AutismKB 2.0

Annotation Detail for KCNS1


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Basic Information Top
Gene Symbol:KCNS1 ( KV9.1 )
Gene Full Name: potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1
Band: 20q13.12
Quick LinksEntrez ID:3787; OMIM: 602905; Uniprot ID:KCNS1_HUMAN; ENSEMBL ID: ENSG00000124134; HGNC ID: 6300
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000643 Ammonium Chloride Ammonium Chloride affects the expression of KCNS1 mRNAaffects expression 16483693
D005419 Flavonoids Flavonoids results in increased expression of KCNS1 mRNAincreases expression 18035473
D009151 Mustard Gas Mustard Gas results in increased expression of KCNS1 mRNAincreases expression 15674844
C025299 polyphenols polyphenols results in decreased expression of KCNS1 mRNAdecreases expression 16293270
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 4.1918287403
MESH:D001249 Asthma Mustard Gas 2.8010378619
MESH:D001768 Blister Mustard Gas 5.7919167455
MESH:D001989 Bronchiolitis Obliterans Mustard Gas 5.7915286001
MESH:D029481 Bronchitis, Chronic Mustard Gas 5.7017687719 10378619
MESH:D003110 Colonic Neoplasms polyphenols 2.7216293270
MESH:D056486 Drug-Induced Liver Injury polyphenols 2.8219370779
MESH:D004487 Edema Mustard Gas 3.7311402378 9260866 11428631 11428647
MESH:D004890 Erythema Mustard Gas 5.799357497
MESH:D007249 Inflammation Flavonoids 9.6017296493
MESH:D007249 Inflammation Mustard Gas 9.6016001271 8975870 11428647 17524151 11428631 11428620 9357497 9260866 11402378
MESH:D007249 Inflammation polyphenols 9.6016366677
MESH:D008107 Liver Diseases polyphenols 2.8516698588
MESH:D008171 Lung Diseases Mustard Gas 3.7018161513 18702808
MESH:D008175 Lung Neoplasms Mustard Gas 2.178781369 3148597
MESH:D009503 Neutropenia Mustard Gas 4.437688884 16761898
MESH:D011041 Poisoning Mustard Gas 4.2615727166
MESH:D011537 Pruritus Mustard Gas 4.7218058305
MESH:D011658 Pulmonary Fibrosis Mustard Gas 3.0517620002 17894541 17720292 17266442 10334151
MESH:D012871 Skin Diseases Mustard Gas 2.7916961503 12880345 15451306
MESH:D013705 Temporomandibular Joint Disorders polyphenols 5.9717997062
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018