AutismKB 2.0

Annotation Detail for JUNB


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Basic Information Top
Gene Symbol:JUNB ( AP-1 )
Gene Full Name: jun B proto-oncogene
Band: 19p13.13
Quick LinksEntrez ID:3726; OMIM: 165161; Uniprot ID:JUNB_HUMAN; ENSEMBL ID: ENSG00000171223; HGNC ID: 6205
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
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Pathway IDPathway Name
200039Calcineurin-regulated NFAT-dependent transcription in lymphocytes
200184Downstream signaling in naive CD8+ T cells
200159Calcium signaling in the CD4+ TCR pathway
200124IL6-mediated signaling events
200118AP-1 transcription factor network
200116ATF-2 transcription factor network
200044Validated transcriptional targets of AP1 family members Fra1 and Fra2
Pathway IDPathway Name
P00052TGF-beta signaling pathway
P00031Inflammation mediated by chemokine and cytokine signaling pathway
No data
Related Diseases/Disorders Top
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Desease IDDesease Name
2161Hodgkin's disease
2239Lymphoma
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C031278 2-chloroethyl ethyl sulfide 2-chloroethyl ethyl sulfide results in increased expression of JUNB proteinincreases expression 18675330
C054649 3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] which results in increased expression of JUNB mRNAaffects binding|increases activity|increases expression 10821843
C108123 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased activity of JUNB protein]decreases reaction|increases activity 15772366
C017572 4-nitrotoluene 4-nitrotoluene results in increased expression of JUNB mRNAincreases expression 15618236
D000082 Acetaminophen Acetaminophen affects the expression of JUNB mRNAaffects expression 17562736
15606129
D000082 Acetaminophen Acetaminophen results in increased expression of JUNB mRNAincreases expression 12958197
D000082 Acetaminophen Acetaminophen results in increased expression of JUNB mRNAincreases expression 18346771
D000111 Acetylcysteine Acetylcysteine inhibits the reaction [Asbestos, Crocidolite results in increased expression of JUNB mRNA]decreases reaction|increases expression 15520183
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of JUNB proteinaffects expression 20106945
D000643 Ammonium Chloride Ammonium Chloride affects the expression of JUNB mRNAaffects expression 16483693
D003913 Dextroamphetamine Dextroamphetamine results in increased expression of JUNB mRNAincreases expression 12205029
D003913 Dextroamphetamine SOD1 inhibits the reaction [Dextroamphetamine results in increased expression of JUNB mRNA]decreases reaction|increases expression 12205029
D000661 Amphetamine Amphetamine results in decreased expression of JUNB proteindecreases expression 15814102
D001151 Arsenic Arsenic results in increased expression of JUNB mRNAincreases expression 18039032
C006632 arsenic trioxide arsenic trioxide results in decreased expression of JUNB mRNAdecreases expression 20458559
C006632 arsenic trioxide arsenic trioxide results in decreased expression of JUNB mRNAdecreases expression 19410645
D017638 Asbestos, Crocidolite Asbestos, Crocidolite results in increased expression of JUNB mRNAincreases expression 18687144
D017638 Asbestos, Crocidolite Acetylcysteine inhibits the reaction [Asbestos, Crocidolite results in increased expression of JUNB mRNA]decreases reaction|increases expression 15520183
D017638 Asbestos, Crocidolite Asbestos, Crocidolite results in increased expression of JUNB mRNAincreases expression 15520183
D017638 Asbestos, Crocidolite Buthionine Sulfoximine promotes the reaction [Asbestos, Crocidolite results in increased expression of JUNB mRNA]increases expression|increases reaction 15520183
D017638 Asbestos, Crocidolite [GCLC protein co-treated with GCLM protein] inhibits the reaction [Asbestos, Crocidolite results in increased expression of JUNB mRNA]affects cotreatment|decreases reaction|increases expression 15520183
D017638 Asbestos, Crocidolite GCLM protein inhibits the reaction [Asbestos, Crocidolite results in increased expression of JUNB mRNA]decreases reaction|increases expression 15520183
D017638 Asbestos, Crocidolite Glutathione inhibits the reaction [Asbestos, Crocidolite results in increased expression of JUNB mRNA]decreases reaction|increases expression 15520183
D001285 Atropine Atropine inhibits the reaction [Pilocarpine results in increased expression of JUNB mRNA]decreases reaction|increases expression 7968354
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of JUNB mRNAincreases expression 20382639
19150397
C072553 benzyloxycarbonylleucyl-leucyl-leucine aldehyde benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUNB protein]]decreases reaction|increases expression 17148446
C020711 beryllium sulfate [beryllium sulfate co-treated with IFNG protein] results in increased expression of JUNB proteinaffects cotreatment|increases expression 10755711
C002791 bismuth tripotassium dicitrate bismuth tripotassium dicitrate results in increased expression of JUNB mRNAincreases expression 15912405
C006780 bisphenol A bisphenol A results in decreased expression of JUNB mRNAdecreases expression 15223131
C005961 bis(tri-n-butyltin)oxide bis(tri-n-butyltin)oxide results in increased expression of JUNB mRNAincreases expression 17553608
D019328 Buthionine Sulfoximine Buthionine Sulfoximine promotes the reaction [Asbestos, Crocidolite results in increased expression of JUNB mRNA]increases expression|increases reaction 15520183
D019256 Cadmium Chloride [sodium arsenite co-treated with Cadmium Chloride co-treated with chromium oxide co-treated with chromous chloride co-treated with lead acetate] results in increased expression of JUNB mRNAaffects cotreatment|increases expression 12634122
C459604 candoxin candoxin results in decreased expression of JUNB mRNAdecreases expression 16309724
C110904 capecitabine JUNB results in decreased susceptibility to [Fluorouracil co-treated with capecitabine]affects cotreatment|decreases response to substance 18678097
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of JUNB mRNAincreases expression 18346771
D002509 Cephaloridine Cephaloridine results in increased expression of JUNB mRNAincreases expression 18172885
C023600 chromium oxide [sodium arsenite co-treated with Cadmium Chloride co-treated with chromium oxide co-treated with chromous chloride co-treated with lead acetate] results in increased expression of JUNB mRNAaffects cotreatment|increases expression 12634122
C017133 chromous chloride [sodium arsenite co-treated with Cadmium Chloride co-treated with chromium oxide co-treated with chromous chloride co-treated with lead acetate] results in increased expression of JUNB mRNAaffects cotreatment|increases expression 12634122
D002994 Clofibrate PPARA protein affects the reaction [Clofibrate results in decreased expression of JUNB mRNA]affects reaction|decreases expression 17585979
D003024 Clozapine Clozapine results in increased expression of JUNB mRNAincreases expression 19695244
12093589
D003042 Cocaine Cocaine affects the expression of JUNB proteinaffects expression 15814102
C402665 CP 31398 CP 31398 results in increased expression of JUNB mRNAincreases expression 15155752
D003474 Curcumin benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUNB protein]]decreases reaction|increases expression 17148446
D003474 Curcumin Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [FOSL1 protein binds to JUNB protein]]affects binding|decreases reaction|increases reaction 17148446
D003474 Curcumin Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUNB protein]decreases reaction|increases expression 17148446
D003474 Curcumin Curcumin results in increased ubiquitination of JUNB proteinincreases ubiquitination 17148446
D016572 Cyclosporine Cyclosporine results in increased expression of JUNB mRNAincreases expression 20106945
C014347 decitabine decitabine affects the expression of JUNB mRNAaffects expression 16505122
C014347 decitabine decitabine affects the methylation of JUNB promoteraffects methylation 17488656
C007262 deoxynivalenol 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased activity of JUNB protein]decreases reaction|increases activity 15772366
C007262 deoxynivalenol deoxynivalenol affects the activity of JUNB proteinaffects activity 10662601
C007262 deoxynivalenol deoxynivalenol results in increased activity of JUNB proteinincreases activity 15772366
C007262 deoxynivalenol deoxynivalenol results in increased expression of JUNB mRNAincreases expression 15681167
15371230
C020735 dibutyldichlorotin dibutyldichlorotin results in increased expression of JUNB mRNAincreases expression 10722888
D002117 Calcitriol Calcitriol results in increased expression of JUNB mRNAincreases expression 14996990
16002434
C062856 dimethylarsine dimethylarsine results in increased phosphorylation of and results in increased activity of JUNB proteinincreases activity|increases phosphorylation 12475910
D004958 Estradiol Estradiol results in increased expression of JUNB mRNAincreases expression 16029874
D004958 Estradiol Estradiol affects the expression of JUNB mRNAaffects expression 15598610
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of JUNB mRNAincreases expression 14976129
17555576
D005472 Fluorouracil Fluorouracil results in increased expression of JUNB mRNAincreases expression 16557594
D005472 Fluorouracil JUNB results in decreased susceptibility to [Fluorouracil co-treated with capecitabine]affects cotreatment|decreases response to substance 18678097
D017965 gamma-Linolenic Acid gamma-Linolenic Acid results in decreased expression of JUNB proteindecreases expression 15318936
D005912 Gliotoxin Gliotoxin results in increased expression of JUNB mRNAincreases expression 18346771
D005978 Glutathione Glutathione inhibits the reaction [Asbestos, Crocidolite results in increased expression of JUNB mRNA]decreases reaction|increases expression 15520183
D006220 Haloperidol 8-Hydroxy-2-(di-n-propylamino)tetralin inhibits the reaction [Haloperidol results in increased expression of JUNB mRNA]decreases reaction|increases expression 19695244
D006220 Haloperidol Haloperidol results in decreased expression of JUNB mRNAdecreases expression 12093589
D006220 Haloperidol Haloperidol results in increased expression of JUNB mRNAincreases expression 12093589
19695244
D016627 Oxidopamine Oxidopamine results in increased localization of and results in increased activity of JUNB proteinincreases activity|increases localization 17368433
D007213 Indomethacin Indomethacin results in increased expression of JUNB mRNAincreases expression 16984733
D007529 Isoflavones Isoflavones affects the expression of JUNB mRNAaffects expression 16365062
C119620 kenpaullone kenpaullone results in increased expression of JUNB proteinincreases expression 17993264
C008261 lead acetate [sodium arsenite co-treated with Cadmium Chloride co-treated with chromium oxide co-treated with chromous chloride co-treated with lead acetate] results in increased expression of JUNB mRNAaffects cotreatment|increases expression 12634122
C482199 lipopolysaccharide, E coli O55-B5 lipopolysaccharide, E coli O55-B5 results in increased expression of JUNB mRNAincreases expression 18346771
D008070 Lipopolysaccharides Lipopolysaccharides results in increased expression of and results in increased activity of JUNB proteinincreases activity|increases expression 10755711
D047311 Luteolin Luteolin results in decreased activity of JUNB proteindecreases activity 16343431
C080197 methylarsine oxide methylarsine oxide results in increased phosphorylation of and results in increased activity of JUNB proteinincreases activity|increases phosphorylation 12475910
C005223 methyleugenol methyleugenol results in increased expression of JUNB mRNAincreases expression 15618236
D008767 Methylmercury Compounds Methylmercury Compounds affects the expression of JUNB mRNAaffects expression 16966085
D008770 Methylnitrosourea Methylnitrosourea results in increased expression of JUNB mRNAincreases expression 17412507
C008493 methylselenic acid methylselenic acid results in decreased expression of JUNB mRNAdecreases expression 12517777
C016599 mono-(2-ethylhexyl)phthalate mono-(2-ethylhexyl)phthalate results in increased expression of JUNB mRNAincreases expression 16809437
C521676 N-((2,2-dimethyl-2,3-dihydro-benzofuran-7-yloxy)ethyl)-3-(cyclopent-1-enyl)-benzylamine N-((2,2-dimethyl-2,3-dihydro-benzofuran-7-yloxy)ethyl)-3-(cyclopent-1-enyl)-benzylamine results in increased expression of JUNB mRNAincreases expression 19695244
D009496 Neurotensin Neurotensin results in increased activity of JUNB proteinincreases activity 17000667
D009496 Neurotensin [Neurotensin results in increased activity of JUNB protein] which results in increased expression of IL8 proteinincreases activity|increases expression 17000667
C022838 nickel chloride nickel chloride results in increased expression of JUNB mRNAincreases expression 12839937
C029938 nickel sulfate nickel sulfate results in increased expression of JUNB mRNAincreases expression 16780908
C029938 nickel sulfate nickel sulfate results in increased expression of JUNB mRNAincreases expression 19131640
D009569 Nitric Oxide Nitric Oxide results in increased activity of JUNB proteinincreases activity 15949472
C014707 nitrosobenzylmethylamine nitrosobenzylmethylamine results in increased expression of JUNB mRNAincreases expression 17616710
D017371 8-Hydroxy-2-(di-n-propylamino)tetralin 8-Hydroxy-2-(di-n-propylamino)tetralin inhibits the reaction [Haloperidol results in increased expression of JUNB mRNA]decreases reaction|increases expression 19695244
D010076 Oxazepam Oxazepam results in decreased expression of JUNB mRNAdecreases expression 15618236
D010126 Ozone Ozone results in increased expression of JUNB mRNAincreases expression 16716893
D010269 Paraquat Paraquat results in increased expression of JUNB mRNAincreases expression 12595580
C093973 PD 98059 PD 98059 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUNB]decreases reaction|increases expression 15666830
D010424 Pentobarbital Pentobarbital results in decreased expression of JUNB proteindecreases expression 8510500
C023036 perfluorooctanoic acid perfluorooctanoic acid results in decreased expression of JUNB mRNAdecreases expression 16221955
D010634 Phenobarbital Phenobarbital results in decreased expression of JUNB mRNAdecreases expression 19270015
D010656 Phenylephrine Phenylephrine results in increased activity of JUNB proteinincreases activity 15949472
D010862 Pilocarpine Atropine inhibits the reaction [Pilocarpine results in increased expression of JUNB mRNA]decreases reaction|increases expression 7968354
D010862 Pilocarpine Pilocarpine results in increased expression of JUNB mRNAincreases expression 7968354
D010862 Pilocarpine Pirenzepine inhibits the reaction [Pilocarpine results in increased expression of JUNB mRNA]decreases reaction|increases expression 7968354
D010890 Pirenzepine Pirenzepine inhibits the reaction [Pilocarpine results in increased expression of JUNB mRNA]decreases reaction|increases expression 7968354
C009131 pyrimidin-2-one beta-ribofuranoside pyrimidin-2-one beta-ribofuranoside affects the expression of JUNB mRNAaffects expression 16505122
C052785 rebamipide rebamipide results in increased expression of JUNB mRNAincreases expression 15104358
D017640 Silicates Silicates results in increased expression of JUNB mRNAincreases expression 11280724
C110881 S-nitro-N-acetylpenicillamine S-nitro-N-acetylpenicillamine results in increased activity of JUNB proteinincreases activity 15949472
C009277 sodium arsenate sodium arsenate results in increased expression of JUNB mRNAincreases expression 11353140
C017947 sodium arsenite sodium arsenite affects the reaction [JUNB protein binds to IVL promoter]affects binding|affects reaction 20006635
C017947 sodium arsenite [sodium arsenite co-treated with Cadmium Chloride co-treated with chromium oxide co-treated with chromous chloride co-treated with lead acetate] results in increased expression of JUNB mRNAaffects cotreatment|increases expression 12634122
C017947 sodium arsenite sodium arsenite results in decreased expression of JUNB mRNAdecreases expression 12016162
C017947 sodium arsenite sodium arsenite results in increased activity of JUNB proteinincreases activity 12220541
C017947 sodium arsenite sodium arsenite results in increased expression of JUNB mRNAincreases expression 12634122
C017947 sodium arsenite sodium arsenite results in increased phosphorylation of and results in increased activity of JUNB proteinincreases activity|increases phosphorylation 12475910
C017947 sodium arsenite sodium arsenite results in increased expression of JUNB mRNAincreases expression 11353140
D013629 Tamoxifen Tamoxifen affects the expression of JUNB mRNAaffects expression 17555576
D013629 Tamoxifen Tamoxifen results in increased expression of JUNB mRNAincreases expression 19031437
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of JUNB mRNAdecreases expression 17884332
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin affects the expression of JUNB proteinaffects expression 16985168
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of JUNB mRNAincreases expression 20106945
D013755 Tetradecanoylphorbol Acetate benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUNB protein]]decreases reaction|increases expression 17148446
D013755 Tetradecanoylphorbol Acetate Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [FOSL1 protein binds to JUNB protein]]affects binding|decreases reaction|increases reaction 17148446
D013755 Tetradecanoylphorbol Acetate Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUNB protein]decreases reaction|increases expression 17148446
D013755 Tetradecanoylphorbol Acetate PD 98059 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUNB]decreases reaction|increases expression 15666830
D013755 Tetradecanoylphorbol Acetate Tetradecanoylphorbol Acetate promotes the reaction [FOSL1 protein binds to JUNB protein]affects binding|increases reaction 17148446
D013755 Tetradecanoylphorbol Acetate Tetradecanoylphorbol Acetate results in increased expression of JUNBincreases expression 15666830
D013755 Tetradecanoylphorbol Acetate Tetradecanoylphorbol Acetate results in increased expression of JUNB proteinincreases expression 17148446
C012589 trichostatin A trichostatin A affects the expression of JUNB mRNAaffects expression 16505122
D014415 Tunicamycin Tunicamycin results in increased expression of JUNB mRNAincreases expression 17127020
D014520 Urethane Urethane results in increased expression of JUNB mRNAincreases expression 16289808
C025643 vinclozolin vinclozolin affects the expression of JUNB mRNAaffects expression 19015723
C090413 WAY 100635 WAY 100635 results in increased expression of JUNB mRNAincreases expression 19695244
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 3.7114745880
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 5.616195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 5.6115322242 14514962 11752688
MESH:D000138 Acidosis Ammonium Chloride 2.7418287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.1117505938
MESH:D055371 Acute Lung Injury Lipopolysaccharides 6.9518653653 11850527
MESH:D055371 Acute Lung Injury nickel sulfate 6.9519131640 12718980 16100012 11954676
MESH:D000230 Adenocarcinoma arsenic trioxide 16.1619825857 11798837
MESH:D000230 Adenocarcinoma Estradiol 16.1611473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 16.1614692618
MESH:D000230 Adenocarcinoma Fluorouracil 16.1617638652
MESH:D000230 Adenocarcinoma Indomethacin 16.1616537180
MESH:D000230 Adenocarcinoma Methylnitrosourea 16.1615688392 15113128
MESH:D000230 Adenocarcinoma Urethane 16.1618316556
MESH:D002282 Adenocarcinoma, Bronchiolo-Alveolar Urethane 4.8715814487
MESH:D000236 Adenoma Indomethacin 5.5411497255
MESH:D000236 Adenoma Urethane 5.5417195641 11497255 10822126 6695378 10530776 16926031 17093202
MESH:D018248 Adenoma, Liver Cell Phenobarbital 7.3717620307
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 7.3716835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 3.8615276417
MESH:D018246 Adrenocortical Adenoma Arsenic 11.0217306315
MESH:D018246 Adrenocortical Adenoma sodium arsenite 11.0216712894 17306315
MESH:D000380 Agranulocytosis Clozapine 4.2514617031 12649775 16160616
MESH:D000382 Agricultural Workers' Diseases Paraquat 2.9711874814
MESH:D019973 Alcohol-Related Disorders Curcumin 4.2417887948
MESH:D000505 Alopecia Isoflavones 4.0417569567
MESH:D016301 Alveolar Bone Loss Indomethacin 4.5317225004
MESH:D000544 Alzheimer Disease Curcumin 7.1715590663
MESH:D000544 Alzheimer Disease Indomethacin 7.1717627676 15579461
MESH:D000544 Alzheimer Disease Nitric Oxide 7.1717556102
MESH:D000544 Alzheimer Disease Ozone 7.1715513908
MESH:D019969 Amphetamine-Related Disorders Amphetamine 5.2316459022 15010207 18475255 16916582
MESH:D000740 Anemia Fluorouracil 6.2717963324 16511603 15504547
MESH:D000740 Anemia Tetrachlorodibenzodioxin 6.2711748828
MESH:D000799 Angioedema Acetaminophen 3.0110982225
MESH:D000855 Anorexia Amphetamine 4.2816101753 16084549 12183048 12005258
MESH:D001008 Anxiety Disorders Pentobarbital 7.0211141031 18313124
MESH:D001008 Anxiety Disorders vinclozolin 7.0219015723
MESH:D001014 Aortic Aneurysm Indomethacin 4.0610231640
MESH:D017544 Aortic Aneurysm, Abdominal Indomethacin 4.0710388637
MESH:D001145 Arrhythmias, Cardiac Phenylephrine 3.3917460149
MESH:D020261 Arsenic Poisoning Arsenic 2.5616251483 12569548 18414634 16835338
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 2.6711256880
MESH:D018771 Arthralgia Indomethacin 4.332160914
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.1015885639
MESH:D001172 Arthritis, Rheumatoid Curcumin 5.8416807698
MESH:D001172 Arthritis, Rheumatoid Indomethacin 5.8411248219
MESH:D001172 Arthritis, Rheumatoid Ozone 5.8415570426
MESH:D001249 Asthma Ozone 2.3317854713 16373670
MESH:D050197 Atherosclerosis Arsenic 5.0819371607 12928151
MESH:D050197 Atherosclerosis Curcumin 5.0818704882
MESH:D001289 Attention Deficit Disorder with Hyperactivity Oxidopamine 4.0514699433
MESH:D001321 Autistic Disorder Acetaminophen 2.1418445737
MESH:D001321 Autistic Disorder Glutathione 2.1418929414 19267885 19056591 16917939
MESH:D001321 Autistic Disorder Haloperidol 2.1418080171 19368416
MESH:D001327 Autoimmune Diseases Curcumin 3.6919761891
MESH:D001477 Bartter Syndrome Indomethacin 4.1810684365
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 11.1316206674
MESH:D001778 Blood Coagulation Disorders Clofibrate 11.1319483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 11.1312125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 2.9615340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.1815746008
MESH:D001862 Bone Resorption bisphenol A 3.1211985600
MESH:D001919 Bradycardia Phenylephrine 3.7315306635
MESH:D001929 Brain Edema Indomethacin 4.1911481608
MESH:D002545 Brain Ischemia Curcumin 7.6616770732
MESH:D002545 Brain Ischemia Indomethacin 7.6612524144
MESH:D001932 Brain Neoplasms Curcumin 3.2217596214
MESH:D001943 Breast Neoplasms Atropine 10.1812762645
MESH:D001943 Breast Neoplasms bisphenol A 10.1817123778
MESH:D001943 Breast Neoplasms Calcitriol 10.1811237771
MESH:D001943 Breast Neoplasms capecitabine 10.1818473752 12972520
MESH:D001943 Breast Neoplasms Curcumin 10.1818462866 18593918 16243823 19250217
MESH:D001943 Breast Neoplasms decitabine 10.1819208741 18320071
MESH:D001943 Breast Neoplasms Estradiol 10.1812948864 17018787 17289903 16675129 17261762 18497071 14630087 19861407
MESH:D001943 Breast Neoplasms Fluorouracil 10.1815136595 18357371 19217205 18608205 16595493 16110121 16557594
MESH:D001943 Breast Neoplasms Indomethacin 10.1817401462
MESH:D001943 Breast Neoplasms methyleugenol 10.1811921183
MESH:D001943 Breast Neoplasms Methylnitrosourea 10.1816253758 14633655 11306469
MESH:D001943 Breast Neoplasms Nitric Oxide 10.1815631943
MESH:D001943 Breast Neoplasms Tamoxifen 10.1820544844 18997820 18629630 20065188 18855134 17440819 18351453 16273361 15565566 16818667 15668708 19103187 19289846 17261762 20135344 19244106 19155303 19410462 19142967 19059307 11161223 21138602 19084267 18821012 16202921 19066611 19011961 19200415 19189212 16873071 19115204 18984771 19221464 17049068 18815881 17242785 17893378 18425577 20390343 20005174 20859285 19288272 21152245 19487384 19189210
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 10.1820435547
MESH:D016535 Bronchial Hyperreactivity Ozone 3.0115516495 19059883 18417511 14754758 18315731 16777450 17626835
MESH:D002051 Burkitt Lymphoma arsenic trioxide 3.5611589617
MESH:D002056 Burns Indomethacin 3.9010459503
MESH:D002100 Cachexia Indomethacin 9.6715141370 16537180 11239499 15625704
MESH:D002100 Cachexia Ozone 9.6716183385
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 3.6416111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 2.9816050911 15721981 18705752 16227642 16097048 15700767 16124888 15673190 16011737 16192424 10355542 3786805
MESH:D002276 Carcinoid Tumor Fluorouracil 3.8316051944
MESH:D002277 Carcinoma Curcumin 10.0618593918
MESH:D002277 Carcinoma Fluorouracil 10.0617121937
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 10.0616835633
MESH:D002280 Carcinoma, Basal Cell Arsenic 3.0615504454 17687452
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 3.7019066611
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 20.813084413
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 20.8121507988 12907637 12619106
MESH:D006528 Carcinoma, Hepatocellular Arsenic 20.8117306315 16507464
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 20.8115553829 14691202 15073043 16217749 11135700
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 20.8118788625
MESH:D006528 Carcinoma, Hepatocellular Estradiol 20.8116924424
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 20.8118930000 17045692 16799960 16332177 17088986 17971768
MESH:D006528 Carcinoma, Hepatocellular Indomethacin 20.8116391822
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 20.8117173139 1701930 20935162 20007298 6705139
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 20.8115276417 17306315 16507464
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 20.8116924424
MESH:D002278 Carcinoma in Situ bisphenol A 4.1617123778
MESH:D018827 Carcinoma, Lewis Lung Indomethacin 3.9111053908
MESH:D018276 Carcinoma, Medullary Indomethacin 4.5318791128 14736730 11352223
MESH:D002289 Carcinoma, Non-Small-Cell Lung Curcumin 2.6218414057
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.0419014326
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 5.1918695887
MESH:D002292 Carcinoma, Renal Cell Indomethacin 5.1917341418
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.3812490120
MESH:D002294 Carcinoma, Squamous Cell Acetylcysteine 27.0517015178
MESH:D002294 Carcinoma, Squamous Cell Arsenic 27.0517687452 18922899 15504454
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 27.0511237771
MESH:D002294 Carcinoma, Squamous Cell Curcumin 27.0518462866
MESH:D002294 Carcinoma, Squamous Cell decitabine 27.0519215824
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 27.0516280240 16757204 18986760 17066447
MESH:D002294 Carcinoma, Squamous Cell Glutathione 27.0517015178
MESH:D002294 Carcinoma, Squamous Cell Indomethacin 27.0512636206 15482327
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 27.0518572023
MESH:D002294 Carcinoma, Squamous Cell Tetradecanoylphorbol Acetate 27.0518922899
MESH:D002295 Carcinoma, Transitional Cell Arsenic 7.0818640142
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 7.0817572228
MESH:D006332 Cardiomegaly Phenylephrine 5.1215728586 16170337 17124262 11754973 11179087 17287366
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 5.1216120746 18670907 18850075
MESH:D002318 Cardiovascular Diseases Arsenic 5.7815738583 17938729 19152805
MESH:D002318 Cardiovascular Diseases Isoflavones 5.7817689850
MESH:D002340 Carotid Artery Diseases Arsenic 3.5918022660 16973168
MESH:D002375 Catalepsy Haloperidol 4.0915215559 1977408
MESH:D002386 Cataract Acetaminophen 5.7210977129
MESH:D002386 Cataract Methylnitrosourea 5.7212484553
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 22.4820889678
MESH:D002471 Cell Transformation, Neoplastic Acetylcysteine 22.4818226522
MESH:D002471 Cell Transformation, Neoplastic Clofibrate 22.481399818
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 22.4812371664
MESH:D002471 Cell Transformation, Neoplastic Estradiol 22.4818566989
MESH:D002471 Cell Transformation, Neoplastic Methylnitrosourea 22.482727394 7505956
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 22.4819524636 20056578
MESH:D002493 Central Nervous System Diseases Phenobarbital 3.454080065
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 2.4516835633
MESH:D002764 Cholecystitis Indomethacin 4.3311181007
MESH:D002779 Cholestasis Cyclosporine 9.8219486331
MESH:D002779 Cholestasis Ethinyl Estradiol 9.8217681005 15861022 16105132 16919318 17333356 17110522 11677210
MESH:D002779 Cholestasis Nitric Oxide 9.8216919318
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 4.7315340226 16354765 8697196 12621046 15668235
MESH:D002972 Cleft Palate Urethane 4.7312810352
MESH:D019970 Cocaine-Related Disorders Cocaine 4.8919606084
MESH:D003072 Cognition Disorders Clozapine 4.1617123785
MESH:D003092 Colitis Curcumin 3.3818200517 16782535 16804969
MESH:D003103 Coloboma Curcumin 3.8018809619
MESH:D003110 Colonic Neoplasms Curcumin 6.3319359593 16340194
MESH:D003110 Colonic Neoplasms decitabine 6.3317616700
MESH:D003110 Colonic Neoplasms Fluorouracil 6.3317016597 16510598 17169374 17725105 17018589 15001691 18772588 17287894 17172411 16340194
MESH:D003110 Colonic Neoplasms Indomethacin 6.3315625704 11260862 15786552 15936596 15963497 15637740
MESH:D015179 Colorectal Neoplasms arsenic trioxide 6.6020501625
MESH:D015179 Colorectal Neoplasms capecitabine 6.6018473752 18448328
MESH:D015179 Colorectal Neoplasms decitabine 6.6018981723
MESH:D015179 Colorectal Neoplasms Fluorouracil 6.6016331619 18288408 20501625 17016601 16303861 15289873 17401013 16391804 17695437 14970324 17454858 17594712 18509181 17255274 18383874 18949393 16524972 17094418 18448328 15148649 16282729 18802399
MESH:D015179 Colorectal Neoplasms Indomethacin 6.6011197048 18059344 17054584 12606626
MESH:D015179 Colorectal Neoplasms Isoflavones 6.6017116718
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.3514669216 17141729
MESH:D016510 Corneal Neovascularization Curcumin 4.0918497527
MESH:D023903 Coronary Restenosis arsenic trioxide 3.4012609071
MESH:D003328 Coronary Thrombosis methyleugenol 8.5916048847
MESH:D003328 Coronary Thrombosis Oxazepam 8.5916048847
MESH:D003329 Coronary Vasospasm capecitabine 5.0217465463
MESH:D018352 Coronavirus Infections Indomethacin 4.8817302372
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 4.2810525206
MESH:D019465 Craniofacial Abnormalities lead acetate 4.2819769572
MESH:D019465 Craniofacial Abnormalities sodium arsenate 4.2810525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 4.2810048152 20055451 15322242
MESH:D003456 Cryptorchidism vinclozolin 3.5614966744
MESH:D003550 Cystic Fibrosis Acetylcysteine 6.8119747007
MESH:D003550 Cystic Fibrosis Glutathione 6.8119747007
MESH:D007644 Darier Disease Fluorouracil 3.9716733453
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 8.3815213294
MESH:D016757 Death, Sudden, Cardiac Haloperidol 8.3820210726
MESH:D003704 Dementia Haloperidol 7.9611575062
MESH:D003704 Dementia Methylmercury Compounds 7.9616140633
MESH:D015140 Dementia, Vascular Nitric Oxide 5.1317556102
MESH:D003711 Demyelinating Diseases Tamoxifen 3.5619031437
MESH:D017449 Dermatitis, Allergic Contact nickel sulfate 2.9416780908 16823706 11298694
MESH:D003924 Diabetes Mellitus, Type 2 Clozapine 5.5016402076
MESH:D003924 Diabetes Mellitus, Type 2 Curcumin 5.5018403477
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 5.5017107852
MESH:D003928 Diabetic Nephropathies Curcumin 10.9318204486
MESH:D003928 Diabetic Nephropathies Estradiol 10.9319279558
MESH:D003928 Diabetic Nephropathies Tamoxifen 10.9319279558
MESH:D003967 Diarrhea 3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol 9.2910611417
MESH:D003967 Diarrhea Atropine 9.2910867622
MESH:D003967 Diarrhea Indomethacin 9.297237001 7907874
MESH:D006970 Disorders of Excessive Somnolence Clozapine 4.7215331141
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 10.8311834606 19420014 19739265 19164858 12958197 12540782 16109766 11743745 14986274 18713872 10774834 14550746 14725611 17562736 16781746 19370779 16227642 11529661 15968718 2444490 18071297 19923254 11461765 12153990 16081117 11739529 17522070 11287661 11421492 12392966 16177239 16393943 19085960 10663392 19416960 10915739 17906064 12594235 12705907 15619225 16485898
MESH:D056486 Drug-Induced Liver Injury Acetylcysteine 10.8311287661
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 10.8319336974 21278145 3732212 2869522 11566570 17522070 7120509 9327722 10092053 10915739 6884620 7440962 6623471 15968718 7179309 4309450 3786805 16177239 15998439 19085960 16227642 15027814
MESH:D056486 Drug-Induced Liver Injury Gliotoxin 10.8319739265
MESH:D056486 Drug-Induced Liver Injury sodium arsenate 10.8318186108
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 10.8320420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.2619426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.1211462148
MESH:D004374 Ductus Arteriosus, Patent Indomethacin 4.3318043480 12774134 18446180 17190690 16133044 16326151
MESH:D004381 Duodenal Ulcer Atropine 15.6011595415
MESH:D004381 Duodenal Ulcer Curcumin 15.6017351913
MESH:D004381 Duodenal Ulcer Indomethacin 15.6016699067 11595415 10671773 17351913 17202747 11535926 11595431 17329845 11991626 17151854 17045617
MESH:D004381 Duodenal Ulcer Pirenzepine 15.6016613094
MESH:D004409 Dyskinesia, Drug-Induced 8-Hydroxy-2-(di-n-propylamino)tetralin 5.6215893579
MESH:D050171 Dyslipidemias Clofibrate 6.9816707586
MESH:D050171 Dyslipidemias Clozapine 6.9816402076
MESH:D004421 Dystonia Phenobarbital 3.241851702
MESH:D004487 Edema Indomethacin 10.5416100529 7990266 19703484 8273558 7907874 8985016 10653021
MESH:D004487 Edema perfluorooctanoic acid 10.5417259670 12083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 10.5411000095 12711302
MESH:D004487 Edema Tetradecanoylphorbol Acetate 10.547812673 11698051 8113982 16716910 8273558 15177302 9599246
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.0715322242 16714409 18230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 10.8415138306
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 10.8412538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 10.8419031437
MESH:D004701 Endocrine Gland Neoplasms decitabine 11.2519294695
MESH:D004701 Endocrine Gland Neoplasms trichostatin A 11.2519294695
MESH:D016889 Endometrial Neoplasms Estradiol 5.4211473722 18566989 19148513
MESH:D016889 Endometrial Neoplasms Tamoxifen 5.4219155303 16202921 20544844 17893378
MESH:D004715 Endometriosis Indomethacin 6.6615652904
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 6.6610568697 9294722
MESH:D019446 Endotoxemia Indomethacin 7.9418509659
MESH:D019446 Endotoxemia Lipopolysaccharides 7.9415821434 15328337 17637181
MESH:D004751 Enteritis Indomethacin 3.9117763956 10567023 16328016
MESH:D020345 Enterocolitis, Necrotizing Indomethacin 4.1817980183
MESH:D004802 Eosinophilia Indomethacin 3.2711298111
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 3.313659116
MESH:D004828 Epilepsies, Partial Phenobarbital 3.043922381 11558140
MESH:D004827 Epilepsy Phenobarbital 5.6320417680
MESH:D004827 Epilepsy Pilocarpine 5.6311162239 19439326 19700373
MESH:D004832 Epilepsy, Absence Phenobarbital 2.846401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 3.457750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 3.203659116
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 10.5320426865
MESH:D004938 Esophageal Neoplasms arsenic trioxide 10.5312903497
MESH:D004938 Esophageal Neoplasms Fluorouracil 10.5316481741 15173087 17638652 16337965 16785472
MESH:D004938 Esophageal Neoplasms Indomethacin 10.5311005569
MESH:D004938 Esophageal Neoplasms nitrosobenzylmethylamine 10.5316704527 15878914 15623463 15547733 16805852 16510608 15150132 15264214 15547721
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.3611564622
MESH:D005221 Fatigue Amphetamine 4.7819890266
MESH:D005234 Fatty Liver arsenic trioxide 25.7115073043
MESH:D005234 Fatty Liver Carbon Tetrachloride 25.7115959796 61145 12631006 19224547 12795759 16239168 16045604 17595544
MESH:D005234 Fatty Liver Clofibrate 25.7119224547
MESH:D005234 Fatty Liver Curcumin 25.7119297423
MESH:D005234 Fatty Liver Cyclosporine 25.7119224547
MESH:D005234 Fatty Liver Ethinyl Estradiol 25.7115345470
MESH:D005234 Fatty Liver Tamoxifen 25.7119224547 14986274
MESH:D052776 Female Urogenital Diseases Tamoxifen 2.6716709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 2.6611858732
MESH:D005317 Fetal Growth Retardation lead acetate 4.6019769572
MESH:D005334 Fever Indomethacin 6.9411852909 10431976 17627676
MESH:D005334 Fever Lipopolysaccharides 6.949205823 11852909
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 3.7114745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 3.3619069698
MESH:D005354 Fibrosarcoma Indomethacin 9.4810962813
MESH:D005354 Fibrosarcoma Methylnitrosourea 9.4811555667
MESH:D005355 Fibrosis Carbon Tetrachloride 19.3618705752
MESH:D005355 Fibrosis Curcumin 19.3618705752
MESH:D005355 Fibrosis Cyclosporine 19.3612168785 12639820
MESH:D005355 Fibrosis Indomethacin 19.3617994277
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 19.3620067830
MESH:D005499 Folliculitis Indomethacin 4.3311298111
MESH:D005534 Foot Diseases Arsenic 4.726392382
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.4816904648
MESH:D005756 Gastritis Acetaminophen 8.3816983495
MESH:D005756 Gastritis Indomethacin 8.3815046732
MESH:D005770 Gastrointestinal Neoplasms Curcumin 3.8918462866
MESH:D030342 Genetic Diseases, Inborn vinclozolin 4.1116973722
MESH:D005832 Genital Diseases, Male vinclozolin 4.4616417039
MESH:D005833 Genital Neoplasms, Female sodium arsenite 3.8616452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.408708960
MESH:D005909 Glioblastoma Curcumin 8.6817596214
MESH:D005909 Glioblastoma Indomethacin 8.6812870263
MESH:D005909 Glioblastoma trichostatin A 8.6818801729
MESH:D005910 Glioma Fluorouracil 7.6316145905
MESH:D005910 Glioma Indomethacin 7.6316487511 18371953
MESH:D005910 Glioma Methylnitrosourea 7.639825942
MESH:D005911 Gliosis Paraquat 4.3311124998
MESH:D005922 Glomerulonephritis, IGA deoxynivalenol 4.3415173396 16524712
MESH:D005923 Glomerulosclerosis, Focal Segmental Indomethacin 3.6011849393
MESH:D018149 Glucose Intolerance sodium arsenate 4.3119446573
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 3.7610696789
MESH:D006073 Gout Indomethacin 4.5311248219
MESH:D006261 Headache Nitric Oxide 4.3511284996 11554966
MESH:D006258 Head and Neck Neoplasms Curcumin 13.5318829502 18462866
MESH:D006258 Head and Neck Neoplasms decitabine 13.5319215824
MESH:D006258 Head and Neck Neoplasms Fluorouracil 13.5315162350 15102660 18337622
MESH:D006258 Head and Neck Neoplasms Indomethacin 13.5315482327
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 1.8311294989 10048152
MESH:D006331 Heart Diseases Urethane 3.6316046796
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 3.6015720958
MESH:D006463 Hemolytic-Uremic Syndrome Lipopolysaccharides 3.6516366002
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.5911000095
MESH:D006501 Hepatic Encephalopathy Indomethacin 3.8215633222
MESH:D006505 Hepatitis Carbon Tetrachloride 2.8219110552 19900420
MESH:D019698 Hepatitis C, Chronic Indomethacin 3.9015135802
MESH:D006529 Hepatomegaly perfluorooctanoic acid 9.943609246
MESH:D006529 Hepatomegaly Phenobarbital 9.9416109766
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 9.9412621046 15340226 16120746
MESH:D015417 Hereditary Sensory and Motor Neuropathy Curcumin 4.2317701891
MESH:D006558 Herpes Genitalis Estradiol 4.1915709030
MESH:D006689 Hodgkin Disease sodium arsenite 2.4812676792
MESH:D019584 Hot Flashes Estradiol 7.6617088409
MESH:D019584 Hot Flashes Isoflavones 7.6614716179 17290160
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.2118606429 16959395 16354765 8697196 15340226
MESH:D006930 Hyperalgesia Acetaminophen 9.2716870215
MESH:D006930 Hyperalgesia Indomethacin 9.2712727271
MESH:D006930 Hyperalgesia perfluorooctanoic acid 9.2712083418
MESH:D034321 Hyperamylasemia Indomethacin 4.8817883296
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 3.7116899240
MESH:D006937 Hypercholesterolemia Curcumin 3.3118704882
MESH:D006940 Hyperemia Indomethacin 9.9912524144
MESH:D006940 Hyperemia Nitric Oxide 9.9911156591
MESH:D017488 Hyperkeratosis, Epidermolytic Arsenic 3.7217050553
MESH:D006948 Hyperkinesis Amphetamine 9.081977408 14960337
MESH:D006948 Hyperkinesis Clozapine 9.0816046005
MESH:D006949 Hyperlipidemias Indomethacin 3.4117546600
MESH:D006973 Hypertension Arsenic 9.0416076760 9931084 11953799
MESH:D006973 Hypertension Cyclosporine 9.0410903974
MESH:D006973 Hypertension Phenylephrine 9.048949925 12717712
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 9.0418670907 18850075
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.2815338365
MESH:D006976 Hypertension, Pulmonary Nitric Oxide 3.7915838368
MESH:D006984 Hypertrophy Phenylephrine 3.8112791704 18502941
MESH:D006987 Hypesthesia Arsenic 4.7216093927
MESH:D007021 Hypospadias Ethinyl Estradiol 3.0116945680 16569931
MESH:D007077 Ileal Diseases Indomethacin 4.1918306037 10574470
MESH:D007079 Ileitis Indomethacin 4.5310651667 10647630 16133968
MESH:D007235 Infant, Premature, Diseases Indomethacin 4.5316133044
MESH:D007247 Infertility, Female Ethinyl Estradiol 2.7012013081
MESH:D007248 Infertility, Male decitabine 18.6417581917
MESH:D007248 Infertility, Male Ethinyl Estradiol 18.6417937319
MESH:D007248 Infertility, Male Methylnitrosourea 18.647193160
MESH:D007248 Infertility, Male Paraquat 18.644850670
MESH:D007248 Infertility, Male sodium arsenite 18.6412646999 15346721
MESH:D007248 Infertility, Male vinclozolin 18.6416467254
MESH:D007249 Inflammation Curcumin 16.5318403477 17151092 16956363
MESH:D007249 Inflammation Indomethacin 16.533291741 12568917 7812673
MESH:D007249 Inflammation Lipopolysaccharides 16.5317237260 17963957 12878042 9205823 17255318
MESH:D007249 Inflammation perfluorooctanoic acid 16.5312083418
MESH:D007249 Inflammation Tamoxifen 16.5319457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 16.5312200463 12878042
MESH:D007249 Inflammation Tetradecanoylphorbol Acetate 16.537562506 7812673 15177302 8273558 11698051
MESH:D015212 Inflammatory Bowel Diseases Curcumin 2.8018200517 18596194
MESH:D007333 Insulin Resistance bisphenol A 5.4716393666
MESH:D007333 Insulin Resistance Estradiol 5.4716393666 16627594
MESH:D007410 Intestinal Diseases Indomethacin 12.1617329856 11686837 15831440 15610444 11713966 18236018 11855677 10210152 17994277
MESH:D007410 Intestinal Diseases Nitric Oxide 12.1611713966 11574821 10210152
MESH:D007410 Intestinal Diseases rebamipide 12.1611686837
MESH:D007414 Intestinal Neoplasms Curcumin 3.4910783313
MESH:D019586 Intracranial Hypertension Indomethacin 4.5315241188
MESH:D019189 Iron Metabolism Disorders Lipopolysaccharides 3.8617255318
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 2.5916580747
MESH:D007579 Jejunal Diseases Indomethacin 4.1910574470 16133968 18306037
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 3.6015604871
MESH:D007642 Keratosis Arsenic 4.1712749816 16930632
MESH:D007674 Kidney Diseases Acetaminophen 16.8712587719 15629191
MESH:D007674 Kidney Diseases Cadmium Chloride 16.8716962696
MESH:D007674 Kidney Diseases Cyclosporine 16.878314463 10903974 18776723
MESH:D007674 Kidney Diseases Estradiol 16.8715618244
MESH:D007674 Kidney Diseases Indomethacin 16.8717190690
MESH:D007674 Kidney Diseases sodium arsenite 16.8720008137
MESH:D007680 Kidney Neoplasms Cyclosporine 12.1412371664
MESH:D007680 Kidney Neoplasms Estradiol 12.1415610895
MESH:D007680 Kidney Neoplasms Fluorouracil 12.1416985049
MESH:D007680 Kidney Neoplasms Tamoxifen 12.1418625569
MESH:D007889 Leiomyoma Curcumin 3.8018555241
MESH:D007896 Leishmaniasis Nitric Oxide 3.9517218153
MESH:D016773 Leishmaniasis, Cutaneous Indomethacin 3.2210320625 12228301 11703811
MESH:D007938 Leukemia arsenic trioxide 7.7115070760
MESH:D007938 Leukemia Curcumin 7.7118462866
MESH:D007938 Leukemia decitabine 7.7119235587 18980019
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 7.2917077332 12560223
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Curcumin 7.2916106398
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 9.0016972261
MESH:D007948 Leukemia, Monocytic, Acute PD 98059 9.0016972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 6.4114633726
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Indomethacin 6.4110785260 16572323 15631656
MESH:D007951 Leukemia, Myeloid arsenic trioxide 7.1119077051
MESH:D007951 Leukemia, Myeloid decitabine 7.1117236224 19117987 18454857
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 6.8319850784 16467208 20471514 17050201 16968895
MESH:D015470 Leukemia, Myeloid, Acute decitabine 6.8317679729 18206229 18704418 19387464 18460780 19010910
MESH:D015470 Leukemia, Myeloid, Acute Indomethacin 6.8318360721
MESH:D015470 Leukemia, Myeloid, Acute trichostatin A 6.8318206229
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 4.6218055864
MESH:D015473 Leukemia, Promyelocytic, Acute Arsenic 5.8117339181
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 5.8115213294 15748426 17712046 17217047 19642359 16330433 9834237 16966277 19075265 15622746 19035177 17869043 16112521 12018890 16891316 19225113 11468182 15336539 12712474 11161223 17107899 16331271 16823087 12679006 17649720
MESH:D015458 Leukemia, T-Cell arsenic trioxide 9.1116882451
MESH:D015458 Leukemia, T-Cell Curcumin 9.1116106398
MESH:D007964 Leukocytosis Indomethacin 4.5316537180
MESH:D007969 Leukomalacia, Periventricular Indomethacin 4.8817980183
MESH:D007970 Leukopenia Lipopolysaccharides 3.8815821434
MESH:D007984 Leydig Cell Tumor perfluorooctanoic acid 10.218812269
MESH:D007984 Leydig Cell Tumor vinclozolin 10.2116417039
MESH:D017880 Limb Deformities, Congenital Methylnitrosourea 3.5815526292
MESH:D008064 Lipidoses Clozapine 5.9817567588
MESH:D008064 Lipidoses Tamoxifen 5.9817567588 15342952
MESH:D008101 Liver Abscess, Amebic Indomethacin 4.8811479899
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 4.8911903743 16943688 17157831 16221502 16239168 17174718 21278145 17334410 11408273
MESH:D008103 Liver Cirrhosis Phenobarbital 4.8921047994
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 8.2812546737 14724832 17869086 12958196 18251166 17944888 16136751 18429990 12649538 20821823 12445418 18187930 15673190 18156304 15925388 15959796 18210741 15057751 15818738 14716833 18472332 18263696 17481882 17565644 16015684 16011737 17761835 18418968 12898905 17976157 18412020 18481824 14748882 13678700 18376398 15893842 15338365 18395095 17922224 12667390 14620537 17525996 18277467 18420326 17698563 16116963 15730626 12445421 18472094 17640975 18395914 15876570 14512876 17900296 12666154 17631135 18006644 16192424 16638106 17766677 17557913 16097048 12632514 12632512 16248980 15650968 15931870 16033810 14716496 18705752 17714472 12609069 17805973 18166357 17708605 15052691 15370692 11481614 17823541 18317297 18054572 15996030 12389079 16027843 18279442 18205269 12741479 12586293 17721639 10355542 15123356 18339082 15362042
MESH:D008106 Liver Cirrhosis, Experimental Curcumin 8.2818006644 18705752 17355460
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 8.2814659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental Indomethacin 8.2818194892
MESH:D008106 Liver Cirrhosis, Experimental Lipopolysaccharides 8.2812878042
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 8.2818564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 8.2812878042
MESH:D008107 Liver Diseases Acetaminophen 9.2112969438 16611625 19014921 11587558 19460945 12587719 19784758 16610002
MESH:D008107 Liver Diseases Arsenic 9.2111134558
MESH:D008107 Liver Diseases Carbon Tetrachloride 9.2115830285 16246199 17285989 16964402 15720792
MESH:D008107 Liver Diseases Curcumin 9.2116956363
MESH:D008107 Liver Diseases Phenobarbital 9.2119363144
MESH:D017093 Liver Failure Carbon Tetrachloride 3.3615123358
MESH:D017114 Liver Failure, Acute Acetaminophen 6.9916871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 6.9914706259 16899240
MESH:D008113 Liver Neoplasms Aflatoxin B1 28.879163691 18177683 2125692 15890375
MESH:D008113 Liver Neoplasms Arsenic 28.8716368122
MESH:D008113 Liver Neoplasms arsenic trioxide 28.8714682389
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 28.8719294768
MESH:D008113 Liver Neoplasms Fluorouracil 28.8715113037 17045692 18383874 16603448
MESH:D008113 Liver Neoplasms perfluorooctanoic acid 28.8714757943 18709148
MESH:D008113 Liver Neoplasms Phenobarbital 28.8719073162 19812893 8742319 15975961 21047994 19482888
MESH:D008113 Liver Neoplasms sodium arsenite 28.8716712894 15276417
MESH:D008113 Liver Neoplasms Tamoxifen 28.8716684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 28.8716984957
MESH:D008113 Liver Neoplasms Urethane 28.8716391232 17559639 17093202
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 12.618603461
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 12.6120377131
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 12.6112014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 12.6117172636 2563599 1399818 6150874 18308698
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 12.6112151625
MESH:D008133 Long QT Syndrome arsenic trioxide 2.7015213294
MESH:D038061 Lower Extremity Deformities, Congenital Methylnitrosourea 4.6616080182
MESH:D008171 Lung Diseases 2-chloroethyl ethyl sulfide 12.7612815614 16252256 18675330
MESH:D008171 Lung Diseases Acetylcysteine 12.7612815614
MESH:D008171 Lung Diseases Ozone 12.768266340 19066396
MESH:D008171 Lung Diseases sodium arsenite 12.7619095001
MESH:D055370 Lung Injury Asbestos, Crocidolite 15.1317365036
MESH:D055370 Lung Injury Lipopolysaccharides 15.1321114838
MESH:D055370 Lung Injury Nitric Oxide 15.1311395602
MESH:D055370 Lung Injury Ozone 15.1320417186
MESH:D008175 Lung Neoplasms marker/mechanism 16289808
MESH:D008175 Lung Neoplasms Aflatoxin B1 20.9814755239
MESH:D008175 Lung Neoplasms Arsenic 20.9817306315 17976673 19168569
MESH:D008175 Lung Neoplasms arsenic trioxide 20.9811798837 19825857
MESH:D008175 Lung Neoplasms Curcumin 20.9816243823 19359593 18462866
MESH:D008175 Lung Neoplasms Fluorouracil 20.9815246190
MESH:D008175 Lung Neoplasms Indomethacin 20.9811053908 11497255 16537180
MESH:D008175 Lung Neoplasms Methylnitrosourea 20.9818062963
MESH:D008175 Lung Neoplasms Ozone 20.988597069 7614698
MESH:D008175 Lung Neoplasms sodium arsenite 20.9816712894 19931552 17306315 15276417 17077188
MESH:D008175 Lung Neoplasms Tamoxifen 20.9818625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 20.9811884234 19555203
MESH:D008175 Lung Neoplasms Tetradecanoylphorbol Acetate 20.9811807781
MESH:D008175 Lung Neoplasms Urethane 20.9810822126 14587096 16204055 17093202 15902970 11062179 11992545 12117781 17255336 16337739 7750092 10530776 11893704 17195641 11544531 12765245 12957351 11497255 15166089 15136453 16289808 16788158 10997738 11074608 16926031 16391232 11807781 11552296 12466968 16007126 11323394 11307925 6695378 10779650 11246140
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 3.9715086387
MESH:D008223 Lymphoma Curcumin 12.8318462866
MESH:D008223 Lymphoma decitabine 12.8319470736
MESH:D008223 Lymphoma Methylnitrosourea 12.8311418001 16257854
MESH:D008223 Lymphoma Nitric Oxide 12.8316166326
MESH:D016393 Lymphoma, B-Cell Methylnitrosourea 4.0114633661
MESH:D016399 Lymphoma, T-Cell Curcumin 3.8916173963
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 2.9519428831
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 12.7311408345 11807958 16891317 17203775
MESH:D008325 Mammary Neoplasms, Experimental methyleugenol 12.7311921183
MESH:D008325 Mammary Neoplasms, Experimental Methylnitrosourea 12.7316827153 11807958 14999141 16619500 12931682 11751437 17020996 15313902 16944150 10767621 15688392 14633655 15113128 16051031 19196723 10838139 17131329
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 12.7319196723 11731420 16827153 14580682 19196722
MESH:D008325 Mammary Neoplasms, Experimental Tetradecanoylphorbol Acetate 12.738985016
MESH:D020149 Manganese Poisoning Estradiol 9.8719453300
MESH:D020149 Manganese Poisoning Tamoxifen 9.8719453300
MESH:D008545 Melanoma Curcumin 9.4817885582 18462866
MESH:D008545 Melanoma decitabine 9.4817785578 16505122
MESH:D008545 Melanoma pyrimidin-2-one beta-ribofuranoside 9.4816505122
MESH:D008545 Melanoma sodium arsenite 9.4816487513 19082730
MESH:D008545 Melanoma Tamoxifen 9.4819393235 12393984
MESH:D008545 Melanoma trichostatin A 9.4816505122
MESH:D018328 Melanoma, Amelanotic Tamoxifen 3.3615990972
MESH:D008546 Melanoma, Experimental Acetaminophen 2.7719513568
MESH:D008569 Memory Disorders Curcumin 7.4317263510
MESH:D008569 Memory Disorders Methylmercury Compounds 7.4318436314
MESH:D001523 Mental Disorders Clozapine 5.7116856516
MESH:D001523 Mental Disorders Haloperidol 5.7116856516
MESH:D008654 Mesothelioma Asbestos, Crocidolite 2.7816966607 16166281 18303189
MESH:D024821 Metabolic Syndrome X Clozapine 3.7219142101
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 3.9516801185
MESH:D008679 Metaplasia Ozone 4.2710496685
MESH:D008881 Migraine Disorders Indomethacin 6.0411903285
MESH:D008881 Migraine Disorders Nitric Oxide 6.0411701602
MESH:D020326 Migraine without Aura Nitric Oxide 4.3311304026 14659530
MESH:D009041 Motion Sickness Dextroamphetamine 4.681613127
MESH:D009062 Mouth Neoplasms Fluorouracil 6.6216757204 18986760
MESH:D009062 Mouth Neoplasms Indomethacin 6.6212636206
MESH:D009069 Movement Disorders Methylmercury Compounds 4.5618436314
MESH:D009101 Multiple Myeloma arsenic trioxide 12.1819417148 11468182 14977855 15949261 19549372
MESH:D009101 Multiple Myeloma Curcumin 12.1819372569
MESH:D009101 Multiple Myeloma decitabine 12.1818172295
MESH:D009101 Multiple Myeloma trichostatin A 12.1818172295
MESH:D009128 Muscle Spasticity 3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol 5.2817220914
MESH:D009134 Muscular Atrophy, Spinal Curcumin 4.1017962980
MESH:D009139 Musculoskeletal Abnormalities sodium arsenate 4.1118186108
MESH:D009182 Mycosis Fungoides arsenic trioxide 3.8318349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 5.7016882451 16105982
MESH:D009190 Myelodysplastic Syndromes decitabine 5.7019010910 16882708 19157545 18608210
MESH:D009203 Myocardial Infarction Cocaine 3.5818072171
MESH:D017202 Myocardial Ischemia Arsenic 6.7415371236
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 6.7412213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 2.6216810080
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 3.6517484760
MESH:D009216 Myopia Atropine 7.6412601066
MESH:D009216 Myopia Pirenzepine 7.6412601066
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 7.7316624393
MESH:D009361 Neoplasm Invasiveness Curcumin 7.7318495463
MESH:D009362 Neoplasm Metastasis Acetylcysteine 10.2514720322
MESH:D009362 Neoplasm Metastasis capecitabine 10.2512972520
MESH:D009362 Neoplasm Metastasis Indomethacin 10.2511239499 11053908 16537180
MESH:D009362 Neoplasm Metastasis Tamoxifen 10.2519393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.1719410462
MESH:D009369 Neoplasms capecitabine 13.5116374040
MESH:D009369 Neoplasms decitabine 13.5119470736 19116145 17925555
MESH:D009369 Neoplasms Fluorouracil 13.5116928823 18600527 18239605
MESH:D009369 Neoplasms Methylnitrosourea 13.5115533788
MESH:D009369 Neoplasms sodium arsenite 13.5111559025
MESH:D009369 Neoplasms Urethane 13.5115625555
MESH:D009374 Neoplasms, Experimental Indomethacin 15.3315625704 10663608
MESH:D009374 Neoplasms, Experimental Methylnitrosourea 15.3312696579
MESH:D009374 Neoplasms, Experimental sodium arsenite 15.3320056578
MESH:D009374 Neoplasms, Experimental Urethane 15.3315582191
MESH:D009376 Neoplasms, Hormone-Dependent Curcumin 8.0812497104
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 8.0819189210 19196722 19200415
MESH:D009389 Neovascularization, Pathologic Estradiol 2.9217289903
MESH:D009402 Nephrosis, Lipoid Cyclosporine 3.6017954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 2.5818481113 19348381
MESH:D009410 Nerve Degeneration Paraquat 3.0616893418
MESH:D009421 Nervous System Malformations bisphenol A 17.1416427766 11399458
MESH:D009421 Nervous System Malformations Estradiol 17.1411399458 16427766
MESH:D009421 Nervous System Malformations Pilocarpine 17.1415987249
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 17.1414600291
MESH:D009423 Nervous System Neoplasms Curcumin 4.7918462866
MESH:D009436 Neural Tube Defects Acetylcysteine 16.5519446573
MESH:D009436 Neural Tube Defects Arsenic 16.5516620997
MESH:D009436 Neural Tube Defects arsenic trioxide 16.5510525206
MESH:D009436 Neural Tube Defects sodium arsenate 16.5519446573 11749123 10525206 18186108
MESH:D009436 Neural Tube Defects sodium arsenite 16.5512854658
MESH:D009442 Neurilemmoma Methylnitrosourea 4.6611555667
MESH:D019636 Neurodegenerative Diseases Acetaminophen 14.5618514411
MESH:D019636 Neurodegenerative Diseases Amphetamine 14.5615183010
MESH:D019636 Neurodegenerative Diseases Indomethacin 14.5612349958
MESH:D019636 Neurodegenerative Diseases Oxidopamine 14.5618514411
MESH:D020078 Neurogenic Inflammation Arsenic 3.6117056641
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 2.8416436463
MESH:D052556 Niemann-Pick Disease, Type C Clofibrate 9.399802331
MESH:D052556 Niemann-Pick Disease, Type C perfluorooctanoic acid 9.399802331
MESH:D009765 Obesity 2-chloroethyl ethyl sulfide 6.0516289378
MESH:D009765 Obesity Clozapine 6.0518515891 19142110
MESH:D009765 Obesity Curcumin 6.0519297423
MESH:D007752 Obstetric Labor, Premature Indomethacin 4.336374098
MESH:D010003 Osteoarthritis Indomethacin 3.117009135
MESH:D010018 Osteomalacia Phenobarbital 3.5417016548
MESH:D010024 Osteoporosis Curcumin 5.7818719352
MESH:D010024 Osteoporosis Isoflavones 5.7816562857
MESH:D010049 Ovarian Diseases bisphenol A 4.1611985600
MESH:D010051 Ovarian Neoplasms Arsenic 24.3717306315
MESH:D010051 Ovarian Neoplasms arsenic trioxide 24.3712452020 19769630 16624393
MESH:D010051 Ovarian Neoplasms Curcumin 24.3718462866 19020741
MESH:D010051 Ovarian Neoplasms decitabine 24.3719331143 19259094
MESH:D010051 Ovarian Neoplasms Estradiol 24.3719401270
MESH:D010051 Ovarian Neoplasms Luteolin 24.3719005980
MESH:D010051 Ovarian Neoplasms sodium arsenite 24.3715276417 17306315
MESH:D010051 Ovarian Neoplasms trichostatin A 24.3719331143
MESH:D010051 Ovarian Neoplasms Urethane 24.3716391232
MESH:D010146 Pain Acetaminophen 4.5616870215
MESH:D010146 Pain Indomethacin 4.5617440234 17627676 13679232 3291741
MESH:D010149 Pain, Postoperative Indomethacin 3.8518702446 12538197
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 22.4815580305
MESH:D010190 Pancreatic Neoplasms Curcumin 22.4819196508 17440100 19401701
MESH:D010190 Pancreatic Neoplasms decitabine 22.4819294695
MESH:D010190 Pancreatic Neoplasms Fluorouracil 22.4815113037 16929163 19003803 16500647
MESH:D010190 Pancreatic Neoplasms Methylnitrosourea 22.4816965848
MESH:D010190 Pancreatic Neoplasms Phenobarbital 22.4816965848
MESH:D010190 Pancreatic Neoplasms Tetradecanoylphorbol Acetate 22.4815976015
MESH:D010190 Pancreatic Neoplasms trichostatin A 22.4819294695
MESH:D010195 Pancreatitis Indomethacin 3.1815028970 17883296
MESH:D016584 Panic Disorder Ethinyl Estradiol 2.9211578682
MESH:D010212 Papilloma Tetradecanoylphorbol Acetate 3.5018922899 12065085 8330346 18404319
MESH:D010235 Paraganglioma arsenic trioxide 3.3919927285
MESH:D010257 Paraneoplastic Syndromes Indomethacin 4.8816537180
MESH:D010300 Parkinson Disease Paraquat 2.4516140633 11445065 11124998 12911755 15824117 15451049 11181820 16510128
MESH:D010302 Parkinson Disease, Secondary Oxidopamine 8.7315893579 11771942
MESH:D010302 Parkinson Disease, Secondary Paraquat 8.7316190885
MESH:D020734 Parkinsonian Disorders Indomethacin 3.4012349958
MESH:D051302 Paroxysmal Hemicrania Indomethacin 4.8811903285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.4112520081
MESH:D010437 Peptic Ulcer Indomethacin 4.3311148446
MESH:D010518 Periodontitis Indomethacin 4.0817225004
MESH:D010523 Peripheral Nervous System Diseases Arsenic 3.4016093927
MESH:D016491 Peripheral Vascular Diseases Arsenic 4.176392382 16905509 15371236
MESH:D010538 Peritonitis Ozone 3.3316369182
MESH:D010911 Pituitary Neoplasms Urethane 4.6116391232
MESH:D010995 Pleural Diseases Asbestos, Crocidolite 4.0910923243
MESH:D011014 Pneumonia Lipopolysaccharides 13.8512224865 11605937
MESH:D011014 Pneumonia Ozone 13.8518381685 18929643 18007984
MESH:D011014 Pneumonia Paraquat 13.8512504350
MESH:D011015 Pneumonia, Aspiration Nitric Oxide 4.5118573544
MESH:D011041 Poisoning Atropine 4.4017849254 18072136
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 2.7718163543
MESH:D011230 Precancerous Conditions Cyclosporine 6.6112371664
MESH:D011230 Precancerous Conditions Phenobarbital 6.612563599
MESH:D047928 Premature Birth Indomethacin 4.3217000239
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 21.8910548101
MESH:D011297 Prenatal Exposure Delayed Effects Methylmercury Compounds 21.8918436314
MESH:D011297 Prenatal Exposure Delayed Effects perfluorooctanoic acid 21.8917132714
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 21.8911222880 11896295 11399792 11118676
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 21.8918220299 19015723 18042343
MESH:D055728 Primary Myelofibrosis decitabine 9.7617616702
MESH:D055728 Primary Myelofibrosis trichostatin A 9.7617616702
MESH:D011469 Prostatic Diseases vinclozolin 4.1118220299
MESH:D011470 Prostatic Hyperplasia Calcitriol 3.9615572423
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 8.0720887781
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 8.0720887781
MESH:D011471 Prostatic Neoplasms Arsenic 4.7816140617
MESH:D011471 Prostatic Neoplasms arsenic trioxide 4.7819131511
MESH:D011471 Prostatic Neoplasms bisphenol A 4.7816740699
MESH:D011471 Prostatic Neoplasms Calcitriol 4.7816289102 12479363 15754350 18247401 16644109
MESH:D011471 Prostatic Neoplasms Curcumin 4.7811398177 15129424 18226269 12497104 18156803 10851300 18769126
MESH:D011471 Prostatic Neoplasms Estradiol 4.7816740699
MESH:D011471 Prostatic Neoplasms Fluorouracil 4.7819082440 18626508
MESH:D011471 Prostatic Neoplasms Isoflavones 4.7816365062 17571952 17219775 17374662
MESH:D011471 Prostatic Neoplasms Methylnitrosourea 4.7815682402 12376480
MESH:D011471 Prostatic Neoplasms methylselenic acid 4.7816205645
MESH:D011471 Prostatic Neoplasms sodium arsenite 4.7816039940
MESH:D011471 Prostatic Neoplasms Tamoxifen 4.7815067354
MESH:D011471 Prostatic Neoplasms trichostatin A 4.7819789329 18798265
MESH:D011472 Prostatitis vinclozolin 4.1118629315
MESH:D011507 Proteinuria Arsenic 6.9621343184
MESH:D011507 Proteinuria Indomethacin 6.9611849393
MESH:D011537 Pruritus Ethinyl Estradiol 2.5015861022 16919318
MESH:D019310 Pseudolymphoma Phenobarbital 3.6612752131
MESH:D011565 Psoriasis Cyclosporine 1.8716882103
MESH:D011595 Psychomotor Agitation Haloperidol 4.1511575062
MESH:D011618 Psychotic Disorders Clozapine 11.1515331141
MESH:D011618 Psychotic Disorders Cocaine 11.1516134406
MESH:D011618 Psychotic Disorders Haloperidol 11.1511575062
MESH:D011629 Puberty, Precocious bisphenol A 3.9610548101
MESH:D011656 Pulmonary Emphysema Curcumin 3.7919168576
MESH:D011658 Pulmonary Fibrosis Asbestos, Crocidolite 4.5617365031 17975199 17322281 15814490
MESH:D011658 Pulmonary Fibrosis Paraquat 4.5617997886 16324872
MESH:D012004 Rectal Neoplasms Fluorouracil 3.3015538739 18286688 18722050 16160472
MESH:D012021 Reflex, Abnormal Pentobarbital 5.2010930210
MESH:D012128 Respiratory Distress Syndrome, Adult 2-chloroethyl ethyl sulfide 15.4716292752 18257742 12210543
MESH:D012128 Respiratory Distress Syndrome, Adult Acetylcysteine 15.4712210543
MESH:D012128 Respiratory Distress Syndrome, Adult Curcumin 15.4718379247 10666014
MESH:D012128 Respiratory Distress Syndrome, Adult Paraquat 15.4711700416
MESH:D012130 Respiratory Hypersensitivity Lipopolysaccharides 3.1410835634
MESH:D012135 Respiratory Sounds Paraquat 3.2611874814
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.0518990726
MESH:D012162 Retinal Degeneration Methylnitrosourea 7.1318172121 18155124
MESH:D012162 Retinal Degeneration Paraquat 7.1316458197
MESH:D012175 Retinoblastoma Methylnitrosourea 4.6611555667
MESH:D012208 Rhabdomyosarcoma decitabine 3.6419155313
MESH:D012509 Sarcoma Curcumin 3.3918462866
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 3.1816646077
MESH:D012555 Schistosomiasis mansoni Nitric Oxide 4.669673227
MESH:D012559 Schizophrenia Clozapine 3.4720521320 17726453 18806925 18855531 16141801 20452607 17123785 20521326 11151749 20580759 19369910 11763009 17667964 20107430 20168265
MESH:D012559 Schizophrenia Haloperidol 3.471830565 19369910 20107430 18513383
MESH:D012640 Seizures Atropine 12.3112660363 17157343 11218047
MESH:D012640 Seizures Cocaine 12.3110454489
MESH:D012640 Seizures Pentobarbital 12.319754883 10087439
MESH:D012640 Seizures Phenobarbital 12.313137016 11442880 16876388 4039156
MESH:D012640 Seizures Pilocarpine 12.3119660546 7750514
MESH:D003294 Seizures, Febrile Phenobarbital 4.006407741
MESH:D018805 Sepsis Curcumin 3.3818389075
MESH:D012852 Sinusitis Phenylephrine 3.887327846
MESH:D012871 Skin Diseases Arsenic 2.4718709164 19834688 17938729 16353154 17453740 16702368 16759981 17548696 6392382 15952646 17050553
MESH:D012878 Skin Neoplasms Arsenic 12.9517976673 17050553 17029826 16251483 19538983 15504454
MESH:D012878 Skin Neoplasms sodium arsenite 12.9518572023 19524636
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 12.9516192470
MESH:D012878 Skin Neoplasms Tetradecanoylphorbol Acetate 12.958330346 11807781 18404319 8985016 12065085
MESH:D012878 Skin Neoplasms Urethane 12.9511807781
MESH:D013088 Spermatocele Ethinyl Estradiol 8.7916709447
MESH:D013088 Spermatocele Tamoxifen 8.7916709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.2219457130
MESH:D016135 Spinal Dysraphism sodium arsenite 3.1312854658
MESH:D013226 Status Epilepticus Pilocarpine 5.4215987249 19055492 11259499 19430551 19951488 19570321 15857427
MESH:D019956 Stereotypic Movement Disorder Amphetamine 5.581977408
MESH:D013272 Stomach Diseases Indomethacin 8.0117160473 18209964 17207306 17638125 15038085 18545984 15472012 16184426 10215738 16113693 10486359 16280098 10192188
MESH:D013272 Stomach Diseases rebamipide 8.0116184426
MESH:D013274 Stomach Neoplasms arsenic trioxide 8.1517007042
MESH:D013274 Stomach Neoplasms decitabine 8.1519037991
MESH:D013274 Stomach Neoplasms Fluorouracil 8.1516424979 19084572 17522103 15786421 19015929 18567086 18396642 17498489 16951190 17172411
MESH:D013274 Stomach Neoplasms Indomethacin 8.1515609394
MESH:D013274 Stomach Neoplasms Methylnitrosourea 8.1518593901 15930296 16257854
MESH:D013274 Stomach Neoplasms nitrosobenzylmethylamine 8.1512958204 17575124
MESH:D013274 Stomach Neoplasms rebamipide 8.1515993841
MESH:D013276 Stomach Ulcer Acetylcysteine 14.8617918041
MESH:D013276 Stomach Ulcer Atropine 14.8611595415
MESH:D013276 Stomach Ulcer Curcumin 14.8616631530 19188055
MESH:D013276 Stomach Ulcer Indomethacin 14.8616252198 16150113 16934674 16631530 14567935 18431645 11523592 17918041 12467913 16397915 12787963 15138204 12498302 18193104 18209962 12077510 12500499 17135157 18237397 17895592 15255614 1323529 17654042 16755016 18726076 10878458 11595415 15104355 18087811 18543354 11145282 10750652 11729361 17977527 18299717 17627676 18181030 10423059 16169175 11906479 11595431 17657623
MESH:D013276 Stomach Ulcer Nitric Oxide 14.8615138204
MESH:D019966 Substance-Related Disorders bisphenol A 3.1716045194 16684133
MESH:D013375 Substance Withdrawal Syndrome Pentobarbital 4.259754883 11529278
MESH:D017180 Tachycardia, Ventricular Haloperidol 3.9320210726
MESH:D013921 Thrombocytopenia Lipopolysaccharides 3.4415821434
MESH:D019851 Thrombophilia Ethinyl Estradiol 2.8511994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.4515669648
MESH:D013953 Thymus Neoplasms Methylnitrosourea 4.4111418001
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.0712697716
MESH:D013964 Thyroid Neoplasms 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine 19.6216940797
MESH:D013964 Thyroid Neoplasms arsenic trioxide 19.6219014326
MESH:D013964 Thyroid Neoplasms decitabine 19.6217967635
MESH:D013964 Thyroid Neoplasms Indomethacin 19.6218791128 14736730 11352223
MESH:D013964 Thyroid Neoplasms Methylnitrosourea 19.627505956 3078959
MESH:D013964 Thyroid Neoplasms Phenobarbital 19.621399818
MESH:D013978 Tibial Fractures Estradiol 3.8519048282
MESH:D014062 Tongue Neoplasms Fluorouracil 3.2616280240
MESH:D016171 Torsades de Pointes arsenic trioxide 3.1515213294
MESH:D014202 Tremor Atropine 9.0417594079
MESH:D014202 Tremor Pilocarpine 9.0417594079
MESH:D014456 Ulcer Indomethacin 4.0717380554 10574470
MESH:D001749 Urinary Bladder Neoplasms Arsenic 14.4918640142 11144890 17306315 19322015 19429237 17976673 15987713
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 14.4911780464 20435036 12973940 12845720
MESH:D001749 Urinary Bladder Neoplasms Curcumin 14.4918593936
MESH:D001749 Urinary Bladder Neoplasms decitabine 14.4919087683 17616700
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 14.4916452187 17306315 11723127 16712894
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 14.4917572228 16712894 8653321
MESH:D014565 Urogenital Neoplasms Curcumin 4.4418462866
MESH:D014581 Urticaria Acetaminophen 2.2310982225
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 7.0716803524
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 7.0711813266
MESH:D014591 Uterine Diseases bisphenol A 4.1714652134
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 2.5214692618
MESH:D014604 Uveal Neoplasms decitabine 4.0817785578
MESH:D014605 Uveitis Cyclosporine 3.151336536
MESH:D014652 Vascular Diseases Arsenic 9.1217056641
MESH:D014652 Vascular Diseases sodium arsenite 9.1217056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 3.7612125929
MESH:D019043 Vascular Neoplasms Urethane 5.0710620525
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 2.7914671159 15869587
MESH:D014839 Vomiting Indomethacin 3.9111897121
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.4115886252
MESH:D015430 Weight Gain Clozapine 3.7616402076 17502770 20564506 20107430 16141801 20521320
MESH:D015431 Weight Loss Clozapine 4.2617933447
MESH:D014985 Xerophthalmia Cyclosporine 3.6017120751
Pathway ID Pathway Name
KEGG:04380 Osteoclast differentiation
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA30007
    • No data
    No data
    Releated drug ID Related drug Name
    PA164743471adenosine triphosphate
    PA451578tacrolimus
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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