AutismKB 2.0

Annotation Detail for ITIH3


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Basic Information Top
Gene Symbol:ITIH3 ( H3P )
Gene Full Name: inter-alpha (globulin) inhibitor H3
Band: 3p21.1
Quick LinksEntrez ID:3699; OMIM: 146650; Uniprot ID:ITIH3_HUMAN; ENSEMBL ID: ENSG00000162267; HGNC ID: 6168
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
Desease IDDesease Name
2066Lung cancer
2237Neoplasm metastasis
Desease Name
CARDIOVASCULAR
myocardial infarct
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C028474 1,4-bis(2-(3,5-dichloropyridyloxy))benzene 1,4-bis(2-(3,5-dichloropyridyloxy))benzene affects the expression of ITIH3 mRNAaffects expression 18281256
C014211 2,3,7,8-tetrachlorodibenzofuran 2,3,7,8-tetrachlorodibenzofuran affects the expression of ITIH3 mRNAaffects expression 18343893
C063002 2,3-dimethoxy-1,4-naphthoquinone 2,3-dimethoxy-1,4-naphthoquinone results in decreased expression of ITIH3 mRNAdecreases expression 17547211
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of ITIH3 mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of ITIH3 mRNAaffects expression 17562736
D000643 Ammonium Chloride Ammonium Chloride affects the expression of ITIH3 mRNAaffects expression 16483693
D000965 Antimony Antimony results in decreased expression of ITIH3 mRNAdecreases expression 17547211
D000966 Antimony Potassium Tartrate Antimony Potassium Tartrate results in decreased expression of ITIH3 mRNAdecreases expression 17547211
C095105 bexarotene bexarotene results in decreased expression of ITIH3 mRNAdecreases expression 16648578
D002101 Cacodylic Acid Cacodylic Acid results in increased expression of ITIH3 mRNAincreases expression 17481689
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of ITIH3 mRNAaffects expression 12734012
D002857 Chromium Chromium results in decreased expression of ITIH3 mRNAdecreases expression 17547211
D016572 Cyclosporine Cyclosporine results in increased expression of ITIH3 mRNAincreases expression 20106945
D004052 Diethylnitrosamine Diethylnitrosamine results in decreased expression of ITIH3 mRNAdecreases expression 20360939
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of ITIH3 mRNAaffects expression 17555576
D007657 Ketone Bodies Ketone Bodies results in increased expression of ITIH3 mRNAincreases expression 16807920
D008628 Mercury Mercury results in decreased expression of ITIH3 mRNAdecreases expression 17547211
C020300 monomethylarsonic acid monomethylarsonic acid results in increased expression of ITIH3 mRNAincreases expression 17481689
C006253 pirinixic acid pirinixic acid results in increased expression of ITIH3 mRNAincreases expression 18445702
D011192 Potassium Dichromate Potassium Dichromate results in decreased expression of ITIH3 mRNAdecreases expression 17547211
C045950 propiconazole propiconazole results in decreased expression of ITIH3 mRNAdecreases expression 19363144
C017947 sodium arsenite sodium arsenite results in increased expression of ITIH3 mRNAincreases expression 16014739
D013629 Tamoxifen Tamoxifen affects the expression of ITIH3 mRNAaffects expression 17555576
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin affects the expression of ITIH3 mRNAaffects expression 18343893
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of ITIH3 mRNAincreases expression 16267337
C052920 trimethylarsine oxide trimethylarsine oxide results in increased expression of ITIH3 mRNAincreases expression 17481689
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.3514745880
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.6615322242 14514962 11752688
MESH:D000138 Acidosis Ammonium Chloride 3.3718287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.7517505938
MESH:D055371 Acute Lung Injury pirinixic acid 2.9418653653
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.7714692618
MESH:D000236 Adenoma Diethylnitrosamine 2.746695378 10737359
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 16.1618056438 17620307 17162532 19052882 16434500 19061943
MESH:D018248 Adenoma, Liver Cell pirinixic acid 16.1616434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 16.1616835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.5115276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.7117306315 16712894
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.7811748828
MESH:D000799 Angioedema Acetaminophen 3.6510982225
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.2811256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.5515885639
MESH:D001321 Autistic Disorder Acetaminophen 2.1418445737
MESH:D001321 Autistic Disorder Mercury 2.1417497416
MESH:D001327 Autoimmune Diseases Mercury 4.6816634805
MESH:D001778 Blood Coagulation Disorders pirinixic acid 8.1919483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 8.1912125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.6015340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.6415746008
MESH:D001943 Breast Neoplasms bexarotene 2.8816344269 16818667
MESH:D001943 Breast Neoplasms Cacodylic Acid 2.8817474063
MESH:D001943 Breast Neoplasms Chromium 2.8815986119
MESH:D001943 Breast Neoplasms Diethylnitrosamine 2.8817474063
MESH:D001943 Breast Neoplasms Tamoxifen 2.8819244106 18629630 19200415 18984771 20390343 19189210 17440819 19221464 19066611 18351453 19487384 16202921 17049068 20544844 19288272 15565566 21152245 19115204 19103187 19084267 18821012 19011961 18997820 17893378 17261762 18815881 16273361 20005174 21138602 19155303 19410462 20135344 20065188 19142967 19059307 15668708 20859285 11161223 16873071 19189212 16818667 18855134 18425577 19289846 17242785
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.8820435547
MESH:D001991 Bronchitis Antimony 5.948768112
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.5916011737 16124888 16097048 15721981 3786805 15700767 15673190 16227642 10355542 18705752 16192424 16050911
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.6516835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.3219066611
MESH:D006528 Carcinoma, Hepatocellular marker/mechanism 19363144
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 10.9716705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 10.973084413
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 10.9718788625
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 10.9719919837 18506893 16328049 20007298 20514400 18691550 16288022 19107877 10672840 19418558 17173139 11831363 3084413 19822196 18393292 17761372 16569478 19383236 19539802 18978308 17055752 20101231 17978847 20935162 19208518 21159647 16935385 18056438 19171122 3581430 17138121 16830150 19052882 20512989 18210153 19394651 20214788 16681979 19701751 19335982 20727157 16698587 16878318 16779866 16502159 20084675 18788625 20432363 16540662 18494052 20524982 18665156 16807293 10737359 17162532 17428255 18785209 18971187 19519916
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 10.9716507464 17306315 15276417
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 10.9716924424
MESH:D002289 Carcinoma, Non-Small-Cell Lung bexarotene 3.1616247446
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 2.3318572023
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.4517572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.2616120746 18670907 18850075
MESH:D002311 Cardiomyopathy, Dilated Antimony 6.3210334427
MESH:D002311 Cardiomyopathy, Dilated Mercury 6.3210334427
MESH:D002386 Cataract Acetaminophen 2.4710977129
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 14.956135515
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 14.9512371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 14.9517174075 2727394 21159647 7505956
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 14.9519524636 20056578
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 8.7919052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 8.7916835633
MESH:D002779 Cholestasis Cyclosporine 12.5319486331
MESH:D002779 Cholestasis Ethinyl Estradiol 12.5317681005 17333356 16919318 11677210 15861022 16105132 17110522
MESH:D002779 Cholestasis pirinixic acid 12.5319176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.0312621046 15340226 15668235 8697196 16354765
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.9014669216 17141729
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 1.2510048152 15322242 20055451
MESH:D003490 Cyanosis 2,6-dinitrotoluene 3.8318551238
MESH:D003711 Demyelinating Diseases Tamoxifen 4.1719031437
MESH:D017449 Dermatitis, Allergic Contact Mercury 7.1216823706
MESH:D017449 Dermatitis, Allergic Contact Potassium Dichromate 7.1216823706
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3418249437
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 4.0620387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.0617107852
MESH:D003928 Diabetic Nephropathies Tamoxifen 3.3219279558
MESH:D004283 Dog Diseases Antimony 5.4612019027
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 11.3818551238 21346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 11.3811739529 11421492 16485898 10915739 11743745 14986274 19420014 18071297 12153990 16109766 18713872 11461765 12540782 19739265 10663392 16081117 19164858 19085960 16393943 12958197 12594235 12392966 17562736 19416960 11529661 15968718 19923254 16781746 2444490 14725611 19370779 16227642 14550746 12705907 10774834 11834606 15619225 17906064 17522070 16177239 11287661
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 11.3810092053 2869522 7120509 17522070 15027814 9327722 3786805 15968718 7179309 4309450 19336974 7440962 11566570 16227642 15998439 21278145 3732212 19085960 6884620 10915739 6623471 16177239
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 11.3819107877
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 11.3820420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.9119426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.6211462148
MESH:D004487 Edema pirinixic acid 5.9712083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 5.9711000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.7116714409 15322242 18230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 8.3312538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 8.3319031437
MESH:D016889 Endometrial Neoplasms Tamoxifen 2.9216202921 20544844 17893378 19155303
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.8610568697 9294722
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.9216302075
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.8711564622
MESH:D005234 Fatty Liver Carbon Tetrachloride 28.4615959796 17595544 12795759 16045604 12631006 16239168 61145 19224547
MESH:D005234 Fatty Liver Cyclosporine 28.4619224547
MESH:D005234 Fatty Liver Diethylnitrosamine 28.4620387270 21071580
MESH:D005234 Fatty Liver Ethinyl Estradiol 28.4615345470
MESH:D005234 Fatty Liver pirinixic acid 28.4620131406 19236843
MESH:D005234 Fatty Liver Tamoxifen 28.4619224547 14986274
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.1216709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.2711858732
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.3414745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 3.9919069698
MESH:D005355 Fibrosis Carbon Tetrachloride 13.6118705752
MESH:D005355 Fibrosis Cyclosporine 13.6112639820 12168785
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 13.6120067830
MESH:D005756 Gastritis Acetaminophen 3.4816983495
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.4916452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.038708960
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.4010696789
MESH:D006330 Heart Defects, Congenital 2,3,7,8-tetrachlorodibenzofuran 6.6511294989
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.6511294989 10048152
MESH:D006333 Heart Failure pirinixic acid 2.4220558911
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.2315720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.1611000095
MESH:D006505 Hepatitis Carbon Tetrachloride 3.4119900420 19110552
MESH:D006529 Hepatomegaly 1,4-bis(2-(3,5-dichloropyridyloxy))benzene 19.2216109766
MESH:D006529 Hepatomegaly pirinixic acid 19.2219176532 16221962 18467677 19772884
MESH:D006529 Hepatomegaly propiconazole 19.2217178689 17178688
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 19.2215340226 12621046 16120746
MESH:D006689 Hodgkin Disease sodium arsenite 3.0012676792
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.8516354765 8697196 16959395 15340226 18606429
MESH:D006930 Hyperalgesia Acetaminophen 2.5516870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.3416899240
MESH:D006943 Hyperglycemia pirinixic acid 3.0220558911
MESH:D006973 Hypertension Cyclosporine 4.7010903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 4.7018670907 18850075
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.9015338365
MESH:D007021 Hypospadias Ethinyl Estradiol 3.6216569931 16945680
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.2812013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 6.2217937319
MESH:D007248 Infertility, Male sodium arsenite 6.2212646999 15346721
MESH:D007249 Inflammation Diethylnitrosamine 7.6918785209
MESH:D007249 Inflammation Tamoxifen 7.6919457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 7.6912878042 12200463
MESH:D007333 Insulin Resistance pirinixic acid 2.5116306350
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.1616580747
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.2515604871
MESH:D007674 Kidney Diseases Acetaminophen 22.4712587719 15629191
MESH:D007674 Kidney Diseases Chromium 22.4717934191
MESH:D007674 Kidney Diseases Cyclosporine 22.4710903974 8314463 18776723
MESH:D007674 Kidney Diseases Mercury 22.4717934191
MESH:D007674 Kidney Diseases Potassium Dichromate 22.4719665454
MESH:D007674 Kidney Diseases sodium arsenite 22.4720008137
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 11.4816705839
MESH:D007680 Kidney Neoplasms Cyclosporine 11.4812371664
MESH:D007680 Kidney Neoplasms Tamoxifen 11.4818625569
MESH:D007896 Leishmaniasis Antimony 4.6515220340 12019027 21182181 21063981 10953559
MESH:D016773 Leishmaniasis, Cutaneous Antimony 4.518889330 11475954 19141829
MESH:D007897 Leishmaniasis, Mucocutaneous Antimony 5.3010651420 11370249 9643325 10881086 7854095
MESH:D007898 Leishmaniasis, Visceral Antimony 8.2511105143 7554475 8142506 1899875 7854095 20495762 7875148
MESH:D007898 Leishmaniasis, Visceral Antimony Potassium Tartrate 8.2512707265
MESH:D015473 Leukemia, Promyelocytic, Acute Antimony Potassium Tartrate 4.399834237
MESH:D008064 Lipidoses Tamoxifen 3.0215342952 17567588
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 6.2621278145 11408273 11903743 16943688 16239168 17157831 16221502 17334410 17174718
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 6.2618407596 20032147 18522880 19638242 18665156
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 4.7212389079 15057751 15925388 20821823 18054572 13678700 15931870 16011737 17698563 15123356 17922224 17640975 16638106 17721639 12445418 18006644 15818738 17944888 18210741 18418968 17714472 12632512 15673190 15370692 18277467 11481614 17823541 15052691 17761835 17766677 15730626 18420326 18472094 12586293 14716496 12609069 16015684 12958196 12546737 18481824 14748882 15876570 12741479 17565644 12632514 18395095 12898905 16033810 17557913 16192424 17708605 14724832 18472332 17631135 17869086 17976157 17481882 12445421 17805973 15893842 18412020 17900296 15338365 18205269 12649538 10355542 12666154 15996030 18376398 17525996 18251166 18279442 16136751 12667390 18395914 18156304 16248980 18263696 14512876 18166357 18429990 16116963 18705752 15650968 18339082 16027843 15959796 14620537 18317297 15362042 18187930 16097048 14716833
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 4.7215474484
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 4.7218564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 4.7212878042
MESH:D008107 Liver Diseases Acetaminophen 9.0019784758 16610002 19460945 16611625 12969438 11587558 19014921 12587719
MESH:D008107 Liver Diseases Carbon Tetrachloride 9.0016964402 15720792 17285989 15830285 16246199
MESH:D008107 Liver Diseases Diethylnitrosamine 9.0017034775
MESH:D008107 Liver Diseases propiconazole 9.0019363144
MESH:D017093 Liver Failure Carbon Tetrachloride 3.9715123358
MESH:D017114 Liver Failure, Acute Acetaminophen 8.8516871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 8.8516899240 14706259
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 24.707678174
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 24.7019294768
MESH:D008113 Liver Neoplasms Diethylnitrosamine 24.7019551842 18648771 19427195 12771043 2422723 12112319 2862719 18644402 15885732 20137499 21167192 20101389 19850985 19254457 20434301 15175105 21071580 19294768 19073162 18977376 20118626 19255062 20583210 19426721 20492335 19690152 19642983 18754104 19812893 20452335 18978307 21278145 19996281 19638242 19256749 19499222 19090486 10737359 9163691 20405173 21047994 20501860 16942905 19833225
MESH:D008113 Liver Neoplasms pirinixic acid 24.7020007298 15890375 16377806
MESH:D008113 Liver Neoplasms propiconazole 24.7019028983
MESH:D008113 Liver Neoplasms sodium arsenite 24.7015276417 16712894
MESH:D008113 Liver Neoplasms Tamoxifen 24.7016684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 24.7016984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 17.402876784 2876786 6135515
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 17.4012014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 17.4018308698 18775883 16842330 18079962 3124819 16267830 17942915 19009564 19004024 19539802 18544905 17174075 18093689 18164116 2563599 18253720 17854601 18282651 21159647 9362446 19519916 19126423
MESH:D008114 Liver Neoplasms, Experimental propiconazole 17.4017178689
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 17.4012151625
MESH:D008171 Lung Diseases sodium arsenite 3.0519095001
MESH:D008175 Lung Neoplasms bexarotene 6.3417849452
MESH:D008175 Lung Neoplasms Diethylnitrosamine 6.3420512841 20970405 6695378 21163286
MESH:D008175 Lung Neoplasms sodium arsenite 6.3417306315 17077188 16712894 19931552 15276417
MESH:D008175 Lung Neoplasms Tamoxifen 6.3418625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 6.3419555203 11884234
MESH:D016410 Lymphoma, T-Cell, Cutaneous bexarotene 4.9611161223
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.5719428831
MESH:D008325 Mammary Neoplasms, Experimental bexarotene 5.8815591091 19196723 19196722
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 5.8819196722 14580682 19196723 11731420 16827153
MESH:D020149 Manganese Poisoning Tamoxifen 4.3519453300
MESH:D008545 Melanoma sodium arsenite 3.2119082730 16487513
MESH:D008545 Melanoma Tamoxifen 3.2112393984 19393235
MESH:D018328 Melanoma, Amelanotic Tamoxifen 3.9915990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.3819513568
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.5916801185
MESH:D009135 Muscular Diseases pirinixic acid 3.3216239165
MESH:D009203 Myocardial Infarction pirinixic acid 2.0719151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.8712213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.8016411023
MESH:D009336 Necrosis 2,6-dinitrotoluene 3.677678174 18551238
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 5.489029167 3581430
MESH:D009362 Neoplasm Metastasis Tamoxifen 5.4819393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.4519410462
MESH:D009369 Neoplasms pirinixic acid 4.6317405874
MESH:D009369 Neoplasms sodium arsenite 4.6311559025
MESH:D009374 Neoplasms, Experimental sodium arsenite 3.4820056578
MESH:D009376 Neoplasms, Hormone-Dependent bexarotene 10.2919196722
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 10.2919189210 19196722 19200415
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.2517954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.1219348381 18481113
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.0314600291
MESH:D009436 Neural Tube Defects sodium arsenite 3.0212854658
MESH:D019636 Neurodegenerative Diseases Acetaminophen 7.6618514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 7.6620387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.9220387270
MESH:D009765 Obesity pirinixic acid 1.7720558911
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 3.2616049721
MESH:D010051 Ovarian Neoplasms sodium arsenite 2.3817306315 15276417
MESH:D010146 Pain Acetaminophen 2.2416870215
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 2.3616540662
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.5111578682
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.0612520081
MESH:D010409 Penile Diseases Antimony 5.549643325
MESH:D010493 Pericarditis Antimony 5.9220465667
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.3718163543
MESH:D011230 Precancerous Conditions Cyclosporine 8.4112371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 8.412563599
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.0011118676 11222880 11896295 11399792
MESH:D011471 Prostatic Neoplasms sodium arsenite 3.3216039940
MESH:D011471 Prostatic Neoplasms Tamoxifen 3.3215067354
MESH:D011537 Pruritus Ethinyl Estradiol 3.1215861022 16919318
MESH:D011565 Psoriasis Cyclosporine 2.1616882103
MESH:D015427 Reperfusion Injury pirinixic acid 2.2919058328
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.6518990726
MESH:D012640 Seizures 2,6-dinitrotoluene 2.4118551238
MESH:D012871 Skin Diseases monomethylarsonic acid 3.9621378128
MESH:D012878 Skin Neoplasms sodium arsenite 5.3019524636 18572023
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.3016192470
MESH:D013088 Spermatocele Ethinyl Estradiol 10.9216709447
MESH:D013088 Spermatocele Tamoxifen 10.9216709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.8519457130
MESH:D016135 Spinal Dysraphism sodium arsenite 3.6512854658
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 1.7518456281
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.4411994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.9915669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.7112697716
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 2.847505956
MESH:D014352 Trypanosomiasis Antimony 5.7415220340
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 11.3716049721
MESH:D001749 Urinary Bladder Neoplasms Cacodylic Acid 11.3715537745
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 11.3711723127 16712894 17306315 16452187
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 11.378653321 16712894 17572228
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 4.1310091137
MESH:D014581 Urticaria Acetaminophen 2.8010982225
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 3.6011813266
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.1214692618
MESH:D014605 Uveitis Cyclosporine 3.791336536
MESH:D014652 Vascular Diseases sodium arsenite 4.2317056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.4012125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.3714671159 15869587
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.0615886252
MESH:D014985 Xerophthalmia Cyclosporine 4.2517120751
No data
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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