AutismKB 2.0

Annotation Detail for GPR142


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Basic Information Top
Gene Symbol:GPR142 ( PGR2 )
Gene Full Name: G protein-coupled receptor 142
Band: 17q25.1
Quick LinksEntrez ID:350383; OMIM: 609046; Uniprot ID:GP142_HUMAN; ENSEMBL ID: ENSG00000196169; HGNC ID: 20088
Relate to Another Database: SFARIGene; denovo-db
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Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C006780 bisphenol A bisphenol A results in increased expression of GPR142 mRNAincreases expression 19371625
D015025 Zearalenone Zearalenone results in increased expression of GPR142 mRNAincreases expression 19371625
C016340 o,p'-DDT o,p'-DDT results in increased expression of GPR142 mRNAincreases expression 19371625
C059514 resveratrol resveratrol results in increased expression of GPR142 mRNAincreases expression 19371625
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D058186 Acute Kidney Injury resveratrol 4.2716538975
MESH:D000236 Adenoma resveratrol 3.5215688382
MESH:D000544 Alzheimer Disease resveratrol 2.6316162502 16183991
MESH:D001169 Arthritis, Experimental resveratrol 3.7217115116
MESH:D050197 Atherosclerosis resveratrol 3.4816873680 17967414
MESH:D001862 Bone Resorption bisphenol A 4.2911985600
MESH:D002545 Brain Ischemia resveratrol 4.9117600658
MESH:D001943 Breast Neoplasms bisphenol A 2.3817123778
MESH:D001943 Breast Neoplasms resveratrol 2.3817534123 17651959 16393696
MESH:D006528 Carcinoma, Hepatocellular resveratrol 2.3416227395 19321006
MESH:D002278 Carcinoma in Situ bisphenol A 5.6217123778
MESH:D018827 Carcinoma, Lewis Lung resveratrol 5.2216675471
MESH:D002294 Carcinoma, Squamous Cell resveratrol 2.8016227395
MESH:D002318 Cardiovascular Diseases resveratrol 3.7315458977
MESH:D003092 Colitis resveratrol 4.6916474422
MESH:D003110 Colonic Neoplasms resveratrol 2.5016338953
MESH:D015179 Colorectal Neoplasms resveratrol 2.2316550006
MESH:D003327 Coronary Disease resveratrol 3.9816507316
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 4.1116873680
MESH:D003928 Diabetic Nephropathies resveratrol 4.3316286809
MESH:D004487 Edema resveratrol 3.788985016
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 4.5317872969
MESH:D020345 Enterocolitis, Necrotizing resveratrol 5.4117923197
MESH:D006561 Herpes Simplex resveratrol 4.8116876885
MESH:D006937 Hypercholesterolemia resveratrol 4.4317188708
MESH:D006949 Hyperlipidemias resveratrol 4.4916873680
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 4.7017488730
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 5.2117600658
MESH:D007249 Inflammation resveratrol 3.0216366677
MESH:D007251 Influenza, Human resveratrol 5.2716624496
MESH:D007333 Insulin Resistance bisphenol A 3.5316393666
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 3.8216087638
MESH:D008113 Liver Neoplasms resveratrol 2.8220405173 19812893 19073162 19321006
MESH:D016393 Lymphoma, B-Cell resveratrol 4.7617088997
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 4.2114749477
MESH:D015674 Mammary Neoplasms, Animal resveratrol 4.8815688416
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 3.348985016 11606380
MESH:D008545 Melanoma resveratrol 2.4117992120
MESH:D008659 Metabolic Diseases resveratrol 4.8017112576
MESH:D009101 Multiple Myeloma resveratrol 3.7416267019 16490592 14749477 17049120 17164350 17935668
MESH:D009134 Muscular Atrophy, Spinal resveratrol 5.5017962980
MESH:D009203 Myocardial Infarction resveratrol 3.1616525036 17015251 17188708 16456233 17125593 16317513
MESH:D017202 Myocardial Ischemia resveratrol 4.3317015251 17125593
MESH:D009205 Myocarditis resveratrol 5.3917322642
MESH:D009374 Neoplasms, Experimental resveratrol 4.568985016
MESH:D009421 Nervous System Malformations bisphenol A 4.4811399458 16427766
MESH:D019636 Neurodegenerative Diseases resveratrol 4.1517652729
MESH:D020078 Neurogenic Inflammation resveratrol 4.8617929310
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 4.7217513867
MESH:D010049 Ovarian Diseases bisphenol A 5.6211985600
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 12.0710548101
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 12.0716679765
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 4.6320887781
MESH:D011471 Prostatic Neoplasms bisphenol A 3.3916740699
MESH:D011471 Prostatic Neoplasms resveratrol 3.3917636462 17718901 17675339 16731767 17804756 15767336
MESH:D011629 Puberty, Precocious bisphenol A 5.4210548101
MESH:D051436 Renal Insufficiency, Chronic resveratrol 6.3116325855
MESH:D015427 Reperfusion Injury resveratrol 3.4316314181 15827377 16317513 17520802 17058453
MESH:D012878 Skin Neoplasms resveratrol 3.1915837718 8985016
OMIM:601367 STROKE, ISCHEMIC resveratrol 4.8816321402
MESH:D019966 Substance-Related Disorders bisphenol A 4.6116684133 16045194
MESH:D014062 Tongue Neoplasms resveratrol 4.6116227395
MESH:D002583 Uterine Cervical Neoplasms resveratrol 4.5017473185
MESH:D014591 Uterine Diseases bisphenol A 5.7314652134
MESH:D014594 Uterine Neoplasms resveratrol 4.6417044934
MESH:D018487 Ventricular Dysfunction, Left resveratrol 4.8617488730
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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