AutismKB 2.0

Annotation Detail for APP


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Basic Information Top
Gene Symbol:APP ( AAA,ABETA,ABPP,AD1,APPI,CTFgamma,CVAP,PN2 )
Gene Full Name: amyloid beta (A4) precursor protein
Band: 21q21.3
Quick LinksEntrez ID:351; OMIM: 104760; Uniprot ID:A4_HUMAN; ENSEMBL ID: ENSG00000142192; HGNC ID: 620
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa05010Alzheimer's disease
Pathway IDPathway Name
Signaling by GPCR
Hemostasis
Pathway IDPathway Name
200148Caspase cascade in apoptosis
200021Glypican 1 network
200103p75(NTR)-mediated signaling
Pathway IDPathway Name
P00003Alzheimer disease-amyloid secretase pathway
P00004Alzheimer disease-presenilin pathway
P00011Blood coagulation
No data
Related Diseases/Disorders Top
Desease IDDesease Name
Nervous system diseases
Neurodegenerative diseases
H00056Alzheimer's disease
Desease IDDesease Name
1740Alzheimer's disease
1828Encephalitis
1850Herpes
1856Obesity
1860Brain tumor
1871Hepatitis
1914Cerebrovascular disorder
1953Nervous system disease
1963Amyloidosis
1983Down syndrome
1986Eating disorder
1997Dental plaque
2035Brain disease
2051Leukemia
2062Neurodegenerative disorder
2118Adenovirus infection
2120Rabies
2134Amyotrophic lateral sclerosis
2198Psychotic disorder
2223Central nervous system disease
2244Prion disease
2259Hereditary disease
Desease Name
cognitive function
Alzheimer's disease
attention deficit disorder
dementia, frontotemporal
conduct disorder
PSYCH
Lewy Body Formation
NEUROLOGICAL
oppositional defiant disorder
cognitive trait
No data
Desease Name
Dementia, early-onset progressive, autosomal recessive
Cerebral amyloid angiopathy, Dutch, Italian, Iowa, Flemish, Arctic variants
Alzheimer disease 1, familial
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C095284 1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one 1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one inhibits the reaction [Ginkgo biloba extract 761 inhibits the reaction [APP protein results in decreased phosphorylation of CREB1 protein]]decreases phosphorylation|decreases reaction 18001288
C095284 1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one 1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one inhibits the reaction [ginkgolide C inhibits the reaction [APP protein results in decreased phosphorylation of CREB1 protein]]decreases phosphorylation|decreases reaction 18001288
C095284 1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one 1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one inhibits the reaction [Quercetin inhibits the reaction [APP protein results in decreased phosphorylation of CREB1 protein]]decreases phosphorylation|decreases reaction 18001288
C516779 2-(2-(2-dimethylaminothiazol-5-yl)ethenyl)-6-(2-(fluoro)ethoxy)benzoxazole 2-(2-(2-dimethylaminothiazol-5-yl)ethenyl)-6-(2-(fluoro)ethoxy)benzoxazole binds to APP proteinaffects binding 17370645
C440850 2,4,3',5'-tetramethoxystilbene 2,4,3',5'-tetramethoxystilbene results in decreased secretion of APP proteindecreases secretion 16162502
C044563 24-hydroxycholesterol 24-hydroxycholesterol affects the metabolism of and results in increased activity of APP proteinaffects metabolic processing|increases activity 17532301
C044563 24-hydroxycholesterol 24-hydroxycholesterol results in decreased metabolism of and results in decreased secretion of APP proteindecreases metabolic processing|decreases secretion 15148325
C044563 24-hydroxycholesterol 24-hydroxycholesterol results in increased metabolism of APP proteinincreases metabolic processing 19126211
C085911 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[Clioquinol co-treated with Copper] results in decreased expression of APP protein alternative form]affects cotreatment|decreases expression|decreases reaction 16648635
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of APP mRNAaffects expression 21346803
C076996 27-hydroxycholesterol 27-hydroxycholesterol results in decreased metabolism of and results in decreased secretion of APP proteindecreases metabolic processing|decreases secretion 15148325
C076996 27-hydroxycholesterol 27-hydroxycholesterol results in decreased secretion of APP protein alternative formdecreases secretion 19158428
C076996 27-hydroxycholesterol 27-hydroxycholesterol results in increased expression of APP protein alternative formincreases expression 19126211
C076996 27-hydroxycholesterol 27-hydroxycholesterol results in increased expression of APP proteinincreases expression 20157255
C076996 27-hydroxycholesterol 27-hydroxycholesterol results in increased expression of APP protein alternative formincreases expression 18775495
C076996 27-hydroxycholesterol LEP protein inhibits the reaction [27-hydroxycholesterol results in increased expression of APP protein]decreases reaction|increases expression 20157255
C021296 2-ethoxyethanol 2-ethoxyethanol results in increased expression of APP mRNAincreases expression 19643169
C041525 3,3',4,5'-tetrahydroxystilbene 3,3',4,5'-tetrahydroxystilbene results in decreased secretion of APP proteindecreases secretion 16162502
C497286 3,4',5-trimethoxystilbene 3,4',5-trimethoxystilbene results in decreased secretion of APP proteindecreases secretion 16162502
C049017 3-nitrophenol 3-nitrophenol affects the localization of APP proteinaffects localization 18949129
C049017 3-nitrophenol 3-nitrophenol affects the reaction [APP protein affects the abundance of Calcium]affects abundance|affects reaction 18949129
C013813 4-anisidine 4-anisidine affects the localization of APP proteinaffects localization 18949129
C013813 4-anisidine 4-anisidine affects the reaction [APP protein affects the abundance of Calcium]affects abundance|affects reaction 18949129
C027576 4-hydroxy-2-nonenal 4-hydroxy-2-nonenal results in decreased expression of APP mRNAdecreases expression 12419474
C075773 4-phenylbutyric acid 4-phenylbutyric acid affects the activity of APP proteinaffects activity 16204253
C485711 6-(2-fluoroethoxy)-2-(2-(4-methylaminophenil)ethenyl)benzoxazole 6-(2-fluoroethoxy)-2-(2-(4-methylaminophenil)ethenyl)benzoxazole binds to APP proteinaffects binding 17370645
D000109 Acetylcholine APP protein results in decreased secretion of Acetylcholinedecreases secretion 16122837
D000109 Acetylcholine [IL1B protein co-treated with APP protein] results in increased secretion of Acetylcholineaffects cotreatment|increases secretion 16122837
D000109 Acetylcholine IL1B protein inhibits the reaction [APP protein results in decreased secretion of Acetylcholine]decreases reaction|decreases secretion 16122837
D000105 Acetyl Coenzyme A APP protein affects the localization of Acetyl Coenzyme Aaffects localization 16122837
D000105 Acetyl Coenzyme A IL1B protein affects the reaction [APP protein affects the localization of Acetyl Coenzyme A]affects localization|affects reaction 16122837
D000165 Acridine Orange Acridine Orange binds to APP proteinaffects binding 15134570
D000171 Acrolein Acrolein binds to APP proteinaffects binding 16081039
D000171 Acrolein [Acrolein binds to APP protein] binds to [Acrolein binds to APP protein]affects binding 16081039
D000171 Acrolein Acrolein promotes the reaction [APP protein binds to APP protein]affects binding|increases reaction 16081039
D000171 Acrolein APP protein promotes the reaction [Acrolein binds to Acrolein]affects binding|increases reaction 16081039
D000255 Adenosine Triphosphate Adenosine Triphosphate affects the folding of APP proteinaffects folding 10400240
D000255 Adenosine Triphosphate Adenosine Triphosphate promotes the reaction [APP protein binds to APP protein]affects binding|increases reaction 10400240
D013196 Dihydrotestosterone Dihydrotestosterone results in decreased expression of APP mRNAdecreases expression 17023530
C040534 alpha-hexachlorocyclohexane alpha-hexachlorocyclohexane results in increased expression of APP mRNAincreases expression 17785943
D000535 Aluminum APP protein binds to Aluminumaffects binding 16942756
D000535 Aluminum Aluminum results in increased cleavage of APP proteinincreases cleavage 12039845
D000535 Aluminum Aluminum results in increased expression of APP proteinincreases expression 16928369
D000535 Aluminum APP protein promotes the reaction [Aluminum results in decreased activity of CHAT protein]decreases activity|increases reaction 16724269
D000535 Aluminum meloxicam inhibits the reaction [Aluminum results in increased expression of APP protein]decreases reaction|increases expression 16928369
D000535 Aluminum Vitamin E inhibits the reaction [Aluminum results in increased cleavage of APP protein]decreases reaction|increases cleavage 12039845
D000535 Aluminum Aluminum affects the degradation of APP proteinaffects degradation 12446968
C041524 aluminum sulfate aluminum sulfate results in increased expression of APP mRNAincreases expression 15961160
C041524 aluminum sulfate aluminum sulfate affects the expression of APP proteinaffects expression 10721010
C041524 aluminum sulfate aluminum sulfate promotes the reaction [Phosphates affects the folding of APP protein]affects folding|increases reaction 10400240
C041524 aluminum sulfate aluminum sulfate promotes the reaction [Phosphates promotes the reaction [APP protein binds to APP protein]]affects binding|increases reaction 10400240
D000549 Ambenonium Chloride Ambenonium Chloride affects the cleavage of APP proteinaffects cleavage 11099780
D006710 Homocysteine APP protein results in increased abundance of Homocysteineincreases abundance 16837103
D006710 Homocysteine Homocysteine binds to APP proteinaffects binding 16969627
D000640 Amitrole Amitrole affects the activity of APP proteinaffects activity 16204253
D000643 Ammonium Chloride Ammonium Chloride affects the expression of APP mRNAaffects expression 16483693
D000643 Ammonium Chloride Ammonium Chloride results in decreased expression of APP proteindecreases expression 16483693
D000666 Amphotericin B Amphotericin B binds to APP protein alternative formaffects binding 12755626
C432165 anthra(1,9-cd)pyrazol-6(2H)-one anthra(1,9-cd)pyrazol-6(2H)-one inhibits the reaction [[Clioquinol co-treated with Copper] results in decreased expression of APP protein alternative form]affects cotreatment|decreases expression|decreases reaction 16648635
C006632 arsenic trioxide arsenic trioxide results in increased expression of APP mRNAincreases expression 20458559
C005948 astaxanthine astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of APP mRNA]decreases reaction|increases expression 16964424
C006680 baicalein baicalein inhibits the reaction [APP protein binds to APP protein]affects binding|decreases reaction 17323972
D001554 Benzene Benzene analog binds to APP proteinaffects binding 15707952
D001554 Benzene Benzene analog inhibits the reaction [APP protein binds to APP protein]affects binding|decreases reaction 15707952
C517629 benzyloxycarbonyl-valyl-alanyl-aspartic acid benzyloxycarbonyl-valyl-alanyl-aspartic acid inhibits the reaction [Isoflurane affects the expression of APP protein alternative form]affects expression|decreases reaction 17287498
C095105 bexarotene bexarotene results in increased expression of APP mRNAincreases expression 16648578
C073710 bilobalide bilobalide inhibits the reaction [APP protein results in decreased phosphorylation of CREB1 protein]decreases phosphorylation|decreases reaction 18001288
D002038 Bungarotoxins Bungarotoxins inhibits the reaction [Nicotine inhibits the reaction [Copper results in increased expression of APP protein]]decreases reaction|increases expression 16627626
D020001 1-Butanol [1-Butanol results in decreased activity of PLD1 protein] which affects the localization of APP proteinaffects localization|decreases activity 16449385
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in decreased expression of APP mRNAdecreases expression 12419474
D002104 Cadmium Cadmium binds to APP proteinaffects binding 16266835
D002118 Calcium 2,4-Dinitrophenol affects the reaction [APP protein affects the abundance of Calcium]affects abundance|affects reaction 18949129
D002118 Calcium 3-nitrophenol affects the reaction [APP protein affects the abundance of Calcium]affects abundance|affects reaction 18949129
D002118 Calcium 4-anisidine affects the reaction [APP protein affects the abundance of Calcium]affects abundance|affects reaction 18949129
D002118 Calcium APP protein affects the abundance of Calciumaffects abundance 18949129
D002118 Calcium APP protein results in increased uptake of Calciumincreases uptake 12383957
18648507
D002118 Calcium EDN3 protein inhibits the reaction [APP protein results in increased uptake of Calcium]decreases reaction|increases uptake 12383957
D002118 Calcium Flurbiprofen inhibits the reaction [APP protein results in increased uptake of Calcium]decreases reaction|increases uptake 18648507
D002118 Calcium Ibuprofen inhibits the reaction [APP protein results in increased uptake of Calcium]decreases reaction|increases uptake 18648507
D002118 Calcium Indomethacin inhibits the reaction [APP protein results in increased uptake of Calcium]decreases reaction|increases uptake 18648507
D002118 Calcium Nimodipine inhibits the reaction [APP protein results in increased uptake of Calcium]decreases reaction|increases uptake 12383957
D002118 Calcium Salicylates inhibits the reaction [APP protein results in increased uptake of Calcium]decreases reaction|increases uptake 18648507
D002118 Calcium sulindac sulfide inhibits the reaction [APP protein results in increased uptake of Calcium]decreases reaction|increases uptake 18648507
D002251 Carbon Tetrachloride Carbon Tetrachloride results in decreased expression of APP mRNAdecreases expression 17484886
C105934 celecoxib celecoxib affects the cleavage of APP proteinaffects cleavage 14690522
C469298 CEP-11004 CEP-11004 inhibits the reaction [Copper results in increased expression of APP mRNA]decreases reaction|increases expression 18583042
C011724 cholest-5-en-3 beta,7 alpha-diol APP protein results in increased chemical synthesis of cholest-5-en-3 beta,7 alpha-diolincreases chemical synthesis 15591071
C011724 cholest-5-en-3 beta,7 alpha-diol cholest-5-en-3 beta,7 alpha-diol results in decreased secretion of APP proteindecreases secretion 15591071
D002784 Cholesterol [Copper co-treated with Cholesterol] results in increased expression of APP mRNAaffects cotreatment|increases expression 17134702
D002784 Cholesterol Cholesterol promotes the reaction [APP protein affects the localization of Iron]affects localization|increases reaction 17029598
D002784 Cholesterol Cholesterol results in increased expression of APP proteinincreases expression 17029598
D002784 Cholesterol APP protein results in increased oxidation of Cholesterolincreases oxidation 15591071
D002784 Cholesterol Cholesterol affects the folding of and affects the localization of APP proteinaffects folding|affects localization 16689927
D002791 Cholesterol, Dietary Cholesterol, Dietary results in increased expression of APP protein alternative formincreases expression 18775495
C092559 chrysamine G chrysamine G binds to APP proteinaffects binding 15134570
D007464 Clioquinol 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[Clioquinol co-treated with Copper] results in decreased expression of APP protein alternative form]affects cotreatment|decreases expression|decreases reaction 16648635
D007464 Clioquinol anthra(1,9-cd)pyrazol-6(2H)-one inhibits the reaction [[Clioquinol co-treated with Copper] results in decreased expression of APP protein alternative form]affects cotreatment|decreases expression|decreases reaction 16648635
D007464 Clioquinol [Clioquinol co-treated with Copper] results in decreased expression of APP protein alternative formaffects cotreatment|decreases expression 16648635
D007464 Clioquinol Clioquinol inhibits the reaction [Copper results in increased secretion of APP protein alternative form]decreases reaction|increases secretion 16648635
D007464 Clioquinol Clioquinol inhibits the reaction [Zinc results in increased secretion of APP protein alternative form]decreases reaction|increases secretion 16648635
D002995 Clofibric Acid [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of APP mRNAaffects cotreatment|affects expression 17602206
D003224 Congo Red Congo Red binds to APP proteinaffects binding 17406451
D003224 Congo Red Congo Red inhibits the reaction [APP protein binds to APP protein]affects binding|decreases reaction 17323972
D003224 Congo Red Congo Red binds to APP proteinaffects binding 15134570
D003300 Copper Copper results in increased expression of APP proteinincreases expression 16886094
D003300 Copper 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[Clioquinol co-treated with Copper] results in decreased expression of APP protein alternative form]affects cotreatment|decreases expression|decreases reaction 16648635
D003300 Copper anthra(1,9-cd)pyrazol-6(2H)-one inhibits the reaction [[Clioquinol co-treated with Copper] results in decreased expression of APP protein alternative form]affects cotreatment|decreases expression|decreases reaction 16648635
D003300 Copper Bungarotoxins inhibits the reaction [Nicotine inhibits the reaction [Copper results in increased expression of APP protein]]decreases reaction|increases expression 16627626
D003300 Copper CEP-11004 inhibits the reaction [Copper results in increased expression of APP mRNA]decreases reaction|increases expression 18583042
D003300 Copper [Clioquinol co-treated with Copper] results in decreased expression of APP protein alternative formaffects cotreatment|decreases expression 16648635
D003300 Copper Clioquinol inhibits the reaction [Copper results in increased secretion of APP protein alternative form]decreases reaction|increases secretion 16648635
D003300 Copper Copper binds to and affects the folding of APP proteinaffects binding|affects folding 16325427
D003300 Copper Copper binds to APP proteinaffects binding 17239395
17119284
D003300 Copper Copper binds to APP protein alternative formaffects binding 15699049
D003300 Copper [Copper binds to APP protein alternative form] which results in increased oxidation of Pyrogallolaffects binding|increases oxidation 15699049
D003300 Copper Copper promotes the reaction [APP protein binds to APP protein]affects binding|increases reaction 16627626
D003300 Copper Copper results in increased expression of APP mRNAincreases expression 16627626
16962711
18583042
D003300 Copper Copper results in increased expression of APP proteinincreases expression 16627626
16962711
D003300 Copper Copper results in increased secretion of APP proteinincreases secretion 16962711
D003300 Copper Copper results in increased secretion of APP protein alternative formincreases secretion 16648635
D003300 Copper Curcumin inhibits the reaction [Copper results in increased expression of APP mRNA]decreases reaction|increases expression 18583042
D003300 Copper Hydrogen Peroxide promotes the reaction [[Copper binds to APP protein alternative form] which results in increased oxidation of Pyrogallol]affects binding|increases oxidation|increases reaction 15699049
D003300 Copper Mecamylamine inhibits the reaction [Nicotine inhibits the reaction [Copper results in increased expression of APP protein]]decreases reaction|increases expression 16627626
D003300 Copper Nicotine inhibits the reaction [Copper promotes the reaction [APP protein binds to APP protein]]affects binding|decreases reaction|increases reaction 16627626
D003300 Copper Nicotine inhibits the reaction [Copper results in increased expression of APP mRNA]decreases reaction|increases expression 16627626
D003300 Copper Nicotine inhibits the reaction [Copper results in increased expression of APP protein]decreases reaction|increases expression 16627626
D003300 Copper PD 98059 inhibits the reaction [Copper results in increased expression of APP mRNA]decreases reaction|increases expression 18583042
D003300 Copper Plant Extracts inhibits the reaction [Copper results in increased expression of APP mRNA]decreases reaction|increases expression 16962711
D003300 Copper Plant Extracts inhibits the reaction [Copper results in increased expression of APP protein]decreases reaction|increases expression 16962711
D003300 Copper Plant Extracts inhibits the reaction [Copper results in increased secretion of APP protein]decreases reaction|increases secretion 16962711
D003300 Copper SB 203580 inhibits the reaction [Copper results in increased expression of APP mRNA]decreases reaction|increases expression 18583042
D003300 Copper APP protein results in increased secretion of Copperincreases secretion 16866297
D003300 Copper [Copper co-treated with Cholesterol] results in increased expression of APP mRNAaffects cotreatment|increases expression 17134702
D003300 Copper Copper results in increased expression of APP proteinincreases expression 16886094
D003300 Copper Copper results in increased expression of APP proteinincreases expression 16886094
D003300 Copper APP protein affects the transport of Copperaffects transport 17239395
D003300 Copper [APP protein binds to Copper] which results in increased abundance of Hydrogen Peroxideaffects binding|increases abundance 17277887
D003300 Copper Copper binds to APP proteinaffects binding 7913895
17277887
D003300 Copper Copper inhibits the reaction [APP protein binds to APP protein]affects binding|decreases reaction 7913895
D003300 Copper Copper results in decreased expression of APP proteindecreases expression 17239395
D003474 Curcumin Curcumin affects the reaction [APP protein binds to APP protein]affects binding|affects reaction 18537544
D003474 Curcumin Curcumin inhibits the reaction [Copper results in increased expression of APP mRNA]decreases reaction|increases expression 18583042
D003474 Curcumin Curcumin binds to APP proteinaffects binding 15590663
D003474 Curcumin Curcumin inhibits the reaction [APP protein binds to APP protein]affects binding|decreases reaction 15590663
D003474 Curcumin Curcumin results in decreased activity of [Heme binds to APP protein]affects binding|decreases activity 16492752
C009160 cyclonite cyclonite results in decreased expression of APP mRNAdecreases expression 19417177
D003847 Deoxyglucose [Sodium Azide co-treated with Deoxyglucose] affects the cleavage of and affects the localization of APP proteinaffects cleavage|affects cotreatment|affects localization 17405930
D004006 Dichlorvos Dichlorvos results in increased secretion of APP protein alternative formincreases secretion 11526466
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of APP mRNAaffects cotreatment|affects expression 17602206
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of APP mRNAincreases expression 19638242
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of APP proteinincreases expression 19542621
20387270
D004295 Dihydroxyphenylalanine [Heme binds to APP protein] which results in increased oxidation of Dihydroxyphenylalanineaffects binding|increases oxidation 16492752
D016291 Dizocilpine Maleate Dizocilpine Maleate inhibits the reaction [Pentylenetetrazole results in increased expression of APP mRNA]decreases reaction|increases expression 9720974
D019297 2,4-Dinitrophenol 2,4-Dinitrophenol affects the localization of APP proteinaffects localization 18949129
D019297 2,4-Dinitrophenol 2,4-Dinitrophenol affects the reaction [APP protein affects the abundance of Calcium]affects abundance|affects reaction 18949129
D004317 Doxorubicin APP protein affects the susceptibility to Doxorubicinaffects response to substance 17608641
D004317 Doxorubicin TP53 protein affects the reaction [APP protein affects the susceptibility to Doxorubicin]affects reaction|affects response to substance 17608641
C514017 DP 155 DP 155 results in decreased expression of APP protein alternative formdecreases expression 17627676
C044101 endotoxin, Escherichia coli endotoxin, Escherichia coli results in increased expression of APP mRNAincreases expression 15919760
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of APP mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of APP mRNAdecreases expression 19400957
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of APP mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of APP mRNAaffects cotreatment|decreases expression 17942748
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of APP mRNAdecreases expression 19400957
C015881 farrerol farrerol inhibits the reaction [APP protein binds to APP protein]affects binding|decreases reaction 17323972
D011345 Fenofibrate Fenofibrate affects the reaction [PSEN1 protein affects the cleavage of APP protein]affects cleavage|affects reaction 17962197
D005480 Flurbiprofen Flurbiprofen affects the cleavage of APP proteinaffects cleavage 15340006
D005480 Flurbiprofen Flurbiprofen affects the cleavage of APP proteinaffects cleavage 14690522
D005480 Flurbiprofen Flurbiprofen inhibits the reaction [APP protein results in increased uptake of Calcium]decreases reaction|increases uptake 18648507
D005480 Flurbiprofen Flurbiprofen analog results in decreased expression of APP proteindecreases expression 16455248
C056933 fumonisin B1 fumonisin B1 results in increased expression of APP mRNAincreases expression 16221962
C063170 Ginkgo biloba extract 761 1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one inhibits the reaction [Ginkgo biloba extract 761 inhibits the reaction [APP protein results in decreased phosphorylation of CREB1 protein]]decreases phosphorylation|decreases reaction 18001288
C063170 Ginkgo biloba extract 761 Ginkgo biloba extract 761 inhibits the reaction [APP protein results in decreased expression of BDNF protein]decreases expression|decreases reaction 18001288
C063170 Ginkgo biloba extract 761 Ginkgo biloba extract 761 inhibits the reaction [APP protein results in decreased phosphorylation of CREB1 protein]decreases phosphorylation|decreases reaction 18001288
C063170 Ginkgo biloba extract 761 Ginkgo biloba extract 761 inhibits the reaction [APP protein results in increased abundance of Reactive Oxygen Species]decreases reaction|increases abundance 19464278
C063170 Ginkgo biloba extract 761 Ginkgo biloba extract 761 inhibits the reaction [APP protein results in increased cleavage of and results in increased activity of CASP3 protein]decreases reaction|increases activity|increases cleavage 19464278
C063170 Ginkgo biloba extract 761 Ginkgo biloba extract 761 inhibits the reaction [APP protein results in increased phosphorylation of and results in increased activity of AKT1 protein]decreases reaction|increases activity|increases phosphorylation 19464278
C063170 Ginkgo biloba extract 761 Ginkgo biloba extract 761 inhibits the reaction [APP protein results in increased phosphorylation of and results in increased activity of MAPK1 protein]decreases reaction|increases activity|increases phosphorylation 19464278
C063170 Ginkgo biloba extract 761 Ginkgo biloba extract 761 inhibits the reaction [APP protein results in increased phosphorylation of and results in increased activity of MAPK3 protein]decreases reaction|increases activity|increases phosphorylation 19464278
C063170 Ginkgo biloba extract 761 Ginkgo biloba extract 761 inhibits the reaction [APP protein results in increased phosphorylation of and results in increased activity of MAPK8 protein]decreases reaction|increases activity|increases phosphorylation 19464278
C063170 Ginkgo biloba extract 761 KT 5823 inhibits the reaction [Ginkgo biloba extract 761 inhibits the reaction [APP protein results in decreased phosphorylation of CREB1 protein]]decreases phosphorylation|decreases reaction 18001288
C063170 Ginkgo biloba extract 761 PD 98059 inhibits the reaction [Ginkgo biloba extract 761 inhibits the reaction [APP protein results in decreased phosphorylation of CREB1 protein]]decreases phosphorylation|decreases reaction 18001288
C063170 Ginkgo biloba extract 761 Staurosporine inhibits the reaction [Ginkgo biloba extract 761 inhibits the reaction [APP protein results in decreased phosphorylation of CREB1 protein]]decreases phosphorylation|decreases reaction 18001288
C045856 ginkgolide B ginkgolide B inhibits the reaction [APP protein results in increased abundance of Reactive Oxygen Species]decreases reaction|increases abundance 19464278
C045856 ginkgolide B ginkgolide B inhibits the reaction [APP protein results in increased cleavage of and results in increased activity of CASP3 protein]decreases reaction|increases activity|increases cleavage 19464278
C045856 ginkgolide B ginkgolide B inhibits the reaction [APP protein results in increased phosphorylation of and results in increased activity of AKT1 protein]decreases reaction|increases activity|increases phosphorylation 19464278
C045856 ginkgolide B ginkgolide B inhibits the reaction [APP protein results in increased phosphorylation of and results in increased activity of MAPK1 protein]decreases reaction|increases activity|increases phosphorylation 19464278
C045856 ginkgolide B ginkgolide B inhibits the reaction [APP protein results in increased phosphorylation of and results in increased activity of MAPK3 protein]decreases reaction|increases activity|increases phosphorylation 19464278
C045856 ginkgolide B ginkgolide B inhibits the reaction [APP protein results in increased phosphorylation of and results in increased activity of MAPK8 protein]decreases reaction|increases activity|increases phosphorylation 19464278
C058295 ginkgolide C 1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one inhibits the reaction [ginkgolide C inhibits the reaction [APP protein results in decreased phosphorylation of CREB1 protein]]decreases phosphorylation|decreases reaction 18001288
C058295 ginkgolide C ginkgolide C inhibits the reaction [APP protein results in decreased phosphorylation of CREB1 protein]decreases phosphorylation|decreases reaction 18001288
C058295 ginkgolide C KT 5823 inhibits the reaction [ginkgolide C inhibits the reaction [APP protein results in decreased phosphorylation of CREB1 protein]]decreases phosphorylation|decreases reaction 18001288
C058295 ginkgolide C PD 98059 inhibits the reaction [ginkgolide C inhibits the reaction [APP protein results in decreased phosphorylation of CREB1 protein]]decreases phosphorylation|decreases reaction 18001288
C433283 glycitin glycitin inhibits the reaction [APP protein binds to APP protein]affects binding|decreases reaction 17323972
C078131 GM 6001 GM 6001 results in decreased secretion of APP protein alternative formdecreases secretion 16279945
D006418 Heme Curcumin results in decreased activity of [Heme binds to APP protein]affects binding|decreases activity 16492752
D006418 Heme Heme binds to APP proteinaffects binding 16492752
D006418 Heme [Heme binds to APP protein] which results in increased oxidation of Dihydroxyphenylalanineaffects binding|increases oxidation 16492752
D006418 Heme [Heme binds to APP protein] which results in increased oxidation of Serotoninaffects binding|increases oxidation 16492752
D006493 Heparin Heparin binds to APP proteinaffects binding 9453569
D006493 Heparin Heparin, Low-Molecular-Weight inhibits the reaction [Heparin binds to APP protein]affects binding|decreases reaction 9453569
D006493 Heparin Heparin, Low-Molecular-Weight inhibits the reaction [Heparin results in increased secretion of APP protein]decreases reaction|increases secretion 9453569
D006493 Heparin Heparin results in increased expression of and results in increased secretion of APP proteinincreases expression|increases secretion 9453569
D006495 Heparin, Low-Molecular-Weight Heparin, Low-Molecular-Weight inhibits the reaction [Heparin binds to APP protein]affects binding|decreases reaction 9453569
D006495 Heparin, Low-Molecular-Weight Heparin, Low-Molecular-Weight inhibits the reaction [Heparin results in increased secretion of APP protein]decreases reaction|increases secretion 9453569
C098514 hexadecyl-N-methylpiperidinium hexadecyl-N-methylpiperidinium binds to APP proteinaffects binding 8626745
C098514 hexadecyl-N-methylpiperidinium hexadecyl-N-methylpiperidinium inhibits the reaction [APP protein binds to APP protein]affects binding|decreases reaction 8626745
C087346 hibifolin hibifolin inhibits the reaction [APP protein binds to APP protein]affects binding|decreases reaction 17323972
D006861 Hydrogen Peroxide Hydrogen Peroxide promotes the reaction [[Copper binds to APP protein alternative form] which results in increased oxidation of Pyrogallol]affects binding|increases oxidation|increases reaction 15699049
D006861 Hydrogen Peroxide Hydrogen Peroxide results in increased expression of APP mRNAincreases expression 12419474
D006861 Hydrogen Peroxide [APP protein binds to Copper] which results in increased abundance of Hydrogen Peroxideaffects binding|increases abundance 17277887
D012701 Serotonin [Heme binds to APP protein] which results in increased oxidation of Serotoninaffects binding|increases oxidation 16492752
D007052 Ibuprofen Ibuprofen affects the cleavage of APP proteinaffects cleavage 12777371
11700559
D007052 Ibuprofen Ibuprofen inhibits the reaction [[IFNG protein co-treated with IL1B protein] results in increased metabolism of and results in increased secretion of APP protein alternative form]affects cotreatment|decreases reaction|increases metabolic processing|increases secretion 14586007
D007052 Ibuprofen Ibuprofen inhibits the reaction [[IFNG protein co-treated with TNF protein] results in increased metabolism of and results in increased secretion of APP protein alternative form]affects cotreatment|decreases reaction|increases metabolic processing|increases secretion 14586007
D007052 Ibuprofen Ibuprofen results in decreased expression of APP protein mutant formdecreases expression 15817521
D007052 Ibuprofen Ibuprofen inhibits the reaction [[APP protein co-treated with IFNG protein] results in increased abundance of Nitric Oxide]affects cotreatment|decreases reaction|increases abundance 11080519
D007052 Ibuprofen Ibuprofen inhibits the reaction [[APP protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]affects cotreatment|decreases reaction|increases expression 11080519
D007052 Ibuprofen Ibuprofen inhibits the reaction [APP protein results in increased uptake of Calcium]decreases reaction|increases uptake 18648507
C056599 icariin icariin inhibits the reaction [APP protein alternative form results in decreased expression of SOD2 mRNA]decreases expression|decreases reaction 19782061
C056599 icariin icariin inhibits the reaction [APP protein alternative form results in increased expression of BACE1 mRNA]decreases reaction|increases expression 19782061
D007213 Indomethacin Indomethacin affects the cleavage of APP proteinaffects cleavage 11700559
D007213 Indomethacin Indomethacin inhibits the reaction [APP protein alternative form results in increased expression of IL6 protein]decreases reaction|increases expression 16111494
D007213 Indomethacin Indomethacin inhibits the reaction [[IFNG protein co-treated with TNF protein] results in increased metabolism of and results in increased secretion of APP protein alternative form]affects cotreatment|decreases reaction|increases metabolic processing|increases secretion 14586007
D007213 Indomethacin Indomethacin inhibits the reaction [[APP protein co-treated with IFNG protein] results in increased abundance of Nitric Oxide]affects cotreatment|decreases reaction|increases abundance 11080519
D007213 Indomethacin Indomethacin inhibits the reaction [[APP protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]affects cotreatment|decreases reaction|increases expression 11080519
D007213 Indomethacin Indomethacin results in decreased expression of APP protein alternative formdecreases expression 17627676
15579461
D007213 Indomethacin Indomethacin inhibits the reaction [APP protein results in increased uptake of Calcium]decreases reaction|increases uptake 18648507
D007501 Iron Iron results in increased uptake of APP proteinincreases uptake 15993987
D007501 Iron Cholesterol promotes the reaction [APP protein affects the localization of Iron]affects localization|increases reaction 17029598
D007501 Iron Iron binds to APP proteinaffects binding 11182300
D007530 Isoflurane APP protein promotes the reaction [Isoflurane results in increased cleavage of and results in increased activity of CASP3 protein]increases activity|increases cleavage|increases reaction 17287498
D007530 Isoflurane benzyloxycarbonyl-valyl-alanyl-aspartic acid inhibits the reaction [Isoflurane affects the expression of APP protein alternative form]affects expression|decreases reaction 17287498
D007530 Isoflurane Isoflurane affects the metabolism of and affects the expression of and affects the secretion of APP protein alternative formaffects expression|affects metabolic processing|affects secretion 17287498
C006552 kaempferol kaempferol inhibits the reaction [APP protein binds to APP protein]affects binding|decreases reaction 17323972
D007657 Ketone Bodies Ketone Bodies results in increased expression of APP mRNAincreases expression 16807920
C011890 kojic acid kojic acid results in increased expression of APP mRNAincreases expression 16595896
C073601 KT 5823 KT 5823 inhibits the reaction [Ginkgo biloba extract 761 inhibits the reaction [APP protein results in decreased phosphorylation of CREB1 protein]]decreases phosphorylation|decreases reaction 18001288
C073601 KT 5823 KT 5823 inhibits the reaction [ginkgolide C inhibits the reaction [APP protein results in decreased phosphorylation of CREB1 protein]]decreases phosphorylation|decreases reaction 18001288
C073601 KT 5823 KT 5823 inhibits the reaction [Quercetin inhibits the reaction [APP protein results in decreased phosphorylation of CREB1 protein]]decreases phosphorylation|decreases reaction 18001288
C067713 lactacystin lactacystin inhibits the reaction [resveratrol results in decreased secretion of APP protein]decreases reaction|decreases secretion 16162502
D007854 Lead Lead affects the abundance of APP mRNAaffects abundance 16230335
D007854 Lead Lead affects the abundance of APP proteinaffects abundance 16230335
D007854 Lead Lead affects the reaction [APP protein binds to APP protein]affects binding|affects reaction 16230335
D008070 Lipopolysaccharides Lipopolysaccharides results in increased expression of APP mRNAincreases expression 15919760
D008094 Lithium Lithium inhibits the reaction [APP protein binds to APP protein]affects binding|decreases reaction 19621015
D008345 Manganese Manganese results in increased expression of APP mRNAincreases expression 18583042
D008464 Mecamylamine Mecamylamine inhibits the reaction [Nicotine inhibits the reaction [Copper results in increased expression of APP protein]]decreases reaction|increases expression 16627626
D008550 Melatonin Melatonin affects the reaction [APP protein binds to APP protein]affects binding|affects reaction 18537544
D008550 Melatonin Melatonin analog results in decreased expression of APP proteindecreases expression 18231852
D008550 Melatonin Melatonin results in decreased expression of APP proteindecreases expression 18231852
C065757 meloxicam meloxicam inhibits the reaction [Aluminum results in increased expression of APP protein]decreases reaction|increases expression 16928369
D008713 Methimazole Methimazole results in decreased expression of APP mRNAdecreases expression 17403546
D008713 Methimazole Methimazole results in increased expression of APP mRNAincreases expression 17403546
C005219 methyl cellosolve methyl cellosolve results in increased expression of APP mRNAincreases expression 19643169
D016685 Mitomycin Mitomycin results in increased expression of APP mRNAincreases expression 12760830
C008548 morin morin affects the reaction [APP protein binds to APP protein]affects binding|affects reaction 18537544
D009151 Mustard Gas Mustard Gas results in decreased expression of APP mRNAdecreases expression 15674843
C484278 N2-((2S)-2-(3,5-difluorophenyl)-2-hydroxyethanoyl)-N1-((7S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)-L-alaninamide N2-((2S)-2-(3,5-difluorophenyl)-2-hydroxyethanoyl)-N1-((7S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)-L-alaninamide affects the cleavage of APP proteinaffects cleavage 15340006
D019810 Sodium Azide [Sodium Azide co-treated with Deoxyglucose] affects the cleavage of and affects the localization of APP proteinaffects cleavage|affects cotreatment|affects localization 17405930
C495708 N-benzyloxycarbonyl-valyl-leucyl-leucinal N-benzyloxycarbonyl-valyl-leucyl-leucinal results in decreased secretion of APP protein alternative formdecreases secretion 16279945
D009532 Nickel Nickel binds to APP protein alternative formaffects binding 15699049
D009538 Nicotine Bungarotoxins inhibits the reaction [Nicotine inhibits the reaction [Copper results in increased expression of APP protein]]decreases reaction|increases expression 16627626
D009538 Nicotine Mecamylamine inhibits the reaction [Nicotine inhibits the reaction [Copper results in increased expression of APP protein]]decreases reaction|increases expression 16627626
D009538 Nicotine Nicotine inhibits the reaction [Copper promotes the reaction [APP protein binds to APP protein]]affects binding|decreases reaction|increases reaction 16627626
D009538 Nicotine Nicotine inhibits the reaction [Copper results in increased expression of APP mRNA]decreases reaction|increases expression 16627626
D009538 Nicotine Nicotine inhibits the reaction [Copper results in increased expression of APP protein]decreases reaction|increases expression 16627626
D009538 Nicotine Nicotine results in decreased expression of APP mRNAdecreases expression 16627626
D009538 Nicotine Nicotine results in decreased expression of APP proteindecreases expression 16627626
D009553 Nimodipine Nimodipine inhibits the reaction [APP protein results in increased uptake of Calcium]decreases reaction|increases uptake 12383957
D009569 Nitric Oxide [APP protein co-treated with IFNG protein] results in increased abundance of Nitric Oxideaffects cotreatment|increases abundance 11080519
D009569 Nitric Oxide Ibuprofen inhibits the reaction [[APP protein co-treated with IFNG protein] results in increased abundance of Nitric Oxide]affects cotreatment|decreases reaction|increases abundance 11080519
D009569 Nitric Oxide Indomethacin inhibits the reaction [[APP protein co-treated with IFNG protein] results in increased abundance of Nitric Oxide]affects cotreatment|decreases reaction|increases abundance 11080519
D009599 Nitroprusside APP protein promotes the reaction [Nitroprusside results in decreased activity of CHAT protein]decreases activity|increases reaction 16724269
C419410 N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester affects the cleavage of APP proteinaffects cleavage 15340006
D010126 Ozone [Ozone co-treated with Particulate Matter] results in increased expression of APP proteinaffects cotreatment|increases expression 15513908
D052638 Particulate Matter [Ozone co-treated with Particulate Matter] results in increased expression of APP proteinaffects cotreatment|increases expression 15513908
C093973 PD 98059 PD 98059 inhibits the reaction [Copper results in increased expression of APP mRNA]decreases reaction|increases expression 18583042
C093973 PD 98059 PD 98059 inhibits the reaction [Ginkgo biloba extract 761 inhibits the reaction [APP protein results in decreased phosphorylation of CREB1 protein]]decreases phosphorylation|decreases reaction 18001288
C093973 PD 98059 PD 98059 inhibits the reaction [ginkgolide C inhibits the reaction [APP protein results in decreased phosphorylation of CREB1 protein]]decreases phosphorylation|decreases reaction 18001288
D010424 Pentobarbital Pentobarbital affects the expression of APP mRNAaffects expression 1306490
D010424 Pentobarbital Pentobarbital inhibits the reaction [Pentylenetetrazole results in increased expression of APP mRNA]decreases reaction|increases expression 9720974
D010433 Pentylenetetrazole Dizocilpine Maleate inhibits the reaction [Pentylenetetrazole results in increased expression of APP mRNA]decreases reaction|increases expression 9720974
D010433 Pentylenetetrazole Pentobarbital inhibits the reaction [Pentylenetetrazole results in increased expression of APP mRNA]decreases reaction|increases expression 9720974
D010433 Pentylenetetrazole Pentylenetetrazole results in increased expression of APP mRNAincreases expression 9720974
C494474 perchlorate perchlorate results in decreased expression of APP mRNAdecreases expression 17403546
C494474 perchlorate perchlorate results in increased expression of APP mRNAincreases expression 17403546
D010710 Phosphates aluminum sulfate promotes the reaction [Phosphates affects the folding of APP protein]affects folding|increases reaction 10400240
D010710 Phosphates aluminum sulfate promotes the reaction [Phosphates promotes the reaction [APP protein binds to APP protein]]affects binding|increases reaction 10400240
D010710 Phosphates Phosphates affects the folding of APP proteinaffects folding 10400240
D010710 Phosphates Phosphates promotes the reaction [APP protein binds to APP protein]affects binding|increases reaction 10400240
D010710 Phosphates tris(acetylacetonate) aluminum(III) promotes the reaction [Phosphates affects the folding of APP protein]affects folding|increases reaction 10400240
D010710 Phosphates tris(acetylacetonate) aluminum(III) promotes the reaction [Phosphates promotes the reaction [APP protein binds to APP protein]]affects binding|increases reaction 10400240
C060836 pioglitazone pioglitazone inhibits the reaction [[IFNG protein co-treated with IL1B protein] results in increased metabolism of and results in increased secretion of APP protein alternative form]affects cotreatment|decreases reaction|increases metabolic processing|increases secretion 14586007
C060836 pioglitazone pioglitazone inhibits the reaction [[IFNG protein co-treated with TNF protein] results in increased metabolism of and results in increased secretion of APP protein alternative form]affects cotreatment|decreases reaction|increases metabolic processing|increases secretion 14586007
C060836 pioglitazone pioglitazone results in decreased expression of APP protein mutant formdecreases expression 15817521
C060836 pioglitazone pioglitazone results in decreased expression of APP proteindecreases expression 16407166
C032727 piperidine piperidine analog inhibits the reaction [ACHE protein promotes the reaction [APP protein binds to APP protein]]affects binding|decreases reaction|increases reaction 17681794
C032727 piperidine piperidine analog inhibits the reaction [APP protein binds to APP protein]affects binding|decreases reaction 17681794
C006253 pirinixic acid pirinixic acid results in decreased expression of APP mRNAdecreases expression 17426115
C006253 pirinixic acid pirinixic acid affects the activity of APP proteinaffects activity 16204253
C006253 pirinixic acid pirinixic acid inhibits the reaction [APP protein results in decreased activity of CAT protein]decreases activity|decreases reaction 16204253
C006253 pirinixic acid pirinixic acid inhibits the reaction [APP protein results in decreased expression of CTNNB1 protein]decreases expression|decreases reaction 16204253
D010936 Plant Extracts Plant Extracts inhibits the reaction [Copper results in increased expression of APP mRNA]decreases reaction|increases expression 16962711
D010936 Plant Extracts Plant Extracts inhibits the reaction [Copper results in increased expression of APP protein]decreases reaction|increases expression 16962711
D010936 Plant Extracts Plant Extracts inhibits the reaction [Copper results in increased secretion of APP protein]decreases reaction|increases secretion 16962711
D010936 Plant Extracts Plant Extracts results in decreased expression of APP mRNAdecreases expression 16962711
D010936 Plant Extracts Plant Extracts results in decreased expression of APP proteindecreases expression 16962711
D010936 Plant Extracts Plant Extracts results in decreased secretion of APP proteindecreases secretion 16962711
D010936 Plant Extracts Plant Extracts inhibits the reaction [APP protein alternative form results in increased activity of CASP2 protein]decreases reaction|increases activity 16406021
D010936 Plant Extracts Plant Extracts inhibits the reaction [APP protein alternative form results in increased activity of CASP3 protein]decreases reaction|increases activity 16406021
D010936 Plant Extracts Plant Extracts inhibits the reaction [APP protein alternative form results in increased phosphorylation of MAPK8 protein]decreases reaction|increases phosphorylation 16406021
D010936 Plant Extracts Plant Extracts inhibits the reaction [APP protein alternative form results in increased phosphorylation of PKR protein]decreases reaction|increases phosphorylation 16406021
D011188 Potassium [Zinc promotes the reaction [APP protein binds to APP protein]] which affects the transport of Potassiumaffects binding|affects transport|increases reaction 16674922
D011374 Progesterone APP gene mutant form results in decreased metabolism of Progesterone metabolitedecreases metabolic processing 17988898
D011374 Progesterone Progesterone inhibits the reaction [APP gene mutant form results in decreased metabolism of Progesterone metabolite]decreases metabolic processing|decreases reaction 17988898
C045950 propiconazole propiconazole results in increased expression of APP mRNAincreases expression 19423681
D011441 Propylthiouracil Propylthiouracil results in decreased expression of APP mRNAdecreases expression 17403546
D011441 Propylthiouracil Propylthiouracil results in increased expression of APP mRNAincreases expression 17403546
D015232 Dinoprostone resveratrol inhibits the reaction [APP protein results in increased secretion of Dinoprostone]decreases reaction|increases secretion 16685418
D011748 Pyrogallol [Copper binds to APP protein alternative form] which results in increased oxidation of Pyrogallolaffects binding|increases oxidation 15699049
D011748 Pyrogallol Hydrogen Peroxide promotes the reaction [[Copper binds to APP protein alternative form] which results in increased oxidation of Pyrogallol]affects binding|increases oxidation|increases reaction 15699049
D011794 Quercetin 1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one inhibits the reaction [Quercetin inhibits the reaction [APP protein results in decreased phosphorylation of CREB1 protein]]decreases phosphorylation|decreases reaction 18001288
D011794 Quercetin KT 5823 inhibits the reaction [Quercetin inhibits the reaction [APP protein results in decreased phosphorylation of CREB1 protein]]decreases phosphorylation|decreases reaction 18001288
D011794 Quercetin Quercetin inhibits the reaction [APP protein results in decreased phosphorylation of CREB1 protein]decreases phosphorylation|decreases reaction 18001288
D011794 Quercetin Quercetin inhibits the reaction [APP protein results in increased abundance of Reactive Oxygen Species]decreases reaction|increases abundance 19464278
D011794 Quercetin Quercetin inhibits the reaction [APP protein results in increased cleavage of and results in increased activity of CASP3 protein]decreases reaction|increases activity|increases cleavage 19464278
D011794 Quercetin Quercetin inhibits the reaction [APP protein results in increased phosphorylation of and results in increased activity of AKT1 protein]decreases reaction|increases activity|increases phosphorylation 19464278
D011794 Quercetin Quercetin inhibits the reaction [APP protein results in increased phosphorylation of and results in increased activity of MAPK1 protein]decreases reaction|increases activity|increases phosphorylation 19464278
D011794 Quercetin Quercetin inhibits the reaction [APP protein results in increased phosphorylation of and results in increased activity of MAPK3 protein]decreases reaction|increases activity|increases phosphorylation 19464278
D011794 Quercetin Quercetin inhibits the reaction [APP protein results in increased phosphorylation of and results in increased activity of MAPK8 protein]decreases reaction|increases activity|increases phosphorylation 19464278
C532085 quercetin 3'-O-glucoside quercetin 3'-O-glucoside inhibits the reaction [APP protein binds to APP protein]affects binding|decreases reaction 17323972
D011803 Quinine Quinine affects the reaction [APP protein binds to APP protein]affects binding|affects reaction 18537544
D017382 Reactive Oxygen Species APP protein results in increased abundance of Reactive Oxygen Speciesincreases abundance 19464278
D017382 Reactive Oxygen Species Ginkgo biloba extract 761 inhibits the reaction [APP protein results in increased abundance of Reactive Oxygen Species]decreases reaction|increases abundance 19464278
D017382 Reactive Oxygen Species ginkgolide B inhibits the reaction [APP protein results in increased abundance of Reactive Oxygen Species]decreases reaction|increases abundance 19464278
D017382 Reactive Oxygen Species Quercetin inhibits the reaction [APP protein results in increased abundance of Reactive Oxygen Species]decreases reaction|increases abundance 19464278
C059514 resveratrol lactacystin inhibits the reaction [resveratrol results in decreased secretion of APP protein]decreases reaction|decreases secretion 16162502
C059514 resveratrol PSMB5 protein affects the reaction [resveratrol results in decreased secretion of APP protein]affects reaction|decreases secretion 16162502
C059514 resveratrol resveratrol binds to [APP protein binds to APP protein]affects binding 17597573
C059514 resveratrol resveratrol inhibits the reaction [APP protein results in increased abundance of Superoxides]decreases reaction|increases abundance 16212921
C059514 resveratrol resveratrol results in decreased secretion of and results in increased degradation of APP proteindecreases secretion|increases degradation 16162502
C059514 resveratrol YU101 inhibits the reaction [resveratrol results in decreased secretion of APP protein]decreases reaction|decreases secretion 16162502
C059514 resveratrol resveratrol results in decreased secretion of APP protein mutant formdecreases secretion 16162502
C059514 resveratrol resveratrol inhibits the reaction [APP protein results in increased acetylation of RELA protein]decreases reaction|increases acetylation 16183991
C059514 resveratrol resveratrol inhibits the reaction [APP protein results in increased expression of and results in increased activity of NOS2 protein]decreases reaction|increases activity|increases expression 16685418
C059514 resveratrol resveratrol inhibits the reaction [APP protein results in increased expression of PTGS2 protein]decreases reaction|increases expression 16685418
C059514 resveratrol resveratrol inhibits the reaction [APP protein results in increased secretion of Dinoprostone]decreases reaction|increases secretion 16685418
C089730 rosiglitazone rosiglitazone inhibits the reaction [APP protein binds to APP protein]affects binding|decreases reaction 19621015
D012459 Salicylates Salicylates inhibits the reaction [APP protein results in increased uptake of Calcium]decreases reaction|increases uptake 18648507
C093642 SB 203580 SB 203580 inhibits the reaction [Copper results in increased expression of APP mRNA]decreases reaction|increases expression 18583042
C115461 SC 560 SC 560 affects the cleavage of APP proteinaffects cleavage 14690522
C484876 scutellarin scutellarin inhibits the reaction [APP protein binds to APP protein]affects binding|decreases reaction 17323972
D012643 Selenium Selenium results in decreased expression of APP mRNAdecreases expression 19244175
D012645 Selenomethionine Selenomethionine inhibits the reaction [APP protein results in decreased expression of and results in decreased activity of GPX1 protein]decreases activity|decreases expression|decreases reaction 17280487
C017947 sodium arsenite sodium arsenite results in increased expression of APP mRNAincreases expression 12760830
D013109 Sphingomyelins Sphingomyelins affects the folding of and affects the localization of APP proteinaffects folding|affects localization 16689927
D019311 Staurosporine Staurosporine inhibits the reaction [Ginkgo biloba extract 761 inhibits the reaction [APP protein results in decreased phosphorylation of CREB1 protein]]decreases phosphorylation|decreases reaction 18001288
D019311 Staurosporine Staurosporine promotes the reaction [PSEN2 protein mutant form results in increased expression of APP protein]increases expression|increases reaction 12556443
D013467 Sulindac Sulindac affects the cleavage of APP proteinaffects cleavage 15340006
D013467 Sulindac Sulindac inhibits the reaction [CDKN1A protein results in increased expression of APP mRNA]decreases reaction|increases expression 15190207
C025462 sulindac sulfide PSEN1 protein affects the reaction [sulindac sulfide affects the cleavage of APP protein]affects cleavage|affects reaction 12805356
C025462 sulindac sulfide PSEN1 protein mutant form promotes the reaction [sulindac sulfide affects the cleavage of APP protein]affects cleavage|increases reaction 12805356
C025462 sulindac sulfide sulindac sulfide affects the cleavage of and affects the localization of APP proteinaffects cleavage|affects localization 18359496
C025462 sulindac sulfide sulindac sulfide affects the cleavage of APP proteinaffects cleavage 15274632
18426795
12637581
11700559
12805356
12777371
C025462 sulindac sulfide sulindac sulfide affects the reaction [PSEN1 protein affects the cleavage of APP protein]affects cleavage|affects reaction 17962197
C025462 sulindac sulfide [sulindac sulfide results in decreased activity of PSEN1 protein] which affects the cleavage of APP proteinaffects cleavage|decreases activity 17573346
C025462 sulindac sulfide sulindac sulfide affects the cleavage of APP proteinaffects cleavage 14690522
C025462 sulindac sulfide sulindac sulfide inhibits the reaction [APP protein results in increased uptake of Calcium]decreases reaction|increases uptake 18648507
D013481 Superoxides resveratrol inhibits the reaction [APP protein results in increased abundance of Superoxides]decreases reaction|increases abundance 16212921
D013501 Surface-Active Agents Surface-Active Agents promotes the reaction [APP protein binds to APP protein binds to APP protein]affects binding|increases reaction 16956295
C446685 systhane systhane results in increased expression of APP mRNAincreases expression 19423681
D014284 Triiodothyronine Tretinoin promotes the reaction [Triiodothyronine results in decreased secretion of APP protein]decreases secretion|increases reaction 17199430
D014284 Triiodothyronine Triiodothyronine results in decreased expression of APP mRNAdecreases expression 17199430
D014284 Triiodothyronine Triiodothyronine results in decreased expression of APP proteindecreases expression 17199430
D013974 Thyroxine Thyroxine results in decreased cleavage of APP proteindecreases cleavage 17199430
D013974 Thyroxine Thyroxine results in decreased expression of APP mRNAdecreases expression 17199430
D013974 Thyroxine Thyroxine results in decreased expression of APP proteindecreases expression 17199430
D013629 Tamoxifen Tamoxifen affects the expression of APP mRNAaffects expression 17555576
D013629 Tamoxifen Tamoxifen results in decreased expression of APP mRNAdecreases expression 19400957
D013629 Tamoxifen Tamoxifen results in decreased expression of APP mRNAdecreases expression 19400957
C004648 testosterone enanthate testosterone enanthate affects the expression of APP mRNAaffects expression 17440010
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of APP mRNAaffects cotreatment|decreases expression 17942748
C009462 thioflavin T thioflavin T binds to APP proteinaffects binding 16386399
15134570
C052083 tiliroside tiliroside inhibits the reaction [APP protein binds to APP protein]affects binding|decreases reaction 17323972
D014212 Tretinoin [BDNF protein co-treated with Tretinoin] results in increased expression of APP proteinaffects cotreatment|increases expression 16150056
D014212 Tretinoin Tretinoin promotes the reaction [Triiodothyronine results in decreased secretion of APP protein]decreases secretion|increases reaction 17199430
D014212 Tretinoin Tretinoin results in increased expression of APP proteinincreases expression 16150056
D014212 Tretinoin Tretinoin results in increased metabolism of and results in increased secretion of APP proteinincreases metabolic processing|increases secretion 16150056
D014212 Tretinoin Tretinoin inhibits the reaction [Vitamin A affects the expression of APP mRNA]affects expression|decreases reaction 16530976
C032910 triadimefon triadimefon results in increased expression of APP mRNAincreases expression 19423681
D014236 Trichlorfon Trichlorfon results in increased secretion of APP protein alternative formincreases secretion 11526466
D014236 Trichlorfon Trichlorfon affects the cleavage of APP proteinaffects cleavage 11099780
11822883
D014236 Trichlorfon Trichlorfon affects the metabolism of APP proteinaffects metabolic processing 10773217
C058508 tris(acetylacetonate) aluminum(III) tris(acetylacetonate) aluminum(III) promotes the reaction [Phosphates affects the folding of APP protein]affects folding|increases reaction 10400240
C058508 tris(acetylacetonate) aluminum(III) tris(acetylacetonate) aluminum(III) promotes the reaction [Phosphates promotes the reaction [APP protein binds to APP protein]]affects binding|increases reaction 10400240
D014501 Uranium Uranium affects the expression of APP mRNAaffects expression 15672453
C005460 uranyl acetate uranyl acetate affects the expression of APP mRNAaffects expression 15672453
C025643 vinclozolin vinclozolin affects the expression of APP mRNAaffects expression 19015723
D014801 Vitamin A Tretinoin inhibits the reaction [Vitamin A affects the expression of APP mRNA]affects expression|decreases reaction 16530976
D014801 Vitamin A Vitamin A affects the expression of APP mRNAaffects expression 16530976
D014810 Vitamin E Vitamin E results in decreased expression of APP mRNAdecreases expression 19244175
D014810 Vitamin E Vitamin E inhibits the reaction [Aluminum results in increased cleavage of APP protein]decreases reaction|increases cleavage 12039845
C108830 Y 27632 ROCK1 protein affects the reaction [Y 27632 affects the cleavage of APP protein]affects cleavage|affects reaction 14615541
C108830 Y 27632 Y 27632 affects the cleavage of APP proteinaffects cleavage 14615541
C496381 YU101 YU101 inhibits the reaction [resveratrol results in decreased secretion of APP protein]decreases reaction|decreases secretion 16162502
D015032 Zinc Clioquinol inhibits the reaction [Zinc results in increased secretion of APP protein alternative form]decreases reaction|increases secretion 16648635
D015032 Zinc Zinc binds to and affects the folding of APP proteinaffects binding|affects folding 16325427
D015032 Zinc Zinc binds to APP proteinaffects binding 17119284
16266835
D015032 Zinc Zinc binds to APP protein alternative formaffects binding 15699049
D015032 Zinc Zinc results in increased secretion of APP protein alternative formincreases secretion 16648635
D015032 Zinc [Zinc promotes the reaction [APP protein binds to APP protein]] which affects the transport of Potassiumaffects binding|affects transport|increases reaction 16674922
D015032 Zinc Zinc affects the folding of and affects the localization of APP proteinaffects folding|affects localization 16689927
D015032 Zinc Zinc promotes the reaction [APP protein binds to APP protein]affects binding|increases reaction 16674922
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Sulindac 9.2414745880
MESH:D000008 Abdominal Neoplasms Tamoxifen 9.2414745880
MESH:D000014 Abnormalities, Drug-Induced 2-ethoxyethanol 8.186499812 6499820 7151721 6499823 6499796
MESH:D000014 Abnormalities, Drug-Induced methyl cellosolve 8.183652986 6499812 6474471
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 8.1814514962 15322242 11752688
MESH:D000015 Abnormalities, Multiple Vitamin A 3.8310992263
MESH:D000138 Acidosis Ammonium Chloride 2.4518287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 2.8017505938
MESH:D000169 Acrodermatitis Zinc 4.2817190629 17202136 16889938
MESH:D058186 Acute Kidney Injury Ibuprofen 12.306375363
MESH:D058186 Acute Kidney Injury resveratrol 12.3016538975
MESH:D058186 Acute Kidney Injury Sulindac 12.307897758
MESH:D058186 Acute Kidney Injury Superoxides 12.3018460982
MESH:D055371 Acute Lung Injury Acrolein 17.5721297076 20525806
MESH:D055371 Acute Lung Injury Lipopolysaccharides 17.5718653653 11850527
MESH:D055371 Acute Lung Injury Nickel 17.5716166738
MESH:D055371 Acute Lung Injury Particulate Matter 17.5712396868
MESH:D055371 Acute Lung Injury pirinixic acid 17.5718653653
MESH:D000230 Adenocarcinoma arsenic trioxide 10.8219825857 11798837
MESH:D000230 Adenocarcinoma Doxorubicin 10.8217418594
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 10.8214692618
MESH:D000230 Adenocarcinoma Ibuprofen 10.8210697514
MESH:D000230 Adenocarcinoma Indomethacin 10.8216537180
MESH:D000230 Adenocarcinoma Sulindac 10.8211910360
MESH:D000236 Adenoma Diethylnitrosamine 12.7210737359 6695378
MESH:D000236 Adenoma Indomethacin 12.7211497255
MESH:D000236 Adenoma Melatonin 12.7217195641
MESH:D000236 Adenoma resveratrol 12.7215688382
MESH:D000236 Adenoma Sulindac 12.7210223192
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 10.8617620307 19061943 19052882 16434500 17162532 18056438
MESH:D018248 Adenoma, Liver Cell pirinixic acid 10.8616434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 10.8616835633
MESH:D011125 Adenomatous Polyposis Coli celecoxib 14.9119003578 16215675
MESH:D011125 Adenomatous Polyposis Coli Dinoprostone 14.9117942926
MESH:D011125 Adenomatous Polyposis Coli Flurbiprofen 14.9110680582
MESH:D011125 Adenomatous Polyposis Coli Sulindac 14.9116460482 19003578 11874996 11535846 12394442 17611924 15623613
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 3.5615276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 3.7616712894 17306315
MESH:D000382 Agricultural Workers' Diseases Dichlorvos 3.8816611668 17119214 12661182
MESH:D000419 Albuminuria Doxorubicin 3.4621441931
MESH:D000437 Alcoholism Mecamylamine 4.7120201817
MESH:D019973 Alcohol-Related Disorders Curcumin 3.9417887948
MESH:D000505 Alopecia Tretinoin 2.6715955085
MESH:D019896 alpha 1-Antitrypsin Deficiency Iron 4.5316640825
MESH:D016301 Alveolar Bone Loss Indomethacin 4.2317225004
MESH:D000544 Alzheimer Disease marker/mechanism 15591071 15590663 16266835 16492752 16969627 20157255 16204253 16325427 17239395 17430250 18583042
MESH:D000544 Alzheimer Disease 24-hydroxycholesterol 77.2714523054
MESH:D000544 Alzheimer Disease 27-hydroxycholesterol 77.2714523054 20157255
MESH:D000544 Alzheimer Disease Acrolein 77.2717570602 15207723 14715435
MESH:D000544 Alzheimer Disease Aluminum 77.2710721010 17662457
MESH:D000544 Alzheimer Disease Amphotericin B 77.2712755626
MESH:D000544 Alzheimer Disease Cholesterol, Dietary 77.2720157255
MESH:D000544 Alzheimer Disease Clioquinol 77.2717308104 16648635
MESH:D000544 Alzheimer Disease Copper 77.2716962711 16325427 16886094 17119284 16866297 16410023
MESH:D000544 Alzheimer Disease Curcumin 77.2715590663
MESH:D000544 Alzheimer Disease DP 155 77.2717627676
MESH:D000544 Alzheimer Disease Heparin, Low-Molecular-Weight 77.279453569
MESH:D000544 Alzheimer Disease Ibuprofen 77.2718351690
MESH:D000544 Alzheimer Disease icariin 77.2719782061 19858766
MESH:D000544 Alzheimer Disease Indomethacin 77.2715579461 17627676
MESH:D000544 Alzheimer Disease Iron 77.2716563566 16640825
MESH:D000544 Alzheimer Disease Lithium 77.2719621015
MESH:D000544 Alzheimer Disease Nicotine 77.2716627626
MESH:D000544 Alzheimer Disease Nitric Oxide 77.2717556102
MESH:D000544 Alzheimer Disease Ozone 77.2715513908
MESH:D000544 Alzheimer Disease Particulate Matter 77.2715513908
MESH:D000544 Alzheimer Disease Plant Extracts 77.2716962711
MESH:D000544 Alzheimer Disease resveratrol 77.2716183991 16162502
MESH:D000544 Alzheimer Disease rosiglitazone 77.2719621015
MESH:D000544 Alzheimer Disease sulindac sulfide 77.2718759972
MESH:D000544 Alzheimer Disease Trichlorfon 77.2711419566
MESH:D000544 Alzheimer Disease Zinc 77.2716325427 16410023 17119284 16580781
MESH:D000690 Amyotrophic Lateral Sclerosis 4-hydroxy-2-nonenal 5.7810965797
MESH:D000690 Amyotrophic Lateral Sclerosis Copper 5.7810694572
MESH:D000707 Anaphylaxis Ibuprofen 4.159532969
MESH:D000740 Anemia Iron 9.1916566752 16434484
MESH:D000740 Anemia Tetrachlorodibenzodioxin 9.1911748828
MESH:D000740 Anemia Vitamin A 9.1916960172
MESH:D000741 Anemia, Aplastic Benzene 3.4314761424 11369114 17661222
MESH:D000743 Anemia, Hemolytic Quercetin 3.2117084956
MESH:D018798 Anemia, Iron-Deficiency Copper 11.0616614410
MESH:D018798 Anemia, Iron-Deficiency Iron 11.0617375513 17147795 17163184 16569441 17162259
MESH:D018798 Anemia, Iron-Deficiency Vitamin A 11.0616960172
MESH:D000748 Anemia, Macrocytic methyl cellosolve 5.203699323
MESH:D000755 Anemia, Sickle Cell Zinc 3.8216916123
MESH:D000756 Anemia, Sideroblastic Iron 12.0316910769
MESH:D000756 Anemia, Sideroblastic Manganese 12.0316910769
MESH:D000756 Anemia, Sideroblastic Superoxides 12.0316910769
MESH:D001008 Anxiety Disorders Pentobarbital 6.1211141031 18313124
MESH:D001008 Anxiety Disorders vinclozolin 6.1219015723
MESH:D001014 Aortic Aneurysm Dinoprostone 8.6210231640
MESH:D001014 Aortic Aneurysm Indomethacin 8.6210231640
MESH:D017544 Aortic Aneurysm, Abdominal Dinoprostone 8.6310388637
MESH:D017544 Aortic Aneurysm, Abdominal Indomethacin 8.6310388637
MESH:D001145 Arrhythmias, Cardiac Iron 3.3816604332
MESH:D001161 Arteriosclerosis Acrolein 11.0515014928
MESH:D001161 Arteriosclerosis Cholesterol, Dietary 11.0515552841
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 11.0511256880
MESH:D018771 Arthralgia Indomethacin 4.032160914
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 10.8215885639
MESH:D001169 Arthritis, Experimental Plant Extracts 10.8214686799
MESH:D001169 Arthritis, Experimental resveratrol 10.8217115116
MESH:D001169 Arthritis, Experimental Tretinoin 10.8216412693
MESH:D001172 Arthritis, Rheumatoid Curcumin 6.7616807698
MESH:D001172 Arthritis, Rheumatoid Indomethacin 6.7611248219
MESH:D001172 Arthritis, Rheumatoid Ozone 6.7615570426
MESH:D001172 Arthritis, Rheumatoid Tretinoin 6.7616292516
MESH:D053627 Asthenozoospermia 2-ethoxyethanol 8.8910689203 6499807 6499823
MESH:D053627 Asthenozoospermia methyl cellosolve 8.893987992
MESH:D001249 Asthma Mustard Gas 9.1810378619
MESH:D001249 Asthma Ozone 9.1817854713 16373670
MESH:D001249 Asthma Tretinoin 9.1816456186
MESH:D001249 Asthma Vitamin A 9.1816732791
MESH:D001249 Asthma Zinc 9.1817085522
MESH:D001259 Ataxia 1-Butanol 8.377820390
MESH:D001259 Ataxia 2-ethoxyethanol 8.377151721
MESH:D001260 Ataxia Telangiectasia Iron 9.3915336622
MESH:D001260 Ataxia Telangiectasia Quercetin 9.3915336622
MESH:D050197 Atherosclerosis 27-hydroxycholesterol 18.8311166758 9059518
MESH:D050197 Atherosclerosis Acrolein 18.8316037261 17363696 16126721
MESH:D050197 Atherosclerosis Cadmium 18.8315687053
MESH:D050197 Atherosclerosis Cholesterol 18.8316632123
MESH:D050197 Atherosclerosis Curcumin 18.8318704882
MESH:D050197 Atherosclerosis Iron 18.8316632123 16640825
MESH:D050197 Atherosclerosis resveratrol 18.8316873680 17967414
MESH:D001284 Atrophy 2-ethoxyethanol 7.8415850284 6499799
MESH:D001284 Atrophy methyl cellosolve 7.846705890 2626667 3699323
MESH:D001321 Autistic Disorder Homocysteine 2.4316297937 20468076
MESH:D001321 Autistic Disorder Iron 2.4317352947
MESH:D001321 Autistic Disorder Melatonin 2.4316919138 16897403
MESH:D001321 Autistic Disorder pioglitazone 2.4317207275
MESH:D001321 Autistic Disorder Serotonin 2.438570775 18405062 19221690 15132762 17157402 18062943 18361446
MESH:D001327 Autoimmune Diseases Curcumin 7.2319761891
MESH:D001327 Autoimmune Diseases Quercetin 7.2319761891
MESH:D053713 Azoospermia 2-ethoxyethanol 4.486499807 6492198
MESH:D001424 Bacterial Infections Iron 4.0716640825
MESH:D001471 Barrett Esophagus Tretinoin 3.3216935849
MESH:D001477 Bartter Syndrome Dinoprostone 9.0515976003
MESH:D001477 Bartter Syndrome Indomethacin 9.0510684365
MESH:D001480 Basal Ganglia Diseases Dichlorvos 4.8615303389
MESH:D001714 Bipolar Disorder Lithium 3.6119153942 20046352 17594078 20338123
MESH:D001724 Birth Weight 2-ethoxyethanol 5.372884743 6499823
MESH:D001768 Blister Mustard Gas 4.0319167455
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 18.0416206674
MESH:D001778 Blood Coagulation Disorders pirinixic acid 18.0419483382
MESH:D001778 Blood Coagulation Disorders Propylthiouracil 18.0419483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 18.0412125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 18.0416206674 16197459
MESH:D001836 Body Weight Changes 2-ethoxyethanol 8.257151721 6499796
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 8.2515340226
MESH:D001847 Bone Diseases icariin 5.2818295595
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 1.9315746008
MESH:D001851 Bone Diseases, Metabolic Ginkgo biloba extract 761 5.2219356626
MESH:D001855 Bone Marrow Diseases Benzene 4.0916183116
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 3.5614601052
MESH:D001913 Bowen's Disease Sulindac 4.2111207687
MESH:D001919 Bradycardia Serotonin 4.368112388
MESH:D001929 Brain Edema Indomethacin 3.8911481608
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 4.1917868700
MESH:D001930 Brain Injuries Nitroprusside 12.3114637104
MESH:D001930 Brain Injuries Progesterone 12.3115845082 15665606 15380490
MESH:D001930 Brain Injuries Zinc 12.3117109824
MESH:D002545 Brain Ischemia Curcumin 30.7216770732
MESH:D002545 Brain Ischemia Ibuprofen 30.7215837124
MESH:D002545 Brain Ischemia icariin 30.7219303870
MESH:D002545 Brain Ischemia Indomethacin 30.7212524144
MESH:D002545 Brain Ischemia Plant Extracts 30.7216041641
MESH:D002545 Brain Ischemia resveratrol 30.7217600658
MESH:D002545 Brain Ischemia scutellarin 30.7216297343
MESH:D001932 Brain Neoplasms Copper 9.0217079463
MESH:D001932 Brain Neoplasms Curcumin 9.0217596214
MESH:D001932 Brain Neoplasms Doxorubicin 9.0217150277
MESH:D001943 Breast Neoplasms Benzene 13.3011921183 17162533
MESH:D001943 Breast Neoplasms bexarotene 13.3016344269 16818667
MESH:D001943 Breast Neoplasms Copper 13.3015986119 17079463
MESH:D001943 Breast Neoplasms Curcumin 13.3016243823 18593918 18462866 19250217
MESH:D001943 Breast Neoplasms Deoxyglucose 13.3018985042
MESH:D001943 Breast Neoplasms Diethylnitrosamine 13.3017474063
MESH:D001943 Breast Neoplasms Doxorubicin 13.3018382427 15634643 16826403 15994142 15692762 15939500 17983394 16935488 16096432 16595493 16115903 16322301 18234424 15567936 15993339 17426702 17369602 15136595 11325840 16264153 18628466 19526202 15668708 18695136
MESH:D001943 Breast Neoplasms Indomethacin 13.3017401462
MESH:D001943 Breast Neoplasms kaempferol 13.3016756079
MESH:D001943 Breast Neoplasms Nickel 13.3015986119
MESH:D001943 Breast Neoplasms Nitric Oxide 13.3015631943
MESH:D001943 Breast Neoplasms Progesterone 13.3016175315 15562024 17614352
MESH:D001943 Breast Neoplasms Quercetin 13.3018628248
MESH:D001943 Breast Neoplasms resveratrol 13.3017651959 16393696 17534123
MESH:D001943 Breast Neoplasms Sulindac 13.3016642371
MESH:D001943 Breast Neoplasms Tamoxifen 13.3017893378 11161223 17261762 20005174 21152245 19289846 18815881 17242785 19011961 20135344 19189212 18425577 19189210 18984771 19221464 18855134 19115204 19142967 15668708 16202921 19288272 18351453 18629630 16873071 20859285 19487384 19155303 17049068 20390343 19244106 19200415 16818667 15565566 17440819 19084267 16273361 20544844 18821012 18997820 20065188 19410462 19059307 21138602 19103187 19066611
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 13.3020435547
MESH:D001943 Breast Neoplasms Tretinoin 13.3016873071 16443354 16166294
MESH:D016535 Bronchial Hyperreactivity Ozone 2.7418417511 15516495 14754758 18315731 16777450 19059883 17626835
MESH:D001989 Bronchiolitis Obliterans Mustard Gas 4.0315286001
MESH:D029481 Bronchitis, Chronic Mustard Gas 3.8410378619 17687719
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 9.3016813970
MESH:D001997 Bronchopulmonary Dysplasia Vitamin A 9.3017426644 17377406
MESH:D002051 Burkitt Lymphoma arsenic trioxide 3.2711589617
MESH:D002056 Burns Indomethacin 3.6110459503
MESH:D002057 Burns, Chemical Plant Extracts 4.209625245
MESH:D002100 Cachexia Ibuprofen 14.7015141370
MESH:D002100 Cachexia Indomethacin 14.7015625704 16537180 15141370 11239499
MESH:D002100 Cachexia Ozone 14.7016183385
MESH:D002105 Cadmium Poisoning Quercetin 4.4016962696
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 10.6916124888 10355542 16011737 15700767 16097048 15721981 18705752 3786805 16192424 16227642 16050911 15673190
MESH:D002252 Carbon Tetrachloride Poisoning Melatonin 10.6915700767
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 10.6916050911
MESH:D002276 Carcinoid Tumor Doxorubicin 3.6716051944
MESH:D002277 Carcinoma Curcumin 5.1418593918
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 5.1416835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 3.4019066611
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.0116168501
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 27.4216705839
MESH:D006528 Carcinoma, Hepatocellular anthra(1,9-cd)pyrazol-6(2H)-one 27.4219418558
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 27.4214691202 15553829 11135700 16217749 15073043
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 27.4218788625
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 27.4219383236 20007298 18971187 17428255 20101231 19335982 16540662 18785209 16328049 19394651 18494052 16807293 18691550 20524982 11831363 19519916 16502159 3581430 17162532 17761372 20214788 20935162 19107877 18506893 20512989 20084675 18056438 16288022 21159647 17173139 16779866 3084413 16935385 10672840 19208518 20514400 16830150 17055752 18978308 18210153 16569478 19171122 10737359 17138121 20727157 19539802 19418558 17978847 16681979 19701751 20432363 18788625 16698587 19052882 18665156 19919837 19822196 16878318 18393292
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 27.4218059187 17876044 16023760 16234567
MESH:D006528 Carcinoma, Hepatocellular Indomethacin 27.4216391822
MESH:D006528 Carcinoma, Hepatocellular morin 27.4219539802
MESH:D006528 Carcinoma, Hepatocellular Plant Extracts 27.4218834353
MESH:D006528 Carcinoma, Hepatocellular Quercetin 27.4212508355 19519916
MESH:D006528 Carcinoma, Hepatocellular resveratrol 27.4219321006 16227395
MESH:D006528 Carcinoma, Hepatocellular SC 560 27.4216391822
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 27.4216507464 17306315 15276417
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 27.4216924424
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 27.421917145
MESH:D018827 Carcinoma, Lewis Lung Indomethacin 7.7211053908
MESH:D018827 Carcinoma, Lewis Lung resveratrol 7.7216675471
MESH:D018276 Carcinoma, Medullary Indomethacin 4.2218791128 14736730 11352223
MESH:D002289 Carcinoma, Non-Small-Cell Lung bexarotene 5.7616247446
MESH:D002289 Carcinoma, Non-Small-Cell Lung Curcumin 5.7618414057
MESH:D002289 Carcinoma, Non-Small-Cell Lung sulindac sulfide 5.7612391285
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 3.8517234771
MESH:D002291 Carcinoma, Papillary arsenic trioxide 3.7319014326
MESH:D002292 Carcinoma, Renal Cell celecoxib 6.9716369983
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 6.971485588 16201981
MESH:D002292 Carcinoma, Renal Cell Indomethacin 6.9717341418
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.1012490120
MESH:D002294 Carcinoma, Squamous Cell Curcumin 13.8818462866
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 13.886189445
MESH:D002294 Carcinoma, Squamous Cell Indomethacin 13.8812636206 15482327
MESH:D002294 Carcinoma, Squamous Cell resveratrol 13.8816227395
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 13.8818572023
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 13.8816096774 16051514
MESH:D002294 Carcinoma, Squamous Cell Zinc 13.8816543248
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 2.6117572228
MESH:D006332 Cardiomegaly Copper 13.3417327471
MESH:D006332 Cardiomegaly Plant Extracts 13.3417645561
MESH:D006332 Cardiomegaly Quercetin 13.3419794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 13.3418670907 18850075 16120746
MESH:D006332 Cardiomegaly Thyroxine 13.3418093424
MESH:D009202 Cardiomyopathies Doxorubicin 5.3416364871 17308081 15505089 16455267 16731534 17519947 16109756 16242529 16651473 15476868 16269455 17007740 15792986 17924179 15811867 16612575 17329180 17974986 18627295 17382496 17928571 17131338 16278810 16952015 17351982
MESH:D009202 Cardiomyopathies Iron 5.3416640825
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 4.2816243910 17334414
MESH:D002311 Cardiomyopathy, Dilated Iron 4.2816604332
MESH:D002318 Cardiovascular Diseases Hydrogen Peroxide 13.5816936243
MESH:D002318 Cardiovascular Diseases kaempferol 13.5816756079
MESH:D002318 Cardiovascular Diseases Particulate Matter 13.5812396868
MESH:D002318 Cardiovascular Diseases resveratrol 13.5815458977
MESH:D002318 Cardiovascular Diseases Zinc 13.5816936243
MESH:D002386 Cataract Adenosine Triphosphate 5.3215003327
MESH:D002386 Cataract Tretinoin 5.3217460283
MESH:D002418 Cattle Diseases Dichlorvos 8.4414651886
MESH:D002418 Cattle Diseases Trichlorfon 8.4414651886
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 11.996135515
MESH:D002471 Cell Transformation, Neoplastic Cadmium 11.9917332340
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 11.9917174075 2727394 7505956 21159647
MESH:D002471 Cell Transformation, Neoplastic Dinoprostone 11.9916192471
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 11.9920056578 19524636
MESH:D002493 Central Nervous System Diseases Dichlorvos 4.6512670839
MESH:D016657 Cerebral Amyloid Angiopathy marker/mechanism
OMIM:605714 CEREBRAL AMYLOID ANGIOPATHY, APP-RELATED marker/mechanism
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 3.4716129372
MESH:D002659 Child Development Disorders, Pervasive Serotonin 3.6121254450
MESH:D015362 Child Nutrition Disorders Vitamin A 4.3416153327
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 6.0319052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 6.0316835633
MESH:D002764 Cholecystitis 2-ethoxyethanol 16.176499794
MESH:D002764 Cholecystitis Indomethacin 16.1711181007
MESH:D002764 Cholecystitis methyl cellosolve 16.176499794
MESH:D002779 Cholestasis Ethinyl Estradiol 11.8917681005 17333356 16919318 17110522 16105132 15861022 11677210
MESH:D002779 Cholestasis Nitric Oxide 11.8916919318
MESH:D002779 Cholestasis pirinixic acid 11.8919176532
MESH:D002779 Cholestasis Vitamin A 11.8916175620
MESH:D002822 Choriocarcinoma Tretinoin 4.0116461808
MESH:D021081 Chronobiology Disorders Serotonin 5.5517157402
MESH:D016770 Ciliophora Infections Quinine 4.6612113305
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 8.7712621046 15668235 15340226 16354765 8697196
MESH:D002972 Cleft Palate Tretinoin 8.779407595
MESH:D002972 Cleft Palate triadimefon 8.7716781842
MESH:D002972 Cleft Palate Vitamin A 8.7716054864
MESH:D003092 Colitis Curcumin 13.9718200517 16782535 16804969
MESH:D003092 Colitis resveratrol 13.9716474422
MESH:D003092 Colitis Selenium 13.9717936198
MESH:D003092 Colitis Tretinoin 13.9717035595
MESH:D003103 Coloboma Curcumin 3.5118809619
MESH:D003110 Colonic Neoplasms celecoxib 13.4416004971
MESH:D003110 Colonic Neoplasms Curcumin 13.4419359593 16340194
MESH:D003110 Colonic Neoplasms Indomethacin 13.4415637740 15786552 11260862 15936596 15963497 15625704
MESH:D003110 Colonic Neoplasms Iron 13.4416640825
MESH:D003110 Colonic Neoplasms Quercetin 13.4419440933 19056647 11134977 17191121 17148506 16640504 15741050
MESH:D003110 Colonic Neoplasms resveratrol 13.4416338953
MESH:D003110 Colonic Neoplasms Sulindac 13.4412458338 12902858
MESH:D003110 Colonic Neoplasms Vitamin A 13.4417219422 16267017
MESH:D015179 Colorectal Neoplasms Acrolein 10.1417597105
MESH:D015179 Colorectal Neoplasms arsenic trioxide 10.1420501625
MESH:D015179 Colorectal Neoplasms celecoxib 10.1418349538 11197048
MESH:D015179 Colorectal Neoplasms Doxorubicin 10.1418802399 18259882
MESH:D015179 Colorectal Neoplasms Indomethacin 10.1412606626 17054584 11197048 18059344
MESH:D015179 Colorectal Neoplasms meloxicam 10.1411197048
MESH:D015179 Colorectal Neoplasms Quercetin 10.1418852136 18095365
MESH:D015179 Colorectal Neoplasms resveratrol 10.1416550006
MESH:D015179 Colorectal Neoplasms Sulindac 10.1411197048 10666051 11076880 18059344
MESH:D003128 Coma Dichlorvos 9.5815303389
MESH:D003128 Coma Ginkgo biloba extract 761 9.5810836866
MESH:D000013 Congenital Abnormalities methyl cellosolve 6.1412530607 6499821
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 6.1417141729 14669216
MESH:D016510 Corneal Neovascularization Curcumin 3.7918497527
MESH:D003324 Coronary Artery Disease Homocysteine 3.2016379339
MESH:D003327 Coronary Disease resveratrol 2.9216507316
MESH:D023903 Coronary Restenosis arsenic trioxide 3.1112609071
MESH:D018352 Coronavirus Infections Indomethacin 4.5717302372
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 13.3610525206
MESH:D019465 Craniofacial Abnormalities Benzene 13.3615643154
MESH:D019465 Craniofacial Abnormalities Lead 13.3619769572
MESH:D019465 Craniofacial Abnormalities Reactive Oxygen Species 13.3615736158
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 13.3620055451 15322242 10048152
MESH:D019465 Craniofacial Abnormalities Tretinoin 13.3616925845 17551590 9211117 8800419 9224671 14991402 9142499 10589399 9125849 9664655
MESH:D019465 Craniofacial Abnormalities triadimefon 13.3616875885 15834900
MESH:D019465 Craniofacial Abnormalities Vitamin A 13.3610992263
MESH:D019465 Craniofacial Abnormalities Vitamin E 13.3619769572
MESH:D019465 Craniofacial Abnormalities Zinc 13.3619302082
MESH:D003456 Cryptorchidism vinclozolin 3.2614966744
MESH:D003490 Cyanosis 2,6-dinitrotoluene 2.9218551238
MESH:D003550 Cystic Fibrosis pioglitazone 3.9419747007
MESH:D003556 Cystitis Acrolein 4.2612161096
MESH:D007644 Darier Disease Lithium 4.7920338123
MESH:D003643 Death 2-ethoxyethanol 10.226499796
MESH:D003643 Death Pentylenetetrazole 10.226431079
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.0415213294
MESH:D003704 Dementia Lead 4.2216140633
MESH:D015140 Dementia, Vascular Nitric Oxide 4.8317556102
MESH:D003711 Demyelinating Diseases Tamoxifen 3.2619031437
MESH:D003715 Dengue 24-hydroxycholesterol 12.8019427377
MESH:D003715 Dengue 27-hydroxycholesterol 12.8019427377
MESH:D003715 Dengue cholest-5-en-3 beta,7 alpha-diol 12.8019427377
MESH:D003872 Dermatitis Benzene 3.6715902427
MESH:D017449 Dermatitis, Allergic Contact Nickel 2.9917100760 17244072 19470301
MESH:D003876 Dermatitis, Atopic pirinixic acid 1.7618249437
MESH:D003877 Dermatitis, Contact Nickel 3.602952479
MESH:D018500 Diabetes Insipidus, Nephrogenic Lithium 4.6419244398
MESH:D003920 Diabetes Mellitus Iron 9.9116640825 16604332
MESH:D003920 Diabetes Mellitus rosiglitazone 9.9117446233
MESH:D003920 Diabetes Mellitus Zinc 9.9116479319
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 5.3619496084
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 5.3616873680
MESH:D003922 Diabetes Mellitus, Type 1 Iron 4.3016506275
MESH:D003922 Diabetes Mellitus, Type 1 Vitamin A 4.3016506275
MESH:D003924 Diabetes Mellitus, Type 2 astaxanthine 13.6416964424
MESH:D003924 Diabetes Mellitus, Type 2 Curcumin 13.6418403477
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 13.6420387270
MESH:D003924 Diabetes Mellitus, Type 2 Iron 13.6416506275
MESH:D003924 Diabetes Mellitus, Type 2 pioglitazone 13.6416023994 12642470
MESH:D003924 Diabetes Mellitus, Type 2 rosiglitazone 13.6412642470
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 13.6417107852
MESH:D003928 Diabetic Nephropathies Curcumin 13.4318204486
MESH:D003928 Diabetic Nephropathies Plant Extracts 13.4319706694
MESH:D003928 Diabetic Nephropathies resveratrol 13.4316286809
MESH:D003928 Diabetic Nephropathies Tamoxifen 13.4319279558
MESH:D003929 Diabetic Neuropathies Progesterone 3.3917187935
MESH:D003930 Diabetic Retinopathy Sulindac 4.1012861449 17621415
MESH:D003967 Diarrhea Dinoprostone 7.6010446763 7237001 11488427
MESH:D003967 Diarrhea Indomethacin 7.607907874 7237001
MESH:D003967 Diarrhea Serotonin 7.608112388 11488427 10446763
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 12.8621346803 18551238
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 12.8611566570 16177239 19336974 19085960 6884620 15968718 7179309 7120509 2869522 15998439 15027814 17522070 10092053 3732212 16227642 9327722 10915739 4309450 21278145 7440962 3786805 6623471
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 12.8619107877
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 12.8617416283
MESH:D056486 Drug-Induced Liver Injury fumonisin B1 12.8616221962
MESH:D056486 Drug-Induced Liver Injury scutellarin 12.8615131321
MESH:D056486 Drug-Induced Liver Injury Selenium 12.8615131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 12.8620420201
MESH:D004362 Drug Toxicity Doxorubicin 5.0818602426
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 5.0811462148
MESH:D015352 Dry Eye Syndromes Vitamin A 4.6816146918
MESH:D004374 Ductus Arteriosus, Patent Ibuprofen 9.5116133044 18446180 18450898
MESH:D004374 Ductus Arteriosus, Patent Indomethacin 9.5117190690 18446180 16133044 18043480 16326151 12774134
MESH:D004381 Duodenal Ulcer Curcumin 5.8917351913
MESH:D004381 Duodenal Ulcer Indomethacin 5.8911595431 17329845 17202747 17351913 17045617 17151854 11535926 11595415 16699067 10671773 11991626
MESH:D050171 Dyslipidemias Fenofibrate 3.5316707586
MESH:D020821 Dystonic Disorders Nicotine 4.8017881519
MESH:C538011 Eales disease Vitamin A 9.349068938
MESH:C538011 Eales disease Vitamin E 9.349068938
MESH:D004480 Ectromelia Vitamin A 4.6816054864
MESH:D004487 Edema Indomethacin 24.247990266 7907874 8985016 16100529 10653021 19703484 8273558
MESH:D004487 Edema Mustard Gas 24.249260866 11402378 11428631 11428647
MESH:D004487 Edema pirinixic acid 24.2412083418
MESH:D004487 Edema Plant Extracts 24.2412787963
MESH:D004487 Edema resveratrol 24.248985016
MESH:D004487 Edema rosiglitazone 24.2412083418
MESH:D004487 Edema Serotonin 24.2418841975
MESH:D004487 Edema Staurosporine 24.248273558
MESH:D004487 Edema Tetrachlorodibenzodioxin 24.2411000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 8.1716714409 15322242 18230668
MESH:D004489 Edema, Cardiac Tretinoin 8.1718230668
MESH:D020964 Embryo Loss 2-ethoxyethanol 5.376499796
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental 24-hydroxycholesterol 22.1017410599
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental 27-hydroxycholesterol 22.1017410599
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 22.1012538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 22.1017692515
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 22.1017872969
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 22.1019031437
MESH:D016889 Endometrial Neoplasms Doxorubicin 10.8817359293
MESH:D016889 Endometrial Neoplasms Fenofibrate 10.8816569247
MESH:D016889 Endometrial Neoplasms Tamoxifen 10.8816202921 20544844 17893378 19155303
MESH:D016889 Endometrial Neoplasms Tretinoin 10.8816569247
MESH:D004715 Endometriosis celecoxib 22.7215652904
MESH:D004715 Endometriosis Ibuprofen 22.7215652904
MESH:D004715 Endometriosis Indomethacin 22.7215652904
MESH:D004715 Endometriosis Progesterone 22.7216134523
MESH:D004715 Endometriosis Sulindac 22.7215652904
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 22.729294722 10568697
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 10.2818037988
MESH:D004719 Endomyocardial Fibrosis Plant Extracts 10.2815268973
MESH:D019446 Endotoxemia endotoxin, Escherichia coli 16.0317637181 18509659
MESH:D019446 Endotoxemia Ibuprofen 16.0311545620
MESH:D019446 Endotoxemia Indomethacin 16.0318509659
MESH:D019446 Endotoxemia Lipopolysaccharides 16.0315328337 17637181 15821434
MESH:D004751 Enteritis Indomethacin 3.6116328016 10567023 17763956
MESH:D020345 Enterocolitis, Necrotizing Indomethacin 8.7217980183
MESH:D020345 Enterocolitis, Necrotizing resveratrol 8.7217923197
MESH:D004802 Eosinophilia Indomethacin 2.9911298111
MESH:D004827 Epilepsy Plant Extracts 3.0319439326 19700373
MESH:D004832 Epilepsy, Absence Pentylenetetrazole 4.676426943
MESH:D007172 Erectile Dysfunction icariin 4.3616281085 15329286
MESH:D004890 Erythema Mustard Gas 4.039357497
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 3.9716302075
MESH:D004938 Esophageal Neoplasms arsenic trioxide 6.4812903497
MESH:D004938 Esophageal Neoplasms Indomethacin 6.4811005569
MESH:D004938 Esophageal Neoplasms Sulindac 6.4812235107
