Annotation Detail for KCNN3
Basic Information
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| Gene Symbol: | KCNN3 ( KCa2.3,SK3,SKCA3,hSK3 ) |
|---|
| Gene Full Name: | potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3 |
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| Band: | 1q21.3 |
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| Quick Links | Entrez ID:3782; OMIM: 602983; Uniprot ID:KCNN3_HUMAN; ENSEMBL ID: ENSG00000143603; HGNC ID: 6292 |
|---|
| Relate to Another Database: |
SFARIGene;
denovo-db |
| Desease ID | Desease Name |
|---|
| 1909 | Migraine |
| 2198 | Psychotic disorder |
| Desease Name |
|---|
| Atrial Fibrillation |
| CARDIOVASCULAR |
| PSYCH |
| anorexia nervosa |
| schizophrenia |
| psychosis |
| Desease Name |
|---|
| Atrial fibrillation |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D000643 |
Ammonium Chloride |
Ammonium Chloride affects the expression of KCNN3 mRNA | affects expression | 16483693
|
| D001564 |
Benzo(a)pyrene |
Benzo(a)pyrene results in increased expression of KCNN3 mRNA | increases expression | 20127859
|
| D005419 |
Flavonoids |
Flavonoids results in decreased expression of KCNN3 mRNA | decreases expression | 18035473
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000138 |
Acidosis |
|
Ammonium Chloride |
4.30 | 18287403 |
| MESH:D000230 |
Adenocarcinoma |
|
Benzo(a)pyrene |
2.06 | 20127859 20464547 |
| MESH:D000236 |
Adenoma |
|
Benzo(a)pyrene |
2.88 | 6695378 |
| MESH:D017544 |
Aortic Aneurysm, Abdominal |
|
Benzo(a)pyrene |
4.73 | 19183758 |
| MESH:D001281 |
Atrial Fibrillation |
marker/mechanism |
|
| 20173747 |
| MESH:D001943 |
Breast Neoplasms |
|
Benzo(a)pyrene |
1.99 | 20146248 17474063 |
| MESH:D002294 |
Carcinoma, Squamous Cell |
|
Benzo(a)pyrene |
2.14 | 20419170 |
| MESH:D004938 |
Esophageal Neoplasms |
|
Benzo(a)pyrene |
2.09 | 16530937 |
| MESH:D006330 |
Heart Defects, Congenital |
|
Benzo(a)pyrene |
2.85 | 20471113 |
| MESH:D007249 |
Inflammation |
|
Flavonoids |
2.84 | 17296493 |
| MESH:D008113 |
Liver Neoplasms |
|
Benzo(a)pyrene |
2.17 | 20195826 21137059 |
| MESH:D008175 |
Lung Neoplasms |
|
Benzo(a)pyrene |
1.57 | 20135361 18816296 20064080 18569708 20869020 20464547 6695378 17053015 18520028 |
| MESH:D009062 |
Mouth Neoplasms |
|
Benzo(a)pyrene |
3.53 | 16381670 |
| MESH:D009369 |
Neoplasms |
|
Benzo(a)pyrene |
2.35 | 11141357 |
| MESH:D011471 |
Prostatic Neoplasms |
|
Benzo(a)pyrene |
2.90 | 17292933 |
| MESH:D012878 |
Skin Neoplasms |
|
Benzo(a)pyrene |
2.54 | 10029692 19755658 |
| MESH:D013274 |
Stomach Neoplasms |
|
Benzo(a)pyrene |
1.56 | 20155912 2093021 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
Benzo(a)pyrene |
2.31 | 17053015 |
PharmGKB Accession:PA30072
| Releated disease ID |
Related disease Name |
| PA443459 | Atrial Fibrillation |
| Drugbank ID |
Action |
Drug Name |
Description |
|---|
| DB01110 |
antagonist |
Miconazole |
Antifungal Agents |
Related Pathway Information