042
MESH:D008107 Liver Diseases Acetaminophen 8.9716610002 19784758 16611625 12969438 11587558 19460945 12587719 19014921
MESH:D008107 Liver Diseases Carbon Tetrachloride 8.9716964402 15720792 15830285 17285989 16246199
MESH:D008107 Liver Diseases Diethylnitrosamine 8.9717034775
MESH:D008107 Liver Diseases Thioacetamide 8.9715158337 16337175 18374380
MESH:D017093 Liver Failure Carbon Tetrachloride 3.9715123358
MESH:D017114 Liver Failure, Acute Acetaminophen 15.2816871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 15.2816899240 14706259
MESH:D017114 Liver Failure, Acute Thioacetamide 15.2815633222 15313186 17276928 12479984
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 17.0419294768
MESH:D008113 Liver Neoplasms Clofibric Acid 17.0417602206
MESH:D008113 Liver Neoplasms Diethylnitrosamine 17.0420137499 19551842 19294768 2422723 19638242 16942905 20452335 20434301 19499222 15885732 19426721 19427195 21278145 19255062 18754104 20405173 12112319 20118626 19812893 19996281 19690152 10737359 18644402 21167192 12771043 19833225 15175105 2862719 20101389 20583210 18977376 19090486 19254457 21047994 18648771 19850985 21071580 9163691 19642983 19073162 19256749 18978307 20492335 20501860
MESH:D008113 Liver Neoplasms Methapyrilene 17.0415890375
MESH:D008113 Liver Neoplasms pirinixic acid 17.0420007298 16377806 15890375
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 17.0416984957
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 9.1112014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 9.1117854601 18079962 19519916 16267830 16842330 19009564 9362446 18775883 18253720 18544905 18164116 19539802 19126423 17942915 18093689 21159647 18308698 19004024 17174075 3124819 2563599 18282651
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 9.1112151625
MESH:D008133 Long QT Syndrome Amiodarone 3.4417391786 15350150 11989578
MESH:D008171 Lung Diseases Amiodarone 7.1712587719
MESH:D008171 Lung Diseases Ozone 7.178266340 19066396
MESH:D017563 Lung Diseases, Interstitial Amiodarone 4.2918516814
MESH:D055370 Lung Injury Ozone 3.6620417186
MESH:D008175 Lung Neoplasms Diethylnitrosamine 3.2920970405 20512841 21163286 6695378
MESH:D008175 Lung Neoplasms Ozone 3.297614698 8597069
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 3.2919555203 11884234
MESH:D008546 Melanoma, Experimental Acetaminophen 3.3819513568
MESH:D008679 Metaplasia Ozone 4.9110496685
MESH:D009135 Muscular Diseases pirinixic acid 3.3216239165
MESH:D009181 Mycoses Amiodarone 4.7117974566 12754197
MESH:D009203 Myocardial Infarction pirinixic acid 2.0719151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.8712213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.8016411023
MESH:D009336 Necrosis 2,4-dinitrotoluene 3.6718551238
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 2.499029167 3581430
MESH:D009369 Neoplasms pirinixic acid 1.8617405874
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.0314600291
MESH:D019636 Neurodegenerative Diseases Acetaminophen 7.6618514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 7.6620387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.9220387270
MESH:D052556 Niemann-Pick Disease, Type C Clofibrate 4.759802331
MESH:D009765 Obesity pirinixic acid 1.7720558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 3.2612819281 16049721
MESH:D010146 Pain Acetaminophen 2.2416870215
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 2.3616540662
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.5111578682
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.0612520081
MESH:D010538 Peritonitis Ozone 3.9416369182
MESH:D011014 Pneumonia Ozone 4.2018007984 18929643 18381685
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.3718163543
MESH:D011230 Precancerous Conditions Diethylnitrosamine 3.392563599
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.0011118676 11896295 11222880 11399792
MESH:D011537 Pruritus Ethinyl Estradiol 3.1216919318 15861022
MESH:D011658 Pulmonary Fibrosis Amiodarone 2.7812832656 12490602 11597910
MESH:D015427 Reperfusion Injury pirinixic acid 2.2919058328
MESH:D012120 Respiration Disorders Chlorine 5.0218579056
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.6518990726
MESH:D012640 Seizures 2,4-dinitrotoluene 2.4118551238
OMIM:609620 SHORT QT SYNDROME 1 Amiodarone 4.8918724381
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 1.9616192470
MESH:D013088 Spermatocele Ethinyl Estradiol 3.7516709447
MESH:D013272 Stomach Diseases Omeprazole 4.4218545984
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 1.7518456281
MESH:D013276 Stomach Ulcer Amiodarone 7.0118087811
MESH:D013276 Stomach Ulcer Omeprazole 7.0118237397 15991576 10750652 16755016 11906479 17977527
MESH:D013610 Tachycardia Amiodarone 4.1111238279
MESH:D017180 Tachycardia, Ventricular Amiodarone 4.0119225199
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.4411994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.9915669648
MESH:D013959 Thyroid Diseases Amiodarone 11.4119731979
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 11.4112697716
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 6.937505956
MESH:D013964 Thyroid Neoplasms Propylthiouracil 6.9315710170
MESH:D013971 Thyrotoxicosis Amiodarone 4.6718020914 19584973
MESH:D016171 Torsades de Pointes Amiodarone 4.0011989578 17467628
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 2.2216049721
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 4.1210091137
MESH:D014581 Urticaria Acetaminophen 2.8010982225
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.1214692618
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.4012125929
MESH:D014689 Venous Insufficiency coumarin 5.5812708602
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.3715869587 14671159
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.0615886252
Pathway ID Pathway Name
REACT:15380 Diabetes pathways
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved