AutismKB 2.0

Annotation Detail for LGALS3


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:LGALS3 ( CBP35,GAL3,GALBP,GALIG,L31,LGALS2,MAC2 )
Gene Full Name: lectin, galactoside-binding, soluble, 3
Band: 14q22.3
Quick LinksEntrez ID:3958; OMIM: 153619; Uniprot ID:LEG3_HUMAN; ENSEMBL ID: ENSG00000131981; HGNC ID: 6563
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
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Pathway IDPathway Name
200147Hedgehog signaling events mediated by Gli proteins
No data
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Related Diseases/Disorders Top
No data
Desease IDDesease Name
1759Skin cancer
1904Diabetes mellitus
1934Cancer
1946Thyroid gland disease
2074Asthma
No data
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C548651 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in increased expression of LGALS3 mRNAincreases expression 19933214
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene results in increased expression of LGALS3 mRNAincreases expression 20406850
C019499 2-nitrofluorene 2-nitrofluorene results in increased expression of LGALS3 mRNAincreases expression 15890375
C016583 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of LGALS3 mRNAincreases expression 15890375
D000082 Acetaminophen Acetaminophen affects the expression of LGALS3 mRNAaffects expression 17562736
D016604 Aflatoxin B1 Aflatoxin B1 results in increased expression of LGALS3 mRNAincreases expression 15890375
D000643 Ammonium Chloride Ammonium Chloride affects the expression of LGALS3 mRNAaffects expression 16483693
C006632 arsenic trioxide arsenic trioxide results in increased expression of LGALS3 mRNAincreases expression 20458559
D019324 beta-Naphthoflavone beta-Naphthoflavone results in increased expression of LGALS3 mRNAincreases expression 19737606
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of LGALS3 mRNAincreases expression 20106945
C095105 bexarotene bexarotene results in decreased expression of LGALS3 mRNAdecreases expression 16648578
D001629 Bezafibrate Bezafibrate results in increased expression of LGALS3 mRNAincreases expression 17118139
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of LGALS3 mRNAaffects expression 17484886
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of LGALS3 mRNAincreases expression 16549783
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of LGALS3 proteinincreases expression 16549783
D002251 Carbon Tetrachloride LGALS3 gene mutant form inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 mRNA]decreases reaction|increases expression 16549783
D002251 Carbon Tetrachloride LGALS3 gene mutant form inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein]decreases reaction|increases expression 16549783
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of LGALS3 mRNAaffects expression 12734012
D002251 Carbon Tetrachloride Carbon Tetrachloride promotes the reaction [PURB protein binds to LGALS3 promoter]affects binding|increases reaction 16309856
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of LGALS3 mRNAincreases expression 17522070
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of LGALS3 proteinincreases expression 12629582
16549783
D002725 Chloroform Chloroform results in increased expression of LGALS3 mRNAincreases expression 17522070
C057862 cyanoginosin LR cyanoginosin LR results in increased expression of LGALS3 mRNAincreases expression 17654400
C014347 decitabine decitabine results in increased expression of LGALS3 mRNAincreases expression 19194470
D003907 Dexamethasone Dexamethasone results in decreased expression of LGALS3 mRNAdecreases expression 17522070
D004041 Dietary Fats Dietary Fats results in decreased expression of LGALS3 mRNAdecreases expression 18042831
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of LGALS3 mRNAincreases expression 19638242
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of LGALS3 mRNAincreases expression 15289156
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of LGALS3 mRNAincreases expression 15890375
D002117 Calcitriol Calcitriol results in decreased expression of LGALS3 mRNAdecreases expression 12875902
D004128 Dimethylnitrosamine Dimethylnitrosamine results in increased expression of LGALS3 mRNAincreases expression 17547211
D004128 Dimethylnitrosamine Dimethylnitrosamine results in increased expression of LGALS3 mRNAincreases expression 15890375
D004317 Doxorubicin LGALS3 mRNA results in decreased susceptibility to Doxorubicindecreases response to substance 16322897
D004918 Erythromycin Estolate Erythromycin Estolate results in increased expression of LGALS3 mRNAincreases expression 17522070
D004958 Estradiol Estradiol affects the expression of LGALS3 mRNAaffects expression 15598610
D004958 Estradiol Estradiol results in increased expression of LGALS3 mRNAincreases expression 15289156
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of LGALS3 mRNAincreases expression 17557909
D005038 Ethylnitrosourea Ethylnitrosourea results in increased expression of LGALS3 mRNAincreases expression 15954086
D005047 Etoposide LGALS3 protein affects the susceptibility to Etoposideaffects response to substance 16217747
