AutismKB 2.0

Annotation Detail for KIF11


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Basic Information Top
Gene Symbol:KIF11 ( EG5,HKSP,KNSL1,TRIP5 )
Gene Full Name: kinesin family member 11
Band: 10q23.33
Quick LinksEntrez ID:3832; OMIM: 148760; Uniprot ID:KIF11_HUMAN; ENSEMBL ID: ENSG00000138160; HGNC ID: 6388
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1904Diabetes mellitus
1934Cancer
Desease Name
METABOLIC
diabetes, type 2
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C404910 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the expression of KIF11 mRNAaffects expression 19414516
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane affects the expression of KIF11 mRNAaffects expression 18648102
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of KIF11 proteinaffects expression 20106945
D000643 Ammonium Chloride Ammonium Chloride affects the expression of KIF11 mRNAaffects expression 16483693
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of KIF11 mRNAdecreases expression 20064835
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of KIF11 mRNAdecreases expression 20382639
19150397
C006780 bisphenol A bisphenol A results in increased expression of KIF11 mRNAincreases expression 16474171
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of KIF11 mRNAaffects expression 17484886
D016572 Cyclosporine Cyclosporine results in decreased expression of KIF11 mRNAdecreases expression 20106945
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of KIF11 mRNAincreases expression 17854601
D004052 Diethylnitrosamine RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of KIF11 mRNA]decreases reaction|increases expression 17854601
D004958 Estradiol Estradiol results in increased expression of KIF11 mRNAincreases expression 16474171
20106945
D019833 Genistein Genistein results in increased expression of KIF11 mRNAincreases expression 16474171
D008748 Methylcholanthrene Methylcholanthrene results in increased expression of KIF11 mRNAincreases expression 20713471
C008493 methylselenic acid methylselenic acid results in decreased expression of KIF11 mRNAdecreases expression 12517777
D011078 Polychlorinated Biphenyls Polychlorinated Biphenyls analog results in increased expression of KIF11 mRNAincreases expression 16474171
C059514 resveratrol resveratrol results in decreased expression of KIF11 mRNAdecreases expression 15767336
C410733 scriptaid scriptaid affects the expression of KIF11 mRNAaffects expression 18813790
C017947 sodium arsenite sodium arsenite results in decreased expression of KIF11 mRNAdecreases expression 17998272
C496197 trans-10,cis-12-conjugated linoleic acid trans-10,cis-12-conjugated linoleic acid results in decreased expression of KIF11 mRNAdecreases expression 17951470
D014747 Vinblastine KIF11 protein affects the susceptibility to Vinblastineaffects response to substance 16217747
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 3.4718287403
MESH:D058186 Acute Kidney Injury resveratrol 3.7716538975
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 6.9620464547 20127859
MESH:D000230 Adenocarcinoma Estradiol 6.9611473722
MESH:D000230 Adenocarcinoma Genistein 6.9611473722
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 20.493712494
MESH:D000236 Adenoma Benzo(a)pyrene 20.496695378
MESH:D000236 Adenoma Diethylnitrosamine 20.4910737359 6695378
MESH:D000236 Adenoma Methylcholanthrene 20.4910545420 6695378
MESH:D000236 Adenoma resveratrol 20.4915688382
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 3.8219052882 17162532 17620307 16434500 19061943 18056438
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.6215276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.8217306315 16712894
MESH:D000544 Alzheimer Disease resveratrol 2.5516183991 16162502
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.9919183758
MESH:D001169 Arthritis, Experimental resveratrol 3.4517115116
MESH:D050197 Atherosclerosis Methylcholanthrene 6.7911922910
MESH:D050197 Atherosclerosis resveratrol 6.7917967414 16873680
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.9411289319 1440618
MESH:D001862 Bone Resorption bisphenol A 3.7811985600
MESH:D002545 Brain Ischemia resveratrol 4.2017600658
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 3.7220146248 17474063
MESH:D001943 Breast Neoplasms bisphenol A 3.7217123778
MESH:D001943 Breast Neoplasms Diethylnitrosamine 3.7217474063
MESH:D001943 Breast Neoplasms Estradiol 3.7217289903 18497071 12948864 19861407 17261762 14630087 17018787 16675129
MESH:D001943 Breast Neoplasms Genistein 3.7216873071 17200150 16541309
MESH:D001943 Breast Neoplasms Methylcholanthrene 3.7217474063
MESH:D001943 Breast Neoplasms resveratrol 3.7217651959 16393696 17534123
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.3816111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.6916097048 15673190 16192424 15721981 10355542 15700767 16124888 16227642 3786805 16050911 16011737 18705752
MESH:D002277 Carcinoma Methylcholanthrene 3.9010545420
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 16.713581430 7296757
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 16.7121507988 12907637 12619106
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 16.7118788625
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 16.7118691550 17978847 17173139 17162532 10737359 17055752 16681979 18506893 16540662 16502159 17428255 18494052 16830150 18393292 18665156 18788625 20935162 19208518 18056438 19701751 19418558 20101231 19822196 16935385 20524982 19383236 16288022 16569478 11831363 20727157 16779866 10672840 20007298 3084413 16698587 16878318 20432363 16328049 19519916 20514400 20084675 19052882 19394651 19107877 19335982 18210153 3581430 20214788 18971187 19919837 18785209 19171122 21159647 19539802 16807293 17138121 18978308 17761372 20512989
MESH:D006528 Carcinoma, Hepatocellular Estradiol 16.7116924424
MESH:D006528 Carcinoma, Hepatocellular Genistein 16.7116924424
MESH:D006528 Carcinoma, Hepatocellular resveratrol 16.7119321006 16227395
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 16.7115276417 17306315 16507464
MESH:D002278 Carcinoma in Situ bisphenol A 4.9017123778
MESH:D018827 Carcinoma, Lewis Lung resveratrol 4.5116675471
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 6.647296757
MESH:D002292 Carcinoma, Renal Cell Vinblastine 6.641485588
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 7.4220419170
MESH:D002294 Carcinoma, Squamous Cell resveratrol 7.4216227395
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 7.4218572023
MESH:D002318 Cardiovascular Diseases Genistein 7.3116332659
MESH:D002318 Cardiovascular Diseases resveratrol 7.3115458977
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 30.897505956
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 30.8920889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 30.8912371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 30.8917174075 2727394 21159647 7505956
MESH:D002471 Cell Transformation, Neoplastic Estradiol 30.8918566989
MESH:D002471 Cell Transformation, Neoplastic Methylcholanthrene 30.8916192471
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 30.8920056578 19524636
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 3.6119052882
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 7.669022650 19486331
MESH:D002779 Cholestasis Cyclosporine 7.6619486331
MESH:D003092 Colitis resveratrol 4.0416474422
MESH:D003110 Colonic Neoplasms Genistein 3.8817182828
MESH:D003110 Colonic Neoplasms resveratrol 3.8816338953
MESH:D015179 Colorectal Neoplasms Polychlorinated Biphenyls 3.6715531428
MESH:D015179 Colorectal Neoplasms resveratrol 3.6716550006
MESH:D015179 Colorectal Neoplasms Vinblastine 3.6718802399
MESH:D003327 Coronary Disease resveratrol 3.6916507316
MESH:D003704 Dementia Polychlorinated Biphenyls 4.6216140633
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.7211906362 12868966 8970840 18759878 11298694 8156756 14531868 2524372
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.412952479 3621924
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 3.6916873680
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 4.4520387270
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 4.4516647724
MESH:D003928 Diabetic Nephropathies Estradiol 8.7619279558
MESH:D003928 Diabetic Nephropathies resveratrol 8.7616286809
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 6.091440618 9328219 18289764 18692083 9022650 16192314 7440962 9653073 6679447 8291058 6482804 11289319 18648102
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 6.0915998439 21278145 11566570 15968718 3732212 10915739 10092053 7179309 7120509 17522070 3786805 9327722 19085960 2869522 6623471 4309450 6884620 16227642 15027814 7440962 16177239 19336974
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 6.0919107877
MESH:D004487 Edema resveratrol 3.298985016
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 3.9417872969
MESH:D004714 Endometrial Hyperplasia Genistein 4.5016402032
MESH:D016889 Endometrial Neoplasms Estradiol 7.3111473722 18566989 19148513
MESH:D016889 Endometrial Neoplasms Genistein 7.3111473722
MESH:D020345 Enterocolitis, Necrotizing resveratrol 4.7617923197
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 5.0416302075
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 7.053581430
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7.0520426865
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 7.0516530937
MESH:D005234 Fatty Liver Carbon Tetrachloride 12.6312631006 16239168 15959796 17595544 12795759 61145 16045604 19224547
MESH:D005234 Fatty Liver Cyclosporine 12.6319224547
MESH:D005234 Fatty Liver Diethylnitrosamine 12.6321071580 20387270
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.946705139
MESH:D005354 Fibrosarcoma Methylcholanthrene 4.8514633661 10962813
MESH:D005355 Fibrosis Carbon Tetrachloride 8.3818705752
MESH:D005355 Fibrosis Cyclosporine 8.3812639820 12168785
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.5916452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.138708960
MESH:D005909 Glioblastoma Genistein 3.2016598420
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 3.957505956
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 2.6120471113
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.3415720958
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 8.946705139
MESH:D006505 Hepatitis Carbon Tetrachloride 8.9419110552 19900420
MESH:D006558 Herpes Genitalis Estradiol 4.9515709030
MESH:D006561 Herpes Simplex resveratrol 4.0916876885
MESH:D006689 Hodgkin Disease sodium arsenite 7.4512676792
MESH:D006689 Hodgkin Disease Vinblastine 7.4518501091 18180244
MESH:D019584 Hot Flashes Estradiol 3.6717088409
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.4516899240
MESH:D006937 Hypercholesterolemia resveratrol 3.9217188708
MESH:D006949 Hyperlipidemias resveratrol 3.9416873680
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.8515034207
MESH:D006973 Hypertension Cyclosporine 2.0710903974
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.0015338365
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 4.2217488730
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 4.5617600658
MESH:D007248 Infertility, Male sodium arsenite 2.9315346721 12646999
MESH:D007249 Inflammation Diethylnitrosamine 5.1118785209
MESH:D007249 Inflammation resveratrol 5.1116366677
MESH:D007251 Influenza, Human resveratrol 4.4616624496
MESH:D007333 Insulin Resistance bisphenol A 7.2416393666
MESH:D007333 Insulin Resistance Estradiol 7.2416393666 16627594
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.949022650 8074119
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.3615604871
MESH:D007674 Kidney Diseases Cyclosporine 9.768314463 10903974 18776723
MESH:D007674 Kidney Diseases Estradiol 9.7615618244
MESH:D007674 Kidney Diseases sodium arsenite 9.7620008137
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 11.946582329
MESH:D007680 Kidney Neoplasms Cyclosporine 11.9412371664
MESH:D007680 Kidney Neoplasms Estradiol 11.9415610895
MESH:D007938 Leukemia Genistein 2.9817468513 18980019
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 3.5216087638
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 6.4516943688 21278145 11408273 17174718 16239168 16221502 11903743 17157831 17334410
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 6.4520032147 18407596 18665156 19638242 18522880
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.149327722 15034207
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 3.4816015684 16192424 17805973 18472094 15730626 18418968 17869086 12632512 15818738 15959796 15931870 11481614 12666154 12609069 12389079 15052691 17481882 15876570 15925388 12445421 18395914 20821823 16248980 17640975 17761835 12741479 15673190 16011737 18279442 17976157 12546737 18395095 12632514 15893842 14748882 18420326 14716496 12958196 18006644 14724832 18412020 16033810 16136751 15650968 12445418 17631135 12649538 17944888 12898905 13678700 18205269 18317297 18472332 17900296 18277467 18705752 17922224 15057751 15338365 16116963 16638106 17766677 18054572 14716833 15370692 18156304 18376398 17565644 17823541 18187930 18210741 18166357 17708605 15996030 14620537 16097048 17698563 18481824 17714472 18263696 17557913 12667390 14512876 17525996 18251166 18429990 12586293 15362042 10355542 16027843 18339082 15123356 17721639
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 3.4814716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Genistein 3.4817823541
MESH:D008107 Liver Diseases Carbon Tetrachloride 4.0015830285 15720792 16964402 17285989 16246199
MESH:D008107 Liver Diseases Diethylnitrosamine 4.0017034775
MESH:D017093 Liver Failure Carbon Tetrachloride 4.0815123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 3.6114706259 16899240
MESH:D008113 Liver Neoplasms Aflatoxin B1 17.562125692 18177683 9163691 15890375
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 17.5621137059 20195826
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 17.5619294768
MESH:D008113 Liver Neoplasms Diethylnitrosamine 17.5620434301 21278145 15885732 20101389 19850985 18754104 21167192 19812893 9163691 20137499 19996281 18977376 19833225 19638242 19551842 19294768 18978307 19499222 19256749 19254457 19427195 12771043 19255062 18644402 20583210 12112319 20118626 20452335 19073162 18648771 16942905 15175105 2422723 19690152 2862719 19426721 20405173 20501860 19642983 10737359 20492335 21071580 19090486 21047994
MESH:D008113 Liver Neoplasms resveratrol 17.5619812893 19073162 19321006 20405173
MESH:D008113 Liver Neoplasms sodium arsenite 17.5615276417 16712894
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 22.67598648 3712494 1399818 6587162
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 22.678603461
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 22.6715583823 12014681
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 22.6721159647 18253720 16267830 2563599 18775883 19126423 18544905 18093689 18079962 18282651 19539802 9362446 19009564 18164116 16842330 17942915 18308698 3124819 17854601 19519916 17174075 19004024
MESH:D008114 Liver Neoplasms, Experimental Methylcholanthrene 22.67598648 1399818
MESH:D008114 Liver Neoplasms, Experimental Polychlorinated Biphenyls 22.671423854
MESH:D008171 Lung Diseases sodium arsenite 3.1119095001
MESH:D008175 Lung Neoplasms Aflatoxin B1 6.4914755239
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 6.4920464547 20869020 18816296 20135361 18569708 6695378 17053015 20064080 18520028
MESH:D008175 Lung Neoplasms Diethylnitrosamine 6.4920970405 6695378 20512841 21163286
MESH:D008175 Lung Neoplasms Methylcholanthrene 6.4920970405 10545420 1399818 9230183 16271038 21163286 16337739 17909032 15390079 6695378 11893704 20512841 7750092
MESH:D008175 Lung Neoplasms sodium arsenite 6.4916712894 17077188 17306315 19931552 15276417
MESH:D016393 Lymphoma, B-Cell resveratrol 4.2117088997
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 3.8014749477
MESH:D015674 Mammary Neoplasms, Animal resveratrol 4.1615688416
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 9.7216891317 11807958 11408345 17203775
MESH:D008325 Mammary Neoplasms, Experimental Genistein 9.7214578162 12929590
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 9.7211606380 8985016
MESH:D020149 Manganese Poisoning Estradiol 4.4019453300
MESH:D008545 Melanoma resveratrol 5.2017992120
MESH:D008545 Melanoma sodium arsenite 5.2016487513 19082730
MESH:D008545 Melanoma Vinblastine 5.2016432458 12374674 16248763 18176117 15577323 15577320 17761969 18332650 18505091 16809738
MESH:D008659 Metabolic Diseases resveratrol 4.2917112576
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.7116801185
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.1216381670
MESH:D009101 Multiple Myeloma resveratrol 3.4016490592 16267019 17049120 14749477 17164350 17935668
MESH:D009134 Muscular Atrophy, Spinal resveratrol 4.7817962980
MESH:D009203 Myocardial Infarction Genistein 5.8817141266
MESH:D009203 Myocardial Infarction resveratrol 5.8817015251 16525036 16317513 17188708 17125593 16456233
MESH:D017202 Myocardial Ischemia resveratrol 3.9417015251 17125593
MESH:D015428 Myocardial Reperfusion Injury Estradiol 8.2816810080
MESH:D015428 Myocardial Reperfusion Injury Genistein 8.2817141266
MESH:D009205 Myocarditis resveratrol 4.6717322642
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 5.593581430
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 5.593581430 9029167
MESH:D009369 Neoplasms Benzo(a)pyrene 4.8811141357
MESH:D009369 Neoplasms sodium arsenite 4.8811559025
MESH:D009374 Neoplasms, Experimental resveratrol 8.948985016
MESH:D009374 Neoplasms, Experimental sodium arsenite 8.9420056578
MESH:D009389 Neovascularization, Pathologic Estradiol 3.6517289903
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.3617954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.2119348381 18481113
MESH:D009421 Nervous System Malformations bisphenol A 15.9711399458 16427766
MESH:D009421 Nervous System Malformations Estradiol 15.9716427766 11399458
MESH:D009421 Nervous System Malformations Genistein 15.9716427766
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 7.076679447
MESH:D009436 Neural Tube Defects sodium arsenite 7.0712854658
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 8.2820387270
MESH:D019636 Neurodegenerative Diseases resveratrol 8.2817652729
MESH:D020078 Neurogenic Inflammation resveratrol 4.3117929310
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 5.0420387270
MESH:D009503 Neutropenia Vinblastine 4.4917378895
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.344026338 6482804
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.943988306
MESH:D010024 Osteoporosis Genistein 3.2019401787
MESH:D015663 Osteoporosis, Postmenopausal Genistein 9.8716169203
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 9.8717513867
MESH:D010049 Ovarian Diseases bisphenol A 4.9011985600
MESH:D010051 Ovarian Neoplasms Estradiol 7.7519401270
MESH:D010051 Ovarian Neoplasms Genistein 7.7519005980
MESH:D010051 Ovarian Neoplasms sodium arsenite 7.7517306315 15276417
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 2.3916540662
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.407296757
MESH:D010300 Parkinson Disease Polychlorinated Biphenyls 3.3616702228
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.396228378
MESH:D011230 Precancerous Conditions Cyclosporine 8.6912371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 8.692563599
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 9.5910548101
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 9.5916679765
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 10.2820887781
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 10.2820887781
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.4517292933
MESH:D011471 Prostatic Neoplasms bisphenol A 2.4516740699
MESH:D011471 Prostatic Neoplasms Estradiol 2.4516740699
MESH:D011471 Prostatic Neoplasms Genistein 2.4515378649 16925846 15256057
MESH:D011471 Prostatic Neoplasms methylselenic acid 2.4516205645
MESH:D011471 Prostatic Neoplasms Polychlorinated Biphenyls 2.4515721890
MESH:D011471 Prostatic Neoplasms resveratrol 2.4516731767 17675339 17718901 17636462 15767336 17804756
MESH:D011471 Prostatic Neoplasms sodium arsenite 2.4516039940
MESH:D011565 Psoriasis Cyclosporine 2.2016882103
MESH:D011629 Puberty, Precocious bisphenol A 4.7010548101
MESH:D051436 Renal Insufficiency, Chronic resveratrol 5.5016325855
MESH:D015427 Reperfusion Injury resveratrol 3.2316314181 15827377 17520802 16317513 17058453
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.313692021
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 9.2910029692 19755658
MESH:D012878 Skin Neoplasms resveratrol 9.298985016 15837718
MESH:D012878 Skin Neoplasms sodium arsenite 9.2919524636 18572023
MESH:D016135 Spinal Dysraphism sodium arsenite 3.7312854658
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 2.3120155912 2093021
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 2.3118456281
OMIM:601367 STROKE, ISCHEMIC resveratrol 4.4016321402
MESH:D019966 Substance-Related Disorders bisphenol A 3.9016045194 16684133
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 6.897505956 6582329 3712494 6587162 1399818
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 6.897505956
MESH:D013978 Tibial Fractures Estradiol 4.6019048282
MESH:D014062 Tongue Neoplasms resveratrol 4.1316227395
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 8.098074119
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 8.0917053015
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 8.0916712894 11723127 17306315 16452187
MESH:D002583 Uterine Cervical Neoplasms resveratrol 9.3017473185
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 9.3011813266
MESH:D014591 Uterine Diseases bisphenol A 4.9314652134
MESH:D014594 Uterine Neoplasms resveratrol 4.0517044934
MESH:D014605 Uveitis Cyclosporine 3.901336536
MESH:D014625 Vaginal Neoplasms Vinblastine 4.9615577323
MESH:D014652 Vascular Diseases sodium arsenite 4.3417056641
MESH:D018487 Ventricular Dysfunction, Left resveratrol 4.2117488730
MESH:D014985 Xerophthalmia Cyclosporine 4.3617120751
Pathway ID Pathway Name
REACT:604 Hemostasis
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA30177
    • No data
    Releated disease ID Related disease Name
    PA443890Diabetes Mellitus, Type 2
    No data
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB03431 - Adenosine-5'-Diphosphate
    DB03996 - 3-[(5s)-1-Acetyl-3-(2-Chlorophenyl)-4,5-Dihydro-1h-Pyrazol-5-Yl]Phenol
    DB04331 - Monastrol
    DB07064 - (4R)-4-(3-HYDROXYPHENYL)-N,N,7,8-TETRAMETHYL-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXAMIDE
    DB08032 - N,N-DIETHYL-2-[(2-THIENYLCARBONYL)AMINO]-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDE
    DB08033 - (5R)-N,N-DIETHYL-5-METHYL-2-[(THIOPHEN-2-YLCARBONYL)AMINO]-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDE
    DB08037 - (2S)-4-(2,5-difluorophenyl)-N-[(3R,4S)-3-fluoro-1-methylpiperidin-4-yl]-2-(hydroxymethyl)-N-methyl-2-phenyl-2,5-dihydro-1H-pyrrole-1-carboxamide
    DB08198 - [(4R)-4-(3-HYDROXYPHENYL)-1,6-DIMETHYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDIN-5-YL](PHENYL)METHANONE
    DB08239 - (2S)-4-(2,5-DIFLUOROPHENYL)-N-METHYL-2-PHENYL-N-PIPERIDIN-4-YL-2,5-DIHYDRO-1H-PYRROLE-1-CARBOXAMIDE
    DB08244 - (1S)-1-CYCLOPROPYL-2-[(2S)-4-(2,5-DIFLUOROPHENYL)-2-PHENYL-2,5-DIHYDRO-1H-PYRROL-1-YL]-2-OXOETHANAMINE
    DB08246 - (2S)-4-(2,5-DIFLUOROPHENYL)-N,N-DIMETHYL-2-PHENYL-2,5-DIHYDRO-1H-PYRROLE-1-CARBOXAMIDE
    DB08250 - (5S)-5-(3-AMINOPROPYL)-3-(2,5-DIFLUOROPHENYL)-N-ETHYL-5-PHENYL-4,5-DIHYDRO-1H-PYRAZOLE-1-CARBOXAMIDE
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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