MESH:D004938 Esophageal Neoplasms Zinc 6.4816543248
MESH:D020329 Essential Tremor Lead 4.8118007985 14594619
MESH:D017889 Exfoliation Syndrome Homocysteine 4.5816504073
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 5.7711564622
MESH:D005124 Eye Abnormalities Tretinoin 5.7716938888 9664655
MESH:D005234 Fatty Liver arsenic trioxide 34.1915073043
MESH:D005234 Fatty Liver Carbon Tetrachloride 34.1912795759 16045604 15959796 16239168 17595544 19224547 12631006 61145
MESH:D005234 Fatty Liver Curcumin 34.1919297423
MESH:D005234 Fatty Liver Diethylnitrosamine 34.1920387270 21071580
MESH:D005234 Fatty Liver Ethinyl Estradiol 34.1915345470
MESH:D005234 Fatty Liver Iron 34.1916640825
MESH:D005234 Fatty Liver pirinixic acid 34.1920131406 19236843
MESH:D005234 Fatty Liver Plant Extracts 34.1915975614
MESH:D005234 Fatty Liver rosiglitazone 34.1919196556
MESH:D005234 Fatty Liver Tamoxifen 34.1919224547 14986274
MESH:D052776 Female Urogenital Diseases Tamoxifen 2.4316709447
MESH:D005313 Fetal Death 2-ethoxyethanol 7.202884743 7151721 6499823 6499820 7198755
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 7.2011858732
MESH:D005317 Fetal Growth Retardation 2-ethoxyethanol 8.156499796
MESH:D005317 Fetal Growth Retardation Lead 8.1519769572
MESH:D005327 Fetal Resorption 2-ethoxyethanol 14.096499820 6499812
MESH:D005327 Fetal Resorption methyl cellosolve 14.093987992 6474471 6499812 6499821
MESH:D005327 Fetal Resorption Vitamin A 14.0916054864
MESH:D020567 Fetal Weight 2-ethoxyethanol 9.876499820 2884743 7151721
MESH:D020567 Fetal Weight methyl cellosolve 9.876474471 6499812 6499821
MESH:D005334 Fever Dinoprostone 22.3716997862 11852909
MESH:D005334 Fever DP 155 22.3717627676
MESH:D005334 Fever endotoxin, Escherichia coli 22.3716997862
MESH:D005334 Fever Ibuprofen 22.3716997862
MESH:D005334 Fever Indomethacin 22.3711852909 17627676 10431976
MESH:D005334 Fever Lipopolysaccharides 22.3711852909 9205823
MESH:D018221 Fibromatosis, Abdominal Sulindac 9.2314745880
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 9.2314745880
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 13.1119069698
MESH:D018222 Fibromatosis, Aggressive Sulindac 13.1119069698
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 13.1119069698
MESH:D005354 Fibrosarcoma Indomethacin 3.7710962813
MESH:D005355 Fibrosis baicalein 25.0919474275
MESH:D005355 Fibrosis Carbon Tetrachloride 25.0918705752
MESH:D005355 Fibrosis Curcumin 25.0918705752
MESH:D005355 Fibrosis Indomethacin 25.0917994277
MESH:D005355 Fibrosis Quercetin 25.0919474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 25.0920067830
MESH:D005355 Fibrosis Tretinoin 25.0917994277
MESH:D005393 Fish Diseases Quinine 4.6212113305
MESH:D005499 Folliculitis Indomethacin 4.0311298111
MESH:D005532 Foot Deformities, Congenital methyl cellosolve 4.403652986
MESH:D005621 Friedreich Ataxia Iron 4.3216640825 16604332
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.1816904648
MESH:D005756 Gastritis Indomethacin 7.7915046732
MESH:D005756 Gastritis Zinc 7.7917241300
MESH:D005764 Gastroesophageal Reflux Sulindac 3.9311910360
MESH:D005770 Gastrointestinal Neoplasms Curcumin 3.5918462866
MESH:D030342 Genetic Diseases, Inborn vinclozolin 3.8116973722
MESH:D005832 Genital Diseases, Male vinclozolin 4.1616417039
MESH:D005833 Genital Neoplasms, Female sodium arsenite 3.5516452187
MESH:D005901 Glaucoma Homocysteine 4.2316504073
MESH:D005909 Glioblastoma baicalein 20.6319804834
MESH:D005909 Glioblastoma Curcumin 20.6317596214
MESH:D005909 Glioblastoma Doxorubicin 20.6317150277
MESH:D005909 Glioblastoma Indomethacin 20.6312870263
MESH:D005909 Glioblastoma Manganese 20.6317043766
MESH:D005909 Glioblastoma Quercetin 20.6319804834
MESH:D005909 Glioblastoma Tretinoin 20.6317312396
MESH:D005910 Glioma Indomethacin 4.2416487511 18371953
MESH:D005910 Glioma Quercetin 4.2417643826
MESH:D005923 Glomerulosclerosis, Focal Segmental Indomethacin 7.1311849393
MESH:D005923 Glomerulosclerosis, Focal Segmental pioglitazone 7.1316687628
MESH:D006042 Goiter perchlorate 4.2518801409
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 3.4510696789
MESH:D006073 Gout Indomethacin 4.2211248219
MESH:D006130 Growth Disorders Zinc 3.1317217573
MESH:D006261 Headache Nitric Oxide 4.0511554966 11284996
MESH:D006258 Head and Neck Neoplasms Curcumin 11.4018829502 18462866
MESH:D006258 Head and Neck Neoplasms Doxorubicin 11.4015692506
MESH:D006258 Head and Neck Neoplasms Indomethacin 11.4015482327
MESH:D006258 Head and Neck Neoplasms Tretinoin 11.4016096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.0116084493
MESH:D006330 Heart Defects, Congenital Homocysteine 16.6519638421
MESH:D006330 Heart Defects, Congenital Lithium 16.6519638421
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 16.6510048152 11294989
MESH:D006330 Heart Defects, Congenital Tretinoin 16.659664655 14991402
MESH:D006330 Heart Defects, Congenital Vitamin A 16.6516080930 10992263
MESH:D006330 Heart Defects, Congenital Vitamin E 16.6516080930
MESH:D006331 Heart Diseases Doxorubicin 2.6316244371 16330681 18674790 17888722 16144979 16707910 16879835 12587719 16244372 16495754 18006777 14766674 17875725
MESH:D006333 Heart Failure Doxorubicin 13.5417481944
MESH:D006333 Heart Failure pirinixic acid 13.5420558911
MESH:D006333 Heart Failure Plant Extracts 13.5418097624
MESH:D006333 Heart Failure Selenium 13.5417162251
MESH:D006333 Heart Failure Zinc 13.5417162251
MESH:D006335 Heart Injuries Zinc 4.6217074742
MESH:D006345 Heart Septal Defects, Ventricular methyl cellosolve 4.656499821
MESH:D016481 Helicobacter Infections Zinc 3.4817241300
MESH:D006394 Hemangiosarcoma Doxorubicin 2.8915692506
MESH:D006402 Hematologic Diseases 2-ethoxyethanol 7.8220172899 10514026
MESH:D006402 Hematologic Diseases Benzene 7.8216183116
MESH:D006432 Hemochromatosis Iron 3.5816574947 17255318 16604332 17053826 17236123 16640825
MESH:D006461 Hemolysis 2-ethoxyethanol 8.5719051582 17874071
MESH:D006461 Hemolysis methyl cellosolve 8.5717874071
MESH:D006463 Hemolytic-Uremic Syndrome Lipopolysaccharides 3.3716366002
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.3011000095
MESH:D006486 Hemosiderosis Iron 4.0816604332
MESH:D006501 Hepatic Encephalopathy Indomethacin 3.5315633222
MESH:D006505 Hepatitis Carbon Tetrachloride 2.5419900420 19110552
MESH:D019698 Hepatitis C, Chronic Indomethacin 3.6015135802
MESH:D006521 Hepatitis, Chronic Copper 4.1417338147
MESH:D006525 Hepatitis, Viral, Human Iron 4.3316640825
MESH:D006527 Hepatolenticular Degeneration Copper 12.3317182432 17109627 16607473 17276780 19888908
MESH:D006527 Hepatolenticular Degeneration Iron 12.3317182432
MESH:D006527 Hepatolenticular Degeneration Zinc 12.3317276780
MESH:D006529 Hepatomegaly fumonisin B1 24.2116221962
MESH:D006529 Hepatomegaly Iron 24.2116890145
MESH:D006529 Hepatomegaly pirinixic acid 24.2118467677 19176532 19772884 16221962
MESH:D006529 Hepatomegaly propiconazole 24.2117178688 17178689
MESH:D006529 Hepatomegaly systhane 24.2117178689 17178688
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 24.2115340226 12621046 16120746
MESH:D006529 Hepatomegaly triadimefon 24.2117178689 17178688
MESH:D015417 Hereditary Sensory and Motor Neuropathy Curcumin 3.9317701891
MESH:D006548 Hernia, Diaphragmatic Vitamin A 4.2516877224 16863852 15707848 17436238 16292552 16490937
MESH:D006548 Hernia, Diaphragmatic Vitamin E 4.2516490937 16863852
MESH:D006561 Herpes Simplex Plant Extracts 6.4410715843
MESH:D006561 Herpes Simplex resveratrol 6.4416876885
MESH:D015658 HIV Infections Iron 9.3616597321
MESH:D015658 HIV Infections Nickel 9.3617263646
MESH:D015658 HIV Infections Plant Extracts 9.3612878215
MESH:D015658 HIV Infections Vitamin A 9.3616960176
MESH:D006679 HIV Seropositivity Vitamin A 4.4717209195
MESH:D019247 HIV Wasting Syndrome testosterone enanthate 4.6017440010
MESH:D006689 Hodgkin Disease Doxorubicin 4.3015147373 17606976 18501091
MESH:D006689 Hodgkin Disease sodium arsenite 4.3012676792
MESH:D006734 Horse Diseases Dichlorvos 4.8616402567
MESH:D019584 Hot Flashes Plant Extracts 6.6716566672 14716179 17454163
MESH:D019584 Hot Flashes Vitamin E 6.6714716179
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 2.908697196 15340226 16354765 18606429 16959395
MESH:D006930 Hyperalgesia Dinoprostone 11.0816793879
MESH:D006930 Hyperalgesia Indomethacin 11.0812727271
MESH:D006930 Hyperalgesia rosiglitazone 11.0812083418
MESH:D006930 Hyperalgesia Tretinoin 11.0816870215
MESH:D034321 Hyperamylasemia Indomethacin 4.5717883296
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 3.4116899240
MESH:D006937 Hypercholesterolemia 27-hydroxycholesterol 17.8517873880
MESH:D006937 Hypercholesterolemia Cholesterol 17.8516933029
MESH:D006937 Hypercholesterolemia Cholesterol, Dietary 17.8510876104
MESH:D006937 Hypercholesterolemia Curcumin 17.8518704882
MESH:D006937 Hypercholesterolemia resveratrol 17.8517188708
MESH:D006940 Hyperemia Indomethacin 9.0012524144
MESH:D006940 Hyperemia Nitric Oxide 9.0011156591
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 3.4616778211
MESH:D006941 Hyperesthesia Dichlorvos 5.5512563396
MESH:D006943 Hyperglycemia kaempferol 9.9818262572
MESH:D006943 Hyperglycemia pirinixic acid 9.9820558911
MESH:D006943 Hyperglycemia Quercetin 9.9818262572 11834736
MESH:D020138 Hyperhomocysteinemia Homocysteine 10.1118234410 17292331 17369066
MESH:D020138 Hyperhomocysteinemia Plant Extracts 10.1116484555
MESH:D020138 Hyperhomocysteinemia Superoxides 10.1112615666
MESH:D006949 Hyperlipidemias Indomethacin 9.5917546600
MESH:D006949 Hyperlipidemias Plant Extracts 9.5915975614 15268973
MESH:D006949 Hyperlipidemias resveratrol 9.5916873680
MESH:D006973 Hypertension Benzene 5.1717940673
MESH:D006973 Hypertension Quercetin 5.1718356687
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 5.1718850075 18670907
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 8.1215338365
MESH:D006975 Hypertension, Portal ginkgolide B 8.1216409839
MESH:D006976 Hypertension, Pulmonary Nitric Oxide 3.5415838368
MESH:D006980 Hyperthyroidism Methimazole 4.5314678291
MESH:D006984 Hypertrophy Ibuprofen 3.9416672835
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 3.2917488730
MESH:D006986 Hypervitaminosis A Vitamin A 5.0216054864
MESH:D007006 Hypogonadism Iron 3.5116640825
MESH:D020514 Hypokalemic Periodic Paralysis Potassium 4.7419822448
MESH:D007021 Hypospadias Ethinyl Estradiol 2.7116569931 16945680
MESH:D007022 Hypotension Isoflurane 3.9112967683
MESH:D007037 Hypothyroidism Iron 13.3016640825
MESH:D007037 Hypothyroidism Methimazole 13.3018031379
MESH:D007037 Hypothyroidism Propylthiouracil 13.308137927 18031379
MESH:D007077 Ileal Diseases Indomethacin 3.8918306037 10574470
MESH:D007079 Ileitis Indomethacin 4.2210647630 16133968 10651667
MESH:D007235 Infant, Premature, Diseases Ibuprofen 10.4116133044
MESH:D007235 Infant, Premature, Diseases Indomethacin 10.4116133044
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 7.8415869954
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 7.8417600658
MESH:D007247 Infertility, Female 2-ethoxyethanol 6.906499823
MESH:D007247 Infertility, Female Ethinyl Estradiol 6.9012013081
MESH:D007248 Infertility, Male 2-ethoxyethanol 15.406499823
MESH:D007248 Infertility, Male Ethinyl Estradiol 15.4017937319
MESH:D007248 Infertility, Male Lead 15.4016780224
MESH:D007248 Infertility, Male methyl cellosolve 15.403987992
MESH:D007248 Infertility, Male sodium arsenite 15.4012646999 15346721
MESH:D007248 Infertility, Male vinclozolin 15.4016467254
MESH:D007249 Inflammation Aluminum 48.4916052892
MESH:D007249 Inflammation Curcumin 48.4916956363 18403477 17151092
MESH:D007249 Inflammation Diethylnitrosamine 48.4918785209
MESH:D007249 Inflammation Flurbiprofen 48.4911099482
MESH:D007249 Inflammation Heme 48.4912649161
MESH:D007249 Inflammation Ibuprofen 48.493291741
MESH:D007249 Inflammation Indomethacin 48.493291741 7812673 12568917
MESH:D007249 Inflammation Lipopolysaccharides 48.4917963957 9205823 17255318 12878042 17237260
MESH:D007249 Inflammation Mustard Gas 48.4911428647 17524151 16001271 8975870 9357497 9260866 11402378 11428620 11428631
MESH:D007249 Inflammation Nickel 48.4916166738
MESH:D007249 Inflammation pioglitazone 48.4916908763
MESH:D007249 Inflammation Plant Extracts 48.4916366677 15997105 12787963 19332304
MESH:D007249 Inflammation Progesterone 48.4915869954
MESH:D007249 Inflammation resveratrol 48.4916366677
MESH:D007249 Inflammation rosiglitazone 48.4912083418
MESH:D007249 Inflammation Sulindac 48.493291741
MESH:D007249 Inflammation Tamoxifen 48.4919457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 48.4912200463 12878042
MESH:D015212 Inflammatory Bowel Diseases Curcumin 2.6118596194 18200517
MESH:D007251 Influenza, Human Quercetin 17.4216624496
MESH:D007251 Influenza, Human resveratrol 17.4216624496
MESH:D007251 Influenza, Human Selenium 17.4216624496
MESH:D007251 Influenza, Human Vitamin E 17.4216624496
MESH:D007333 Insulin Resistance pirinixic acid 4.6916306350
MESH:D007333 Insulin Resistance rosiglitazone 4.6916306350
MESH:D007410 Intestinal Diseases Indomethacin 14.6311855677 11713966 11686837 18236018 17994277 10210152 17329856 15831440 15610444
MESH:D007410 Intestinal Diseases Nitric Oxide 14.6311574821 10210152 11713966
MESH:D007410 Intestinal Diseases Superoxides 14.6310210152
MESH:D007410 Intestinal Diseases Tretinoin 14.6317994277
MESH:D007414 Intestinal Neoplasms Curcumin 10.7210783313
MESH:D007414 Intestinal Neoplasms Plant Extracts 10.7212584176 12351151 12628509
MESH:D007414 Intestinal Neoplasms Sulindac 10.7212351151 12628509 12584176 10223192 12663524 10213222
MESH:D007417 Intestinal Polyps Sulindac 3.9311245490 12394442
MESH:D002532 Intracranial Aneurysm Reactive Oxygen Species 4.0019381132
MESH:D019586 Intracranial Hypertension Indomethacin 10.4115241188
MESH:D019586 Intracranial Hypertension Vitamin A 10.4115955940
MESH:D019189 Iron Metabolism Disorders Iron 8.0817163184
MESH:D019189 Iron Metabolism Disorders Lipopolysaccharides 8.0817255318
MESH:D007511 Ischemia morin 7.8416806951
MESH:D007511 Ischemia Zinc 7.8416584753
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 11.3016580747
MESH:D007569 Jaw Abnormalities Tretinoin 11.3017551590 15992940
MESH:D007569 Jaw Abnormalities triadimefon 11.3015992940 15834900
MESH:D007579 Jejunal Diseases Indomethacin 3.8910574470 18306037 16133968
MESH:D007627 Keloid Quercetin 3.8517086741
MESH:D007674 Kidney Diseases Acrolein 23.6812488133
MESH:D007674 Kidney Diseases Cadmium 23.6816226777 16322080 16962696
MESH:D007674 Kidney Diseases Dichlorvos 23.6816798900
MESH:D007674 Kidney Diseases Doxorubicin 23.6815369732 15699352 16775033
MESH:D007674 Kidney Diseases Indomethacin 23.6817190690
MESH:D007674 Kidney Diseases Quercetin 23.6816962696
MESH:D007674 Kidney Diseases sodium arsenite 23.6820008137
MESH:D007674 Kidney Diseases Vitamin E 23.6812488133
MESH:D007674 Kidney Diseases Zinc 23.6816960431
MESH:D007676 Kidney Failure, Chronic Copper 20.4316518626
MESH:D007676 Kidney Failure, Chronic Doxorubicin 20.4316707910
MESH:D007676 Kidney Failure, Chronic Hydrogen Peroxide 20.4316518626
MESH:D007676 Kidney Failure, Chronic Selenium 20.4316518626
MESH:D007676 Kidney Failure, Chronic Zinc 20.4316518626
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 4.2516705839
MESH:D007680 Kidney Neoplasms Tamoxifen 4.2518625569
MESH:D007683 Kidney Tubular Necrosis, Acute Calcium 3.9116316344
MESH:D007855 Lead Poisoning Lead 4.8116700817
MESH:D007859 Learning Disorders Cholesterol 14.2017134702
MESH:D007859 Learning Disorders Copper 14.2017134702
MESH:D007859 Learning Disorders icariin 14.2019782061
MESH:D007859 Learning Disorders Lead 14.2016384672
MESH:D007889 Leiomyoma Curcumin 3.5118555241
MESH:D007896 Leishmaniasis Amphotericin B 6.7520404924 21063981 17205440
MESH:D007896 Leishmaniasis Nitric Oxide 6.7517218153
MESH:D016773 Leishmaniasis, Cutaneous Indomethacin 2.9611703811 12228301 10320625
MESH:D007898 Leishmaniasis, Visceral Amphotericin B 4.619625910 7983993 10603400 17911647 9756784 9498473 18087708 17035822 16269185 15868188 16131481 18765878 10569788 11049798
MESH:D007938 Leukemia 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 18.7112970779
MESH:D007938 Leukemia arsenic trioxide 18.7115070760
MESH:D007938 Leukemia Benzene 18.7118335105 17119257 14694614 15935818
MESH:D007938 Leukemia Curcumin 18.7118462866
MESH:D007938 Leukemia kaempferol 18.7117468513
MESH:D007938 Leukemia Quercetin 18.7117468513
MESH:D007938 Leukemia Tretinoin 18.7117143497
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 4.0116085563
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 6.3412560223 17077332
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Curcumin 6.3416106398
MESH:D007948 Leukemia, Monocytic, Acute anthra(1,9-cd)pyrazol-6(2H)-one 13.2516972261
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 13.2516972261
MESH:D007948 Leukemia, Monocytic, Acute PD 98059 13.2516972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 5.5214633726
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Indomethacin 5.5216572323 10785260 15631656
MESH:D007951 Leukemia, Myeloid arsenic trioxide 10.1019077051
MESH:D007951 Leukemia, Myeloid Benzene 10.1017506065
MESH:D007951 Leukemia, Myeloid Tretinoin 10.1016482212 16932348 19285840
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 5.5716968895 16467208 17050201 20471514 19850784
MESH:D015470 Leukemia, Myeloid, Acute Benzene 5.5719478238
MESH:D015470 Leukemia, Myeloid, Acute Indomethacin 5.5718360721
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 5.5719850784 17596541 16294345
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 7.8517107899 17649720 11468182 16966277 17712046 19075265 12712474 16891316 9834237 19225113 16330433 19642359 16112521 19035177 15622746 16823087 17869043 11161223 17217047 15213294 12679006 15336539 12018890 16331271 15748426
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 7.8516087638
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 7.8516331271 12679006 16935935 16891316 19029980 17294898 16766008 17649720 17301526 17506722 19225113 19075265 17368321 16788101 17217047 17361223 15748426 16823087 9834237 17712046 17339181 16140955 19642359 17107899 19035177
MESH:D015458 Leukemia, T-Cell arsenic trioxide 8.1316882451
MESH:D015458 Leukemia, T-Cell Curcumin 8.1316106398
MESH:D007964 Leukocytosis Indomethacin 4.2316537180
MESH:D007969 Leukomalacia, Periventricular Indomethacin 4.5717980183
MESH:D007970 Leukopenia Lipopolysaccharides 3.5815821434
MESH:D020961 Lewy Body Disease Iron 4.3216563566
MESH:D007984 Leydig Cell Tumor vinclozolin 3.6116417039
