AutismKB 2.0

Annotation Detail for KCNG1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:KCNG1 ( K13,KCNG,KV6.1,MGC12878,kH2 )
Gene Full Name: potassium voltage-gated channel, subfamily G, member 1
Band: 20q13.13
Quick LinksEntrez ID:3755; OMIM: 603788; Uniprot ID:KCNG1_HUMAN; ENSEMBL ID: ENSG00000026559; HGNC ID: 6248
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C006632 arsenic trioxide arsenic trioxide results in increased expression of KCNG1 mRNAincreases expression 20458559
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of KCNG1 mRNAdecreases expression 20382639
D019259 Lamivudine [Zidovudine co-treated with Lamivudine] results in increased expression of KCNG1 mRNAaffects cotreatment|increases expression 15784690
D004958 Estradiol [Progesterone co-treated with Estradiol] results in increased expression of KCNG1 mRNAaffects cotreatment|increases expression 17404688
D011374 Progesterone [Progesterone co-treated with Estradiol] results in increased expression of KCNG1 mRNAaffects cotreatment|increases expression 17404688
D011374 Progesterone Progesterone results in increased expression of KCNG1 mRNAincreases expression 17404688
D015215 Zidovudine [Zidovudine co-treated with Lamivudine] results in increased expression of KCNG1 mRNAaffects cotreatment|increases expression 15784690
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000163 Acquired Immunodeficiency Syndrome Zidovudine 5.249612607
MESH:D000230 Adenocarcinoma arsenic trioxide 4.6119825857 11798837
MESH:D000230 Adenocarcinoma Estradiol 4.6111473722
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 4.0016206674
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 5.8617868700
MESH:D001930 Brain Injuries Progesterone 4.6815665606 15380490 15845082
MESH:D001943 Breast Neoplasms Estradiol 2.1819861407 12948864 18497071 17289903 14630087 16675129 17018787 17261762
MESH:D001943 Breast Neoplasms Progesterone 2.1817614352 15562024 16175315
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.6811589617
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.9316111702
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 3.1516217749 15073043 14691202 15553829 11135700
MESH:D006528 Carcinoma, Hepatocellular Estradiol 3.1516924424
MESH:D002291 Carcinoma, Papillary arsenic trioxide 5.4019014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.4212490120
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7.3520889678
MESH:D002471 Cell Transformation, Neoplastic Estradiol 7.3518566989
MESH:D015179 Colorectal Neoplasms arsenic trioxide 1.8620501625
MESH:D023903 Coronary Restenosis arsenic trioxide 4.5712609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 1.8910525206
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 4.4515213294
MESH:D003928 Diabetic Nephropathies Estradiol 3.7019279558
MESH:D003929 Diabetic Neuropathies Progesterone 4.9117187935
MESH:D004362 Drug Toxicity Lamivudine 9.5615040536
MESH:D004362 Drug Toxicity Zidovudine 9.5615040536
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 4.1617692515
MESH:D016889 Endometrial Neoplasms Estradiol 3.1711473722 18566989 19148513
MESH:D004715 Endometriosis Progesterone 4.0716134523
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 4.6820426865
MESH:D004938 Esophageal Neoplasms arsenic trioxide 4.6812903497
MESH:D005234 Fatty Liver arsenic trioxide 9.2415073043
MESH:D005234 Fatty Liver Zidovudine 9.2418299183
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.6416904648
MESH:D006402 Hematologic Diseases Zidovudine 5.0612579204
MESH:D006509 Hepatitis B Lamivudine 5.4317703166
MESH:D019694 Hepatitis B, Chronic Lamivudine 5.4315274664 16476009 12044531 15631357 15309715
MESH:D006558 Herpes Genitalis Estradiol 5.5515709030
MESH:D015658 HIV Infections Lamivudine 7.5411141242 17530837 20032539 9296927
MESH:D015658 HIV Infections Zidovudine 7.5420032539 17358032 11698656 11141242 11363243
MESH:D019584 Hot Flashes Estradiol 4.2717088409
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 4.8215869954
MESH:D007249 Inflammation Progesterone 2.7415869954
MESH:D007333 Insulin Resistance Estradiol 3.1616393666 16627594
MESH:D007674 Kidney Diseases Estradiol 2.7415618244
MESH:D007680 Kidney Neoplasms Estradiol 8.5615610895
MESH:D007680 Kidney Neoplasms Zidovudine 8.5612579204
MESH:D007938 Leukemia arsenic trioxide 2.9615070760
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 10.9512560223 17077332
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Zidovudine 10.9520370541
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.7716972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.6614633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 4.0919077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.1816467208 17050201 16968895 19850784 20471514
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 3.4112712474 15748426 19642359 12679006 17712046 16330433 17107899 16331271 19035177 12018890 11468182 17217047 16112521 15336539 16823087 17869043 19075265 19225113 9834237 16966277 15213294 15622746 16891316 11161223 17649720
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.7316882451
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 1.6814716833 14659978
MESH:D008113 Liver Neoplasms arsenic trioxide 2.4314682389
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 2.9120377131
MESH:D008133 Long QT Syndrome arsenic trioxide 3.5915213294
MESH:D008175 Lung Neoplasms arsenic trioxide 2.8219825857 11798837
MESH:D008175 Lung Neoplasms Zidovudine 2.8218800350
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 6.6917203775 11807958 16891317 11408345
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 6.6917203775 11408345
MESH:D020149 Manganese Poisoning Estradiol 5.0019453300
MESH:D048629 Micronuclei, Chromosome-Defective Zidovudine 6.3617358032
MESH:D009101 Multiple Myeloma arsenic trioxide 3.3215949261 19549372 19417148 14977855 11468182
MESH:D009182 Mycosis Fungoides arsenic trioxide 5.1918349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 3.3016882451 16105982
MESH:D015428 Myocardial Reperfusion Injury Estradiol 3.5216810080
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 4.3416624393
MESH:D009389 Neovascularization, Pathologic Estradiol 4.1917289903
MESH:D009421 Nervous System Malformations Estradiol 4.0311399458 16427766
MESH:D009436 Neural Tube Defects arsenic trioxide 3.3110525206
MESH:D010051 Ovarian Neoplasms arsenic trioxide 8.3716624393 19769630 12452020
MESH:D010051 Ovarian Neoplasms Estradiol 8.3719401270
MESH:D010051 Ovarian Neoplasms Progesterone 8.3716525653 17393432
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 2.6115580305
MESH:D010235 Paraganglioma arsenic trioxide 4.5119927285
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 4.2120887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 3.1519131511
MESH:D011471 Prostatic Neoplasms Estradiol 3.1516740699
MESH:D012206 Rhabdomyolysis Lamivudine 6.009296927
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.9418045962
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 4.3416646077
MESH:D013119 Spinal Cord Injuries Progesterone 4.7416503802 15862959
MESH:D013274 Stomach Neoplasms arsenic trioxide 2.7717007042
MESH:D013274 Stomach Neoplasms Zidovudine 2.7717696246
MESH:D013964 Thyroid Neoplasms arsenic trioxide 3.3219014326
MESH:D013978 Tibial Fractures Estradiol 5.2119048282
MESH:D016171 Torsades de Pointes arsenic trioxide 4.4215213294
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 2.5812973940 20435036 11780464 12845720
MESH:D014625 Vaginal Neoplasms Zidovudine 5.1812579204
No data
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved