AutismKB 2.0

Annotation Detail for KRT18


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Basic Information Top
Gene Symbol:KRT18 ( CYK18,K18 )
Gene Full Name: keratin 18
Band: 12q13.13
Quick LinksEntrez ID:3875; OMIM: 148070; Uniprot ID:K1C18_HUMAN; ENSEMBL ID: ENSG00000111057; HGNC ID: 6430
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa05130Pathogenic Escherichia coli infection
No data
Pathway IDPathway Name
200148Caspase cascade in apoptosis
No data
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1717Cholangitis
1848Embryoma
1943Adenocarcinoma
1944Breast cancer
1976Squamous cell cancer
2008Liver disease
2061Epidermolysis bullosa
2100Hepatitis C
2233Cirrhosis
No data
No data
Desease Name
Cirrhosis, noncryptogenic, susceptibility to
Cirrhosis, cryptogenic
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of KRT18 mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of KRT18 mRNAaffects expression 21346803
C496751 4-(1H-imidazol-1-yl)retinoic acid 4-(1H-imidazol-1-yl)retinoic acid results in increased expression of KRT18 proteinincreases expression 17145897
17387344
C496751 4-(1H-imidazol-1-yl)retinoic acid 4-(1H-imidazol-1-yl)retinoic acid results in increased expression of KRT18 proteinincreases expression 17145897
C035207 4-amino-2,6-dinitrotoluene 4-amino-2,6-dinitrotoluene affects the expression of KRT18 mRNAaffects expression 21346803
C002202 4-oxoretinoic acid 4-oxoretinoic acid results in increased expression of KRT18 mRNAincreases expression 17034753
C041819 4-oxoretinol 4-oxoretinol results in increased expression of KRT18 mRNAincreases expression 17034753
C501332 ABT-737 ABT-737 results in increased cleavage of KRT18 proteinincreases cleavage 19010845
D000082 Acetaminophen Acetaminophen affects the expression of KRT18 mRNAaffects expression 17562736
C103303 alitretinoin alitretinoin results in increased expression of KRT18 mRNAincreases expression 17034753
D000643 Ammonium Chloride Ammonium Chloride affects the expression of KRT18 mRNAaffects expression 16483693
D000643 Ammonium Chloride Ammonium Chloride affects the expression of KRT18 proteinaffects expression 16483693
D016718 Arachidonic Acid [[Arachidonic Acid co-treated with ferric nitrilotriacetate co-treated with Ethanol] results in increased expression of CYP2E1 protein] which results in increased expression of KRT18 proteinaffects cotreatment|increases expression 17034788
D001151 Arsenic Arsenic results in decreased expression of KRT18 mRNAdecreases expression 12773770
11134558
C006632 arsenic trioxide arsenic trioxide results in increased expression of KRT18 mRNAincreases expression 15073043
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of KRT18 mRNAincreases expression 20064835
D019207 beta Carotene beta Carotene results in increased expression of KRT18 mRNAincreases expression 17034753
D002101 Cacodylic Acid Cacodylic Acid results in decreased expression of KRT18 mRNAdecreases expression 17481689
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of KRT18 mRNAaffects expression 17484886
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of KRT18 mRNAincreases expression 17522070
D002725 Chloroform Chloroform results in increased expression of KRT18 mRNAincreases expression 17522070
D002994 Clofibrate Clofibrate results in decreased expression of KRT18 mRNAdecreases expression 17522070
C057862 cyanoginosin LR cyanoginosin LR results in increased expression of KRT18 mRNAincreases expression 17654400
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with Piperonyl Butoxide] results in increased expression of KRT18 proteinaffects cotreatment|increases expression 20101389
D004052 Diethylnitrosamine [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of KRT18 proteinaffects cotreatment|increases expression 18978307
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of KRT18 mRNAaffects cotreatment|increases expression 19409407
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of KRT18 proteinaffects cotreatment|increases expression 19409407
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of KRT18 proteinincreases expression 20935162
D004052 Diethylnitrosamine [Phenobarbital co-treated with Diethylnitrosamine] results in increased expression of KRT18 proteinaffects cotreatment|increases expression 20935162
D004054 Diethylstilbestrol Diethylstilbestrol results in decreased expression of KRT18 mRNAdecreases expression 15171707
C444299 diindolylmethane diindolylmethane inhibits the reaction [Estradiol results in increased expression of KRT18 mRNA]decreases reaction|increases expression 11179685
D004112 Dimercaprol Dimercaprol inhibits the reaction [Mustard Gas results in increased expression of KRT18 mRNA]decreases reaction|increases expression 16377760
D004128 Dimethylnitrosamine Dimethylnitrosamine results in increased expression of KRT18 mRNAincreases expression 17072980
D004317 Doxorubicin KRT18 protein affects the susceptibility to Doxorubicinaffects response to substance 16928833
D004918 Erythromycin Estolate Erythromycin Estolate results in increased expression of KRT18 mRNAincreases expression 17522070
D004958 Estradiol diindolylmethane inhibits the reaction [Estradiol results in increased expression of KRT18 mRNA]decreases reaction|increases expression 11179685
D004958 Estradiol Estradiol results in increased expression of KRT18 mRNAincreases expression 11179685
D004958 Estradiol KRT18 protein promotes the reaction [fulvestrant inhibits the reaction [Estradiol results in increased activity of ESR1 protein]]decreases reaction|increases activity|increases reaction 20061804
D004958 Estradiol Tetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased expression of KRT18 mRNA]decreases reaction|increases expression 11179685
D000431 Ethanol [[Arachidonic Acid co-treated with ferric nitrilotriacetate co-treated with Ethanol] results in increased expression of CYP2E1 protein] which results in increased expression of KRT18 proteinaffects cotreatment|increases expression 17034788
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of KRT18 mRNAincreases expression 12655037
C052498 FEC protocol FEC protocol results in increased expression of KRT18 proteinincreases expression 17545523
D011345 Fenofibrate [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of KRT18 proteinaffects cotreatment|increases expression 18978307
C020326 ferric nitrilotriacetate [[Arachidonic Acid co-treated with ferric nitrilotriacetate co-treated with Ethanol] results in increased expression of CYP2E1 protein] which results in increased expression of KRT18 proteinaffects cotreatment|increases expression 17034788
C070081 fulvestrant KRT18 protein promotes the reaction [fulvestrant inhibits the reaction [Estradiol results in increased activity of ESR1 protein]]decreases reaction|increases activity|increases reaction 20061804
C070081 fulvestrant KRT18 protein promotes the reaction [fulvestrant results in increased degradation of ESR1 protein]increases degradation|increases reaction 20061804
C056933 fumonisin B1 fumonisin B1 results in increased expression of KRT18 mRNAincreases expression 16221962
D005978 Glutathione Glutathione deficiency results in increased expression of KRT18 mRNAincreases expression 15345336
D017313 Fenretinide Fenretinide results in increased expression of KRT18 proteinincreases expression 17387344
C029424 hydrazine hydrazine results in increased expression of KRT18 proteinincreases expression 15370871
D015741 Metribolone Metribolone results in increased expression of KRT18 proteinincreases expression 17152098
17541959
C020300 monomethylarsonic acid monomethylarsonic acid results in decreased expression of KRT18 mRNAdecreases expression 17481689
D009151 Mustard Gas Dimercaprol inhibits the reaction [Mustard Gas results in increased expression of KRT18 mRNA]decreases reaction|increases expression 16377760
D009151 Mustard Gas Mustard Gas results in increased expression of KRT18 mRNAincreases expression 16377760
D015058 1-Naphthylisothiocyanate 1-Naphthylisothiocyanate results in increased expression of KRT18 mRNAincreases expression 15913567
D015058 1-Naphthylisothiocyanate O(2)-vinyl-1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of KRT18 mRNA]decreases reaction|increases expression 15913567
