Annotation Detail for KIF5A

Basic Information
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Desease ID | Desease Name |
---|
1792 | Spastic paraplegia, Hereditary |
Desease Name |
---|
Rheumatoid arthritis |
Desease Name |
---|
Spastic paraplegia 10 |
Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
---|
D002330 |
Carmustine |
Carmustine results in decreased expression of KIF5A mRNA | decreases expression | 15980968
|
D016047 |
Zalcitabine |
[gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of KIF5A mRNA | affects cotreatment|decreases expression | 18606552
|
D004052 |
Diethylnitrosamine |
Diethylnitrosamine results in increased expression of KIF5A mRNA | increases expression | 17854601
|
D004052 |
Diethylnitrosamine |
RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of KIF5A mRNA] | decreases reaction|increases expression | 17854601
|
C514793 |
gp120 protein, Human immunodeficiency virus 1 |
[gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of KIF5A mRNA | affects cotreatment|decreases expression | 18606552
|
C025643 |
vinclozolin |
vinclozolin affects the expression of KIF5A mRNA | affects expression | 19015723
|
Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
---|
MESH:D000236 |
Adenoma |
|
Diethylnitrosamine |
3.03 | 6695378 10737359 |
MESH:D018248 |
Adenoma, Liver Cell |
|
Diethylnitrosamine |
4.44 | 16434500 17620307 17162532 19061943 18056438 19052882 |
MESH:D001008 |
Anxiety Disorders |
|
vinclozolin |
3.93 | 19015723 |
MESH:D001932 |
Brain Neoplasms |
|
Carmustine |
4.73 | 16187019 |
MESH:D001943 |
Breast Neoplasms |
|
Diethylnitrosamine |
2.19 | 17474063 |
MESH:D006528 |
Carcinoma, Hepatocellular |
|
Diethylnitrosamine |
1.87 | 20727157 20084675 18393292 16698587 19539802 19822196 20514400 19107877 17978847 19383236 18506893 16540662 16878318 11831363 19919837 20935162 3084413 21159647 18788625 17162532 10672840 16830150 16569478 18785209 16681979 18494052 20214788 17138121 19701751 17428255 16328049 16779866 16288022 18978308 20432363 16807293 17173139 20512989 16935385 20007298 18691550 20101231 17055752 19519916 19208518 20524982 18056438 19335982 19052882 19394651 16502159 3581430 18210153 19171122 17761372 18665156 19418558 10737359 18971187 |
MESH:D009202 |
Cardiomyopathies |
|
Zalcitabine |
4.92 | 10591146 |
MESH:D002471 |
Cell Transformation, Neoplastic |
|
Diethylnitrosamine |
3.09 | 17174075 2727394 7505956 21159647 |
MESH:D018281 |
Cholangiocarcinoma |
|
Diethylnitrosamine |
4.01 | 19052882 |
MESH:D003456 |
Cryptorchidism |
|
vinclozolin |
4.78 | 14966744 |
MESH:D003924 |
Diabetes Mellitus, Type 2 |
|
Diethylnitrosamine |
2.25 | 20387270 |
MESH:D056486 |
Drug-Induced Liver Injury |
|
Diethylnitrosamine |
2.13 | 19107877 |
MESH:D004362 |
Drug Toxicity |
|
Zalcitabine |
5.11 | 7515130 |
MESH:D004931 |
Esophageal Achalasia |
|
Diethylnitrosamine |
5.73 | 16302075 |
MESH:D005234 |
Fatty Liver |
|
Diethylnitrosamine |
9.68 | 20387270 21071580 |
MESH:D005234 |
Fatty Liver |
|
Zalcitabine |
9.68 | 18299183 |
MESH:D030342 |
Genetic Diseases, Inborn |
|
vinclozolin |
5.47 | 16973722 |
MESH:D005832 |
Genital Diseases, Male |
|
vinclozolin |
5.91 | 16417039 |
MESH:D005909 |
Glioblastoma |
|
Carmustine |
4.14 | 16187019 |
MESH:D015658 |
HIV Infections |
|
Zalcitabine |
4.49 | 17457083 |
MESH:D007248 |
Infertility, Male |
|
vinclozolin |
3.26 | 16467254 |
MESH:D007249 |
Inflammation |
|
Diethylnitrosamine |
2.53 | 18785209 |
MESH:D007984 |
Leydig Cell Tumor |
|
vinclozolin |
5.27 | 16417039 |
MESH:D008103 |
Liver Cirrhosis |
|
Diethylnitrosamine |
2.99 | 18665156 18407596 18522880 19638242 20032147 |
MESH:D008107 |
Liver Diseases |
|
Diethylnitrosamine |
2.16 | 17034775 |
MESH:D008113 |
Liver Neoplasms |
|
Diethylnitrosamine |
2.34 | 19426721 19690152 18754104 20583210 19499222 19256749 20452335 16942905 19254457 19427195 19294768 19833225 20501860 9163691 20101389 20434301 19812893 19996281 19638242 19850985 20118626 21047994 15175105 21167192 12112319 15885732 18644402 19073162 21278145 20492335 18648771 10737359 20137499 19255062 18977376 20405173 18978307 2862719 12771043 19090486 19642983 21071580 2422723 19551842 |
MESH:D008114 |
Liver Neoplasms, Experimental |
|
Diethylnitrosamine |
2.83 | 18544905 2563599 19539802 17174075 16267830 9362446 18079962 17942915 19009564 18093689 18775883 19126423 19004024 21159647 19519916 17854601 3124819 18308698 18164116 16842330 18282651 18253720 |
MESH:D008175 |
Lung Neoplasms |
|
Diethylnitrosamine |
1.76 | 20512841 20970405 21163286 6695378 |
MESH:D008223 |
Lymphoma |
|
Zalcitabine |
4.88 | 9488045 11980663 17941976 18798262 8764131 9205081 8840982 |
MESH:D008545 |
Melanoma |
|
Carmustine |
2.90 | 12393984 |
MESH:D009362 |
Neoplasm Metastasis |
|
Diethylnitrosamine |
2.68 | 3581430 9029167 |
MESH:D009374 |
Neoplasms, Experimental |
|
Zalcitabine |
5.58 | 8764131 9488045 9205081 |
MESH:D009437 |
Neuralgia |
|
Zalcitabine |
6.86 | 17292584 |
MESH:D019636 |
Neurodegenerative Diseases |
|
Diethylnitrosamine |
3.65 | 20387270 |
MESH:D009461 |
Neurologic Manifestations |
|
Diethylnitrosamine |
5.73 | 20387270 |
MESH:D010190 |
Pancreatic Neoplasms |
|
Diethylnitrosamine |
2.52 | 16540662 |
MESH:D010523 |
Peripheral Nervous System Diseases |
|
gp120 protein, Human immunodeficiency virus 1 |
12.44 | 18606552 |
MESH:D010523 |
Peripheral Nervous System Diseases |
|
Zalcitabine |
12.44 | 18606552 |
MESH:D011230 |
Precancerous Conditions |
|
Diethylnitrosamine |
3.88 | 2563599 |
MESH:D011297 |
Prenatal Exposure Delayed Effects |
|
vinclozolin |
4.44 | 18042343 18220299 19015723 |
MESH:D011469 |
Prostatic Diseases |
|
vinclozolin |
5.47 | 18220299 |
MESH:D011472 |
Prostatitis |
|
vinclozolin |
5.47 | 18629315 |
MESH:C537482 |
Spastic paraplegia 10, autosomal dominant |
marker/mechanism |
|
| |
MESH:D013274 |
Stomach Neoplasms |
|
Diethylnitrosamine |
1.76 | 18456281 |
MESH:D013964 |
Thyroid Neoplasms |
|
Diethylnitrosamine |
3.25 | 7505956 |
PharmGKB Accession:PA30107
Releated disease ID |
Related disease Name |
PA443434 | Arthritis, Rheumatoid |
PA443434 | Arthritis, Rheumatoid |