AutismKB 2.0

Annotation Detail for KRAS


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Basic Information Top
Gene Symbol:KRAS ( C-K-RAS,K-RAS2A,K-RAS2B,K-RAS4A,K-RAS4B,KI-RAS,KRAS1,KRAS2,NS,NS3,RASK2 )
Gene Full Name: v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
Band: 12p12.1
Quick LinksEntrez ID:3845; OMIM: 190070; Uniprot ID:RASK_HUMAN; ENSEMBL ID: ENSG00000133703; HGNC ID: 6407
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04914Progesterone-mediated oocyte maturation
hsa05160Hepatitis C
hsa04912GnRH signaling pathway
hsa04910Insulin signaling pathway
hsa04916Melanogenesis
hsa04012ErbB signaling pathway
hsa04010MAPK signaling pathway
hsa04720Long-term potentiation
hsa04360Axon guidance
hsa04650Natural killer cell mediated cytotoxicity
hsa04320Dorso-ventral axis formation
hsa04540Gap junction
hsa04730Long-term depression
hsa05219Bladder cancer
hsa04530Tight junction
hsa04722Neurotrophin signaling pathway
hsa04960Aldosterone-regulated sodium reabsorption
hsa05211Renal cell carcinoma
hsa05216Thyroid cancer
hsa05223Non-small cell lung cancer
hsa05221Acute myeloid leukemia
hsa05220Chronic myeloid leukemia
hsa04810Regulation of actin cytoskeleton
hsa05218Melanoma
hsa05212Pancreatic cancer
hsa05213Endometrial cancer
hsa05210Colorectal cancer
hsa05214Glioma
hsa05215Prostate cancer
hsa04062Chemokine signaling pathway
hsa04370VEGF signaling pathway
hsa05200Pathways in cancer
hsa04660T cell receptor signaling pathway
hsa04662B cell receptor signaling pathway
hsa04664Fc epsilon RI signaling pathway
Pathway IDPathway Name
Signalling by NGF
Axon guidance
Hemostasis
Signaling by EGFR
Signaling by Insulin receptor
Signaling by PDGF
No data
Pathway IDPathway Name
P00053T cell activation
P04398p53 pathway feedback loops 2
P00056VEGF signaling pathway
P00018EGF receptor signaling pathway
P00005Angiogenesis
P00052TGF-beta signaling pathway
P00048PI3 kinase pathway
P00047PDGF signaling pathway
P00021FGF signaling pathway
P00034Integrin signalling pathway
P00031Inflammation mediated by chemokine and cytokine signaling pathway
P04393Ras Pathway
No data
Related Diseases/Disorders Top
Desease IDDesease Name
Cancers of haematopoietic and lymphoid tissues
Cancers
Viral infections
Cancers of the digestive system
H00003Acute myeloid leukemia (AML)
H00030Cervical cancer
H00019Pancreatic cancer
H00018Gastric cancer
H00014Non-small cell lung cancer
H00016Oral cancer
H00010Multiple myeloma
Skin cancers
H00020Colorectal cancer
H00026Endometrial cancer
H00027Ovarian cancer
Head and neck cancers
H00032Thyroid cancer
Cancers of endocrine organs
Infections caused by dsDNA viruses
Cancers of the lung and pleura
H00040Squamous cell carcinoma
H00041Kaposi's sarcoma
H00046Cholangiocarcinoma
H00047Gallbladder cancer
H00048Hepatocellular carcinoma
Cancers of the breast and female genital organs
Desease IDDesease Name
1901Endometriosis
1932Pancreatitis
1934Cancer
1979Testicular dysfunction
2102Polycystic ovary syndrome
1912Penile disease
Desease Name
leukemia, myeloid
colorectal cancer
CANCER
Carcinoma, Squamous Cell
PHARMACOGENOMIC
esophageal cancer
breast cancer colorectal cancer stomach cancer
lung adenocarcinoma
decreased apoptosis.
colon cancer
lung cancer
pancreatic carcinoma
mucinous ovarian tumor
Mouth Neoplasms
vinyl chloride exposure
smoking
No data
Desease Name
Stomach cancer
Bladder cancer
Pancreatic carcinoma, somatic
Leukemia, acute myelogenous
Cardiofaciocutaneous syndrome
Breast cancer, somatic
Noonan syndrome 3
Lung cancer
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C031763 1,3-butadiene 1,3-butadiene results in increased mutagenesis of KRAS geneincreases mutagenesis 11397402
C060080 2,2-bis(bromomethyl)-1,3-propanediol 2,2-bis(bromomethyl)-1,3-propanediol results in increased mutagenesis of KRAS geneincreases mutagenesis 14713543
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of KRAS mRNAaffects expression 21346803
C036990 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline results in increased mutagenesis of KRAS geneincreases mutagenesis 18271921
C016583 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased mutagenesis of KRAS geneincreases mutagenesis 18271921
D000082 Acetaminophen Acetaminophen affects the expression of KRAS mRNAaffects expression 17562736
D000643 Ammonium Chloride Ammonium Chloride affects the expression of KRAS mRNAaffects expression 16483693
D001194 Asbestos Asbestos results in increased mutagenesis of KRAS geneincreases mutagenesis 12725029
D001554 Benzene KRAS gene polymorphism results in increased susceptibility to Benzeneincreases response to substance 12807761
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased mutagenesis of KRAS geneincreases mutagenesis 19658153
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of KRAS mRNAdecreases expression 20018196
19150397
C006780 bisphenol A bisphenol A results in decreased expression of KRAS mRNAdecreases expression 16474171
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of KRAS mRNAaffects expression 17484886
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of KRAS mRNAincreases expression 8847708
D002713 Chlorine [Ozone co-treated with Chlorine] results in decreased expression of KRAS mRNAaffects cotreatment|decreases expression 18636392
D002737 Chloroprene Chloroprene results in increased mutagenesis of KRAS geneincreases mutagenesis 10223196
11397402
D004396 Coloring Agents Coloring Agents results in increased mutagenesis of KRAS geneincreases mutagenesis 14520703
D003474 Curcumin Curcumin analog results in decreased expression of KRAS mRNAdecreases expression 17041101
D003474 Curcumin Curcumin results in decreased expression of KRAS mRNAdecreases expression 17041101
D003513 Cycloheximide Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of KRAS mRNA]decreases reaction|increases expression 11007951
D003687 Dehydroepiandrosterone Dehydroepiandrosterone results in increased mutagenesis of KRAS geneincreases mutagenesis 8603461
C012457 diisopropanolnitrosamine diisopropanolnitrosamine results in increased mutagenesis of KRAS geneincreases mutagenesis 18271921
D004128 Dimethylnitrosamine Dimethylnitrosamine affects the localization of KRAS proteinaffects localization 11884234
D004128 Dimethylnitrosamine Dimethylnitrosamine results in decreased expression of and affects the localization of KRAS proteinaffects localization|decreases expression 19555203
D004128 Dimethylnitrosamine Tetrachlorodibenzodioxin promotes the reaction [Dimethylnitrosamine affects the localization of KRAS protein]affects localization|increases reaction 11884234
D004128 Dimethylnitrosamine Tetrachlorodibenzodioxin promotes the reaction [Dimethylnitrosamine results in decreased expression of KRAS protein]decreases expression|increases reaction 19555203
D004958 Estradiol Estradiol results in decreased expression of KRAS mRNAdecreases expression 16474171
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of KRAS mRNAaffects cotreatment|increases expression 17942748
D005038 Ethylnitrosourea Ethylnitrosourea promotes the reaction [GATA6 protein binds to KRAS exon]affects binding|increases reaction 16271038
D005038 Ethylnitrosourea Ethylnitrosourea promotes the reaction [NFYA protein binds to KRAS exon]affects binding|increases reaction 16271038
D005038 Ethylnitrosourea Ethylnitrosourea results in increased mutagenesis of KRAS geneincreases mutagenesis 15790496
D005472 Fluorouracil Fluorouracil results in decreased expression of KRAS proteindecreases expression 15585135
16803524
D019833 Genistein Genistein results in decreased expression of KRAS mRNAdecreases expression 15256057
16474171
D006220 Haloperidol Haloperidol results in increased expression of KRAS mRNAincreases expression 15860345
D006918 Hydroxyurea Hydroxyurea results in decreased expression of KRAS mRNAdecreases expression 12929121
D015759 Ionomycin Methohexital inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased activity of KRAS protein]affects cotreatment|decreases reaction|increases activity 15263067
D015759 Ionomycin Pentobarbital inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased activity of KRAS protein]affects cotreatment|decreases reaction|increases activity 15263067
D015759 Ionomycin Secobarbital inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased activity of KRAS protein]affects cotreatment|decreases reaction|increases activity 15263067