D015058 1-Naphthylisothiocyanate 1-Naphthylisothiocyanate results in increased expression of KRT18 mRNAincreases expression 17522070
D019829 Nevirapine Nevirapine results in increased expression of KRT18 proteinincreases expression 19152342
C107010 O(2)-vinyl-1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate O(2)-vinyl-1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of KRT18 mRNA]decreases reaction|increases expression 15913567
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in increased expression of KRT18 mRNA]affects reaction|increases expression 19482888
D010634 Phenobarbital Phenobarbital results in increased expression of KRT18 mRNAincreases expression 19482888
D010634 Phenobarbital [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of KRT18 mRNAaffects cotreatment|increases expression 19409407
D010634 Phenobarbital [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of KRT18 proteinaffects cotreatment|increases expression 19409407
D010634 Phenobarbital [Phenobarbital co-treated with Diethylnitrosamine] results in increased expression of KRT18 proteinaffects cotreatment|increases expression 20935162
D010882 Piperonyl Butoxide [Diethylnitrosamine co-treated with Piperonyl Butoxide] results in increased expression of KRT18 proteinaffects cotreatment|increases expression 20101389
C006253 pirinixic acid pirinixic acid results in decreased expression of KRT18 mRNAdecreases expression 18445702
17426115
C006253 pirinixic acid pirinixic acid results in increased expression of KRT18 mRNAincreases expression 16221962
C035988 procymidone procymidone results in increased expression of KRT18 mRNAincreases expression 15686871
D011374 Progesterone NCOA2 protein affects the reaction [Progesterone results in decreased expression of KRT18 mRNA]affects reaction|decreases expression 17556502
D011374 Progesterone Progesterone results in decreased expression of KRT18 mRNAdecreases expression 17556502
D012643 Selenium Selenium results in increased expression of KRT18 mRNAincreases expression 19244175
C110991 S-ethyl-N-acetyl-cysteine S-ethyl-N-acetyl-cysteine inhibits the reaction [sodium arsenite results in increased expression of KRT18 mRNA]decreases reaction|increases expression 17340120
C017947 sodium arsenite sodium arsenite affects the expression of KRT18 mRNAaffects expression 20056578
C017947 sodium arsenite sodium arsenite affects the expression of KRT18 proteinaffects expression 20056578
C017947 sodium arsenite sodium arsenite results in increased expression of KRT18 mRNAincreases expression 19524636
C017947 sodium arsenite sodium arsenite results in increased expression of KRT18 proteinincreases expression 19524636
C017947 sodium arsenite S-ethyl-N-acetyl-cysteine inhibits the reaction [sodium arsenite results in increased expression of KRT18 mRNA]decreases reaction|increases expression 17340120
C017947 sodium arsenite sodium arsenite affects the expression of KRT18 mRNAaffects expression 16507464
C017947 sodium arsenite [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of KRT18 mRNAaffects cotreatment|increases expression 16368122
C017947 sodium arsenite sodium arsenite results in decreased expression of KRT18 mRNAdecreases expression 15276417
C017947 sodium arsenite sodium arsenite results in increased expression of KRT18 mRNAincreases expression 17340120
C017947 sodium arsenite sodium arsenite results in increased expression of KRT18 proteinincreases expression 17340120
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of KRT18 mRNAdecreases expression 17884332
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased expression of KRT18 mRNA]decreases reaction|increases expression 11179685
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of KRT18 mRNAincreases expression 17275934
D013752 Tetracycline Tetracycline results in increased expression of KRT18 mRNAincreases expression 17522070
D013755 Tetradecanoylphorbol Acetate [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of KRT18 mRNAaffects cotreatment|increases expression 16368122
D013853 Thioacetamide KRT18 protein affects the reaction [Thioacetamide results in increased expression of MMP13 mRNA]affects reaction|increases expression 18395095
D013853 Thioacetamide KRT18 protein affects the reaction [Thioacetamide results in increased expression of MMP2 mRNA]affects reaction|increases expression 18395095
D013853 Thioacetamide KRT18 protein affects the reaction [Thioacetamide results in increased expression of TIMP1 mRNA]affects reaction|increases expression 18395095
D013853 Thioacetamide Thioacetamide results in increased expression of and results in increased phosphorylation of KRT18 proteinincreases expression|increases phosphorylation 18395095
D013853 Thioacetamide Thioacetamide results in increased expression of KRT18 mRNAincreases expression 18395095
D014212 Tretinoin Tretinoin results in increased expression of KRT18 mRNAincreases expression 17034753
D014212 Tretinoin Tretinoin results in increased expression of KRT18 proteinincreases expression 17387344
D014212 Tretinoin Tretinoin results in increased expression of KRT18 mRNAincreases expression 16236135
C052920 trimethylarsine oxide trimethylarsine oxide results in decreased expression of KRT18 mRNAdecreases expression 17481689
D014635 Valproic Acid Valproic Acid results in increased expression of KRT18 mRNAincreases expression 15345369
C025643 vinclozolin vinclozolin affects the expression of KRT18 mRNAaffects expression 19015723
C025643 vinclozolin vinclozolin results in increased expression of KRT18 mRNAincreases expression 15686871
D014801 Vitamin A Vitamin A results in increased expression of KRT18 mRNAincreases expression 17034753
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced 4-amino-2,6-dinitrotoluene 20.107525203
MESH:D000014 Abnormalities, Drug-Induced Ethanol 20.1018926900 17676605
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 20.106195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 20.1015322242 14514962 11752688
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 20.108875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 8.5019490988
MESH:D000015 Abnormalities, Multiple Vitamin A 8.5010992263
MESH:D000138 Acidosis Ammonium Chloride 8.4018287403
MESH:D000138 Acidosis Ethanol 8.4011192467
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.3117505938
MESH:D055371 Acute Lung Injury pirinixic acid 2.5418653653
MESH:D000230 Adenocarcinoma arsenic trioxide 17.6711798837 19825857
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 17.6720127859 20464547
MESH:D000230 Adenocarcinoma Dimethylnitrosamine 17.6716033868
MESH:D000230 Adenocarcinoma Doxorubicin 17.6717418594
MESH:D000230 Adenocarcinoma Estradiol 17.6711473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 17.6714692618
MESH:D000230 Adenocarcinoma Fenretinide 17.6710697514
MESH:D000236 Adenoma Benzo(a)pyrene 8.946695378
MESH:D000236 Adenoma Diethylnitrosamine 8.946695378 10737359
MESH:D000236 Adenoma Dimethylnitrosamine 8.9419555203
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 19.7517162532 16434500 18056438 17620307 19052882 19061943
MESH:D018248 Adenoma, Liver Cell Phenobarbital 19.7517620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 19.7516434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 19.7516835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.0615276417
MESH:D018246 Adrenocortical Adenoma Arsenic 11.6717306315
MESH:D018246 Adrenocortical Adenoma sodium arsenite 11.6716712894 17306315
MESH:D000419 Albuminuria Doxorubicin 3.9521441931
MESH:D020268 Alcohol-Induced Disorders, Nervous System Ethanol 4.6815451040 15451039
MESH:D000505 Alopecia Tretinoin 3.1115955085
MESH:D000550 Amblyopia Valproic Acid 4.5917688650
MESH:D000686 Amyloidosis Diethylstilbestrol 3.8815469931
MESH:D000740 Anemia Tetrachlorodibenzodioxin 7.1611748828
MESH:D000740 Anemia Vitamin A 7.1616960172
MESH:D018798 Anemia, Iron-Deficiency Vitamin A 4.2516960172
MESH:D000799 Angioedema Acetaminophen 3.2110982225
MESH:D000853 Anophthalmos Ethanol 4.2115513904
MESH:D001008 Anxiety Disorders Ethanol 11.9311141031
MESH:D001008 Anxiety Disorders Valproic Acid 11.9317497229
MESH:D001008 Anxiety Disorders vinclozolin 11.9319015723
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.4619183758
MESH:D020261 Arsenic Poisoning Arsenic 2.6616251483 12569548 18414634 16835338
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 2.8611256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 5.8215885639
MESH:D001169 Arthritis, Experimental Tretinoin 5.8216412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.0916292516
MESH:D001249 Asthma Mustard Gas 6.6410378619
MESH:D001249 Asthma Tretinoin 6.6416456186
MESH:D001249 Asthma Vitamin A 6.6416732791
MESH:D050197 Atherosclerosis Arsenic 2.8612928151 19371607
MESH:D001284 Atrophy fulvestrant 4.2511514358
MESH:D001321 Autistic Disorder Acetaminophen 2.4518445737
MESH:D001321 Autistic Disorder Arachidonic Acid 2.4518582451
MESH:D001321 Autistic Disorder Glutathione 2.4516917939 19056591 19267885 18929414
MESH:D001321 Autistic Disorder Valproic Acid 2.4516609825 18985861 18396377 18316065 18177632 15238991 18775368 17507914 19232924 18558336 18940202 20603192 17157402 17688650 19460635
MESH:D001471 Barrett Esophagus Tretinoin 3.8116935849
MESH:D001714 Bipolar Disorder Valproic Acid 2.7217594078 20046352
MESH:D001768 Blister Mustard Gas 4.5319167455
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 28.6116206674
MESH:D001778 Blood Coagulation Disorders Clofibrate 28.6119483382
MESH:D001778 Blood Coagulation Disorders pirinixic acid 28.6119483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 28.6112125929
MESH:D001778 Blood Coagulation Disorders Thioacetamide 28.6119483382
MESH:D001778 Blood Coagulation Disorders Tretinoin 28.6116206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.1515340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 6.6015746008
MESH:D001848 Bone Diseases, Developmental Valproic Acid 6.608888407
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 4.0614601052
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 4.7017868700
MESH:D001930 Brain Injuries Progesterone 3.6515665606 15845082 15380490
MESH:D002545 Brain Ischemia beta Carotene 4.4716157235
MESH:D001932 Brain Neoplasms Doxorubicin 7.3017150277
MESH:D001932 Brain Neoplasms Fenretinide 7.3016187019
MESH:D001943 Breast Neoplasms marker/mechanism 20061804
MESH:D001943 Breast Neoplasms 4-(1H-imidazol-1-yl)retinoic acid 11.1417387344 17145897
MESH:D001943 Breast Neoplasms alitretinoin 11.1416344269
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 11.1420146248 17474063
MESH:D001943 Breast Neoplasms Cacodylic Acid 11.1417474063
MESH:D001943 Breast Neoplasms Diethylnitrosamine 11.1417474063
MESH:D001943 Breast Neoplasms Diethylstilbestrol 11.1417129689 15324884
MESH:D001943 Breast Neoplasms Doxorubicin 11.1418628466 16595493 16096432 16826403 15136595 16115903 19526202 16322301 18695136 17369602 16264153 15939500 15668708 11325840 18234424 15567936 18382427 15692762 17426702 15634643 17983394 15993339 15994142 16935488
MESH:D001943 Breast Neoplasms Estradiol 11.1417261762 18497071 17289903 19861407 12948864 17018787 14630087 16675129
MESH:D001943 Breast Neoplasms FEC protocol 11.1417145825 16682728 15970926
MESH:D001943 Breast Neoplasms Fenretinide 11.1416601279
MESH:D001943 Breast Neoplasms fulvestrant 11.1418984771
MESH:D001943 Breast Neoplasms Progesterone 11.1415562024 17614352 16175315
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 11.1420435547
MESH:D001943 Breast Neoplasms Tretinoin 11.1416873071 16443354 16166294
MESH:D001989 Bronchiolitis Obliterans Mustard Gas 4.5315286001
MESH:D029481 Bronchitis, Chronic Mustard Gas 4.3417687719 10378619
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 10.9416813970
MESH:D001997 Bronchopulmonary Dysplasia Vitamin A 10.9417426644 17377406
MESH:D002051 Burkitt Lymphoma arsenic trioxide 3.7511589617
MESH:D002056 Burns Ethanol 4.0416374292
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 3.8416111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.173786805 15721981 16097048 16227642 16192424 15673190 18705752 15700767 16050911 16011737 10355542 16124888
MESH:D002276 Carcinoid Tumor Doxorubicin 4.1716051944
MESH:D002277 Carcinoma Dimethylnitrosamine 6.6819555203
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 6.6816835633
MESH:D002280 Carcinoma, Basal Cell Arsenic 3.2115504454 17687452
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.5216168501
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 38.3716705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 38.3716705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 38.373084413
MESH:D006528 Carcinoma, Hepatocellular Arsenic 38.3717306315 16507464
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 38.3715073043 14691202 11135700 16217749 15553829
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 38.3718788625
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 38.3721159647 19171122 18785209 16878318 16681979 19052882 18691550 18506893 17428255 17761372 19418558 16698587 20432363 16328049 20084675 19208518 18494052 17173139 20524982 20214788 16807293 16830150 19107877 18393292 20007298 16288022 19394651 19539802 17162532 18788625 18665156 3084413 10737359 16935385 20101231 19701751 18971187 16502159 19822196 17978847 20935162 18210153 19519916 17055752 3581430 16569478 18056438 10672840 19383236 19919837 11831363 16540662 16779866 20727157 19335982 20514400 20512989 17138121 18978308
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 38.3716924424 15948411
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 38.3717876044 18059187 16023760 16234567
MESH:D006528 Carcinoma, Hepatocellular Estradiol 38.3716924424
MESH:D006528 Carcinoma, Hepatocellular Ethanol 38.3718788625 15763234 15289165
MESH:D006528 Carcinoma, Hepatocellular Fenretinide 38.3716270382 17159502
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 38.376705139 17173139 20935162 20007298 1701930
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 38.3715276417 17306315 16507464
MESH:D006528 Carcinoma, Hepatocellular Thioacetamide 38.3717997003
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 38.371917145
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.2419014326
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 6.0616201981 1485588
MESH:D002292 Carcinoma, Renal Cell ferric nitrilotriacetate 6.068340253
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.5712490120
MESH:D002294 Carcinoma, Squamous Cell Arsenic 25.6418922899 15504454 17687452
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 25.6420419170
MESH:D002294 Carcinoma, Squamous Cell Dimethylnitrosamine 25.6416033868
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 25.646189445
MESH:D002294 Carcinoma, Squamous Cell Fenretinide 25.6416274795
MESH:D002294 Carcinoma, Squamous Cell Glutathione 25.6417015178
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 25.6418572023
MESH:D002294 Carcinoma, Squamous Cell Tetradecanoylphorbol Acetate 25.6418922899
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 25.6416051514 16096774
MESH:D002295 Carcinoma, Transitional Cell Arsenic 3.5318640142
MESH:D006332 Cardiomegaly Ethanol 5.5819332462
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 5.5818670907 18850075 16120746
MESH:D009202 Cardiomyopathies Doxorubicin 3.1016612575 18627295 15811867 17308081 16455267 16109756 17924179 16731534 16242529 17351982 17382496 15476868 15792986 17519947 17928571 16269455 16278810 16364871 16952015 15505089 17007740 17329180 17974986 17131338 16651473
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.6917334414 16243910
MESH:D002318 Cardiovascular Diseases Arsenic 3.0019152805 17938729 15738583
MESH:D002340 Carotid Artery Diseases Arsenic 3.7718022660 16973168
MESH:D002386 Cataract 4-amino-2,6-dinitrotoluene 10.0614694615
MESH:D002386 Cataract Acetaminophen 10.0610977129
MESH:D002386 Cataract Tretinoin 10.0617460283
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 16.336135515
MESH:D002471 Cell Transformation, Neoplastic Clofibrate 16.331399818
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 16.332727394 17174075 21159647 7505956
MESH:D002471 Cell Transformation, Neoplastic Estradiol 16.3318566989
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 16.3319524636 20056578
MESH:D002493 Central Nervous System Diseases Phenobarbital 3.644080065
MESH:D018290 Cervical Intraepithelial Neoplasia Fenretinide 10.9016154183
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 10.9016129372
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.4520734317
MESH:D015362 Child Nutrition Disorders Vitamin A 4.8416153327
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 13.0419052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 13.0416835633
MESH:D018281 Cholangiocarcinoma Thioacetamide 13.0418291259
MESH:D002761 Cholangitis 1-Naphthylisothiocyanate 5.5612912871
MESH:D002779 Cholestasis 1-Naphthylisothiocyanate 15.4212927374 15500046 18590720 15913567 16629650 18164287 7624871 19486331
MESH:D002779 Cholestasis Ethinyl Estradiol 15.4215861022 17681005 17110522 16105132 11677210 16919318 17333356
MESH:D002779 Cholestasis pirinixic acid 15.4219176532
MESH:D002779 Cholestasis Vitamin A 15.4216175620
MESH:D002780 Cholestasis, Intrahepatic 1-Naphthylisothiocyanate 5.2210220858 19407337
MESH:D002822 Choriocarcinoma Tretinoin 4.5216461808
OMIM:215600 CIRRHOSIS, FAMILIAL marker/mechanism
MESH:D002971 Cleft Lip Ethanol 3.2215513904
MESH:D002972 Cleft Palate Ethanol 11.6015513904
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 11.6016354765 8697196 12621046 15340226 15668235
MESH:D002972 Cleft Palate Tretinoin 11.609407595
MESH:D002972 Cleft Palate Vitamin A 11.6016054864
MESH:D003092 Colitis Selenium 7.4817936198
MESH:D003092 Colitis Tretinoin 7.4817035595
MESH:D003110 Colonic Neoplasms Vitamin A 2.9217219422 16267017
MESH:D015179 Colorectal Neoplasms arsenic trioxide 3.1320501625
MESH:D015179 Colorectal Neoplasms Doxorubicin 3.1318802399 18259882
MESH:D015179 Colorectal Neoplasms Fenretinide 3.1317273769
MESH:D000013 Congenital Abnormalities 4-amino-2,6-dinitrotoluene 7.4215095906
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 7.4214669216 17141729
MESH:D023903 Coronary Restenosis arsenic trioxide 3.5912609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 8.1510525206
MESH:D019465 Craniofacial Abnormalities Ethanol 8.1510194807 15451039 15451040 19302082 11873399 11198716 15513904
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 8.1520055451 10048152 15322242
MESH:D019465 Craniofacial Abnormalities Tretinoin 8.159142499 16925845 8800419 10589399 9125849 17551590 9211117 14991402 9224671 9664655
MESH:D019465 Craniofacial Abnormalities Valproic Acid 8.1517688650 8888407 16575769
MESH:D019465 Craniofacial Abnormalities Vitamin A 8.1510992263
MESH:D003456 Cryptorchidism Diethylstilbestrol 9.3912952375 16002989
MESH:D003456 Cryptorchidism vinclozolin 9.3914966744
MESH:D003490 Cyanosis 2,4-dinitrotoluene 8.8718551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 8.8718551238
MESH:D003550 Cystic Fibrosis Glutathione 3.9519747007
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.5215213294
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.1018249437
MESH:D003922 Diabetes Mellitus, Type 1 Vitamin A 3.2816506275
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 3.5620387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 3.5617107852
MESH:D003928 Diabetic Nephropathies Estradiol 2.8819279558
MESH:D003929 Diabetic Neuropathies Progesterone 3.8817187935
MESH:D056486 Drug-Induced Liver Injury 1-Naphthylisothiocyanate 66.5017522070 7624871 20133375 18289764
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 66.5021346803 18551238
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 66.5018551238 21346803
MESH:D056486 Drug-Induced Liver Injury 4-amino-2,6-dinitrotoluene 66.5021346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 66.5010915739 12705907 18071297 12958197 11287661 19370779 10774834 17522070 19420014 15968718 15619225 19739265 12594235 11421492 16485898 19416960 11529661 19085960 19164858 16081117 10663392 14725611 11743745 11461765 12540782 16177239 12392966 16781746 12153990 11834606 18713872 16227642 16393943 17562736 19923254 16109766 2444490 14986274 11739529 17906064 14550746
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 66.5021278145 6884620 2869522 3786805 15968718 11566570 19085960 3732212 4309450 7179309 16177239 15027814 9327722 19336974 17522070 15998439 10915739 10092053 7440962 7120509 16227642 6623471
MESH:D056486 Drug-Induced Liver Injury Chloroform 66.507120509 17522070 6884620 7440962 3104120 3732212 6623471 2862719
MESH:D056486 Drug-Induced Liver Injury cyanoginosin LR 66.5017654400
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 66.5019107877
MESH:D056486 Drug-Induced Liver Injury Dimethylnitrosamine 66.508172417
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 66.5017416283
MESH:D056486 Drug-Induced Liver Injury Erythromycin Estolate 66.5017522070 14998559
MESH:D056486 Drug-Induced Liver Injury Ethanol 66.5011566570
MESH:D056486 Drug-Induced Liver Injury fumonisin B1 66.5016221962
MESH:D056486 Drug-Induced Liver Injury Nevirapine 66.5014986274
MESH:D056486 Drug-Induced Liver Injury O(2)-vinyl-1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate 66.5012540782
MESH:D056486 Drug-Induced Liver Injury Selenium 66.5015131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 66.5020420201
MESH:D056486 Drug-Induced Liver Injury Tetracycline 66.5017522070
MESH:D056486 Drug-Induced Liver Injury Thioacetamide 66.5012963478
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 66.5019641884 1733752
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.4619426721
MESH:D004362 Drug Toxicity Doxorubicin 6.5218602426
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 6.5211462148
MESH:D015352 Dry Eye Syndromes Vitamin A 5.1816146918
MESH:D050171 Dyslipidemias Clofibrate 7.6216707586
MESH:D050171 Dyslipidemias Fenofibrate 7.6216707586
MESH:D004421 Dystonia Phenobarbital 8.511851702
MESH:D004421 Dystonia Valproic Acid 8.511851702
MESH:C538011 Eales disease Vitamin A 4.989068938
MESH:D004480 Ectromelia Vitamin A 5.1816054864
MESH:D004487 Edema Arachidonic Acid 15.809831321 16716910 9599246 11698051 7990266 15177302
MESH:D004487 Edema Mustard Gas 15.8011402378 9260866 11428647 11428631
MESH:D004487 Edema pirinixic acid 15.8012083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 15.8011000095 12711302
MESH:D004487 Edema Tetradecanoylphorbol Acetate 15.809599246 15177302 7812673 16716910 8113982 11698051 8273558
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 9.8315322242 16714409 18230668
MESH:D004489 Edema, Cardiac Tretinoin 9.8318230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 7.0712538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 7.0717692515
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 4.0716402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 18.7816804899 15700306
MESH:D016889 Endometrial Neoplasms Doxorubicin 18.7817359293
MESH:D016889 Endometrial Neoplasms Estradiol 18.7811473722 19148513 18566989
MESH:D016889 Endometrial Neoplasms Fenofibrate 18.7816569247
MESH:D016889 Endometrial Neoplasms Tretinoin 18.7816569247
MESH:D004715 Endometriosis Progesterone 7.1116134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 7.1110568697 9294722
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 4.5218037988
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 8.773659116
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 8.7717275665 3659116
MESH:D004828 Epilepsies, Partial Phenobarbital 7.863922381 11558140
MESH:D004828 Epilepsies, Partial Valproic Acid 7.863922381 16628512
MESH:D004827 Epilepsy Phenobarbital 5.4720417680
MESH:D004827 Epilepsy Valproic Acid 5.4718234410 20417680
MESH:D004832 Epilepsy, Absence Phenobarbital 7.106401628
MESH:D004832 Epilepsy, Absence Valproic Acid 7.106254150 7562514 6426943
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 9.277750514
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 9.277750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 8.413659116
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 8.413659116
MESH:D004890 Erythema Mustard Gas 4.539357497
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.4816302075
MESH:D004938 Esophageal Neoplasms arsenic trioxide 8.7012903497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 8.7016530937
MESH:D004938 Esophageal Neoplasms Dimethylnitrosamine 8.7017016578
MESH:D004938 Esophageal Neoplasms Ethanol 8.7016704527
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 7.2311564622
MESH:D005124 Eye Abnormalities Tretinoin 7.239664655 16938888
MESH:D005218 Fat Necrosis Thioacetamide 5.0816456712
MESH:D005234 Fatty Liver arsenic trioxide 38.7815073043
MESH:D005234 Fatty Liver Carbon Tetrachloride 38.7815959796 61145 12631006 19224547 12795759 16239168 17595544 16045604
MESH:D005234 Fatty Liver Clofibrate 38.7819224547
MESH:D005234 Fatty Liver Diethylnitrosamine 38.7820387270 21071580
MESH:D005234 Fatty Liver Ethanol 38.7818620774 19236843 16409862
MESH:D005234 Fatty Liver Ethinyl Estradiol 38.7815345470
MESH:D005234 Fatty Liver pirinixic acid 38.7819236843 20131406
MESH:D005234 Fatty Liver Tetracycline 38.7819224547 16917069
MESH:D005234 Fatty Liver Valproic Acid 38.7814986274 19224547
MESH:D005235 Fatty Liver, Alcoholic Ethanol 5.0317920746
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 3.2515751030 16611131 16002989 16513791 16534752
MESH:D005310 Fetal Alcohol Syndrome Ethanol 4.6716946407 15451040 10194807 15513904
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 2.8511858732
MESH:D005315 Fetal Diseases Valproic Acid 4.2516575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 3.548888407 18558336
MESH:D005327 Fetal Resorption Vitamin A 4.7316054864
MESH:D005334 Fever Arachidonic Acid 4.1111852909
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 3.9619069698
MESH:D005355 Fibrosis Carbon Tetrachloride 11.2518705752
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 11.2520067830
MESH:D005355 Fibrosis Tretinoin 11.2517994277
MESH:D005534 Foot Diseases Arsenic 4.926392382
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.6716904648
MESH:D005756 Gastritis Acetaminophen 9.0116983495
MESH:D005756 Gastritis Ethanol 9.0115046732
MESH:D030342 Genetic Diseases, Inborn vinclozolin 4.3116973722
MESH:D005832 Genital Diseases, Male vinclozolin 4.6616417039
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 10.7416452187
MESH:D005833 Genital Neoplasms, Female sodium arsenite 10.7416452187
MESH:D005909 Glioblastoma Doxorubicin 9.5117150277
MESH:D005909 Glioblastoma Fenretinide 9.5116187019
MESH:D005909 Glioblastoma Tretinoin 9.5117312396
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 3.9610696789
MESH:D006258 Head and Neck Neoplasms Doxorubicin 6.3715692506
MESH:D006258 Head and Neck Neoplasms Tretinoin 6.3716096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.5216084493
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 12.9920471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 12.9911294989 10048152
MESH:D006330 Heart Defects, Congenital Tretinoin 12.9914991402 9664655
MESH:D006330 Heart Defects, Congenital Vitamin A 12.9910992263 16080930
MESH:D006331 Heart Diseases Doxorubicin 3.0414766674 16707910 16244371 18674790 17888722 12587719 16495754 16144979 18006777 16330681 17875725 16244372 16879835
MESH:D006333 Heart Failure Doxorubicin 9.4017481944
MESH:D006333 Heart Failure pirinixic acid 9.4020558911
MESH:D006333 Heart Failure Selenium 9.4017162251
MESH:D006394 Hemangiosarcoma Doxorubicin 3.3415692506
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.7711000095
MESH:D006501 Hepatic Encephalopathy Thioacetamide 4.0118665440 15929193 17276928
MESH:D006505 Hepatitis 1-Naphthylisothiocyanate 12.4618590720
MESH:D006505 Hepatitis Carbon Tetrachloride 12.4619110552 19900420
MESH:D006505 Hepatitis Thioacetamide 12.4616456712
MESH:D006529 Hepatomegaly fumonisin B1 15.7316221962
MESH:D006529 Hepatomegaly Phenobarbital 15.7316109766
MESH:D006529 Hepatomegaly pirinixic acid 15.7316221962 19772884 18467677 19176532
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 15.7315340226 12621046 16120746
MESH:D006548 Hernia, Diaphragmatic Vitamin A 3.3616490937 15707848 16292552 16863852 17436238 16877224
MESH:D006558 Herpes Genitalis Estradiol 4.3915709030
MESH:D015658 HIV Infections beta Carotene 9.1716960176
MESH:D015658 HIV Infections Nevirapine 9.1711141242
MESH:D015658 HIV Infections Vitamin A 9.1716960176
MESH:D006679 HIV Seropositivity Vitamin A 4.9717209195
MESH:D006689 Hodgkin Disease Doxorubicin 5.7418501091 17606976 15147373
MESH:D006689 Hodgkin Disease sodium arsenite 5.7412676792
MESH:D019584 Hot Flashes Estradiol 3.1217088409
MESH:D006849 Hydrocephalus Valproic Acid 4.2417688650
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.418697196 16354765 15340226 16959395 18606429
MESH:D006930 Hyperalgesia Acetaminophen 10.1616870215
MESH:D006930 Hyperalgesia Ethanol 10.1618783367
MESH:D006930 Hyperalgesia Tretinoin 10.1616870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 3.9116899240
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 3.9616778211
MESH:D006943 Hyperglycemia pirinixic acid 2.6420558911
MESH:D017488 Hyperkeratosis, Epidermolytic Arsenic 3.9117050553
MESH:D006965 Hyperplasia Diethylstilbestrol 3.8312960047 14722030
MESH:D006973 Hypertension Arsenic 4.2916076760 9931084 11953799
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 4.2918850075 18670907
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.4815338365
MESH:D006986 Hypervitaminosis A Vitamin A 5.5316054864
MESH:D006987 Hypesthesia Arsenic 4.9216093927
MESH:D007021 Hypospadias Diethylstilbestrol 9.2116002989
MESH:D007021 Hypospadias Ethinyl Estradiol 9.2116945680 16569931
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 3.7915869954
MESH:D007246 Infertility Diethylstilbestrol 3.7615036965
MESH:D007247 Infertility, Female Ethinyl Estradiol 2.8812013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 12.4617937319
MESH:D007248 Infertility, Male fulvestrant 12.4611514358
MESH:D007248 Infertility, Male sodium arsenite 12.4615346721 12646999
MESH:D007248 Infertility, Male vinclozolin 12.4616467254
MESH:D007249 Inflammation Arachidonic Acid 15.2617371808 15177302 9831321
MESH:D007249 Inflammation Diethylnitrosamine 15.2618785209
MESH:D007249 Inflammation Mustard Gas 15.269260866 9357497 8975870 11402378 17524151 11428631 11428620 11428647 16001271
MESH:D007249 Inflammation Progesterone 15.2615869954
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 15.2612200463 12878042
MESH:D007249 Inflammation Tetradecanoylphorbol Acetate 15.2611698051 7812673 7562506 8273558 15177302
MESH:D007251 Influenza, Human Selenium 3.5616624496
MESH:D007333 Insulin Resistance Estradiol 5.7516393666 16627594
MESH:D007333 Insulin Resistance pirinixic acid 5.7516306350
MESH:D007410 Intestinal Diseases Tretinoin 3.1617994277
MESH:D019586 Intracranial Hypertension Vitamin A 5.1815955940
MESH:D007569 Jaw Abnormalities Ethanol 13.9315513904
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 13.9316580747
MESH:D007569 Jaw Abnormalities Tretinoin 13.9315992940 17551590
MESH:D007642 Keratosis Arsenic 4.3616930632 12749816
MESH:D017492 Keratosis, Seborrheic alitretinoin 5.0116144296
MESH:D007674 Kidney Diseases Acetaminophen 14.9212587719 15629191
MESH:D007674 Kidney Diseases Doxorubicin 14.9215699352 15369732 16775033
MESH:D007674 Kidney Diseases Estradiol 14.9215618244
MESH:D007674 Kidney Diseases ferric nitrilotriacetate 14.9218617210 15834431
MESH:D007674 Kidney Diseases sodium arsenite 14.9220008137
MESH:D007676 Kidney Failure, Chronic Doxorubicin 8.1116707910
MESH:D007676 Kidney Failure, Chronic Selenium 8.1116518626
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 17.9316705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 17.9316705839
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 17.9316762066 15003126 14681315
MESH:D007680 Kidney Neoplasms Estradiol 17.9315610895
MESH:D007680 Kidney Neoplasms ferric nitrilotriacetate 17.9318055543 9667754
MESH:D007859 Learning Disorders Diethylstilbestrol 7.7717184923
MESH:D007859 Learning Disorders Ethanol 7.7715451040
MESH:D007938 Leukemia arsenic trioxide 5.1715070760
MESH:D007938 Leukemia Tretinoin 5.1717143497
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 4.5216085563
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.2317077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 3.6816972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 2.9514633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 7.6119077051
MESH:D007951 Leukemia, Myeloid Tretinoin 7.6116482212 19285840 16932348
MESH:D015470 Leukemia, Myeloid, Acute ABT-737 7.5317097560
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 7.5316968895 16467208 19850784 17050201 20471514
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 7.5319850784 16294345 17596541
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 7.5316294345 17596541
MESH:D015473 Leukemia, Promyelocytic, Acute Arsenic 10.2617339181
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 10.2617107899 16966277 9834237 16823087 11468182 15336539 16112521 15622746 19075265 12679006 19035177 19225113 19642359 17649720 12712474 17869043 17712046 16330433 16891316 11161223 15213294 12018890 16331271 17217047 15748426
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 10.2617649720 16331271 17712046 19029980 17339181 17301526 9834237 17368321 19642359 15748426 16891316 12679006 19035177 16935935 17107899 19225113 19075265 16140955 17361223 17506722 16823087 17217047 16788101 16766008 17294898
MESH:D015458 Leukemia, T-Cell arsenic trioxide 3.7616882451
MESH:D007972 Leukoplakia, Oral Fenretinide 5.4116707609
MESH:D007984 Leydig Cell Tumor vinclozolin 4.1116417039
MESH:D017880 Limb Deformities, Congenital Ethanol 11.1317676605
MESH:D017880 Limb Deformities, Congenital Tretinoin 11.139224671
MESH:D017880 Limb Deformities, Congenital Vitamin A 11.1316054864
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 16.7311903743 16943688 21278145 11408273 17157831 16221502 17334410 17174718 16239168
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 16.7320032147 18407596 18522880 19638242 18665156
MESH:D008103 Liver Cirrhosis Ethanol 16.7315289165
MESH:D008103 Liver Cirrhosis Phenobarbital 16.7321047994
MESH:D008103 Liver Cirrhosis Vitamin A 16.7316256175
MESH:D008104 Liver Cirrhosis, Alcoholic Ethanol 4.4718295389
MESH:D008106 Liver Cirrhosis, Experimental marker/mechanism 17072980 15999547 18395095
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 18.1312586293 15876570 18412020 18166357 12666154 17944888 17823541 15893842 15370692 12632512 14716496 16192424 12546737 14724832 17481882 17631135 17714472 15052691 12445418 15650968 17698563 18481824 12632514 12958196 18251166 17565644 16015684 11481614 16248980 17900296 12741479 17640975 18210741 12445421 14512876 16097048 15338365 13678700 17761835 16116963 15362042 18205269 17805973 18187930 15818738 18418968 12389079 15057751 16136751 17525996 17557913 12667390 17922224 12609069 12898905 18395095 18054572 18156304 15931870 18420326 18472332 16011737 14748882 14620537 18376398 17766677 15996030 17976157 16638106 18705752 17869086 15959796 12649538 18317297 18395914 18006644 15730626 16033810 17708605 18263696 18277467 14716833 18472094 17721639 15673190 20821823 16027843 15925388 18339082 18279442 10355542 18429990 15123356
MESH:D008106 Liver Cirrhosis, Experimental Dimethylnitrosamine 18.1317203207 16169303 15369754 14643895 16603200 17198567 15744066 15138612 18239293 15571005 18629640 15099470 15504291 16544323 15591649 15733078 17534399 15081153 15161499 18672772 15723089 17432682 15798949 16042886 16570917 15067225 14568256 18210741 15577212 17465448 15793283 17640959 17201889 15086199 15383259 17196135 17881167 17348192 18637143 18095165 14726149 18364076 16627068 15479170 18567088 17719030 18371158 15864749 15492853 15366600 14659978 15942678 17724770 15842777 15298665 17666798 12925901 18237412 15763062 15339415 17036385 14709902 16009107 12918455 16270385
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 18.1316595196 16439617
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 18.1314659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental Ethanol 18.1318166357
MESH:D008106 Liver Cirrhosis, Experimental Fenofibrate 18.1315474484
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 18.1315474484
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 18.1312878042
MESH:D008106 Liver Cirrhosis, Experimental Thioacetamide 18.1311481614 17292413 18263696 15095483 10677585 15158331 15288473 11172339 12679928 16343077 14739098 17355460 16098781 18295389 16489207 18031379 12531686 18380797 16097051 11682029 15334695 15465738 12891558 15078482 18606216 16126171 18395095 18458672 12085344 15288472 17050028 15474484 18416461 18032466 17127702 15716488 15075984 16248980 16511523 15316131 12175628 17629604 12557150 15362042 18615449
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 18.1318397230 16248980
MESH:D008106 Liver Cirrhosis, Experimental Vitamin A 18.1316248980
MESH:D008107 Liver Diseases 1-Naphthylisothiocyanate 19.3017184895
MESH:D008107 Liver Diseases Acetaminophen 19.3012587719 12969438 16611625 19460945 16610002 19014921 11587558 19784758
MESH:D008107 Liver Diseases Arsenic 19.3011134558
MESH:D008107 Liver Diseases Carbon Tetrachloride 19.3015830285 15720792 17285989 16964402 16246199
MESH:D008107 Liver Diseases Diethylnitrosamine 19.3017034775
MESH:D008107 Liver Diseases Phenobarbital 19.3019363144
MESH:D008107 Liver Diseases Thioacetamide 19.3016337175 18374380 15158337
MESH:D008107 Liver Diseases Vitamin A 19.3016175620
MESH:D008108 Liver Diseases, Alcoholic Ethanol 9.5217207112 17347304
MESH:D008108 Liver Diseases, Alcoholic Vitamin A 9.5216762690
MESH:D017093 Liver Failure Carbon Tetrachloride 3.5515123358
MESH:D017114 Liver Failure, Acute Acetaminophen 18.7816871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 18.7816899240 14706259
MESH:D017114 Liver Failure, Acute Dimethylnitrosamine 18.7817457977
MESH:D017114 Liver Failure, Acute Thioacetamide 18.7815633222 12479984 15313186 17276928
MESH:D008113 Liver Neoplasms marker/mechanism 19409407
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 43.857678174
MESH:D008113 Liver Neoplasms Arsenic 43.8516368122
MESH:D008113 Liver Neoplasms arsenic trioxide 43.8514682389
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 43.8521137059 20195826
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 43.8519294768
MESH:D008113 Liver Neoplasms Diethylnitrosamine 43.8520405173 12112319 20492335 20101389 19833225 19499222 19427195 19294768 20118626 15175105 21047994 19255062 18978307 19690152 10737359 18644402 19256749 21278145 16942905 19426721 19551842 19996281 9163691 18977376 21071580 20583210 19090486 20137499 2422723 18754104 19642983 12771043 20501860 19812893 19073162 18648771 2862719 19638242 15885732 19254457 20434301 20452335 19850985 21167192
MESH:D008113 Liver Neoplasms Diethylstilbestrol 43.8515890375 16712894
MESH:D008113 Liver Neoplasms Dimethylnitrosamine 43.8515890375 3113478
MESH:D008113 Liver Neoplasms Fenofibrate 43.8518978307
MESH:D008113 Liver Neoplasms Phenobarbital 43.8519482888 19812893 8742319 15975961 19073162 21047994
MESH:D008113 Liver Neoplasms Piperonyl Butoxide 43.8519690152 18648771 20101389 15890375
MESH:D008113 Liver Neoplasms pirinixic acid 43.8516377806 20007298 15890375
MESH:D008113 Liver Neoplasms sodium arsenite 43.8516712894 15276417
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 43.8516984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 38.982876784 2876786 6135515
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 38.9820377131
MESH:D008114 Liver Neoplasms, Experimental beta Carotene 38.9817113696
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 38.9815583823 12014681
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 38.9819539802 19004024 18544905 18164116 18282651 18253720 16267830 19519916 18079962 19126423 19009564 17174075 18775883 18093689 18308698 21159647 17854601 3124819 16842330 17942915 2563599 9362446
MESH:D008114 Liver Neoplasms, Experimental Dimethylnitrosamine 38.981848544 15603536 6150874
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 38.9817085340 16842330
MESH:D008114 Liver Neoplasms, Experimental Fenofibrate 38.9818253720 18775883
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 38.9817172636 18308698 1399818 2563599 6150874
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 38.9812151625
MESH:D008114 Liver Neoplasms, Experimental Vitamin A 38.9817113696
MESH:D008133 Long QT Syndrome arsenic trioxide 2.8615213294
MESH:D008171 Lung Diseases Mustard Gas 9.9318702808 18161513
MESH:D008171 Lung Diseases sodium arsenite 9.9319095001
MESH:D008171 Lung Diseases Vitamin A 9.9316863852
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 3.6317228818
MESH:D008175 Lung Neoplasms alitretinoin 20.2716413115
MESH:D008175 Lung Neoplasms Arsenic 20.2717976673 17306315 19168569
MESH:D008175 Lung Neoplasms arsenic trioxide 20.2711798837 19825857
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 20.2718816296 17053015 20464547 6695378 18569708 20135361 20869020 18520028 20064080
MESH:D008175 Lung Neoplasms beta Carotene 20.2716401635
MESH:D008175 Lung Neoplasms Diethylnitrosamine 20.2721163286 20970405 6695378 20512841
MESH:D008175 Lung Neoplasms Dimethylnitrosamine 20.2716061637 11884234 19555203
MESH:D008175 Lung Neoplasms Doxorubicin 20.2717418594 6189445
MESH:D008175 Lung Neoplasms Mustard Gas 20.278781369 3148597
MESH:D008175 Lung Neoplasms sodium arsenite 20.2719931552 16712894 15276417 17306315 17077188
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 20.2711884234 19555203
MESH:D008175 Lung Neoplasms Tetradecanoylphorbol Acetate 20.2711807781
MESH:D008181 Lupus Nephritis Diethylstilbestrol 4.5215166399
MESH:D008223 Lymphoma Diethylstilbestrol 6.2015700306
MESH:D008223 Lymphoma Doxorubicin 6.2016098063
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 3.2817654614
MESH:D016399 Lymphoma, T-Cell Doxorubicin 3.9615621674
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 4.8816002989
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 18.0515458769
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 18.0511807958 17203775 16891317 11408345
MESH:D008325 Mammary Neoplasms, Experimental Fenretinide 18.0510697514
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 18.0511408345 17203775
MESH:D008325 Mammary Neoplasms, Experimental Selenium 18.0515318939
MESH:D008325 Mammary Neoplasms, Experimental Tetradecanoylphorbol Acetate 18.058985016
MESH:D020149 Manganese Poisoning Estradiol 3.8519453300
MESH:D008527 Medulloblastoma Tretinoin 2.5017453147
MESH:D008545 Melanoma Doxorubicin 6.0816827129
MESH:D008545 Melanoma Fenretinide 6.0816270382
MESH:D008545 Melanoma sodium arsenite 6.0816487513 19082730
MESH:D008545 Melanoma Tretinoin 6.0816752155
MESH:D008546 Melanoma, Experimental Acetaminophen 2.9619513568
MESH:D008569 Memory Disorders Ethanol 3.6018411066 15451040
MESH:D008591 Meningomyelocele Tretinoin 3.8116940565
MESH:D008654 Mesothelioma Doxorubicin 5.3117638057
MESH:D008654 Mesothelioma Selenium 5.3115107826
MESH:D008881 Migraine Disorders Valproic Acid 2.7318803445 18765137
MESH:D028361 Mitochondrial Diseases Doxorubicin 3.9315792986
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 7.1516381670
MESH:D009062 Mouth Neoplasms Fenretinide 7.1516274795
MESH:D052016 Mucositis Doxorubicin 4.1717415656
MESH:D009101 Multiple Myeloma arsenic trioxide 6.1015949261 19417148 14977855 19549372 11468182
MESH:D009101 Multiple Myeloma Vitamin A 6.1016374440
MESH:D009135 Muscular Diseases pirinixic acid 2.9016239165
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 3.468888407
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.0318349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 10.0416105982 16882451
MESH:D009190 Myelodysplastic Syndromes Tretinoin 10.0417596541
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 10.0417596541
MESH:D009203 Myocardial Infarction Doxorubicin 4.7015857846 19429709
MESH:D009203 Myocardial Infarction pirinixic acid 4.7019151258
MESH:D017202 Myocardial Ischemia Arsenic 7.3215371236
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 7.3212213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 6.6116810080
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 6.6116411023
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 3.8517484760
MESH:D009336 Necrosis 2,4-dinitrotoluene 8.2718551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 8.277678174 18551238
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.3716624393
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 4.903581430 9029167
MESH:D009362 Neoplasm Metastasis Doxorubicin 4.9018259882
MESH:D009369 Neoplasms alitretinoin 22.2516946489
MESH:D009369 Neoplasms Benzo(a)pyrene 22.2511141357
MESH:D009369 Neoplasms beta Carotene 22.2517051425
MESH:D009369 Neoplasms Diethylstilbestrol 22.2515313581
MESH:D009369 Neoplasms Fenretinide 22.2515958647 17353921
MESH:D009369 Neoplasms pirinixic acid 22.2517405874
MESH:D009369 Neoplasms sodium arsenite 22.2511559025
MESH:D009369 Neoplasms Tretinoin 22.2516946489 16594593
MESH:D009374 Neoplasms, Experimental sodium arsenite 3.0620056578
MESH:D009376 Neoplasms, Hormone-Dependent Nevirapine 5.5019152342
MESH:D009389 Neovascularization, Pathologic Estradiol 3.1117289903
MESH:D009395 Nephritis, Interstitial Tetracycline 4.159884423
MESH:D009401 Nephrosis Doxorubicin 4.1616899518 16636307
MESH:D009404 Nephrotic Syndrome Doxorubicin 3.4716889571 15640375
MESH:D009421 Nervous System Malformations Diethylstilbestrol 18.5811399458
MESH:D009421 Nervous System Malformations Estradiol 18.5816427766 11399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 18.5814600291
MESH:D009421 Nervous System Malformations Tretinoin 18.589125849
MESH:D009436 Neural Tube Defects Arsenic 22.7916620997
MESH:D009436 Neural Tube Defects arsenic trioxide 22.7910525206
MESH:D009436 Neural Tube Defects sodium arsenite 22.7912854658
MESH:D009436 Neural Tube Defects Tretinoin 22.799142499
MESH:D009436 Neural Tube Defects Valproic Acid 22.7916359493 8888407
MESH:D009436 Neural Tube Defects Vitamin A 22.7917400914
MESH:D009447 Neuroblastoma Doxorubicin 2.9115555623
MESH:D019636 Neurodegenerative Diseases Acetaminophen 6.4618514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 6.4620387270
MESH:D020078 Neurogenic Inflammation Arsenic 3.8017056641
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.4820387270
MESH:D009472 Neuronal Ceroid-Lipofuscinoses Fenretinide 5.0516303764
MESH:D009503 Neutropenia Mustard Gas 3.4016761898 7688884
MESH:D052556 Niemann-Pick Disease, Type C Clofibrate 4.339802331
MESH:D009765 Obesity pirinixic acid 1.6320558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 12.0016049721 12819281
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 12.0016049721
MESH:D009784 Occupational Diseases 4-amino-2,6-dinitrotoluene 12.0014694615
MESH:D010018 Osteomalacia Phenobarbital 3.7417016548
MESH:D012516 Osteosarcoma Doxorubicin 3.6115930896
MESH:D010051 Ovarian Neoplasms Arsenic 19.1517306315
MESH:D010051 Ovarian Neoplasms arsenic trioxide 19.1512452020 19769630 16624393
MESH:D010051 Ovarian Neoplasms Estradiol 19.1519401270
MESH:D010051 Ovarian Neoplasms Fenretinide 19.1516133793
MESH:D010051 Ovarian Neoplasms Progesterone 19.1517393432 16525653
MESH:D010051 Ovarian Neoplasms sodium arsenite 19.1517306315 15276417
MESH:D010051 Ovarian Neoplasms Tretinoin 19.1516936753
MESH:D010146 Pain Acetaminophen 4.9116870215
MESH:D010146 Pain Tretinoin 4.9116870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 20.6915580305
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 20.6916540662
MESH:D010190 Pancreatic Neoplasms Ethanol 20.6912384795
MESH:D010190 Pancreatic Neoplasms Fenretinide 20.6915580305
MESH:D010190 Pancreatic Neoplasms Phenobarbital 20.6916965848
MESH:D010190 Pancreatic Neoplasms Tetradecanoylphorbol Acetate 20.6915976015
MESH:D010190 Pancreatic Neoplasms Tretinoin 20.6915976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.1111578682
MESH:D010212 Papilloma Tetradecanoylphorbol Acetate 3.6918922899 12065085 8330346 18404319
MESH:D010235 Paraganglioma arsenic trioxide 3.5819927285
MESH:D010382 Peliosis Hepatis 1-Naphthylisothiocyanate 11.6720133375
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 11.6712520081
MESH:D010391 Pemphigoid, Bullous Tetracycline 4.7911026799
MESH:D010523 Peripheral Nervous System Diseases Arsenic 3.5916093927
MESH:D016491 Peripheral Vascular Diseases Arsenic 4.3616905509 6392382 15371236
MESH:D003557 Phyllodes Tumor Doxorubicin 4.5217983394
MESH:D010900 Pituitary Diseases Diethylstilbestrol 4.5314722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 4.0615687265 16977796
MESH:D010954 Plasmacytoma Selenium 4.2515087411
MESH:D010997 Pleural Neoplasms Doxorubicin 4.5217638057
MESH:D011041 Poisoning Mustard Gas 3.2315727166
MESH:D017499 Porokeratosis alitretinoin 5.3616144296
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 2.9618163543
MESH:D011230 Precancerous Conditions Diethylnitrosamine 7.322563599
MESH:D011230 Precancerous Conditions Phenobarbital 7.322563599
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 18.1517184923
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 18.1511118676 11399792 11896295 11222880
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 18.1520603192
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 18.1518220299 18042343 19015723
MESH:D017096 Prion Diseases Tetracycline 4.7910903871
MESH:D011469 Prostatic Diseases vinclozolin 4.3118220299
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.3220887781
MESH:D011471 Prostatic Neoplasms Arsenic 2.6316140617
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.6319131511
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.6317292933
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 2.6317136230 15846301 15046698
MESH:D011471 Prostatic Neoplasms Doxorubicin 2.6315749863 15897917 16888761 16729912 16868541 18437689
MESH:D011471 Prostatic Neoplasms Estradiol 2.6316740699
MESH:D011471 Prostatic Neoplasms Fenretinide 2.6317024972
MESH:D011471 Prostatic Neoplasms Nevirapine 2.6319152342
MESH:D011471 Prostatic Neoplasms sodium arsenite 2.6316039940
MESH:D011472 Prostatitis vinclozolin 4.3118629315
MESH:D011507 Proteinuria Arsenic 7.3621343184
MESH:D011507 Proteinuria Tretinoin 7.3616636307
MESH:D011537 Pruritus Ethinyl Estradiol 7.4615861022 16919318
MESH:D011537 Pruritus Mustard Gas 7.4618058305
MESH:D019310 Pseudolymphoma Phenobarbital 10.0712752131
MESH:D019310 Pseudolymphoma Valproic Acid 10.0711422049 12752131
MESH:D011625 Pterygium Tretinoin 4.1716723453
MESH:D011658 Pulmonary Fibrosis Mustard Gas 2.6617720292 17266442 17620002 17894541 10334151
MESH:D051437 Renal Insufficiency Doxorubicin 3.6117922066
MESH:D015427 Reperfusion Injury pirinixic acid 2.0519058328
MESH:D012127 Respiratory Distress Syndrome, Newborn Vitamin A 5.1816877224
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.2418990726
MESH:D012162 Retinal Degeneration Fenretinide 3.9216303925
MESH:D012208 Rhabdomyosarcoma Tretinoin 8.9416283617 16116481
MESH:D012208 Rhabdomyosarcoma Valproic Acid 8.9419155313
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.6018045962
MESH:D012509 Sarcoma Doxorubicin 3.4418313854 15625365 17710206 16767912 17203757 15675481
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 8.3116646077
MESH:D012512 Sarcoma, Ewing's Doxorubicin 8.3116326096 14601052
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.1717846226
MESH:D012559 Schizophrenia Valproic Acid 1.9715737665 19110320
MESH:D012640 Seizures 2,4-dinitrotoluene 13.8618551238
MESH:D012640 Seizures 2,6-dinitrotoluene 13.8618551238
MESH:D012640 Seizures Ethanol 13.869754883
MESH:D012640 Seizures Phenobarbital 13.863137016 4039156 16876388 11442880
MESH:D012640 Seizures Valproic Acid 13.863137016 17978042 11044598 15475178 1511512 14763951 11738929 16876388
MESH:D003294 Seizures, Febrile Phenobarbital 4.206407741
MESH:D012871 Skin Diseases Arsenic 9.7219834688 16702368 16353154 17453740 18709164 17548696 15952646 17050553 16759981 17938729 6392382
MESH:D012871 Skin Diseases monomethylarsonic acid 9.7221378128
MESH:D012871 Skin Diseases Mustard Gas 9.7212880345 16961503 15451306
MESH:D012871 Skin Diseases Vitamin A 9.7218709164
MESH:D012878 Skin Neoplasms Arsenic 26.1517050553 17029826 16251483 17976673 19538983 15504454
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 26.1519755658 10029692
MESH:D012878 Skin Neoplasms Doxorubicin 26.1515692506
MESH:D012878 Skin Neoplasms Fenretinide 26.1516467112
MESH:D012878 Skin Neoplasms sodium arsenite 26.1518572023 19524636
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 26.1516192470
MESH:D012878 Skin Neoplasms Tetradecanoylphorbol Acetate 26.1511807781 8985016 12065085 8330346 18404319
MESH:D012878 Skin Neoplasms Tretinoin 26.1516467112
MESH:D055752 Small Cell Lung Carcinoma ABT-737 6.4919010845
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 3.9617203757 15625365 16767912
MESH:D013088 Spermatocele Diethylstilbestrol 9.6016709447 16002989
MESH:D013088 Spermatocele Ethinyl Estradiol 9.6016709447
MESH:D013119 Spinal Cord Injuries Progesterone 3.6616503802 15862959
MESH:D016135 Spinal Dysraphism sodium arsenite 7.9012854658
MESH:D016135 Spinal Dysraphism Valproic Acid 7.9019490988
MESH:D013158 Splenic Diseases Dimethylnitrosamine 4.6312587719
MESH:D013226 Status Epilepticus Valproic Acid 3.9012833885
MESH:D013272 Stomach Diseases beta Carotene 4.4717638125
MESH:D013274 Stomach Neoplasms arsenic trioxide 7.0917007042
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 7.0920155912 2093021
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 7.0918456281
MESH:D013274 Stomach Neoplasms Dimethylnitrosamine 7.0916033868
MESH:D013274 Stomach Neoplasms Ethanol 7.0918456281
MESH:D013274 Stomach Neoplasms Tretinoin 7.0917261132
MESH:D013276 Stomach Ulcer beta Carotene 6.0012500499
MESH:D013276 Stomach Ulcer Ethanol 6.009562338 16755016 11906479 9211565 17189318 17918041
MESH:D013375 Substance Withdrawal Syndrome Ethanol 3.719754883
MESH:D013921 Thrombocytopenia 1-Naphthylisothiocyanate 4.2120133375
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.0411994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.6215669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.2612697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 17.3219014326
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 17.327505956
MESH:D013964 Thyroid Neoplasms Doxorubicin 17.3217909728 16010429
MESH:D013964 Thyroid Neoplasms Phenobarbital 17.321399818
MESH:D013964 Thyroid Neoplasms Tretinoin 17.3216026305 17045167
MESH:D013978 Tibial Fractures Estradiol 4.0519048282
MESH:D014062 Tongue Neoplasms Tretinoin 3.2416051514
MESH:D016171 Torsades de Pointes arsenic trioxide 3.3415213294
MESH:D014178 Translocation, Genetic Valproic Acid 4.5917262798
MESH:D014376 Tuberculosis Tretinoin 2.8116040207
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 3.903119515
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 31.2516049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 31.2516049721
MESH:D001749 Urinary Bladder Neoplasms Arsenic 31.2519322015 19429237 17976673 15987713 11144890 17306315 18640142
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 31.2512845720 20435036 11780464 12973940
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 31.2517053015
MESH:D001749 Urinary Bladder Neoplasms Cacodylic Acid 31.2515537745
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 31.2517306315 16452187 16712894
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 31.2517653716
MESH:D001749 Urinary Bladder Neoplasms Fenretinide 31.2516720286
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 31.2517306315 11723127 16452187 16712894
MESH:D014564 Urogenital Abnormalities Valproic Acid 4.038888407
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 9.9110091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 9.9110091137
MESH:D014581 Urticaria Acetaminophen 2.4110982225
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 18.1816175088
MESH:D002583 Uterine Cervical Neoplasms Fenretinide 18.1816154183
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 18.1811813266
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 18.1816129372
MESH:D014591 Uterine Diseases Diethylstilbestrol 4.5314652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 7.5015809267 16690809
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 7.5014692618
MESH:D014604 Uveal Neoplasms Tretinoin 3.9716752155
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 3.8316002989 16513791
MESH:D014652 Vascular Diseases Arsenic 9.7717056641
MESH:D014652 Vascular Diseases sodium arsenite 9.7717056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 3.9612125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 2.9814671159 15869587
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 3.6117678736 16364871 17334414 17638931
MESH:D014802 Vitamin A Deficiency Vitamin A 4.7016175781 16960172 16146918
MESH:D014820 Vitiligo Tretinoin 3.4616761959
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.6115886252
MESH:D009396 Wilms Tumor Tretinoin 3.4316287080
Pathway ID Pathway Name
KEGG:05130 Pathogenic Escherichia coli infection
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Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018