AutismKB 2.0

Annotation Detail for ZNF710


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:ZNF710 ( DKFZp547K1113,FLJ00306,FLJ37393,MGC163413 )
Gene Full Name: zinc finger protein 710
Band: 15q26.1
Quick LinksEntrez ID:374655; OMIM: NA; Uniprot ID:ZN710_HUMAN; ENSEMBL ID: ENSG00000140548; HGNC ID: 25352
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000638 Amiodarone Amiodarone results in increased expression of ZNF710 mRNAincreases expression 19774075
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of ZNF710 mRNAdecreases expression 20064835
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of ZNF710 mRNAaffects binding|increases activity|increases expression 19710929
D019772 Topotecan ZNF710 protein affects the susceptibility to Topotecanaffects response to substance 16217747
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D055371 Acute Lung Injury pirinixic acid 3.5818653653
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 2.0620464547 20127859
MESH:D000236 Adenoma Benzo(a)pyrene 2.866695378
MESH:D018248 Adenoma, Liver Cell pirinixic acid 4.1116434500
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.6419183758
MESH:D001145 Arrhythmias, Cardiac Amiodarone 4.2018057881 18218290 20041841
MESH:D001281 Atrial Fibrillation Amiodarone 4.2019698954 18651412
MESH:D001778 Blood Coagulation Disorders Amiodarone 10.5319483382
MESH:D001778 Blood Coagulation Disorders pirinixic acid 10.5319483382
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 1.9920146248 17474063
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 2.1320419170
MESH:D002311 Cardiomyopathy, Dilated Amiodarone 3.0019225199 15710769
MESH:D002341 Carotid Artery Thrombosis Amiodarone 5.7218974383
MESH:D002779 Cholestasis pirinixic acid 3.1219176532
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.5718249437
MESH:D056486 Drug-Induced Liver Injury Amiodarone 2.4715265979 18218290
MESH:D004487 Edema pirinixic acid 2.9012083418
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 2.0816530937
MESH:D005234 Fatty Liver Amiodarone 9.2514986274
MESH:D005234 Fatty Liver pirinixic acid 9.2520131406 19236843
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 2.8320471113
MESH:D006333 Heart Failure pirinixic acid 2.7620558911
MESH:D006529 Hepatomegaly Amiodarone 10.5115265979
MESH:D006529 Hepatomegaly pirinixic acid 10.5116221962 19772884 19176532 18467677
MESH:D006937 Hypercholesterolemia Amiodarone 4.308137927 9751232
MESH:D006943 Hyperglycemia pirinixic acid 3.5820558911
MESH:D007037 Hypothyroidism Amiodarone 5.0817991464 18020914
MESH:D007333 Insulin Resistance pirinixic acid 2.8716306350
MESH:D008064 Lipidoses Amiodarone 3.7917567588 15342952
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 1.3515474484
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 4.7720195826 21137059
MESH:D008113 Liver Neoplasms pirinixic acid 4.7716377806 20007298 15890375
MESH:D008133 Long QT Syndrome Amiodarone 3.8911989578 15350150 17391786
MESH:D008171 Lung Diseases Amiodarone 3.6212587719
MESH:D017563 Lung Diseases, Interstitial Amiodarone 5.2018516814
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 1.5720464547 6695378 18816296 18569708 18520028 20135361 17053015 20869020 20064080
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.5016381670
MESH:D009135 Muscular Diseases pirinixic acid 4.0716239165
MESH:D009181 Mycoses Amiodarone 5.6212754197 17974566
MESH:D009203 Myocardial Infarction pirinixic acid 2.2719151258
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 3.2516411023
MESH:D009369 Neoplasms Benzo(a)pyrene 5.3911141357
MESH:D009369 Neoplasms pirinixic acid 5.3917405874
MESH:D009447 Neuroblastoma Topotecan 4.0215176712
MESH:D009765 Obesity pirinixic acid 1.8820558911
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.9117292933
MESH:D011658 Pulmonary Fibrosis Amiodarone 2.9711597910 12832656 12490602
MESH:D015427 Reperfusion Injury pirinixic acid 2.5519058328
OMIM:609620 SHORT QT SYNDROME 1 Amiodarone 5.7218724381
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 2.5219755658 10029692
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 1.5620155912 2093021
MESH:D013276 Stomach Ulcer Amiodarone 3.7418087811
MESH:D013610 Tachycardia Amiodarone 4.8011238279
MESH:D017180 Tachycardia, Ventricular Amiodarone 4.7019225199
MESH:D013959 Thyroid Diseases Amiodarone 5.4819731979
MESH:D013971 Thyrotoxicosis Amiodarone 5.4218020914 19584973
MESH:D016171 Torsades de Pointes Amiodarone 4.8217467628 11989578
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 2.3017053015
No data
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved