Annotation Detail for AREG
Basic Information Top
| Gene Symbol: | AREG ( AR,AREGB,CRDGF,MGC13647,SDGF ) |
|---|---|
| Gene Full Name: | amphiregulin |
| Band: | 4q13.3 |
| Quick Links | Entrez ID:374; OMIM: 104640; Uniprot ID:AREG_HUMAN; ENSEMBL ID: ENSG00000109321; HGNC ID: 651 |
| Relate to Another Database: | SFARIGene; denovo-db |
| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| C051452 | 1,2,3,7,8-pentachlorodibenzo-p-dioxin | 1,2,3,7,8-pentachlorodibenzo-p-dioxin results in increased expression of AREG mRNA | increases expression | 16929009 |
| C023514 | 2,6-dinitrotoluene | 2,6-dinitrotoluene results in increased expression of AREG mRNA | increases expression | 20406850 |
| C108123 | 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine | 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine results in decreased secretion of AREG protein | decreases secretion | 15615697 |
| C055492 | 4-hydroxy-N-desmethyltamoxifen | 4-hydroxy-N-desmethyltamoxifen inhibits the reaction [Estradiol results in increased expression of AREG mRNA] | decreases reaction|increases expression | 19244106 |
| C016601 | 4-hydroxytamoxifen | 4-hydroxytamoxifen results in decreased expression of AREG mRNA | decreases expression | 16514628 |
| C107875 | 6-(methylamino)pyrido(3,4-d)pyrimidine | 6-(methylamino)pyrido(3,4-d)pyrimidine results in decreased secretion of AREG protein | decreases secretion | 15615697 |
| C469552 | A 419259 | A 419259 inhibits the reaction [GRP protein results in increased cleavage of and results in increased secretion of AREG protein] | decreases reaction|increases cleavage|increases secretion | 15342401 |
| D000082 | Acetaminophen | Acetaminophen affects the expression of AREG mRNA | affects expression | 17562736 |
| D000643 | Ammonium Chloride | Ammonium Chloride affects the expression of AREG mRNA | affects expression | 16483693 |
| D001151 | Arsenic | Arsenic results in decreased expression of AREG mRNA | decreases expression | 19654921 |
| D017638 | Asbestos, Crocidolite | Asbestos, Crocidolite results in increased expression of AREG mRNA | increases expression | 18687144 |
| C447119 | bazedoxifene acetate | bazedoxifene acetate inhibits the reaction [Estrogens, Conjugated (USP) results in increased expression of AREG mRNA] | decreases reaction|increases expression | 19022889 |
| C447119 | bazedoxifene acetate | bazedoxifene acetate results in increased expression of AREG mRNA | increases expression | 19022889 |
| D001572 | Benzofurans | Benzofurans analog results in increased expression of AREG mRNA | increases expression | 16929009 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in increased expression of AREG mRNA | increases expression | 19181443 18061397 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in increased expression of AREG mRNA | increases expression | 16929009 |
| D015123 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of AREG mRNA | increases expression | 19150397 20382639 |
| C006780 | bisphenol A | bisphenol A results in increased expression of AREG mRNA | increases expression | 16474171 |
| D020122 | tert-Butylhydroperoxide | tert-Butylhydroperoxide results in increased expression of AREG mRNA | increases expression | 12414654 |
| C111332 | cis-1R-(4'-pyrrolidinoethoxyphenyl)-2S-phenyl-6-hydroxy-1,2,3,4-tetrahydronaphthalene, tartrate salt | cis-1R-(4'-pyrrolidinoethoxyphenyl)-2S-phenyl-6-hydroxy-1,2,3,4-tetrahydronaphthalene, tartrate salt inhibits the reaction [Estrogens, Conjugated (USP) results in increased expression of AREG mRNA] | decreases reaction|increases expression | 19022889 |
| C111332 | cis-1R-(4'-pyrrolidinoethoxyphenyl)-2S-phenyl-6-hydroxy-1,2,3,4-tetrahydronaphthalene, tartrate salt | cis-1R-(4'-pyrrolidinoethoxyphenyl)-2S-phenyl-6-hydroxy-1,2,3,4-tetrahydronaphthalene, tartrate salt results in increased expression of AREG mRNA | increases expression | 19022889 |
| D003513 | Cycloheximide | [Cycloheximide co-treated with Estradiol] results in increased expression of AREG mRNA | affects cotreatment|increases expression | 15072547 |
| D003513 | Cycloheximide | Cycloheximide results in increased expression of AREG mRNA | increases expression | 15072547 15228094 |
| C014347 | decitabine | decitabine results in increased expression of AREG mRNA | increases expression | 16367923 |
| D003840 | Deoxycholic Acid | Deoxycholic Acid results in increased secretion of AREG protein | increases secretion | 16213893 |
| D003907 | Dexamethasone | Dexamethasone results in decreased expression of AREG mRNA | decreases expression | 12837037 |
| D002117 | Calcitriol | Calcitriol results in increased expression of AREG mRNA | increases expression | 16002434 14996990 11237771 |
| D002117 | Calcitriol | Isotretinoin inhibits the reaction [Calcitriol results in increased expression of AREG mRNA] | decreases reaction|increases expression | 11237771 |
| D002117 | Calcitriol | Calcitriol results in increased expression of AREG mRNA | increases expression | 15509566 |
| D004958 | Estradiol | 4-hydroxy-N-desmethyltamoxifen inhibits the reaction [Estradiol results in increased expression of AREG mRNA] | decreases reaction|increases expression | 19244106 |
| D004958 | Estradiol | [Cycloheximide co-treated with Estradiol] results in increased expression of AREG mRNA | affects cotreatment|increases expression | 15072547 |
| D004958 | Estradiol | Estradiol results in increased expression of AREG mRNA | increases expression | 16257430 15072547 16474171 19244106 16514628 16202921 12432273 |
| D004958 | Estradiol | Valproic Acid promotes the reaction [Estradiol results in increased expression of AREG mRNA] | increases expression|increases reaction | 19772891 |
| D004958 | Estradiol | Estradiol results in increased expression of AREG mRNA | increases expression | 19022889 |
| D004967 | Estrogens | Estrogens affects the expression of AREG mRNA | affects expression | 15473135 |
| D004967 | Estrogens | Estrogens affects the expression of AREG mRNA | affects expression | 15473135 |
| D004966 | Estrogens, Conjugated (USP) | bazedoxifene acetate inhibits the reaction [Estrogens, Conjugated (USP) results in increased expression of AREG mRNA] | decreases reaction|increases expression | 19022889 |
| D004966 | Estrogens, Conjugated (USP) | cis-1R-(4'-pyrrolidinoethoxyphenyl)-2S-phenyl-6-hydroxy-1,2,3,4-tetrahydronaphthalene, tartrate salt inhibits the reaction [Estrogens, Conjugated (USP) results in increased expression of AREG mRNA] | decreases reaction|increases expression | 19022889 |
| D004966 | Estrogens, Conjugated (USP) | Estrogens, Conjugated (USP) results in increased expression of AREG mRNA | increases expression | 19022889 |
| D004966 | Estrogens, Conjugated (USP) | Raloxifene inhibits the reaction [Estrogens, Conjugated (USP) results in increased expression of AREG mRNA] | decreases reaction|increases expression | 19022889 |
| D005047 | Etoposide | Etoposide results in increased expression of AREG mRNA | increases expression | 15228094 |
| D005047 | Etoposide | Etoposide results in increased expression of AREG protein | increases expression | 15228094 |
| C056516 | exemestane | exemestane results in increased expression of AREG mRNA | increases expression | 18677558 |
| D015073 | 2-Acetylaminofluorene | 2-Acetylaminofluorene results in increased expression of AREG mRNA | increases expression | 17317680 |
| D015073 | 2-Acetylaminofluorene | TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of AREG mRNA] | affects reaction|increases expression | 17317680 |
| D005472 | Fluorouracil | AREG affects the susceptibility to Fluorouracil | affects response to substance | 15067352 |
| D005472 | Fluorouracil | Fluorouracil results in increased expression of AREG mRNA | increases expression | 16709241 |
| D005576 | Forskolin | Forskolin results in increased expression of AREG mRNA | increases expression | 15313392 15284208 15967414 15474502 |
| D005576 | Forskolin | N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Forskolin results in increased expression of AREG mRNA] | decreases reaction|increases expression | 15967414 |
| D005576 | Forskolin | N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Forskolin results in increased expression of AREG protein] | decreases reaction|increases expression | 15967414 |
| C070081 | fulvestrant | fulvestrant results in decreased expression of AREG mRNA | decreases expression | 16514628 16202921 |
| C070081 | fulvestrant | fulvestrant results in increased expression of AREG mRNA | increases expression | 15072547 |
| C419708 | gefitinib | AREG protein results in decreased susceptibility to gefitinib | decreases response to substance | 15496427 16230376 |
| C419708 | gefitinib | gefitinib inhibits the reaction [irinotecan metabolite results in increased expression of AREG mRNA] | decreases reaction|increases expression | 15723263 |
| C419708 | gefitinib | gefitinib inhibits the reaction [irinotecan results in increased expression of AREG mRNA] | decreases reaction|increases expression | 15723263 |
| D019833 | Genistein | Genistein results in increased expression of AREG mRNA | increases expression | 16474171 |
| D006064 | Gonadotropins, Equine | [Gonadotropins, Equine co-treated with Chorionic Gonadotropin] results in increased expression of AREG mRNA | affects cotreatment|increases expression | 15831568 |
| D006064 | Gonadotropins, Equine | Gonadotropins, Equine results in increased expression of AREG mRNA | increases expression | 15291759 |
| D006063 | Chorionic Gonadotropin | [Gonadotropins, Equine co-treated with Chorionic Gonadotropin] results in increased expression of AREG mRNA | affects cotreatment|increases expression | 15831568 |
| D006851 | Hydrochloric Acid | Hydrochloric Acid results in decreased expression of AREG mRNA | decreases expression | 15046208 |
| D006861 | Hydrogen Peroxide | Hydrogen Peroxide results in increased expression of AREG mRNA | increases expression | 12414654 |
| C475919 | hydroxytamoxifen | hydroxytamoxifen results in increased expression of AREG mRNA | increases expression | 15072547 |
| C075954 | indolo(3,2-b)carbazole | indolo(3,2-b)carbazole results in increased expression of AREG mRNA | increases expression | 18061397 |
| C051890 | irinotecan | gefitinib inhibits the reaction [irinotecan metabolite results in increased expression of AREG mRNA] | decreases reaction|increases expression | 15723263 |
| C051890 | irinotecan | gefitinib inhibits the reaction [irinotecan results in increased expression of AREG mRNA] | decreases reaction|increases expression | 15723263 |
| C051890 | irinotecan | irinotecan metabolite results in increased expression of AREG mRNA | increases expression | 15723263 |
| C051890 | irinotecan | irinotecan results in increased expression of AREG mRNA | increases expression | 15723263 |
| D015056 | 1-Methyl-3-isobutylxanthine | 1-Methyl-3-isobutylxanthine results in increased expression of AREG mRNA | increases expression | 15284208 |
| C107086 | KB R7785 | KB R7785 inhibits the reaction [IL8 protein results in increased cleavage of and results in increased secretion of AREG protein] | decreases reaction|increases cleavage|increases secretion | 15300588 |
| C039993 | loxtidine | loxtidine results in decreased expression of AREG mRNA | decreases expression | 15940630 |
| C039993 | loxtidine | [YF 476 co-treated with loxtidine] results in decreased expression of AREG mRNA | affects cotreatment|decreases expression | 15940630 |
| C100342 | marimastat | marimastat inhibits the reaction [GRP protein results in increased cleavage of and results in increased secretion of AREG protein] | decreases reaction|increases cleavage|increases secretion | 15342401 |
| D008748 | Methylcholanthrene | Methylcholanthrene results in increased expression of AREG mRNA | increases expression | 16257430 |
| C063509 | N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide | N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Forskolin results in increased expression of AREG mRNA] | decreases reaction|increases expression | 15967414 |
| C063509 | N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide | N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Forskolin results in increased expression of AREG protein] | decreases reaction|increases expression | 15967414 |
| C063509 | N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide | N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [FSHB protein results in increased expression of AREG mRNA] | decreases reaction|increases expression | 15967414 |
| C063509 | N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide | N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [FSHB protein results in increased expression of AREG protein] | decreases reaction|increases expression | 15967414 |
| C063509 | N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide | N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [LHB protein results in increased expression of AREG mRNA] | decreases reaction|increases expression | 15967414 |
| C063509 | N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide | N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [LHB protein results in increased expression of AREG protein] | decreases reaction|increases expression | 15967414 |
| C014707 | nitrosobenzylmethylamine | nitrosobenzylmethylamine results in increased expression of AREG mRNA | increases expression | 17616710 |
| D010126 | Ozone | Ozone results in increased expression of AREG mRNA | increases expression | 17095637 19555225 |
| D010126 | Ozone | TTPA protein affects the reaction [Ozone results in increased expression of AREG mRNA] | affects reaction|increases expression | 19555225 |
| D010126 | Ozone | Ozone results in increased expression of AREG mRNA | increases expression | 16716893 |
| C093973 | PD 98059 | PD 98059 results in decreased activity of AREG protein | decreases activity | 12589827 |
| D010656 | Phenylephrine | Phenylephrine results in increased expression of AREG mRNA | increases expression | 18158353 |
| C006253 | pirinixic acid | pirinixic acid results in increased expression of AREG mRNA | increases expression | 17426115 |
| D010936 | Plant Extracts | Plant Extracts results in increased expression of AREG mRNA | increases expression | 18061397 |
| D011078 | Polychlorinated Biphenyls | Polychlorinated Biphenyls analog results in increased expression of AREG mRNA | increases expression | 16474171 |
| D011374 | Progesterone | [Progesterone affects the activity of PGR protein alternative form] which affects the expression of AREG mRNA | affects activity|affects expression | 15866122 |
| D011374 | Progesterone | Progesterone results in increased expression of AREG mRNA | increases expression | 18070364 |
| D011374 | Progesterone | Progesterone affects the expression of AREG | affects expression | 16794005 15178747 |
| D015232 | Dinoprostone | Dinoprostone results in increased expression of AREG mRNA | increases expression | 15284208 |
| D015232 | Dinoprostone | Dinoprostone results in increased expression of AREG mRNA | increases expression | 15509566 |
| D015232 | Dinoprostone | Dinoprostone promotes the reaction [CREB1 protein binds to AREG promoter] | affects binding|increases reaction | 16088955 |
| D015232 | Dinoprostone | Dinoprostone results in increased expression of AREG mRNA | increases expression | 16088955 |
| D020849 | Raloxifene | [Raloxifene co-treated with ESR2 protein] results in increased expression of AREG mRNA | affects cotreatment|increases expression | 19059307 |
| D020849 | Raloxifene | Raloxifene results in decreased expression of AREG mRNA | decreases expression | 16514628 |
| D020849 | Raloxifene | Raloxifene inhibits the reaction [Estrogens, Conjugated (USP) results in increased expression of AREG mRNA] | decreases reaction|increases expression | 19022889 |
| D020849 | Raloxifene | Raloxifene results in increased expression of AREG mRNA | increases expression | 19022889 |
| D012172 | Retinaldehyde | Retinaldehyde results in increased expression of AREG mRNA | increases expression | 16470170 |
| D015474 | Isotretinoin | Isotretinoin inhibits the reaction [Calcitriol results in increased expression of AREG mRNA] | decreases reaction|increases expression | 11237771 |
| D020889 | Rolipram | Rolipram results in increased expression of AREG mRNA | increases expression | 15284208 |
| C093642 | SB 203580 | SB 203580 results in decreased activity of AREG protein | decreases activity | 12589827 |
| C017947 | sodium arsenite | sodium arsenite results in increased expression of AREG mRNA | increases expression | 16014739 |
| D019311 | Staurosporine | Staurosporine inhibits the reaction [GAST protein results in increased secretion of AREG protein] | decreases reaction|increases secretion | 15474551 |
| D019311 | Staurosporine | Staurosporine inhibits the reaction [IL1B protein results in increased secretion of AREG protein] | decreases reaction|increases secretion | 15474551 |
| C416927 | SU 6656 | SU 6656 results in decreased secretion of AREG protein | decreases secretion | 15615697 |
| C025462 | sulindac sulfide | sulindac sulfide results in increased expression of AREG mRNA | increases expression | 16184548 |
| D013629 | Tamoxifen | [Tamoxifen co-treated with ESR2 protein] results in increased expression of AREG mRNA | affects cotreatment|increases expression | 19059307 |
| D013629 | Tamoxifen | Tamoxifen results in increased expression of AREG mRNA | increases expression | 16202921 |
| C004648 | testosterone enanthate | testosterone enanthate affects the expression of AREG mRNA | affects expression | 17440010 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in increased expression of AREG mRNA | increases expression | 18061397 16704738 |
| D013749 | Tetrachlorodibenzodioxin | AHR protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of AREG mRNA] | affects reaction|increases expression | 16929009 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in increased expression of AREG mRNA | increases expression | 16929009 |
| C496197 | trans-10,cis-12-conjugated linoleic acid | trans-10,cis-12-conjugated linoleic acid results in increased expression of AREG mRNA | increases expression | 17951470 |
| D014212 | Tretinoin | Tretinoin results in increased expression of AREG mRNA | increases expression | 16470170 |
| D014212 | Tretinoin | Tretinoin results in increased expression of AREG protein | increases expression | 16470170 |
| C101044 | tyrphostin AG 1478 | tyrphostin AG 1478 results in decreased activity of AREG protein | decreases activity | 15706222 |
| C113580 | U 0126 | U 0126 results in decreased secretion of AREG protein | decreases secretion | 15615697 |
| D014635 | Valproic Acid | Valproic Acid promotes the reaction [Estradiol results in increased expression of AREG mRNA] | increases expression|increases reaction | 19772891 |
| D024483 | Vitamin K 3 | Vitamin K 3 results in increased expression of AREG mRNA | increases expression | 12414654 |
| C009687 | wortmannin | wortmannin results in decreased activity of AREG protein | decreases activity | 12589827 |
| C104428 | YF 476 | [YF 476 co-treated with loxtidine] results in decreased expression of AREG mRNA | affects cotreatment|decreases expression | 15940630 |
| C104428 | YF 476 | YF 476 results in decreased expression of AREG mRNA | decreases expression | 15940630 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000008 | Abdominal Neoplasms | Tamoxifen | 3.80 | 14745880 | |
| MESH:D000014 | Abnormalities, Drug-Induced | Isotretinoin | 10.16 | 18769834 | |
| MESH:D000014 | Abnormalities, Drug-Induced | Tetrachlorodibenzodioxin | 10.16 | 14514962 15322242 11752688 | |
| MESH:D000014 | Abnormalities, Drug-Induced | Valproic Acid | 10.16 | 8875741 | |
| MESH:D000015 | Abnormalities, Multiple | Isotretinoin | 8.21 | 18769834 | |
| MESH:D000015 | Abnormalities, Multiple | Valproic Acid | 8.21 | 19490988 | |
| MESH:D000138 | Acidosis | Ammonium Chloride | 8.30 | 18287403 | |
| MESH:D000138 | Acidosis | Hydrochloric Acid | 8.30 | 12771618 15920416 19262391 11574821 16144966 20872349 | |
| MESH:D000141 | Acidosis, Renal Tubular | Hydrochloric Acid | 5.05 | 17183249 | |
| MESH:D000142 | Acidosis, Respiratory | Hydrochloric Acid | 5.07 | 20597076 | |
| MESH:D017486 | Acneiform Eruptions | Isotretinoin | 5.54 | 16232082 | |
| MESH:D000152 | Acne Vulgaris | Isotretinoin | 4.73 | 16185265 18769834 | |
| MESH:D000168 | Acrocephalosyndactylia | U 0126 | 4.76 | 17694057 | |
| MESH:D055371 | Acute Lung Injury | Hydrochloric Acid | 7.07 | 19060228 19760209 16759491 19094174 15970105 11850527 11953099 | |
| MESH:D055371 | Acute Lung Injury | pirinixic acid | 7.07 | 18653653 | |
| MESH:D000230 | Adenocarcinoma | Benzo(a)pyrene | 8.04 | 20464547 20127859 | |
| MESH:D000230 | Adenocarcinoma | Estradiol | 8.04 | 11473722 | |
| MESH:D000230 | Adenocarcinoma | Fluorouracil | 8.04 | 17638652 | |
| MESH:D000230 | Adenocarcinoma | Genistein | 8.04 | 11473722 | |
| MESH:D000236 | Adenoma | 2-Acetylaminofluorene | 8.58 | 10737359 | |
| MESH:D000236 | Adenoma | Benzo(a)pyrene | 8.58 | 6695378 | |
| MESH:D000236 | Adenoma | Methylcholanthrene | 8.58 | 10545420 6695378 | |
| MESH:D002759 | Adenoma, Bile Duct | 2-Acetylaminofluorene | 5.26 | 6705139 | |
| MESH:D018248 | Adenoma, Liver Cell | pirinixic acid | 7.48 | 16434500 | |
| MESH:D018248 | Adenoma, Liver Cell | Tetrachlorodibenzodioxin | 7.48 | 16835633 | |
| MESH:D011125 | Adenomatous Polyposis Coli | Dinoprostone | 4.38 | 17942926 | |
| MESH:D000310 | Adrenal Gland Neoplasms | sodium arsenite | 3.95 | 15276417 | |
| MESH:D018246 | Adrenocortical Adenoma | Arsenic | 11.31 | 17306315 | |
| MESH:D018246 | Adrenocortical Adenoma | sodium arsenite | 11.31 | 17306315 16712894 | |
| MESH:D000419 | Albuminuria | Raloxifene | 3.90 | 17308373 17451421 | |
| MESH:D000505 | Alopecia | Tretinoin | 3.02 | 15955085 | |
| MESH:D000544 | Alzheimer Disease | Ozone | 7.53 | 15513908 | |
| MESH:D000544 | Alzheimer Disease | Plant Extracts | 7.53 | 16962711 | |
| MESH:D000544 | Alzheimer Disease | Raloxifene | 7.53 | 15800139 | |
| MESH:D000544 | Alzheimer Disease | sulindac sulfide | 7.53 | 18759972 | |
| MESH:D000550 | Amblyopia | Valproic Acid | 4.48 | 17688650 | |
| MESH:D000740 | Anemia | Fluorouracil | 6.54 | 16511603 17963324 15504547 | |
| MESH:D000740 | Anemia | Tetrachlorodibenzodioxin | 6.54 | 11748828 | |
| MESH:D000799 | Angioedema | Acetaminophen | 3.10 | 10982225 | |
| MESH:D000860 | Anoxia | Hydrochloric Acid | 4.57 | 15090967 | |
| MESH:D001008 | Anxiety Disorders | Valproic Acid | 2.98 | 17497229 | |
| MESH:D001014 | Aortic Aneurysm | Dinoprostone | 4.91 | 10231640 | |
| MESH:D017544 | Aortic Aneurysm, Abdominal | Benzo(a)pyrene | 9.61 | 19183758 | |
| MESH:D017544 | Aortic Aneurysm, Abdominal | Dinoprostone | 9.61 | 10388637 | |
| MESH:D001145 | Arrhythmias, Cardiac | Phenylephrine | 3.47 | 17460149 | |
| MESH:D020261 | Arsenic Poisoning | Arsenic | 2.61 | 12569548 18414634 16251483 16835338 | |
| MESH:D001169 | Arthritis, Experimental | Dexamethasone | 9.56 | 17659584 | |
| MESH:D001169 | Arthritis, Experimental | Plant Extracts | 9.56 | 14686799 | |
| MESH:D001169 | Arthritis, Experimental | Tretinoin | 9.56 | 16412693 | |
| MESH:D001172 | Arthritis, Rheumatoid | Ozone | 3.86 | 15570426 | |
| MESH:D001172 | Arthritis, Rheumatoid | Tretinoin | 3.86 | 16292516 | |
| MESH:D001249 | Asthma | marker/mechanism | 15696081 | ||
| MESH:D001249 | Asthma | Ozone | 3.98 | 16373670 17854713 | |
| MESH:D001249 | Asthma | Tretinoin | 3.98 | 16456186 | |
| MESH:D050197 | Atherosclerosis | Arsenic | 5.35 | 12928151 19371607 | |
| MESH:D050197 | Atherosclerosis | Methylcholanthrene | 5.35 | 11922910 | |
| MESH:D001284 | Atrophy | fulvestrant | 4.15 | 11514358 | |
| MESH:D001321 | Autistic Disorder | Acetaminophen | 1.88 | 18445737 | |
| MESH:D001321 | Autistic Disorder | Valproic Acid | 1.88 | 18396377 18775368 19232924 16609825 19460635 18940202 18316065 20603192 17157402 18985861 17507914 18558336 17688650 15238991 18177632 | |
| MESH:D001471 | Barrett Esophagus | Tretinoin | 3.70 | 16935849 | |
| MESH:D001477 | Bartter Syndrome | Dinoprostone | 5.02 | 15976003 | |
| MESH:D001714 | Bipolar Disorder | Valproic Acid | 2.65 | 17594078 20046352 | |
| MESH:D001778 | Blood Coagulation Disorders | Hydrochloric Acid | 16.59 | 15920416 | |
| MESH:D001778 | Blood Coagulation Disorders | pirinixic acid | 16.59 | 19483382 | |
| MESH:D001778 | Blood Coagulation Disorders | Tetrachlorodibenzodioxin | 16.59 | 12125929 | |
| MESH:D001778 | Blood Coagulation Disorders | Tretinoin | 16.59 | 16206674 16197459 | |
| MESH:D001836 | Body Weight Changes | Tetrachlorodibenzodioxin | 3.04 | 15340226 | |
| MESH:D001848 | Bone Diseases, Developmental | Tetrachlorodibenzodioxin | 6.31 | 15746008 | |
| MESH:D001848 | Bone Diseases, Developmental | Valproic Acid | 6.31 | 8888407 | |
| MESH:D019046 | Bone Marrow Neoplasms | Etoposide | 4.42 | 14601052 | |
| MESH:D001862 | Bone Resorption | bisphenol A | 3.20 | 11985600 | |
| MESH:D001919 | Bradycardia | Phenylephrine | 3.82 | 15306635 | |
| MESH:D020201 | Brain Hemorrhage, Traumatic | Progesterone | 4.59 | 17868700 | |
| MESH:D001930 | Brain Injuries | Progesterone | 8.59 | 15665606 15380490 15845082 | |
| MESH:D001930 | Brain Injuries | Raloxifene | 8.59 | 16580743 | |
| MESH:D002545 | Brain Ischemia | Plant Extracts | 4.00 | 16041641 | |
| MESH:D001943 | Breast Neoplasms | therapeutic | 11237771 | ||
| MESH:D001943 | Breast Neoplasms | Benzo(a)pyrene | 13.60 | 17474063 20146248 | |
| MESH:D001943 | Breast Neoplasms | bisphenol A | 13.60 | 17123778 | |
| MESH:D001943 | Breast Neoplasms | Calcitriol | 13.60 | 11237771 | |
| MESH:D001943 | Breast Neoplasms | decitabine | 13.60 | 18320071 19208741 | |
| MESH:D001943 | Breast Neoplasms | Estradiol | 13.60 | 17018787 19861407 18497071 16675129 14630087 12948864 17261762 17289903 | |
| MESH:D001943 | Breast Neoplasms | Etoposide | 13.60 | 16322251 | |
| MESH:D001943 | Breast Neoplasms | exemestane | 13.60 | 16002280 17892469 17952589 | |
| MESH:D001943 | Breast Neoplasms | Fluorouracil | 13.60 | 19217205 15136595 18357371 16110121 16595493 18608205 16557594 | |
| MESH:D001943 | Breast Neoplasms | fulvestrant | 13.60 | 18984771 | |
| MESH:D001943 | Breast Neoplasms | Genistein | 13.60 | 16873071 17200150 16541309 | |
| MESH:D001943 | Breast Neoplasms | Methylcholanthrene | 13.60 | 17474063 | |
| MESH:D001943 | Breast Neoplasms | Progesterone | 13.60 | 15562024 16175315 17614352 | |
| MESH:D001943 | Breast Neoplasms | Raloxifene | 13.60 | 17049068 15775269 17595753 17952589 17440819 17261762 17242785 15758505 16837676 15572757 17893378 16912660 | |
| MESH:D001943 | Breast Neoplasms | Tamoxifen | 13.60 | 19142967 19059307 18351453 17440819 19289846 19487384 19103187 16818667 20544844 19244106 16202921 19066611 18425577 17049068 20135344 20065188 18855134 21138602 15668708 18997820 19155303 18821012 20005174 18984771 11161223 19410462 19115204 19288272 15565566 16273361 18629630 20390343 21152245 17261762 17893378 17242785 19200415 18815881 19189212 19189210 19084267 20859285 19011961 19221464 16873071 | |
| MESH:D001943 | Breast Neoplasms | Tetrachlorodibenzodioxin | 13.60 | 20435547 | |
| MESH:D001943 | Breast Neoplasms | Tretinoin | 13.60 | 16443354 16873071 16166294 | |
| MESH:D016535 | Bronchial Hyperreactivity | Hydrochloric Acid | 11.02 | 12378975 | |
| MESH:D016535 | Bronchial Hyperreactivity | Ozone | 11.02 | 15516495 19059883 18315731 14754758 16777450 17626835 18417511 | |
| MESH:D016535 | Bronchial Hyperreactivity | tyrphostin AG 1478 | 11.02 | 12794006 | |
| MESH:D001986 | Bronchial Spasm | Hydrochloric Acid | 4.72 | 15578804 | |
| MESH:D001997 | Bronchopulmonary Dysplasia | Tretinoin | 3.86 | 16813970 | |
| MESH:D002057 | Burns, Chemical | Plant Extracts | 4.59 | 9625245 | |
| MESH:D002100 | Cachexia | Ozone | 4.01 | 16183385 | |
| MESH:D002181 | Candidiasis, Vulvovaginal | Estradiol | 3.73 | 16111702 | |
| MESH:D002276 | Carcinoid Tumor | Fluorouracil | 3.92 | 16051944 | |
| MESH:D002277 | Carcinoma | Fluorouracil | 10.53 | 17121937 | |
| MESH:D002277 | Carcinoma | Methylcholanthrene | 10.53 | 10545420 | |
| MESH:D002277 | Carcinoma | Tetrachlorodibenzodioxin | 10.53 | 16835633 | |
| MESH:D002280 | Carcinoma, Basal Cell | Arsenic | 3.13 | 15504454 17687452 | |
| MESH:D018270 | Carcinoma, Ductal, Breast | Tamoxifen | 3.79 | 19066611 | |
| MESH:D018236 | Carcinoma, Embryonal | Tretinoin | 4.41 | 16168501 | |
| MESH:D006528 | Carcinoma, Hepatocellular | 2,6-dinitrotoluene | 24.56 | 16705839 | |
| MESH:D006528 | Carcinoma, Hepatocellular | 2-Acetylaminofluorene | 24.56 | 3084413 10737359 17761372 3581430 6705139 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Acetaminophen | 24.56 | 3084413 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Arsenic | 24.56 | 17306315 16507464 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Estradiol | 24.56 | 16924424 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Estrogens | 24.56 | 15341023 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Fluorouracil | 24.56 | 18930000 16332177 16799960 17045692 17971768 17088986 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Genistein | 24.56 | 16924424 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Plant Extracts | 24.56 | 18834353 | |
| MESH:D006528 | Carcinoma, Hepatocellular | sodium arsenite | 24.56 | 17306315 16507464 15276417 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Tamoxifen | 24.56 | 16924424 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Tretinoin | 24.56 | 1917145 | |
| MESH:D002278 | Carcinoma in Situ | bisphenol A | 4.25 | 17123778 | |
| MESH:D002289 | Carcinoma, Non-Small-Cell Lung | marker/mechanism | 15496427 16230376 | ||
| MESH:D002289 | Carcinoma, Non-Small-Cell Lung | gefitinib | 5.21 | 16230376 18347146 15496427 20005069 19233551 17290066 | |
| MESH:D002289 | Carcinoma, Non-Small-Cell Lung | sulindac sulfide | 5.21 | 12391285 | |
| MESH:D002292 | Carcinoma, Renal Cell | Fluorouracil | 2.62 | 18695887 | |
| MESH:D002294 | Carcinoma, Squamous Cell | therapeutic | 11237771 | ||
| MESH:D002294 | Carcinoma, Squamous Cell | Arsenic | 20.96 | 15504454 18922899 17687452 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Benzo(a)pyrene | 20.96 | 20419170 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Calcitriol | 20.96 | 11237771 | |
| MESH:D002294 | Carcinoma, Squamous Cell | decitabine | 20.96 | 19215824 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Fluorouracil | 20.96 | 17066447 16280240 18986760 16757204 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Isotretinoin | 20.96 | 11237771 | |
| MESH:D002294 | Carcinoma, Squamous Cell | sodium arsenite | 20.96 | 18572023 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Tretinoin | 20.96 | 16051514 16096774 | |
| MESH:D002295 | Carcinoma, Transitional Cell | Arsenic | 12.19 | 18640142 | |
| MESH:D002295 | Carcinoma, Transitional Cell | Raloxifene | 12.19 | 17572228 | |
| MESH:D002295 | Carcinoma, Transitional Cell | Tamoxifen | 12.19 | 17572228 | |
| MESH:D006332 | Cardiomegaly | Phenylephrine | 8.86 | 17124262 17287366 15728586 16170337 11754973 11179087 | |
| MESH:D006332 | Cardiomegaly | Plant Extracts | 8.86 | 17645561 | |
| MESH:D006332 | Cardiomegaly | Tetrachlorodibenzodioxin | 8.86 | 16120746 18850075 18670907 | |
| MESH:D002318 | Cardiovascular Diseases | Arsenic | 12.92 | 17938729 15738583 19152805 | |
| MESH:D002318 | Cardiovascular Diseases | Genistein | 12.92 | 16332659 | |
| MESH:D002318 | Cardiovascular Diseases | Hydrogen Peroxide | 12.92 | 16936243 | |
| MESH:D002318 | Cardiovascular Diseases | Raloxifene | 12.92 | 15775269 | |
| MESH:D002340 | Carotid Artery Diseases | Arsenic | 3.68 | 16973168 18022660 | |
| MESH:D002386 | Cataract | Acetaminophen | 5.62 | 10977129 | |
| MESH:D002386 | Cataract | Tretinoin | 5.62 | 17460283 | |
| MESH:D002471 | Cell Transformation, Neoplastic | 2,6-dinitrotoluene | 19.41 | 6135515 | |
| MESH:D002471 | Cell Transformation, Neoplastic | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide | 19.41 | 20889678 | |
| MESH:D002471 | Cell Transformation, Neoplastic | Dinoprostone | 19.41 | 16192471 | |
| MESH:D002471 | Cell Transformation, Neoplastic | Estradiol | 19.41 | 18566989 | |
| MESH:D002471 | Cell Transformation, Neoplastic | Methylcholanthrene | 19.41 | 16192471 | |
| MESH:D002471 | Cell Transformation, Neoplastic | sodium arsenite | 19.41 | 19524636 20056578 | |
| MESH:D018290 | Cervical Intraepithelial Neoplasia | Tretinoin | 3.86 | 16129372 | |
| MESH:D002659 | Child Development Disorders, Pervasive | Valproic Acid | 2.39 | 20734317 | |
| MESH:D018281 | Cholangiocarcinoma | Tetrachlorodibenzodioxin | 2.53 | 16835633 | |
| MESH:D002779 | Cholestasis | pirinixic acid | 2.26 | 19176532 | |
| MESH:D002822 | Choriocarcinoma | Tretinoin | 4.41 | 16461808 | |
| MESH:D002972 | Cleft Palate | Tetrachlorodibenzodioxin | 4.52 | 15340226 8697196 12621046 16354765 15668235 | |
| MESH:D002972 | Cleft Palate | Tretinoin | 4.52 | 9407595 | |
| MESH:D003072 | Cognition Disorders | Raloxifene | 3.90 | 15800139 | |
| MESH:D003092 | Colitis | Tretinoin | 3.00 | 17035595 | |
| MESH:D003110 | Colonic Neoplasms | decitabine | 11.39 | 17616700 | |
| MESH:D003110 | Colonic Neoplasms | Deoxycholic Acid | 11.39 | 16213893 | |
| MESH:D003110 | Colonic Neoplasms | Dexamethasone | 11.39 | 15824018 | |
| MESH:D003110 | Colonic Neoplasms | Fluorouracil | 11.39 | 17169374 16510598 17016597 15001691 17018589 18772588 17287894 17725105 16340194 17172411 | |
| MESH:D003110 | Colonic Neoplasms | Genistein | 11.39 | 17182828 | |
| MESH:D003110 | Colonic Neoplasms | irinotecan | 11.39 | 17287894 17725105 | |
| MESH:D015179 | Colorectal Neoplasms | decitabine | 5.32 | 18981723 | |
| MESH:D015179 | Colorectal Neoplasms | Fluorouracil | 5.32 | 18509181 18448328 18288408 16391804 18383874 17695437 17594712 16524972 17454858 16282729 17094418 17401013 18949393 20501625 17016601 16331619 15289873 18802399 17255274 15148649 14970324 16303861 | |
| MESH:D015179 | Colorectal Neoplasms | gefitinib | 5.32 | 17594712 | |
| MESH:D015179 | Colorectal Neoplasms | irinotecan | 5.32 | 15273666 16391804 17159606 18259882 17454858 18509181 16303861 | |
| MESH:D015179 | Colorectal Neoplasms | Polychlorinated Biphenyls | 5.32 | 15531428 | |
| MESH:D000013 | Congenital Abnormalities | Tetrachlorodibenzodioxin | 2.43 | 17141729 14669216 | |
| MESH:D019465 | Craniofacial Abnormalities | Dexamethasone | 5.98 | 17728286 | |
| MESH:D019465 | Craniofacial Abnormalities | Isotretinoin | 5.98 | 18769834 9879862 | |
| MESH:D019465 | Craniofacial Abnormalities | Tetrachlorodibenzodioxin | 5.98 | 20055451 10048152 15322242 | |
| MESH:D019465 | Craniofacial Abnormalities | Tretinoin | 5.98 | 8800419 16925845 10589399 14991402 17551590 9664655 9142499 9211117 9224671 9125849 | |
| MESH:D019465 | Craniofacial Abnormalities | Valproic Acid | 5.98 | 17688650 8888407 16575769 | |
| MESH:D016638 | Critical Illness | Estrogens | 5.21 | 16670151 | |
| MESH:D003490 | Cyanosis | 2,6-dinitrotoluene | 3.30 | 18551238 | |
| MESH:D003556 | Cystitis | Hydrochloric Acid | 10.08 | 20719367 12599022 19279288 12853844 | |
| MESH:D003556 | Cystitis | Rolipram | 10.08 | 18710439 | |
| MESH:D018856 | Cystitis, Interstitial | Hydrochloric Acid | 5.07 | 17714534 | |
| MESH:D007644 | Darier Disease | Fluorouracil | 4.06 | 16733453 | |
| MESH:D003704 | Dementia | Polychlorinated Biphenyls | 4.04 | 16140633 | |
| MESH:D003711 | Demyelinating Diseases | Tamoxifen | 3.64 | 19031437 | |
| MESH:D003865 | Depressive Disorder, Major | Raloxifene | 3.53 | 17474826 | |
| MESH:D003872 | Dermatitis | Rolipram | 5.37 | 16442096 | |
| MESH:D017449 | Dermatitis, Allergic Contact | Dexamethasone | 2.75 | 12438553 | |
| MESH:D003876 | Dermatitis, Atopic | pirinixic acid | 2.03 | 18249437 | |
| MESH:D003924 | Diabetes Mellitus, Type 2 | Genistein | 3.51 | 16647724 | |
| MESH:D003924 | Diabetes Mellitus, Type 2 | Tetrachlorodibenzodioxin | 3.51 | 17107852 | |
| MESH:D003928 | Diabetic Nephropathies | Estradiol | 16.31 | 19279558 | |
| MESH:D003928 | Diabetic Nephropathies | Plant Extracts | 16.31 | 19706694 | |
| MESH:D003928 | Diabetic Nephropathies | Raloxifene | 16.31 | 17451421 15920148 17308373 | |
| MESH:D003928 | Diabetic Nephropathies | Tamoxifen | 16.31 | 19279558 | |
| MESH:D003929 | Diabetic Neuropathies | Progesterone | 3.78 | 17187935 | |
| MESH:D003967 | Diarrhea | Dexamethasone | 6.27 | 7237001 | |
| MESH:D003967 | Diarrhea | Dinoprostone | 6.27 | 7237001 11488427 10446763 | |
| MESH:D056486 | Drug-Induced Liver Injury | 2,6-dinitrotoluene | 6.56 | 21346803 18551238 | |
| MESH:D056486 | Drug-Induced Liver Injury | Acetaminophen | 6.56 | 16227642 11287661 16485898 17906064 16393943 19739265 12958197 12153990 19370779 10663392 11421492 10915739 16109766 12705907 15968718 16781746 16081117 14725611 17562736 11743745 11461765 2444490 19416960 19923254 11834606 18713872 18071297 19420014 19085960 12540782 16177239 19164858 10774834 12594235 14986274 12392966 17522070 11529661 14550746 15619225 11739529 | |
| MESH:D056486 | Drug-Induced Liver Injury | Tetrachlorodibenzodioxin | 6.56 | 20420201 | |
| MESH:D056486 | Drug-Induced Liver Injury | Valproic Acid | 6.56 | 1733752 19641884 | |
| MESH:D056487 | Drug-Induced Liver Injury, Chronic | Acetaminophen | 3.35 | 19426721 | |
| MESH:D004362 | Drug Toxicity | Tetrachlorodibenzodioxin | 2.20 | 11462148 | |
| MESH:D004421 | Dystonia | Valproic Acid | 3.37 | 1851702 | |
| MESH:D004485 | Eczema | Dexamethasone | 3.76 | 12438553 | |
| MESH:D004487 | Edema | Dexamethasone | 18.62 | 19703484 | |
| MESH:D004487 | Edema | pirinixic acid | 18.62 | 12083418 | |
| MESH:D004487 | Edema | Plant Extracts | 18.62 | 12787963 | |
| MESH:D004487 | Edema | Raloxifene | 18.62 | 15860553 | |
| MESH:D004487 | Edema | Staurosporine | 18.62 | 8273558 | |
| MESH:D004487 | Edema | Tetrachlorodibenzodioxin | 18.62 | 12711302 11000095 | |
| MESH:D004489 | Edema, Cardiac | Tetrachlorodibenzodioxin | 9.46 | 15322242 16714409 18230668 | |
| MESH:D004489 | Edema, Cardiac | Tretinoin | 9.46 | 18230668 | |
| MESH:D004681 | Encephalomyelitis, Autoimmune, Experimental | Calcitriol | 16.28 | 15138306 | |
| MESH:D004681 | Encephalomyelitis, Autoimmune, Experimental | Progesterone | 16.28 | 17692515 | |
| MESH:D004681 | Encephalomyelitis, Autoimmune, Experimental | Raloxifene | 16.28 | 15845917 | |
| MESH:D004681 | Encephalomyelitis, Autoimmune, Experimental | Tamoxifen | 16.28 | 19031437 | |
| MESH:D004701 | Endocrine Gland Neoplasms | decitabine | 4.37 | 19294695 | |
| MESH:D004714 | Endometrial Hyperplasia | Genistein | 3.86 | 16402032 | |
| MESH:D016889 | Endometrial Neoplasms | 4-hydroxytamoxifen | 17.86 | 19148513 | |
| MESH:D016889 | Endometrial Neoplasms | Estradiol | 17.86 | 18566989 11473722 19148513 | |
| MESH:D016889 | Endometrial Neoplasms | Genistein | 17.86 | 11473722 | |
| MESH:D016889 | Endometrial Neoplasms | Tamoxifen | 17.86 | 19155303 17893378 20544844 16202921 | |
| MESH:D016889 | Endometrial Neoplasms | Tretinoin | 17.86 | 16569247 | |
| MESH:D004715 | Endometriosis | Progesterone | 6.79 | 16134523 | |
| MESH:D004715 | Endometriosis | Tetrachlorodibenzodioxin | 6.79 | 10568697 9294722 | |
| MESH:D004719 | Endomyocardial Fibrosis | Plant Extracts | 4.93 | 15268973 | |
| MESH:D004831 | Epilepsies, Myoclonic | Valproic Acid | 3.44 | 3659116 17275665 | |
| MESH:D004828 | Epilepsies, Partial | Valproic Acid | 3.18 | 16628512 3922381 | |
| MESH:D004827 | Epilepsy | Plant Extracts | 5.52 | 19439326 19700373 | |
| MESH:D004827 | Epilepsy | Valproic Acid | 5.52 | 18234410 20417680 | |
| MESH:D004832 | Epilepsy, Absence | Valproic Acid | 2.96 | 6254150 7562514 6426943 | |
| MESH:D017029 | Epilepsy, Complex Partial | Valproic Acid | 3.58 | 7750514 | |
| MESH:D004830 | Epilepsy, Tonic-Clonic | Valproic Acid | 3.34 | 3659116 | |
| MESH:D004935 | Esophageal Diseases | Hydrochloric Acid | 5.06 | 19566590 | |
| MESH:D004938 | Esophageal Neoplasms | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide | 8.23 | 20426865 | |
| MESH:D004938 | Esophageal Neoplasms | Benzo(a)pyrene | 8.23 | 16530937 | |
| MESH:D004938 | Esophageal Neoplasms | Fluorouracil | 8.23 | 16481741 17638652 15173087 16785472 16337965 | |
| MESH:D004938 | Esophageal Neoplasms | nitrosobenzylmethylamine | 8.23 | 15547733 16704527 16510608 16805852 15623463 15150132 15264214 15878914 15547721 | |
| MESH:D004941 | Esophagitis | Hydrochloric Acid | 5.26 | 12928072 | |
| MESH:D004942 | Esophagitis, Peptic | Hydrochloric Acid | 5.27 | 11346197 14621274 20516732 | |
| MESH:D005124 | Eye Abnormalities | Tetrachlorodibenzodioxin | 6.93 | 11564622 | |
| MESH:D005124 | Eye Abnormalities | Tretinoin | 6.93 | 9664655 16938888 | |
| MESH:D005234 | Fatty Liver | pirinixic acid | 17.73 | 19236843 20131406 | |
| MESH:D005234 | Fatty Liver | Plant Extracts | 17.73 | 15975614 | |
| MESH:D005234 | Fatty Liver | Raloxifene | 17.73 | 17473493 | |
| MESH:D005234 | Fatty Liver | Tamoxifen | 17.73 | 19224547 14986274 | |
| MESH:D005234 | Fatty Liver | Valproic Acid | 17.73 | 19224547 14986274 | |
| MESH:D052776 | Female Urogenital Diseases | Tamoxifen | 2.74 | 16709447 | |
| MESH:D005313 | Fetal Death | Tetrachlorodibenzodioxin | 2.74 | 11858732 | |
| MESH:D005315 | Fetal Diseases | Valproic Acid | 4.14 | 16575769 | |
| MESH:D005317 | Fetal Growth Retardation | Valproic Acid | 3.43 | 18558336 8888407 | |
| MESH:D005334 | Fever | Dinoprostone | 4.23 | 16997862 11852909 | |
| MESH:D018221 | Fibromatosis, Abdominal | Tamoxifen | 3.79 | 14745880 | |
| MESH:D018222 | Fibromatosis, Aggressive | Tamoxifen | 3.45 | 19069698 | |
| MESH:D005354 | Fibrosarcoma | Methylcholanthrene | 4.21 | 10962813 14633661 | |
| MESH:D005355 | Fibrosis | Hydrochloric Acid | 10.82 | 18497604 | |
| MESH:D005355 | Fibrosis | Tetrachlorodibenzodioxin | 10.82 | 20067830 | |
| MESH:D005355 | Fibrosis | Tretinoin | 10.82 | 17994277 | |
| MESH:D005534 | Foot Diseases | Arsenic | 4.81 | 6392382 | |
| MESH:D005739 | Gas Poisoning | Hydrochloric Acid | 4.72 | 12378975 | |
| MESH:D005756 | Gastritis | Acetaminophen | 2.93 | 16983495 | |
| MESH:D005764 | Gastroesophageal Reflux | Hydrochloric Acid | 4.63 | 20516732 19951613 12212954 19957777 20545468 20616304 | |
| MESH:D005833 | Genital Neoplasms, Female | sodium arsenite | 3.95 | 16452187 | |
| MESH:D005909 | Glioblastoma | Genistein | 5.49 | 16598420 | |
| MESH:D005909 | Glioblastoma | Tretinoin | 5.49 | 17312396 | |
| MESH:D005910 | Glioma | Fluorouracil | 2.52 | 16145905 | |
| MESH:D006058 | Gonadal Disorders | Tetrachlorodibenzodioxin | 3.85 | 10696789 | |
| MESH:D006258 | Head and Neck Neoplasms | marker/mechanism | 15342401 | ||
| MESH:D006258 | Head and Neck Neoplasms | decitabine | 9.89 | 19215824 | |
| MESH:D006258 | Head and Neck Neoplasms | Fluorouracil | 9.89 | 18337622 15102660 15162350 | |
| MESH:D006258 | Head and Neck Neoplasms | Tretinoin | 9.89 | 16096774 | |
| MESH:D006317 | Hearing Loss, Noise-Induced | Tretinoin | 4.41 | 16084493 | |
| MESH:D006356 | Heartburn | Hydrochloric Acid | 5.06 | 19566590 | |
| MESH:D006330 | Heart Defects, Congenital | Benzo(a)pyrene | 8.51 | 20471113 | |
| MESH:D006330 | Heart Defects, Congenital | Tetrachlorodibenzodioxin | 8.51 | 11294989 10048152 | |
| MESH:D006330 | Heart Defects, Congenital | Tretinoin | 8.51 | 14991402 9664655 | |
| MESH:D006331 | Heart Diseases | Raloxifene | 3.00 | 11110106 | |
| MESH:D006333 | Heart Failure | pirinixic acid | 5.59 | 20558911 | |
| MESH:D006333 | Heart Failure | Plant Extracts | 5.59 | 18097624 | |
| MESH:D006390 | Hemangioendothelioma | 2-Acetylaminofluorene | 4.57 | 6705139 | |
| MESH:D006394 | Hemangiosarcoma | 2-Acetylaminofluorene | 3.75 | 6705139 | |
| MESH:D006470 | Hemorrhage | Tetrachlorodibenzodioxin | 2.67 | 11000095 | |
| MESH:D006529 | Hepatomegaly | pirinixic acid | 5.91 | 16221962 18467677 19176532 19772884 | |
| MESH:D006529 | Hepatomegaly | Tetrachlorodibenzodioxin | 5.91 | 12621046 16120746 15340226 | |
| MESH:D006548 | Hernia, Diaphragmatic | Dexamethasone | 2.76 | 7520565 | |
| MESH:D006558 | Herpes Genitalis | Estradiol | 4.28 | 15709030 | |
| MESH:D006561 | Herpes Simplex | Etoposide | 7.84 | 10809021 | |
| MESH:D006561 | Herpes Simplex | Plant Extracts | 7.84 | 10715843 | |
| MESH:D015658 | HIV Infections | Plant Extracts | 3.25 | 12878215 | |
| MESH:D019247 | HIV Wasting Syndrome | testosterone enanthate | 5.00 | 17440010 | |
| MESH:D006689 | Hodgkin Disease | Etoposide | 5.60 | 18180244 15147373 16200630 17606976 16135485 | |
| MESH:D006689 | Hodgkin Disease | sodium arsenite | 5.60 | 12676792 | |
| MESH:D019584 | Hot Flashes | Estradiol | 7.87 | 17088409 | |
| MESH:D019584 | Hot Flashes | Plant Extracts | 7.87 | 16566672 17454163 14716179 | |
| MESH:D006849 | Hydrocephalus | Valproic Acid | 4.13 | 17688650 | |
| MESH:D006869 | Hydronephrosis | Tetrachlorodibenzodioxin | 3.30 | 15340226 16959395 16354765 8697196 18606429 | |
| MESH:D006930 | Hyperalgesia | Acetaminophen | 9.73 | 16870215 | |
| MESH:D006930 | Hyperalgesia | Dinoprostone | 9.73 | 16793879 | |
| MESH:D006930 | Hyperalgesia | Tretinoin | 9.73 | 16870215 | |
| MESH:D006940 | Hyperemia | Hydrochloric Acid | 4.92 | 12646421 | |
| MESH:D017681 | Hypereosinophilic Syndrome | Tretinoin | 3.85 | 16778211 | |
| MESH:D006943 | Hyperglycemia | pirinixic acid | 2.54 | 20558911 | |
| MESH:D020138 | Hyperhomocysteinemia | Plant Extracts | 3.84 | 16484555 | |
| MESH:D017488 | Hyperkeratosis, Epidermolytic | Arsenic | 3.81 | 17050553 | |
| MESH:D006949 | Hyperlipidemias | Plant Extracts | 3.80 | 15268973 15975614 | |
| MESH:D006973 | Hypertension | Arsenic | 12.68 | 11953799 9931084 16076760 | |
| MESH:D006973 | Hypertension | Dexamethasone | 12.68 | 17042910 | |
| MESH:D006973 | Hypertension | Phenylephrine | 12.68 | 12717712 8949925 | |
| MESH:D006973 | Hypertension | Raloxifene | 12.68 | 17577099 15787275 | |
| MESH:D006973 | Hypertension | Tetrachlorodibenzodioxin | 12.68 | 18670907 18850075 | |
| MESH:D006975 | Hypertension, Portal | Hydrochloric Acid | 4.63 | 16984587 | |
| MESH:D006976 | Hypertension, Pulmonary | gefitinib | 7.07 | 18424623 | |
| MESH:D006976 | Hypertension, Pulmonary | Hydrochloric Acid | 7.07 | 19262391 | |
| MESH:D006984 | Hypertrophy | Phenylephrine | 3.89 | 12791704 18502941 | |
| MESH:D017380 | Hypertrophy, Right Ventricular | gefitinib | 5.50 | 18424623 | |
| MESH:D006987 | Hypesthesia | Arsenic | 4.81 | 16093927 | |
| MESH:D007022 | Hypotension | Hydrochloric Acid | 4.09 | 11574821 | |
| MESH:D007077 | Ileal Diseases | 1-Methyl-3-isobutylxanthine | 10.75 | 18306037 | |
| MESH:D007077 | Ileal Diseases | Rolipram | 10.75 | 18306037 | |
| MESH:D020244 | Infarction, Middle Cerebral Artery | Progesterone | 3.69 | 15869954 | |
| MESH:D007248 | Infertility, Male | decitabine | 8.35 | 17581917 | |
| MESH:D007248 | Infertility, Male | fulvestrant | 8.35 | 11514358 | |
| MESH:D007248 | Infertility, Male | sodium arsenite | 8.35 | 15346721 12646999 | |
| MESH:D007249 | Inflammation | Dexamethasone | 14.28 | 8960868 11099482 | |
| MESH:D007249 | Inflammation | Hydrochloric Acid | 14.28 | 11574821 | |
| MESH:D007249 | Inflammation | Plant Extracts | 14.28 | 16366677 15997105 12787963 19332304 | |
| MESH:D007249 | Inflammation | Progesterone | 14.28 | 15869954 | |
| MESH:D007249 | Inflammation | Tamoxifen | 14.28 | 19457130 | |
| MESH:D007249 | Inflammation | Tetrachlorodibenzodioxin | 14.28 | 12878042 12200463 | |
| MESH:D007333 | Insulin Resistance | bisphenol A | 9.30 | 16393666 | |
| MESH:D007333 | Insulin Resistance | Estradiol | 9.30 | 16393666 16627594 | |
| MESH:D007333 | Insulin Resistance | pirinixic acid | 9.30 | 16306350 | |
| MESH:D007410 | Intestinal Diseases | Hydrochloric Acid | 7.75 | 11574821 | |
| MESH:D007410 | Intestinal Diseases | Tretinoin | 7.75 | 17994277 | |
| MESH:D007414 | Intestinal Neoplasms | Plant Extracts | 3.97 | 12584176 12628509 12351151 | |
| MESH:D007569 | Jaw Abnormalities | Tetrachlorodibenzodioxin | 7.73 | 16580747 | |
| MESH:D007569 | Jaw Abnormalities | Tretinoin | 7.73 | 17551590 15992940 | |
| MESH:D007579 | Jejunal Diseases | 1-Methyl-3-isobutylxanthine | 10.75 | 18306037 | |
| MESH:D007579 | Jejunal Diseases | Rolipram | 10.75 | 18306037 | |
| MESH:D007642 | Keratosis | Arsenic | 4.26 | 12749816 16930632 | |
| MESH:D007674 | Kidney Diseases | Acetaminophen | 7.30 | 15629191 12587719 | |
| MESH:D007674 | Kidney Diseases | Estradiol | 7.30 | 15618244 | |
| MESH:D007674 | Kidney Diseases | sodium arsenite | 7.30 | 20008137 | |
| MESH:D007676 | Kidney Failure, Chronic | Hydrogen Peroxide | 3.61 | 16518626 | |
| MESH:D007680 | Kidney Neoplasms | 2,6-dinitrotoluene | 16.94 | 16705839 | |
| MESH:D007680 | Kidney Neoplasms | Estradiol | 16.94 | 15610895 | |
| MESH:D007680 | Kidney Neoplasms | Fluorouracil | 16.94 | 16985049 | |
| MESH:D007680 | Kidney Neoplasms | gefitinib | 16.94 | 18625569 | |
| MESH:D007680 | Kidney Neoplasms | Tamoxifen | 16.94 | 18625569 | |
| MESH:D007818 | Laryngeal Diseases | Hydrochloric Acid | 5.61 | 16498863 | |
| MESH:D007826 | Laryngismus | Hydrochloric Acid | 5.61 | 11510729 | |
| MESH:D007889 | Leiomyoma | Raloxifene | 3.81 | 16973256 | |
| MESH:D007938 | Leukemia | decitabine | 8.05 | 18980019 19235587 | |
| MESH:D007938 | Leukemia | Genistein | 8.05 | 17468513 18980019 | |
| MESH:D007938 | Leukemia | Tretinoin | 8.05 | 17143497 | |
| MESH:D007948 | Leukemia, Monocytic, Acute | PD 98059 | 9.66 | 16972261 | |
| MESH:D007948 | Leukemia, Monocytic, Acute | U 0126 | 9.66 | 16972261 | |
| MESH:D007951 | Leukemia, Myeloid | decitabine | 7.36 | 18454857 19117987 17236224 | |
| MESH:D007951 | Leukemia, Myeloid | Tretinoin | 7.36 | 16932348 16482212 19285840 | |
| MESH:D015470 | Leukemia, Myeloid, Acute | decitabine | 4.98 | 18206229 18704418 19387464 18460780 19010910 17679729 | |
| MESH:D015470 | Leukemia, Myeloid, Acute | Tretinoin | 4.98 | 17596541 19850784 16294345 | |
| MESH:D015470 | Leukemia, Myeloid, Acute | Valproic Acid | 4.98 | 17596541 16294345 | |
| MESH:D015477 | Leukemia, Myelomonocytic, Chronic | decitabine | 4.71 | 18055864 | |
| MESH:D015473 | Leukemia, Promyelocytic, Acute | Arsenic | 6.03 | 17339181 | |
| MESH:D015473 | Leukemia, Promyelocytic, Acute | Tretinoin | 6.03 | 19642359 19029980 17712046 17368321 16823087 16766008 17217047 15748426 17107899 12679006 17339181 16935935 16140955 16331271 17361223 17506722 9834237 19225113 17294898 17301526 19035177 16788101 19075265 16891316 17649720 | |
| MESH:D017880 | Limb Deformities, Congenital | Tretinoin | 2.75 | 9224671 | |
| MESH:D008064 | Lipidoses | Tamoxifen | 2.61 | 15342952 17567588 | |
| MESH:D008103 | Liver Cirrhosis | Hydrochloric Acid | 5.88 | 16984587 | |
| MESH:D008103 | Liver Cirrhosis | Plant Extracts | 5.88 | 17157831 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Dexamethasone | 15.00 | 16718785 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Dinoprostone | 15.00 | 15816358 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Estradiol | 15.00 | 14659978 14716833 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Genistein | 15.00 | 17823541 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | pirinixic acid | 15.00 | 15474484 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Plant Extracts | 15.00 | 15479170 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Retinaldehyde | 15.00 | 16248980 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Tamoxifen | 15.00 | 18564211 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Tetrachlorodibenzodioxin | 15.00 | 12878042 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Tretinoin | 15.00 | 16248980 18397230 | |
| MESH:D008107 | Liver Diseases | Acetaminophen | 7.32 | 16610002 12969438 16611625 19014921 12587719 11587558 19460945 19784758 | |
| MESH:D008107 | Liver Diseases | Arsenic | 7.32 | 11134558 | |
| MESH:D008107 | Liver Diseases | Dinoprostone | 7.32 | 15816358 | |
| MESH:D008107 | Liver Diseases | Plant Extracts | 7.32 | 17034775 | |
| MESH:D017114 | Liver Failure, Acute | Acetaminophen | 2.59 | 17185352 16871587 | |
| MESH:D008113 | Liver Neoplasms | 2,6-dinitrotoluene | 26.66 | 7678174 | |
| MESH:D008113 | Liver Neoplasms | 2-Acetylaminofluorene | 26.66 | 10672840 10737359 11376686 14678523 16273603 18001218 | |
| MESH:D008113 | Liver Neoplasms | Arsenic | 26.66 | 16368122 | |
| MESH:D008113 | Liver Neoplasms | Benzo(a)pyrene | 26.66 | 21137059 20195826 | |
| MESH:D008113 | Liver Neoplasms | Fluorouracil | 26.66 | 15113037 18383874 16603448 17045692 | |
| MESH:D008113 | Liver Neoplasms | pirinixic acid | 26.66 | 20007298 15890375 16377806 | |
| MESH:D008113 | Liver Neoplasms | Plant Extracts | 26.66 | 19168119 | |
| MESH:D008113 | Liver Neoplasms | sodium arsenite | 26.66 | 15276417 16712894 | |
| MESH:D008113 | Liver Neoplasms | Tamoxifen | 26.66 | 16684651 | |
| MESH:D008113 | Liver Neoplasms | Tetrachlorodibenzodioxin | 26.66 | 16984957 | |
| MESH:D008114 | Liver Neoplasms, Experimental | 2,6-dinitrotoluene | 16.91 | 2876784 6135515 2876786 | |
| MESH:D008114 | Liver Neoplasms, Experimental | 2-Acetylaminofluorene | 16.91 | 534488 1399818 6150874 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Deoxycholic Acid | 16.91 | 6150874 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Methylcholanthrene | 16.91 | 1399818 598648 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Polychlorinated Biphenyls | 16.91 | 1423854 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Tetrachlorodibenzodioxin | 16.91 | 12151625 | |
| MESH:D008171 | Lung Diseases | Hydrochloric Acid | 9.44 | 16784557 | |
| MESH:D008171 | Lung Diseases | Ozone | 9.44 | 19066396 8266340 | |
| MESH:D008171 | Lung Diseases | sodium arsenite | 9.44 | 19095001 | |
| MESH:D017563 | Lung Diseases, Interstitial | Valproic Acid | 3.52 | 17228818 | |
| MESH:D055370 | Lung Injury | Asbestos, Crocidolite | 11.24 | 17365036 | |
| MESH:D055370 | Lung Injury | Hydrochloric Acid | 11.24 | 20597076 15044056 21114838 18573544 17627322 18339021 18497604 16129981 15090967 15607125 19262391 21311175 19644408 11395602 | |
| MESH:D055370 | Lung Injury | Ozone | 11.24 | 20417186 | |
| MESH:D008175 | Lung Neoplasms | 2-Acetylaminofluorene | 19.39 | 11376686 | |
| MESH:D008175 | Lung Neoplasms | Arsenic | 19.39 | 17306315 17976673 19168569 | |
| MESH:D008175 | Lung Neoplasms | Benzo(a)pyrene | 19.39 | 20464547 20135361 18569708 18520028 18816296 6695378 20064080 17053015 20869020 | |
| MESH:D008175 | Lung Neoplasms | Dexamethasone | 19.39 | 15824018 11195469 | |
| MESH:D008175 | Lung Neoplasms | Fluorouracil | 19.39 | 15246190 | |
| MESH:D008175 | Lung Neoplasms | Isotretinoin | 19.39 | 15899809 | |
| MESH:D008175 | Lung Neoplasms | Methylcholanthrene | 19.39 | 10545420 16271038 11893704 20970405 7750092 1399818 17909032 21163286 20512841 16337739 15390079 6695378 9230183 | |
| MESH:D008175 | Lung Neoplasms | Ozone | 19.39 | 7614698 8597069 | |
| MESH:D008175 | Lung Neoplasms | Plant Extracts | 19.39 | 20869020 | |
| MESH:D008175 | Lung Neoplasms | sodium arsenite | 19.39 | 17077188 19931552 17306315 16712894 15276417 | |
| MESH:D008175 | Lung Neoplasms | Tamoxifen | 19.39 | 18625569 | |
| MESH:D008175 | Lung Neoplasms | Tetrachlorodibenzodioxin | 19.39 | 19555203 11884234 | |
| MESH:D008178 | Lupus Erythematosus, Cutaneous | Fluorouracil | 4.06 | 15086387 | |
| MESH:D008223 | Lymphoma | decitabine | 6.06 | 19470736 | |
| MESH:D008223 | Lymphoma | Etoposide | 6.06 | 12854902 12556972 | |
| MESH:D015674 | Mammary Neoplasms, Animal | Tamoxifen | 3.03 | 19428831 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | Estradiol | 13.44 | 17203775 11807958 11408345 16891317 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | gefitinib | 13.44 | 18375820 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | Genistein | 13.44 | 12929590 14578162 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | Progesterone | 13.44 | 17203775 11408345 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | Tamoxifen | 13.44 | 19196722 11731420 19196723 14580682 16827153 | |
| MESH:D020149 | Manganese Poisoning | Estradiol | 10.17 | 19453300 | |
| MESH:D020149 | Manganese Poisoning | Tamoxifen | 10.17 | 19453300 | |
| MESH:D008527 | Medulloblastoma | Tretinoin | 2.44 | 17453147 | |
| MESH:D008545 | Melanoma | decitabine | 9.95 | 17785578 16505122 | |
| MESH:D008545 | Melanoma | Isotretinoin | 9.95 | 17237267 | |
| MESH:D008545 | Melanoma | sodium arsenite | 9.95 | 19082730 16487513 | |
| MESH:D008545 | Melanoma | Tamoxifen | 9.95 | 19393235 12393984 | |
| MESH:D008545 | Melanoma | Tretinoin | 9.95 | 16752155 | |
| MESH:D008545 | Melanoma | Vitamin K 3 | 9.95 | 19082730 | |
| MESH:D018328 | Melanoma, Amelanotic | Tamoxifen | 3.45 | 15990972 | |
| MESH:D008546 | Melanoma, Experimental | Acetaminophen | 2.85 | 19513568 | |
| MESH:D008591 | Meningomyelocele | Tretinoin | 3.71 | 16940565 | |
| MESH:D008654 | Mesothelioma | Asbestos, Crocidolite | 2.83 | 16966607 18303189 16166281 | |
| MESH:D008679 | Metaplasia | Ozone | 4.36 | 10496685 | |
| MESH:D008881 | Migraine Disorders | Valproic Acid | 2.65 | 18765137 18803445 | |
| MESH:D020326 | Migraine without Aura | Dinoprostone | 4.56 | 11304026 | |
| MESH:D018200 | Mixed Tumor, Mullerian | Raloxifene | 4.81 | 15863610 | |
| MESH:D009062 | Mouth Neoplasms | Benzo(a)pyrene | 6.58 | 16381670 | |
| MESH:D009062 | Mouth Neoplasms | Fluorouracil | 6.58 | 16757204 18986760 | |
| MESH:D052016 | Mucositis | irinotecan | 4.28 | 17159606 | |
| MESH:D009101 | Multiple Myeloma | decitabine | 9.03 | 18172295 | |
| MESH:D009101 | Multiple Myeloma | Dexamethasone | 9.03 | 16118317 15867202 15744524 | |
| MESH:D009101 | Multiple Myeloma | Raloxifene | 9.03 | 16497877 | |
| MESH:D009135 | Muscular Diseases | pirinixic acid | 2.79 | 16239165 | |
| MESH:D009139 | Musculoskeletal Abnormalities | Valproic Acid | 3.36 | 8888407 | |
| MESH:D009190 | Myelodysplastic Syndromes | decitabine | 13.71 | 19157545 18608210 19010910 16882708 | |
| MESH:D009190 | Myelodysplastic Syndromes | Dexamethasone | 13.71 | 9809623 | |
| MESH:D009190 | Myelodysplastic Syndromes | Tretinoin | 13.71 | 17596541 | |
| MESH:D009190 | Myelodysplastic Syndromes | Valproic Acid | 13.71 | 17596541 | |
| MESH:D009203 | Myocardial Infarction | Genistein | 7.43 | 17141266 | |
| MESH:D009203 | Myocardial Infarction | Hydrochloric Acid | 7.43 | 18534312 | |
| MESH:D009203 | Myocardial Infarction | pirinixic acid | 7.43 | 19151258 | |
| MESH:D017202 | Myocardial Ischemia | Arsenic | 7.00 | 15371236 | |
| MESH:D017202 | Myocardial Ischemia | Tetrachlorodibenzodioxin | 7.00 | 12213967 | |
| MESH:D015428 | Myocardial Reperfusion Injury | Estradiol | 10.79 | 16810080 | |
| MESH:D015428 | Myocardial Reperfusion Injury | Genistein | 10.79 | 17141266 | |
| MESH:D015428 | Myocardial Reperfusion Injury | pirinixic acid | 10.79 | 16411023 | |
| MESH:D009232 | Myxoma | Raloxifene | 4.81 | 16343187 | |
| MESH:D009336 | Necrosis | 2,6-dinitrotoluene | 3.13 | 7678174 18551238 | |
| MESH:D009362 | Neoplasm Metastasis | irinotecan | 4.75 | 18259882 | |
| MESH:D009362 | Neoplasm Metastasis | Tamoxifen | 4.75 | 19393235 | |
| MESH:D009364 | Neoplasm Recurrence, Local | Tamoxifen | 2.22 | 19410462 | |
| MESH:D009369 | Neoplasms | Benzo(a)pyrene | 14.30 | 11141357 | |
| MESH:D009369 | Neoplasms | decitabine | 14.30 | 17925555 19116145 19470736 | |
| MESH:D009369 | Neoplasms | Fluorouracil | 14.30 | 18600527 16928823 18239605 | |
| MESH:D009369 | Neoplasms | pirinixic acid | 14.30 | 17405874 | |
| MESH:D009369 | Neoplasms | sodium arsenite | 14.30 | 11559025 | |
| MESH:D009369 | Neoplasms | Tretinoin | 14.30 | 16946489 16594593 | |
| MESH:D009374 | Neoplasms, Experimental | sodium arsenite | 2.96 | 20056578 | |
| MESH:D009376 | Neoplasms, Hormone-Dependent | Tamoxifen | 3.26 | 19200415 19196722 19189210 | |
| MESH:D009389 | Neovascularization, Pathologic | Estradiol | 3.01 | 17289903 | |
| MESH:D009421 | Nervous System Malformations | bisphenol A | 23.40 | 16427766 11399458 | |
| MESH:D009421 | Nervous System Malformations | Estradiol | 23.40 | 11399458 16427766 | |
| MESH:D009421 | Nervous System Malformations | Genistein | 23.40 | 16427766 | |
| MESH:D009421 | Nervous System Malformations | Tetrachlorodibenzodioxin | 23.40 | 14600291 | |
| MESH:D009421 | Nervous System Malformations | Tretinoin | 23.40 | 9125849 | |
| MESH:D009436 | Neural Tube Defects | Arsenic | 13.09 | 16620997 | |
| MESH:D009436 | Neural Tube Defects | sodium arsenite | 13.09 | 12854658 | |
| MESH:D009436 | Neural Tube Defects | Tretinoin | 13.09 | 9142499 | |
| MESH:D009436 | Neural Tube Defects | Valproic Acid | 13.09 | 16359493 8888407 | |
| MESH:D019954 | Neurobehavioral Manifestations | Plant Extracts | 4.47 | 17168769 | |
| MESH:D009447 | Neuroblastoma | irinotecan | 5.99 | 8761367 | |
| MESH:D009447 | Neuroblastoma | Isotretinoin | 5.99 | 17368321 | |
| MESH:D019636 | Neurodegenerative Diseases | Acetaminophen | 2.26 | 18514411 | |
| MESH:D017599 | Neuroectodermal Tumors | irinotecan | 4.00 | 8761367 | |
| MESH:D020078 | Neurogenic Inflammation | Arsenic | 3.69 | 17056641 | |
| MESH:D020258 | Neurotoxicity Syndromes | Fluorouracil | 2.91 | 16436463 | |
| MESH:D009765 | Obesity | pirinixic acid | 3.92 | 20558911 | |
| MESH:D009765 | Obesity | Plant Extracts | 3.92 | 19056576 20132043 | |
| MESH:D009784 | Occupational Diseases | 2,6-dinitrotoluene | 7.24 | 16049721 | |
| MESH:D009784 | Occupational Diseases | Hydrochloric Acid | 7.24 | 12378975 | |
| MESH:D010005 | Osteoarthropathy, Secondary Hypertrophic | Dinoprostone | 5.73 | 18500342 | |
| MESH:D010024 | Osteoporosis | Genistein | 5.68 | 19401787 | |
| MESH:D010024 | Osteoporosis | Raloxifene | 5.68 | 17882678 19059307 15775268 | |
| MESH:D015663 | Osteoporosis, Postmenopausal | Genistein | 7.88 | 16169203 | |
| MESH:D015663 | Osteoporosis, Postmenopausal | Raloxifene | 7.88 | 15579764 15758505 17893378 17823083 | |
| MESH:D010049 | Ovarian Diseases | bisphenol A | 4.25 | 11985600 | |
| MESH:D010051 | Ovarian Neoplasms | therapeutic | 15313392 | ||
| MESH:D010051 | Ovarian Neoplasms | Arsenic | 21.76 | 17306315 | |
| MESH:D010051 | Ovarian Neoplasms | decitabine | 21.76 | 19259094 19331143 | |
| MESH:D010051 | Ovarian Neoplasms | Estradiol | 21.76 | 19401270 | |
| MESH:D010051 | Ovarian Neoplasms | Genistein | 21.76 | 19005980 | |
| MESH:D010051 | Ovarian Neoplasms | Progesterone | 21.76 | 17393432 16525653 | |
| MESH:D010051 | Ovarian Neoplasms | sodium arsenite | 21.76 | 17306315 15276417 | |
| MESH:D010051 | Ovarian Neoplasms | Tretinoin | 21.76 | 16936753 | |
| MESH:D010051 | Ovarian Neoplasms | U 0126 | 21.76 | 16211241 | |
| MESH:D010146 | Pain | Acetaminophen | 4.61 | 16870215 | |
| MESH:D010146 | Pain | Tretinoin | 4.61 | 16870215 | |
| MESH:D010190 | Pancreatic Neoplasms | decitabine | 9.61 | 19294695 | |
| MESH:D010190 | Pancreatic Neoplasms | Etoposide | 9.61 | 19003803 | |
| MESH:D010190 | Pancreatic Neoplasms | Fluorouracil | 9.61 | 16500647 16929163 19003803 15113037 | |
| MESH:D010190 | Pancreatic Neoplasms | Tretinoin | 9.61 | 15976015 | |
| MESH:D010212 | Papilloma | Hydrogen Peroxide | 7.33 | 12065085 | |
| MESH:D010212 | Papilloma | Plant Extracts | 7.33 | 16517061 15173996 | |
| MESH:D010300 | Parkinson Disease | Polychlorinated Biphenyls | 3.08 | 16702228 | |
| MESH:D010382 | Peliosis Hepatis | Tetrachlorodibenzodioxin | 3.50 | 12520081 | |
| MESH:D010523 | Peripheral Nervous System Diseases | Arsenic | 3.48 | 16093927 | |
| MESH:D016491 | Peripheral Vascular Diseases | Arsenic | 4.26 | 16905509 6392382 15371236 | |
| MESH:D010538 | Peritonitis | Ozone | 3.42 | 16369182 | |
| MESH:D010995 | Pleural Diseases | Asbestos, Crocidolite | 4.18 | 10923243 | |
| MESH:D011014 | Pneumonia | Ozone | 3.66 | 18381685 18929643 18007984 | |
| MESH:D011015 | Pneumonia, Aspiration | Hydrochloric Acid | 4.64 | 18573544 18497604 15970105 15607125 | |
| MESH:D017119 | Porphyria Cutanea Tarda | Tetrachlorodibenzodioxin | 2.86 | 18163543 | |
| MESH:D054198 | Precursor Cell Lymphoblastic Leukemia-Lymphoma | Dexamethasone | 3.09 | 21297632 | |
| MESH:D011297 | Prenatal Exposure Delayed Effects | bisphenol A | 17.33 | 10548101 | |
| MESH:D011297 | Prenatal Exposure Delayed Effects | Isotretinoin | 17.33 | 18769834 | |
| MESH:D011297 | Prenatal Exposure Delayed Effects | Tetrachlorodibenzodioxin | 17.33 | 11118676 11399792 11896295 11222880 | |
| MESH:D011297 | Prenatal Exposure Delayed Effects | Valproic Acid | 17.33 | 20603192 | |
| MESH:D055728 | Primary Myelofibrosis | decitabine | 4.01 | 17616702 | |
| MESH:D011470 | Prostatic Hyperplasia | Calcitriol | 4.05 | 15572423 | |
| MESH:D019048 | Prostatic Intraepithelial Neoplasia | bisphenol A | 8.34 | 20887781 | |
| MESH:D019048 | Prostatic Intraepithelial Neoplasia | Estradiol | 8.34 | 20887781 | |
| MESH:D011471 | Prostatic Neoplasms | Arsenic | 5.82 | 16140617 | |
| MESH:D011471 | Prostatic Neoplasms | Benzo(a)pyrene | 5.82 | 17292933 | |
| MESH:D011471 | Prostatic Neoplasms | bisphenol A | 5.82 | 16740699 | |
| MESH:D011471 | Prostatic Neoplasms | Calcitriol | 5.82 | 18247401 16644109 15754350 12479363 16289102 | |
| MESH:D011471 | Prostatic Neoplasms | Estradiol | 5.82 | 16740699 | |
| MESH:D011471 | Prostatic Neoplasms | Etoposide | 5.82 | 17172428 | |
| MESH:D011471 | Prostatic Neoplasms | Fluorouracil | 5.82 | 18626508 19082440 | |
| MESH:D011471 | Prostatic Neoplasms | gefitinib | 5.82 | 17914592 15651060 16685379 | |
| MESH:D011471 | Prostatic Neoplasms | Genistein | 5.82 | 16925846 15378649 15256057 | |
| MESH:D011471 | Prostatic Neoplasms | Plant Extracts | 5.82 | 17804756 14666653 | |
| MESH:D011471 | Prostatic Neoplasms | Polychlorinated Biphenyls | 5.82 | 15721890 | |
| MESH:D011471 | Prostatic Neoplasms | Raloxifene | 5.82 | 15731164 16536755 16220300 | |
| MESH:D011471 | Prostatic Neoplasms | sodium arsenite | 5.82 | 16039940 | |
| MESH:D011471 | Prostatic Neoplasms | Tamoxifen | 5.82 | 15067354 | |
| MESH:D011507 | Proteinuria | Arsenic | 7.03 | 21343184 | |
| MESH:D011507 | Proteinuria | Tretinoin | 7.03 | 16636307 | |
| MESH:D019310 | Pseudolymphoma | Valproic Acid | 3.79 | 11422049 12752131 | |
| MESH:D011596 | Psychomotor Disorders | Isotretinoin | 5.18 | 18769834 | |
| MESH:D011625 | Pterygium | Tretinoin | 4.06 | 16723453 | |
| MESH:D011629 | Puberty, Precocious | bisphenol A | 4.05 | 10548101 | |
| MESH:D001261 | Pulmonary Atelectasis | Hydrochloric Acid | 5.27 | 20597076 | |
| MESH:D011654 | Pulmonary Edema | Hydrochloric Acid | 4.47 | 15090967 | |
| MESH:D011658 | Pulmonary Fibrosis | Asbestos, Crocidolite | 5.14 | 17365031 15814490 17322281 17975199 | |
| MESH:D011658 | Pulmonary Fibrosis | gefitinib | 5.14 | 18424623 | |
| MESH:D011693 | Purpura | Raloxifene | 4.81 | 15770314 | |
| MESH:D012004 | Rectal Neoplasms | Fluorouracil | 3.38 | 18722050 18286688 16160472 15538739 | |
| MESH:D015427 | Reperfusion Injury | pirinixic acid | 1.98 | 19058328 | |
| MESH:D012128 | Respiratory Distress Syndrome, Adult | Dexamethasone | 7.33 | 18379247 11700416 | |
| MESH:D012128 | Respiratory Distress Syndrome, Adult | Hydrochloric Acid | 7.33 | 16784557 18339021 16129981 18549715 17627322 | |
| MESH:D012133 | Respiratory Paralysis | Hydrochloric Acid | 5.61 | 11510729 | |
| MESH:D015619 | Respiratory System Abnormalities | Tetrachlorodibenzodioxin | 3.14 | 18990726 | |
| MESH:D012140 | Respiratory Tract Diseases | Hydrochloric Acid | 4.42 | 20516732 | |
| MESH:D012208 | Rhabdomyosarcoma | decitabine | 14.59 | 19155313 | |
| MESH:D012208 | Rhabdomyosarcoma | Tretinoin | 14.59 | 16283617 16116481 | |
| MESH:D012208 | Rhabdomyosarcoma | Valproic Acid | 14.59 | 19155313 | |
| MESH:D012468 | Salivary Gland Neoplasms | Progesterone | 2.54 | 18045962 | |
| MESH:D012512 | Sarcoma, Ewing's | Etoposide | 4.01 | 14601052 | |
| MESH:D012559 | Schizophrenia | Valproic Acid | 1.95 | 19110320 15737665 | |
| MESH:D012640 | Seizures | 2,6-dinitrotoluene | 4.21 | 18551238 | |
| MESH:D012640 | Seizures | Valproic Acid | 4.21 | 11044598 14763951 11738929 16876388 3137016 15475178 1511512 17978042 | |
| MESH:D012852 | Sinusitis | Phenylephrine | 3.97 | 7327846 | |
| MESH:D012871 | Skin Diseases | Arsenic | 2.51 | 16353154 18709164 16702368 17548696 6392382 17938729 19834688 17453740 16759981 17050553 15952646 | |
| MESH:D012878 | Skin Neoplasms | Arsenic | 24.87 | 17029826 19538983 15504454 17976673 17050553 16251483 | |
| MESH:D012878 | Skin Neoplasms | Benzo(a)pyrene | 24.87 | 19755658 10029692 | |
| MESH:D012878 | Skin Neoplasms | Hydrogen Peroxide | 24.87 | 12065085 | |
| MESH:D012878 | Skin Neoplasms | Plant Extracts | 24.87 | 16517061 15173996 | |
| MESH:D012878 | Skin Neoplasms | sodium arsenite | 24.87 | 19524636 18572023 | |
| MESH:D012878 | Skin Neoplasms | tert-Butylhydroperoxide | 24.87 | 8532709 | |
| MESH:D012878 | Skin Neoplasms | Tetrachlorodibenzodioxin | 24.87 | 16192470 | |
| MESH:D012878 | Skin Neoplasms | Tretinoin | 24.87 | 16467112 | |
| MESH:D013088 | Spermatocele | Tamoxifen | 3.55 | 16709447 | |
| MESH:D013119 | Spinal Cord Injuries | Progesterone | 8.44 | 15862959 16503802 | |
| MESH:D013119 | Spinal Cord Injuries | Tamoxifen | 8.44 | 19457130 | |
| MESH:D016135 | Spinal Dysraphism | sodium arsenite | 7.59 | 12854658 | |
| MESH:D016135 | Spinal Dysraphism | Valproic Acid | 7.59 | 19490988 | |
| MESH:D013226 | Status Epilepticus | Valproic Acid | 3.79 | 12833885 | |
| MESH:D013272 | Stomach Diseases | Dexamethasone | 8.46 | 15472012 | |
| MESH:D013272 | Stomach Diseases | Rolipram | 8.46 | 15038085 | |
| MESH:D013274 | Stomach Neoplasms | marker/mechanism|therapeutic | 15723263 15940630 16367923 | ||
| MESH:D013274 | Stomach Neoplasms | Benzo(a)pyrene | 10.46 | 2093021 20155912 | |
| MESH:D013274 | Stomach Neoplasms | decitabine | 10.46 | 19037991 | |
| MESH:D013274 | Stomach Neoplasms | Fluorouracil | 10.46 | 16424979 17522103 19015929 17172411 18396642 17498489 18567086 19084572 16951190 15786421 | |
| MESH:D013274 | Stomach Neoplasms | irinotecan | 10.46 | 15723263 | |
| MESH:D013274 | Stomach Neoplasms | loxtidine | 10.46 | 15940630 | |
| MESH:D013274 | Stomach Neoplasms | nitrosobenzylmethylamine | 10.46 | 17575124 12958204 | |
| MESH:D013274 | Stomach Neoplasms | Tretinoin | 10.46 | 17261132 | |
| MESH:D013274 | Stomach Neoplasms | YF 476 | 10.46 | 15940630 | |
| MESH:D013276 | Stomach Ulcer | Dexamethasone | 12.01 | 15138204 | |
| MESH:D013276 | Stomach Ulcer | Hydrochloric Acid | 12.01 | 17189318 16755016 15309881 | |
| MESH:D013276 | Stomach Ulcer | Plant Extracts | 12.01 | 18193104 17135157 18237397 15255614 12787963 | |
| MESH:D013276 | Stomach Ulcer | Rolipram | 12.01 | 14567935 | |
| MESH:D020521 | Stroke | Raloxifene | 3.23 | 16837676 | |
| MESH:D019966 | Substance-Related Disorders | bisphenol A | 3.26 | 16045194 16684133 | |
| MESH:D013705 | Temporomandibular Joint Disorders | Plant Extracts | 4.73 | 17997062 | |
| MESH:D013959 | Thyroid Diseases | Tetrachlorodibenzodioxin | 3.16 | 12697716 | |
| MESH:D013964 | Thyroid Neoplasms | 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine | 12.54 | 16940797 | |
| MESH:D013964 | Thyroid Neoplasms | decitabine | 12.54 | 17967635 | |
| MESH:D013964 | Thyroid Neoplasms | gefitinib | 12.54 | 16940797 | |
| MESH:D013964 | Thyroid Neoplasms | Tretinoin | 12.54 | 16026305 17045167 | |
| MESH:D013978 | Tibial Fractures | Estradiol | 11.23 | 19048282 | |
| MESH:D013978 | Tibial Fractures | Raloxifene | 11.23 | 19048282 | |
| MESH:D014062 | Tongue Neoplasms | Fluorouracil | 7.68 | 16280240 | |
| MESH:D014062 | Tongue Neoplasms | Tretinoin | 7.68 | 16051514 | |
| MESH:D014178 | Translocation, Genetic | Valproic Acid | 4.48 | 17262798 | |
| MESH:D014376 | Tuberculosis | Tretinoin | 2.73 | 16040207 | |
| MESH:D020194 | Unverricht-Lundborg Syndrome | Valproic Acid | 3.79 | 3119515 | |
| MESH:D001749 | Urinary Bladder Neoplasms | 2,6-dinitrotoluene | 22.21 | 16049721 | |
| MESH:D001749 | Urinary Bladder Neoplasms | 2-Acetylaminofluorene | 22.21 | 15289314 1399818 15867355 | |
| MESH:D001749 | Urinary Bladder Neoplasms | Arsenic | 22.21 | 17306315 18640142 11144890 19429237 19322015 15987713 17976673 | |
| MESH:D001749 | Urinary Bladder Neoplasms | Benzo(a)pyrene | 22.21 | 17053015 | |
| MESH:D001749 | Urinary Bladder Neoplasms | decitabine | 22.21 | 17616700 19087683 | |
| MESH:D001749 | Urinary Bladder Neoplasms | Raloxifene | 22.21 | 17572228 | |
| MESH:D001749 | Urinary Bladder Neoplasms | sodium arsenite | 22.21 | 16712894 17306315 11723127 16452187 | |
| MESH:D001749 | Urinary Bladder Neoplasms | Tamoxifen | 22.21 | 8653321 16712894 17572228 | |
| MESH:D014564 | Urogenital Abnormalities | Valproic Acid | 3.92 | 8888407 | |
| MESH:D014571 | Urologic Neoplasms | 2,6-dinitrotoluene | 3.59 | 10091137 | |
| MESH:D014581 | Urticaria | Acetaminophen | 2.31 | 10982225 | |
| MESH:D002583 | Uterine Cervical Neoplasms | Fluorouracil | 12.13 | 16803524 | |
| MESH:D002583 | Uterine Cervical Neoplasms | sodium arsenite | 12.13 | 11813266 | |
| MESH:D002583 | Uterine Cervical Neoplasms | Tretinoin | 12.13 | 16129372 | |
| MESH:D014591 | Uterine Diseases | bisphenol A | 4.26 | 14652134 | |
| MESH:D014594 | Uterine Neoplasms | sulindac sulfide | 3.96 | 18645019 | |
| MESH:D014604 | Uveal Neoplasms | decitabine | 10.35 | 17785578 | |
| MESH:D014604 | Uveal Neoplasms | Tretinoin | 10.35 | 16752155 | |
| MESH:D014605 | Uveitis | Dexamethasone | 4.07 | 1336536 | |
| MESH:D014623 | Vaginal Diseases | cis-1R-(4'-pyrrolidinoethoxyphenyl)-2S-phenyl-6-hydroxy-1,2,3,4-tetrahydronaphthalene, tartrate salt | 6.96 | 16837883 | |
| MESH:D014652 | Vascular Diseases | Arsenic | 9.42 | 17056641 | |
| MESH:D014652 | Vascular Diseases | sodium arsenite | 9.42 | 17056641 | |
| MESH:D054079 | Vascular Malformations | Tetrachlorodibenzodioxin | 3.85 | 12125929 | |
| MESH:D054556 | Venous Thromboembolism | Raloxifene | 4.46 | 16837676 | |
| MESH:D018487 | Ventricular Dysfunction, Left | Plant Extracts | 4.03 | 18097624 | |
| MESH:D020257 | Ventricular Remodeling | Plant Extracts | 4.58 | 18097624 | |
| MESH:D014820 | Vitiligo | Tretinoin | 3.36 | 16761959 | |
| MESH:D014846 | Vulvar Neoplasms | Raloxifene | 4.81 | 16343187 | |
| MESH:D019282 | Wasting Syndrome | Tetrachlorodibenzodioxin | 3.50 | 15886252 | |
| MESH:D009396 | Wilms Tumor | Tretinoin | 3.33 | 16287080 | |
| MESH:D014947 | Wounds and Injuries | Estrogens | 7.17 | 11172683 | |
| MESH:D014947 | Wounds and Injuries | Plant Extracts | 7.17 | 20213670 19894650 |
| Pathway ID | Pathway Name |
|---|---|
| KEGG:04012 | ErbB signaling pathway |
Pharmacogenomics Knowledge Base