AutismKB 2.0

Annotation Detail for DPPA3


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Basic Information Top
Gene Symbol:DPPA3 ( STELLA )
Gene Full Name: developmental pluripotency associated 3
Band: 12p13.31
Quick LinksEntrez ID:359787; OMIM: 608408; Uniprot ID:DPPA3_HUMAN; ENSEMBL ID: ENSG00000187569; HGNC ID: 19199
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of DPPA3 mRNAaffects expression 17562736
D002087 Butyrates Butyrates results in increased expression of DPPA3 proteinincreases expression 20201064
D014212 Tretinoin Tretinoin results in decreased expression of DPPA3 mRNAdecreases expression 16168501
D014212 Tretinoin NR6A1 protein affects the reaction [Tretinoin results in decreased expression of DPPA3 mRNA]affects reaction|decreases expression 16166633
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000505 Alopecia Tretinoin 3.9815955085
MESH:D000799 Angioedema Acetaminophen 4.7110982225
MESH:D001169 Arthritis, Experimental Tretinoin 3.3216412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.3416292516
MESH:D001249 Asthma Tretinoin 2.4416456186
MESH:D001321 Autistic Disorder Acetaminophen 1.3918445737
MESH:D001471 Barrett Esophagus Tretinoin 4.9916935849
MESH:D001778 Blood Coagulation Disorders Tretinoin 4.0916197459 16206674
MESH:D001943 Breast Neoplasms Tretinoin 2.2316443354 16873071 16166294
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 5.3316813970
MESH:D018236 Carcinoma, Embryonal Tretinoin 6.0316168501
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 3.023084413
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 3.021917145
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 2.3816051514 16096774
MESH:D002386 Cataract Acetaminophen 7.9910977129
MESH:D002386 Cataract Tretinoin 7.9917460283
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 5.3316129372
MESH:D002822 Choriocarcinoma Tretinoin 6.0316461808
MESH:D002972 Cleft Palate Tretinoin 2.819407595
MESH:D003092 Colitis Tretinoin 4.3517035595
MESH:D003110 Colonic Neoplasms Butyrates 3.1315936596
MESH:D019465 Craniofacial Abnormalities Tretinoin 1.839664655 10589399 14991402 17551590 9211117 8800419 9224671 9142499 9125849 16925845
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 1.6814550746 10915739 10774834 16177239 12153990 11287661 12540782 12958197 12392966 17906064 10663392 19420014 18713872 11834606 16393943 11421492 15619225 15968718 17562736 19164858 19370779 16227642 16485898 2444490 11461765 16109766 18071297 14986274 11529661 19085960 14725611 19923254 16781746 19416960 11743745 12594235 12705907 17522070 11739529 19739265 16081117
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.9619426721
MESH:D004489 Edema, Cardiac Tretinoin 5.3318230668
MESH:D016889 Endometrial Neoplasms Tretinoin 3.3716569247
MESH:D005124 Eye Abnormalities Tretinoin 3.9016938888 9664655
MESH:D005355 Fibrosis Tretinoin 4.1617994277
MESH:D005756 Gastritis Acetaminophen 4.5416983495
MESH:D005909 Glioblastoma Tretinoin 3.2717312396
MESH:D006258 Head and Neck Neoplasms Tretinoin 3.4616096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 6.0316084493
MESH:D006330 Heart Defects, Congenital Tretinoin 3.099664655 14991402
MESH:D006930 Hyperalgesia Acetaminophen 8.8616870215
MESH:D006930 Hyperalgesia Tretinoin 8.8616870215
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 5.2216778211
MESH:D007410 Intestinal Diseases Tretinoin 4.4217994277
MESH:D007569 Jaw Abnormalities Tretinoin 4.3917551590 15992940
MESH:D007674 Kidney Diseases Acetaminophen 2.4212587719 15629191
MESH:D007938 Leukemia Tretinoin 2.9517143497
MESH:D007951 Leukemia, Myeloid Tretinoin 4.1819285840 16482212 16932348
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 2.1317596541 16294345 19850784
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 3.4219225113 17368321 16891316 16331271 17649720 19075265 19029980 17361223 17217047 9834237 16140955 17107899 12679006 17294898 17506722 15748426 17301526 19035177 16935935 19642359 17339181 17712046 16766008 16823087 16788101
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.629224671
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 1.8116248980 18397230
MESH:D008107 Liver Diseases Acetaminophen 1.7119014921 16611625 19784758 11587558 12969438 12587719 19460945 16610002
MESH:D017114 Liver Failure, Acute Acetaminophen 3.6817185352 16871587
MESH:D008527 Medulloblastoma Tretinoin 2.9217453147
MESH:D008545 Melanoma Tretinoin 1.9916752155
MESH:D008546 Melanoma, Experimental Acetaminophen 4.2219513568
MESH:D008591 Meningomyelocele Tretinoin 5.0816940565
MESH:D009190 Myelodysplastic Syndromes Tretinoin 3.3017596541
MESH:D009369 Neoplasms Tretinoin 2.5916946489 16594593
MESH:D009373 Neoplasms, Germ Cell and Embryonal marker/mechanism 16168501
MESH:D009421 Nervous System Malformations Tretinoin 4.369125849
MESH:D009436 Neural Tube Defects Tretinoin 3.329142499
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.2618514411
MESH:D010051 Ovarian Neoplasms Tretinoin 2.4516936753
MESH:D010146 Pain Acetaminophen 7.8916870215
MESH:D010146 Pain Tretinoin 7.8916870215
MESH:D010190 Pancreatic Neoplasms Tretinoin 2.5815976015
MESH:D011507 Proteinuria Tretinoin 4.1316636307
MESH:D011625 Pterygium Tretinoin 5.5416723453
MESH:D012208 Rhabdomyosarcoma Tretinoin 4.6316283617 16116481
MESH:D012878 Skin Neoplasms Tretinoin 2.7816467112
MESH:D013274 Stomach Neoplasms Tretinoin 1.8017261132
MESH:D013964 Thyroid Neoplasms Butyrates 8.7317967635
MESH:D013964 Thyroid Neoplasms Tretinoin 8.7316026305 17045167
MESH:D014062 Tongue Neoplasms Tretinoin 4.2416051514
MESH:D014376 Tuberculosis Tretinoin 3.4716040207
MESH:D014581 Urticaria Acetaminophen 3.5010982225
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 4.1216129372
MESH:D014604 Uveal Neoplasms Tretinoin 5.4816752155
MESH:D014820 Vitiligo Tretinoin 4.6416761959
MESH:D009396 Wilms Tumor Tretinoin 4.3916287080
No data
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Syndromic Genes

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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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