AutismKB 2.0

Annotation Detail for SLC26A5


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Basic Information Top
Gene Symbol:SLC26A5 ( DFNB61,MGC118886,MGC118887,MGC118888,MGC118889,PRES )
Gene Full Name: solute carrier family 26, member 5 (prestin)
Band: 7q22.1
Quick LinksEntrez ID:375611; OMIM: 604943; Uniprot ID:S26A5_HUMAN; ENSEMBL ID: ENSG00000170615; HGNC ID: 9359
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
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Desease Name
Deafness, autosomal recessive 61
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000643 Ammonium Chloride Ammonium Chloride affects the expression of SLC26A5 mRNAaffects expression 16483693
D005419 Flavonoids Flavonoids results in decreased expression of SLC26A5 mRNAdecreases expression 18035473
C025299 polyphenols polyphenols results in decreased expression of SLC26A5 mRNAdecreases expression 16293270
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 4.3018287403
MESH:D003110 Colonic Neoplasms polyphenols 2.7316293270
MESH:D056486 Drug-Induced Liver Injury polyphenols 2.8319370779
MESH:D006319 Hearing Loss, Sensorineural marker/mechanism
MESH:D007249 Inflammation Flavonoids 6.1017296493
MESH:D007249 Inflammation polyphenols 6.1016366677
MESH:D008107 Liver Diseases polyphenols 2.8616698588
MESH:D013705 Temporomandibular Joint Disorders polyphenols 6.1217997062
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Pharmacogenomics Knowledge Base Top
Drug Bank Top
Drugbank ID Action Drug Name Description
DB03122 - B-Octylglucoside Detergents
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018