Annotation Detail for KAL1
Basic Information
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| Desease ID | Desease Name |
|---|
| 1832 | Congenital abnormality |
| 1955 | Urogenital abnormalities |
| Desease Name |
|---|
| Kallmann syndrome |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| C014347 |
decitabine |
decitabine results in increased expression of KAL1 mRNA | increases expression | 19151715
|
| D002117 |
Calcitriol |
Calcitriol results in increased expression of KAL1 mRNA | increases expression | 16002434
|
| D019812 |
Heparan Sulfate Proteoglycans |
[Heparan Sulfate Proteoglycans binds to FGF2 protein binds to FGFR1 protein] which binds to KAL1 protein | affects binding | 15548653
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D001943 |
Breast Neoplasms |
|
Calcitriol |
2.39 | 11237771 |
| MESH:D001943 |
Breast Neoplasms |
|
decitabine |
2.39 | 19208741 18320071 |
| MESH:D002294 |
Carcinoma, Squamous Cell |
|
Calcitriol |
5.22 | 11237771 |
| MESH:D002294 |
Carcinoma, Squamous Cell |
|
decitabine |
5.22 | 19215824 |
| MESH:D003110 |
Colonic Neoplasms |
|
decitabine |
2.39 | 17616700 |
| MESH:D015179 |
Colorectal Neoplasms |
|
decitabine |
2.11 | 18981723 |
| MESH:D004681 |
Encephalomyelitis, Autoimmune, Experimental |
|
Calcitriol |
4.52 | 15138306 |
| MESH:D004701 |
Endocrine Gland Neoplasms |
|
decitabine |
5.98 | 19294695 |
| MESH:D006258 |
Head and Neck Neoplasms |
|
decitabine |
3.77 | 19215824 |
| MESH:D007248 |
Infertility, Male |
|
decitabine |
3.48 | 17581917 |
| MESH:D017436 |
Kallmann Syndrome |
marker/mechanism |
|
| |
| MESH:D007938 |
Leukemia |
|
decitabine |
3.25 | 18980019 19235587 |
| MESH:D007951 |
Leukemia, Myeloid |
|
decitabine |
4.49 | 18454857 17236224 19117987 |
| MESH:D015470 |
Leukemia, Myeloid, Acute |
|
decitabine |
2.43 | 18460780 18206229 17679729 19387464 19010910 18704418 |
| MESH:D015477 |
Leukemia, Myelomonocytic, Chronic |
|
decitabine |
6.33 | 18055864 |
| MESH:D008223 |
Lymphoma |
|
decitabine |
3.73 | 19470736 |
| MESH:D008545 |
Melanoma |
|
decitabine |
2.29 | 16505122 17785578 |
| MESH:D009101 |
Multiple Myeloma |
|
decitabine |
3.65 | 18172295 |
| MESH:D009190 |
Myelodysplastic Syndromes |
|
decitabine |
3.60 | 16882708 18608210 19157545 19010910 |
| MESH:D009369 |
Neoplasms |
|
decitabine |
2.89 | 19470736 19116145 17925555 |
| MESH:D010051 |
Ovarian Neoplasms |
|
decitabine |
2.75 | 19259094 19331143 |
| MESH:D010190 |
Pancreatic Neoplasms |
|
decitabine |
2.89 | 19294695 |
| MESH:D055728 |
Primary Myelofibrosis |
|
decitabine |
5.38 | 17616702 |
| MESH:D011470 |
Prostatic Hyperplasia |
|
Calcitriol |
5.52 | 15572423 |
| MESH:D011471 |
Prostatic Neoplasms |
|
Calcitriol |
3.48 | 15754350 16289102 18247401 12479363 16644109 |
| MESH:D012208 |
Rhabdomyosarcoma |
|
decitabine |
4.93 | 19155313 |
| MESH:D013274 |
Stomach Neoplasms |
|
decitabine |
2.10 | 19037991 |
| MESH:D013964 |
Thyroid Neoplasms |
|
decitabine |
3.67 | 17967635 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
decitabine |
2.85 | 19087683 17616700 |
| MESH:D014604 |
Uveal Neoplasms |
|
decitabine |
5.78 | 17785578 |
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