AutismKB 2.0

Annotation Detail for PTAR1


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Basic Information Top
Gene Symbol:PTAR1 ( FLJ45604 )
Gene Full Name: protein prenyltransferase alpha subunit repeat containing 1
Band: 9q21.12
Quick LinksEntrez ID:375743; OMIM: NA; Uniprot ID:PTAR1_HUMAN; ENSEMBL ID: ENSG00000188647; HGNC ID: 30449
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of PTAR1 mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of PTAR1 mRNAaffects expression 17562736
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000799 Angioedema Acetaminophen 4.9110982225
MESH:D001321 Autistic Disorder Acetaminophen 1.3918445737
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 2.9916705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 2.993084413
MESH:D002386 Cataract Acetaminophen 2.8310977129
MESH:D003490 Cyanosis 2,4-dinitrotoluene 4.7818551238
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 4.0818551238 21346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 4.0811743745 11461765 2444490 18071297 19923254 14725611 18713872 12540782 16485898 17522070 17562736 12705907 19420014 14550746 10774834 19416960 16109766 14986274 16081117 10915739 10663392 16227642 15619225 11834606 19164858 16781746 19085960 11421492 19370779 19739265 16177239 11529661 15968718 11287661 12153990 17906064 11739529 12958197 16393943 12392966 12594235
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 5.1719426721
MESH:D005756 Gastritis Acetaminophen 4.7416983495
MESH:D006930 Hyperalgesia Acetaminophen 3.1116870215
MESH:D007674 Kidney Diseases Acetaminophen 2.4415629191 12587719
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 3.4116705839
MESH:D008107 Liver Diseases Acetaminophen 1.7116610002 12969438 11587558 19014921 12587719 19460945 16611625 19784758
MESH:D017114 Liver Failure, Acute Acetaminophen 3.7416871587 17185352
MESH:D008546 Melanoma, Experimental Acetaminophen 4.3319513568
MESH:D009336 Necrosis 2,4-dinitrotoluene 4.7418551238
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.3118514411
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 3.9312819281 16049721
MESH:D010146 Pain Acetaminophen 2.8216870215
MESH:D012640 Seizures 2,4-dinitrotoluene 2.8518551238
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 2.4316049721
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 5.2010091137
MESH:D014581 Urticaria Acetaminophen 3.5810982225
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018