AutismKB 2.0

Annotation Detail for CD82


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Basic Information Top
Gene Symbol:CD82 ( 4F9,C33,GR15,IA4,KAI1,R2,SAR2,ST6,TSPAN27 )
Gene Full Name: CD82 molecule
Band: 11p11.2
Quick LinksEntrez ID:3732; OMIM: 600623; Uniprot ID:CD82_HUMAN; ENSEMBL ID: ENSG00000085117; HGNC ID: 6210
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04115p53 signaling pathway
No data
Pathway IDPathway Name
200101Direct p53 effectors
Pathway IDPathway Name
P00059p53 pathway
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1934Cancer
1912Penile disease
No data
No data
Desease Name
Prostate cancer, susceptibility to
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C046783 11,12-epoxy-5,8,14-eicosatrienoic acid 11,12-epoxy-5,8,14-eicosatrienoic acid inhibits the reaction [Terfenadine analog results in increased expression of CD82 protein]decreases reaction|increases expression 19289568
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of CD82 mRNAaffects expression 21346803
D000643 Ammonium Chloride Ammonium Chloride affects the expression of CD82 mRNAaffects expression 16483693
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in increased expression of CD82 mRNAincreases expression 15336504
D002251 Carbon Tetrachloride Carbon Tetrachloride results in decreased expression of CD82 mRNAdecreases expression 17484886
D003687 Dehydroepiandrosterone Dehydroepiandrosterone results in increased expression of CD82 mRNAincreases expression 17823450
D004041 Dietary Fats Dietary Fats results in decreased expression of CD82 mRNAdecreases expression 18042831
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of CD82 mRNAincreases expression 17823450
D004281 Docosahexaenoic Acids Docosahexaenoic Acids results in decreased expression of CD82 mRNAdecreases expression 16623957
D004958 Estradiol [Estradiol co-treated with Tamoxifen] results in increased expression of CD82 mRNAaffects cotreatment|increases expression 17823450
D004958 Estradiol Estradiol results in increased expression of CD82 mRNAincreases expression 17823450
D019833 Genistein Genistein results in increased expression of CD82 mRNAincreases expression 18847459
C041786 palm oil palm oil results in decreased expression of CD82 mRNAdecreases expression 18042831
C006253 pirinixic acid pirinixic acid results in decreased expression of CD82 mRNAdecreases expression 17426115
C410733 scriptaid scriptaid affects the expression of CD82 mRNAaffects expression 18813790
D013629 Tamoxifen [Estradiol co-treated with Tamoxifen] results in increased expression of CD82 mRNAaffects cotreatment|increases expression 17823450
D016593 Terfenadine 11,12-epoxy-5,8,14-eicosatrienoic acid inhibits the reaction [Terfenadine analog results in increased expression of CD82 protein]decreases reaction|increases expression 19289568
D016593 Terfenadine Terfenadine analog results in increased expression of CD82 proteinincreases expression 19289568
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.5814745880
MESH:D000138 Acidosis Ammonium Chloride 3.5818287403
MESH:D055371 Acute Lung Injury pirinixic acid 3.1218653653
MESH:D000230 Adenocarcinoma Estradiol 4.4711473722
MESH:D000230 Adenocarcinoma Genistein 4.4711473722
MESH:D018248 Adenoma, Liver Cell pirinixic acid 3.5016434500
MESH:D000309 Adrenal Insufficiency Dehydroepiandrosterone 5.7817302879
OMIM:607154 ALLERGIC RHINITIS Terfenadine 5.6716037679
MESH:D000686 Amyloidosis Diethylstilbestrol 4.4915469931
MESH:D001161 Arteriosclerosis Dietary Fats 3.9015238619
MESH:D001321 Autistic Disorder Docosahexaenoic Acids 3.2018582451
MESH:D001778 Blood Coagulation Disorders pirinixic acid 3.1519483382
MESH:D001943 Breast Neoplasms Dietary Fats 2.3520435547
MESH:D001943 Breast Neoplasms Diethylstilbestrol 2.3517129689 15324884
MESH:D001943 Breast Neoplasms Estradiol 2.3512948864 16675129 17289903 19861407 17018787 18497071 14630087 17261762
MESH:D001943 Breast Neoplasms Genistein 2.3517200150 16541309 16873071
MESH:D001943 Breast Neoplasms Tamoxifen 2.3519221464 17049068 19200415 18984771 19084267 19066611 19011961 17440819 20859285 19244106 19189212 16818667 17893378 18821012 16873071 18997820 21152245 19410462 18815881 17261762 19189210 20065188 11161223 19288272 18351453 21138602 20544844 16273361 20135344 17242785 19142967 19059307 18425577 20390343 15668708 19487384 20005174 19155303 18629630 19103187 15565566 19289846 16202921 19115204 18855134
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.4816111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.7910355542 16124888 16097048 16011737 18705752 16050911 15700767 16227642 15673190 16192424 15721981 3786805
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.5219066611
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 11.4116705839
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 11.4118788625
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 11.4115948411 16924424
MESH:D006528 Carcinoma, Hepatocellular Estradiol 11.4116924424
MESH:D006528 Carcinoma, Hepatocellular Genistein 11.4116924424
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 11.4116924424
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.6217572228
MESH:D002318 Cardiovascular Diseases Genistein 3.3016332659
MESH:D002471 Cell Transformation, Neoplastic Estradiol 2.7718566989
MESH:D002779 Cholestasis pirinixic acid 2.8319176532
MESH:D003110 Colonic Neoplasms Genistein 2.2917182828
MESH:D003456 Cryptorchidism Diethylstilbestrol 4.5716002989 12952375
MESH:D003490 Cyanosis 2,4-dinitrotoluene 4.0318551238
MESH:D003550 Cystic Fibrosis Docosahexaenoic Acids 4.6819747007
MESH:D003711 Demyelinating Diseases Tamoxifen 4.3819031437
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.4318249437
MESH:D003922 Diabetes Mellitus, Type 1 Dehydroepiandrosterone 3.6916616286
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 2.4916647724
MESH:D003928 Diabetic Nephropathies Estradiol 8.8519279558
MESH:D003928 Diabetic Nephropathies Tamoxifen 8.8519279558
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 3.8818551238 21346803
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 3.8821278145 6623471 19085960 4309450 7440962 16227642 2869522 17522070 16177239 9327722 10915739 15998439 15968718 10092053 7179309 15027814 3786805 11566570 3732212 19336974 7120509 6884620
MESH:D050171 Dyslipidemias Dietary Fats 3.4518367378
MESH:D004487 Edema pirinixic acid 2.4912083418
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 3.5519031437
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 11.9616402032
MESH:D004714 Endometrial Hyperplasia Genistein 11.9616402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 17.8215700306 16804899
MESH:D016889 Endometrial Neoplasms Estradiol 17.8218566989 11473722 19148513
MESH:D016889 Endometrial Neoplasms Genistein 17.8211473722
MESH:D016889 Endometrial Neoplasms Tamoxifen 17.8217893378 16202921 20544844 19155303
MESH:D005234 Fatty Liver Carbon Tetrachloride 18.8212795759 17595544 12631006 16045604 15959796 19224547 16239168 61145
MESH:D005234 Fatty Liver Dietary Fats 18.8217967931 18296743 19551842 19004024
MESH:D005234 Fatty Liver pirinixic acid 18.8220131406 19236843
MESH:D005234 Fatty Liver Tamoxifen 18.8219224547 14986274
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 8.2216611131 16002989 16513791 16534752 15751030
MESH:D052776 Female Urogenital Diseases Tamoxifen 8.2216709447
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.5514745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.2019069698
MESH:D005355 Fibrosis Carbon Tetrachloride 8.8518705752
MESH:D005355 Fibrosis Dietary Fats 8.8518296743
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 4.9716452187
MESH:D005909 Glioblastoma Genistein 3.2616598420
MESH:D006333 Heart Failure pirinixic acid 2.5420558911
MESH:D006505 Hepatitis Carbon Tetrachloride 3.6019900420 19110552
MESH:D006529 Hepatomegaly pirinixic acid 3.0119176532 18467677 16221962 19772884
MESH:D006558 Herpes Genitalis Estradiol 5.0615709030
MESH:D019584 Hot Flashes Estradiol 3.7817088409
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.5516899240
MESH:D006937 Hypercholesterolemia Dietary Fats 3.6021332399
MESH:D006943 Hyperglycemia pirinixic acid 3.1920558911
MESH:D006949 Hyperlipidemias Dietary Fats 3.6221332399
MESH:D006965 Hyperplasia Diethylstilbestrol 4.4512960047 14722030
MESH:D006967 Hypersensitivity Terfenadine 5.242570798
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.1015338365
MESH:D007021 Hypospadias Diethylstilbestrol 4.5916002989
MESH:D007246 Infertility Diethylstilbestrol 4.3615036965
MESH:D007249 Inflammation Dietary Fats 5.1020412841
MESH:D007249 Inflammation Tamoxifen 5.1019457130
MESH:D007333 Insulin Resistance Dietary Fats 12.3018457598 11836018
MESH:D007333 Insulin Resistance Estradiol 12.3016393666 16627594
MESH:D007333 Insulin Resistance pirinixic acid 12.3016306350
MESH:D007674 Kidney Diseases Estradiol 2.5815618244
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 17.8116705839
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 17.8115003126 14681315 16762066
MESH:D007680 Kidney Neoplasms Estradiol 17.8115610895
MESH:D007680 Kidney Neoplasms Tamoxifen 17.8118625569
MESH:D007859 Learning Disorders Diethylstilbestrol 4.0717184923
MESH:D007938 Leukemia Genistein 3.0217468513 18980019
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Docosahexaenoic Acids 5.0117077332
MESH:D008064 Lipidoses Tamoxifen 3.1617567588 15342952
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 6.6311903743 16943688 21278145 17157831 17174718 16239168 16221502 11408273 17334410
MESH:D008103 Liver Cirrhosis Dietary Fats 6.6318296743
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 6.7417761835 18251166 17721639 15931870 18187930 18277467 12632512 15673190 12958196 18472094 18339082 12649538 18210741 17714472 12586293 17557913 10355542 14716496 17708605 18472332 15123356 17869086 16192424 17481882 15362042 14748882 15996030 16136751 17766677 18412020 17631135 12898905 15338365 12632514 18279442 15818738 12741479 17922224 17805973 16638106 16248980 18395914 18156304 18376398 14512876 15730626 18006644 12546737 15057751 18429990 16116963 18395095 17944888 12667390 15370692 15893842 17525996 17565644 17640975 16097048 15650968 16027843 14620537 18054572 13678700 15959796 15052691 18205269 11481614 17823541 12609069 12445418 15876570 15925388 16015684 18481824 18263696 17976157 12666154 17698563 14724832 16033810 18420326 12445421 17900296 18317297 16011737 18705752 20821823 12389079 14716833 18418968 18166357
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 6.7414716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Genistein 6.7417823541
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 6.7415474484
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 6.7418564211
MESH:D008107 Liver Diseases Carbon Tetrachloride 4.5517285989 15830285 16246199 15720792 16964402
MESH:D008107 Liver Diseases Docosahexaenoic Acids 4.5517056761
MESH:D017093 Liver Failure Carbon Tetrachloride 4.1815123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 3.6914706259 16899240
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 14.2819294768
MESH:D008113 Liver Neoplasms Dehydroepiandrosterone 14.2818709148
MESH:D008113 Liver Neoplasms Diethylstilbestrol 14.2815890375 16712894
MESH:D008113 Liver Neoplasms pirinixic acid 14.2816377806 20007298 15890375
MESH:D008113 Liver Neoplasms Tamoxifen 14.2816684651
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 6.4112014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Dehydroepiandrosterone 6.418603461
MESH:D008133 Long QT Syndrome Terfenadine 5.088772706
MESH:D008175 Lung Neoplasms Tamoxifen 1.7418625569
MESH:D008181 Lupus Nephritis Diethylstilbestrol 5.1715166399
MESH:D008223 Lymphoma Diethylstilbestrol 3.4715700306
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 5.5516002989
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.7819428831
MESH:D008325 Mammary Neoplasms, Experimental Dehydroepiandrosterone 14.3516457693
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 14.3517203775 11807958 16891317 11408345
MESH:D008325 Mammary Neoplasms, Experimental Genistein 14.3512929590 14578162
