Annotation Detail for MUSTN1

Basic Information
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| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| C023514 |
2,6-dinitrotoluene |
2,6-dinitrotoluene results in increased expression of MUSTN1 mRNA | increases expression | 20406850
|
| D000082 |
Acetaminophen |
Acetaminophen affects the expression of MUSTN1 mRNA | affects expression | 17562736
|
| D003345 |
Corticosterone |
Corticosterone results in increased expression of MUSTN1 mRNA | increases expression | 15755911
|
| D007657 |
Ketone Bodies |
Ketone Bodies results in decreased expression of MUSTN1 mRNA | decreases expression | 16807920
|
| D010656 |
Phenylephrine |
Phenylephrine results in increased expression of MUSTN1 mRNA | increases expression | 18158353
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000799 |
Angioedema |
|
Acetaminophen |
4.45 | 10982225 |
| MESH:D001145 |
Arrhythmias, Cardiac |
|
Phenylephrine |
4.46 | 17460149 |
| MESH:D001321 |
Autistic Disorder |
|
Acetaminophen |
1.40 | 18445737 |
| MESH:D001919 |
Bradycardia |
|
Phenylephrine |
5.08 | 15306635 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
2,6-dinitrotoluene |
2.95 | 16705839 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
Acetaminophen |
2.95 | 3084413 |
| MESH:D006332 |
Cardiomegaly |
|
Phenylephrine |
3.70 | 15728586 11179087 17124262 17287366 11754973 16170337 |
| MESH:D002386 |
Cataract |
|
Acetaminophen |
2.77 | 10977129 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
2,6-dinitrotoluene |
3.00 | 6135515 |
| MESH:D003490 |
Cyanosis |
|
2,6-dinitrotoluene |
4.50 | 18551238 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
2,6-dinitrotoluene |
3.99 | 18551238 21346803 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Acetaminophen |
3.99 | 19370779 19085960 18713872 11287661 12153990 17522070 11739529 12705907 12540782 19420014 14550746 11421492 2444490 19739265 17562736 16109766 19923254 16177239 19416960 16227642 10774834 16781746 16485898 17906064 11743745 11834606 10663392 12958197 11461765 16081117 19164858 10915739 18071297 15968718 16393943 14986274 12594235 14725611 11529661 15619225 12392966 |
| MESH:D056487 |
Drug-Induced Liver Injury, Chronic |
|
Acetaminophen |
4.71 | 19426721 |
| MESH:D005756 |
Gastritis |
|
Acetaminophen |
4.29 | 16983495 |
| MESH:D006930 |
Hyperalgesia |
|
Acetaminophen |
2.99 | 16870215 |
| MESH:D006973 |
Hypertension |
|
Phenylephrine |
3.18 | 8949925 12717712 |
| MESH:D006984 |
Hypertrophy |
|
Phenylephrine |
4.93 | 12791704 18502941 |
| MESH:D007674 |
Kidney Diseases |
|
Acetaminophen |
2.38 | 15629191 12587719 |
| MESH:D007680 |
Kidney Neoplasms |
|
2,6-dinitrotoluene |
3.28 | 16705839 |
| MESH:D008107 |
Liver Diseases |
|
Acetaminophen |
1.69 | 19460945 16611625 19784758 19014921 12969438 11587558 16610002 12587719 |
| MESH:D017114 |
Liver Failure, Acute |
|
Acetaminophen |
3.58 | 17185352 16871587 |
| MESH:D008113 |
Liver Neoplasms |
|
2,6-dinitrotoluene |
2.25 | 7678174 |
| MESH:D008114 |
Liver Neoplasms, Experimental |
|
2,6-dinitrotoluene |
2.74 | 2876784 2876786 6135515 |
| MESH:D008325 |
Mammary Neoplasms, Experimental |
|
Corticosterone |
3.83 | 12807724 |
| MESH:D008546 |
Melanoma, Experimental |
|
Acetaminophen |
4.05 | 19513568 |
| MESH:D009336 |
Necrosis |
|
2,6-dinitrotoluene |
4.40 | 7678174 18551238 |
| MESH:D019636 |
Neurodegenerative Diseases |
|
Acetaminophen |
3.18 | 18514411 |
| MESH:D009784 |
Occupational Diseases |
|
2,6-dinitrotoluene |
3.78 | 16049721 |
| MESH:D010146 |
Pain |
|
Acetaminophen |
2.69 | 16870215 |
| MESH:D012640 |
Seizures |
|
2,6-dinitrotoluene |
2.76 | 18551238 |
| MESH:D012852 |
Sinusitis |
|
Phenylephrine |
5.24 | 7327846 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
2,6-dinitrotoluene |
2.40 | 16049721 |
| MESH:D014571 |
Urologic Neoplasms |
|
2,6-dinitrotoluene |
4.86 | 10091137 |
| MESH:D014581 |
Urticaria |
|
Acetaminophen |
3.38 | 10982225 |