Gene Symbol:	CAPN8 ( nCL-2 )
Gene Full Name:	calpain 8
Band:	1q41
Quick Links	Entrez ID:388743; OMIM: NA; Uniprot ID:CAN8_HUMAN; ENSEMBL ID: ENSG00000203697; ENSG00000184445; HGNC ID: 1485
Relate to Another Database:	SFARIGene; denovo-db

Chemical ID	Chemical Name	Interaction	Interaction Action	Publication
D000082	Acetaminophen	CAPN8 gene polymorphism results in increased susceptibility to Acetaminophen	increases response to substance	19416960
D000643	Ammonium Chloride	Ammonium Chloride affects the expression of CAPN8 mRNA	affects expression	16483693
C055494	caffeic acid phenethyl ester	caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in decreased expression of CAPN8 mRNA]	decreases expression\|decreases reaction	20360939
D004052	Diethylnitrosamine	caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in decreased expression of CAPN8 mRNA]	decreases expression\|decreases reaction	20360939
D004052	Diethylnitrosamine	Diethylnitrosamine results in decreased expression of CAPN8 mRNA	decreases expression	20360939
D005419	Flavonoids	Flavonoids results in decreased expression of CAPN8 mRNA	decreases expression	18035473

Disease ID	Disease Name	Inference Chemical Name	Inference Score	Publication
MESH:D000138	Acidosis	Ammonium Chloride	4.10	18287403
MESH:D000236	Adenoma	Diethylnitrosamine	3.03	10737359 6695378
MESH:D018248	Adenoma, Liver Cell	Diethylnitrosamine	4.44	16434500 19061943 17162532 17620307 18056438 19052882
MESH:D000799	Angioedema	Acetaminophen	4.45	10982225
MESH:D001321	Autistic Disorder	Acetaminophen	1.40	18445737
MESH:D001943	Breast Neoplasms	Diethylnitrosamine	2.19	17474063
MESH:D006528	Carcinoma, Hepatocellular	Acetaminophen	2.98	3084413
MESH:D006528	Carcinoma, Hepatocellular	Diethylnitrosamine	2.98	16807293 17055752 19539802 19519916 11831363 19919837 16779866 10737359 21159647 16878318 18785209 3581430 20007298 20101231 19822196 16540662 18393292 17428255 20524982 19107877 19701751 18494052 19052882 20084675 16569478 19394651 17978847 19335982 18210153 16830150 18506893 16681979 20727157 18691550 19171122 18665156 16935385 18978308 17138121 20432363 20214788 17162532 17761372 19383236 3084413 19418558 19208518 20935162 16288022 10672840 17173139 18056438 16328049 16698587 16502159 20512989 18971187 20514400 18788625
MESH:D002386	Cataract	Acetaminophen	2.77	10977129
MESH:D002471	Cell Transformation, Neoplastic	Diethylnitrosamine	3.09	2727394 21159647 7505956 17174075
MESH:D018281	Cholangiocarcinoma	Diethylnitrosamine	4.01	19052882
MESH:D003924	Diabetes Mellitus, Type 2	Diethylnitrosamine	2.25	20387270
MESH:D056486	Drug-Induced Liver Injury	Acetaminophen	4.03	19164858 10774834 12958197 14550746 17522070 15619225 11421492 12153990 17562736 12392966 14986274 12540782 11834606 11529661 19923254 19420014 2444490 10663392 12594235 11743745 19370779 16177239 16109766 16081117 16393943 10915739 16227642 18713872 16485898 16781746 19085960 19416960 11287661 11739529 15968718 12705907 14725611 19739265 18071297 11461765 17906064
MESH:D056486	Drug-Induced Liver Injury	Diethylnitrosamine	4.03	19107877
MESH:D056487	Drug-Induced Liver Injury, Chronic	Acetaminophen	4.71	19426721
MESH:D004931	Esophageal Achalasia	Diethylnitrosamine	5.73	16302075
MESH:D005234	Fatty Liver	Diethylnitrosamine	3.56	20387270 21071580
MESH:D005756	Gastritis	Acetaminophen	4.29	16983495
MESH:D006930	Hyperalgesia	Acetaminophen	2.99	16870215
MESH:D007249	Inflammation	Diethylnitrosamine	5.73	18785209
MESH:D007249	Inflammation	Flavonoids	5.73	17296493
MESH:D007414	Intestinal Neoplasms	caffeic acid phenethyl ester	4.93	10783313
MESH:D007674	Kidney Diseases	Acetaminophen	6.86	15629191 12587719
MESH:D007674	Kidney Diseases	caffeic acid phenethyl ester	6.86	15369732
MESH:D015473	Leukemia, Promyelocytic, Acute	caffeic acid phenethyl ester	4.21	16766008
MESH:D008103	Liver Cirrhosis	Diethylnitrosamine	2.99	18665156 18407596 20032147 19638242 18522880
MESH:D008107	Liver Diseases	Acetaminophen	4.15	12969438 16610002 16611625 19460945 12587719 19014921 19784758 11587558
MESH:D008107	Liver Diseases	Diethylnitrosamine	4.15	17034775
MESH:D017114	Liver Failure, Acute	Acetaminophen	3.58	16871587 17185352
MESH:D008113	Liver Neoplasms	Diethylnitrosamine	2.34	19073162 19833225 19427195 19256749 16942905 19850985 19426721 20583210 19690152 19996281 21047994 18978307 12112319 21167192 19499222 19551842 18648771 20434301 18754104 9163691 18977376 19255062 19294768 15885732 21278145 20501860 18644402 20118626 19812893 2422723 15175105 21071580 12771043 19090486 20137499 20492335 19254457 10737359 20452335 20405173 20101389 2862719 19638242 19642983
MESH:D008114	Liver Neoplasms, Experimental	Diethylnitrosamine	2.83	18775883 2563599 18544905 16842330 18079962 19009564 19126423 19539802 18164116 19519916 18253720 17174075 3124819 18308698 16267830 9362446 21159647 18093689 19004024 17942915 18282651 17854601
MESH:D008175	Lung Neoplasms	Diethylnitrosamine	1.76	6695378 20970405 21163286 20512841
MESH:D008546	Melanoma, Experimental	Acetaminophen	4.05	19513568
MESH:D009362	Neoplasm Metastasis	Diethylnitrosamine	2.68	3581430 9029167
MESH:D019636	Neurodegenerative Diseases	Acetaminophen	9.22	18514411
MESH:D019636	Neurodegenerative Diseases	Diethylnitrosamine	9.22	20387270
MESH:D009461	Neurologic Manifestations	Diethylnitrosamine	5.73	20387270
MESH:D010146	Pain	Acetaminophen	2.69	16870215
MESH:D010190	Pancreatic Neoplasms	Diethylnitrosamine	2.52	16540662
MESH:D011230	Precancerous Conditions	Diethylnitrosamine	3.88	2563599
MESH:D013274	Stomach Neoplasms	Diethylnitrosamine	1.76	18456281
MESH:D013964	Thyroid Neoplasms	Diethylnitrosamine	3.25	7505956
MESH:D014581	Urticaria	Acetaminophen	3.38	10982225

AutismKB 2.0

Annotation Detail for CAPN8

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics