AutismKB 2.0

Annotation Detail for KRT7


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Basic Information Top
Gene Symbol:KRT7 ( CK7,K2C7,K7,MGC129731,MGC3625,SCL )
Gene Full Name: keratin 7
Band: 12q13.13
Quick LinksEntrez ID:3855; OMIM: 148059; Uniprot ID:K2C7_HUMAN; ENSEMBL ID: ENSG00000135480; HGNC ID: 6445
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1934Cancer
1940Ovarian disease
2094Ulcerative colitis
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C010914 2,4-diaminotoluene 2,4-diaminotoluene results in increased expression of KRT7 mRNAincreases expression 20713471
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in decreased expression of KRT7 mRNAdecreases expression 18648102
C002202 4-oxoretinoic acid 4-oxoretinoic acid results in increased expression of KRT7 mRNAincreases expression 15982314
17034753
C002202 4-oxoretinoic acid 4-oxoretinoic acid results in increased expression of KRT7 proteinincreases expression 15982314
C041819 4-oxoretinol 4-oxoretinol results in increased expression of KRT7 mRNAincreases expression 17034753
C103303 alitretinoin alitretinoin results in increased expression of KRT7 mRNAincreases expression 15982314
17034753
C103303 alitretinoin alitretinoin results in increased expression of KRT7 proteinincreases expression 15982314
D000643 Ammonium Chloride Ammonium Chloride results in increased expression of KRT7 proteinincreases expression 16483693
C004984 apocarotenal apocarotenal affects the expression of KRT7 mRNAaffects expression 17034753
C015001 arsenite arsenite results in decreased expression of KRT7 mRNAdecreases expression 19716837
C015001 arsenite arsenite results in increased methylation of KRT7 promoterincreases methylation 19716837
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of KRT7 mRNAincreases expression 19150397
D019207 beta Carotene beta Carotene affects the expression of KRT7 mRNAaffects expression 17034753
D002104 Cadmium Cadmium results in decreased expression of KRT7 mRNAdecreases expression 19716837
D002104 Cadmium Cadmium results in increased methylation of KRT7 promoterincreases methylation 19716837
D019259 Lamivudine [Zidovudine co-treated with Lamivudine] results in increased expression of KRT7 mRNAaffects cotreatment|increases expression 15784690
D004391 Dust Dust results in decreased expression of KRT7 mRNAdecreases expression 17805423
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of KRT7 mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of KRT7 mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of KRT7 mRNAaffects cotreatment|increases expression 17942748
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of KRT7 mRNAincreases expression 17557909
D015025 Zearalenone Zearalenone results in increased expression of KRT7 mRNAincreases expression 17557909
C011890 kojic acid kojic acid results in increased expression of KRT7 mRNAincreases expression 16595896
C406082 monomethylarsonous acid [monomethylarsonous acid affects the acetylation of HIST3H3 protein] which affects the methylation of KRT7 promoteraffects acetylation|affects methylation 18448484
C406082 monomethylarsonous acid monomethylarsonous acid results in decreased expression of KRT7 mRNAdecreases expression 20375083
19716837
C406082 monomethylarsonous acid monomethylarsonous acid results in increased methylation of KRT7 promoterincreases methylation 19716837
20375083
C029938 nickel sulfate nickel sulfate affects the expression of KRT7 mRNAaffects expression 12718980
D017239 Paclitaxel KRT7 protein results in increased susceptibility to Paclitaxelincreases response to substance 16734730
D015474 Isotretinoin Isotretinoin results in increased expression of KRT7 mRNAincreases expression 15982314
D015474 Isotretinoin Isotretinoin results in increased expression of KRT7 proteinincreases expression 15982314
D012643 Selenium Selenium results in increased expression of KRT7 mRNAincreases expression 19244175
C017947 sodium arsenite [sodium arsenite affects the acetylation of HIST3H3 protein] which affects the methylation of KRT7 promoteraffects acetylation|affects methylation 18448484
C017947 sodium arsenite sodium arsenite results in increased expression of KRT7 mRNAincreases expression 19524636
C017947 sodium arsenite sodium arsenite results in increased expression of KRT7 proteinincreases expression 19524636
D013629 Tamoxifen Tamoxifen affects the expression of KRT7 mRNAaffects expression 17555576
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of KRT7 mRNAaffects cotreatment|increases expression 17942748
D014212 Tretinoin Tretinoin metabolite results in increased expression of KRT7 mRNAincreases expression 15982314
D014212 Tretinoin Tretinoin metabolite results in increased expression of KRT7 proteinincreases expression 15982314
D014212 Tretinoin Tretinoin results in increased expression of KRT7 mRNAincreases expression 17034753
15982314
D014212 Tretinoin Tretinoin results in increased expression of KRT7 proteinincreases expression 15982314
C025643 vinclozolin vinclozolin affects the expression of KRT7 mRNAaffects expression 19015723
D014801 Vitamin A Vitamin A results in increased expression of KRT7 mRNAincreases expression 17034753
D015215 Zidovudine [Zidovudine co-treated with Lamivudine] results in increased expression of KRT7 mRNAaffects cotreatment|increases expression 15784690
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.3014745880
MESH:D000014 Abnormalities, Drug-Induced Isotretinoin 7.8818769834
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 7.8814514962 15322242 11752688
MESH:D000015 Abnormalities, Multiple Isotretinoin 10.0318769834
MESH:D000015 Abnormalities, Multiple Vitamin A 10.0310992263
MESH:D000138 Acidosis Ammonium Chloride 3.3118287403
MESH:D017486 Acneiform Eruptions Isotretinoin 6.0316232082
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 11.1617505938
MESH:D000152 Acne Vulgaris Isotretinoin 11.1618769834 16185265
MESH:D000163 Acquired Immunodeficiency Syndrome Zidovudine 4.589612607
MESH:D055371 Acute Lung Injury nickel sulfate 4.0816100012 19131640 12718980 11954676
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.7514692618
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 2.613712494
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 3.1316835633
MESH:D018249 Adenoma, Oxyphilic marker/mechanism 16927643
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.4515276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.6517306315 16712894
MESH:D000505 Alopecia Tretinoin 3.4215955085
MESH:D000740 Anemia Tetrachlorodibenzodioxin 8.2711748828
MESH:D000740 Anemia Vitamin A 8.2716960172
MESH:D018798 Anemia, Iron-Deficiency Vitamin A 4.5816960172
MESH:D001008 Anxiety Disorders vinclozolin 3.4519015723
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.2211256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 6.7115885639
MESH:D001169 Arthritis, Experimental Tretinoin 6.7116412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.2116292516
MESH:D001249 Asthma Tretinoin 4.9616456186
MESH:D001249 Asthma Vitamin A 4.9616732791
MESH:D050197 Atherosclerosis Cadmium 3.5015687053
MESH:D001471 Barrett Esophagus Tretinoin 4.1716935849
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.771440618 11289319
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 8.2112125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 8.2116206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.5415340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.6115746008
MESH:D001859 Bone Neoplasms Paclitaxel 4.3415867366
MESH:D002545 Brain Ischemia beta Carotene 4.8516157235
MESH:D001943 Breast Neoplasms 2,4-diaminotoluene 2.8511921183
MESH:D001943 Breast Neoplasms alitretinoin 2.8516344269
MESH:D001943 Breast Neoplasms Paclitaxel 2.8518223236 16244791 18234424 15136595 11325840 16273361 16115903 18323546
MESH:D001943 Breast Neoplasms Tamoxifen 2.8517049068 17893378 20005174 19155303 17440819 18855134 19410462 19221464 19115204 19011961 20390343 16202921 19066611 19189212 18821012 18351453 19487384 19244106 18997820 19142967 17261762 20135344 21152245 18815881 17242785 19084267 19200415 11161223 21138602 15565566 20065188 15668708 19289846 20544844 18425577 18629630 16818667 19189210 19288272 16273361 16873071 19059307 19103187 20859285 18984771
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.8520435547
MESH:D001943 Breast Neoplasms Tretinoin 2.8516873071 16443354 16166294
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 12.2016813970
MESH:D001997 Bronchopulmonary Dysplasia Vitamin A 12.2017377406 17426644
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.6116835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.2619066611
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.9116168501
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 8.433581430 7296757
MESH:D006528 Carcinoma, Hepatocellular Paclitaxel 8.4316313753
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 8.4317306315 15276417 16507464
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 8.4316924424
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 8.431917145
MESH:D002292 Carcinoma, Renal Cell marker/mechanism 16927643
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.567296757
MESH:D002294 Carcinoma, Squamous Cell Isotretinoin 7.2611237771
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 7.2618572023
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 7.2616096774 16051514
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.4017572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.2318850075 18670907 16120746
MESH:D002386 Cataract Tretinoin 2.9517460283
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 19.357505956
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 19.3520889678
MESH:D002471 Cell Transformation, Neoplastic Cadmium 19.3517332340
MESH:D002471 Cell Transformation, Neoplastic monomethylarsonous acid 19.3519716837
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 19.3520056578 19524636
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.3416129372
MESH:D015362 Child Nutrition Disorders Vitamin A 5.2316153327
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 2.9616835633
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 12.539022650 19486331
MESH:D002779 Cholestasis Ethinyl Estradiol 12.5317333356 17681005 11677210 16919318 15861022 16105132 17110522
MESH:D002779 Cholestasis Vitamin A 12.5316175620
MESH:D002822 Choriocarcinoma Tretinoin 4.9116461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 9.3116354765 8697196 12621046 15340226 15668235
MESH:D002972 Cleft Palate Tretinoin 9.319407595
MESH:D002972 Cleft Palate Vitamin A 9.3116054864
MESH:D003092 Colitis Selenium 8.6917936198
MESH:D003092 Colitis Tretinoin 8.6917035595
MESH:D003110 Colonic Neoplasms arsenite 4.1015037631
MESH:D003110 Colonic Neoplasms Vitamin A 4.1017219422 16267017
MESH:D015179 Colorectal Neoplasms Paclitaxel 2.4418802399
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.8514669216 17141729
MESH:D019465 Craniofacial Abnormalities Isotretinoin 5.269879862 18769834
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 5.2620055451 15322242 10048152
MESH:D019465 Craniofacial Abnormalities Tretinoin 5.2617551590 9125849 10589399 8800419 16925845 14991402 9142499 9211117 9224671 9664655
MESH:D019465 Craniofacial Abnormalities Vitamin A 5.2610992263
MESH:D003456 Cryptorchidism vinclozolin 4.1114966744
MESH:D003711 Demyelinating Diseases Tamoxifen 4.1219031437
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 6.358156756 8970840 18759878 11298694 12868966 2524372 14531868 11906362
MESH:D017449 Dermatitis, Allergic Contact nickel sulfate 6.3516823706 16780908 11298694
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.263621924 2952479
MESH:D003922 Diabetes Mellitus, Type 1 Vitamin A 3.4316506275
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.6117107852
MESH:D003928 Diabetic Nephropathies Tamoxifen 3.2719279558
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 5.7518692083 18648102 16192314 9328219 18289764 6482804 9653073 9022650 7440962 1440618 6679447 8291058 11289319
MESH:D056486 Drug-Induced Liver Injury Selenium 5.7515131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 5.7520420201
MESH:D004362 Drug Toxicity Lamivudine 12.8415040536
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 12.8411462148
MESH:D004362 Drug Toxicity Zidovudine 12.8415040536
MESH:D015352 Dry Eye Syndromes Vitamin A 5.5516146918
MESH:C538011 Eales disease Vitamin A 5.379068938
MESH:D004480 Ectromelia Vitamin A 5.5716054864
MESH:D004487 Edema Tetrachlorodibenzodioxin 2.1711000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 11.1118230668 15322242 16714409
MESH:D004489 Edema, Cardiac Tretinoin 11.1118230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 8.1712538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 8.1719031437
MESH:D016889 Endometrial Neoplasms Tamoxifen 6.9117893378 20544844 16202921 19155303
MESH:D016889 Endometrial Neoplasms Tretinoin 6.9116569247
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.8110568697 9294722
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 6.913581430
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 6.9120426865
MESH:D004938 Esophageal Neoplasms Paclitaxel 6.9116481741
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 8.2411564622
MESH:D005124 Eye Abnormalities Tretinoin 8.2416938888 9664655
MESH:D005234 Fatty Liver arsenite 17.0218296743
MESH:D005234 Fatty Liver Ethinyl Estradiol 17.0215345470
MESH:D005234 Fatty Liver Tamoxifen 17.0219224547 14986274
MESH:D005234 Fatty Liver Zidovudine 17.0218299183
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.0916709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.2111858732
MESH:D005327 Fetal Resorption Vitamin A 5.1216054864
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.776705139
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.2814745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 3.9419069698
MESH:D005355 Fibrosis arsenite 13.4418296743
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 13.4420067830
MESH:D005355 Fibrosis Tretinoin 13.4417994277
MESH:D030342 Genetic Diseases, Inborn vinclozolin 4.6916973722
MESH:D005832 Genital Diseases, Male vinclozolin 5.0516417039
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.4316452187
MESH:D005909 Glioblastoma Tretinoin 2.8517312396
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 3.817505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.3410696789
MESH:D006258 Head and Neck Neoplasms Tretinoin 3.0216096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.9116084493
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 10.5110048152 11294989
MESH:D006330 Heart Defects, Congenital Tretinoin 10.519664655 14991402
MESH:D006330 Heart Defects, Congenital Vitamin A 10.5110992263 16080930
MESH:D006333 Heart Failure Selenium 2.9317162251
MESH:D006402 Hematologic Diseases Zidovudine 4.4812579204
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.1211000095
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 3.286705139
MESH:D006509 Hepatitis B Lamivudine 4.8817703166
MESH:D019694 Hepatitis B, Chronic Lamivudine 4.8812044531 15631357 15274664 16476009 15309715
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 2.6516120746 15340226 12621046
MESH:D006548 Hernia, Diaphragmatic Vitamin A 3.5316490937 15707848 16292552 16877224 17436238 16863852
MESH:D015658 HIV Infections beta Carotene 14.4416960176
MESH:D015658 HIV Infections Lamivudine 14.4417530837 11141242 9296927 20032539
MESH:D015658 HIV Infections Vitamin A 14.4416960176
MESH:D015658 HIV Infections Zidovudine 14.4411698656 17358032 20032539 11363243 11141242
MESH:D006679 HIV Seropositivity Vitamin A 5.3517209195
MESH:D006689 Hodgkin Disease sodium arsenite 2.9512676792
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.8018606429 8697196 16959395 16354765 15340226
MESH:D006930 Hyperalgesia Tretinoin 3.0216870215
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.3316778211
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.7015034207
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 1.8218850075 18670907
MESH:D006986 Hypervitaminosis A Vitamin A 5.9216054864
MESH:D007021 Hypospadias Ethinyl Estradiol 3.5716945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.2312013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 10.2717937319
MESH:D007248 Infertility, Male sodium arsenite 10.2712646999 15346721
MESH:D007248 Infertility, Male vinclozolin 10.2716467254
MESH:D007249 Inflammation Tamoxifen 4.4719457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 4.4712200463 12878042
MESH:D007251 Influenza, Human Selenium 3.9516624496
MESH:D007410 Intestinal Diseases Tretinoin 3.5317994277
MESH:D019586 Intracranial Hypertension Vitamin A 5.5715955940
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.778074119 9022650
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 9.2016580747
MESH:D007569 Jaw Abnormalities Tretinoin 9.2015992940 17551590
MESH:D017492 Keratosis, Seborrheic alitretinoin 5.3916144296
MESH:D007674 Kidney Diseases Cadmium 5.9816322080 16962696 16226777
MESH:D007674 Kidney Diseases sodium arsenite 5.9820008137
MESH:D007676 Kidney Failure, Chronic Selenium 3.6716518626
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 11.376582329
MESH:D007680 Kidney Neoplasms Tamoxifen 11.3718625569
MESH:D007680 Kidney Neoplasms Zidovudine 11.3712579204
MESH:D007938 Leukemia Tretinoin 2.6517143497
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Zidovudine 4.1920370541
MESH:D007951 Leukemia, Myeloid Tretinoin 3.4819285840 16482212 16932348
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 2.0417596541 16294345 19850784
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 2.9912679006 19035177 19029980 16823087 17301526 17294898 16140955 9834237 16935935 17649720 19225113 17107899 17506722 16891316 17368321 17712046 17217047 16788101 19642359 15748426 16331271 17361223 16766008 17339181 19075265
MESH:D007984 Leydig Cell Tumor vinclozolin 4.4816417039
MESH:D017880 Limb Deformities, Congenital Tretinoin 7.929224671
MESH:D017880 Limb Deformities, Congenital Vitamin A 7.9216054864
MESH:D008064 Lipidoses Tamoxifen 2.9815342952 17567588
MESH:D008080 Liposarcoma Paclitaxel 4.5917353645
MESH:D008103 Liver Cirrhosis arsenite 6.7718296743
MESH:D008103 Liver Cirrhosis Vitamin A 6.7716256175
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.0415034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 4.7418564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 4.7412878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 4.7418397230 16248980
MESH:D008106 Liver Cirrhosis, Experimental Vitamin A 4.7416248980
MESH:D008107 Liver Diseases Vitamin A 3.0916175620
MESH:D008108 Liver Diseases, Alcoholic Vitamin A 4.9116762690
MESH:D008113 Liver Neoplasms sodium arsenite 6.8616712894 15276417
MESH:D008113 Liver Neoplasms Tamoxifen 6.8616684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 6.8616984957
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 17.08598648 1399818 3712494 6587162
MESH:D008114 Liver Neoplasms, Experimental beta Carotene 17.0817113696
MESH:D008114 Liver Neoplasms, Experimental kojic acid 17.0818544905
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 17.0812151625
MESH:D008114 Liver Neoplasms, Experimental Vitamin A 17.0817113696
MESH:D008171 Lung Diseases sodium arsenite 7.2419095001
MESH:D008171 Lung Diseases Vitamin A 7.2416863852
MESH:D008175 Lung Neoplasms alitretinoin 12.4416413115
MESH:D008175 Lung Neoplasms arsenite 12.4416809336
MESH:D008175 Lung Neoplasms beta Carotene 12.4416401635
MESH:D008175 Lung Neoplasms Isotretinoin 12.4415899809
MESH:D008175 Lung Neoplasms sodium arsenite 12.4417077188 16712894 15276417 17306315 19931552
MESH:D008175 Lung Neoplasms Tamoxifen 12.4418625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 12.4411884234 19555203
MESH:D008175 Lung Neoplasms Zidovudine 12.4418800350
MESH:D008228 Lymphoma, Non-Hodgkin Paclitaxel 3.8914749477
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.5119428831
MESH:D008325 Mammary Neoplasms, Experimental 2,4-diaminotoluene 9.1911921183
MESH:D008325 Mammary Neoplasms, Experimental Selenium 9.1915318939
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 9.1914580682 16827153 11731420 19196722 19196723
MESH:D020149 Manganese Poisoning Tamoxifen 4.3019453300
MESH:D008527 Medulloblastoma Tretinoin 2.6917453147
MESH:D008545 Melanoma Isotretinoin 9.3217237267
MESH:D008545 Melanoma Paclitaxel 9.3212025231 16342250 12040289
MESH:D008545 Melanoma sodium arsenite 9.3219082730 16487513
MESH:D008545 Melanoma Tamoxifen 9.3219393235 12393984
MESH:D008545 Melanoma Tretinoin 9.3216752155
MESH:D018328 Melanoma, Amelanotic Tamoxifen 3.9415990972
MESH:D008591 Meningomyelocele Tretinoin 4.1816940565
MESH:D008654 Mesothelioma Selenium 2.6915107826
MESH:D048629 Micronuclei, Chromosome-Defective Zidovudine 5.5917358032
MESH:D009101 Multiple Myeloma Paclitaxel 7.2814749477
MESH:D009101 Multiple Myeloma Vitamin A 7.2816374440
MESH:D009190 Myelodysplastic Syndromes Tretinoin 2.9417596541
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.8312213967
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 8.983581430
MESH:D009362 Neoplasm Metastasis Paclitaxel 8.9815867366
MESH:D009362 Neoplasm Metastasis Tamoxifen 8.9819393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.4419410462
MESH:D009369 Neoplasms alitretinoin 10.9716946489
MESH:D009369 Neoplasms beta Carotene 10.9717051425
MESH:D009369 Neoplasms sodium arsenite 10.9711559025
MESH:D009369 Neoplasms Tretinoin 10.9716594593 16946489
MESH:D009374 Neoplasms, Experimental sodium arsenite 3.4320056578
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.7519200415 19189210 19196722
MESH:D009389 Neovascularization, Pathologic arsenite 4.1715738583
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 8.7314600291
MESH:D009421 Nervous System Malformations Tretinoin 8.739125849
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 16.076679447
MESH:D009436 Neural Tube Defects sodium arsenite 16.0712854658
MESH:D009436 Neural Tube Defects Tretinoin 16.079142499
MESH:D009436 Neural Tube Defects Vitamin A 16.0717400914
MESH:D009447 Neuroblastoma Isotretinoin 3.9217368321
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.214026338 6482804
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.773988306
MESH:D010014 Osteolysis Paclitaxel 4.7315867366
MESH:D010051 Ovarian Neoplasms Paclitaxel 7.5111161223
MESH:D010051 Ovarian Neoplasms sodium arsenite 7.5115276417 17306315
MESH:D010051 Ovarian Neoplasms Tretinoin 7.5116936753
MESH:D010146 Pain Tretinoin 2.7116870215
MESH:D010190 Pancreatic Neoplasms Tretinoin 2.3815976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.4611578682
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.247296757
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.0012520081
MESH:D016491 Peripheral Vascular Diseases Cadmium 5.1415687053
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.226228378
MESH:D010954 Plasmacytoma Selenium 4.6415087411
MESH:D017499 Porokeratosis alitretinoin 5.7516144296
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.3218163543
MESH:D011297 Prenatal Exposure Delayed Effects Isotretinoin 14.9518769834
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 14.9511118676 11222880 11399792 11896295
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 14.9519015723 18220299 18042343
MESH:D011469 Prostatic Diseases vinclozolin 4.6918220299
MESH:D011471 Prostatic Neoplasms Cadmium 2.1917075824
MESH:D011471 Prostatic Neoplasms Paclitaxel 2.1917172428 17136230 16356831 16729912
MESH:D011471 Prostatic Neoplasms sodium arsenite 2.1916039940
MESH:D011471 Prostatic Neoplasms Tamoxifen 2.1915067354
MESH:D011472 Prostatitis vinclozolin 4.6918629315
MESH:D011507 Proteinuria Tretinoin 3.3816636307
MESH:D011537 Pruritus Ethinyl Estradiol 3.0715861022 16919318
MESH:D011596 Psychomotor Disorders Isotretinoin 5.6718769834
MESH:D011625 Pterygium Tretinoin 4.5516723453
MESH:D012127 Respiratory Distress Syndrome, Newborn Vitamin A 5.5516877224
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.6018990726
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.193692021
MESH:D012206 Rhabdomyolysis Lamivudine 5.299296927
MESH:D012208 Rhabdomyosarcoma Tretinoin 3.8716283617 16116481
MESH:D012871 Skin Diseases monomethylarsonous acid 5.3917431481
MESH:D012871 Skin Diseases Vitamin A 5.3918709164
MESH:D012878 Skin Neoplasms sodium arsenite 8.7519524636 18572023
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 8.7516192470
MESH:D012878 Skin Neoplasms Tretinoin 8.7516467112
MESH:D013088 Spermatocele Ethinyl Estradiol 10.7316709447
MESH:D013088 Spermatocele Tamoxifen 10.7316709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.7919457130
MESH:D016135 Spinal Dysraphism sodium arsenite 3.6112854658
MESH:D013272 Stomach Diseases beta Carotene 4.8517638125
MESH:D013274 Stomach Neoplasms Paclitaxel 3.4118396642 18506536
MESH:D013274 Stomach Neoplasms Tretinoin 3.4117261132
MESH:D013274 Stomach Neoplasms Zidovudine 3.4117696246
MESH:D013276 Stomach Ulcer beta Carotene 4.0412500499
MESH:D024801 Tauopathies Paclitaxel 4.5716930453
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.3911994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.9515669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.6512697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 6.526587162 6582329 1399818 7505956 3712494
MESH:D013964 Thyroid Neoplasms Tretinoin 6.5217045167 16026305
MESH:D014062 Tongue Neoplasms Tretinoin 3.5716051514
MESH:D014376 Tuberculosis Tretinoin 3.0816040207
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 11.178074119
MESH:D001749 Urinary Bladder Neoplasms monomethylarsonous acid 11.1720375083
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 11.1716712894 16452187 17306315 11723127
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 11.1716712894 17572228 8653321
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 8.7011813266
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 8.7016129372
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.0614692618
MESH:D014604 Uveal Neoplasms Tretinoin 4.3616752155
MESH:D014625 Vaginal Neoplasms Zidovudine 4.5212579204
MESH:D014652 Vascular Diseases sodium arsenite 4.1817056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.3412125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.3214671159 15869587
MESH:D014802 Vitamin A Deficiency Vitamin A 5.0516175781 16960172 16146918
MESH:D014820 Vitiligo Tretinoin 3.8216761959
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.0015886252
MESH:D009396 Wilms Tumor Tretinoin 3.7616287080
No data
Pharmacogenomics Knowledge Base Top
Drug Bank Top
Drugbank ID Action Drug Name Description
DB01087 other/unknown Primaquine Antimalarials;Antiprotozoal Agents;Antimalarial Agents
No data
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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