AutismKB 2.0

Annotation Detail for LAMC2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:LAMC2 ( B2T,BM600,CSF,EBR2,EBR2A,LAMB2T,LAMNB2,MGC138491,MGC141938 )
Gene Full Name: laminin, gamma 2
Band: 1q25.3
Quick LinksEntrez ID:3918; OMIM: 150292; Uniprot ID:LAMC2_HUMAN; ENSEMBL ID: ENSG00000058085; HGNC ID: 6493
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa05146Amoebiasis
hsa05145Toxoplasmosis
hsa05222Small cell lung cancer
hsa04512ECM-receptor interaction
hsa04510Focal adhesion
hsa05200Pathways in cancer
Pathway IDPathway Name
Cell junction organization
No data
No data
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1990Skin disease, Genetic
1934Cancer
No data
No data
Desease Name
Epidermolysis bullosa, junctional, non-Herlitz type
Epidermolysis bullosa, junctional, Herlitz type
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C025205 1,10-phenanthroline 1,10-phenanthroline inhibits the reaction [Mustard Gas results in increased degradation of LAMC2 protein]decreases reaction|increases degradation 18095945
C003614 4-toluenesulfonyl fluoride 4-toluenesulfonyl fluoride inhibits the reaction [Mustard Gas results in increased degradation of LAMC2 protein]decreases reaction|increases degradation 18095945
D000082 Acetaminophen Acetaminophen affects the expression of LAMC2 mRNAaffects expression 17562736
D000643 Ammonium Chloride Ammonium Chloride affects the expression of LAMC2 mRNAaffects expression 16483693
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in increased expression of LAMC2 mRNAincreases expression 15336504
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in increased expression of LAMC2 mRNAincreases expression 15003993
D019259 Lamivudine [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of LAMC2 mRNAaffects cotreatment|increases expression 16931933
D019259 Lamivudine [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of LAMC2 mRNAaffects cotreatment|increases expression 16931933
D004041 Dietary Fats Dietary Fats results in decreased expression of LAMC2 mRNAdecreases expression 18042831
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of LAMC2 mRNAincreases expression 15289156
D004958 Estradiol [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of LAMC2 mRNAaffects cotreatment|decreases expression 19619570
D004958 Estradiol Estradiol results in increased expression of LAMC2 mRNAincreases expression 19619570
D004958 Estradiol Estradiol results in increased expression of LAMC2 mRNAincreases expression 15289156
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of LAMC2 mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of LAMC2 mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of LAMC2 mRNAaffects cotreatment|increases expression 17942748
D019833 Genistein Genistein results in decreased expression of LAMC2 mRNAdecreases expression 14871586
D019833 Genistein Genistein results in increased expression of LAMC2 mRNAincreases expression 15289156
D019469 Indinavir [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of LAMC2 mRNAaffects cotreatment|increases expression 16931933
D008070 Lipopolysaccharides Lipopolysaccharides results in decreased expression of LAMC2 mRNAdecreases expression 12057914
C032881 lysophosphatidic acid lysophosphatidic acid results in increased expression of LAMC2 mRNAincreases expression 15541073
D008244 Lysophosphatidylcholines Lysophosphatidylcholines results in increased expression of LAMC2 mRNAincreases expression 15541073
D008466 Mechlorethamine Mechlorethamine results in decreased expression of LAMC2 proteindecreases expression 9504665
D008466 Mechlorethamine Mechlorethamine results in increased degradation of LAMC2 proteinincreases degradation 18095945
D015735 Mifepristone Mifepristone results in increased expression of LAMC2 mRNAincreases expression 17584828
D009151 Mustard Gas 1,10-phenanthroline inhibits the reaction [Mustard Gas results in increased degradation of LAMC2 protein]decreases reaction|increases degradation 18095945
D009151 Mustard Gas 4-toluenesulfonyl fluoride inhibits the reaction [Mustard Gas results in increased degradation of LAMC2 protein]decreases reaction|increases degradation 18095945
D009151 Mustard Gas Mustard Gas results in decreased expression of LAMC2 proteindecreases expression 9504665
D009151 Mustard Gas Mustard Gas results in increased degradation of [LAMA3 protein binds to LAMB3 protein binds to LAMC2 protein]affects binding|increases degradation 18095945
D009151 Mustard Gas Mustard Gas results in increased degradation of LAMC2 proteinincreases degradation 18095945
18300329
D009151 Mustard Gas Mustard Gas results in decreased expression of LAMC2 proteindecreases expression 9302645
C022838 nickel chloride nickel chloride results in decreased expression of LAMC2 mRNAdecreases expression 12839937
C041786 palm oil palm oil results in decreased expression of LAMC2 mRNAdecreases expression 18042831
D010656 Phenylephrine Phenylephrine results in increased expression of LAMC2 mRNAincreases expression 18158353
D015575 Roxithromycin Roxithromycin results in decreased expression of LAMC2 proteindecreases expression 14687228
D019258 Saquinavir [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of LAMC2 mRNAaffects cotreatment|increases expression 16931933
C060506 sphingosine 1-phosphate sphingosine 1-phosphate results in increased expression of LAMC2 mRNAincreases expression 15541073
D013629 Tamoxifen Tamoxifen affects the expression of LAMC2 mRNAaffects expression 17555576
D013749 Tetrachlorodibenzodioxin [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of LAMC2 mRNAaffects cotreatment|decreases expression 19619570
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of LAMC2 mRNAincreases expression 19619570
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of LAMC2 mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of LAMC2 mRNAincreases expression 17586704
C117153 tetracycline CMT-8 tetracycline CMT-8 results in increased expression of LAMC2 proteinincreases expression 11983005
D014212 Tretinoin Tretinoin results in increased expression of LAMC2 mRNAincreases expression 17138961
C025643 vinclozolin vinclozolin affects the expression of LAMC2 mRNAaffects expression 19015723
D015215 Zidovudine [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of LAMC2 mRNAaffects cotreatment|increases expression 16931933
D015215 Zidovudine [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of LAMC2 mRNAaffects cotreatment|increases expression 16931933
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.2614745880
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.5715322242 11752688 14514962
MESH:D000138 Acidosis Ammonium Chloride 3.2818287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.6617505938
MESH:D000163 Acquired Immunodeficiency Syndrome Zidovudine 4.559612607
MESH:D055371 Acute Lung Injury Lipopolysaccharides 3.7818653653 11850527
MESH:D000230 Adenocarcinoma Estradiol 6.6311473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 6.6314692618
MESH:D000230 Adenocarcinoma Genistein 6.6311473722
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 3.1016835633
MESH:D000505 Alopecia Tretinoin 3.4015955085
MESH:D000686 Amyloidosis Diethylstilbestrol 4.2115469931
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.7111748828
MESH:D000799 Angioedema Acetaminophen 3.5610982225
MESH:D001008 Anxiety Disorders vinclozolin 3.4219015723
MESH:D001145 Arrhythmias, Cardiac Phenylephrine 3.8717460149
MESH:D001161 Arteriosclerosis Dietary Fats 9.0015238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 9.0011256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 6.6415885639
MESH:D001169 Arthritis, Experimental Tretinoin 6.6416412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.2016292516
MESH:D001249 Asthma Mustard Gas 4.6810378619
MESH:D001249 Asthma Tretinoin 4.6816456186
MESH:D001321 Autistic Disorder Acetaminophen 1.4518445737
MESH:D001471 Barrett Esophagus Tretinoin 4.1416935849
MESH:D001768 Blister Mustard Gas 4.8819167455
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 8.1112125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 8.1116206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.5115340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.5915746008
MESH:D001919 Bradycardia Phenylephrine 4.2615306635
MESH:D001943 Breast Neoplasms Dietary Fats 3.5820435547
MESH:D001943 Breast Neoplasms Diethylstilbestrol 3.5815324884 17129689
MESH:D001943 Breast Neoplasms Estradiol 3.5819861407 17289903 16675129 12948864 14630087 17261762 17018787 18497071
MESH:D001943 Breast Neoplasms Genistein 3.5816873071 17200150 16541309
MESH:D001943 Breast Neoplasms Tamoxifen 3.5819487384 19142967 17242785 18815881 16873071 18855134 19288272 17893378 19244106 20135344 20005174 15668708 19103187 18629630 19115204 18351453 18984771 16818667 19410462 19011961 19289846 19066611 19059307 19084267 21152245 11161223 17261762 16202921 18425577 19155303 18821012 20544844 16273361 19189212 17440819 19189210 20390343 19221464 19200415 15565566 18997820 21138602 20065188 17049068 20859285
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 3.5820435547
MESH:D001943 Breast Neoplasms Tretinoin 3.5816443354 16166294 16873071
MESH:D001989 Bronchiolitis Obliterans Mustard Gas 4.8815286001
MESH:D029481 Bronchitis, Chronic Mustard Gas 4.6917687719 10378619
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.3116813970
MESH:D002057 Burns, Chemical Mechlorethamine 5.959625245
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.1816111702
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.5816835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.2319066611
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.8716168501
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 10.753084413
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 10.7516924424 15948411
MESH:D006528 Carcinoma, Hepatocellular Estradiol 10.7516924424
MESH:D006528 Carcinoma, Hepatocellular Genistein 10.7516924424
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 10.7516924424
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 10.751917145
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 2.2116051514 16096774
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.3717572228
MESH:D006332 Cardiomegaly Phenylephrine 6.3717124262 11754973 15728586 11179087 16170337 17287366
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 6.3718850075 18670907 16120746
MESH:D002318 Cardiovascular Diseases Genistein 3.1116332659
MESH:D002386 Cataract Acetaminophen 6.6810977129
MESH:D002386 Cataract Tretinoin 6.6817460283
MESH:D002471 Cell Transformation, Neoplastic Estradiol 2.5918566989
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.3116129372
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 2.9316835633
MESH:D002779 Cholestasis Ethinyl Estradiol 2.6716919318 16105132 15861022 17681005 11677210 17110522 17333356
MESH:D002822 Choriocarcinoma Tretinoin 4.8716461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.3712621046 8697196 16354765 15340226 15668235
MESH:D002972 Cleft Palate Tretinoin 5.379407595
MESH:D003092 Colitis Tretinoin 3.4317035595
MESH:D003110 Colonic Neoplasms Genistein 2.2417182828
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.8317141729 14669216
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.3615322242 20055451 10048152
MESH:D019465 Craniofacial Abnormalities Tretinoin 2.369142499 9664655 9211117 17551590 8800419 10589399 16925845 14991402 9125849 9224671
MESH:D003456 Cryptorchidism Diethylstilbestrol 10.4816002989 12952375
MESH:D003456 Cryptorchidism vinclozolin 10.4814966744
MESH:D003457 Cryptosporidiosis Roxithromycin 6.6411362904
MESH:D003711 Demyelinating Diseases Tamoxifen 4.0919031437
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 4.0916647724
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.0917107852
MESH:D003928 Diabetic Nephropathies Estradiol 8.0619279558
MESH:D003928 Diabetic Nephropathies Tamoxifen 8.0619279558
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 3.2810915739 17906064 18071297 11461765 11287661 19739265 15619225 19416960 12153990 14986274 18713872 15968718 16393943 16177239 10774834 14725611 12705907 11421492 19923254 19085960 11529661 17522070 11743745 16781746 14550746 12958197 12540782 11834606 19370779 16081117 11739529 16109766 2444490 16227642 19164858 19420014 10663392 16485898 12392966 12594235 17562736
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 3.2820420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.8119426721
MESH:D004362 Drug Toxicity Lamivudine 12.6915040536
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 12.6911462148
MESH:D004362 Drug Toxicity Zidovudine 12.6915040536
MESH:D050171 Dyslipidemias Dietary Fats 3.2618367378
MESH:D004487 Edema Mustard Gas 6.0311402378 9260866 11428647 11428631
MESH:D004487 Edema Tetrachlorodibenzodioxin 6.0312711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 11.0015322242 16714409 18230668
MESH:D004489 Edema, Cardiac Tretinoin 11.0018230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 8.0612538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 8.0619031437
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 10.9616402032
MESH:D004714 Endometrial Hyperplasia Genistein 10.9616402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 21.4216804899 15700306
MESH:D016889 Endometrial Neoplasms Estradiol 21.4211473722 19148513 18566989
MESH:D016889 Endometrial Neoplasms Genistein 21.4211473722
MESH:D016889 Endometrial Neoplasms Tamoxifen 21.4219155303 20544844 17893378 16202921
MESH:D016889 Endometrial Neoplasms Tretinoin 21.4216569247
MESH:D004715 Endometriosis Mifepristone 8.3516134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 8.359294722 10568697
MESH:D019446 Endotoxemia Lipopolysaccharides 4.1215328337 17637181 15821434
OMIM:226700 EPIDERMOLYSIS BULLOSA, JUNCTIONAL, HERLITZ TYPE marker/mechanism
OMIM:226650 EPIDERMOLYSIS BULLOSA, JUNCTIONAL, NON-HERLITZ TYPE marker/mechanism
MESH:D004890 Erythema Mustard Gas 4.889357497
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 8.1511564622
MESH:D005124 Eye Abnormalities Tretinoin 8.1516938888 9664655
MESH:D005234 Fatty Liver Dietary Fats 16.7617967931 19004024 19551842 18296743
MESH:D005234 Fatty Liver Ethinyl Estradiol 16.7615345470
MESH:D005234 Fatty Liver Tamoxifen 16.7619224547 14986274
MESH:D005234 Fatty Liver Zidovudine 16.7618299183
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 7.6516534752 16611131 15751030 16513791 16002989
MESH:D052776 Female Urogenital Diseases Tamoxifen 7.6516709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.1811858732
MESH:D005334 Fever Lipopolysaccharides 3.779205823 11852909
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.2514745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 3.9019069698
MESH:D005355 Fibrosis Dietary Fats 13.1818296743
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 13.1820067830
MESH:D005355 Fibrosis Tretinoin 13.1817994277
MESH:D005756 Gastritis Acetaminophen 3.3916983495
MESH:D030342 Genetic Diseases, Inborn vinclozolin 4.6516973722
MESH:D005832 Genital Diseases, Male vinclozolin 5.0216417039
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 4.6716452187
MESH:D005909 Glioblastoma Genistein 6.6116598420
MESH:D005909 Glioblastoma Tretinoin 6.6117312396
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.3110696789
MESH:D006258 Head and Neck Neoplasms Tretinoin 3.0016096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.8716084493
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.0510048152 11294989
MESH:D006330 Heart Defects, Congenital Tretinoin 6.059664655 14991402
MESH:D006402 Hematologic Diseases Zidovudine 4.4512579204
MESH:D006463 Hemolytic-Uremic Syndrome Lipopolysaccharides 4.1416366002
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.0911000095
MESH:D006509 Hepatitis B Lamivudine 4.8517703166
MESH:D019694 Hepatitis B, Chronic Lamivudine 4.8515309715 15631357 12044531 16476009 15274664
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 2.6216120746 15340226 12621046
MESH:D006558 Herpes Genitalis Estradiol 4.7515709030
MESH:D015658 HIV Infections Indinavir 14.3111363243 15388451 11141242
MESH:D015658 HIV Infections Lamivudine 14.3117530837 11141242 20032539 9296927
MESH:D015658 HIV Infections Saquinavir 14.3111141242 15388451
MESH:D015658 HIV Infections Zidovudine 14.3120032539 11363243 11698656 17358032 11141242
MESH:D019584 Hot Flashes Estradiol 3.4717088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.7616354765 18606429 8697196 16959395 15340226
MESH:D006930 Hyperalgesia Acetaminophen 6.9016870215
MESH:D006930 Hyperalgesia Tretinoin 6.9016870215
MESH:D006937 Hypercholesterolemia Dietary Fats 3.3421332399
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.2916778211
MESH:D006949 Hyperlipidemias Dietary Fats 3.3621332399
MESH:D006965 Hyperplasia Diethylstilbestrol 4.1614722030 12960047
MESH:D006973 Hypertension Phenylephrine 4.948949925 12717712
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 4.9418670907 18850075
MESH:D006984 Hypertrophy Phenylephrine 4.3012791704 18502941
MESH:D007021 Hypospadias Diethylstilbestrol 10.3316002989
MESH:D007021 Hypospadias Ethinyl Estradiol 10.3316569931 16945680
MESH:D007246 Infertility Diethylstilbestrol 4.0915036965
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.2012013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 6.0517937319
MESH:D007248 Infertility, Male vinclozolin 6.0516467254
MESH:D007249 Inflammation Dietary Fats 18.0820412841
MESH:D007249 Inflammation Lipopolysaccharides 18.0817237260 17255318 12878042 17963957 9205823
MESH:D007249 Inflammation Mustard Gas 18.088975870 11428631 11428620 16001271 9260866 11428647 17524151 11402378 9357497
MESH:D007249 Inflammation Roxithromycin 18.0817524151
MESH:D007249 Inflammation Tamoxifen 18.0819457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 18.0812200463 12878042
MESH:D007333 Insulin Resistance Dietary Fats 6.7711836018 18457598
MESH:D007333 Insulin Resistance Estradiol 6.7716393666 16627594
MESH:D007410 Intestinal Diseases Tretinoin 3.4917994277
MESH:D019189 Iron Metabolism Disorders Lipopolysaccharides 4.3717255318
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 9.1016580747
MESH:D007569 Jaw Abnormalities Tretinoin 9.1015992940 17551590
MESH:D007674 Kidney Diseases Acetaminophen 5.3512587719 15629191
MESH:D007674 Kidney Diseases Estradiol 5.3515618244
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 15.9714681315 15003126 16762066
MESH:D007680 Kidney Neoplasms Estradiol 15.9715610895
MESH:D007680 Kidney Neoplasms Tamoxifen 15.9718625569
MESH:D007680 Kidney Neoplasms Zidovudine 15.9712579204
MESH:D007859 Learning Disorders Diethylstilbestrol 3.7917184923
MESH:D007938 Leukemia Genistein 5.9517468513 18980019
MESH:D007938 Leukemia Tretinoin 5.9517143497
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Zidovudine 4.1620370541
MESH:D007951 Leukemia, Myeloid Tretinoin 3.4516932348 16482212 19285840
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 2.0319850784 16294345 17596541
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 2.9719225113 16788101 19029980 17294898 17649720 16823087 16935935 17712046 17217047 17107899 12679006 17361223 17506722 16331271 16140955 19035177 17301526 15748426 17368321 9834237 16766008 16891316 19642359 19075265 17339181
MESH:D007970 Leukopenia Lipopolysaccharides 4.4215821434
MESH:D007984 Leydig Cell Tumor vinclozolin 4.4516417039
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.119224671
MESH:D008064 Lipidoses Tamoxifen 2.9617567588 15342952
MESH:D008103 Liver Cirrhosis Dietary Fats 2.7318296743
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 8.2514659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental Genistein 8.2517823541
MESH:D008106 Liver Cirrhosis, Experimental Lipopolysaccharides 8.2512878042
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 8.2518564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 8.2512878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 8.2516248980 18397230
MESH:D008107 Liver Diseases Acetaminophen 1.5619784758 16611625 19460945 16610002 12969438 11587558 19014921 12587719
MESH:D017114 Liver Failure, Acute Acetaminophen 2.9917185352 16871587
MESH:D008113 Liver Neoplasms Diethylstilbestrol 6.8115890375 16712894
MESH:D008113 Liver Neoplasms Tamoxifen 6.8116684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 6.8116984957
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 1.9412151625
MESH:D008171 Lung Diseases Mustard Gas 3.2618702808 18161513
MESH:D055370 Lung Injury Lipopolysaccharides 3.7421114838
MESH:D008175 Lung Neoplasms Mustard Gas 4.593148597 8781369
MESH:D008175 Lung Neoplasms Tamoxifen 4.5918625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 4.5911884234 19555203
MESH:D008175 Lung Neoplasms Zidovudine 4.5918800350
MESH:D008181 Lupus Nephritis Diethylstilbestrol 4.8715166399
MESH:D008223 Lymphoma Diethylstilbestrol 3.2815700306
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 5.2316002989
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.4819428831
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 8.9516891317 11807958 11408345 17203775
MESH:D008325 Mammary Neoplasms, Experimental Genistein 8.9514578162 12929590
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 8.9519196723 11731420 19196722 14580682 16827153
MESH:D020149 Manganese Poisoning Estradiol 11.7019453300
MESH:D020149 Manganese Poisoning Tamoxifen 11.7019453300
MESH:D008527 Medulloblastoma Tretinoin 2.6717453147
MESH:D008545 Melanoma Tamoxifen 3.1212393984 19393235
MESH:D008545 Melanoma Tretinoin 3.1216752155
MESH:D018328 Melanoma, Amelanotic Tamoxifen 3.9015990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.2919513568
MESH:D008591 Meningomyelocele Tretinoin 4.1516940565
MESH:D048629 Micronuclei, Chromosome-Defective Zidovudine 5.5517358032
MESH:D009164 Mycobacterium Infections Indinavir 5.1321442799
MESH:D009190 Myelodysplastic Syndromes Tretinoin 2.9217596541
MESH:D009203 Myocardial Infarction Genistein 2.7417141266
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.8012213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 7.8116810080
MESH:D015428 Myocardial Reperfusion Injury Genistein 7.8117141266
MESH:D009362 Neoplasm Metastasis Tamoxifen 2.4419393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.4219410462
MESH:D009369 Neoplasms Diethylstilbestrol 4.7515313581
MESH:D009369 Neoplasms Tretinoin 4.7516594593 16946489
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.7219189210 19196722 19200415
MESH:D009389 Neovascularization, Pathologic Estradiol 3.4517289903
MESH:D009421 Nervous System Malformations Diethylstilbestrol 27.9011399458
MESH:D009421 Nervous System Malformations Estradiol 27.9016427766 11399458
MESH:D009421 Nervous System Malformations Genistein 27.9016427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 27.9014600291
MESH:D009421 Nervous System Malformations Tretinoin 27.909125849
MESH:D009436 Neural Tube Defects Tretinoin 2.879142499
MESH:D019636 Neurodegenerative Diseases Acetaminophen 2.6518514411
MESH:D009503 Neutropenia Mustard Gas 3.717688884 16761898
MESH:D009765 Obesity Dietary Fats 2.2221332399 18674790 17217161 16723640 20132043 18457598 11836018 19632207 20518802
MESH:D010024 Osteoporosis Genistein 3.0819401787
MESH:D015663 Osteoporosis, Postmenopausal Genistein 3.8316169203
MESH:D010051 Ovarian Neoplasms Estradiol 10.5719401270
MESH:D010051 Ovarian Neoplasms Genistein 10.5719005980
MESH:D010051 Ovarian Neoplasms Mifepristone 10.5716525653
MESH:D010051 Ovarian Neoplasms Tretinoin 10.5716936753
MESH:D010146 Pain Acetaminophen 5.8516870215
MESH:D010146 Pain Tretinoin 5.8516870215
MESH:D010190 Pancreatic Neoplasms Tretinoin 2.3615976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.4311578682
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.9612520081
MESH:D010900 Pituitary Diseases Diethylstilbestrol 4.8914722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 4.4015687265 16977796
MESH:D011014 Pneumonia Lipopolysaccharides 4.2712224865 11605937
MESH:D011041 Poisoning Mustard Gas 3.5415727166
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.2918163543
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 14.6517184923
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 14.6511399792 11896295 11222880 11118676
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 14.6519015723 18042343 18220299
MESH:D011469 Prostatic Diseases vinclozolin 4.6518220299
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.6320887781
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 2.1417136230 15046698 15846301
MESH:D011471 Prostatic Neoplasms Estradiol 2.1416740699
MESH:D011471 Prostatic Neoplasms Genistein 2.1415378649 15256057 16925846
MESH:D011471 Prostatic Neoplasms Tamoxifen 2.1415067354
MESH:D011472 Prostatitis vinclozolin 4.6518629315
MESH:D011507 Proteinuria Tretinoin 3.3516636307
MESH:D011537 Pruritus Ethinyl Estradiol 8.5915861022 16919318
MESH:D011537 Pruritus Mustard Gas 8.5918058305
MESH:D011625 Pterygium Tretinoin 4.5116723453
MESH:D011658 Pulmonary Fibrosis Mustard Gas 2.8217620002 17266442 10334151 17894541 17720292
MESH:D012130 Respiratory Hypersensitivity Lipopolysaccharides 3.5510835634
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.5718990726
MESH:D012206 Rhabdomyolysis Lamivudine 5.269296927
MESH:D012208 Rhabdomyosarcoma Tretinoin 3.8416116481 16283617
MESH:D012852 Sinusitis Phenylephrine 4.427327846
MESH:D012871 Skin Diseases Mustard Gas 2.6412880345 16961503 15451306
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 8.668532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 8.6616192470
MESH:D012878 Skin Neoplasms Tretinoin 8.6616467112
MESH:D013088 Spermatocele Diethylstilbestrol 18.4816709447 16002989
MESH:D013088 Spermatocele Ethinyl Estradiol 18.4816709447
MESH:D013088 Spermatocele Tamoxifen 18.4816709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.7619457130
MESH:D013274 Stomach Neoplasms Tretinoin 2.6117261132
MESH:D013274 Stomach Neoplasms Zidovudine 2.6117696246
MESH:D013921 Thrombocytopenia Lipopolysaccharides 3.9215821434
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.3611994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.9215669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.6212697716
MESH:D013964 Thyroid Neoplasms Tretinoin 2.8216026305 17045167
MESH:D013978 Tibial Fractures Estradiol 4.4019048282
MESH:D014062 Tongue Neoplasms Tretinoin 3.5516051514
MESH:D014376 Tuberculosis Tretinoin 3.0616040207
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 4.8416452187 17306315 16712894
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 4.8417572228 16712894 8653321
MESH:D014581 Urticaria Acetaminophen 2.7210982225
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 8.7116175088
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 8.7116129372
MESH:D014591 Uterine Diseases Diethylstilbestrol 4.8914652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 8.5915809267 16690809
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 8.5914692618
MESH:D014604 Uveal Neoplasms Tretinoin 4.3316752155
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 10.2216002989 16513791
MESH:D014625 Vaginal Neoplasms Zidovudine 10.2212579204
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.3112125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.2914671159 15869587
MESH:D014820 Vitiligo Tretinoin 3.7916761959
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.9615886252
MESH:D015430 Weight Gain Dietary Fats 3.5016723640
MESH:D009396 Wilms Tumor Tretinoin 3.7316287080
MESH:D014947 Wounds and Injuries therapeutic 15541073
MESH:D014947 Wounds and Injuries lysophosphatidic acid 18.6815541073
MESH:D014947 Wounds and Injuries Lysophosphatidylcholines 18.6815541073
MESH:D014947 Wounds and Injuries sphingosine 1-phosphate 18.6815541073
MESH:D014947 Wounds and Injuries tetracycline CMT-8 18.6811983005 11172683
Pathway ID Pathway Name
KEGG:05146 Amoebiasis
REACT:20676 Cell junction organization
KEGG:04512 ECM-receptor interaction
KEGG:04510 Focal adhesion
KEGG:05200 Pathways in cancer
KEGG:05222 Small cell lung cancer
KEGG:05145 Toxoplasmosis
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Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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