AutismKB 2.0

Annotation Detail for KDR


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:KDR ( CD309,FLK1,VEGFR,VEGFR2 )
Gene Full Name: kinase insert domain receptor (a type III receptor tyrosine kinase)
Band: 4q12
Quick LinksEntrez ID:3791; OMIM: 191306; Uniprot ID:VGFR2_HUMAN; ENSEMBL ID: ENSG00000128052; HGNC ID: 6307
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04144Endocytosis
hsa04510Focal adhesion
hsa04060Cytokine-cytokine receptor interaction
hsa04370VEGF signaling pathway
Pathway IDPathway Name
Signaling by VEGF
Pathway IDPathway Name
200030HIF-2-alpha transcription factor network
200065Signaling events mediated by TCPTP
200071S1P1 pathway
200161Signaling events mediated by VEGFR1 and VEGFR2
200109Integrins in angiogenesis
200196Notch-mediated HES/HEY network
Pathway IDPathway Name
P00056VEGF signaling pathway
P00005Angiogenesis
Pathway IDPathway Name
500649VEGF binds to VEGFR leading to receptor dimerization
500648VEGF ligand-receptor interactions
500650Neurophilin interactions with VEGF and VEGFR
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1804Chronic obstructive airway disease
1901Endometriosis
1934Cancer
2074Asthma
2134Amyotrophic lateral sclerosis
2146Lupus erythematosus
2178Retinal disease
2219Mucocutaneous lymph node syndrome
2220Dermatitis
2236Cardiovascular disease
Desease Name
Asthma
IMMUNE
kawasaki disease
No data
Desease Name
Hemangioma, capillary infantile, susceptibility to
Hemangioma, capillary infantile, somatic
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C029790 2,2',3',4,4',5-hexachlorobiphenyl [2,4,4'-trichlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of KDR mRNAaffects cotreatment|increases expression 15808785
C070055 2,3',4,4',5-pentachlorobiphenyl [2,4,4'-trichlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of KDR mRNAaffects cotreatment|increases expression 15808785
C029498 2,3-bis(3'-hydroxybenzyl)butane-1,4-diol 2,3-bis(3'-hydroxybenzyl)butane-1,4-diol inhibits the reaction [Estradiol results in increased expression of KDR protein]decreases reaction|increases expression 17289903
C029497 2,3-bis(3'-hydroxybenzyl)butyrolactone 2,3-bis(3'-hydroxybenzyl)butyrolactone inhibits the reaction [Estradiol results in increased expression of KDR protein]decreases reaction|increases expression 17289903
C081766 2,4,4'-trichlorobiphenyl [2,4,4'-trichlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of KDR mRNAaffects cotreatment|increases expression 15808785
C014024 2,4,5,2',4',5'-hexachlorobiphenyl [2,4,4'-trichlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of KDR mRNAaffects cotreatment|increases expression 15808785
C009828 2,4,5,2',5'-pentachlorobiphenyl [2,4,4'-trichlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of KDR mRNAaffects cotreatment|increases expression 15808785
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of KDR mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of KDR mRNAaffects expression 21346803
C500344 2-methoxyestradiol-3,17-bis-O,O-sulfamate 2-methoxyestradiol-3,17-bis-O,O-sulfamate analog results in decreased expression of KDR proteindecreases expression 17426705
C500344 2-methoxyestradiol-3,17-bis-O,O-sulfamate 2-methoxyestradiol-3,17-bis-O,O-sulfamate results in decreased expression of KDR proteindecreases expression 17426705
C022960 2-oxindole 2-oxindole analog results in decreased activity of KDR proteindecreases activity 15728459
C028451 3,4,3',4'-tetrachlorobiphenyl [3,4,3',4'-tetrachlorobiphenyl co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl] results in increased expression of KDR mRNAaffects cotreatment|increases expression 15808785
C027309 3,4,5,3',4',5'-hexachlorobiphenyl [3,4,3',4'-tetrachlorobiphenyl co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl] results in increased expression of KDR mRNAaffects cotreatment|increases expression 15808785
C023035 3,4,5,3',4'-pentachlorobiphenyl [3,4,3',4'-tetrachlorobiphenyl co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl] results in increased expression of KDR mRNAaffects cotreatment|increases expression 15808785
C500067 3-((5-(6-((3-chlorophenyl)amino)pyrazinyl)-3-pyridinyl)amino)-1-propanol 3-((5-(6-((3-chlorophenyl)amino)pyrazinyl)-3-pyridinyl)amino)-1-propanol binds to and results in decreased activity of KDR proteinaffects binding|decreases activity 15771433
C477639 3-(5-methyl-2-(2-oxo-1,2-dihydroindol-3-ylidenemethyl)-1H-pyrrol-3-yl)propionic acid 3-(5-methyl-2-(2-oxo-1,2-dihydroindol-3-ylidenemethyl)-1H-pyrrol-3-yl)propionic acid results in decreased activity of KDR proteindecreases activity 12766257
C010643 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid results in decreased expression of KDR proteindecreases expression 17992120
D000082 Acetaminophen Acetaminophen results in increased expression of KDR mRNAincreases expression 17431590
D000082 Acetaminophen Acetaminophen results in increased expression of KDR proteinincreases expression 17431590
D000111 Acetylcysteine Acetylcysteine results in increased expression of KDR proteinincreases expression 17992120
D000638 Amiodarone Amiodarone affects the expression of KDR mRNAaffects expression 19483382
D001374 Azacitidine Azacitidine results in increased expression of KDR mRNAincreases expression 18037191
D001553 Benzbromarone Benzbromarone affects the expression of KDR mRNAaffects expression 19483382
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of KDR mRNAdecreases expression 20106945
C070515 bisindolylmaleimide I bisindolylmaleimide I inhibits the reaction [AGT protein results in increased expression of KDR mRNA]decreases reaction|increases expression 15005273
D002994 Clofibrate Clofibrate affects the expression of KDR mRNAaffects expression 19483382
D002995 Clofibric Acid [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of KDR mRNAaffects cotreatment|affects expression 17602206
D003008 Cloprostenol Cloprostenol results in decreased expression of KDR mRNAdecreases expression 14991729
D003300 Copper Copper results in decreased expression of KDR proteindecreases expression 19542178
D003474 Curcumin Curcumin affects the expression of KDR mRNAaffects expression 17960570
D003474 Curcumin Curcumin inhibits the reaction [Dietary Fats results in increased expression of KDR mRNA]decreases reaction|increases expression 19297423
D003520 Cyclophosphamide Cyclophosphamide results in decreased expression of KDR mRNAdecreases expression 19701751
D003520 Cyclophosphamide Cyclophosphamide results in decreased expression of KDR proteindecreases expression 19701751
D016572 Cyclosporine Cyclosporine results in decreased expression of KDR mRNAdecreases expression 20106945
C107676 deguelin deguelin metabolite results in decreased expression of KDR proteindecreases expression 19139008
C107676 deguelin deguelin results in decreased expression of KDR proteindecreases expression 19139008
C050229 demethoxycurcumin demethoxycurcumin affects the expression of KDR mRNAaffects expression 17960570
D004041 Dietary Fats Curcumin inhibits the reaction [Dietary Fats results in increased expression of KDR mRNA]decreases reaction|increases expression 19297423
D004041 Dietary Fats Dietary Fats results in increased expression of KDR mRNAincreases expression 19297423
18042831
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of KDR mRNAaffects cotreatment|affects expression 17602206
D004052 Diethylnitrosamine Diethylnitrosamine results in decreased expression of KDR mRNAdecreases expression 19638242
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of KDR mRNAincreases expression 17005392
C045651 epigallocatechin gallate epigallocatechin gallate results in decreased expression of KDR proteindecreases expression 17992120
D004958 Estradiol [Estradiol results in increased secretion of VEGFA protein] which results in increased expression of KDR proteinincreases expression|increases secretion 17289903
D004958 Estradiol 2,3-bis(3'-hydroxybenzyl)butane-1,4-diol inhibits the reaction [Estradiol results in increased expression of KDR protein]decreases reaction|increases expression 17289903
D004958 Estradiol 2,3-bis(3'-hydroxybenzyl)butyrolactone inhibits the reaction [Estradiol results in increased expression of KDR protein]decreases reaction|increases expression 17289903
D004958 Estradiol Estradiol results in increased expression of KDR proteinincreases expression 17289903
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of KDR mRNAdecreases expression 17557909
D005001 Ethionine Ethionine affects the expression of KDR mRNAaffects expression 19483382
D005665 Furosemide Furosemide results in increased expression of KDR mRNAincreases expression 16526316
C419708 gefitinib gefitinib inhibits the reaction [TGFA protein results in decreased expression of KDR mRNA]decreases expression|decreases reaction 18424623
D008731 Methoxychlor Methoxychlor results in increased expression of KDR proteinincreases expression 15503810
D009151 Mustard Gas IL10 protein affects the reaction [Mustard Gas affects the expression of KDR mRNA]affects expression|affects reaction 16173061
D009151 Mustard Gas Mustard Gas results in decreased expression of KDR mRNAdecreases expression 16173061
C452423 N-(4-bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine N-(4-bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine results in decreased activity of KDR proteindecreases activity 16940797
17431108
C064769 N-acetylsphingosine N-acetylsphingosine results in decreased expression of KDR mRNAdecreases expression 15741222
C064769 N-acetylsphingosine sphingosine 1-phosphate inhibits the reaction [N-acetylsphingosine results in decreased expression of KDR mRNA]decreases expression|decreases reaction 15741222
D009287 Naphthyridines Naphthyridines analog results in decreased activity of KDR proteindecreases activity 16000000
D009853 Omeprazole Omeprazole affects the expression of KDR mRNAaffects expression 19483382
C055122 orlistat orlistat results in decreased expression of KDR proteindecreases expression 17012255
D010126 Ozone Ozone results in decreased expression of KDR mRNAdecreases expression 16330353
C041786 palm oil palm oil results in increased expression of KDR mRNAincreases expression 18042831
C410127 PCB 180 [2,4,4'-trichlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of KDR mRNAaffects cotreatment|increases expression 15808785
C073402 PD 123319 PD 123319 inhibits the reaction [AGT protein results in increased expression of KDR mRNA]decreases reaction|increases expression 14638905
D010656 Phenylephrine Phenylephrine results in decreased expression of KDR mRNAdecreases expression 18158353
D010671 Phenylurea Compounds Phenylurea Compounds results in decreased activity of KDR proteindecreases activity 18343900
C068564 phosphatidylbutanol KDR protein affects the reaction [VEGFA protein results in increased abundance of phosphatidylbutanol]affects reaction|increases abundance 14704231
C006253 pirinixic acid pirinixic acid results in decreased expression of KDR mRNAdecreases expression 20059764
18445702
C006253 pirinixic acid PPARA protein promotes the reaction [pirinixic acid results in decreased expression of KDR mRNA]decreases expression|increases reaction 20059764
C006253 pirinixic acid pirinixic acid affects the expression of KDR mRNAaffects expression 19483382
D011441 Propylthiouracil Propylthiouracil affects the expression of KDR mRNAaffects expression 19483382
C059514 resveratrol resveratrol results in decreased expression of KDR proteindecreases expression 17992120
C059514 resveratrol resveratrol results in increased expression of KDR proteinincreases expression 15905131
16456233
C471405 sorafenib sorafenib results in decreased activity of KDR proteindecreases activity 16940797
C060506 sphingosine 1-phosphate sphingosine 1-phosphate inhibits the reaction [Thalidomide results in decreased expression of KDR mRNA]decreases expression|decreases reaction 15741222
C060506 sphingosine 1-phosphate sphingosine 1-phosphate inhibits the reaction [N-acetylsphingosine results in decreased expression of KDR mRNA]decreases expression|decreases reaction 15741222
C060506 sphingosine 1-phosphate sphingosine 1-phosphate inhibits the reaction [Thalidomide results in decreased expression of KDR mRNA]decreases expression|decreases reaction 15741222
D013311 Streptozocin Streptozocin results in increased expression of KDR mRNAincreases expression 15643138
D013311 Streptozocin Streptozocin results in increased expression of KDR proteinincreases expression 15643138
C483044 SU 1498 SU 1498 results in decreased activity of KDR proteindecreases activity 15845615
16385078
C116890 SU 5416 SU 5416 results in decreased activity of KDR proteindecreases activity 12673719
12649163
C116890 SU 5416 SU 5416 results in decreased activity of KDR proteindecreases activity 15788688
C412603 SU 6668 SU 6668 results in decreased phosphorylation of and results in decreased activity of KDR proteindecreases activity|decreases phosphorylation 16144927
C412603 SU 6668 SU 6668 results in decreased activity of KDR proteindecreases activity 15788688
16132614
15551349
15739567
14760097
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of KDR mRNAdecreases expression 20106945
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin affects the expression of KDR mRNAaffects expression 16962184
D013792 Thalidomide SMPD2 protein promotes the reaction [Thalidomide results in decreased expression of KDR mRNA]decreases expression|increases reaction 15741222
D013792 Thalidomide sphingosine 1-phosphate inhibits the reaction [Thalidomide results in decreased expression of KDR mRNA]decreases expression|decreases reaction 15741222
D013792 Thalidomide Thalidomide results in decreased expression of KDR mRNAdecreases expression 15741222
D013792 Thalidomide sphingosine 1-phosphate inhibits the reaction [Thalidomide results in decreased expression of KDR mRNA]decreases expression|decreases reaction 15741222
D013853 Thioacetamide Thioacetamide affects the expression of KDR mRNAaffects expression 19483382
D013893 Thiram Thiram results in decreased expression of KDR mRNAdecreases expression 17954590
D014212 Tretinoin Tretinoin results in increased expression of KDR mRNAincreases expression 17170094
D014508 Urea Urea analog results in decreased activity of KDR proteindecreases activity 16000000
C081489 valsartan valsartan inhibits the reaction [AGT protein results in increased expression of KDR mRNA]decreases reaction|increases expression 15005273
C081489 valsartan valsartan inhibits the reaction [AGT protein results in increased expression of KDR mRNA]decreases reaction|increases expression 14638905
C025643 vinclozolin vinclozolin affects the expression of KDR mRNAaffects expression 19015723
D015032 Zinc Zinc results in decreased expression of KDR mRNAdecreases expression 17074742
D019287 Zinc Sulfate Zinc Sulfate results in decreased expression of KDR mRNAdecreases expression 17074742
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D015746 Abdominal Pain SU 5416 6.4712673719
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 6.3311752688 15322242 14514962
MESH:D000014 Abnormalities, Drug-Induced Thalidomide 6.338333272
MESH:D000138 Acidosis Zinc Sulfate 4.187265320
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.2017505938
MESH:D000169 Acrodermatitis Zinc 4.6717202136 17190629 16889938
MESH:D058186 Acute Kidney Injury resveratrol 3.2116538975
MESH:D055371 Acute Lung Injury pirinixic acid 2.4518653653
MESH:D000230 Adenocarcinoma marker/mechanism 21472143
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 5.5220464547 20127859
MESH:D000230 Adenocarcinoma Estradiol 5.5211473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 5.5214692618
MESH:D000236 Adenoma Benzo(a)pyrene 8.466695378
MESH:D000236 Adenoma Diethylnitrosamine 8.466695378 10737359
MESH:D000236 Adenoma resveratrol 8.4615688382
MESH:D018248 Adenoma, Liver Cell 3,4,5,3',4'-pentachlorobiphenyl 19.0016628245
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 19.0016434500 17620307 18056438 19052882 17162532 19061943
MESH:D018248 Adenoma, Liver Cell pirinixic acid 19.0016434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 19.0016835633
MESH:D019973 Alcohol-Related Disorders Curcumin 4.3417887948
MESH:D000505 Alopecia Tretinoin 3.0215955085
MESH:D000544 Alzheimer Disease Copper 10.0416886094 16325427 16410023 17119284 16962711 16866297
MESH:D000544 Alzheimer Disease Curcumin 10.0415590663
MESH:D000544 Alzheimer Disease Ozone 10.0415513908
MESH:D000544 Alzheimer Disease resveratrol 10.0416162502 16183991
MESH:D000544 Alzheimer Disease Zinc 10.0416410023 16325427 16580781 17119284
MESH:D000686 Amyloidosis Diethylstilbestrol 3.7915469931
MESH:D000690 Amyotrophic Lateral Sclerosis Copper 6.9710694572
MESH:D000690 Amyotrophic Lateral Sclerosis Thalidomide 6.9716510725
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.3111748828
MESH:D018798 Anemia, Iron-Deficiency Copper 4.2416614410
MESH:D000755 Anemia, Sickle Cell Zinc 4.2116916123
MESH:D000799 Angioedema Acetaminophen 3.1010982225
MESH:D000860 Anoxia Zinc Sulfate 4.297265320
MESH:D001008 Anxiety Disorders vinclozolin 3.0519015723
