AutismKB 2.0

Annotation Detail for IL2RB


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Basic Information Top
Gene Symbol:IL2RB ( CD122,P70-75 )
Gene Full Name: interleukin 2 receptor, beta
Band: 22q12.3
Quick LinksEntrez ID:3560; OMIM: 146710; Uniprot ID:IL2RB_HUMAN; ENSEMBL ID: ENSG00000100385; HGNC ID: 6009
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04144Endocytosis
hsa04630Jak-STAT signaling pathway
hsa04060Cytokine-cytokine receptor interaction
Pathway IDPathway Name
Signaling in Immune system
Pathway IDPathway Name
200034IL12-mediated signaling events
200184Downstream signaling in naive CD8+ T cells
200158IL2 signaling events mediated by STAT5
200082IL2-mediated signaling events
200099IL2 signaling events mediated by PI3K
Pathway IDPathway Name
P00036Interleukin signaling pathway
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1809HIV infection
1848Embryoma
1901Endometriosis
2051Leukemia
2068Skin disease
No data
Desease Name
Asthma
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in increased expression of IL2RB mRNAincreases expression 18648102
C430898 AGN 194204 AGN 194204 results in decreased expression of IL2RB mRNAdecreases expression 16339527
D001151 Arsenic Arsenic affects the expression of IL2RB mRNAaffects expression 18414638
D001554 Benzene Benzene results in increased expression of IL2RB mRNAincreases expression 15929907
D019324 beta-Naphthoflavone [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of IL2RB mRNAaffects cotreatment|increases expression 18164116
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of IL2RB mRNAincreases expression 16239168
D002794 Choline Choline affects the expression of IL2RB mRNAaffects expression 17616785
C402665 CP 31398 CP 31398 results in increased expression of IL2RB mRNAincreases expression 15155752
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of IL2RB mRNAaffects cotreatment|increases expression 18164116
D004958 Estradiol [Progesterone co-treated with Estradiol] results in decreased expression of IL2RB mRNAaffects cotreatment|decreases expression 17404688
D006581 Hexachlorobenzene Hexachlorobenzene affects the expression of IL2RB mRNAaffects expression 15159207
C013592 mangiferin mangiferin results in decreased expression of IL2RB mRNAdecreases expression 15135318
D009151 Mustard Gas Mustard Gas results in increased expression of IL2RB mRNAincreases expression 15674844
C006253 pirinixic acid NCF1 protein promotes the reaction [pirinixic acid results in decreased expression of IL2RB mRNA]decreases expression|increases reaction 17950772
C006253 pirinixic acid pirinixic acid results in decreased expression of IL2RB mRNAdecreases expression 17950772
D011374 Progesterone [Progesterone co-treated with Estradiol] results in decreased expression of IL2RB mRNAaffects cotreatment|decreases expression 17404688
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D055371 Acute Lung Injury pirinixic acid 3.1518653653
MESH:D000230 Adenocarcinoma Estradiol 2.1011473722
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 11.323712494
MESH:D000236 Adenoma beta-Naphthoflavone 11.3219389873
MESH:D000236 Adenoma Diethylnitrosamine 11.326695378 10737359
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 10.2616434500 19052882 18056438 19061943 17162532 17620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 10.2616434500
MESH:D018246 Adrenocortical Adenoma Arsenic 5.2817306315
MESH:D000707 Anaphylaxis mangiferin 5.5114669257 16536907
MESH:D000741 Anemia, Aplastic Benzene 4.3917661222 14761424 11369114
MESH:D020261 Arsenic Poisoning Arsenic 2.8712569548 18414634 16251483 16835338
MESH:D001172 Arthritis, Rheumatoid marker/mechanism 20453842
MESH:D001249 Asthma Mustard Gas 2.7210378619
MESH:D050197 Atherosclerosis Arsenic 7.2512928151 19371607
MESH:D050197 Atherosclerosis mangiferin 7.2518450471
MESH:D001321 Autistic Disorder Choline 3.3516818868
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 5.0811289319 1440618
MESH:D001768 Blister Mustard Gas 5.2119167455
MESH:D001778 Blood Coagulation Disorders pirinixic acid 3.1719483382
MESH:D001855 Bone Marrow Diseases Benzene 5.2916183116
MESH:D001862 Bone Resorption mangiferin 4.949881647
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 5.4017868700
MESH:D001930 Brain Injuries Progesterone 4.3015665606 15845082 15380490
MESH:D001943 Breast Neoplasms Benzene 2.3811921183 17162533
MESH:D001943 Breast Neoplasms Diethylnitrosamine 2.3817474063
MESH:D001943 Breast Neoplasms Estradiol 2.3812948864 18497071 17289903 16675129 19861407 14630087 17018787 17261762
MESH:D001943 Breast Neoplasms Hexachlorobenzene 2.3812709520 15061365
MESH:D001943 Breast Neoplasms Progesterone 2.3817614352 15562024 16175315
MESH:D001989 Bronchiolitis Obliterans Mustard Gas 5.2115286001
MESH:D029481 Bronchitis, Chronic Mustard Gas 5.0417687719 10378619
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.5116111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.8216124888 15673190 10355542 16227642 16097048 15721981 16050911 15700767 3786805 18705752 16011737 16192424
MESH:D002280 Carcinoma, Basal Cell Arsenic 3.6117687452 15504454
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 8.933581430 7296757
MESH:D006528 Carcinoma, Hepatocellular Arsenic 8.9316507464 17306315
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 8.9318788625
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 8.9318785209 16569478 16779866 19919837 20101231 18210153 20935162 16328049 18494052 17761372 17162532 20514400 20007298 18788625 17428255 17978847 16540662 20727157 19107877 19208518 21159647 17055752 11831363 18506893 18978308 10672840 20084675 16935385 19335982 18393292 19394651 19539802 3581430 17138121 16698587 20214788 19519916 16288022 19822196 3084413 16807293 17173139 19383236 16502159 20512989 19052882 16830150 19701751 20524982 19171122 18665156 16878318 18971187 16681979 19418558 20432363 18691550 10737359 18056438
MESH:D006528 Carcinoma, Hepatocellular Estradiol 8.9316924424
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.697296757
MESH:D002294 Carcinoma, Squamous Cell Arsenic 2.7018922899 15504454 17687452
MESH:D002295 Carcinoma, Transitional Cell Arsenic 4.1018640142
MESH:D002318 Cardiovascular Diseases Arsenic 3.4715738583 17938729 19152805
MESH:D002340 Carotid Artery Diseases Arsenic 4.3316973168 18022660
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 11.307505956
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 11.3021159647 17174075 7505956 2727394
MESH:D002471 Cell Transformation, Neoplastic Estradiol 11.3018566989
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 3.7119052882
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 7.919022650 19486331
MESH:D002779 Cholestasis pirinixic acid 7.9119176532
MESH:D019465 Craniofacial Abnormalities Benzene 2.4415643154
MESH:D003457 Cryptosporidiosis mangiferin 5.9216547730
MESH:D003872 Dermatitis Benzene 4.8115902427
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.8418759878 2524372 12868966 11298694 8156756 11906362 14531868 8970840
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.4418249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.523621924 2952479
MESH:D002658 Developmental Disabilities Choline 4.6916818868
MESH:D003921 Diabetes Mellitus, Experimental mangiferin 4.6219028559 12093613
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 4.9120387270
MESH:D003924 Diabetes Mellitus, Type 2 mangiferin 4.919881663 11315760
MESH:D003928 Diabetic Nephropathies Estradiol 9.4119279558
MESH:D003928 Diabetic Nephropathies mangiferin 9.4119960420 19706694
MESH:D003929 Diabetic Neuropathies Progesterone 4.5317187935
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 6.2911289319 18289764 18648102 18692083 9022650 16192314 9653073 7440962 6679447 8291058 1440618 9328219 6482804
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 6.299327722 7440962 15998439 10915739 15968718 4309450 3786805 16177239 3732212 16227642 19336974 17522070 15027814 19085960 7179309 21278145 7120509 2869522 6884620 11566570 10092053 6623471
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 6.2919107877
MESH:D004487 Edema Mustard Gas 6.989260866 11402378 11428647 11428631
MESH:D004487 Edema pirinixic acid 6.9812083418
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 3.8217692515
MESH:D016889 Endometrial Neoplasms Estradiol 3.0011473722 18566989 19148513
MESH:D004715 Endometriosis Progesterone 3.7916134523
MESH:D004890 Erythema Mustard Gas 5.219357497
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 5.1816302075
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 2.113581430
MESH:D005234 Fatty Liver Carbon Tetrachloride 19.0961145 12631006 19224547 12795759 15959796 16045604 16239168 17595544
MESH:D005234 Fatty Liver Diethylnitrosamine 19.0921071580 20387270
MESH:D005234 Fatty Liver mangiferin 19.0915975614
MESH:D005234 Fatty Liver pirinixic acid 19.0920131406 19236843
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 5.086705139
MESH:D005355 Fibrosis Carbon Tetrachloride 3.5018705752
MESH:D005534 Foot Diseases Arsenic 5.626392382
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 4.077505956
MESH:D006331 Heart Diseases mangiferin 4.4112093613
MESH:D006333 Heart Failure pirinixic acid 2.5520558911
MESH:D006402 Hematologic Diseases Benzene 4.6916183116
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 9.356705139
MESH:D006505 Hepatitis Carbon Tetrachloride 9.3519900420 19110552
MESH:D006529 Hepatomegaly pirinixic acid 3.0419176532 16221962 19772884 18467677
MESH:D006558 Herpes Genitalis Estradiol 5.0915709030
MESH:D006561 Herpes Simplex mangiferin 5.0510715843
MESH:D019584 Hot Flashes Estradiol 3.8117088409
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.5816899240
MESH:D006943 Hyperglycemia pirinixic acid 3.2120558911
MESH:D006946 Hyperinsulinism mangiferin 5.0211315760 9881663
MESH:D017488 Hyperkeratosis, Epidermolytic Arsenic 4.4817050553
MESH:D006949 Hyperlipidemias mangiferin 4.8815975614
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.9815034207
MESH:D006967 Hypersensitivity mangiferin 4.7216536907
MESH:D006973 Hypertension Arsenic 5.7011953799 16076760 9931084
MESH:D006973 Hypertension Benzene 5.7017940673
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.1315338365
MESH:D006987 Hypesthesia Arsenic 5.6216093927
MESH:D007154 Immune System Diseases mangiferin 5.9216076520
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 4.4415869954
MESH:D007249 Inflammation Diethylnitrosamine 12.1918785209
MESH:D007249 Inflammation mangiferin 12.1915222974
MESH:D007249 Inflammation Mustard Gas 12.199260866 11428631 11428620 16001271 9357497 11428647 8975870 11402378 17524151
MESH:D007249 Inflammation Progesterone 12.1915869954
MESH:D007333 Insulin Resistance Estradiol 12.5616393666 16627594
MESH:D007333 Insulin Resistance mangiferin 12.5611315760
MESH:D007333 Insulin Resistance pirinixic acid 12.5616306350
MESH:D007511 Ischemia mangiferin 5.3116806951
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 5.089022650 8074119
MESH:D007642 Keratosis Arsenic 5.0412749816 16930632
MESH:D007674 Kidney Diseases Estradiol 6.5815618244
MESH:D007674 Kidney Diseases mangiferin 6.5812093613
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 7.446582329
MESH:D007680 Kidney Neoplasms Estradiol 7.4415610895
MESH:D007859 Learning Disorders mangiferin 4.9919182383
MESH:D007938 Leukemia Benzene 3.4017119257 15935818 18335105 14694614
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive mangiferin 4.6315498116
MESH:D007951 Leukemia, Myeloid Benzene 4.3517506065
MESH:D015470 Leukemia, Myeloid, Acute Benzene 2.7019478238
MESH:D015473 Leukemia, Promyelocytic, Acute Arsenic 3.5717339181
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 6.6611408273 17174718 16943688 21278145 17334410 16239168 11903743 16221502 17157831
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 6.6618522880 18407596 18665156 19638242 20032147
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.2115034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 3.4618395095 12666154 18263696 14748882 16011737 17805973 16097048 17761835 11481614 15925388 12586293 16136751 18205269 18277467 20821823 15673190 14724832 15338365 14716833 12898905 15650968 18251166 15893842 16638106 15052691 18472094 16033810 12546737 15996030 17823541 17900296 18054572 12609069 15818738 15959796 17714472 18429990 14716496 18279442 17922224 12958196 12649538 17565644 17481882 15362042 15370692 17944888 18395914 18339082 15730626 18317297 12632514 10355542 18006644 17976157 17869086 18705752 16248980 15057751 15931870 16116963 18412020 15123356 18472332 16027843 17708605 18420326 12445418 17721639 18210741 18481824 16015684 18166357 12389079 12741479 18376398 18187930 14512876 17640975 14620537 13678700 17557913 12667390 17698563 18156304 17766677 16192424 17525996 17631135 15876570 12632512 12445421 18418968
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 3.4614716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 3.4615474484
MESH:D008107 Liver Diseases Arsenic 6.6411134558
MESH:D008107 Liver Diseases Carbon Tetrachloride 6.6417285989 15830285 15720792 16964402 16246199
MESH:D008107 Liver Diseases Diethylnitrosamine 6.6417034775
MESH:D017093 Liver Failure Carbon Tetrachloride 4.2115123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 3.7216899240 14706259
MESH:D008113 Liver Neoplasms Arsenic 14.3716368122
MESH:D008113 Liver Neoplasms beta-Naphthoflavone 14.3719389873 21295105
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 14.3719294768
MESH:D008113 Liver Neoplasms Diethylnitrosamine 14.3719255062 12112319 19073162 12771043 16942905 15175105 19256749 19254457 9163691 20101389 19850985 20452335 19833225 19812893 20434301 20118626 20583210 19638242 19427195 18978307 20405173 21278145 20492335 19426721 10737359 20137499 21167192 18648771 15885732 18977376 19996281 19294768 21047994 19690152 2422723 19499222 19551842 18644402 19090486 18754104 20501860 2862719 19642983 21071580
MESH:D008113 Liver Neoplasms pirinixic acid 14.3720007298 15890375 16377806
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 23.646587162 598648 3712494 1399818
MESH:D008114 Liver Neoplasms, Experimental Benzene 23.6412562636
MESH:D008114 Liver Neoplasms, Experimental beta-Naphthoflavone 23.6418164116
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 23.6412014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 23.6418253720 19539802 19519916 19009564 18093689 16267830 17854601 18544905 18164116 18079962 21159647 17174075 18282651 18775883 19126423 9362446 16842330 19004024 17942915 2563599 18308698 3124819
MESH:D008114 Liver Neoplasms, Experimental Hexachlorobenzene 23.641423854
MESH:D008171 Lung Diseases Mustard Gas 3.4718161513 18702808
MESH:D017563 Lung Diseases, Interstitial Benzene 4.8714698565
MESH:D008175 Lung Neoplasms Arsenic 6.6717306315 19168569 17976673
MESH:D008175 Lung Neoplasms Benzene 6.6712562636
MESH:D008175 Lung Neoplasms Diethylnitrosamine 6.6721163286 20970405 20512841 6695378
MESH:D008175 Lung Neoplasms mangiferin 6.6718816296 18569708 18520028
MESH:D008175 Lung Neoplasms Mustard Gas 6.673148597 8781369
MESH:D008223 Lymphoma Benzene 3.7517584886 17119257
MESH:D015674 Mammary Neoplasms, Animal Benzene 4.4912562636
MESH:D008325 Mammary Neoplasms, Experimental Benzene 10.1711921183
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 10.1711807958 16891317 17203775 11408345
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 10.1717203775 11408345
MESH:D020149 Manganese Poisoning Estradiol 4.5519453300
MESH:D008569 Memory Disorders mangiferin 4.9719182383
MESH:D009101 Multiple Myeloma Benzene 3.6817119195
MESH:D009135 Muscular Diseases pirinixic acid 3.5516239165
MESH:D009203 Myocardial Infarction mangiferin 6.0816538859 19172585 17052832 16584858 16697266
MESH:D009203 Myocardial Infarction pirinixic acid 6.0819151258
MESH:D017202 Myocardial Ischemia Arsenic 4.0015371236
MESH:D015428 Myocardial Reperfusion Injury Estradiol 8.3216810080
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 8.3216411023
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 5.743581430
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 5.743581430 9029167
MESH:D009369 Neoplasms pirinixic acid 1.9617405874
MESH:D009389 Neovascularization, Pathologic Estradiol 3.7817289903
MESH:D009410 Nerve Degeneration mangiferin 4.6317433543
MESH:D009421 Nervous System Malformations Estradiol 3.6916427766 11399458
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 12.366679447
MESH:D009436 Neural Tube Defects Arsenic 12.3616620997
MESH:D009436 Neural Tube Defects Benzene 12.3615643154
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 3.3620387270
MESH:D020078 Neurogenic Inflammation Arsenic 4.4117056641
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 5.1820387270
MESH:D009503 Neutropenia Mustard Gas 4.0016761898 7688884
MESH:D009765 Obesity pirinixic acid 1.8220558911
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 9.254026338 6482804
MESH:D009784 Occupational Diseases Benzene 9.2515935809 15576619 15727169 17119257 16737584 17479406 15913788 17178637 15612468
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 5.083988306
MESH:D010051 Ovarian Neoplasms Arsenic 11.4217306315
MESH:D010051 Ovarian Neoplasms Benzene 11.4212562636
MESH:D010051 Ovarian Neoplasms Estradiol 11.4219401270
MESH:D010051 Ovarian Neoplasms Progesterone 11.4217393432 16525653
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 2.4316540662
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.527296757
MESH:D010300 Parkinson Disease mangiferin 3.7217433543
MESH:D010518 Periodontitis mangiferin 5.6719026997
MESH:D010523 Peripheral Nervous System Diseases Arsenic 4.2116093927
MESH:D016491 Peripheral Vascular Diseases Arsenic 5.0415371236 6392382 16905509
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.536228378
MESH:D011041 Poisoning Mustard Gas 3.8315727166
MESH:D017119 Porphyria Cutanea Tarda Hexachlorobenzene 5.249918132
MESH:D011230 Precancerous Conditions Diethylnitrosamine 3.582563599
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.9120887781
MESH:D011471 Prostatic Neoplasms AGN 194204 2.7416000583
MESH:D011471 Prostatic Neoplasms Arsenic 2.7416140617
MESH:D011471 Prostatic Neoplasms Estradiol 2.7416740699
MESH:D011507 Proteinuria Arsenic 4.0421343184
MESH:D011537 Pruritus Mustard Gas 4.1418058305
MESH:D011658 Pulmonary Fibrosis Mustard Gas 2.9417620002 17894541 10334151 17266442 17720292
MESH:D011833 Radiation Injuries, Experimental mangiferin 6.4715830843
MESH:D015427 Reperfusion Injury pirinixic acid 2.4019058328
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.393692021
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.8618045962
MESH:D012772 Shock, Septic mangiferin 5.2915177305
MESH:D012871 Skin Diseases Arsenic 5.1616759981 19834688 17050553 6392382 16702368 17453740 15952646 17548696 16353154 18709164 17938729
MESH:D012871 Skin Diseases Mustard Gas 5.1615451306 12880345 16961503
MESH:D012878 Skin Neoplasms Arsenic 3.0215504454 17976673 19538983 17029826 17050553 16251483
MESH:D013119 Spinal Cord Injuries Progesterone 4.3316503802 15862959
MESH:D013274 Stomach Neoplasms Benzene 2.6512562636
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 2.6518456281
MESH:D013276 Stomach Ulcer mangiferin 4.3017918041
MESH:D013953 Thymus Neoplasms Benzene 5.0110850423
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 7.196582329 1399818 6587162 3712494 7505956
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 7.197505956
MESH:D013978 Tibial Fractures Estradiol 4.7519048282
MESH:D014235 Trichinellosis mangiferin 6.1214669257
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 5.248074119
MESH:D001749 Urinary Bladder Neoplasms Arsenic 5.2419322015 17306315 17976673 15987713 11144890 18640142 19429237
MESH:D014594 Uterine Neoplasms Benzene 4.3712562636
MESH:D014652 Vascular Diseases Arsenic 4.7917056641
Pathway ID Pathway Name
KEGG:04060 Cytokine-cytokine receptor interaction
KEGG:04144 Endocytosis
KEGG:04630 Jak-STAT signaling pathway
KEGG:05162 Measles
REACT:6900 Signaling in Immune system
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA29829
    • No data
    Releated disease ID Related disease Name
    PA443434Arthritis, Rheumatoid
    PA443434Arthritis, Rheumatoid
    No data
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB00004 agonist Denileukin diftitox Antineoplastic Agents
    DB00041 modulator Aldesleukin Antineoplastic Agents
    DB00074 antibody Basiliximab Immunomodulatory Agents;Immunosuppressive Agents
    DB00111 antibody Daclizumab Immunomodulatory Agents;Immunosuppressive Agents
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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