MESH:D017880 Limb Deformities, Congenital methyl cellosolve 8.736499821
MESH:D017880 Limb Deformities, Congenital Tretinoin 8.739224671
MESH:D017880 Limb Deformities, Congenital Vitamin A 8.7316054864
MESH:D008064 Lipidoses Tamoxifen 2.2815342952 17567588
MESH:D008101 Liver Abscess, Amebic Indomethacin 4.5711479899
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 12.6621278145 17157831 11903743 16943688 17334410 11408273 17174718 16221502 16239168
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 12.6618665156 20032147 18407596 19638242 18522880
MESH:D008103 Liver Cirrhosis Iron 12.6616640825
MESH:D008103 Liver Cirrhosis Plant Extracts 12.6617157831
MESH:D008103 Liver Cirrhosis Vitamin A 12.6616256175
MESH:D008105 Liver Cirrhosis, Biliary Sulindac 3.4012468960
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 37.1015370692 18429990 15931870 17766677 17944888 12632512 15650968 13678700 20821823 18251166 12389079 18376398 16097048 18279442 15925388 17900296 15052691 17525996 18317297 15123356 11481614 17721639 18481824 16192424 18054572 17761835 18166357 15818738 18705752 16011737 15057751 12741479 16638106 17714472 15893842 15362042 16116963 12609069 12445418 15876570 17698563 18263696 17922224 12586293 18006644 17976157 14620537 18156304 14512876 18187930 16033810 12958196 14724832 14716833 17565644 18418968 14716496 17640975 18395914 15959796 16015684 17631135 15730626 16027843 12649538 18395095 12546737 18339082 15673190 17708605 17557913 12445421 18472332 12667390 17869086 15996030 17481882 18420326 12898905 18205269 12632514 10355542 14748882 16136751 17805973 18412020 15338365 16248980 12666154 18277467 17823541 18210741 18472094
MESH:D008106 Liver Cirrhosis, Experimental Curcumin 37.1017355460 18006644 18705752
MESH:D008106 Liver Cirrhosis, Experimental Dinoprostone 37.1015816358
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 37.1016595196 16439617
MESH:D008106 Liver Cirrhosis, Experimental Fenofibrate 37.1015474484
MESH:D008106 Liver Cirrhosis, Experimental Heparin 37.1016904936
MESH:D008106 Liver Cirrhosis, Experimental Indomethacin 37.1018194892
MESH:D008106 Liver Cirrhosis, Experimental Lipopolysaccharides 37.1012878042
MESH:D008106 Liver Cirrhosis, Experimental Melatonin 37.1015298665 16703270 15925388
MESH:D008106 Liver Cirrhosis, Experimental morin 37.1018629640
MESH:D008106 Liver Cirrhosis, Experimental pioglitazone 37.1015052691 16484506
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 37.1015474484
MESH:D008106 Liver Cirrhosis, Experimental Plant Extracts 37.1015479170
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 37.1012741479
MESH:D008106 Liver Cirrhosis, Experimental rosiglitazone 37.1017347453 15980055
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 37.1018564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 37.1012878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 37.1016248980 18397230
MESH:D008106 Liver Cirrhosis, Experimental Vitamin A 37.1016248980
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 37.1016169303
MESH:D008106 Liver Cirrhosis, Experimental Y 27632 37.1013678700
MESH:D008107 Liver Diseases Carbon Tetrachloride 16.9716964402 15830285 16246199 15720792 17285989
MESH:D008107 Liver Diseases Curcumin 16.9716956363
MESH:D008107 Liver Diseases Diethylnitrosamine 16.9717034775
MESH:D008107 Liver Diseases Dinoprostone 16.9715816358
MESH:D008107 Liver Diseases Plant Extracts 16.9717034775
MESH:D008107 Liver Diseases propiconazole 16.9719363144
MESH:D008107 Liver Diseases Sulindac 16.9714986274 16867024
MESH:D008107 Liver Diseases triadimefon 16.9719363144
MESH:D008107 Liver Diseases Vitamin A 16.9716175620
MESH:D008108 Liver Diseases, Alcoholic Iron 8.0317207112 16737972
MESH:D008108 Liver Diseases, Alcoholic Vitamin A 8.0316762690
MESH:D017093 Liver Failure Carbon Tetrachloride 3.0615123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 2.6814706259 16899240
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 47.037678174
MESH:D008113 Liver Neoplasms arsenic trioxide 47.0314682389
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 47.0319294768
MESH:D008113 Liver Neoplasms Clofibric Acid 47.0317602206
MESH:D008113 Liver Neoplasms Copper 47.0320302851
MESH:D008113 Liver Neoplasms Diethylnitrosamine 47.0320405173 20501860 9163691 2422723 19499222 19642983 21278145 18978307 19256749 20583210 20137499 19996281 19812893 21167192 19427195 19090486 20492335 18977376 16942905 15885732 10737359 19254457 19833225 21071580 20452335 20101389 19638242 19255062 12771043 18648771 21047994 20434301 18644402 15175105 19690152 19294768 12112319 2862719 19426721 19073162 18754104 20118626 19850985 19551842
MESH:D008113 Liver Neoplasms Fenofibrate 47.0318978307
MESH:D008113 Liver Neoplasms Iron 47.0320302851 16640825
MESH:D008113 Liver Neoplasms Mitomycin 47.0315113037
MESH:D008113 Liver Neoplasms pirinixic acid 47.0320007298 15890375 16377806
MESH:D008113 Liver Neoplasms Plant Extracts 47.0319168119
MESH:D008113 Liver Neoplasms propiconazole 47.0319028983
MESH:D008113 Liver Neoplasms Quercetin 47.0318980244
MESH:D008113 Liver Neoplasms resveratrol 47.0319812893 19073162 19321006 20405173
MESH:D008113 Liver Neoplasms sodium arsenite 47.0315276417 16712894
MESH:D008113 Liver Neoplasms Tamoxifen 47.0316684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 47.0316984957
MESH:D008113 Liver Neoplasms triadimefon 47.0319028983
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 44.222876784 6135515 2876786
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 44.2220377131
MESH:D008114 Liver Neoplasms, Experimental Benzene 44.2212562636
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 44.2212014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 44.222563599 18079962 9362446 18544905 18282651 17942915 17174075 3124819 17854601 18093689 19519916 18164116 16842330 19126423 18308698 18775883 19004024 18253720 21159647 19539802 19009564 16267830
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 44.2216842330 17085340
MESH:D008114 Liver Neoplasms, Experimental Fenofibrate 44.2218253720 18775883
MESH:D008114 Liver Neoplasms, Experimental kojic acid 44.2218544905
MESH:D008114 Liver Neoplasms, Experimental morin 44.2219539802
MESH:D008114 Liver Neoplasms, Experimental propiconazole 44.2217178689
MESH:D008114 Liver Neoplasms, Experimental Quercetin 44.2219519916
MESH:D008114 Liver Neoplasms, Experimental systhane 44.2217178689
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 44.2212151625
MESH:D008114 Liver Neoplasms, Experimental triadimefon 44.2217178689
MESH:D008114 Liver Neoplasms, Experimental Vitamin A 44.2217113696
MESH:D008133 Long QT Syndrome arsenic trioxide 2.4415213294
MESH:D008171 Lung Diseases Acrolein 21.6111504702
MESH:D008171 Lung Diseases Aluminum 21.6116052892
MESH:D008171 Lung Diseases Mustard Gas 21.6118702808 18161513
MESH:D008171 Lung Diseases Ozone 21.6119066396 8266340
MESH:D008171 Lung Diseases sodium arsenite 21.6119095001
MESH:D008171 Lung Diseases Vitamin A 21.6116863852
MESH:D008171 Lung Diseases Vitamin E 21.6116863852
MESH:D017563 Lung Diseases, Interstitial Benzene 3.6714698565
MESH:D055370 Lung Injury Lipopolysaccharides 9.0821114838
MESH:D055370 Lung Injury Nitric Oxide 9.0811395602
MESH:D055370 Lung Injury Ozone 9.0820417186
MESH:D008175 Lung Neoplasms arsenic trioxide 28.8419825857 11798837
MESH:D008175 Lung Neoplasms Benzene 28.8412562636
MESH:D008175 Lung Neoplasms bexarotene 28.8417849452
MESH:D008175 Lung Neoplasms Curcumin 28.8418462866 19359593 16243823
MESH:D008175 Lung Neoplasms Diethylnitrosamine 28.846695378 20970405 20512841 21163286
MESH:D008175 Lung Neoplasms Doxorubicin 28.846189445 17418594
MESH:D008175 Lung Neoplasms Indomethacin 28.8411497255 11053908 16537180
MESH:D008175 Lung Neoplasms Iron 28.8416640825
MESH:D008175 Lung Neoplasms Melatonin 28.8417195641
MESH:D008175 Lung Neoplasms Mustard Gas 28.848781369 3148597
MESH:D008175 Lung Neoplasms Ozone 28.847614698 8597069
MESH:D008175 Lung Neoplasms Plant Extracts 28.8420869020
MESH:D008175 Lung Neoplasms Quercetin 28.8416280456
MESH:D008175 Lung Neoplasms sodium arsenite 28.8416712894 17077188 17306315 19931552 15276417
MESH:D008175 Lung Neoplasms Sulindac 28.8415713900 19359593
MESH:D008175 Lung Neoplasms Tamoxifen 28.8418625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 28.8411884234 19555203
MESH:D008175 Lung Neoplasms Vitamin E 28.8411062179
MESH:D008180 Lupus Erythematosus, Systemic Melatonin 3.4616373423
MESH:D008223 Lymphoma Benzene 10.6817584886 17119257
MESH:D008223 Lymphoma Curcumin 10.6818462866
MESH:D008223 Lymphoma Doxorubicin 10.6816098063
MESH:D008223 Lymphoma Nitric Oxide 10.6816166326
MESH:D016393 Lymphoma, B-Cell resveratrol 3.2517088997
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 5.6717654614
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 5.6714749477
MESH:D016399 Lymphoma, T-Cell Curcumin 7.9216173963
MESH:D016399 Lymphoma, T-Cell Doxorubicin 7.9215621674
MESH:D016410 Lymphoma, T-Cell, Cutaneous bexarotene 4.0411161223
MESH:D008231 Lymphopenia methyl cellosolve 4.653699323
MESH:D008268 Macular Degeneration Iron 3.2316640825
MESH:D015674 Mammary Neoplasms, Animal Benzene 10.4112562636
MESH:D015674 Mammary Neoplasms, Animal resveratrol 10.4115688416
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 10.4119428831
MESH:D008325 Mammary Neoplasms, Experimental Benzene 29.2111921183
MESH:D008325 Mammary Neoplasms, Experimental bexarotene 29.2115591091 19196723 19196722
MESH:D008325 Mammary Neoplasms, Experimental celecoxib 29.2119196722 12104042
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 29.2115458769
MESH:D008325 Mammary Neoplasms, Experimental Ibuprofen 29.2110697514
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 29.2111408345 17203775
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 29.218985016 11606380
MESH:D008325 Mammary Neoplasms, Experimental rosiglitazone 29.2116827153
MESH:D008325 Mammary Neoplasms, Experimental Selenium 29.2115318939
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 29.2116827153 11731420 19196722 14580682 19196723
MESH:D008325 Mammary Neoplasms, Experimental Zinc 29.2112773700
MESH:D020149 Manganese Poisoning Manganese 9.2516551646 19453300 16568477
MESH:D020149 Manganese Poisoning Tamoxifen 9.2519453300
MESH:D008527 Medulloblastoma Tretinoin 2.1817453147
MESH:D008545 Melanoma Acridine Orange 13.8616814760
MESH:D008545 Melanoma Curcumin 13.8617885582 18462866
MESH:D008545 Melanoma Doxorubicin 13.8616827129
MESH:D008545 Melanoma Reactive Oxygen Species 13.8617992120
MESH:D008545 Melanoma resveratrol 13.8617992120
MESH:D008545 Melanoma sodium arsenite 13.8619082730 16487513
MESH:D008545 Melanoma Sulindac 13.8616642371
MESH:D008545 Melanoma Tamoxifen 13.8619393235 12393984
MESH:D008545 Melanoma Tretinoin 13.8616752155
MESH:D018328 Melanoma, Amelanotic Tamoxifen 3.0615990972
MESH:D008546 Melanoma, Experimental Acrolein 4.1110803710
MESH:D008569 Memory Disorders Curcumin 14.1817263510
MESH:D008569 Memory Disorders icariin 14.1819782061
MESH:D008569 Memory Disorders Lead 14.1816384672 17263510
MESH:D008569 Memory Disorders Trichlorfon 14.1815957009
MESH:D008591 Meningomyelocele Homocysteine 8.7716602021
MESH:D008591 Meningomyelocele Tretinoin 8.7716940565
MESH:D007706 Menkes Kinky Hair Syndrome Copper 4.7517268249 17109627
MESH:D001523 Mental Disorders Phosphates 3.9812686366
MESH:D008654 Mesothelioma Doxorubicin 4.1917638057
MESH:D008654 Mesothelioma Selenium 4.1915107826
MESH:D008659 Metabolic Diseases resveratrol 3.3417112576
MESH:D024821 Metabolic Syndrome X rosiglitazone 3.4117261469
MESH:D008679 Metaplasia Ozone 3.9610496685
MESH:D008881 Migraine Disorders Indomethacin 5.1811903285
MESH:D008881 Migraine Disorders Nitric Oxide 5.1811701602
MESH:D020326 Migraine without Aura Dinoprostone 7.6411304026
MESH:D020326 Migraine without Aura Nitric Oxide 7.6411304026 14659530
MESH:D028361 Mitochondrial Diseases Doxorubicin 3.4615792986
MESH:D016472 Motor Neuron Disease Dichlorvos 5.2011282359
MESH:D009062 Mouth Neoplasms Indomethacin 3.0712636206
MESH:D009069 Movement Disorders Manganese 3.9516551646
MESH:D052016 Mucositis Doxorubicin 3.6717415656
MESH:D009101 Multiple Myeloma arsenic trioxide 16.8615949261 14977855 11468182 19417148 19549372
MESH:D009101 Multiple Myeloma Benzene 16.8617119195
MESH:D009101 Multiple Myeloma celecoxib 16.8616123214
MESH:D009101 Multiple Myeloma Curcumin 16.8619372569
MESH:D009101 Multiple Myeloma resveratrol 16.8617164350 16267019 17049120 17935668 16490592 14749477
MESH:D009101 Multiple Myeloma Vitamin A 16.8616374440
MESH:D020528 Multiple Sclerosis, Chronic Progressive Aluminum 10.7217086897
MESH:D020528 Multiple Sclerosis, Chronic Progressive Iron 10.7217086897
MESH:D020529 Multiple Sclerosis, Relapsing-Remitting Aluminum 5.2317086897
MESH:D009134 Muscular Atrophy, Spinal Curcumin 8.7017962980
MESH:D009134 Muscular Atrophy, Spinal resveratrol 8.7017962980
MESH:D009135 Muscular Diseases pirinixic acid 2.4116239165
MESH:D009181 Mycoses Iron 4.3316640825
MESH:D009182 Mycosis Fungoides arsenic trioxide 3.5318349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 4.7716105982 16882451
MESH:D009190 Myelodysplastic Syndromes Tretinoin 4.7717596541
MESH:D009203 Myocardial Infarction Doxorubicin 17.1919429709 15857846
MESH:D009203 Myocardial Infarction Homocysteine 17.1917412321
MESH:D009203 Myocardial Infarction Lithium 17.1916288908
MESH:D009203 Myocardial Infarction pirinixic acid 17.1919151258
MESH:D009203 Myocardial Infarction Quercetin 17.1919595682
MESH:D009203 Myocardial Infarction resveratrol 17.1916317513 16525036 16456233 17188708 17015251 17125593
MESH:D009203 Myocardial Infarction tris(acetylacetonate) aluminum(III) 17.193270516
MESH:D017202 Myocardial Ischemia Iron 9.8516604332
MESH:D017202 Myocardial Ischemia resveratrol 9.8517015251 17125593
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 9.8512213967
MESH:D015428 Myocardial Reperfusion Injury Iron 8.9316604332
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 8.9316411023
MESH:D015428 Myocardial Reperfusion Injury Quercetin 8.9319207477
MESH:D009205 Myocarditis Particulate Matter 8.7112563109
MESH:D009205 Myocarditis resveratrol 8.7117322642
MESH:D009224 Myotonia Congenita Quinine 5.121896199
MESH:D009336 Necrosis 2,6-dinitrotoluene 11.6618551238 7678174
MESH:D009336 Necrosis 2-ethoxyethanol 11.6620172899
MESH:D009336 Necrosis Melatonin 11.6612195237
MESH:D009349 Nematode Infections Dichlorvos 5.0016402567
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 6.7616624393
MESH:D009361 Neoplasm Invasiveness Curcumin 6.7618495463
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 8.373581430 9029167
MESH:D009362 Neoplasm Metastasis Doxorubicin 8.3718259882
MESH:D009362 Neoplasm Metastasis Indomethacin 8.3711239499 11053908 16537180
MESH:D009362 Neoplasm Metastasis Tamoxifen 8.3719393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.0019410462
MESH:D009369 Neoplasms 4-phenylbutyric acid 15.8519116145
MESH:D009369 Neoplasms Acrolein 15.8517329238
MESH:D009369 Neoplasms meloxicam 15.8516684565
MESH:D009369 Neoplasms Nicotine 15.8516365874
MESH:D009369 Neoplasms pirinixic acid 15.8517405874
MESH:D009369 Neoplasms Quercetin 15.8515185748
MESH:D009369 Neoplasms sodium arsenite 15.8511559025
MESH:D009369 Neoplasms Tretinoin 15.8516946489 16594593
MESH:D009374 Neoplasms, Experimental Indomethacin 9.0915625704 10663608
MESH:D009374 Neoplasms, Experimental resveratrol 9.098985016
MESH:D009374 Neoplasms, Experimental sodium arsenite 9.0920056578
MESH:D009376 Neoplasms, Hormone-Dependent bexarotene 16.9319196722
MESH:D009376 Neoplasms, Hormone-Dependent celecoxib 16.9319196722
MESH:D009376 Neoplasms, Hormone-Dependent Curcumin 16.9312497104
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 16.9319189210 19196722 19200415
MESH:D009389 Neovascularization, Pathologic Copper 7.1217308104
MESH:D009389 Neovascularization, Pathologic Nicotine 7.1216365874
MESH:D009393 Nephritis Acrolein 5.1412653641
MESH:D009395 Nephritis, Interstitial Ibuprofen 3.866375363
MESH:D009401 Nephrosis Doxorubicin 3.6716636307 16899518
MESH:D009404 Nephrotic Syndrome Doxorubicin 6.4616889571 15640375
MESH:D009404 Nephrotic Syndrome Iron 6.4617178036
MESH:D009410 Nerve Degeneration Dichlorvos 9.0517850875 11282359
MESH:D009410 Nerve Degeneration Ibuprofen 9.0510961664
MESH:D009410 Nerve Degeneration Manganese 9.0516551646
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 5.9614600291
MESH:D009421 Nervous System Malformations Tretinoin 5.969125849
MESH:D009423 Nervous System Neoplasms Curcumin 4.4818462866
MESH:D009436 Neural Tube Defects arsenic trioxide 13.8610525206
MESH:D009436 Neural Tube Defects Benzene 13.8615643154
MESH:D009436 Neural Tube Defects sodium arsenite 13.8612854658
MESH:D009436 Neural Tube Defects Tretinoin 13.869142499
MESH:D009436 Neural Tube Defects Vitamin A 13.8617400914
MESH:D019954 Neurobehavioral Manifestations Plant Extracts 4.0817168769
MESH:D009447 Neuroblastoma Acridine Orange 5.4316814760
MESH:D009447 Neuroblastoma Doxorubicin 5.4315555623
MESH:D019636 Neurodegenerative Diseases Acrolein 29.4611342003
MESH:D019636 Neurodegenerative Diseases Dichlorvos 29.4616635102
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 29.4620387270
MESH:D019636 Neurodegenerative Diseases Indomethacin 29.4612349958
MESH:D019636 Neurodegenerative Diseases Iron 29.4617296847 16604332
MESH:D019636 Neurodegenerative Diseases Nimodipine 29.4616635102
MESH:D019636 Neurodegenerative Diseases resveratrol 29.4617652729
MESH:D019636 Neurodegenerative Diseases Sulindac 29.4617266991 16850258
MESH:D020078 Neurogenic Inflammation Quercetin 7.1917929310
MESH:D020078 Neurogenic Inflammation resveratrol 7.1917929310
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 3.9720387270
MESH:D020258 Neurotoxicity Syndromes Dichlorvos 3.9212186780
MESH:D009503 Neutropenia Mustard Gas 2.9416761898 7688884
MESH:D052556 Niemann-Pick Disease, Type C Cholesterol 4.609802331 20557099
MESH:D009765 Obesity Curcumin 4.8019297423
MESH:D009765 Obesity pirinixic acid 4.8020558911
MESH:D009765 Obesity Plant Extracts 4.8020132043 19056576
MESH:D007752 Obstetric Labor, Premature Indomethacin 4.036374098
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 5.8216049721
MESH:D009784 Occupational Diseases Benzene 5.8215935809 15727169 17479406 17119257 17178637 15612468 15576619 16737584 15913788
MESH:D009845 Oligospermia 2-ethoxyethanol 7.6820172899
MESH:D009845 Oligospermia methyl cellosolve 7.683987992
MESH:D010003 Osteoarthritis Ibuprofen 8.087009135
MESH:D010003 Osteoarthritis Indomethacin 8.087009135
MESH:D010003 Osteoarthritis Iron 8.0816640825
MESH:D010005 Osteoarthropathy, Secondary Hypertrophic Dinoprostone 5.3318500342
MESH:D010024 Osteoporosis Calcium 13.6117882678
MESH:D010024 Osteoporosis Curcumin 13.6118719352
MESH:D010024 Osteoporosis icariin 13.6119747809 18236786
MESH:D010024 Osteoporosis Iron 13.6116648989 16640825
MESH:D010024 Osteoporosis kaempferol 13.6116756079
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 6.7119495926
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 6.7117513867
MESH:D012516 Osteosarcoma Doxorubicin 3.1615930896
MESH:D010051 Ovarian Neoplasms 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 17.3816211241
MESH:D010051 Ovarian Neoplasms arsenic trioxide 17.3812452020 19769630 16624393
MESH:D010051 Ovarian Neoplasms Benzene 17.3812562636
MESH:D010051 Ovarian Neoplasms Curcumin 17.3819020741 18462866
MESH:D010051 Ovarian Neoplasms Progesterone 17.3817393432 16525653
MESH:D010051 Ovarian Neoplasms Quercetin 17.3819005980
MESH:D010051 Ovarian Neoplasms sodium arsenite 17.3815276417 17306315
MESH:D010051 Ovarian Neoplasms Tretinoin 17.3816936753
MESH:D010146 Pain DP 155 11.3117627676
MESH:D010146 Pain Ibuprofen 11.313291741
MESH:D010146 Pain Indomethacin 11.3117627676 13679232 17440234 3291741
MESH:D010146 Pain Sulindac 11.313291741
MESH:D010146 Pain Tretinoin 11.3116870215
MESH:D010149 Pain, Postoperative Ibuprofen 7.7116678543
MESH:D010149 Pain, Postoperative Indomethacin 7.7118702446 12538197
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 22.0915580305
MESH:D010190 Pancreatic Neoplasms Curcumin 22.0919196508 17440100 19401701
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 22.0916540662
MESH:D010190 Pancreatic Neoplasms Ibuprofen 22.0912384795
MESH:D010190 Pancreatic Neoplasms Mitomycin 22.0915113037
MESH:D010190 Pancreatic Neoplasms Quercetin 22.0916965848
MESH:D010190 Pancreatic Neoplasms Reactive Oxygen Species 22.0915580305
MESH:D010190 Pancreatic Neoplasms Sulindac 22.0916820089 11504793
MESH:D010190 Pancreatic Neoplasms Tretinoin 22.0915976015
MESH:D010195 Pancreatitis Dichlorvos 5.6516258382
MESH:D010195 Pancreatitis Indomethacin 5.6515028970 17883296
MESH:D016584 Panic Disorder Ethinyl Estradiol 2.6311578682
MESH:D010212 Papilloma Hydrogen Peroxide 9.5212065085
MESH:D010212 Papilloma Iron 9.5212065085
MESH:D010212 Papilloma Plant Extracts 9.5215173996 16517061
MESH:D010235 Paraganglioma arsenic trioxide 3.1019927285
MESH:D010257 Paraneoplastic Syndromes Indomethacin 4.5716537180
MESH:D020447 Parasomnias Iron 4.8717352947
MESH:D010300 Parkinson Disease Acrolein 9.9217690948
MESH:D010300 Parkinson Disease Cholesterol, Dietary 9.9219014385
MESH:D010300 Parkinson Disease Homocysteine 9.9216275827
MESH:D010300 Parkinson Disease Iron 9.9216640825 16563566
MESH:D010300 Parkinson Disease Manganese 9.9211181820
MESH:D010302 Parkinson Disease, Secondary Dichlorvos 4.5112645970
MESH:D020734 Parkinsonian Disorders Indomethacin 9.7012349958
MESH:D020734 Parkinsonian Disorders Manganese 9.7016140633
MESH:D020734 Parkinsonian Disorders Melatonin 9.7015574749
MESH:D051302 Paroxysmal Hemicrania Indomethacin 4.5711903285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.1012520081
MESH:D010437 Peptic Ulcer Indomethacin 4.0211148446
MESH:D010518 Periodontitis Indomethacin 3.7817225004
MESH:D016491 Peripheral Vascular Diseases Cadmium 4.2615687053
MESH:D010538 Peritonitis Isoflurane 10.9117414419
MESH:D010538 Peritonitis Melatonin 10.9115707874
MESH:D010538 Peritonitis Ozone 10.9116369182
MESH:D010787 Photosensitivity Disorders 4-hydroxy-2-nonenal 9.6811550810
MESH:D010787 Photosensitivity Disorders Acrolein 9.6811550810
MESH:D003557 Phyllodes Tumor Doxorubicin 4.0117983394
MESH:D010900 Pituitary Diseases Iron 4.5316604332
MESH:D010954 Plasmacytoma Selenium 3.7515087411
MESH:D010997 Pleural Neoplasms Doxorubicin 4.0117638057
MESH:D011014 Pneumonia Lipopolysaccharides 7.4012224865 11605937
MESH:D011014 Pneumonia Ozone 7.4018929643 18381685 18007984
MESH:D011015 Pneumonia, Aspiration Nitric Oxide 4.2218573544
MESH:D011041 Poisoning Dichlorvos 8.7118072136 12460839 15303389 16036766 17603234 17157343
MESH:D011041 Poisoning Iron 8.7116604332
MESH:D011041 Poisoning Mustard Gas 8.7115727166
MESH:D011115 Polyneuropathies Dichlorvos 4.5212563396
MESH:D017119 Porphyria Cutanea Tarda Iron 7.4416640825
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 7.4418163543
MESH:D011230 Precancerous Conditions Diethylnitrosamine 5.942563599
MESH:D011230 Precancerous Conditions Quercetin 5.9419056647
MESH:D011225 Pre-Eclampsia Iron 6.4216640825
MESH:D011225 Pre-Eclampsia Zinc 6.4217114810
MESH:D047928 Premature Birth Indomethacin 4.0217000239
MESH:D011297 Prenatal Exposure Delayed Effects 2-ethoxyethanol 23.736499817 2884743 7198755
MESH:D011297 Prenatal Exposure Delayed Effects Lead 23.7316384672
MESH:D011297 Prenatal Exposure Delayed Effects methyl cellosolve 23.736499817 7974496 12530607
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 23.7316679765
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 23.7311222880 11896295 11399792 11118676
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 23.7318220299 18042343 19015723
MESH:D017096 Prion Diseases Amphotericin B 5.7812755626
MESH:D011469 Prostatic Diseases vinclozolin 3.8118220299
MESH:D011471 Prostatic Neoplasms arsenic trioxide 7.7719131511
MESH:D011471 Prostatic Neoplasms Cadmium 7.7717075824
MESH:D011471 Prostatic Neoplasms celecoxib 7.7715570007 17908994
MESH:D011471 Prostatic Neoplasms Clioquinol 7.7717308104
MESH:D011471 Prostatic Neoplasms Copper 7.7717079463 17308104
MESH:D011471 Prostatic Neoplasms Curcumin 7.7718156803 15129424 12497104 10851300 18226269 18769126 11398177
MESH:D011471 Prostatic Neoplasms Deoxyglucose 7.7718985042
MESH:D011471 Prostatic Neoplasms Dichlorvos 7.7712661182
MESH:D011471 Prostatic Neoplasms Doxorubicin 7.7715897917 16888761 16729912 16868541 15749863 18437689
MESH:D011471 Prostatic Neoplasms Flurbiprofen 7.7717409433
MESH:D011471 Prostatic Neoplasms Ibuprofen 7.7717409433
MESH:D011471 Prostatic Neoplasms Plant Extracts 7.7717804756 14666653
MESH:D011471 Prostatic Neoplasms Quercetin 7.7714715546 17292933
MESH:D011471 Prostatic Neoplasms resveratrol 7.7717804756 15767336 17636462 17718901 17675339 16731767
MESH:D011471 Prostatic Neoplasms sodium arsenite 7.7716039940
MESH:D011471 Prostatic Neoplasms Tamoxifen 7.7715067354
MESH:D011471 Prostatic Neoplasms Vitamin E 7.7715084515
MESH:D011471 Prostatic Neoplasms Zinc 7.7716606632 12429649 16700911 16517595
MESH:D011472 Prostatitis vinclozolin 3.8118629315
MESH:D011507 Proteinuria Ibuprofen 13.576375363
MESH:D011507 Proteinuria Indomethacin 13.5711849393
MESH:D011507 Proteinuria pioglitazone 13.5716687628
MESH:D011507 Proteinuria Tretinoin 13.5716636307
MESH:D011528 Protozoan Infections Iron 4.8716640825
MESH:D011537 Pruritus Ethinyl Estradiol 5.8516919318 15861022
MESH:D011537 Pruritus Mustard Gas 5.8518058305
MESH:D011625 Pterygium Tretinoin 3.6716723453
MESH:D011649 Pulmonary Alveolar Proteinosis 27-hydroxycholesterol 5.2515466366
MESH:D011656 Pulmonary Emphysema Curcumin 3.5119168576
MESH:D011658 Pulmonary Fibrosis Mustard Gas 4.3217720292 10334151 17620002 17266442 17894541
MESH:D011658 Pulmonary Fibrosis Particulate Matter 4.3212475806
MESH:D012021 Reflex, Abnormal Pentobarbital 4.8910930210
MESH:D051437 Renal Insufficiency Acrolein 6.9712732208
MESH:D051437 Renal Insufficiency Doxorubicin 6.9717922066
MESH:D051436 Renal Insufficiency, Chronic resveratrol 4.4416325855
MESH:D015427 Reperfusion Injury pirinixic acid 6.9719058328
MESH:D015427 Reperfusion Injury resveratrol 6.9715827377 17058453 16314181 17520802 16317513
MESH:D015427 Reperfusion Injury Superoxides 6.9718460982
MESH:D012128 Respiratory Distress Syndrome, Adult Curcumin 3.0010666014 18379247
MESH:D012127 Respiratory Distress Syndrome, Newborn Vitamin A 4.6816877224
MESH:D012130 Respiratory Hypersensitivity Acetylcholine 5.719413022
MESH:D012130 Respiratory Hypersensitivity Lipopolysaccharides 5.7110835634
MESH:D012131 Respiratory Insufficiency Dichlorvos 4.5717350689 15303389
MESH:D012135 Respiratory Sounds Dichlorvos 4.1617119214 16611668
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 2.7518990726
MESH:D012140 Respiratory Tract Diseases Dichlorvos 4.3716611668 17119214
MESH:D012148 Restless Legs Syndrome Iron 3.6216930377
MESH:D012162 Retinal Degeneration Zinc 3.2116584753
MESH:D012208 Rhabdomyosarcoma Tretinoin 3.0416283617 16116481
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.3018045962
MESH:D012509 Sarcoma Curcumin 6.2218462866
MESH:D012509 Sarcoma Doxorubicin 6.2215625365 17203757 15675481 16767912 18313854 17710206
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 6.7116646077
MESH:D012512 Sarcoma, Ewing's Doxorubicin 6.7116326096 14601052
MESH:D012514 Sarcoma, Kaposi Doxorubicin 3.6717846226
MESH:D012554 Schistosomiasis japonica Quercetin 4.4016862918
MESH:D012555 Schistosomiasis mansoni Nitric Oxide 4.379673227
MESH:D012559 Schizophrenia Copper 3.3416842975
MESH:D012559 Schizophrenia Homocysteine 3.3416641680
MESH:D012640 Seizures 2,6-dinitrotoluene 24.6318551238
MESH:D012640 Seizures cyclonite 24.6319417177
MESH:D012640 Seizures Deoxyglucose 24.6317978042
MESH:D012640 Seizures Dichlorvos 24.6317157343 12660363
MESH:D012640 Seizures Dizocilpine Maleate 24.6311218047 17157343 12660363
MESH:D012640 Seizures Lithium 24.6319660546
MESH:D012640 Seizures Mecamylamine 24.6312660363
MESH:D012640 Seizures Nicotine 24.6317873105
MESH:D012640 Seizures Pentobarbital 24.639754883 10087439
MESH:D012640 Seizures Pentylenetetrazole 24.6315475178 3352866 2616065 6431079 18164287 19660546 16054440 18657176 3037702 8954991
MESH:D018805 Sepsis Curcumin 6.5818389075
MESH:D018805 Sepsis Isoflurane 6.5817414419
MESH:D012772 Shock, Septic endotoxin, Escherichia coli 4.5218063050
MESH:D012851 Sinus Thrombosis, Intracranial Heparin 4.9512269725
MESH:D012871 Skin Diseases Mustard Gas 5.2512880345 15451306 16961503
MESH:D012871 Skin Diseases Vitamin A 5.2518709164
MESH:D012871 Skin Diseases Vitamin E 5.2518709164
MESH:D012878 Skin Neoplasms Doxorubicin 23.1715692506
MESH:D012878 Skin Neoplasms Hydrogen Peroxide 23.1712065085
MESH:D012878 Skin Neoplasms Iron 23.1712065085
MESH:D012878 Skin Neoplasms Plant Extracts 23.1715173996 16517061
MESH:D012878 Skin Neoplasms resveratrol 23.1715837718 8985016
MESH:D012878 Skin Neoplasms sodium arsenite 23.1718572023 19524636
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 23.178532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 23.1716192470
MESH:D012878 Skin Neoplasms Tretinoin 23.1716467112
MESH:D012893 Sleep Disorders Melatonin 4.3516919138 16897403 18182647
MESH:D020178 Sleep Disorders, Circadian Rhythm Melatonin 5.4918078449 19452292
MESH:D007319 Sleep Initiation and Maintenance Disorders Melatonin 4.1318078449
MESH:D019082 Smith-Lemli-Opitz Syndrome 24-hydroxycholesterol 9.7211254748
MESH:D019082 Smith-Lemli-Opitz Syndrome 27-hydroxycholesterol 9.7211254748
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 3.4717203757 16767912 15625365
OMIM:270800 SPASTIC PARAPLEGIA 5A, AUTOSOMAL RECESSIVE 27-hydroxycholesterol 5.2519812052
MESH:D013088 Spermatocele Ethinyl Estradiol 7.7916709447
MESH:D013088 Spermatocele Tamoxifen 7.7916709447
MESH:D013119 Spinal Cord Injuries Progesterone 7.1716503802 15862959
MESH:D013119 Spinal Cord Injuries Tamoxifen 7.1719457130
MESH:D016135 Spinal Dysraphism sodium arsenite 2.8612854658
MESH:D013226 Status Epilepticus Lithium 4.6519570321 19430551 19951488
MESH:D013272 Stomach Diseases Indomethacin 3.3116184426 18545984 16280098 15472012 18209964 15038085 10192188 16113693 10215738 17638125 10486359 17207306 17160473
MESH:D013274 Stomach Neoplasms arsenic trioxide 6.5817007042
MESH:D013274 Stomach Neoplasms Benzene 6.5812562636
MESH:D013274 Stomach Neoplasms celecoxib 6.5815609394
MESH:D013274 Stomach Neoplasms Dichlorvos 6.5811397402
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 6.5818456281
MESH:D013274 Stomach Neoplasms Indomethacin 6.5815609394
MESH:D013274 Stomach Neoplasms Tretinoin 6.5817261132
MESH:D013276 Stomach Ulcer 2-ethoxyethanol 15.186499799
MESH:D013276 Stomach Ulcer Curcumin 15.1816631530 19188055
MESH:D013276 Stomach Ulcer Indomethacin 15.1811595415 12077510 16631530 15138204 18726076 15104355 17895592 10423059 11906479 1323529 11595431 16397915 17977527 16150113 14567935 10750652 17918041 10878458 16169175 11523592 12787963 18299717 16934674 18543354 18087811 17627676 12498302 12500499 12467913 15255614 17657623 16252198 18181030 11145282 18193104 18431645 18209962 18237397 17654042 17135157 16755016 11729361
MESH:D013276 Stomach Ulcer Melatonin 15.1812500499 16150113 11523592
MESH:D013276 Stomach Ulcer Nitric Oxide 15.1815138204
MESH:D013276 Stomach Ulcer Plant Extracts 15.1818193104 17135157 15255614 18237397 12787963
MESH:D020521 Stroke Acrolein 5.8316269634
MESH:D020521 Stroke Vitamin E 5.8316517955
OMIM:601367 STROKE, ISCHEMIC resveratrol 3.4616321402
MESH:D013322 Strongyloidiasis Dichlorvos 10.2514651886
MESH:D013322 Strongyloidiasis Trichlorfon 10.2514651886
MESH:D013375 Substance Withdrawal Syndrome Pentobarbital 3.9711529278 9754883
MESH:D013398 Sudden Infant Death Iron 4.3216640825
MESH:D013610 Tachycardia Nitroprusside 4.5415306635
MESH:D013705 Temporomandibular Joint Disorders Plant Extracts 4.3417997062
MESH:D013733 Testicular Diseases 2-ethoxyethanol 7.376499806 10048760 10514026
MESH:D013733 Testicular Diseases methyl cellosolve 7.376499806
MESH:D013921 Thrombocytopenia Heparin 6.9416893407 16651880
MESH:D013921 Thrombocytopenia Lipopolysaccharides 6.9415821434
MESH:D019851 Thrombophilia Ethinyl Estradiol 2.5611994571
MESH:D013927 Thrombosis Ethinyl Estradiol 6.2115669648
MESH:D013927 Thrombosis Heparin 6.2116893407
MESH:D013953 Thymus Neoplasms Benzene 3.8410850423
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 8.6012697716
MESH:D013959 Thyroid Diseases Thyroxine 8.6019910387
MESH:D013964 Thyroid Neoplasms arsenic trioxide 19.8419014326
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 19.847505956
MESH:D013964 Thyroid Neoplasms Doxorubicin 19.8416010429 17909728
MESH:D013964 Thyroid Neoplasms Indomethacin 19.8414736730 11352223 18791128
MESH:D013964 Thyroid Neoplasms Propylthiouracil 19.8415710170
MESH:D013964 Thyroid Neoplasms Tretinoin 19.8416026305 17045167
MESH:D013964 Thyroid Neoplasms triadimefon 19.8417178689
OMIM:188890 TOBACCO ADDICTION, SUSCEPTIBILITY TO Nicotine 3.8216785264 16720336 11259349
MESH:D014029 Tobacco Use Disorder Nicotine 4.3517979512 18305452 18041664 15735609
MESH:D014062 Tongue Neoplasms resveratrol 10.8016227395
MESH:D014062 Tongue Neoplasms Tretinoin 10.8016051514
MESH:D014062 Tongue Neoplasms Zinc 10.8016543248
MESH:D016171 Torsades de Pointes arsenic trioxide 2.8515213294
MESH:D014202 Tremor Lead 4.3621145352
MESH:D014376 Tuberculosis Iron 5.4216597321
MESH:D014376 Tuberculosis Tretinoin 5.4216040207
MESH:D014456 Ulcer Indomethacin 3.7710574470 17380554
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 14.5316049721
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 14.5311780464 20435036 12973940 12845720
MESH:D001749 Urinary Bladder Neoplasms Curcumin 14.5318593936
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 14.5317653716
MESH:D001749 Urinary Bladder Neoplasms Quercetin 14.5316720314
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 14.5311723127 17306315 16712894 16452187
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 14.538653321 17572228 16712894
MESH:D014565 Urogenital Neoplasms Curcumin 4.1418462866
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 3.2010091137
MESH:D002583 Uterine Cervical Neoplasms resveratrol 10.0617473185
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 10.0611813266
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 10.0616129372
MESH:D014594 Uterine Neoplasms Benzene 23.6612562636
MESH:D014594 Uterine Neoplasms celecoxib 23.6618645019
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 23.6614692618
MESH:D014594 Uterine Neoplasms resveratrol 23.6617044934
MESH:D014594 Uterine Neoplasms Sulindac 23.6618645019
MESH:D014594 Uterine Neoplasms sulindac sulfide 23.6618645019
MESH:D014604 Uveal Neoplasms Tretinoin 3.4716752155
MESH:D014652 Vascular Diseases sodium arsenite 3.3017056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 3.4512125929
MESH:D014657 Vasculitis Heparin 4.9520337814
MESH:D020301 Vasospasm, Intracranial Ibuprofen 4.0719057314
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 2.5014671159 15869587
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 10.9417678736 17638931 17334414 16364871
MESH:D018487 Ventricular Dysfunction, Left Plant Extracts 10.9418097624
MESH:D018487 Ventricular Dysfunction, Left resveratrol 10.9417488730
MESH:D020257 Ventricular Remodeling Plant Extracts 4.1918097624
MESH:D014802 Vitamin A Deficiency Vitamin A 4.2116146918 16175781 16960172
MESH:D014820 Vitiligo Tretinoin 2.9816761959
MESH:D014839 Vomiting Indomethacin 8.4811897121
MESH:D014839 Vomiting meloxicam 8.4811897121
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.1015886252
MESH:D009396 Wilms Tumor Tretinoin 2.9716287080
MESH:D014947 Wounds and Injuries Heme 6.2012649161
MESH:D014947 Wounds and Injuries Plant Extracts 6.2020213670 19894650
Pathway ID Pathway Name
KEGG:05010 Alzheimer's disease
REACT:604 Hemostasis
REACT:14797 Signaling by GPCR
REACT:6900 Signaling in Immune system
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA24910
    • Releated gene ID Related gene Name
    PA139ACE
    PA27594ECE1
    PA134886910ECE2
    PA29629IDE
    PA30312LCP1
    PA30864MME
    PA30877MMP2
    PA30886MMP3
    PA30889MMP9
    Releated disease ID Related disease Name
    PA446850Blindness, Cortical
    PA443970Dystonia
    PA445021Myoclonus
    PA446858Neurodegenerative Diseases
    PA165110266Posterior Cortical Atrophy
    PA443434Arthritis, Rheumatoid
    PA443933Down Syndrome
    PA443319Alzheimer Disease
    PA151958644Cerebral Hemorrhage with Amyloidosis,Hereditary,Dutch Type (HCHWAD)
    PA444987Multiple Sclerosis
    Releated drug ID Related drug Name
    PA164712308Ace Inhibitors, Plain
    PA450635nitric oxide
    PA449470epinephrine
    PA10004adalimumab
    PA450428methotrexate
    PA10384antiinflammatory and antirheumatic products, non-steroids
    PA449760glatiramer acetate
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB02235 - Methionine Sulfoxide
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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