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.3619183758
MESH:D001145 Arrhythmias, Cardiac Amiodarone 7.0218057881 18218290 20041841
MESH:D001145 Arrhythmias, Cardiac Phenylephrine 7.0217460149
MESH:D001161 Arteriosclerosis Cyclophosphamide 12.9815014928
MESH:D001161 Arteriosclerosis Dietary Fats 12.9815238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 12.9811256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 13.5215885639
MESH:D001169 Arthritis, Experimental resveratrol 13.5217115116
MESH:D001169 Arthritis, Experimental Thalidomide 13.529598899
MESH:D001169 Arthritis, Experimental Tretinoin 13.5216412693
MESH:D001172 Arthritis, Rheumatoid Curcumin 6.0416807698
MESH:D001172 Arthritis, Rheumatoid Ozone 6.0415570426
MESH:D001172 Arthritis, Rheumatoid Tretinoin 6.0416292516
MESH:D001249 Asthma epigallocatechin gallate 11.8216516891
MESH:D001249 Asthma Mustard Gas 11.8210378619
MESH:D001249 Asthma Ozone 11.8216373670 17854713
MESH:D001249 Asthma Tretinoin 11.8216456186
MESH:D001249 Asthma Zinc 11.8217085522
MESH:D050197 Atherosclerosis Curcumin 5.3318704882
MESH:D050197 Atherosclerosis resveratrol 5.3317967414 16873680
MESH:D001281 Atrial Fibrillation Amiodarone 3.3318651412 19698954
MESH:D001321 Autistic Disorder Acetaminophen 1.5418445737
MESH:D001327 Autoimmune Diseases Curcumin 8.7519761891
MESH:D001327 Autoimmune Diseases epigallocatechin gallate 8.7519761891
MESH:D001471 Barrett Esophagus Tretinoin 3.7116935849
MESH:D001768 Blister Mustard Gas 4.4319167455
MESH:D001778 Blood Coagulation Disorders Amiodarone 51.7019483382
MESH:D001778 Blood Coagulation Disorders Benzbromarone 51.7019483382
MESH:D001778 Blood Coagulation Disorders Clofibrate 51.7019483382
MESH:D001778 Blood Coagulation Disorders Ethionine 51.7019483382
MESH:D001778 Blood Coagulation Disorders Omeprazole 51.7019483382
MESH:D001778 Blood Coagulation Disorders pirinixic acid 51.7019483382
MESH:D001778 Blood Coagulation Disorders Propylthiouracil 51.7019483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 51.7012125929
MESH:D001778 Blood Coagulation Disorders Thioacetamide 51.7019483382
MESH:D001778 Blood Coagulation Disorders Tretinoin 51.7016206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.0515340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.2615746008
MESH:D001919 Bradycardia Phenylephrine 3.8215306635
MESH:D001930 Brain Injuries Zinc 3.9817109824
MESH:D002545 Brain Ischemia Curcumin 7.9216770732
MESH:D002545 Brain Ischemia resveratrol 7.9217600658
MESH:D001932 Brain Neoplasms Copper 11.4217079463
MESH:D001932 Brain Neoplasms Curcumin 11.4217596214
MESH:D001932 Brain Neoplasms SU 6668 11.4215739567
MESH:D001943 Breast Neoplasms marker/mechanism 20135347
MESH:D001943 Breast Neoplasms 2,3-bis(3'-hydroxybenzyl)butane-1,4-diol 12.1217289903
MESH:D001943 Breast Neoplasms 2,3-bis(3'-hydroxybenzyl)butyrolactone 12.1217289903
MESH:D001943 Breast Neoplasms 2-methoxyestradiol-3,17-bis-O,O-sulfamate 12.1215862969 14970876 12711013 17426705 17957467 12711022
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 12.1220146248 17474063
MESH:D001943 Breast Neoplasms Copper 12.1215986119 17079463
MESH:D001943 Breast Neoplasms Curcumin 12.1216243823 19250217 18462866 18593918
MESH:D001943 Breast Neoplasms Cyclophosphamide 12.1215093573 18234424 17020986 17388661 18323546 15136595 12006526 16978400 11325840
MESH:D001943 Breast Neoplasms deguelin 12.1218593368 17035597
MESH:D001943 Breast Neoplasms Dietary Fats 12.1220435547
MESH:D001943 Breast Neoplasms Diethylnitrosamine 12.1217474063
MESH:D001943 Breast Neoplasms Diethylstilbestrol 12.1215324884 17129689
MESH:D001943 Breast Neoplasms Estradiol 12.1217018787 12948864 17289903 18497071 19861407 16675129 14630087 17261762
MESH:D001943 Breast Neoplasms resveratrol 12.1217651959 16393696 17534123
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 12.1220435547
MESH:D001943 Breast Neoplasms Tretinoin 12.1216166294 16443354 16873071
MESH:D016535 Bronchial Hyperreactivity Ozone 3.0917626835 18417511 19059883 15516495 16777450 18315731 14754758
MESH:D001989 Bronchiolitis Obliterans Mustard Gas 4.4315286001
MESH:D029481 Bronchitis, Chronic Mustard Gas 4.2417687719 10378619
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 3.8616813970
MESH:D019121 Burkholderia Infections orlistat 5.9017874328
MESH:D002100 Cachexia Ozone 4.0116183385
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 3.7416111702
MESH:D002276 Carcinoid Tumor Streptozocin 4.8616051944
MESH:D002277 Carcinoma Curcumin 6.3218593918
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 6.3216835633
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.4216168501
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 27.5916705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 27.5916705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 27.593084413
MESH:D006528 Carcinoma, Hepatocellular Benzbromarone 27.591701930
MESH:D006528 Carcinoma, Hepatocellular Cyclophosphamide 27.5919701751
MESH:D006528 Carcinoma, Hepatocellular deguelin 27.5918575727
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 27.5916502159 18785209 16288022 19418558 16935385 20935162 17978847 20101231 17055752 17162532 19052882 16807293 17173139 19107877 16878318 19383236 10672840 16681979 18788625 20524982 16569478 20432363 20514400 18494052 19539802 18056438 18506893 18691550 17138121 16540662 20727157 11831363 19919837 20084675 20214788 19208518 19171122 18971187 18393292 16698587 17761372 19394651 3084413 18978308 19701751 10737359 16328049 19519916 18210153 17428255 3581430 18665156 21159647 16830150 19822196 20007298 19335982 20512989 16779866
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 27.5915948411 16924424
MESH:D006528 Carcinoma, Hepatocellular Estradiol 27.5916924424
MESH:D006528 Carcinoma, Hepatocellular resveratrol 27.5919321006 16227395
MESH:D006528 Carcinoma, Hepatocellular Thalidomide 27.5916313753
MESH:D006528 Carcinoma, Hepatocellular Thioacetamide 27.5917997003
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 27.591917145
MESH:D018827 Carcinoma, Lewis Lung Cyclophosphamide 9.0816152834
MESH:D018827 Carcinoma, Lewis Lung resveratrol 9.0816675471
MESH:D002289 Carcinoma, Non-Small-Cell Lung Curcumin 5.0518414057
MESH:D002289 Carcinoma, Non-Small-Cell Lung gefitinib 5.0517290066 20005069 19233551 15496427 16230376 18347146
MESH:D002292 Carcinoma, Renal Cell Cyclophosphamide 3.1416201981
MESH:D002294 Carcinoma, Squamous Cell Acetylcysteine 14.3717015178
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 14.3720419170
MESH:D002294 Carcinoma, Squamous Cell Curcumin 14.3718462866
MESH:D002294 Carcinoma, Squamous Cell resveratrol 14.3716227395
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 14.3716096774 16051514
MESH:D002294 Carcinoma, Squamous Cell Zinc 14.3716543248
MESH:D006332 Cardiomegaly Copper 12.6717327471
MESH:D006332 Cardiomegaly Phenylephrine 12.6717124262 17287366 11179087 11754973 15728586 16170337
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 12.6718850075 18670907 16120746
MESH:D006332 Cardiomegaly valsartan 12.6719597038
MESH:D009202 Cardiomyopathies valsartan 3.9316247790
MESH:D002311 Cardiomyopathy, Dilated Amiodarone 2.5919225199 15710769
MESH:D002318 Cardiovascular Diseases resveratrol 9.3115458977
MESH:D002318 Cardiovascular Diseases valsartan 9.3111230374
MESH:D002318 Cardiovascular Diseases Zinc 9.3116936243
MESH:D002341 Carotid Artery Thrombosis Amiodarone 4.3618974383
MESH:D002386 Cataract Acetaminophen 5.6410977129
MESH:D002386 Cataract Tretinoin 5.6417460283
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 19.486135515
MESH:D002471 Cell Transformation, Neoplastic Acetylcysteine 19.4818226522
MESH:D002471 Cell Transformation, Neoplastic Clofibrate 19.481399818
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 19.4812371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 19.4817174075 7505956 21159647 2727394
MESH:D002471 Cell Transformation, Neoplastic Estradiol 19.4818566989
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 3.8616129372
MESH:D002637 Chest Pain Omeprazole 4.3715447763
MESH:D018281 Cholangiocarcinoma 3,4,5,3',4'-pentachlorobiphenyl 23.6916628245
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 23.6919052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 23.6916835633
MESH:D018281 Cholangiocarcinoma Thalidomide 23.6918291259
MESH:D018281 Cholangiocarcinoma Thioacetamide 23.6918291259
MESH:D002779 Cholestasis Cyclosporine 10.0819486331
MESH:D002779 Cholestasis Ethinyl Estradiol 10.0816105132 11677210 16919318 17110522 17681005 17333356 15861022
MESH:D002779 Cholestasis pirinixic acid 10.0819176532
MESH:D002822 Choriocarcinoma Tretinoin 4.4216461808
MESH:D002916 Chylothorax orlistat 5.9017003701
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 4.5316354765 8697196 12621046 15340226 15668235
MESH:D002972 Cleft Palate Tretinoin 4.539407595
MESH:D003092 Colitis Curcumin 17.1316804969 16782535 18200517
MESH:D003092 Colitis resveratrol 17.1316474422
MESH:D003092 Colitis Thalidomide 17.1316680017
MESH:D003092 Colitis Tretinoin 17.1317035595
MESH:D003103 Coloboma Curcumin 3.8918809619
MESH:D003110 Colonic Neoplasms Curcumin 3.3819359593 16340194
MESH:D003110 Colonic Neoplasms resveratrol 3.3816338953
MESH:D015179 Colorectal Neoplasms Azacitidine 3.2219934284
MESH:D015179 Colorectal Neoplasms gefitinib 3.2217594712
MESH:D015179 Colorectal Neoplasms resveratrol 3.2216550006
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.4417141729 14669216
MESH:D016510 Corneal Neovascularization Curcumin 10.2518497527
MESH:D016510 Corneal Neovascularization Thalidomide 10.259301478
MESH:D003324 Coronary Artery Disease valsartan 3.5817719468
MESH:D003327 Coronary Disease resveratrol 3.2516507316
MESH:D003384 Coxsackievirus Infections valsartan 5.1120392896
MESH:D003389 Cranial Nerve Diseases Thalidomide 5.569200351
MESH:D019465 Craniofacial Abnormalities 3,4,5,3',4'-pentachlorobiphenyl 6.0317686920
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 6.0310048152 15322242 20055451
MESH:D019465 Craniofacial Abnormalities Thalidomide 6.039200351
MESH:D019465 Craniofacial Abnormalities Tretinoin 6.039125849 16925845 9211117 9142499 8800419 10589399 9664655 17551590 9224671 14991402
MESH:D019465 Craniofacial Abnormalities Zinc 6.0319302082
MESH:D003424 Crohn Disease Thalidomide 3.7616078585
MESH:D003456 Cryptorchidism Diethylstilbestrol 9.0716002989 12952375
MESH:D003456 Cryptorchidism vinclozolin 9.0714966744
MESH:D003490 Cyanosis 2,4-dinitrotoluene 8.5418551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 8.5418551238
MESH:D003550 Cystic Fibrosis Acetylcysteine 3.7519747007
MESH:D003556 Cystitis Cyclophosphamide 4.2512161096 16413132 11948286 12388444 16651033 18372110 18295254 18093676 18710439 18433785 16989017 12913760 18483878 10498854 10700343 15276878 17010015 15643279 17979934 16614059
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.0318249437
MESH:D002658 Developmental Disabilities 2,3',4,4',5-pentachlorobiphenyl 4.9319647017
MESH:D048909 Diabetes Complications orlistat 5.1019207292
MESH:D003920 Diabetes Mellitus Streptozocin 7.6716285004
MESH:D003920 Diabetes Mellitus Zinc 7.6716479319
MESH:D003921 Diabetes Mellitus, Experimental Cyclophosphamide 14.9810990075 11751995 15331540
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 14.9816873680
MESH:D003921 Diabetes Mellitus, Experimental Streptozocin 14.987637645 12093613 15862027 17442507 2177838 19960420 19496084 19298542 16684804 18715473 12446591 12644472 18603373 6379147 16286809 11260395 15298345 12083368 11055810 15831366 1374869 8740154 17874149 19586609
MESH:D003921 Diabetes Mellitus, Experimental valsartan 14.9811508273
MESH:D003922 Diabetes Mellitus, Type 1 Cyclophosphamide 5.1018772604
MESH:D003922 Diabetes Mellitus, Type 1 Streptozocin 5.1018603373
MESH:D003924 Diabetes Mellitus, Type 2 Curcumin 10.9718403477
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 10.9720387270
MESH:D003924 Diabetes Mellitus, Type 2 epigallocatechin gallate 10.9716988119
MESH:D003924 Diabetes Mellitus, Type 2 Streptozocin 10.9719586609 19647726
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 10.9717107852
MESH:D058065 Diabetic Cardiomyopathies Streptozocin 5.0016025228
MESH:D003928 Diabetic Nephropathies marker/mechanism 18630688
MESH:D003928 Diabetic Nephropathies Curcumin 21.5418204486
MESH:D003928 Diabetic Nephropathies Estradiol 21.5419279558
MESH:D003928 Diabetic Nephropathies resveratrol 21.5416286809
MESH:D003928 Diabetic Nephropathies Streptozocin 21.5419682444 19960420
MESH:D003928 Diabetic Nephropathies valsartan 21.5411427623 18630688
MESH:D003930 Diabetic Retinopathy Streptozocin 4.7317662242
MESH:D003967 Diarrhea orlistat 6.9420002075
MESH:D003967 Diarrhea SU 5416 6.9412673719
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 17.1021346803 18551238
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 17.1018551238 21346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 17.1017562736 18071297 16393943 11461765 12540782 19416960 12392966 17906064 19420014 17522070 14550746 14725611 11529661 11421492 10663392 16781746 12594235 11287661 19164858 19739265 18713872 15968718 19370779 12705907 16485898 12958197 12153990 10915739 11739529 16227642 11743745 19085960 15619225 11834606 2444490 16081117 16177239 14986274 19923254 16109766 10774834
MESH:D056486 Drug-Induced Liver Injury Acetylcysteine 17.1011287661
MESH:D056486 Drug-Induced Liver Injury Amiodarone 17.1018218290 15265979
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 17.1019107877
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 17.1020420201
MESH:D056486 Drug-Induced Liver Injury Thioacetamide 17.1012963478
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.3619426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.2011462148
MESH:D004381 Duodenal Ulcer Curcumin 7.2117351913
MESH:D004381 Duodenal Ulcer Omeprazole 7.2121218061 16613094 15991576 17151854
MESH:D050171 Dyslipidemias Clofibrate 6.9816707586
MESH:D050171 Dyslipidemias Dietary Fats 6.9818367378
MESH:D004417 Dyspnea Furosemide 8.7616935035
MESH:D004417 Dyspnea SU 5416 8.7612673719 12649163
MESH:D004487 Edema bisindolylmaleimide I 22.748273558
MESH:D004487 Edema demethoxycurcumin 22.7418449507
MESH:D004487 Edema Furosemide 22.7411834646
MESH:D004487 Edema Mustard Gas 22.749260866 11402378 11428631 11428647
MESH:D004487 Edema pirinixic acid 22.7412083418
MESH:D004487 Edema resveratrol 22.748985016
MESH:D004487 Edema Tetrachlorodibenzodioxin 22.7412711302 11000095
MESH:D004489 Edema, Cardiac 3,4,5,3',4'-pentachlorobiphenyl 16.8317686920
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 16.8318230668 15322242 16714409
MESH:D004489 Edema, Cardiac Tretinoin 16.8318230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 6.8412538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 6.8417872969
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 3.9716402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 9.5016804899 15700306
MESH:D016889 Endometrial Neoplasms Estradiol 9.5018566989 11473722 19148513
MESH:D016889 Endometrial Neoplasms Tretinoin 9.5016569247
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.3910568697 9294722
MESH:D020345 Enterocolitis, Necrotizing resveratrol 4.1417923197
MESH:D004802 Eosinophilia Cyclophosphamide 3.5211006010
MESH:D004890 Erythema Mustard Gas 4.439357497
MESH:D004892 Erythema Multiforme Thiram 5.9116750123
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.3816302075
MESH:D004938 Esophageal Neoplasms marker/mechanism 21472143
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 3.8016530937
MESH:D004938 Esophageal Neoplasms Zinc 3.8016543248
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 6.9511564622
MESH:D005124 Eye Abnormalities Tretinoin 6.9516938888 9664655
MESH:D005221 Fatigue SU 5416 5.6612673719 12649163
MESH:D005218 Fat Necrosis Thioacetamide 4.9816456712
MESH:D005234 Fatty Liver Amiodarone 31.9114986274
MESH:D005234 Fatty Liver Clofibrate 31.9119224547
MESH:D005234 Fatty Liver Curcumin 31.9119297423
MESH:D005234 Fatty Liver Cyclosporine 31.9119224547
MESH:D005234 Fatty Liver Dietary Fats 31.9117967931 19551842 19004024 18296743
MESH:D005234 Fatty Liver Diethylnitrosamine 31.9121071580 20387270
MESH:D005234 Fatty Liver Ethinyl Estradiol 31.9115345470
MESH:D005234 Fatty Liver pirinixic acid 31.9120131406 19236843
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 3.1716534752 16513791 15751030 16611131 16002989
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 2.7511858732
MESH:D005355 Fibrosis Curcumin 25.4218705752
MESH:D005355 Fibrosis Cyclosporine 25.4212168785 12639820
MESH:D005355 Fibrosis Dietary Fats 25.4218296743
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 25.4220067830
MESH:D005355 Fibrosis Tretinoin 25.4217994277
MESH:D005355 Fibrosis valsartan 25.4216893502
MESH:D005414 Flatulence orlistat 5.9020002075
MESH:D005756 Gastritis Acetaminophen 8.7116983495
MESH:D005756 Gastritis Zinc 8.7117241300
MESH:D005770 Gastrointestinal Neoplasms Curcumin 3.9818462866
MESH:D030342 Genetic Diseases, Inborn vinclozolin 4.2116973722
MESH:D005832 Genital Diseases, Male vinclozolin 4.5616417039
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 4.2216452187
MESH:D005871 Giant Lymph Node Hyperplasia Thalidomide 5.5612701121
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.498708960
MESH:D005909 Glioblastoma Curcumin 5.5917596214
MESH:D005909 Glioblastoma Tretinoin 5.5917312396
MESH:D005910 Glioma SU 6668 6.1215739567
MESH:D005910 Glioma Thalidomide 6.1216327979
MESH:D018316 Gliosarcoma Cyclophosphamide 4.7911389073
MESH:D015432 Glomerulonephritis, Membranoproliferative valsartan 4.8516928621
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 3.8510696789
MESH:D006086 Graft vs Host Disease Cyclophosphamide 4.3216376943 11014644 15172196
MESH:D006130 Growth Disorders Zinc 3.4517217573
MESH:D006261 Headache SU 5416 5.3212649163 12673719
MESH:D006258 Head and Neck Neoplasms Curcumin 6.1418462866 18829502
MESH:D006258 Head and Neck Neoplasms Tretinoin 6.1416096774
MESH:D034381 Hearing Loss Furosemide 4.2017868369
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.4216084493
MESH:D006330 Heart Defects, Congenital 3,4,3',4'-tetrachlorobiphenyl 16.4311294989
MESH:D006330 Heart Defects, Congenital 3,4,5,3',4'-pentachlorobiphenyl 16.4317686920 20471113
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 16.4320471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 16.4311294989 10048152
MESH:D006330 Heart Defects, Congenital Tretinoin 16.4314991402 9664655
MESH:D006331 Heart Diseases Streptozocin 3.7512093613
MESH:D006333 Heart Failure Furosemide 12.9412660669 16011733 16845234
MESH:D006333 Heart Failure pirinixic acid 12.9420558911
MESH:D006333 Heart Failure valsartan 12.9419027736
MESH:D006333 Heart Failure Zinc 12.9417162251
MESH:D006335 Heart Injuries Zinc 5.0317074742
MESH:D016481 Helicobacter Infections Zinc 3.8617241300
MESH:C535860 Hemangioma, capillary infantile marker/mechanism
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 3.6915720958
MESH:D006467 Hemophilia A Cyclophosphamide 4.5811918545
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.6811000095
MESH:D006501 Hepatic Encephalopathy Thioacetamide 3.9118665440 17276928 15929193
MESH:D006504 Hepatic Veno-Occlusive Disease Cyclophosphamide 4.7914986274
MESH:D006505 Hepatitis Thioacetamide 3.5316456712
MESH:D006521 Hepatitis, Chronic Copper 4.5417338147
MESH:D006527 Hepatolenticular Degeneration Copper 14.5617276780 19888908 17109627 16607473 17182432
MESH:D006527 Hepatolenticular Degeneration Zinc 14.5617276780
MESH:D006527 Hepatolenticular Degeneration Zinc Sulfate 14.5617063115
MESH:D006529 Hepatomegaly Amiodarone 10.3515265979
MESH:D006529 Hepatomegaly pirinixic acid 10.3519176532 16221962 19772884 18467677
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 10.3515340226 12621046 16120746
MESH:D015417 Hereditary Sensory and Motor Neuropathy Curcumin 4.3317701891
MESH:D006558 Herpes Genitalis Estradiol 4.2915709030
MESH:D006561 Herpes Simplex resveratrol 3.4616876885
MESH:D006689 Hodgkin Disease Cyclophosphamide 3.1917606976 16135485
MESH:D019584 Hot Flashes Estradiol 3.0217088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.3015340226 16354765 16959395 18606429 8697196
MESH:D006930 Hyperalgesia Acetaminophen 5.6716870215
MESH:D006930 Hyperalgesia Tretinoin 5.6716870215
MESH:D006934 Hypercalcemia Furosemide 4.4117652376
MESH:D053565 Hypercalciuria Furosemide 4.9217652376
MESH:D006937 Hypercholesterolemia Amiodarone 16.469751232 8137927
MESH:D006937 Hypercholesterolemia Curcumin 16.4618704882
MESH:D006937 Hypercholesterolemia Dietary Fats 16.4621332399
MESH:D006937 Hypercholesterolemia resveratrol 16.4617188708
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 3.8616778211
MESH:D006943 Hyperglycemia pirinixic acid 2.5520558911
MESH:D006949 Hyperlipidemias Dietary Fats 11.7621332399
MESH:D006949 Hyperlipidemias orlistat 11.7621332399
MESH:D006949 Hyperlipidemias resveratrol 11.7616873680
MESH:D006962 Hyperparathyroidism, Secondary Furosemide 5.1315086907
MESH:D006965 Hyperplasia Diethylstilbestrol 3.7312960047 14722030
MESH:D006973 Hypertension Cyclosporine 9.5810903974
MESH:D006973 Hypertension Phenylephrine 9.5812717712 8949925
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 9.5818670907 18850075
MESH:D006973 Hypertension valsartan 9.5810903974 18344623 16475468 20102058 11427623 18390891 12692753 12850387
MESH:D006974 Hypertension, Malignant valsartan 5.6711560862
MESH:D046110 Hypertension, Pregnancy-Induced Furosemide 4.5716612254
MESH:D006976 Hypertension, Pulmonary gefitinib 4.1518424623
MESH:D006984 Hypertrophy Phenylephrine 3.9018502941 12791704
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 3.6617488730
MESH:D017380 Hypertrophy, Right Ventricular gefitinib 5.5118424623
MESH:C537153 Hypomagnesemia primary Furosemide 4.9211041285
MESH:D007019 Hypoproteinemia Furosemide 5.1316096441
MESH:D007021 Hypospadias Diethylstilbestrol 8.8916002989
MESH:D007021 Hypospadias Ethinyl Estradiol 8.8916945680 16569931
MESH:D007022 Hypotension Furosemide 7.4611041285
MESH:D007022 Hypotension Zinc Sulfate 7.467265320
MESH:D007024 Hypotension, Orthostatic Furosemide 4.6815811171
MESH:D007037 Hypothyroidism Amiodarone 9.2518020914 17991464
MESH:D007037 Hypothyroidism Propylthiouracil 9.258137927 18031379
MESH:D007154 Immune System Diseases Cyclophosphamide 4.5916076520
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 3.9417600658
MESH:D007246 Infertility Diethylstilbestrol 8.9815036965
MESH:D007246 Infertility Thiram 8.986420938
MESH:D007247 Infertility, Female Ethinyl Estradiol 2.7912013081
MESH:D007248 Infertility, Male 2,2',3',4,4',5-hexachlorobiphenyl 15.6612948891
MESH:D007248 Infertility, Male Cyclophosphamide 15.6616517039 7193160
MESH:D007248 Infertility, Male Ethinyl Estradiol 15.6617937319
MESH:D007248 Infertility, Male Methoxychlor 15.6611955947 16467254
MESH:D007248 Infertility, Male vinclozolin 15.6616467254
MESH:D007249 Inflammation bisindolylmaleimide I 20.998273558
MESH:D007249 Inflammation Curcumin 20.9918403477 17151092 16956363
MESH:D007249 Inflammation Dietary Fats 20.9920412841
MESH:D007249 Inflammation Diethylnitrosamine 20.9918785209
MESH:D007249 Inflammation Mustard Gas 20.9917524151 11402378 9260866 9357497 11428620 16001271 8975870 11428647 11428631
MESH:D007249 Inflammation resveratrol 20.9916366677
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 20.9912878042 12200463
MESH:D007249 Inflammation Thalidomide 20.9916134734
MESH:D015212 Inflammatory Bowel Diseases Curcumin 2.8618596194 18200517
MESH:D007251 Influenza, Human resveratrol 3.8116624496
MESH:D007333 Insulin Resistance Dietary Fats 13.4818457598 11836018
MESH:D007333 Insulin Resistance Estradiol 13.4816393666 16627594
MESH:D007333 Insulin Resistance orlistat 13.4817201808
MESH:D007333 Insulin Resistance pirinixic acid 13.4816306350
MESH:D007410 Intestinal Diseases Tretinoin 3.0617994277
MESH:D007414 Intestinal Neoplasms Curcumin 3.5810783313
MESH:D007511 Ischemia Zinc 3.9216584753
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 7.7516580747
MESH:D007569 Jaw Abnormalities Tretinoin 7.7515992940 17551590
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 3.7015604871
MESH:D007674 Kidney Diseases Acetaminophen 21.6912587719 15629191
MESH:D007674 Kidney Diseases Cyclosporine 21.698314463 10903974 18776723
MESH:D007674 Kidney Diseases Estradiol 21.6915618244
MESH:D007674 Kidney Diseases Furosemide 21.6911041285
MESH:D007674 Kidney Diseases Streptozocin 21.6912093613
MESH:D007674 Kidney Diseases valsartan 21.6916893502 12164870 10903974
MESH:D007674 Kidney Diseases Zinc 21.6916960431
MESH:C531755 Kidney disorder involving deposition of calcium and oxalate or phosphate in the renal tubules orlistat 5.9017185156
MESH:D007676 Kidney Failure, Chronic Copper 8.2716518626
MESH:D007676 Kidney Failure, Chronic Zinc 8.2716518626
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 21.3316705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 21.3316705839
MESH:D007680 Kidney Neoplasms Cyclosporine 21.3312371664
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 21.3315003126 14681315 16762066
MESH:D007680 Kidney Neoplasms Estradiol 21.3315610895
MESH:D007680 Kidney Neoplasms gefitinib 21.3318625569
MESH:D007859 Learning Disorders Copper 7.6617134702
MESH:D007859 Learning Disorders Diethylstilbestrol 7.6617184923
MESH:D007889 Leiomyoma Curcumin 3.9018555241
MESH:D016773 Leishmaniasis, Cutaneous Omeprazole 6.8619248655
MESH:D016773 Leishmaniasis, Cutaneous Zinc Sulfate 6.8615237267
MESH:D007898 Leishmaniasis, Visceral Thalidomide 3.7716514283
MESH:D007938 Leukemia Azacitidine 11.5719148494
MESH:D007938 Leukemia Curcumin 11.5718462866
MESH:D007938 Leukemia Cyclophosphamide 11.5710602166
MESH:D007938 Leukemia Tretinoin 11.5717143497
MESH:D015451 Leukemia, Lymphocytic, Chronic, B-Cell Cyclophosphamide 3.1317802794 17008537 17296974 18172266 17658394 18587576
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Curcumin 3.5516106398
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Cyclophosphamide 3.5310373061
MESH:D007951 Leukemia, Myeloid Azacitidine 7.6119077051
MESH:D007951 Leukemia, Myeloid Tretinoin 7.6116932348 19285840 16482212
MESH:D015470 Leukemia, Myeloid, Acute Azacitidine 7.2917596541 18720364
MESH:D015470 Leukemia, Myeloid, Acute SU 5416 7.2912649163
MESH:D015470 Leukemia, Myeloid, Acute Thalidomide 7.2918720364
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 7.2919850784 16294345 17596541
MESH:D054429 Leukemia, Myelomonocytic, Juvenile Azacitidine 4.5119299654
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 6.0516087638
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 6.0516891316 17506722 17712046 16766008 17649720 19029980 17107899 19035177 16788101 16140955 17339181 16935935 19642359 17301526 17294898 16331271 16823087 15748426 19075265 12679006 9834237 17368321 17361223 17217047 19225113
MESH:D015458 Leukemia, T-Cell Curcumin 4.0716106398
MESH:D007970 Leukopenia Cyclophosphamide 4.2411830472 10052129
MESH:D007984 Leydig Cell Tumor vinclozolin 4.0016417039
MESH:D017880 Limb Deformities, Congenital Thalidomide 6.7210473037
MESH:D017880 Limb Deformities, Congenital Tretinoin 6.729224671
MESH:D008064 Lipidoses Amiodarone 2.9715342952 17567588
MESH:D008103 Liver Cirrhosis Dietary Fats 12.1518296743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 12.1518665156 18407596 20032147 18522880 19638242
MESH:D008103 Liver Cirrhosis orlistat 12.1517404856
MESH:D008103 Liver Cirrhosis Thalidomide 12.1516943688 17174718
MESH:D008106 Liver Cirrhosis, Experimental Curcumin 12.8318006644 18705752 17355460
MESH:D008106 Liver Cirrhosis, Experimental epigallocatechin gallate 12.8317481882
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 12.8314716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 12.8315474484
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 12.8312878042
MESH:D008106 Liver Cirrhosis, Experimental Thalidomide 12.8315465738
MESH:D008106 Liver Cirrhosis, Experimental Thioacetamide 12.8312891558 15316131 14739098 18295389 10677585 18031379 17050028 17355460 15362042 18458672 15334695 15078482 12679928 18380797 12175628 15095483 15465738 11682029 16489207 15075984 16097051 18416461 15288473 16126171 16098781 11172339 17127702 15716488 12085344 18032466 18615449 15158331 18263696 17629604 18606216 11481614 16511523 16343077 12557150 17292413 18395095 15474484 16248980 15288472 12531686
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 12.8318397230 16248980
MESH:D008106 Liver Cirrhosis, Experimental valsartan 12.8316872305 15619341 15504291
MESH:D008107 Liver Diseases Acetaminophen 7.2612969438 11587558 19460945 16611625 19784758 16610002 19014921 12587719
MESH:D008107 Liver Diseases Curcumin 7.2616956363
MESH:D008107 Liver Diseases Diethylnitrosamine 7.2617034775
MESH:D008107 Liver Diseases Thioacetamide 7.2618374380 15158337 16337175
MESH:D017114 Liver Failure, Acute Acetaminophen 7.5117185352 16871587
MESH:D017114 Liver Failure, Acute Thioacetamide 7.5115633222 12479984 15313186 17276928
MESH:D008113 Liver Neoplasms 2,4,5,2',4',5'-hexachlorobiphenyl 26.7516835634 18644402
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 26.757678174
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 26.7520195826 21137059
MESH:D008113 Liver Neoplasms Clofibric Acid 26.7517602206
MESH:D008113 Liver Neoplasms Copper 26.7520302851
MESH:D008113 Liver Neoplasms Diethylnitrosamine 26.7520501860 19638242 20118626 19426721 15885732 18977376 18978307 18648771 19256749 12112319 19996281 19254457 21167192 19690152 2862719 12771043 20405173 18644402 20492335 20137499 21071580 20452335 10737359 20101389 20583210 19499222 19255062 18754104 2422723 21278145 19427195 19812893 19090486 15175105 9163691 19294768 19850985 19833225 16942905 19073162 20434301 21047994 19642983 19551842
MESH:D008113 Liver Neoplasms Diethylstilbestrol 26.7516712894 15890375
MESH:D008113 Liver Neoplasms pirinixic acid 26.7515890375 20007298 16377806
MESH:D008113 Liver Neoplasms resveratrol 26.7519812893 19073162 20405173 19321006
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 26.7516984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 6.932876784 6135515 2876786
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 6.9319126423 16267830 17174075 18544905 21159647 19539802 19519916 18079962 18308698 18093689 18164116 19009564 9362446 18775883 18253720 3124819 19004024 17942915 18282651 17854601 16842330 2563599
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 6.9312151625
MESH:D008133 Long QT Syndrome Amiodarone 3.0111989578 15350150 17391786
MESH:D008171 Lung Diseases Acetylcysteine 13.3512815614
MESH:D008171 Lung Diseases Amiodarone 13.3512587719
MESH:D008171 Lung Diseases Mustard Gas 13.3518702808 18161513
MESH:D008171 Lung Diseases Ozone 13.358266340 19066396
MESH:D017563 Lung Diseases, Interstitial Amiodarone 3.7418516814
MESH:D055370 Lung Injury Ozone 3.1520417186
MESH:D008175 Lung Neoplasms Azacitidine 10.5021224363
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 10.5018569708 20869020 18816296 17053015 18520028 20064080 6695378 20135361 20464547
MESH:D008175 Lung Neoplasms Curcumin 10.5018462866 19359593 16243823
MESH:D008175 Lung Neoplasms deguelin 10.5019336726 16288123
MESH:D008175 Lung Neoplasms Diethylnitrosamine 10.5020512841 20970405 21163286 6695378
MESH:D008175 Lung Neoplasms Mustard Gas 10.508781369 3148597
MESH:D008175 Lung Neoplasms Ozone 10.507614698 8597069
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 10.5011884234 19555203
MESH:D008181 Lupus Nephritis Diethylstilbestrol 4.4215166399
MESH:D008207 Lymphatic Metastasis orlistat 5.1920805790 18770866
MESH:D008223 Lymphoma Curcumin 9.5318462866
MESH:D008223 Lymphoma Cyclophosphamide 9.5312854902
MESH:D008223 Lymphoma Diethylstilbestrol 9.5315700306
MESH:D016393 Lymphoma, B-Cell Cyclophosphamide 8.2316675587
MESH:D016393 Lymphoma, B-Cell resveratrol 8.2317088997
MESH:D008228 Lymphoma, Non-Hodgkin Cyclophosphamide 7.0011911406
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 7.0014749477
MESH:D016399 Lymphoma, T-Cell Curcumin 3.9816173963
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 4.7716002989
MESH:D015674 Mammary Neoplasms, Animal resveratrol 3.5315688416
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 10.2317203775 11807958 11408345 16891317
MESH:D008325 Mammary Neoplasms, Experimental gefitinib 10.2318375820
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 10.2311606380 8985016
MESH:D008325 Mammary Neoplasms, Experimental Zinc 10.2312773700
MESH:D020149 Manganese Poisoning Estradiol 3.7419453300
MESH:D008527 Medulloblastoma Tretinoin 2.4417453147
MESH:D008545 Melanoma 2-methoxyestradiol-3,17-bis-O,O-sulfamate 17.7114970876
MESH:D008545 Melanoma 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid 17.7117992120
MESH:D008545 Melanoma Curcumin 17.7118462866 17885582
MESH:D008545 Melanoma epigallocatechin gallate 17.7111746506 17992120
MESH:D008545 Melanoma orlistat 17.7118770866 20805790
MESH:D008545 Melanoma resveratrol 17.7117992120
MESH:D008545 Melanoma sorafenib 17.7118445842
MESH:D008545 Melanoma Thalidomide 17.7117089043 16098027 12829675
MESH:D008545 Melanoma Tretinoin 17.7116752155
MESH:D008546 Melanoma, Experimental Acetaminophen 8.4819513568
MESH:D008546 Melanoma, Experimental Cyclophosphamide 8.4816388313
MESH:D008569 Memory Disorders Curcumin 3.4717263510
MESH:D008591 Meningomyelocele Tretinoin 3.7116940565
MESH:D007706 Menkes Kinky Hair Syndrome Copper 5.1517268249 17109627
MESH:D008659 Metabolic Diseases resveratrol 3.7217112576
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.0516801185
MESH:D008679 Metaplasia Ozone 4.3610496685
MESH:D009006 Monosomy Azacitidine 5.3419299654
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 2.6116381670
MESH:D009101 Multiple Myeloma Azacitidine 12.9019549372 18443271
MESH:D009101 Multiple Myeloma Curcumin 12.9019372569
MESH:D009101 Multiple Myeloma resveratrol 12.9017049120 17935668 16490592 14749477 17164350 16267019
MESH:D009101 Multiple Myeloma Thalidomide 12.9016445831 15867202 15744524 19112201 15939924 17168659 19372569 19112817 15920492 15741222
MESH:D009134 Muscular Atrophy, Spinal Curcumin 16.9617962980
MESH:D009134 Muscular Atrophy, Spinal epigallocatechin gallate 16.9617962980
MESH:D009134 Muscular Atrophy, Spinal resveratrol 16.9617962980
MESH:D009135 Muscular Diseases orlistat 8.3918430571
MESH:D009135 Muscular Diseases pirinixic acid 8.3916239165
MESH:D009164 Mycobacterium Infections orlistat 4.7621442799
MESH:D009181 Mycoses Amiodarone 4.1612754197 17974566
MESH:D009190 Myelodysplastic Syndromes Azacitidine 13.9217611569 19805378 17596541 18720364
MESH:D009190 Myelodysplastic Syndromes SU 5416 13.9212649163
MESH:D009190 Myelodysplastic Syndromes Thalidomide 13.9218720364
MESH:D009190 Myelodysplastic Syndromes Tretinoin 13.9217596541
MESH:D009203 Myocardial Infarction pirinixic acid 4.5219151258
MESH:D009203 Myocardial Infarction resveratrol 4.5217188708 16456233 16525036 17015251 16317513 17125593
MESH:D017202 Myocardial Ischemia resveratrol 7.0317015251 17125593
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 7.0312213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 6.3316810080
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 6.3316411023
MESH:D009205 Myocarditis resveratrol 4.0317322642
MESH:D009336 Necrosis 2,4-dinitrotoluene 7.9418551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 7.947678174 18551238
MESH:D009361 Neoplasm Invasiveness Curcumin 8.6818495463
MESH:D009361 Neoplasm Invasiveness demethoxycurcumin 8.6818495463
MESH:D009362 Neoplasm Metastasis Acetylcysteine 4.9214720322
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 4.929029167 3581430
MESH:D009369 Neoplasms 2,4,5,2',4',5'-hexachlorobiphenyl 24.588820588
MESH:D009369 Neoplasms Benzo(a)pyrene 24.5811141357
MESH:D009369 Neoplasms Cyclophosphamide 24.5818854779
MESH:D009369 Neoplasms deguelin 24.5817764071
MESH:D009369 Neoplasms Diethylstilbestrol 24.5815313581
MESH:D009369 Neoplasms orlistat 24.5818710210
MESH:D009369 Neoplasms pirinixic acid 24.5817405874
MESH:D009369 Neoplasms SU 5416 24.5817264769
MESH:D009369 Neoplasms Tretinoin 24.5816946489 16594593
MESH:D009374 Neoplasms, Experimental orlistat 7.4019381703
MESH:D009374 Neoplasms, Experimental resveratrol 7.408985016
MESH:D009376 Neoplasms, Hormone-Dependent Curcumin 3.8012497104
MESH:D009389 Neovascularization, Pathologic 2,3-bis(3'-hydroxybenzyl)butane-1,4-diol 30.1617289903
MESH:D009389 Neovascularization, Pathologic 2,3-bis(3'-hydroxybenzyl)butyrolactone 30.1617289903
MESH:D009389 Neovascularization, Pathologic 2-methoxyestradiol-3,17-bis-O,O-sulfamate 30.1617426705
MESH:D009389 Neovascularization, Pathologic Copper 30.1617308104
MESH:D009389 Neovascularization, Pathologic Estradiol 30.1617289903
MESH:D009389 Neovascularization, Pathologic orlistat 30.1617012255
MESH:D009397 Nephrocalcinosis Furosemide 5.1315086907
MESH:D009402 Nephrosis, Lipoid Cyclosporine 3.7017954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 2.6619348381 18481113
MESH:D009421 Nervous System Malformations Diethylstilbestrol 23.4811399458
MESH:D009421 Nervous System Malformations Estradiol 23.4816427766 11399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 23.4814600291
MESH:D009421 Nervous System Malformations Thalidomide 23.4816859833
MESH:D009421 Nervous System Malformations Tretinoin 23.489125849
MESH:D009423 Nervous System Neoplasms Curcumin 4.8918462866
MESH:D009436 Neural Tube Defects Acetylcysteine 5.9319446573
MESH:D009436 Neural Tube Defects Tretinoin 5.939142499
MESH:D019954 Neurobehavioral Manifestations 2,3',4,4',5-pentachlorobiphenyl 5.8019647017
MESH:D009447 Neuroblastoma Cyclophosphamide 3.228761367 15176712 16115947
MESH:D019636 Neurodegenerative Diseases Acetaminophen 10.5518514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 10.5520387270
MESH:D019636 Neurodegenerative Diseases resveratrol 10.5517652729
MESH:D017599 Neuroectodermal Tumors Cyclophosphamide 4.168761367 12837982
MESH:D020078 Neurogenic Inflammation resveratrol 3.7217929310
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.3820387270
MESH:D009503 Neutropenia Cyclophosphamide 7.308291058
MESH:D009503 Neutropenia Mustard Gas 7.307688884 16761898
MESH:D052556 Niemann-Pick Disease, Type C Clofibrate 4.239802331
MESH:D053206 Nocturnal Enuresis Furosemide 5.1317945291
MESH:C541083 Non-alcoholic Fatty Liver Disease orlistat 4.9017404856
MESH:D009765 Obesity Curcumin 8.6219297423
MESH:D009765 Obesity Dietary Fats 8.6217217161 11836018 18674790 20132043 21332399 18457598 16723640 20518802 19632207
MESH:D009765 Obesity orlistat 8.6216938137 21438711 20518802 21442799 19207292 20540997 18773755 20599501 20002075 19461584 19046740 20065556
MESH:D009765 Obesity pirinixic acid 8.6220558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 6.7612819281 16049721
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 6.7616049721
MESH:D009845 Oligospermia Cyclophosphamide 3.9916517039
MESH:D010009 Osteochondrodysplasias marker/mechanism 17954590
MESH:D010009 Osteochondrodysplasias Thiram 4.9515518828 15899490 17954590
MESH:D010024 Osteoporosis Curcumin 2.9918719352
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 3.5817513867
MESH:D010051 Ovarian Neoplasms Curcumin 8.8719020741 18462866
MESH:D010051 Ovarian Neoplasms Estradiol 8.8719401270
MESH:D010051 Ovarian Neoplasms Thalidomide 8.8716288038
MESH:D010051 Ovarian Neoplasms Tretinoin 8.8716936753
MESH:D010146 Pain Acetaminophen 7.8416870215
MESH:D010146 Pain Cyclophosphamide 7.8412161096 18093676
MESH:D010146 Pain Tretinoin 7.8416870215
MESH:D010190 Pancreatic Neoplasms Curcumin 9.6419401701 19196508 17440100
MESH:D010190 Pancreatic Neoplasms Cyclophosphamide 9.6411332152
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 9.6416540662
MESH:D010190 Pancreatic Neoplasms Tretinoin 9.6415976015
MESH:D010195 Pancreatitis orlistat 4.1916938137 20065556
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.0111578682
MESH:D010291 Paresis Thalidomide 5.569200351
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.5112520081
MESH:D010538 Peritonitis Ozone 3.4316369182
MESH:D010900 Pituitary Diseases Diethylstilbestrol 4.4314722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 3.9616977796 15687265
MESH:D011014 Pneumonia Ozone 3.6718929643 18007984 18381685
MESH:D011041 Poisoning Mustard Gas 3.1415727166
MESH:D011085 Polycystic Ovary Syndrome orlistat 4.6317201808
MESH:D011141 Polyuria Furosemide 4.9217945291
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 2.8718163543
MESH:D011230 Precancerous Conditions Cyclosporine 6.8712371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 6.872563599
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Cyclophosphamide 6.5321297632
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Thalidomide 6.5317031469
MESH:D011225 Pre-Eclampsia Zinc 3.5917114810
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 17.3617184923
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 17.3616679765
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 17.3611118676 11222880 11896295 11399792
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 17.3618042343 18220299 19015723
MESH:D011469 Prostatic Diseases vinclozolin 4.2118220299
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.2220887781
MESH:D011471 Prostatic Neoplasms Azacitidine 4.2618324645
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 4.2617292933
MESH:D011471 Prostatic Neoplasms Copper 4.2617308104 17079463
MESH:D011471 Prostatic Neoplasms Curcumin 4.2610851300 18769126 11398177 15129424 18226269 12497104 18156803
MESH:D011471 Prostatic Neoplasms Cyclophosphamide 4.2617136230
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 4.2615046698 17136230 15846301
MESH:D011471 Prostatic Neoplasms Estradiol 4.2616740699
MESH:D011471 Prostatic Neoplasms gefitinib 4.2617914592 15651060 16685379
MESH:D011471 Prostatic Neoplasms resveratrol 4.2615767336 17804756 17718901 17636462 16731767 17675339
MESH:D011471 Prostatic Neoplasms Thalidomide 4.2616729912
MESH:D011471 Prostatic Neoplasms Thiram 4.2619789329
MESH:D011471 Prostatic Neoplasms Zinc 4.2616700911 16517595 16606632 12429649
MESH:D011472 Prostatitis vinclozolin 4.2118629315
MESH:D011507 Proteinuria Tretinoin 7.3616636307
MESH:D011507 Proteinuria valsartan 7.3617664856 12164870 18344623
MESH:D011536 Prurigo Thalidomide 5.5612755975
MESH:D011537 Pruritus Ethinyl Estradiol 7.1316919318 15861022
MESH:D011537 Pruritus Mustard Gas 7.1318058305
MESH:D011565 Psoriasis Cyclosporine 1.9216882103
MESH:D011625 Pterygium Tretinoin 4.0616723453
MESH:D011656 Pulmonary Emphysema Curcumin 3.8819168576
MESH:D011658 Pulmonary Fibrosis Amiodarone 13.7612490602 12832656 11597910
MESH:D011658 Pulmonary Fibrosis Cyclophosphamide 13.7616636934
MESH:D011658 Pulmonary Fibrosis gefitinib 13.7618424623
MESH:D011658 Pulmonary Fibrosis Mustard Gas 13.7617720292 17266442 17620002 17894541 10334151
MESH:D011658 Pulmonary Fibrosis valsartan 13.7617241526
MESH:D012035 Refsum Disease orlistat 5.3420871815
MESH:D051436 Renal Insufficiency, Chronic resveratrol 4.8416325855
MESH:D015427 Reperfusion Injury marker/mechanism 16526316
MESH:D015427 Reperfusion Injury Furosemide 8.6316526316
MESH:D015427 Reperfusion Injury pirinixic acid 8.6319058328
MESH:D015427 Reperfusion Injury resveratrol 8.6315827377 16314181 16317513 17520802 17058453
MESH:D012128 Respiratory Distress Syndrome, Adult Acetylcysteine 11.5412210543
MESH:D012128 Respiratory Distress Syndrome, Adult Curcumin 11.5418379247 10666014
MESH:D012128 Respiratory Distress Syndrome, Adult Furosemide 11.5415912074 12394941 16096441
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.1418990726
MESH:D012162 Retinal Degeneration Zinc 3.5616584753
MESH:D012208 Rhabdomyosarcoma Tretinoin 3.4216283617 16116481
MESH:D012509 Sarcoma Curcumin 3.4818462866
MESH:D012559 Schizophrenia Copper 2.9716842975
MESH:D019873 Schnitzler Syndrome Thalidomide 5.2116096327
MESH:D012595 Scleroderma, Systemic Cyclophosphamide 4.1516636934
MESH:D012640 Seizures 2,4-dinitrotoluene 4.1518551238
MESH:D012640 Seizures 2,6-dinitrotoluene 4.1518551238
MESH:D018805 Sepsis Curcumin 3.4718389075
OMIM:609620 SHORT QT SYNDROME 1 Amiodarone 4.3618724381
MESH:D012852 Sinusitis Phenylephrine 3.987327846
MESH:D012871 Skin Diseases Mustard Gas 2.4812880345 16961503 15451306
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 13.6510029692 19755658
MESH:D012878 Skin Neoplasms deguelin 13.6516041863
MESH:D012878 Skin Neoplasms resveratrol 13.6515837718 8985016
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 13.6516192470
MESH:D012878 Skin Neoplasms Tretinoin 13.6516467112
MESH:D013088 Spermatocele Diethylstilbestrol 9.2616709447 16002989
MESH:D013088 Spermatocele Ethinyl Estradiol 9.2616709447
OMIM:102530 SPERMATOGENIC FAILURE 6 Cyclophosphamide 4.7916517039
MESH:D013272 Stomach Diseases Omeprazole 3.8918545984
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 5.212093021 20155912
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 5.2118456281
MESH:D013274 Stomach Neoplasms Furosemide 5.2117052386
MESH:D013274 Stomach Neoplasms orlistat 5.2119381703
MESH:D013274 Stomach Neoplasms Tretinoin 5.2117261132
MESH:D013276 Stomach Ulcer Acetylcysteine 15.7417918041
MESH:D013276 Stomach Ulcer Amiodarone 15.7418087811
MESH:D013276 Stomach Ulcer Curcumin 15.7416631530 19188055
MESH:D013276 Stomach Ulcer Omeprazole 15.7417977527 18237397 15991576 10750652 11906479 16755016
MESH:D013276 Stomach Ulcer Thalidomide 15.7415138204
OMIM:601367 STROKE, ISCHEMIC resveratrol 3.8416321402
MESH:D015173 Supratentorial Neoplasms Cyclophosphamide 4.3312837982
MESH:D013610 Tachycardia Amiodarone 3.6011238279
MESH:D017180 Tachycardia, Ventricular Amiodarone 3.5019225199
MESH:D019851 Thrombophilia Ethinyl Estradiol 2.9411994571
MESH:D013927 Thrombosis Ethinyl Estradiol 7.5315669648
MESH:D013927 Thrombosis SU 5416 7.5312649163
MESH:D013959 Thyroid Diseases Amiodarone 9.5919731979
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 9.5912697716
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 16.487505956
MESH:D013964 Thyroid Neoplasms gefitinib 16.4816940797
MESH:D013964 Thyroid Neoplasms N-(4-bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine 16.4816940797
MESH:D013964 Thyroid Neoplasms Propylthiouracil 16.4815710170
MESH:D013964 Thyroid Neoplasms Tretinoin 16.4816026305 17045167
MESH:D013971 Thyrotoxicosis Amiodarone 4.1518020914 19584973
MESH:D013978 Tibial Fractures Estradiol 3.9419048282
MESH:D014062 Tongue Neoplasms resveratrol 12.9416227395
MESH:D014062 Tongue Neoplasms Tretinoin 12.9416051514
MESH:D014062 Tongue Neoplasms Zinc 12.9416543248
MESH:D016171 Torsades de Pointes Amiodarone 3.4717467628 11989578
MESH:D014376 Tuberculosis Tretinoin 2.7316040207
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 15.2816049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 15.2816049721
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 15.2817053015
MESH:D001749 Urinary Bladder Neoplasms Curcumin 15.2818593936
MESH:D001749 Urinary Bladder Neoplasms Cyclophosphamide 15.2814692829
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 15.2817306315 16452187 16712894
MESH:D014565 Urogenital Neoplasms Curcumin 4.5418462866
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 9.5810091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 9.5810091137
MESH:D014581 Urticaria Acetaminophen 2.3110982225
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 12.2316175088
MESH:D002583 Uterine Cervical Neoplasms resveratrol 12.2317473185
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 12.2316129372
MESH:D014591 Uterine Diseases Diethylstilbestrol 4.4314652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 12.0915809267 16690809
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 12.0914692618
MESH:D014594 Uterine Neoplasms resveratrol 12.0917044934
MESH:D014604 Uveal Neoplasms Tretinoin 3.8716752155
MESH:D014605 Uveitis Cyclosporine 3.241336536
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 3.7316513791 16002989
MESH:D014652 Vascular Diseases Thalidomide 4.7615741222
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 3.8512125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 2.8814671159 15869587
MESH:D018487 Ventricular Dysfunction, Left resveratrol 3.6017488730
MESH:D020257 Ventricular Remodeling valsartan 4.9719027736
MESH:D014820 Vitiligo Tretinoin 3.3616761959
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.5115886252
MESH:D015430 Weight Gain Dietary Fats 3.1116723640
MESH:D009396 Wilms Tumor Tretinoin 3.3416287080
MESH:D014947 Wounds and Injuries sphingosine 1-phosphate 4.8615541073
MESH:D014985 Xerophthalmia Cyclosporine 3.7017120751
Pathway ID Pathway Name
KEGG:04060 Cytokine-cytokine receptor interaction
KEGG:04144 Endocytosis
KEGG:04510 Focal adhesion
REACT:12529 Signaling by VEGF
KEGG:04370 VEGF signaling pathway
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA30086
    • No data
    Releated disease ID Related disease Name
    PA444985Multiple Myeloma
    PA443265Adenocarcinoma
    PA445062Neoplasms
    PA134850558Macular Degeneration
    PA443448Asthenia
    PA443560Breast Neoplasms
    PA443624Carcinoma, Renal Cell
    PA443899Diarrhea
    PA443937Drug Toxicity
    PA444153Fatigue
    PA151958383Gastrointestinal Stromal Tumors
    PA444552Hypertension
    PA445113Neutropenia
    PA152132901Hereditary Breast/Ovarian Cancer Syndrome
    PA445204Ovarian Neoplasms
    Releated drug ID Related drug Name
    PA164924493axitinib
    PA162372840sunitinib
    PA164924492brivanib
    PA130232992bevacizumab
    PA448478l-arginine
    PA450635nitric oxide
    PA7000sorafenib
    PA7001vatalanib
    PA451365sirolimus
    PA165291474BSI-201
    PA164920420Olaparib
    PA165291492pazopanib
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB00398 antagonist Sorafenib Antineoplastic Agents;Protein Kinase Inhibitors;Anticancer Agents
    DB01268 multitarget Sunitinib Antineoplastic Agents;Angiogenesis Inhibitors
    DB04727 - N-(4-{4-AMINO-6-[4-(METHYLOXY)PHENYL]FURO[2,3-D]PYRIMIDIN-5-YL}PHENYL)-N'-[2-FLUORO-5-(TRIFLUOROMETHYL)PHENYL]UREA
    DB06938 - 4-[[2-[[4-chloro-3-(trifluoromethyl)phenyl]amino]-3H-benzimidazol-5-yl]oxy]-N-methyl-pyridine-2-carboxamide
    DB07183 - N-(4-phenoxyphenyl)-2-[(pyridin-4-ylmethyl)amino]nicotinamide
    DB07274 - N-cyclopropyl-6-[(6,7-dimethoxyquinolin-4-yl)oxy]naphthalene-1-carboxamide
    DB07326 - 6-chloro-N-pyrimidin-5-yl-3-{[3-(trifluoromethyl)phenyl]amino}-1,2-benzisoxazole-7-carboxamide
    DB07333 - N-(CYCLOPROPYLMETHYL)-4-(METHYLOXY)-3-({5-[3-(3-PYRIDINYL)PHENYL]-1,3-OXAZOL-2-YL}AMINO)BENZENESULFONAMIDE
    DB07334 - N-[5-(ETHYLSULFONYL)-2-METHOXYPHENYL]-5-[3-(2-PYRIDINYL)PHENYL]-1,3-OXAZOL-2-AMINE
    DB07514 - 3-(2-aminoquinazolin-6-yl)-1-(3,3-dimethylindolin-6-yl)-4-methylpyridin-2(1H)-one
    DB07528 - 3-(2-aminoquinazolin-6-yl)-4-methyl-1-[3-(trifluoromethyl)phenyl]pyridin-2(1H)-one
    DB07537 - N'-(6-aminopyridin-3-yl)-N-(2-cyclopentylethyl)-4-methyl-benzene-1,3-dicarboxamide
    DB08042 - N~4~-methyl-N~4~-(3-methyl-1H-indazol-6-yl)-N~2~-(3,4,5-trimethoxyphenyl)pyrimidine-2,4-diamine
    DB08519 - N~4~-(3-methyl-1H-indazol-6-yl)-N~2~-(3,4,5-trimethoxyphenyl)pyrimidine-2,4-diamine
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


    Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved