AutismKB 2.0

Annotation Detail for ITPKA


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Basic Information Top
Gene Symbol:ITPKA ( IP3-3KA,IP3KA )
Gene Full Name: inositol 1,4,5-trisphosphate 3-kinase A
Band: 15q15.1
Quick LinksEntrez ID:3706; OMIM: 147521; Uniprot ID:IP3KA_HUMAN; ENSEMBL ID: ENSG00000137825; HGNC ID: 6178
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Pathway IDPathway Name
PWY-6364D-myo-inositol (1,3,4)-trisphosphate biosynthesis
PWY-6358superpathway of D-myo-inositol (1,4,5)-trisphosphate metabolism
PWY-63621D-myo-inositol hexakisphosphate biosynthesis II (mammalian)
Pathway IDPathway Name
hsa00562Inositol phosphate metabolism
hsa04020Calcium signaling pathway
hsa01100Metabolic pathways
hsa04070Phosphatidylinositol signaling system
No data
No data
No data
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of ITPKA mRNAaffects expression 21346803
C472791 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid results in decreased expression of ITPKA mRNAdecreases expression 16788091
C026137 3-hydroxyacetanilide 3-hydroxyacetanilide results in decreased expression of ITPKA mRNAdecreases expression 18544908
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in decreased expression of ITPKA mRNAdecreases expression 18648102
D000082 Acetaminophen Acetaminophen affects the expression of ITPKA mRNAaffects expression 17562736
D000082 Acetaminophen Acetaminophen results in decreased expression of ITPKA mRNAdecreases expression 18544908
D000643 Ammonium Chloride Ammonium Chloride affects the expression of ITPKA mRNAaffects expression 16483693
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of ITPKA mRNAdecreases expression 20106945
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of ITPKA mRNAincreases expression 17805973
D016572 Cyclosporine Cyclosporine results in increased expression of ITPKA mRNAincreases expression 20106945
D026423 S-Nitroso-N-Acetylpenicillamine S-Nitroso-N-Acetylpenicillamine results in decreased expression of ITPKA mRNAdecreases expression 12102619
C006253 pirinixic acid pirinixic acid results in decreased expression of ITPKA mRNAdecreases expression 17426115
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of ITPKA mRNAdecreases expression 20106945
D014212 Tretinoin Tretinoin results in decreased expression of ITPKA mRNAdecreases expression 16788091
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.9614514962 15322242 11752688
MESH:D000138 Acidosis Ammonium Chloride 3.6818287403
MESH:D055371 Acute Lung Injury pirinixic acid 3.2018653653
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 2.0020127859 20464547
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 6.753712494
MESH:D000236 Adenoma Benzo(a)pyrene 6.756695378
MESH:D018248 Adenoma, Liver Cell pirinixic acid 10.3016434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 10.3016835633
MESH:D000505 Alopecia Tretinoin 3.6815955085
MESH:D000740 Anemia Tetrachlorodibenzodioxin 3.0211748828
MESH:D000799 Angioedema Acetaminophen 3.9810982225
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.1819183758
MESH:D001169 Arthritis, Experimental Tretinoin 3.1216412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.2816292516
MESH:D001249 Asthma Tretinoin 2.3616456186
MESH:D001321 Autistic Disorder Acetaminophen 1.4118445737
MESH:D001471 Barrett Esophagus Tretinoin 4.5016935849
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 5.151440618 11289319
MESH:D001778 Blood Coagulation Disorders pirinixic acid 15.7619483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 15.7612125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 15.7616206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.9215340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.8115746008
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 1.8020146248 17474063
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.8020435547
MESH:D001943 Breast Neoplasms Tretinoin 1.8016873071 16443354 16166294
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.7116813970
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.8815673190 16011737 16227642 16097048 15721981 10355542 15700767 16192424 18705752 16050911 3786805 16124888
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.8616835633
MESH:D018236 Carcinoma, Embryonal Tretinoin 5.2916168501
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 8.9916705839
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 8.997296757 3581430
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 8.993084413
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 8.9918788625
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 8.991917145
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.717296757
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 4.6420419170
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 4.6416096774 16051514
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.4118850075 16120746 18670907
MESH:D002386 Cataract Acetaminophen 7.3810977129
MESH:D002386 Cataract Tretinoin 7.3817460283
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 6.757505956
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 6.7512371664
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.7116129372
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.2316835633
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 13.7319486331 9022650
MESH:D002779 Cholestasis Cyclosporine 13.7319486331
MESH:D002779 Cholestasis pirinixic acid 13.7319176532
MESH:D002822 Choriocarcinoma Tretinoin 5.2916461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.8716354765 15340226 12621046 8697196 15668235
MESH:D002972 Cleft Palate Tretinoin 5.879407595
MESH:D003092 Colitis Tretinoin 3.8117035595
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.1317141729 14669216
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.4720055451 10048152 15322242
MESH:D019465 Craniofacial Abnormalities Tretinoin 2.479224671 10589399 9664655 17551590 14991402 16925845 8800419 9142499 9125849 9211117
MESH:D003490 Cyanosis 2,4-dinitrotoluene 4.1218551238
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.9012868966 8156756 11298694 18759878 11906362 2524372 14531868 8970840
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.4618249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.583621924 2952479
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.6817107852
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 12.2521346803 18551238
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 12.256482804 1440618 18289764 8291058 18692083 9653073 11289319 7440962 9328219 9022650 18648102 16192314 6679447
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 12.2511739529 15968718 18713872 14986274 14550746 19416960 11529661 11287661 10774834 10915739 11743745 18071297 12392966 11834606 19164858 16227642 16081117 17522070 19420014 11421492 12153990 14725611 17562736 16781746 10663392 19739265 19370779 11461765 16485898 12705907 2444490 17906064 19923254 16177239 15619225 12958197 12540782 19085960 16393943 16109766 12594235
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 12.2517522070 10092053 16227642 11566570 4309450 3786805 7440962 15998439 10915739 19336974 16177239 7179309 2869522 6884620 19085960 15027814 15968718 7120509 6623471 3732212 21278145 9327722
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 12.2520420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.2319426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.8211462148
MESH:D004487 Edema pirinixic acid 6.8112083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 6.8111000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 12.4016714409 15322242 18230668
MESH:D004489 Edema, Cardiac Tretinoin 12.4018230668
MESH:D016889 Endometrial Neoplasms Tretinoin 3.1616569247
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.1010568697 9294722
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 4.433581430
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 4.4316530937
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 9.0411564622
MESH:D005124 Eye Abnormalities Tretinoin 9.0416938888 9664655
MESH:D005234 Fatty Liver Carbon Tetrachloride 13.5316045604 12795759 61145 15959796 19224547 12631006 16239168 17595544
MESH:D005234 Fatty Liver Cyclosporine 13.5319224547
MESH:D005234 Fatty Liver pirinixic acid 13.5319236843 20131406
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.5611858732
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 5.156705139
MESH:D005355 Fibrosis Carbon Tetrachloride 22.0618705752
MESH:D005355 Fibrosis Cyclosporine 22.0612639820 12168785
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 22.0620067830
MESH:D005355 Fibrosis Tretinoin 22.0617994277
MESH:D005756 Gastritis Acetaminophen 3.8116983495
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.348708960
MESH:D005909 Glioblastoma Tretinoin 3.0517312396
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 4.127505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.7310696789
MESH:D006258 Head and Neck Neoplasms Tretinoin 3.2416096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 5.2916084493
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 11.3320471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 11.3311294989 10048152
MESH:D006330 Heart Defects, Congenital Tretinoin 11.3314991402 9664655
MESH:D006333 Heart Failure pirinixic acid 2.5820558911
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.5415720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.4211000095
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 9.546705139
MESH:D006505 Hepatitis Carbon Tetrachloride 9.5419900420 19110552
MESH:D006529 Hepatomegaly pirinixic acid 8.6116221962 19772884 19176532 18467677
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 8.6115340226 12621046 16120746
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.1815340226 16959395 8697196 16354765 18606429
MESH:D006930 Hyperalgesia Acetaminophen 7.8416870215
MESH:D006930 Hyperalgesia Tretinoin 7.8416870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.6516899240
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.6716778211
MESH:D006943 Hyperglycemia pirinixic acid 3.2620558911
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 4.0415034207
MESH:D006973 Hypertension Cyclosporine 5.0410903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 5.0418670907 18850075
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.1915338365
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 1.8912200463 12878042
MESH:D007333 Insulin Resistance pirinixic acid 2.6816306350
MESH:D007410 Intestinal Diseases Tretinoin 3.8717994277
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 5.159022650 8074119
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 10.2116580747
MESH:D007569 Jaw Abnormalities Tretinoin 10.2115992940 17551590
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.5815604871
MESH:D007674 Kidney Diseases Acetaminophen 5.9412587719 15629191
MESH:D007674 Kidney Diseases Cyclosporine 5.9418776723 10903974 8314463
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 12.7716705839
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 12.776582329
MESH:D007680 Kidney Neoplasms Cyclosporine 12.7712371664
MESH:D007938 Leukemia Tretinoin 2.8117143497
MESH:D007951 Leukemia, Myeloid Tretinoin 3.7816482212 19285840 16932348
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 2.0919850784 16294345 17596541
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 3.2017368321 17107899 15748426 17294898 17301526 16823087 16331271 17361223 19029980 17339181 16935935 16788101 17217047 17712046 12679006 16891316 16766008 19075265 19225113 17649720 17506722 19642359 16140955 19035177 9834237
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.369224671
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 2.8516943688 21278145 11408273 11903743 16221502 17157831 16239168 17334410 17174718
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.2415034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 4.9916011737 17944888 15362042 12666154 18279442 12389079 15123356 17714472 16116963 15925388 16027843 12649538 15959796 18412020 18187930 12898905 12958196 18251166 18429990 16638106 18156304 14716496 16192424 17557913 14716833 18277467 18263696 18395914 18418968 12445418 17640975 15730626 17525996 15931870 18317297 16136751 12445421 18705752 17976157 14512876 12667390 17708605 15876570 18481824 12741479 15818738 18395095 15370692 12609069 18376398 18339082 16248980 18420326 18054572 18205269 14620537 13678700 15338365 12586293 17805973 12632512 17761835 15052691 17823541 17631135 12632514 17565644 16015684 17766677 18472094 15650968 15057751 15996030 17698563 10355542 12546737 15893842 18472332 17721639 18006644 20821823 17869086 17900296 15673190 18166357 14748882 14724832 17922224 11481614 17481882 16033810 18210741 16097048
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 4.9915474484
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 4.9912878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 4.9916248980 18397230
MESH:D008107 Liver Diseases Acetaminophen 3.9619014921 12587719 19784758 11587558 19460945 16611625 12969438 16610002
MESH:D008107 Liver Diseases Carbon Tetrachloride 3.9617285989 15830285 16964402 16246199 15720792
MESH:D017093 Liver Failure Carbon Tetrachloride 4.2715123358
MESH:D017114 Liver Failure, Acute Acetaminophen 9.6716871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 9.6716899240 14706259
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 10.9020195826 21137059
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 10.9019294768
MESH:D008113 Liver Neoplasms pirinixic acid 10.9015890375 20007298 16377806
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 10.9016984957
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 10.07598648 1399818 3712494 6587162
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 10.0712014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 10.0712151625
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 2.2020135361 18569708 17053015 18816296 20064080 20464547 20869020 18520028 6695378
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 2.2019555203 11884234
MESH:D008527 Medulloblastoma Tretinoin 2.8117453147
MESH:D008545 Melanoma Tretinoin 1.9516752155
MESH:D008546 Melanoma, Experimental Acetaminophen 3.6719513568
MESH:D008591 Meningomyelocele Tretinoin 4.5316940565
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.9216801185
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.2516381670
MESH:D009135 Muscular Diseases pirinixic acid 3.6116239165
MESH:D009190 Myelodysplastic Syndromes Tretinoin 3.1217596541
MESH:D009203 Myocardial Infarction pirinixic acid 2.1719151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.0812213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 3.0116411023
MESH:D009336 Necrosis 2,4-dinitrotoluene 3.9718551238
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 2.503581430
MESH:D009369 Neoplasms Benzo(a)pyrene 8.4211141357
MESH:D009369 Neoplasms pirinixic acid 8.4217405874
MESH:D009369 Neoplasms Tretinoin 8.4216946489 16594593
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.5817954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.3618481113 19348381
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 9.8314600291
MESH:D009421 Nervous System Malformations Tretinoin 9.839125849
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 7.406679447
MESH:D009436 Neural Tube Defects Tretinoin 7.409142499
MESH:D019636 Neurodegenerative Diseases Acetaminophen 2.9418514411
MESH:D009765 Obesity pirinixic acid 1.8320558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 9.1416049721 12819281
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 9.146482804 4026338
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 5.153988306
MESH:D010051 Ovarian Neoplasms Tretinoin 2.3716936753
MESH:D010146 Pain Acetaminophen 6.8116870215
MESH:D010146 Pain Tretinoin 6.8116870215
MESH:D010190 Pancreatic Neoplasms Tretinoin 2.4915976015
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.597296757
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.3812520081
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.606228378
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.6518163543
MESH:D011230 Precancerous Conditions Cyclosporine 3.2912371664
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.3111118676 11399792 11896295 11222880
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.9617292933
MESH:D011507 Proteinuria Tretinoin 3.6916636307
MESH:D011565 Psoriasis Cyclosporine 2.2516882103
MESH:D011625 Pterygium Tretinoin 4.9116723453
MESH:D015427 Reperfusion Injury pirinixic acid 2.4219058328
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.9318990726
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.433692021
MESH:D012208 Rhabdomyosarcoma Tretinoin 4.1916116481 16283617
MESH:D012640 Seizures 2,4-dinitrotoluene 2.5818551238
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 9.6010029692 19755658
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 9.6016192470
MESH:D012878 Skin Neoplasms Tretinoin 9.6016467112
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 2.3620155912 2093021
MESH:D013274 Stomach Neoplasms Tretinoin 2.3617261132
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 4.0412697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 7.347505956 3712494 1399818 6582329 6587162
MESH:D013964 Thyroid Neoplasms Tretinoin 7.3417045167 16026305
MESH:D014062 Tongue Neoplasms Tretinoin 3.8616051514
MESH:D014376 Tuberculosis Tretinoin 3.2716040207
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 8.4416049721
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 8.448074119
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 8.4417053015
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 4.4310091137
MESH:D014581 Urticaria Acetaminophen 3.0610982225
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 3.7516129372
MESH:D014604 Uveal Neoplasms Tretinoin 4.7416752155
MESH:D014605 Uveitis Cyclosporine 4.121336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.7312125929
MESH:D014820 Vitiligo Tretinoin 4.1516761959
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.3815886252
MESH:D009396 Wilms Tumor Tretinoin 4.0416287080
MESH:D014985 Xerophthalmia Cyclosporine 4.5817120751
Pathway ID Pathway Name
KEGG:04020 Calcium signaling pathway
KEGG:00562 Inositol phosphate metabolism
KEGG:01100 Metabolic pathways
KEGG:04070 Phosphatidylinositol signaling system
Pharmacogenomics Knowledge Base Top
Drug Bank Top
Drugbank ID Action Drug Name Description
DB03265 - Inositol-(1,3,4,5)-Tetrakisphosphate
DB03401 - D-Myo-Inositol-1,4,5-Triphosphate
DB03431 - Adenosine-5'-Diphosphate
DB04395 - Phosphoaminophosphonic Acid-Adenylate Ester
No data
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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