D015759 Ionomycin Thiamylal inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased activity of KRAS protein]affects cotreatment|decreases reaction|increases activity 15263067
C005059 isoprene isoprene results in increased mutagenesis of KRAS geneincreases mutagenesis 9111215
11397402
D008723 Methohexital Methohexital inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased activity of KRAS protein]affects cotreatment|decreases reaction|increases activity 15263067
D008748 Methylcholanthrene Methylcholanthrene promotes the reaction [GATA6 protein binds to KRAS exon]affects binding|increases reaction 16271038
D008748 Methylcholanthrene Methylcholanthrene promotes the reaction [NFYA protein binds to KRAS exon]affects binding|increases reaction 16271038
D008770 Methylnitrosourea Methylnitrosourea results in increased mutagenesis of KRAS geneincreases mutagenesis 12483526
18062963
D008770 Methylnitrosourea KRAS protein results in decreased susceptibility to Methylnitrosoureadecreases response to substance 11973638
D010126 Ozone [Ozone co-treated with Chlorine] results in decreased expression of KRAS mRNAaffects cotreatment|decreases expression 18636392
D010126 Ozone Ozone results in increased expression of KRAS mRNAincreases expression 16330353
D010424 Pentobarbital Pentobarbital inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased activity of KRAS protein]affects cotreatment|decreases reaction|increases activity 15263067
D010852 Picrotoxin Picrotoxin results in decreased expression of KRAS mRNAdecreases expression 15170462
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of KRAS mRNAaffects binding|increases activity|increases expression 19710929
D011078 Polychlorinated Biphenyls Polychlorinated Biphenyls analog results in decreased expression of KRAS mRNAdecreases expression 16474171
D011794 Quercetin Quercetin inhibits the reaction [KRAS protein affects the activity of TP53 protein]affects activity|decreases reaction 19424582
D011794 Quercetin Quercetin results in decreased expression of KRAS mRNAdecreases expression 10652438
D011794 Quercetin Quercetin results in decreased expression of KRAS proteindecreases expression 10652438
C052785 rebamipide rebamipide results in increased expression of KRAS mRNAincreases expression 18299717
C059514 resveratrol resveratrol results in decreased expression of KRAS mRNAdecreases expression 12569576
12002526
D012631 Secobarbital Secobarbital inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased activity of KRAS protein]affects cotreatment|decreases reaction|increases activity 15263067
C017947 sodium arsenite sodium arsenite affects the expression of KRAS mRNAaffects expression 16507464
C017947 sodium arsenite [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of KRAS mRNAaffects cotreatment|increases expression 16368122
C017947 sodium arsenite [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of KRAS proteinaffects cotreatment|increases expression 16368122
C017947 sodium arsenite sodium arsenite results in increased expression of KRAS mRNAincreases expression 16014739
C017947 sodium arsenite sodium arsenite results in increased expression of KRAS proteinincreases expression 16507464
C017947 sodium arsenite sodium arsenite results in increased expression of KRAS mRNAincreases expression 11241755
D020058 Styrene KRAS gene polymorphism results in increased susceptibility to Styreneincreases response to substance 12807761
D013467 Sulindac KRAS protein affects the susceptibility to Sulindacaffects response to substance 11751493
C004648 testosterone enanthate testosterone enanthate affects the expression of KRAS mRNAaffects expression 17440010
D013749 Tetrachlorodibenzodioxin Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of KRAS mRNA]decreases reaction|increases expression 11007951
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of KRAS mRNAincreases expression 20106945
11007951
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of KRAS mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin promotes the reaction [Dimethylnitrosamine affects the localization of KRAS protein]affects localization|increases reaction 11884234
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin promotes the reaction [Dimethylnitrosamine results in decreased expression of KRAS protein]decreases expression|increases reaction 19555203
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of KRAS mRNAdecreases expression 14708085
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of KRAS mRNAincreases expression 19465110
D013755 Tetradecanoylphorbol Acetate Methohexital inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased activity of KRAS protein]affects cotreatment|decreases reaction|increases activity 15263067
D013755 Tetradecanoylphorbol Acetate Pentobarbital inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased activity of KRAS protein]affects cotreatment|decreases reaction|increases activity 15263067
D013755 Tetradecanoylphorbol Acetate Secobarbital inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased activity of KRAS protein]affects cotreatment|decreases reaction|increases activity 15263067
D013755 Tetradecanoylphorbol Acetate Thiamylal inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased activity of KRAS protein]affects cotreatment|decreases reaction|increases activity 15263067
D013755 Tetradecanoylphorbol Acetate [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of KRAS mRNAaffects cotreatment|increases expression 16368122
D013755 Tetradecanoylphorbol Acetate [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of KRAS proteinaffects cotreatment|increases expression 16368122
D013774 Tetranitromethane Tetranitromethane results in increased mutagenesis of KRAS geneincreases mutagenesis 14713543
D013840 Thiamylal Thiamylal inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased activity of KRAS protein]affects cotreatment|decreases reaction|increases activity 15263067
C402769 tipifarnib tipifarnib results in increased expression of KRAS mRNAincreases expression 16403772
D014028 Tobacco Smoke Pollution Tobacco Smoke Pollution results in increased mutagenesis of KRAS geneincreases mutagenesis 10824542
11745231
D014520 Urethane KRAS gene affects the susceptibility to Urethaneaffects response to substance 11807781
D014520 Urethane Urethane results in decreased expression of KRAS mRNAdecreases expression 16289808
D014520 Urethane Urethane results in increased mutagenesis of KRAS geneincreases mutagenesis 10779650
D014520 Urethane Urethane results in increased mutagenesis of KRAS geneincreases mutagenesis 18271921
D014752 Vinyl Chloride CYP2E1 gene polymorphism promotes the reaction [Vinyl Chloride affects the mutagenesis of KRAS gene]affects mutagenesis|increases reaction 12705718
D014752 Vinyl Chloride CYP2E1 gene polymorphism promotes the reaction [Vinyl Chloride results in increased mutagenesis of KRAS gene]increases mutagenesis|increases reaction 17384900
D014752 Vinyl Chloride Vinyl Chloride results in increased mutagenesis of KRAS geneincreases mutagenesis 10629081
17384900
12670519
12211074
11563603
16881598
D014752 Vinyl Chloride XRCC1 gene polymorphism promotes the reaction [Vinyl Chloride results in increased mutagenesis of KRAS gene]increases mutagenesis|increases reaction 16881598
D014752 Vinyl Chloride KRAS gene polymorphism results in increased susceptibility to Vinyl Chlorideincreases response to substance 12807761
D015215 Zidovudine Zidovudine results in increased mutagenesis of KRAS geneincreases mutagenesis 18800350
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Sulindac 4.9114745880
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.2915322242 11752688 14514962
MESH:D000138 Acidosis Ammonium Chloride 2.9918287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.3617505938
MESH:D000163 Acquired Immunodeficiency Syndrome Zidovudine 4.269612607
MESH:D058186 Acute Kidney Injury resveratrol 7.3116538975
MESH:D058186 Acute Kidney Injury Sulindac 7.317897758
MESH:D055371 Acute Lung Injury Chlorine 7.3920601635
MESH:D055371 Acute Lung Injury pirinixic acid 7.3918653653
MESH:D000230 Adenocarcinoma marker/mechanism 16247444 11745231
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 25.1120127859 20464547
MESH:D000230 Adenocarcinoma Dimethylnitrosamine 25.1116033868
MESH:D000230 Adenocarcinoma Estradiol 25.1111473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 25.1114692618
MESH:D000230 Adenocarcinoma Fluorouracil 25.1117638652
MESH:D000230 Adenocarcinoma Genistein 25.1111473722
MESH:D000230 Adenocarcinoma Methylnitrosourea 25.1115688392 15113128
MESH:D000230 Adenocarcinoma Sulindac 25.1111910360
MESH:D000230 Adenocarcinoma Urethane 25.1118316556
MESH:D002282 Adenocarcinoma, Bronchiolo-Alveolar Tobacco Smoke Pollution 11.5115814487
MESH:D002282 Adenocarcinoma, Bronchiolo-Alveolar Urethane 11.5115814487
MESH:D000236 Adenoma marker/mechanism 10545420
MESH:D000236 Adenoma 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 35.8516176798
MESH:D000236 Adenoma Benzo(a)pyrene 35.856695378
MESH:D000236 Adenoma diisopropanolnitrosamine 35.8510945294
MESH:D000236 Adenoma Dimethylnitrosamine 35.8519555203
MESH:D000236 Adenoma Ethylnitrosourea 35.856695378
MESH:D000236 Adenoma Methylcholanthrene 35.8510545420 6695378
MESH:D000236 Adenoma resveratrol 35.8515688382
MESH:D000236 Adenoma Sulindac 35.8510223192
MESH:D000236 Adenoma Urethane 35.8516926031 17093202 6695378 11497255 10822126 10530776 17195641
MESH:D018248 Adenoma, Liver Cell pirinixic acid 8.0016434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 8.0016835633
MESH:D011125 Adenomatous Polyposis Coli Sulindac 4.1019003578 11535846 15623613 11874996 12394442 16460482 17611924
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.1115276417
MESH:D000309 Adrenal Insufficiency Dehydroepiandrosterone 5.2017302879
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.3216712894 17306315
MESH:D019973 Alcohol-Related Disorders Curcumin 4.5017887948
MESH:D000544 Alzheimer Disease Curcumin 5.7315590663
MESH:D000544 Alzheimer Disease Ozone 5.7315513908
MESH:D000544 Alzheimer Disease resveratrol 5.7316162502 16183991
MESH:D000740 Anemia Fluorouracil 7.0217963324 16511603 15504547
MESH:D000740 Anemia Tetrachlorodibenzodioxin 7.0211748828
MESH:D000741 Anemia, Aplastic Benzene 3.9211369114 14761424 17661222
MESH:D000743 Anemia, Hemolytic Quercetin 3.7217084956
MESH:D000799 Angioedema Acetaminophen 3.2610982225
MESH:D001008 Anxiety Disorders Pentobarbital 4.2718313124 11141031
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.5119183758
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 2.9111256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 6.1115885639
MESH:D001169 Arthritis, Experimental resveratrol 6.1117115116
MESH:D001172 Arthritis, Rheumatoid Curcumin 6.5616807698
MESH:D001172 Arthritis, Rheumatoid Ozone 6.5615570426
MESH:D001172 Arthritis, Rheumatoid Tobacco Smoke Pollution 6.5619898480
MESH:D001249 Asthma Ozone 2.4417854713 16373670
MESH:D001260 Ataxia Telangiectasia Quercetin 4.4015336622
MESH:D050197 Atherosclerosis Asbestos 12.7518795166
MESH:D050197 Atherosclerosis Curcumin 12.7518704882
MESH:D050197 Atherosclerosis Methylcholanthrene 12.7511922910
MESH:D050197 Atherosclerosis resveratrol 12.7517967414 16873680
MESH:D001321 Autistic Disorder Acetaminophen 2.1318445737
MESH:D001321 Autistic Disorder Haloperidol 2.1319368416 18080171
MESH:D001327 Autoimmune Diseases Curcumin 9.0019761891
MESH:D001327 Autoimmune Diseases Quercetin 9.0019761891
MESH:D001661 Biliary Tract Neoplasms Vinyl Chloride 6.2811024202
MESH:D001778 Blood Coagulation Disorders pirinixic acid 7.0619483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 7.0612125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.2115340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.3815746008
MESH:D001855 Bone Marrow Diseases Benzene 4.6416183116
MESH:D001862 Bone Resorption bisphenol A 3.3511985600
MESH:D001913 Bowen's Disease Sulindac 4.7711207687
MESH:D001927 Brain Diseases Ethylnitrosourea 4.3814991843
MESH:D002545 Brain Ischemia Curcumin 8.4216770732
MESH:D002545 Brain Ischemia resveratrol 8.4217600658
MESH:D001932 Brain Neoplasms 1,3-butadiene 16.9216860786
MESH:D001932 Brain Neoplasms Curcumin 16.9217596214
MESH:D001932 Brain Neoplasms Ethylnitrosourea 16.9218412241 16436596 16357521 16651633 15144691
MESH:D001932 Brain Neoplasms Vinyl Chloride 16.9212562636
MESH:D001943 Breast Neoplasms marker/mechanism
MESH:D001943 Breast Neoplasms 1,3-butadiene 19.5611921183 12165863
MESH:D001943 Breast Neoplasms 2,2-bis(bromomethyl)-1,3-propanediol 19.5611921183
MESH:D001943 Breast Neoplasms 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 19.5620146248
MESH:D001943 Breast Neoplasms Benzene 19.5617162533 11921183
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 19.5620146248 17474063
MESH:D001943 Breast Neoplasms bisphenol A 19.5617123778
MESH:D001943 Breast Neoplasms Chloroprene 19.5611921183
MESH:D001943 Breast Neoplasms Curcumin 19.5619250217 18593918 18462866 16243823
MESH:D001943 Breast Neoplasms Estradiol 19.5614630087 17289903 18497071 12948864 17018787 16675129 19861407 17261762
MESH:D001943 Breast Neoplasms Fluorouracil 19.5618608205 16557594 15136595 16595493 19217205 16110121 18357371
MESH:D001943 Breast Neoplasms Genistein 19.5616873071 16541309 17200150
MESH:D001943 Breast Neoplasms isoprene 19.5611921183
MESH:D001943 Breast Neoplasms Methylcholanthrene 19.5617474063
MESH:D001943 Breast Neoplasms Methylnitrosourea 19.5616253758 11306469 14633655
MESH:D001943 Breast Neoplasms Quercetin 19.5618628248
MESH:D001943 Breast Neoplasms resveratrol 19.5616393696 17651959 17534123
MESH:D001943 Breast Neoplasms Styrene 19.5615986119
MESH:D001943 Breast Neoplasms Sulindac 19.5616642371
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 19.5620435547
MESH:D016535 Bronchial Hyperreactivity Ozone 3.2215516495 19059883 18315731 16777450 18417511 14754758 17626835
MESH:D002100 Cachexia Ozone 4.1716183385
MESH:D002105 Cadmium Poisoning Quercetin 4.9616962696
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 3.8916111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.2216011737 15673190 18705752 16227642 16097048 15700767 16124888 16050911 10355542 15721981 3786805 16192424
MESH:D002276 Carcinoid Tumor Fluorouracil 4.0816051944
MESH:D002277 Carcinoma marker/mechanism 10545420
MESH:D002277 Carcinoma Curcumin 26.5818593918
MESH:D002277 Carcinoma diisopropanolnitrosamine 26.5810463772 11442016 10945294
MESH:D002277 Carcinoma Dimethylnitrosamine 26.5819555203
MESH:D002277 Carcinoma Fluorouracil 26.5817121937
MESH:D002277 Carcinoma Methylcholanthrene 26.5810545420
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 26.5816835633
MESH:D006528 Carcinoma, Hepatocellular marker/mechanism 11286481 11563603
MESH:D006528 Carcinoma, Hepatocellular 2,2-bis(bromomethyl)-1,3-propanediol 23.0816362062
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 23.0816705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 23.083084413
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 23.0818788625
MESH:D006528 Carcinoma, Hepatocellular Estradiol 23.0816924424
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 23.0817088986 16332177 18930000 17045692 17971768 16799960
MESH:D006528 Carcinoma, Hepatocellular Genistein 23.0816924424
MESH:D006528 Carcinoma, Hepatocellular Quercetin 23.0819519916 12508355
MESH:D006528 Carcinoma, Hepatocellular resveratrol 23.0816227395 19321006
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 23.0815276417 17306315 16507464
MESH:D006528 Carcinoma, Hepatocellular Vinyl Chloride 23.0812958735 15289165 12828392 10699891
MESH:D002278 Carcinoma in Situ bisphenol A 4.4117123778
MESH:D018827 Carcinoma, Lewis Lung resveratrol 4.0216675471
MESH:D002289 Carcinoma, Non-Small-Cell Lung Curcumin 5.1318414057
MESH:D002289 Carcinoma, Non-Small-Cell Lung Tobacco Smoke Pollution 5.1311212258
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.3917234771
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 2.7218695887
MESH:D002294 Carcinoma, Squamous Cell marker/mechanism 19435901
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 22.4120419170
MESH:D002294 Carcinoma, Squamous Cell Curcumin 22.4118462866
MESH:D002294 Carcinoma, Squamous Cell Dimethylnitrosamine 22.4116033868
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 22.4116757204 18986760 16280240 17066447
MESH:D002294 Carcinoma, Squamous Cell resveratrol 22.4116227395
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 22.4118572023
MESH:D002294 Carcinoma, Squamous Cell Tetradecanoylphorbol Acetate 22.4118922899
MESH:D002294 Carcinoma, Squamous Cell Tobacco Smoke Pollution 22.4111212258
MESH:C535579 Cardiofaciocutaneous syndrome marker/mechanism 17703371
