Gene Symbol:	INSC ( - )
Gene Full Name:	inscuteable homolog (Drosophila)
Band:	11p15.2
Quick Links	Entrez ID:387755; OMIM: 610668; Uniprot ID:INSC_HUMAN; ENSEMBL ID: ENSG00000188487; HGNC ID: 33116
Relate to Another Database:	SFARIGene; denovo-db

Chemical ID	Chemical Name	Interaction	Interaction Action	Publication
D000082	Acetaminophen	Acetaminophen affects the expression of INSC mRNA	affects expression	17562736
D015123	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide affects the expression of INSC mRNA	affects expression	20382639
D010634	Phenobarbital	Phenobarbital results in decreased expression of INSC mRNA	decreases expression	19270015

Disease ID	Disease Name	Inference Chemical Name	Inference Score	Publication
MESH:D000014	Abnormalities, Drug-Induced	Phenobarbital	4.18	6195326
MESH:D018248	Adenoma, Liver Cell	Phenobarbital	4.71	17620307
MESH:D000799	Angioedema	Acetaminophen	4.71	10982225
MESH:D001321	Autistic Disorder	Acetaminophen	1.39	18445737
MESH:D006528	Carcinoma, Hepatocellular	Acetaminophen	3.03	3084413
MESH:D006528	Carcinoma, Hepatocellular	Phenobarbital	3.03	1701930 6705139 20935162 17173139 20007298
MESH:D002386	Cataract	Acetaminophen	2.81	10977129
MESH:D002471	Cell Transformation, Neoplastic	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide	3.01	20889678
MESH:D002493	Central Nervous System Diseases	Phenobarbital	4.90	4080065
MESH:D056486	Drug-Induced Liver Injury	Acetaminophen	1.68	12153990 17522070 11743745 11287661 19164858 16227642 12392966 19420014 11529661 15968718 11739529 12705907 19370779 17906064 17562736 14986274 12594235 19739265 10663392 19085960 14550746 11421492 18713872 12958197 16485898 10915739 16393943 19416960 12540782 18071297 2444490 16177239 19923254 11834606 15619225 16081117 10774834 11461765 16781746 16109766 14725611
MESH:D056487	Drug-Induced Liver Injury, Chronic	Acetaminophen	4.96	19426721
MESH:D004421	Dystonia	Phenobarbital	4.53	1851702
MESH:D004831	Epilepsies, Myoclonic	Phenobarbital	4.76	3659116
MESH:D004828	Epilepsies, Partial	Phenobarbital	4.74	3922381 11558140
MESH:D004827	Epilepsy	Phenobarbital	3.08	20417680
MESH:D004832	Epilepsy, Absence	Phenobarbital	3.96	6401628
MESH:D017029	Epilepsy, Complex Partial	Phenobarbital	4.90	7750514
MESH:D004830	Epilepsy, Tonic-Clonic	Phenobarbital	4.76	3659116
MESH:D004938	Esophageal Neoplasms	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide	2.15	20426865
MESH:D005756	Gastritis	Acetaminophen	4.54	16983495
MESH:D006529	Hepatomegaly	Phenobarbital	4.13	16109766
MESH:D006930	Hyperalgesia	Acetaminophen	3.06	16870215
MESH:D007674	Kidney Diseases	Acetaminophen	2.42	15629191 12587719
MESH:D008103	Liver Cirrhosis	Phenobarbital	3.10	21047994
MESH:D008107	Liver Diseases	Acetaminophen	4.22	16611625 12969438 16610002 19460945 11587558 19014921 12587719 19784758
MESH:D008107	Liver Diseases	Phenobarbital	4.22	19363144
MESH:D017114	Liver Failure, Acute	Acetaminophen	3.68	16871587 17185352
MESH:D008113	Liver Neoplasms	Phenobarbital	2.43	19812893 15975961 19073162 19482888 8742319 21047994
MESH:D008114	Liver Neoplasms, Experimental	Phenobarbital	2.95	6150874 17172636 18308698 1399818 2563599
MESH:D008546	Melanoma, Experimental	Acetaminophen	4.22	19513568
MESH:D020191	Myoclonic Epilepsies, Progressive	Phenobarbital	5.22	17484760
MESH:D019636	Neurodegenerative Diseases	Acetaminophen	3.26	18514411
MESH:D010018	Osteomalacia	Phenobarbital	5.11	17016548
MESH:D010146	Pain	Acetaminophen	2.77	16870215
MESH:D010190	Pancreatic Neoplasms	Phenobarbital	2.61	16965848
MESH:D011230	Precancerous Conditions	Phenobarbital	4.04	2563599
MESH:D019310	Pseudolymphoma	Phenobarbital	5.36	12752131
MESH:D012640	Seizures	Phenobarbital	2.97	16876388 3137016 4039156 11442880
MESH:D003294	Seizures, Febrile	Phenobarbital	5.56	6407741
MESH:D013964	Thyroid Neoplasms	Phenobarbital	3.39	1399818
MESH:D014581	Urticaria	Acetaminophen	3.50	10982225

AutismKB 2.0

Annotation Detail for INSC

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics