Gene Symbol:	KIF5A ( D12S1889,MY050,NKHC,SPG10 )
Gene Full Name:	kinesin family member 5A
Band:	12q13.3
Quick Links	Entrez ID:3798; OMIM: 602821; Uniprot ID:KIF5A_HUMAN; ENSEMBL ID: ENSG00000155980; HGNC ID: 6323
Relate to Another Database:	SFARIGene; denovo-db

Chemical ID	Chemical Name	Interaction	Interaction Action	Publication
D002330	Carmustine	Carmustine results in decreased expression of KIF5A mRNA	decreases expression	15980968
D016047	Zalcitabine	[gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of KIF5A mRNA	affects cotreatment\|decreases expression	18606552
D004052	Diethylnitrosamine	Diethylnitrosamine results in increased expression of KIF5A mRNA	increases expression	17854601
D004052	Diethylnitrosamine	RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of KIF5A mRNA]	decreases reaction\|increases expression	17854601
C514793	gp120 protein, Human immunodeficiency virus 1	[gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of KIF5A mRNA	affects cotreatment\|decreases expression	18606552
C025643	vinclozolin	vinclozolin affects the expression of KIF5A mRNA	affects expression	19015723

Disease ID	Disease Name	Direct Evidence	Inference Chemical Name	Inference Score	Publication
MESH:D000236	Adenoma		Diethylnitrosamine	3.03	6695378 10737359
MESH:D018248	Adenoma, Liver Cell		Diethylnitrosamine	4.44	16434500 17620307 17162532 19061943 18056438 19052882
MESH:D001008	Anxiety Disorders		vinclozolin	3.93	19015723
MESH:D001932	Brain Neoplasms		Carmustine	4.73	16187019
MESH:D001943	Breast Neoplasms		Diethylnitrosamine	2.19	17474063
MESH:D006528	Carcinoma, Hepatocellular		Diethylnitrosamine	1.87	20727157 20084675 18393292 16698587 19539802 19822196 20514400 19107877 17978847 19383236 18506893 16540662 16878318 11831363 19919837 20935162 3084413 21159647 18788625 17162532 10672840 16830150 16569478 18785209 16681979 18494052 20214788 17138121 19701751 17428255 16328049 16779866 16288022 18978308 20432363 16807293 17173139 20512989 16935385 20007298 18691550 20101231 17055752 19519916 19208518 20524982 18056438 19335982 19052882 19394651 16502159 3581430 18210153 19171122 17761372 18665156 19418558 10737359 18971187
MESH:D009202	Cardiomyopathies		Zalcitabine	4.92	10591146
MESH:D002471	Cell Transformation, Neoplastic		Diethylnitrosamine	3.09	17174075 2727394 7505956 21159647
MESH:D018281	Cholangiocarcinoma		Diethylnitrosamine	4.01	19052882
MESH:D003456	Cryptorchidism		vinclozolin	4.78	14966744
MESH:D003924	Diabetes Mellitus, Type 2		Diethylnitrosamine	2.25	20387270
MESH:D056486	Drug-Induced Liver Injury		Diethylnitrosamine	2.13	19107877
MESH:D004362	Drug Toxicity		Zalcitabine	5.11	7515130
MESH:D004931	Esophageal Achalasia		Diethylnitrosamine	5.73	16302075
MESH:D005234	Fatty Liver		Diethylnitrosamine	9.68	20387270 21071580
MESH:D005234	Fatty Liver		Zalcitabine	9.68	18299183
MESH:D030342	Genetic Diseases, Inborn		vinclozolin	5.47	16973722
MESH:D005832	Genital Diseases, Male		vinclozolin	5.91	16417039
MESH:D005909	Glioblastoma		Carmustine	4.14	16187019
MESH:D015658	HIV Infections		Zalcitabine	4.49	17457083
MESH:D007248	Infertility, Male		vinclozolin	3.26	16467254
MESH:D007249	Inflammation		Diethylnitrosamine	2.53	18785209
MESH:D007984	Leydig Cell Tumor		vinclozolin	5.27	16417039
MESH:D008103	Liver Cirrhosis		Diethylnitrosamine	2.99	18665156 18407596 18522880 19638242 20032147
MESH:D008107	Liver Diseases		Diethylnitrosamine	2.16	17034775
MESH:D008113	Liver Neoplasms		Diethylnitrosamine	2.34	19426721 19690152 18754104 20583210 19499222 19256749 20452335 16942905 19254457 19427195 19294768 19833225 20501860 9163691 20101389 20434301 19812893 19996281 19638242 19850985 20118626 21047994 15175105 21167192 12112319 15885732 18644402 19073162 21278145 20492335 18648771 10737359 20137499 19255062 18977376 20405173 18978307 2862719 12771043 19090486 19642983 21071580 2422723 19551842
MESH:D008114	Liver Neoplasms, Experimental		Diethylnitrosamine	2.83	18544905 2563599 19539802 17174075 16267830 9362446 18079962 17942915 19009564 18093689 18775883 19126423 19004024 21159647 19519916 17854601 3124819 18308698 18164116 16842330 18282651 18253720
MESH:D008175	Lung Neoplasms		Diethylnitrosamine	1.76	20512841 20970405 21163286 6695378
MESH:D008223	Lymphoma		Zalcitabine	4.88	9488045 11980663 17941976 18798262 8764131 9205081 8840982
MESH:D008545	Melanoma		Carmustine	2.90	12393984
MESH:D009362	Neoplasm Metastasis		Diethylnitrosamine	2.68	3581430 9029167
MESH:D009374	Neoplasms, Experimental		Zalcitabine	5.58	8764131 9488045 9205081
MESH:D009437	Neuralgia		Zalcitabine	6.86	17292584
MESH:D019636	Neurodegenerative Diseases		Diethylnitrosamine	3.65	20387270
MESH:D009461	Neurologic Manifestations		Diethylnitrosamine	5.73	20387270
MESH:D010190	Pancreatic Neoplasms		Diethylnitrosamine	2.52	16540662
MESH:D010523	Peripheral Nervous System Diseases		gp120 protein, Human immunodeficiency virus 1	12.44	18606552
MESH:D010523	Peripheral Nervous System Diseases		Zalcitabine	12.44	18606552
MESH:D011230	Precancerous Conditions		Diethylnitrosamine	3.88	2563599
MESH:D011297	Prenatal Exposure Delayed Effects		vinclozolin	4.44	18042343 18220299 19015723
MESH:D011469	Prostatic Diseases		vinclozolin	5.47	18220299
MESH:D011472	Prostatitis		vinclozolin	5.47	18629315
MESH:C537482	Spastic paraplegia 10, autosomal dominant	marker/mechanism
MESH:D013274	Stomach Neoplasms		Diethylnitrosamine	1.76	18456281
MESH:D013964	Thyroid Neoplasms		Diethylnitrosamine	3.25	7505956

Releated disease ID	Related disease Name
PA443434	Arthritis, Rheumatoid
PA443434	Arthritis, Rheumatoid

AutismKB 2.0

Annotation Detail for KIF5A

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