MESH:D006332 Cardiomegaly Quercetin 5.6519794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 5.6518670907 18850075 16120746
MESH:D002318 Cardiovascular Diseases Genistein 6.1416332659
MESH:D002318 Cardiovascular Diseases resveratrol 6.1415458977
MESH:D002375 Catalepsy Haloperidol 4.3415215559 1977408
MESH:D002386 Cataract Acetaminophen 6.3510977129
MESH:D002386 Cataract Methylnitrosourea 6.3512484553
MESH:D002430 Cecal Neoplasms marker/mechanism 14688030
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 25.5220889678
MESH:D002471 Cell Transformation, Neoplastic diisopropanolnitrosamine 25.521399818 7505956
MESH:D002471 Cell Transformation, Neoplastic Estradiol 25.5218566989
MESH:D002471 Cell Transformation, Neoplastic Ethylnitrosourea 25.5216003739
MESH:D002471 Cell Transformation, Neoplastic Methylcholanthrene 25.5216192471
MESH:D002471 Cell Transformation, Neoplastic Methylnitrosourea 25.522727394 7505956
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 25.5219524636 20056578
MESH:D016543 Central Nervous System Neoplasms Ethylnitrosourea 5.4017160924
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 2.6716835633
MESH:D002779 Cholestasis Ethinyl Estradiol 6.2917110522 16919318 15861022 16105132 17333356 17681005 11677210
MESH:D002779 Cholestasis pirinixic acid 6.2919176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.2515668235 15340226 12621046 16354765 8697196
MESH:D002972 Cleft Palate Urethane 5.2512810352
MESH:D003092 Colitis Curcumin 7.9418200517 16782535 16804969
MESH:D003092 Colitis resveratrol 7.9416474422
MESH:D003103 Coloboma Curcumin 4.0318809619
MESH:D003110 Colonic Neoplasms marker/mechanism 18372904 19424582
MESH:D003110 Colonic Neoplasms Curcumin 12.2016340194 19359593
MESH:D003110 Colonic Neoplasms Fluorouracil 12.2016340194 17725105 17287894 15001691 17172411 16510598 18772588 17018589 17169374 17016597
MESH:D003110 Colonic Neoplasms Genistein 12.2017182828
MESH:D003110 Colonic Neoplasms Quercetin 12.2015741050 16640504 17191121 11134977 19056647 19440933 17148506
MESH:D003110 Colonic Neoplasms resveratrol 12.2016338953
MESH:D003110 Colonic Neoplasms Sulindac 12.2012458338 12902858
MESH:D015179 Colorectal Neoplasms Fluorouracil 5.6817094418 17454858 14970324 17401013 17594712 15148649 18448328 18383874 17016601 18802399 18288408 20501625 16282729 17695437 16391804 16331619 15289873 18509181 18949393 16303861 17255274 16524972
MESH:D015179 Colorectal Neoplasms Polychlorinated Biphenyls 5.6815531428
MESH:D015179 Colorectal Neoplasms Quercetin 5.6818852136 18095365
MESH:D015179 Colorectal Neoplasms resveratrol 5.6816550006
MESH:D015179 Colorectal Neoplasms Sulindac 5.6818059344 10666051 11076880 11197048
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.5717141729 14669216
MESH:D016510 Corneal Neovascularization Curcumin 4.3318497527
MESH:D003327 Coronary Disease resveratrol 3.3616507316
MESH:D056685 Costello Syndrome marker/mechanism 17703371 17468812
MESH:D019465 Craniofacial Abnormalities Benzene 2.4515643154
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.4510048152 15322242 20055451
MESH:D003490 Cyanosis 2,4-dinitrotoluene 3.4518551238
MESH:D007644 Darier Disease Fluorouracil 4.2216733453
MESH:D016757 Death, Sudden, Cardiac Haloperidol 4.3120210726
MESH:D003704 Dementia Haloperidol 8.6211575062
MESH:D003704 Dementia Polychlorinated Biphenyls 8.6216140633
MESH:D003872 Dermatitis Benzene 4.2115902427
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.1318249437
MESH:D009783 Dermatitis, Occupational Vinyl Chloride 5.1310870345
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 6.9919496084
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 6.9916873680
MESH:D003922 Diabetes Mellitus, Type 1 Dehydroepiandrosterone 3.4916616286
MESH:D003924 Diabetes Mellitus, Type 2 Curcumin 6.1218403477
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 6.1216647724
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 6.1217107852
MESH:D003928 Diabetic Nephropathies Curcumin 12.2818204486
MESH:D003928 Diabetic Nephropathies Estradiol 12.2819279558
MESH:D003928 Diabetic Nephropathies resveratrol 12.2816286809
MESH:D003930 Diabetic Retinopathy Sulindac 4.6317621415 12861449
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 9.7621346803 18551238
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 9.7617562736 16227642 19923254 16781746 14550746 15968718 10774834 11834606 19164858 10915739 2444490 19416960 12540782 18071297 12153990 17906064 16393943 16177239 11529661 17522070 11743745 14725611 19420014 19739265 15619225 11287661 12594235 19085960 12392966 16109766 11739529 16081117 16485898 11461765 19370779 14986274 18713872 12705907 10663392 12958197 11421492
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 9.7611566570 16227642 6623471 7440962 7120509 16177239 19336974 15968718 7179309 2869522 21278145 9327722 6884620 19085960 15027814 10915739 3786805 17522070 15998439 4309450 3732212 10092053
MESH:D056486 Drug-Induced Liver Injury Dimethylnitrosamine 9.768172417
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 9.7620420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.5119426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 6.7811462148
MESH:D004362 Drug Toxicity Zidovudine 6.7815040536
MESH:D004381 Duodenal Ulcer Curcumin 3.5117351913
MESH:D004417 Dyspnea Chlorine 4.0420016425
MESH:D004476 Ectodermal Dysplasia Ethylnitrosourea 5.4018357618
MESH:D004487 Edema pirinixic acid 12.2912083418
MESH:D004487 Edema resveratrol 12.298985016
MESH:D004487 Edema Tetrachlorodibenzodioxin 12.2912711302 11000095
MESH:D004487 Edema Tetradecanoylphorbol Acetate 12.2916716910 9599246 11698051 8273558 15177302 7812673 8113982
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.3215322242 18230668 16714409
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 7.3212538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 7.3217872969
MESH:D004714 Endometrial Hyperplasia Genistein 4.0116402032
MESH:D016889 Endometrial Neoplasms Estradiol 6.1911473722 19148513 18566989
MESH:D016889 Endometrial Neoplasms Genistein 6.1911473722
MESH:D004715 Endometriosis Sulindac 7.5315652904
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 7.5310568697 9294722
MESH:D020345 Enterocolitis, Necrotizing resveratrol 4.2917923197
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 15.0320426865
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 15.0316530937
MESH:D004938 Esophageal Neoplasms diisopropanolnitrosamine 15.031399818
MESH:D004938 Esophageal Neoplasms Dimethylnitrosamine 15.0317016578
MESH:D004938 Esophageal Neoplasms Fluorouracil 15.0315173087 17638652 16481741 16785472 16337965
MESH:D004938 Esophageal Neoplasms Sulindac 15.0312235107
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.5711564622
MESH:D005234 Fatty Liver Carbon Tetrachloride 24.0915959796 17595544 12631006 19224547 12795759 61145 16045604 16239168
MESH:D005234 Fatty Liver Curcumin 24.0919297423
MESH:D005234 Fatty Liver Ethinyl Estradiol 24.0915345470
MESH:D005234 Fatty Liver pirinixic acid 24.0920131406 19236843
MESH:D005234 Fatty Liver Vinyl Chloride 24.0912197357
MESH:D005234 Fatty Liver Zidovudine 24.0918299183
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 2.9011858732
MESH:D018221 Fibromatosis, Abdominal Sulindac 4.9014745880
MESH:D018222 Fibromatosis, Aggressive Sulindac 4.5619069698
MESH:D005354 Fibrosarcoma Methylcholanthrene 10.3114633661 10962813
MESH:D005354 Fibrosarcoma Methylnitrosourea 10.3111555667
MESH:D005355 Fibrosis Carbon Tetrachloride 16.6118705752
MESH:D005355 Fibrosis Curcumin 16.6118705752
MESH:D005355 Fibrosis Quercetin 16.6119474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 16.6120067830
MESH:D005739 Gas Poisoning Chlorine 4.4220016425
MESH:D005756 Gastritis Acetaminophen 3.0916983495
MESH:D005764 Gastroesophageal Reflux Sulindac 4.4611910360
MESH:D005770 Gastrointestinal Neoplasms Curcumin 4.1318462866
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.1016452187
MESH:D005909 Glioblastoma Curcumin 13.7917596214
MESH:D005909 Glioblastoma Ethylnitrosourea 13.7916436596
MESH:D005909 Glioblastoma Genistein 13.7916598420
MESH:D005909 Glioblastoma Quercetin 13.7919804834
MESH:D005910 Glioma 1,3-butadiene 15.8515814359
MESH:D005910 Glioma Ethylnitrosourea 15.8518412241 16651633 16357521
MESH:D005910 Glioma Fluorouracil 15.8516145905
MESH:D005910 Glioma Methylnitrosourea 15.859825942
MESH:D005910 Glioma Quercetin 15.8517643826
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.0110696789
MESH:D006258 Head and Neck Neoplasms Curcumin 6.6218829502 18462866
MESH:D006258 Head and Neck Neoplasms Fluorouracil 6.6215102660 15162350 18337622
MESH:D034381 Hearing Loss Styrene 4.9117420221
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 5.3420471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 5.3410048152 11294989
MESH:D006331 Heart Diseases Urethane 3.8316046796
MESH:D006333 Heart Failure pirinixic acid 2.1720558911
MESH:D006390 Hemangioendothelioma Vinyl Chloride 5.5915380572
MESH:D006393 Hemangiopericytoma Vinyl Chloride 6.2810964802
MESH:D006394 Hemangiosarcoma marker/mechanism 10930038 12211074 13678655
MESH:D006394 Hemangiosarcoma 1,3-butadiene 8.6110930038 2208121
MESH:D006394 Hemangiosarcoma Vinyl Chloride 8.6115999577 12762079 11217710 12828392 12958735 15989139 12211074
MESH:D006402 Hematologic Diseases Benzene 9.3116183116
MESH:D006402 Hematologic Diseases Zidovudine 9.3112579204
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.8211000095
MESH:D006505 Hepatitis Carbon Tetrachloride 3.0519900420 19110552
MESH:D006529 Hepatomegaly pirinixic acid 6.4119176532 16221962 18467677 19772884
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 6.4115340226 16120746 12621046
MESH:D015417 Hereditary Sensory and Motor Neuropathy Curcumin 4.4817701891
MESH:D006558 Herpes Genitalis Estradiol 4.4415709030
MESH:D006561 Herpes Simplex resveratrol 3.6116876885
MESH:D015658 HIV Infections Zidovudine 3.1711363243 20032539 11141242 11698656 17358032
MESH:D019247 HIV Wasting Syndrome testosterone enanthate 5.1617440010
MESH:D006689 Hodgkin Disease sodium arsenite 2.6812676792
MESH:D019584 Hot Flashes Estradiol 3.1717088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.4615340226 16354765 8697196 16959395 18606429
MESH:D006930 Hyperalgesia Acetaminophen 2.2516870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 3.9616899240
MESH:D006937 Hypercholesterolemia Curcumin 7.6718704882
MESH:D006937 Hypercholesterolemia resveratrol 7.6717188708
MESH:D006943 Hyperglycemia pirinixic acid 7.5820558911
MESH:D006943 Hyperglycemia Quercetin 7.5811834736 18262572
MESH:D006949 Hyperlipidemias resveratrol 3.5016873680
MESH:D006973 Hypertension Benzene 7.2217940673
MESH:D006973 Hypertension Quercetin 7.2218356687
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 7.2218850075 18670907
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.5315338365
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 3.8017488730
MESH:D007021 Hypospadias Ethinyl Estradiol 3.2516945680 16569931
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 4.0917600658
MESH:D007246 Infertility 2,2-bis(bromomethyl)-1,3-propanediol 5.652792593
MESH:D007247 Infertility, Female Ethinyl Estradiol 2.9312013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 8.9917937319
MESH:D007248 Infertility, Male Methylnitrosourea 8.997193160
MESH:D007248 Infertility, Male sodium arsenite 8.9912646999 15346721
MESH:D007249 Inflammation Curcumin 15.7117151092 18403477 16956363
MESH:D007249 Inflammation resveratrol 15.7116366677
MESH:D007249 Inflammation Sulindac 15.713291741
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 15.7112200463 12878042
MESH:D007249 Inflammation Tetradecanoylphorbol Acetate 15.717562506 8273558 15177302 7812673 11698051
MESH:D007249 Inflammation Tobacco Smoke Pollution 15.7118590791
MESH:D015212 Inflammatory Bowel Diseases Curcumin 2.9518596194 18200517
MESH:D007251 Influenza, Human Quercetin 9.2516624496
MESH:D007251 Influenza, Human resveratrol 9.2516624496
MESH:D007333 Insulin Resistance bisphenol A 10.0316393666
MESH:D007333 Insulin Resistance Estradiol 10.0316393666 16627594
MESH:D007333 Insulin Resistance pirinixic acid 10.0316306350
MESH:D007410 Intestinal Diseases rebamipide 4.6211686837
MESH:D007414 Intestinal Neoplasms Curcumin 8.4510783313
MESH:D007414 Intestinal Neoplasms Sulindac 8.4510223192 12628509 12663524 10213222 12351151 12584176
MESH:D007417 Intestinal Polyps Sulindac 4.4611245490 12394442
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 2.8216580747
MESH:D007627 Keloid Quercetin 4.3917086741
MESH:D007674 Kidney Diseases Acetaminophen 11.5215629191 12587719
MESH:D007674 Kidney Diseases Estradiol 11.5215618244
MESH:D007674 Kidney Diseases Quercetin 11.5216962696
MESH:D007674 Kidney Diseases sodium arsenite 11.5220008137
MESH:D007680 Kidney Neoplasms 2,2-bis(bromomethyl)-1,3-propanediol 43.349437797 2731663 12594523
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 43.3416705839
MESH:D007680 Kidney Neoplasms Chloroprene 43.3412562636
MESH:D007680 Kidney Neoplasms diisopropanolnitrosamine 43.346582329
MESH:D007680 Kidney Neoplasms Estradiol 43.3415610895
MESH:D007680 Kidney Neoplasms Ethylnitrosourea 43.3417379185
MESH:D007680 Kidney Neoplasms Fluorouracil 43.3416985049
MESH:D007680 Kidney Neoplasms isoprene 43.3412562636
MESH:D007680 Kidney Neoplasms Vinyl Chloride 43.3412562636
MESH:D007680 Kidney Neoplasms Zidovudine 43.3412579204
MESH:D007889 Leiomyoma Curcumin 4.0418555241
MESH:D007938 Leukemia 1,3-butadiene 20.5516155477
MESH:D007938 Leukemia 2,2-bis(bromomethyl)-1,3-propanediol 20.5512594523
MESH:D007938 Leukemia Benzene 20.5514694614 15935818 18335105 17119257
MESH:D007938 Leukemia Curcumin 20.5518462866
MESH:D007938 Leukemia Genistein 20.5518980019 17468513
MESH:D007938 Leukemia Quercetin 20.5517468513
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Curcumin 8.2816106398
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Zidovudine 8.2820370541
MESH:D007951 Leukemia, Myeloid Benzene 8.4517506065
MESH:D007951 Leukemia, Myeloid Hydroxyurea 8.4516532439
MESH:D015470 Leukemia, Myeloid, Acute Benzene 2.5919478238
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 3.1916087638
MESH:D015458 Leukemia, T-Cell Curcumin 4.2116106398
MESH:D017880 Limb Deformities, Congenital Methylnitrosourea 3.7815526292
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 6.1117157831 17334410 11903743 16943688 16221502 11408273 17174718 21278145 16239168
MESH:D008103 Liver Cirrhosis Vinyl Chloride 6.1111679801 12499459 12958735 15354062 15289165
MESH:D008105 Liver Cirrhosis, Biliary Sulindac 3.8412468960
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 11.4818395914 15959796 18412020 18210741 16136751 15123356 18006644 18156304 17557913 12667390 17481882 11481614 14620537 15893842 12898905 14724832 18472094 12632512 18277467 20821823 18054572 18420326 14748882 15052691 16015684 17640975 12546737 18205269 18376398 17805973 17869086 18418968 18251166 17525996 17714472 16116963 18472332 15650968 14716496 15338365 16638106 17900296 12445418 16033810 15818738 18263696 17922224 15362042 14512876 18395095 15370692 15996030 12666154 12609069 17823541 18429990 12389079 18187930 12649538 17944888 17698563 15057751 15931870 18166357 15925388 16248980 15673190 18279442 15730626 13678700 12632514 16011737 17761835 16192424 17708605 17631135 12445421 14716833 16097048 12958196 18705752 12741479 17565644 16027843 18339082 17976157 18317297 18481824 17721639 15876570 12586293 17766677 10355542
MESH:D008106 Liver Cirrhosis, Experimental Curcumin 11.4818006644 18705752 17355460
MESH:D008106 Liver Cirrhosis, Experimental Dimethylnitrosamine 11.4818095165 15942678 18637143 17881167 15504291 16270385 15723089 17640959 14568256 15067225 15369754 15366600 17534399 17196135 15793283 15138612 15798949 17465448 17666798 15099470 15161499 15842777 15571005 16544323 15591649 15479170 17201889 15339415 17198567 15298665 16009107 18371158 17724770 18210741 17203207 12918455 18567088 18237412 18239293 15733078 16169303 14659978 17036385 17719030 14643895 15086199 16603200 16042886 16570917 12925901 16627068 14709902 15383259 18364076 18629640 18672772 15577212 17348192 15492853 15081153 14726149 15864749 15744066 15763062 17432682
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 11.4814659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental Genistein 11.4817823541
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 11.4815474484
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 11.4812741479
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 11.4812878042
MESH:D008107 Liver Diseases Acetaminophen 10.5419014921 16611625 19460945 12969438 11587558 16610002 19784758 12587719
MESH:D008107 Liver Diseases Carbon Tetrachloride 10.5415830285 17285989 15720792 16964402 16246199
MESH:D008107 Liver Diseases Curcumin 10.5416956363
MESH:D008107 Liver Diseases Sulindac 10.5414986274 16867024
MESH:D008107 Liver Diseases Vinyl Chloride 10.5416270392 15211785
MESH:D017093 Liver Failure Carbon Tetrachloride 3.6015123358
MESH:D017114 Liver Failure, Acute Acetaminophen 13.3616871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 13.3614706259 16899240
MESH:D017114 Liver Failure, Acute Dimethylnitrosamine 13.3617457977
MESH:D008113 Liver Neoplasms marker/mechanism 10629081 12211074
MESH:D008113 Liver Neoplasms 1,3-butadiene 44.792208121
MESH:D008113 Liver Neoplasms 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 44.7915890375
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 44.7920195826 21137059
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 44.7919294768
MESH:D008113 Liver Neoplasms Dehydroepiandrosterone 44.7918709148
MESH:D008113 Liver Neoplasms Dimethylnitrosamine 44.793113478 15890375
MESH:D008113 Liver Neoplasms Fluorouracil 44.7918383874 17045692 15113037 16603448
MESH:D008113 Liver Neoplasms pirinixic acid 44.7920007298 16377806 15890375
MESH:D008113 Liver Neoplasms Quercetin 44.7918980244
MESH:D008113 Liver Neoplasms resveratrol 44.7919321006 19812893 19073162 20405173
MESH:D008113 Liver Neoplasms sodium arsenite 44.7916712894 15276417
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 44.7916984957
MESH:D008113 Liver Neoplasms Urethane 44.7917093202 17559639 16391232
MESH:D008113 Liver Neoplasms Vinyl Chloride 44.7915999577 10964802 12211074 10629081 11024202 12762079 11679801
MESH:D008114 Liver Neoplasms, Experimental marker/mechanism 8603461
MESH:D008114 Liver Neoplasms, Experimental Benzene 44.6212562636
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 44.6215583823 12014681
MESH:D008114 Liver Neoplasms, Experimental Chloroprene 44.6212562636
MESH:D008114 Liver Neoplasms, Experimental Dehydroepiandrosterone 44.628603461
MESH:D008114 Liver Neoplasms, Experimental diisopropanolnitrosamine 44.621399818
MESH:D008114 Liver Neoplasms, Experimental Dimethylnitrosamine 44.6215603536 6150874 1848544
MESH:D008114 Liver Neoplasms, Experimental isoprene 44.6212562636
MESH:D008114 Liver Neoplasms, Experimental Methylcholanthrene 44.621399818 598648
MESH:D008114 Liver Neoplasms, Experimental Polychlorinated Biphenyls 44.621423854
MESH:D008114 Liver Neoplasms, Experimental Quercetin 44.6219519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 44.6212151625
MESH:D008114 Liver Neoplasms, Experimental Vinyl Chloride 44.6212562636
MESH:D038061 Lower Extremity Deformities, Congenital Methylnitrosourea 4.9016080182
MESH:D008171 Lung Diseases Ozone 6.188266340 19066396
MESH:D008171 Lung Diseases sodium arsenite 6.1819095001
MESH:D017563 Lung Diseases, Interstitial Benzene 4.2214698565
MESH:D055370 Lung Injury Ozone 3.3020417186
MESH:D008175 Lung Neoplasms marker/mechanism 11745231 12725029 12376484 18758463 11641043 16247444 16289808 16823377 17325976 7750092 10545420 10223196 16410370 17233834 16271038 18062963 19424582 8597069 7614698 17290066 19555203 11884234
MESH:D008175 Lung Neoplasms 1,3-butadiene 70.3416860786 17372256 2208121
MESH:D008175 Lung Neoplasms 2,2-bis(bromomethyl)-1,3-propanediol 70.349437797 12594523
MESH:D008175 Lung Neoplasms 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 70.3418813816 14755239 9255578 16401635 16061637 15893417 15172992 17139156 12438228 19931552 18508827
MESH:D008175 Lung Neoplasms Asbestos 70.3412111688
MESH:D008175 Lung Neoplasms Benzene 70.3412562636
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 70.3420064080 18816296 20869020 20464547 18520028 18569708 17053015 20135361 6695378
MESH:D008175 Lung Neoplasms Chloroprene 70.3410223196 12562636
MESH:D008175 Lung Neoplasms Curcumin 70.3419359593 16243823 18462866
MESH:D008175 Lung Neoplasms diisopropanolnitrosamine 70.341399818
MESH:D008175 Lung Neoplasms Dimethylnitrosamine 70.3416061637 19555203 11884234
MESH:D008175 Lung Neoplasms Ethylnitrosourea 70.3417703301 16019985 6695378 16271038
MESH:D008175 Lung Neoplasms Fluorouracil 70.3415246190
MESH:D008175 Lung Neoplasms isoprene 70.3412562636
MESH:D008175 Lung Neoplasms Methylcholanthrene 70.3416337739 11893704 20970405 21163286 17909032 10545420 20512841 7750092 1399818 15390079 9230183 16271038 6695378
MESH:D008175 Lung Neoplasms Methylnitrosourea 70.3418062963
MESH:D008175 Lung Neoplasms Ozone 70.348597069 7614698
MESH:D008175 Lung Neoplasms Quercetin 70.3416280456
MESH:D008175 Lung Neoplasms sodium arsenite 70.3417306315 17077188 16712894 19931552 15276417
MESH:D008175 Lung Neoplasms Styrene 70.3412562636
MESH:D008175 Lung Neoplasms Sulindac 70.3419359593 15713900
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 70.3419555203 11884234
MESH:D008175 Lung Neoplasms Tetradecanoylphorbol Acetate 70.3411807781
MESH:D008175 Lung Neoplasms Tetranitromethane 70.349255578 14713543
MESH:D008175 Lung Neoplasms tipifarnib 70.3416885199
MESH:D008175 Lung Neoplasms Tobacco Smoke Pollution 70.3416288123 3440675 11091918 12111688
MESH:D008175 Lung Neoplasms Urethane 70.3417255336 11062179 12765245 11246140 16204055 15902970 11323394 12117781 12466968 10530776 16926031 11497255 12957351 16007126 11807781 16391232 11893704 7750092 10997738 11552296 15166089 15136453 16289808 16337739 11544531 17093202 11992545 11074608 6695378 11307925 10822126 16788158 10779650 17195641 14587096
MESH:D008175 Lung Neoplasms Vinyl Chloride 70.3412958735 12562636
MESH:D008175 Lung Neoplasms Zidovudine 70.3418800350
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.2215086387
MESH:D008223 Lymphoma marker/mechanism 9205081
MESH:D008223 Lymphoma 1,3-butadiene 19.0317941976 11980663 9205081 8764131 9488045 2208121 18798262
MESH:D008223 Lymphoma Benzene 19.0317119257 17584886
MESH:D008223 Lymphoma Curcumin 19.0318462866
MESH:D008223 Lymphoma Ethylnitrosourea 19.0315790496
MESH:D008223 Lymphoma Methylnitrosourea 19.0311418001 16257854
MESH:D016393 Lymphoma, B-Cell Methylnitrosourea 8.7714633661
MESH:D016393 Lymphoma, B-Cell resveratrol 8.7717088997
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 3.4014749477
MESH:D016399 Lymphoma, T-Cell Curcumin 9.8816173963
MESH:D016399 Lymphoma, T-Cell Ethylnitrosourea 9.8815375218
MESH:D015674 Mammary Neoplasms, Animal 1,3-butadiene 38.012208121
MESH:D015674 Mammary Neoplasms, Animal Benzene 38.0112562636
MESH:D015674 Mammary Neoplasms, Animal Chloroprene 38.0112562636
MESH:D015674 Mammary Neoplasms, Animal isoprene 38.0112562636
MESH:D015674 Mammary Neoplasms, Animal resveratrol 38.0115688416
MESH:D015674 Mammary Neoplasms, Animal Styrene 38.0112562636
MESH:D015674 Mammary Neoplasms, Animal Vinyl Chloride 38.0112562636
MESH:D008325 Mammary Neoplasms, Experimental 1,3-butadiene 49.6111921183
MESH:D008325 Mammary Neoplasms, Experimental 2,2-bis(bromomethyl)-1,3-propanediol 49.6111921183
MESH:D008325 Mammary Neoplasms, Experimental Benzene 49.6111921183
MESH:D008325 Mammary Neoplasms, Experimental Chloroprene 49.6111921183
MESH:D008325 Mammary Neoplasms, Experimental Dehydroepiandrosterone 49.6116457693
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 49.6117203775 11807958 16891317 11408345
MESH:D008325 Mammary Neoplasms, Experimental Ethylnitrosourea 49.6110767621 10838139 18041768
MESH:D008325 Mammary Neoplasms, Experimental Genistein 49.6112929590 14578162
MESH:D008325 Mammary Neoplasms, Experimental isoprene 49.6111921183
MESH:D008325 Mammary Neoplasms, Experimental Methylnitrosourea 49.6115113128 16944150 16619500 17131329 11807958 15688392 10767621 16827153 12931682 14633655 11751437 19196723 15313902 10838139 14999141 16051031 17020996
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 49.618985016 11606380
MESH:D008325 Mammary Neoplasms, Experimental Tetradecanoylphorbol Acetate 49.618985016
MESH:D008325 Mammary Neoplasms, Experimental tipifarnib 49.6116648579
MESH:D020149 Manganese Poisoning Estradiol 3.9019453300
MESH:D008545 Melanoma Curcumin 6.2518462866 17885582
MESH:D008545 Melanoma resveratrol 6.2517992120
MESH:D008545 Melanoma sodium arsenite 6.2519082730 16487513
MESH:D008545 Melanoma Sulindac 6.2516642371
MESH:D008546 Melanoma, Experimental Acetaminophen 3.0119513568
MESH:D008569 Memory Disorders Curcumin 3.6117263510
MESH:D008579 Meningioma Ethylnitrosourea 5.4017943659
MESH:D001523 Mental Disorders Haloperidol 3.4616856516
MESH:D008654 Mesothelioma Asbestos 3.8316564556 18310086 16319530 16919927 18709470
MESH:D008659 Metabolic Diseases resveratrol 3.8617112576
MESH:D008679 Metaplasia Ozone 4.5210496685
MESH:D048629 Micronuclei, Chromosome-Defective Zidovudine 5.2517358032
MESH:D009062 Mouth Neoplasms marker/mechanism 19435901
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 16.9616381670
MESH:D009062 Mouth Neoplasms Chloroprene 16.9612562636
MESH:D009062 Mouth Neoplasms Fluorouracil 16.9618986760 16757204
MESH:D009062 Mouth Neoplasms Tobacco Smoke Pollution 16.9615006635
MESH:D009101 Multiple Myeloma Benzene 9.8317119195
MESH:D009101 Multiple Myeloma Curcumin 9.8319372569
MESH:D009101 Multiple Myeloma resveratrol 9.8316490592 17935668 17049120 14749477 16267019 17164350
MESH:D009134 Muscular Atrophy, Spinal Curcumin 10.5017962980
MESH:D009134 Muscular Atrophy, Spinal resveratrol 10.5017962980
MESH:D009135 Muscular Diseases pirinixic acid 2.9516239165
MESH:D009203 Myocardial Infarction Genistein 11.3017141266
MESH:D009203 Myocardial Infarction pirinixic acid 11.3019151258
MESH:D009203 Myocardial Infarction Quercetin 11.3019595682
MESH:D009203 Myocardial Infarction resveratrol 11.3017015251 16525036 16317513 17188708 16456233 17125593
MESH:D017202 Myocardial Ischemia resveratrol 7.4717125593 17015251
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 7.4712213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 16.6116810080
MESH:D015428 Myocardial Reperfusion Injury Genistein 16.6117141266
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 16.6116411023
MESH:D015428 Myocardial Reperfusion Injury Quercetin 16.6119207477
MESH:D009205 Myocarditis resveratrol 4.1817322642
MESH:D009336 Necrosis 2,4-dinitrotoluene 3.2918551238
MESH:D009361 Neoplasm Invasiveness Curcumin 3.8318495463
MESH:D009369 Neoplasms Benzo(a)pyrene 22.8511141357
MESH:D009369 Neoplasms Fluorouracil 22.8518600527 18239605 16928823
MESH:D009369 Neoplasms Methylnitrosourea 22.8515533788
MESH:D009369 Neoplasms pirinixic acid 22.8517405874
MESH:D009369 Neoplasms Quercetin 22.8515185748
MESH:D009369 Neoplasms sodium arsenite 22.8511559025
MESH:D009369 Neoplasms Urethane 22.8515625555
MESH:D009369 Neoplasms Vinyl Chloride 22.8511911487
MESH:D009374 Neoplasms, Experimental marker/mechanism 9205081
MESH:D009374 Neoplasms, Experimental 1,3-butadiene 28.178764131 9205081 9488045
MESH:D009374 Neoplasms, Experimental Ethylnitrosourea 28.1716707424
MESH:D009374 Neoplasms, Experimental Methylnitrosourea 28.1712696579
MESH:D009374 Neoplasms, Experimental resveratrol 28.178985016
MESH:D009374 Neoplasms, Experimental sodium arsenite 28.1720056578
MESH:D009374 Neoplasms, Experimental Urethane 28.1715582191
MESH:D009376 Neoplasms, Hormone-Dependent Curcumin 3.9512497104
MESH:D009389 Neovascularization, Pathologic Estradiol 3.1617289903
MESH:D009421 Nervous System Malformations bisphenol A 18.9816427766 11399458
MESH:D009421 Nervous System Malformations Estradiol 18.9811399458 16427766
MESH:D009421 Nervous System Malformations Genistein 18.9816427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 18.9814600291
MESH:D009423 Nervous System Neoplasms Curcumin 5.0418462866
MESH:D009436 Neural Tube Defects Benzene 6.2315643154
MESH:D009436 Neural Tube Defects sodium arsenite 6.2312854658
MESH:D009442 Neurilemmoma Ethylnitrosourea 11.3717160924 16651423 16003739
MESH:D009442 Neurilemmoma Methylnitrosourea 11.3711555667
MESH:D009447 Neuroblastoma 1,3-butadiene 4.5615814359
MESH:D019636 Neurodegenerative Diseases Acetaminophen 11.4418514411
MESH:D019636 Neurodegenerative Diseases resveratrol 11.4417652729
MESH:D019636 Neurodegenerative Diseases Sulindac 11.4417266991 16850258
MESH:D020078 Neurogenic Inflammation Quercetin 8.9317929310
MESH:D020078 Neurogenic Inflammation resveratrol 8.9317929310
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.0316436463
MESH:D009634 Noonan Syndrome marker/mechanism 17468812 17703371 17603482 17603483
MESH:C537847 Noonan syndrome 3 marker/mechanism
MESH:D009669 Nose Neoplasms diisopropanolnitrosamine 5.1710463772 11442016 10945294
MESH:D009765 Obesity Curcumin 4.0119297423
MESH:D009765 Obesity pirinixic acid 4.0120558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 12.5216049721 12819281
MESH:D009784 Occupational Diseases Benzene 12.5217479406 15935809 17119257 15727169 15576619 15913788 17178637 16737584 15612468
MESH:D009784 Occupational Diseases Vinyl Chloride 12.5212061072
MESH:D009837 Oligodendroglioma Ethylnitrosourea 5.4017160924
MESH:D010024 Osteoporosis Curcumin 6.1118719352
MESH:D010024 Osteoporosis Genistein 6.1119401787
MESH:D015663 Osteoporosis, Postmenopausal Dehydroepiandrosterone 19.7216397352
MESH:D015663 Osteoporosis, Postmenopausal Genistein 19.7216169203
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 19.7219495926
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 19.7217513867
MESH:D010049 Ovarian Diseases bisphenol A 4.4111985600
MESH:D010051 Ovarian Neoplasms 1,3-butadiene 23.262208121
MESH:D010051 Ovarian Neoplasms Benzene 23.2612562636
MESH:D010051 Ovarian Neoplasms Curcumin 23.2619020741 18462866
MESH:D010051 Ovarian Neoplasms Estradiol 23.2619401270
MESH:D010051 Ovarian Neoplasms Genistein 23.2619005980
MESH:D010051 Ovarian Neoplasms Quercetin 23.2619005980
MESH:D010051 Ovarian Neoplasms sodium arsenite 23.2615276417 17306315
MESH:D010051 Ovarian Neoplasms Urethane 23.2616391232
MESH:D010146 Pain Acetaminophen 5.3816870215
MESH:D010146 Pain Sulindac 5.383291741
MESH:D010190 Pancreatic Neoplasms marker/mechanism 14520703 19424582
MESH:D010190 Pancreatic Neoplasms 2,2-bis(bromomethyl)-1,3-propanediol 25.079437797
MESH:D010190 Pancreatic Neoplasms 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 25.0712384795
MESH:D010190 Pancreatic Neoplasms Curcumin 25.0719401701 17440100 19196508
MESH:D010190 Pancreatic Neoplasms Fluorouracil 25.0719003803 16929163 16500647 15113037
MESH:D010190 Pancreatic Neoplasms Methylnitrosourea 25.0716965848
MESH:D010190 Pancreatic Neoplasms Quercetin 25.0716965848
MESH:D010190 Pancreatic Neoplasms Sulindac 25.0716820089 11504793
MESH:D010190 Pancreatic Neoplasms Tetradecanoylphorbol Acetate 25.0715976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.1611578682
MESH:D010212 Papilloma Tetradecanoylphorbol Acetate 3.748330346 18404319 12065085 18922899
MESH:D010300 Parkinson Disease Polychlorinated Biphenyls 3.1616702228
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.6612520081
MESH:D010538 Peritonitis Ozone 3.5716369182
MESH:D010911 Pituitary Neoplasms Urethane 4.8516391232
MESH:D011014 Pneumonia Ozone 3.8218929643 18007984 18381685
MESH:D017285 Polymyositis Vinyl Chloride 6.2811642524
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.0118163543
MESH:D011230 Precancerous Conditions Quercetin 3.4919056647
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 12.9810548101
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 12.9816679765
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 12.9811896295 11118676 11399792 11222880
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 8.8320887781
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 8.8320887781
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 3.8117292933
MESH:D011471 Prostatic Neoplasms bisphenol A 3.8116740699
MESH:D011471 Prostatic Neoplasms Curcumin 3.8111398177 18156803 12497104 10851300 18769126 15129424 18226269
MESH:D011471 Prostatic Neoplasms Estradiol 3.8116740699
MESH:D011471 Prostatic Neoplasms Fluorouracil 3.8118626508 19082440
MESH:D011471 Prostatic Neoplasms Genistein 3.8115378649 16925846 15256057
MESH:D011471 Prostatic Neoplasms Methylnitrosourea 3.8112376480 15682402
MESH:D011471 Prostatic Neoplasms Polychlorinated Biphenyls 3.8115721890
MESH:D011471 Prostatic Neoplasms Quercetin 3.8114715546 17292933
MESH:D011471 Prostatic Neoplasms resveratrol 3.8116731767 17804756 17718901 17636462 15767336 17675339
MESH:D011471 Prostatic Neoplasms sodium arsenite 3.8116039940
MESH:D011537 Pruritus Ethinyl Estradiol 2.7416919318 15861022
MESH:D011595 Psychomotor Agitation Haloperidol 4.3911575062
MESH:D011618 Psychotic Disorders Haloperidol 3.8311575062
MESH:D011629 Puberty, Precocious bisphenol A 4.2110548101
MESH:D011656 Pulmonary Emphysema Curcumin 4.0219168576
MESH:D011928 Raynaud Disease Vinyl Chloride 5.5716977343
MESH:D012004 Rectal Neoplasms Fluorouracil 3.5216160472 15538739 18286688 18722050
MESH:D012021 Reflex, Abnormal Pentobarbital 5.4510930210
MESH:D051436 Renal Insufficiency, Chronic resveratrol 5.0016325855
MESH:D015427 Reperfusion Injury pirinixic acid 5.5319058328
MESH:D015427 Reperfusion Injury resveratrol 5.5317058453 16314181 17520802 15827377 16317513
MESH:D012120 Respiration Disorders Chlorine 4.6318579056
MESH:D012128 Respiratory Distress Syndrome, Adult Curcumin 3.5018379247 10666014
MESH:D012135 Respiratory Sounds Tobacco Smoke Pollution 4.0718410779
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.2918990726
MESH:D012162 Retinal Degeneration Methylnitrosourea 3.9718172121 18155124
MESH:D012175 Retinoblastoma Methylnitrosourea 4.9111555667
MESH:D012509 Sarcoma Curcumin 8.4018462866
MESH:D012509 Sarcoma Vinyl Chloride 8.4012828392
MESH:D012554 Schistosomiasis japonica Quercetin 4.9616862918
MESH:D012559 Schizophrenia Haloperidol 2.7219369910 20107430 18513383 1830565
MESH:D012595 Scleroderma, Systemic Vinyl Chloride 5.2714979077
MESH:D012640 Seizures 2,4-dinitrotoluene 14.4118551238
MESH:D012640 Seizures Pentobarbital 14.4110087439 9754883
MESH:D012640 Seizures Picrotoxin 14.418635557 8954991
MESH:D012640 Seizures Secobarbital 14.419806000
MESH:D012640 Seizures Thiamylal 14.419046859
MESH:D018805 Sepsis Curcumin 3.6018389075
MESH:D012878 Skin Neoplasms 2,2-bis(bromomethyl)-1,3-propanediol 26.739437797 12594523
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 26.7310029692 19755658
MESH:D012878 Skin Neoplasms resveratrol 26.738985016 15837718
MESH:D012878 Skin Neoplasms sodium arsenite 26.7319524636 18572023
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 26.7316192470
MESH:D012878 Skin Neoplasms Tetradecanoylphorbol Acetate 26.7318404319 12065085 8330346 11807781 8985016
MESH:D012878 Skin Neoplasms Tobacco Smoke Pollution 26.7318590791
MESH:D012878 Skin Neoplasms Urethane 26.7311807781
MESH:D013088 Spermatocele Ethinyl Estradiol 3.3616709447
MESH:D016135 Spinal Dysraphism sodium arsenite 3.3412854658
MESH:D013158 Splenic Diseases Dimethylnitrosamine 4.6812587719
MESH:D013272 Stomach Diseases rebamipide 4.7016184426
MESH:D013274 Stomach Neoplasms marker/mechanism 11397402
MESH:D013274 Stomach Neoplasms 1,3-butadiene 20.4811397402 2208121
MESH:D013274 Stomach Neoplasms Benzene 20.4812562636
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 20.4820155912 2093021
MESH:D013274 Stomach Neoplasms Chloroprene 20.4811397402 12562636
MESH:D013274 Stomach Neoplasms diisopropanolnitrosamine 20.481399818
MESH:D013274 Stomach Neoplasms Dimethylnitrosamine 20.4816033868
MESH:D013274 Stomach Neoplasms Fluorouracil 20.4817522103 15786421 16424979 18567086 17172411 17498489 19084572 19015929 18396642 16951190
MESH:D013274 Stomach Neoplasms isoprene 20.4812562636 11397402
MESH:D013274 Stomach Neoplasms Methylnitrosourea 20.4816257854 18593901 15930296
MESH:D013274 Stomach Neoplasms rebamipide 20.4815993841
MESH:D013274 Stomach Neoplasms Vinyl Chloride 20.4812562636
MESH:D013274 Stomach Neoplasms Zidovudine 20.4817696246
MESH:D013276 Stomach Ulcer Curcumin 3.0116631530 19188055
OMIM:601367 STROKE, ISCHEMIC resveratrol 3.9816321402
MESH:D019966 Substance-Related Disorders bisphenol A 3.4116684133 16045194
MESH:D013375 Substance Withdrawal Syndrome Pentobarbital 4.4811529278 9754883
MESH:D017180 Tachycardia, Ventricular Haloperidol 4.1620210726
MESH:D013736 Testicular Neoplasms isoprene 5.8812562636
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.0911994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.6715669648
MESH:D013953 Thymus Neoplasms Benzene 17.0310850423
MESH:D013953 Thymus Neoplasms Ethylnitrosourea 17.0315790496
MESH:D013953 Thymus Neoplasms Methylnitrosourea 17.0311418001
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.3212697716
MESH:D013964 Thyroid Neoplasms marker/mechanism 3078959
MESH:D013964 Thyroid Neoplasms 2,2-bis(bromomethyl)-1,3-propanediol 13.839437797 12594523
MESH:D013964 Thyroid Neoplasms Chloroprene 13.8312562636
MESH:D013964 Thyroid Neoplasms diisopropanolnitrosamine 13.836582329 1399818 7505956 3289735
MESH:D013964 Thyroid Neoplasms Methylnitrosourea 13.833078959 7505956
MESH:D013978 Tibial Fractures Estradiol 4.1019048282
MESH:D014062 Tongue Neoplasms Fluorouracil 8.3216280240
MESH:D014062 Tongue Neoplasms resveratrol 8.3216227395
MESH:D001749 Urinary Bladder Neoplasms marker/mechanism
MESH:D001749 Urinary Bladder Neoplasms 2,2-bis(bromomethyl)-1,3-propanediol 23.912731663 9437797 12594523
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 23.9116049721
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 23.9117053015
MESH:D001749 Urinary Bladder Neoplasms Curcumin 23.9118593936
MESH:D001749 Urinary Bladder Neoplasms diisopropanolnitrosamine 23.911399818
MESH:D001749 Urinary Bladder Neoplasms Quercetin 23.9116720314
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 23.9116452187 16712894 11723127 17306315
MESH:D001749 Urinary Bladder Neoplasms Tobacco Smoke Pollution 23.9112846360
MESH:D014565 Urogenital Neoplasms Curcumin 4.6918462866
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 3.7410091137
MESH:D014581 Urticaria Acetaminophen 2.4510982225
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 13.0216803524
MESH:D002583 Uterine Cervical Neoplasms resveratrol 13.0217473185
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 13.0211813266
MESH:D014591 Uterine Diseases bisphenol A 4.4214652134
MESH:D014594 Uterine Neoplasms marker/mechanism 17325976
MESH:D014594 Uterine Neoplasms Benzene 18.4912562636
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 18.4914692618
MESH:D014594 Uterine Neoplasms resveratrol 18.4917044934
MESH:D014594 Uterine Neoplasms Sulindac 18.4918645019
MESH:D014625 Vaginal Neoplasms Zidovudine 4.2012579204
MESH:D014652 Vascular Diseases sodium arsenite 3.8517056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.0112125929
MESH:D019043 Vascular Neoplasms Urethane 5.3310620525
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.0214671159 15869587
MESH:D018487 Ventricular Dysfunction, Left resveratrol 3.7417488730
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.6615886252
Pathway ID Pathway Name
KEGG:05221 Acute myeloid leukemia
KEGG:04960 Aldosterone-regulated sodium reabsorption
KEGG:04360 Axon guidance
REACT:18266 Axon guidance
KEGG:04662 B cell receptor signaling pathway
KEGG:05219 Bladder cancer
KEGG:04062 Chemokine signaling pathway
KEGG:05220 Chronic myeloid leukemia
KEGG:05210 Colorectal cancer
KEGG:04320 Dorso-ventral axis formation
KEGG:04144 Endocytosis
KEGG:05213 Endometrial cancer
KEGG:04012 ErbB signaling pathway
KEGG:04664 Fc epsilon RI signaling pathway
KEGG:04510 Focal adhesion
KEGG:04540 Gap junction
KEGG:05214 Glioma
KEGG:04912 GnRH signaling pathway
REACT:604 Hemostasis
KEGG:05160 Hepatitis C
KEGG:04910 Insulin signaling pathway
KEGG:04730 Long-term depression
KEGG:04720 Long-term potentiation
KEGG:04010 MAPK signaling pathway
KEGG:04916 Melanogenesis
KEGG:05218 Melanoma
KEGG:04650 Natural killer cell mediated cytotoxicity
KEGG:04722 Neurotrophin signaling pathway
KEGG:05223 Non-small cell lung cancer
KEGG:05212 Pancreatic cancer
KEGG:05200 Pathways in cancer
KEGG:04914 Progesterone-mediated oocyte maturation
KEGG:05215 Prostate cancer
KEGG:04810 Regulation of actin cytoskeleton
KEGG:05211 Renal cell carcinoma
REACT:9417 Signaling by EGFR
REACT:498 Signaling by Insulin receptor
REACT:16888 Signaling by PDGF
REACT:6900 Signaling in Immune system
REACT:11061 Signalling by NGF
KEGG:04660 T cell receptor signaling pathway
KEGG:05216 Thyroid cancer
KEGG:04530 Tight junction
KEGG:04370 VEGF signaling pathway
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA30196
    • Releated gene ID Related gene Name
    PA34321REL
    PA36348TBK1
    PA248NFKB1
    PA34198RALB
    PA76BCL2L1
    Releated disease ID Related disease Name
    PA445218Pancreatic Neoplasms
    PA446108Colorectal Neoplasms
    PA444818Lung Neoplasms
    PA152208657Cardio-facio-cutaneous Syndrome
    PA445123Noonan Syndrome
    PA445062Neoplasms
    PA443756Colonic Neoplasms
    Releated drug ID Related drug Name
    PA450085irinotecan
    PA451581tamoxifen
    PA10040cetuximab
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB07752 - FARNESYL
    DB07771 - [(3,7,11-TRIMETHYL-DODECA-2,6,10-TRIENYLOXYCARBAMOYL)-METHYL]-PHOSPHONIC ACID
    DB07780 - FARNESYL DIPHOSPHATE
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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