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 14.3519196723 11731420 16827153 14580682 19196722
MESH:D020149 Manganese Poisoning Estradiol 12.7519453300
MESH:D020149 Manganese Poisoning Tamoxifen 12.7519453300
MESH:D008545 Melanoma Tamoxifen 1.8819393235 12393984
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.2015990972
MESH:D009135 Muscular Diseases pirinixic acid 3.5216239165
MESH:D009203 Myocardial Infarction Genistein 5.6817141266
MESH:D009203 Myocardial Infarction pirinixic acid 5.6819151258
MESH:D015428 Myocardial Reperfusion Injury Estradiol 14.1816810080
MESH:D015428 Myocardial Reperfusion Injury Genistein 14.1817141266
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 14.1816411023
MESH:D009336 Necrosis 2,4-dinitrotoluene 3.8818551238
MESH:D009362 Neoplasm Metastasis Tamoxifen 2.5519393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.5219410462
MESH:D009369 Neoplasms Diethylstilbestrol 5.0415313581
MESH:D009369 Neoplasms pirinixic acid 5.0417405874
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 4.0319189210 19200415 19196722
MESH:D009389 Neovascularization, Pathologic Estradiol 3.7517289903
MESH:D009421 Nervous System Malformations Diethylstilbestrol 16.5511399458
MESH:D009421 Nervous System Malformations Estradiol 16.5516427766 11399458
MESH:D009421 Nervous System Malformations Genistein 16.5516427766
MESH:D009765 Obesity Dietary Fats 4.4417217161 19632207 20518802 20132043 21332399 18674790 16723640 11836018 18457598
MESH:D009765 Obesity pirinixic acid 4.4420558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 3.4312819281 16049721
MESH:D010024 Osteoporosis Genistein 3.2519401787
MESH:D015663 Osteoporosis, Postmenopausal Dehydroepiandrosterone 10.4616397352
MESH:D015663 Osteoporosis, Postmenopausal Genistein 10.4616169203
MESH:D010051 Ovarian Neoplasms Estradiol 4.9019401270
MESH:D010051 Ovarian Neoplasms Genistein 4.9019005980
MESH:D010900 Pituitary Diseases Diethylstilbestrol 5.2014722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 4.6816977796 15687265
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 4.1317184923
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.8920887781
MESH:D011471 Prostatic Neoplasms marker/mechanism
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 2.0915846301 17136230 15046698
MESH:D011471 Prostatic Neoplasms Estradiol 2.0916740699
MESH:D011471 Prostatic Neoplasms Genistein 2.0915256057 15378649 16925846
MESH:D011471 Prostatic Neoplasms Tamoxifen 2.0915067354
MESH:D015427 Reperfusion Injury pirinixic acid 2.3919058328
MESH:D012221 Rhinitis, Allergic, Perennial Terfenadine 5.948201490
MESH:D012640 Seizures 2,4-dinitrotoluene 2.5318551238
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 2.698532709
MESH:D013088 Spermatocele Diethylstilbestrol 11.9516002989 16709447
MESH:D013088 Spermatocele Tamoxifen 11.9516709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 4.0619457130
MESH:D013274 Stomach Neoplasms Docosahexaenoic Acids 3.0619015929
MESH:D013978 Tibial Fractures Estradiol 4.7219048282
MESH:D016171 Torsades de Pointes Terfenadine 5.718256756
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 8.3616049721
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 8.3616712894 16452187 17306315
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 8.3617572228 8653321 16712894
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 4.3310091137
MESH:D014581 Urticaria Terfenadine 5.292569995 2565098 2568013 2859714 2885854
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 4.0416175088
MESH:D014591 Uterine Diseases Diethylstilbestrol 5.2014652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 4.0816690809 15809267
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 4.4516513791 16002989
MESH:D015430 Weight Gain Dietary Fats 3.7416723640
Pathway ID Pathway Name
KEGG:04115 p53 signaling pathway
Pharmacogenomics Knowledge Base Top
Drug Bank Top

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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