D005472 Fluorouracil LGALS3 protein affects the susceptibility to Fluorouracilaffects response to substance 16217747
D005480 Flurbiprofen Flurbiprofen results in increased expression of LGALS3 mRNAincreases expression 16949054
D019833 Genistein Genistein results in increased expression of LGALS3 mRNAincreases expression 15289156
D008701 Methapyrilene Methapyrilene results in increased expression of LGALS3 mRNAincreases expression 15890375
D008748 Methylcholanthrene Methylcholanthrene results in increased expression of LGALS3 mRNAincreases expression 20713471
D016685 Mitomycin LGALS3 protein affects the susceptibility to Mitomycinaffects response to substance 16217747
D009270 Naloxone Naloxone results in increased expression of LGALS3 mRNAincreases expression 17522070
D015058 1-Naphthylisothiocyanate 1-Naphthylisothiocyanate results in increased expression of LGALS3 mRNAincreases expression 17522070
C029938 nickel sulfate nickel sulfate affects the expression of LGALS3 mRNAaffects expression 12718980
C025256 nonylphenol nonylphenol results in increased expression of LGALS3 proteinincreases expression 16054331
C041786 palm oil palm oil results in decreased expression of LGALS3 mRNAdecreases expression 18042831
D010615 Phenacetin Phenacetin results in increased expression of LGALS3 mRNAincreases expression 17082564
17698508
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in increased expression of LGALS3 mRNA]affects reaction|increases expression 19482888
D010634 Phenobarbital Phenobarbital results in increased expression of LGALS3 mRNAincreases expression 19482888
C030299 phenylhydrazine phenylhydrazine results in increased expression of LGALS3 mRNAincreases expression 17082564
17698508
D010882 Piperonyl Butoxide Piperonyl Butoxide results in increased expression of LGALS3 mRNAincreases expression 15890375
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of LGALS3 mRNAaffects binding|decreases expression|increases activity 19710929
C006253 pirinixic acid pirinixic acid results in increased expression of LGALS3 mRNAincreases expression 17118139
C006253 pirinixic acid pirinixic acid results in increased expression of LGALS3 mRNAincreases expression 15890375
D011374 Progesterone LGALS3 protein affects the metabolism of Progesteroneaffects metabolic processing 17242467
C037219 quinoline quinoline analog results in increased expression of LGALS3 proteinincreases expression 18645022
D013311 Streptozocin Streptozocin results in increased expression of LGALS3 mRNAincreases expression 16684804
D013311 Streptozocin vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of LGALS3 mRNA]decreases reaction|increases expression 16684804
D013467 Sulindac Sulindac inhibits the reaction [CDKN1A protein results in increased expression of LGALS3 mRNA]decreases reaction|increases expression 15190207
D013629 Tamoxifen Tamoxifen affects the expression of LGALS3 mRNAaffects expression 14699072
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of LGALS3 mRNAincreases expression 11489354
20106945
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of LGALS3 mRNAdecreases expression 20159946
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of LGALS3 mRNAincreases expression 19933214
17337447
17035482
18796159
D013752 Tetracycline Tetracycline results in increased expression of LGALS3 mRNAincreases expression 17522070
D013806 Theophylline Theophylline results in increased expression of LGALS3 mRNAincreases expression 17522070
D013864 Thioglycolates LGALS3 protein affects the susceptibility to Thioglycolatesaffects response to substance 10702423
D014212 Tretinoin Tretinoin results in decreased expression of LGALS3 mRNAdecreases expression 12875902
D014212 Tretinoin Tretinoin results in decreased expression of LGALS3 mRNAdecreases expression 16604517
D014415 Tunicamycin Tunicamycin results in increased expression of LGALS3 mRNAincreases expression 17127020
D014635 Valproic Acid Valproic Acid results in increased expression of LGALS3 mRNAincreases expression 19101580
C034028 vanadyl sulfate vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of LGALS3 mRNA]decreases reaction|increases expression 16684804
C025643 vinclozolin vinclozolin affects the expression of LGALS3 mRNAaffects expression 19015723
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Sulindac 10.9814745880
MESH:D000008 Abdominal Neoplasms Tamoxifen 10.9814745880
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 10.756195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 10.7514514962 11752688 15322242
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 10.758875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 3.3919490988
MESH:D000138 Acidosis Ammonium Chloride 2.9618287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.3317505938
MESH:D058186 Acute Kidney Injury Sulindac 3.787897758
MESH:D055371 Acute Lung Injury nickel sulfate 7.3116100012 11954676 12718980 19131640
MESH:D055371 Acute Lung Injury pirinixic acid 7.3118653653
MESH:D000210 Acute-Phase Reaction Thioglycolates 5.759464241
MESH:D000230 Adenocarcinoma arsenic trioxide 24.8711798837 19825857
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 24.8720127859 20464547
MESH:D000230 Adenocarcinoma Dimethylnitrosamine 24.8716033868
MESH:D000230 Adenocarcinoma Doxorubicin 24.8717418594
MESH:D000230 Adenocarcinoma Estradiol 24.8711473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 24.8714692618
MESH:D000230 Adenocarcinoma Fluorouracil 24.8717638652
MESH:D000230 Adenocarcinoma Genistein 24.8711473722
MESH:D000230 Adenocarcinoma Sulindac 24.8711910360
MESH:D000236 Adenoma 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 30.6116176798
MESH:D000236 Adenoma Benzo(a)pyrene 30.616695378
MESH:D000236 Adenoma beta-Naphthoflavone 30.6119389873
MESH:D000236 Adenoma Diethylnitrosamine 30.616695378 10737359
MESH:D000236 Adenoma Dimethylnitrosamine 30.6119555203
MESH:D000236 Adenoma Ethylnitrosourea 30.616695378
MESH:D000236 Adenoma Methylcholanthrene 30.616695378 10545420
MESH:D000236 Adenoma Sulindac 30.6110223192
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 19.9519061943 16434500 17620307 17162532 18056438 19052882
MESH:D018248 Adenoma, Liver Cell Phenobarbital 19.9517620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 19.9516434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 19.9516835633
MESH:D011125 Adenomatous Polyposis Coli Flurbiprofen 8.5710680582
MESH:D011125 Adenomatous Polyposis Coli Sulindac 8.5711535846 12394442 11874996 17611924 15623613 16460482 19003578
MESH:D000419 Albuminuria Doxorubicin 3.9721441931
MESH:D000505 Alopecia Tretinoin 3.1315955085
MESH:D000550 Amblyopia Valproic Acid 4.6217688650
MESH:D000686 Amyloidosis Diethylstilbestrol 3.9115469931
MESH:D000740 Anemia Fluorouracil 16.9915504547 17963324 16511603
MESH:D000740 Anemia Phenacetin 16.992444515
MESH:D000740 Anemia phenylhydrazine 16.992444515
MESH:D000740 Anemia Tetrachlorodibenzodioxin 16.9911748828
MESH:D000743 Anemia, Hemolytic Phenacetin 9.261949026 17698508 17082564
MESH:D000743 Anemia, Hemolytic phenylhydrazine 9.2617698508 17084956 17082564
MESH:D000799 Angioedema Acetaminophen 3.2310982225
MESH:D001008 Anxiety Disorders Valproic Acid 7.2517497229
MESH:D001008 Anxiety Disorders vinclozolin 7.2519015723
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.4919183758
MESH:D001161 Arteriosclerosis Dietary Fats 7.9715238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 7.9711256880
MESH:D001169 Arthritis, Experimental Dexamethasone 9.9817659584
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 9.9815885639
MESH:D001169 Arthritis, Experimental Tretinoin 9.9816412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.1016292516
MESH:D001249 Asthma Theophylline 4.6512113382 9701106
MESH:D001249 Asthma Tretinoin 4.6516456186
MESH:D050197 Atherosclerosis Methylcholanthrene 3.0811922910
MESH:D001321 Autistic Disorder Acetaminophen 1.8718445737
MESH:D001321 Autistic Disorder Valproic Acid 1.8720603192 18775368 19460635 18940202 15238991 17688650 18558336 17157402 18985861 19232924 17507914 16609825 18177632 18316065 18396377
MESH:D001471 Barrett Esophagus Tretinoin 3.8316935849
MESH:D001714 Bipolar Disorder Valproic Acid 2.7420046352 17594078
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 17.5316206674
MESH:D001778 Blood Coagulation Disorders pirinixic acid 17.5319483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 17.5312125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 17.5316206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.1815340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 6.6615746008
MESH:D001848 Bone Diseases, Developmental Valproic Acid 6.668888407
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 10.1214601052
MESH:D019046 Bone Marrow Neoplasms Etoposide 10.1214601052
MESH:D001913 Bowen's Disease Sulindac 4.7411207687
MESH:D001927 Brain Diseases Ethylnitrosourea 4.3514991843
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 4.7217868700
MESH:D001930 Brain Injuries Progesterone 3.6715665606 15380490 15845082
MESH:D001932 Brain Neoplasms Doxorubicin 7.3617150277
MESH:D001932 Brain Neoplasms Ethylnitrosourea 7.3618412241 16357521 16436596 16651633 15144691
MESH:D001943 Breast Neoplasms 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 19.4020146248
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 19.4020146248 17474063
MESH:D001943 Breast Neoplasms bexarotene 19.4016344269 16818667
MESH:D001943 Breast Neoplasms Calcitriol 19.4011237771
MESH:D001943 Breast Neoplasms decitabine 19.4019208741 18320071
MESH:D001943 Breast Neoplasms Dietary Fats 19.4020435547
MESH:D001943 Breast Neoplasms Diethylnitrosamine 19.4017474063
MESH:D001943 Breast Neoplasms Diethylstilbestrol 19.4017129689 15324884
MESH:D001943 Breast Neoplasms Doxorubicin 19.4015994142 16115903 16264153 15567936 18695136 17426702 15136595 11325840 16096432 18382427 15939500 15668708 15692762 16935488 18628466 19526202 15993339 17983394 16595493 18234424 16826403 16322301 15634643 17369602
MESH:D001943 Breast Neoplasms Estradiol 19.4016675129 14630087 12948864 17018787 17289903 17261762 19861407 18497071
MESH:D001943 Breast Neoplasms Etoposide 19.4016322251
MESH:D001943 Breast Neoplasms Fluorouracil 19.4015136595 16595493 19217205 18357371 16557594 16110121 18608205
MESH:D001943 Breast Neoplasms Genistein 19.4016541309 16873071 17200150
MESH:D001943 Breast Neoplasms Methylcholanthrene 19.4017474063
MESH:D001943 Breast Neoplasms Progesterone 19.4016175315 15562024 17614352
MESH:D001943 Breast Neoplasms Sulindac 19.4016642371
MESH:D001943 Breast Neoplasms Tamoxifen 19.4021138602 19084267 16818667 20135344 19289846 15565566 19066611 15668708 19244106 20544844 19103187 11161223 20390343 19011961 20005174 18815881 16273361 19221464 16873071 17893378 20065188 19115204 19059307 18855134 17261762 19189212 17440819 19155303 17242785 18351453 19200415 19189210 20859285 16202921 18821012 19142967 19410462 18629630 18425577 19288272 17049068 19487384 21152245 18984771 18997820
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 19.4020435547
MESH:D001943 Breast Neoplasms Tretinoin 19.4016166294 16443354 16873071
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 3.9916813970
MESH:D002051 Burkitt Lymphoma arsenic trioxide 3.7711589617
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 3.8616111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.2016011737 15673190 16124888 16227642 16192424 15700767 16097048 15721981 10355542 3786805 16050911 18705752
MESH:D002276 Carcinoid Tumor Doxorubicin 17.6916051944
MESH:D002276 Carcinoid Tumor Fluorouracil 17.6916051944
MESH:D002276 Carcinoid Tumor Streptozocin 17.6916051944
MESH:D002277 Carcinoma Dimethylnitrosamine 16.0119555203
MESH:D002277 Carcinoma Fluorouracil 16.0117121937
MESH:D002277 Carcinoma Methylcholanthrene 16.0110545420
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 16.0116835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 3.9219066611
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.5516168501
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 35.3516705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 35.353084413
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 35.3521507988 12619106 12907637
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 35.3511135700 16217749 15553829 14691202 15073043
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 35.3518788625
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 35.3519418558 20514400 20512989 20214788 20101231 18788625 18665156 3084413 16698587 16878318 18494052 16328049 21159647 18393292 16830150 20727157 20935162 17173139 19107877 16288022 16681979 17055752 17428255 16569478 18971187 19208518 18691550 16502159 16540662 20524982 10737359 19171122 19822196 19919837 3581430 17138121 19335982 19052882 19383236 17761372 17162532 17978847 20432363 18506893 18978308 19701751 16779866 16935385 18056438 19539802 20007298 10672840 18785209 18210153 19394651 20084675 19519916 11831363 16807293
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 35.3515948411 16924424
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 35.3516234567 18059187 17876044 16023760
MESH:D006528 Carcinoma, Hepatocellular Estradiol 35.3516924424
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 35.3517088986 17045692 17971768 16332177 16799960 18930000
MESH:D006528 Carcinoma, Hepatocellular Genistein 35.3516924424
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 35.3517173139 20007298 20935162 6705139 1701930
MESH:D006528 Carcinoma, Hepatocellular quinoline 35.35598648
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 35.3516924424
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 35.351917145
MESH:D002289 Carcinoma, Non-Small-Cell Lung bexarotene 2.9916247446
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.2619014326
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 5.611485588 16201981
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 5.6118695887
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.5912490120
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 18.6220419170
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 18.6211237771
MESH:D002294 Carcinoma, Squamous Cell decitabine 18.6219215824
MESH:D002294 Carcinoma, Squamous Cell Dimethylnitrosamine 18.6216033868
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 18.626189445
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 18.6216757204 16280240 18986760 17066447
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 18.6216051514 16096774
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.0917572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.0118850075 18670907 16120746
MESH:D009202 Cardiomyopathies Doxorubicin 3.1216455267 16269455 15811867 18627295 16278810 16651473 16612575 16364871 17974986 16731534 17924179 17519947 17382496 16109756 17007740 17351982 16242529 15505089 17928571 17131338 16952015 15476868 15792986 17329180 17308081
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.7116243910 17334414
MESH:D002318 Cardiovascular Diseases Genistein 2.8816332659
MESH:D002386 Cataract Acetaminophen 5.9610977129
MESH:D002386 Cataract Tretinoin 5.9617460283
MESH:D002471 Cell Transformation, Neoplastic marker/mechanism 16322222
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 16.556135515
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 16.552727394 17174075 7505956 21159647
MESH:D002471 Cell Transformation, Neoplastic Estradiol 16.5518566989
MESH:D002471 Cell Transformation, Neoplastic Ethylnitrosourea 16.5516003739
MESH:D002471 Cell Transformation, Neoplastic Methylcholanthrene 16.5516192471
MESH:D002493 Central Nervous System Diseases Phenobarbital 3.674080065
MESH:D016543 Central Nervous System Neoplasms Ethylnitrosourea 5.3717160924
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 3.9916129372
MESH:D002637 Chest Pain Theophylline 5.2615238202
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.4620734317
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 7.6219052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 7.6216835633
MESH:D002761 Cholangitis 1-Naphthylisothiocyanate 5.5912912871
MESH:D002779 Cholestasis 1-Naphthylisothiocyanate 10.887624871 15913567 12927374 15500046 18590720 19486331 16629650 18164287
MESH:D002779 Cholestasis Ethinyl Estradiol 10.8815861022 16105132 17333356 17681005 17110522 16919318 11677210
MESH:D002779 Cholestasis pirinixic acid 10.8819176532
MESH:D002780 Cholestasis, Intrahepatic 1-Naphthylisothiocyanate 5.2419407337 10220858
MESH:D002822 Choriocarcinoma Tretinoin 4.5516461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 4.8015340226 8697196 12621046 15668235 16354765
MESH:D002972 Cleft Palate Tretinoin 4.809407595
MESH:D003092 Colitis Tretinoin 3.1217035595
MESH:D003110 Colonic Neoplasms decitabine 9.4517616700
MESH:D003110 Colonic Neoplasms Dexamethasone 9.4515824018
MESH:D003110 Colonic Neoplasms Fluorouracil 9.4516510598 17016597 15001691 17172411 17725105 16340194 17287894 18772588 17169374 17018589
MESH:D003110 Colonic Neoplasms Genistein 9.4517182828
MESH:D003110 Colonic Neoplasms Sulindac 9.4512458338 12902858
MESH:D015179 Colorectal Neoplasms arsenic trioxide 5.6120501625
MESH:D015179 Colorectal Neoplasms decitabine 5.6118981723
MESH:D015179 Colorectal Neoplasms Doxorubicin 5.6118802399 18259882
MESH:D015179 Colorectal Neoplasms Fluorouracil 5.6116524972 17016601 16303861 17594712 20501625 14970324 17094418 16391804 17695437 18448328 18509181 15289873 18802399 17255274 18383874 18949393 16331619 18288408 17401013 17454858 15148649 16282729
MESH:D015179 Colorectal Neoplasms Sulindac 5.6111076880 18059344 10666051 11197048
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.5514669216 17141729
MESH:D023903 Coronary Restenosis arsenic trioxide 3.6112609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 6.3210525206
MESH:D019465 Craniofacial Abnormalities Dexamethasone 6.3217728286
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 6.3210048152 15322242 20055451
MESH:D019465 Craniofacial Abnormalities Tretinoin 6.328800419 10589399 9224671 17551590 9125849 16925845 9664655 9211117 14991402 9142499
MESH:D019465 Craniofacial Abnormalities Valproic Acid 6.3216575769 8888407 17688650
MESH:D003456 Cryptorchidism Diethylstilbestrol 9.4716002989 12952375
MESH:D003456 Cryptorchidism vinclozolin 9.4714966744
MESH:D003490 Cyanosis 2,6-dinitrotoluene 3.4318551238
MESH:D007644 Darier Disease Fluorouracil 4.1916733453
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.5415213294
MESH:D003711 Demyelinating Diseases Tamoxifen 3.7719031437
MESH:D017449 Dermatitis, Allergic Contact Dexamethasone 5.4812438553
MESH:D017449 Dermatitis, Allergic Contact nickel sulfate 5.4816780908 16823706 11298694
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.1218249437
MESH:D003920 Diabetes Mellitus Streptozocin 4.2216285004
MESH:D003921 Diabetes Mellitus, Experimental Streptozocin 7.4111055810 16684804 18715473 7637645 19586609 15862027 8740154 18603373 15831366 2177838 12093613 12446591 17874149 16286809 1374869 19496084 12644472 19960420 6379147 15298345 12083368 11260395 19298542 17442507
MESH:D003921 Diabetes Mellitus, Experimental vanadyl sulfate 7.4116684804
MESH:D003922 Diabetes Mellitus, Type 1 Streptozocin 3.4218603373
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 8.6920387270
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 8.6916647724
MESH:D003924 Diabetes Mellitus, Type 2 Streptozocin 8.6919647726 19586609
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 8.6917107852
MESH:D058065 Diabetic Cardiomyopathies Streptozocin 5.1216025228
MESH:D003928 Diabetic Nephropathies Estradiol 12.1719279558
MESH:D003928 Diabetic Nephropathies Streptozocin 12.1719682444 19960420
MESH:D003928 Diabetic Nephropathies Tamoxifen 12.1719279558
MESH:D003929 Diabetic Neuropathies Progesterone 3.9117187935
MESH:D003930 Diabetic Retinopathy Streptozocin 10.3617662242
MESH:D003930 Diabetic Retinopathy Sulindac 10.3612861449 17621415
MESH:D003967 Diarrhea Dexamethasone 3.147237001
MESH:D056486 Drug-Induced Liver Injury 1-Naphthylisothiocyanate 35.2818289764 7624871 17522070 20133375
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 35.2821346803 18551238
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 35.2819923254 11287661 15619225 15968718 11743745 19085960 11421492 11461765 12392966 12705907 19370779 16177239 14550746 17906064 19420014 16109766 16485898 16227642 18713872 14725611 16393943 16781746 10663392 19416960 11739529 11834606 12594235 12958197 17522070 18071297 10774834 16081117 17562736 10915739 12153990 14986274 12540782 19739265 11529661 2444490 19164858
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 35.2817522070 7120509 19336974 3786805 19085960 11566570 4309450 6623471 10915739 15027814 16177239 15998439 9327722 6884620 7440962 7179309 15968718 3732212 16227642 10092053 2869522 21278145
MESH:D056486 Drug-Induced Liver Injury Chloroform 35.287440962 7120509 17522070 3732212 6623471 2862719 6884620 3104120
MESH:D056486 Drug-Induced Liver Injury cyanoginosin LR 35.2817654400
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 35.2819107877
MESH:D056486 Drug-Induced Liver Injury Dimethylnitrosamine 35.288172417
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 35.2817416283
MESH:D056486 Drug-Induced Liver Injury Erythromycin Estolate 35.2814998559 17522070
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 35.2820420201
MESH:D056486 Drug-Induced Liver Injury Tetracycline 35.2817522070
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 35.2819641884 1733752
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.4919426721
MESH:D004362 Drug Toxicity Doxorubicin 6.5918602426
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 6.5911462148
MESH:D050171 Dyslipidemias Dietary Fats 3.0118367378
MESH:D004421 Dystonia Phenobarbital 8.591851702
MESH:D004421 Dystonia Valproic Acid 8.591851702
MESH:D004476 Ectodermal Dysplasia Ethylnitrosourea 5.3718357618
MESH:D004485 Eczema Dexamethasone 3.8912438553
MESH:D004487 Edema Dexamethasone 8.3719703484
MESH:D004487 Edema pirinixic acid 8.3712083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 8.3711000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 9.9118230668 15322242 16714409
MESH:D004489 Edema, Cardiac Tretinoin 9.9118230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 17.2615138306
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 17.2612538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 17.2617692515
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 17.2619031437
MESH:D004701 Endocrine Gland Neoplasms decitabine 4.5019294695
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 9.9016402032
MESH:D004714 Endometrial Hyperplasia Genistein 9.9016402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 23.7516804899 15700306
MESH:D016889 Endometrial Neoplasms Doxorubicin 23.7517359293
MESH:D016889 Endometrial Neoplasms Estradiol 23.7511473722 18566989 19148513
MESH:D016889 Endometrial Neoplasms Genistein 23.7511473722
MESH:D016889 Endometrial Neoplasms Tamoxifen 23.7520544844 16202921 17893378 19155303
MESH:D016889 Endometrial Neoplasms Tretinoin 23.7516569247
MESH:D004715 Endometriosis Progesterone 12.3116134523
MESH:D004715 Endometriosis Sulindac 12.3115652904
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 12.319294722 10568697
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 4.5418037988
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 8.853659116
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 8.8517275665 3659116
MESH:D004828 Epilepsies, Partial Phenobarbital 7.953922381 11558140
MESH:D004828 Epilepsies, Partial Valproic Acid 7.953922381 16628512
MESH:D004827 Epilepsy Phenobarbital 5.5220417680
MESH:D004827 Epilepsy Valproic Acid 5.5220417680 18234410
MESH:D004832 Epilepsy, Absence Naloxone 12.146254150
MESH:D004832 Epilepsy, Absence Phenobarbital 12.146401628
MESH:D004832 Epilepsy, Absence Valproic Acid 12.146426943 6254150 7562514
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 9.357750514
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 9.357750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 8.493659116
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 8.493659116
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.5016302075
MESH:D004938 Esophageal Neoplasms marker/mechanism 17634542
MESH:D004938 Esophageal Neoplasms arsenic trioxide 11.7112903497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 11.7116530937
MESH:D004938 Esophageal Neoplasms Dimethylnitrosamine 11.7117016578
MESH:D004938 Esophageal Neoplasms Fluorouracil 11.7115173087 16481741 16337965 17638652 16785472
MESH:D004938 Esophageal Neoplasms Sulindac 11.7112235107
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 7.3011564622
MESH:D005124 Eye Abnormalities Tretinoin 7.309664655 16938888
MESH:D005234 Fatty Liver arsenic trioxide 39.2215073043
MESH:D005234 Fatty Liver Carbon Tetrachloride 39.2212631006 16045604 15959796 19224547 17595544 12795759 61145 16239168
MESH:D005234 Fatty Liver Dietary Fats 39.2219004024 17967931 18296743 19551842
MESH:D005234 Fatty Liver Diethylnitrosamine 39.2220387270 21071580
MESH:D005234 Fatty Liver Ethinyl Estradiol 39.2215345470
MESH:D005234 Fatty Liver pirinixic acid 39.2220131406 19236843
MESH:D005234 Fatty Liver Tamoxifen 39.2219224547 14986274
MESH:D005234 Fatty Liver Tetracycline 39.2219224547 16917069
MESH:D005234 Fatty Liver Valproic Acid 39.2214986274 19224547
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 6.9115751030 16611131 16534752 16513791 16002989
MESH:D052776 Female Urogenital Diseases Tamoxifen 6.9116709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 2.8711858732
MESH:D005315 Fetal Diseases Valproic Acid 4.2716575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 3.568888407 18558336
MESH:D018221 Fibromatosis, Abdominal Sulindac 10.9614745880
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 10.9614745880
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 16.0819069698
MESH:D018222 Fibromatosis, Aggressive Sulindac 16.0819069698
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 16.0819069698
MESH:D005354 Fibrosarcoma Methylcholanthrene 4.3414633661 10962813
MESH:D005355 Fibrosis Carbon Tetrachloride 16.3718705752
MESH:D005355 Fibrosis Dietary Fats 16.3718296743
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 16.3720067830
MESH:D005355 Fibrosis Tretinoin 16.3717994277
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.6916904648
MESH:D005756 Gastritis Acetaminophen 3.0616983495
MESH:D005764 Gastroesophageal Reflux Sulindac 4.4411910360
MESH:D030342 Genetic Diseases, Inborn vinclozolin 4.3316973722
MESH:D005832 Genital Diseases, Male vinclozolin 4.6916417039
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 4.3516452187
MESH:D005909 Glioblastoma Doxorubicin 13.6017150277
MESH:D005909 Glioblastoma Ethylnitrosourea 13.6016436596
MESH:D005909 Glioblastoma Genistein 13.6016598420
MESH:D005909 Glioblastoma Tretinoin 13.6017312396
MESH:D005910 Glioma Ethylnitrosourea 5.4216651633 16357521 18412241
MESH:D005910 Glioma Fluorouracil 5.4216145905
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 3.9810696789
MESH:D006258 Head and Neck Neoplasms decitabine 14.9719215824
MESH:D006258 Head and Neck Neoplasms Doxorubicin 14.9715692506
MESH:D006258 Head and Neck Neoplasms Fluorouracil 14.9715162350 15102660 18337622
MESH:D006258 Head and Neck Neoplasms Tretinoin 14.9716096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.5516084493
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 9.0620471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 9.0610048152 11294989
MESH:D006330 Heart Defects, Congenital Tretinoin 9.0614991402 9664655
MESH:D006331 Heart Diseases Doxorubicin 6.6716244372 16244371 18006777 16144979 14766674 16330681 16495754 17888722 17875725 12587719 16879835 18674790 16707910
MESH:D006331 Heart Diseases Streptozocin 6.6712093613
MESH:D006333 Heart Failure Doxorubicin 5.7317481944
MESH:D006333 Heart Failure pirinixic acid 5.7320558911
MESH:D006390 Hemangioendothelioma quinoline 5.29598648
MESH:D006394 Hemangiosarcoma Doxorubicin 7.8415692506
MESH:D006394 Hemangiosarcoma quinoline 7.84598648
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.8011000095
MESH:D006505 Hepatitis 1-Naphthylisothiocyanate 7.7718590720
MESH:D006505 Hepatitis Carbon Tetrachloride 7.7719900420 19110552
MESH:D006529 Hepatomegaly Phenobarbital 11.0116109766
MESH:D006529 Hepatomegaly pirinixic acid 11.0119772884 16221962 18467677 19176532
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 11.0115340226 16120746 12621046
MESH:D006548 Hernia, Diaphragmatic Dexamethasone 2.837520565
MESH:D006558 Herpes Genitalis Estradiol 4.4215709030
MESH:D006561 Herpes Simplex Etoposide 3.9710809021
MESH:D006689 Hodgkin Disease Doxorubicin 6.0717606976 15147373 18501091
MESH:D006689 Hodgkin Disease Etoposide 6.0718180244 16135485 17606976 16200630 15147373
MESH:D019584 Hot Flashes Estradiol 3.1417088409
MESH:D006849 Hydrocephalus Valproic Acid 4.2717688650
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.4315340226 16959395 8697196 16354765 18606429
MESH:D006930 Hyperalgesia Acetaminophen 6.0316870215
MESH:D006930 Hyperalgesia Tretinoin 6.0316870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 3.9316899240
MESH:D006937 Hypercholesterolemia Dietary Fats 3.0621332399
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 3.9816778211
MESH:D006943 Hyperglycemia pirinixic acid 2.6620558911
MESH:D006949 Hyperlipidemias Dietary Fats 3.0721332399
MESH:D006965 Hyperplasia Diethylstilbestrol 3.8512960047 14722030
MESH:D006973 Hypertension Dexamethasone 4.3617042910
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 4.3618850075 18670907
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.5015338365
MESH:D007021 Hypospadias Diethylstilbestrol 9.2916002989
MESH:D007021 Hypospadias Ethinyl Estradiol 9.2916945680 16569931
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 3.8215869954
MESH:D007246 Infertility Diethylstilbestrol 3.7815036965
MESH:D007247 Infertility, Female Ethinyl Estradiol 2.9112013081
MESH:D007248 Infertility, Male decitabine 12.6617581917
MESH:D007248 Infertility, Male Ethinyl Estradiol 12.6617937319
MESH:D007248 Infertility, Male Theophylline 12.6616988215
MESH:D007248 Infertility, Male vinclozolin 12.6616467254
MESH:D007249 Inflammation Dexamethasone 22.548960868 11099482
MESH:D007249 Inflammation Dietary Fats 22.5420412841
MESH:D007249 Inflammation Diethylnitrosamine 22.5418785209
MESH:D007249 Inflammation Flurbiprofen 22.5411099482
MESH:D007249 Inflammation Progesterone 22.5415869954
MESH:D007249 Inflammation Sulindac 22.543291741
MESH:D007249 Inflammation Tamoxifen 22.5419457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 22.5412200463 12878042
MESH:D007333 Insulin Resistance Dietary Fats 9.8911836018 18457598
MESH:D007333 Insulin Resistance Estradiol 9.8916393666 16627594
MESH:D007333 Insulin Resistance pirinixic acid 9.8916306350
MESH:D007410 Intestinal Diseases Tretinoin 3.1817994277
MESH:D007414 Intestinal Neoplasms Sulindac 4.1110213222 12584176 12628509 12663524 12351151 10223192
MESH:D007417 Intestinal Polyps Sulindac 4.4311245490 12394442
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 8.1416580747
MESH:D007569 Jaw Abnormalities Tretinoin 8.1417551590 15992940
MESH:D007674 Kidney Diseases Acetaminophen 11.4215629191 12587719
MESH:D007674 Kidney Diseases Doxorubicin 11.4215699352 15369732 16775033
MESH:D007674 Kidney Diseases Estradiol 11.4215618244
MESH:D007674 Kidney Diseases Streptozocin 11.4212093613
MESH:D007676 Kidney Failure, Chronic Doxorubicin 3.6116707910
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 22.7316705839
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 22.7316762066 15003126 14681315
MESH:D007680 Kidney Neoplasms Estradiol 22.7315610895
MESH:D007680 Kidney Neoplasms Ethylnitrosourea 22.7317379185
MESH:D007680 Kidney Neoplasms Fluorouracil 22.7316985049
MESH:D007680 Kidney Neoplasms Tamoxifen 22.7318625569
MESH:D007859 Learning Disorders Diethylstilbestrol 3.4817184923
MESH:D007938 Leukemia arsenic trioxide 12.2115070760
MESH:D007938 Leukemia decitabine 12.2119235587 18980019
MESH:D007938 Leukemia Genistein 12.2118980019 17468513
MESH:D007938 Leukemia Tretinoin 12.2117143497
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 4.5416085563
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.2617077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 3.7116972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 2.9714633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 12.8819077051
MESH:D007951 Leukemia, Myeloid decitabine 12.8817236224 19117987 18454857
MESH:D007951 Leukemia, Myeloid Tretinoin 12.8816932348 16482212 19285840
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 7.5017050201 16968895 16467208 20471514 19850784
MESH:D015470 Leukemia, Myeloid, Acute decitabine 7.5017679729 18206229 19010910 19387464 18460780 18704418
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 7.5017596541 16294345 19850784
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 7.5017596541 16294345
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 4.8518055864
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 6.2516112521 16331271 12679006 19642359 16823087 16330433 11468182 12018890 19035177 19225113 19075265 15748426 17649720 17107899 9834237 17217047 15213294 15622746 16891316 16966277 12712474 17869043 17712046 11161223 15336539
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 6.2517107899 17506722 17339181 17217047 9834237 16935935 16891316 15748426 17361223 12679006 16823087 19225113 19035177 17712046 19642359 16331271 17294898 16766008 17649720 17301526 16788101 16140955 19075265 17368321 19029980
MESH:D015458 Leukemia, T-Cell arsenic trioxide 3.7816882451
MESH:D007984 Leydig Cell Tumor vinclozolin 4.1316417039
MESH:D017880 Limb Deformities, Congenital Tretinoin 2.869224671
MESH:D008064 Lipidoses Tamoxifen 2.7117567588 15342952
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 12.7716943688 17334410 11408273 16239168 21278145 17174718 11903743 16221502 17157831
MESH:D008103 Liver Cirrhosis Dietary Fats 12.7718296743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 12.7720032147 18665156 18522880 18407596 19638242
MESH:D008103 Liver Cirrhosis Phenobarbital 12.7721047994
MESH:D008105 Liver Cirrhosis, Biliary Sulindac 3.8212468960
MESH:D008106 Liver Cirrhosis, Experimental marker/mechanism 16549783
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 15.8816116963 12632512 17976157 16192424 17565644 17631135 15959796 17721639 18317297 12632514 16011737 12667390 18263696 18205269 15925388 15893842 12649538 12958196 18412020 15996030 18395914 15650968 14512876 18429990 16136751 11481614 15338365 18156304 18054572 17900296 15370692 12741479 15730626 18418968 14620537 12586293 16248980 20821823 18210741 18279442 18472332 18420326 12546737 17640975 14716496 18166357 18006644 17525996 17761835 18481824 16015684 12609069 17714472 13678700 17698563 18395095 12666154 16027843 17708605 15876570 17922224 18339082 15931870 18187930 17823541 15362042 18277467 12898905 17869086 15123356 14748882 16033810 17805973 12445421 15052691 17944888 12389079 17766677 17557913 18705752 16638106 15057751 18251166 10355542 18472094 14724832 18376398 14716833 15818738 16097048 12445418 17481882 15673190
MESH:D008106 Liver Cirrhosis, Experimental Dexamethasone 15.8816718785
MESH:D008106 Liver Cirrhosis, Experimental Dimethylnitrosamine 15.8815492853 15504291 18210741 15571005 18371158 18629640 17348192 16169303 15733078 17432682 17465448 15577212 17719030 14568256 15864749 16627068 12918455 17724770 15763062 17198567 15798949 18239293 17534399 16009107 17196135 16570917 15138612 17203207 18237412 15383259 14709902 17201889 16042886 15161499 18095165 14726149 15479170 15591649 17666798 16603200 12925901 14643895 18672772 15723089 15086199 15369754 14659978 15744066 18364076 15793283 15081153 18637143 15099470 18567088 15842777 16544323 15298665 15942678 17881167 15067225 17036385 16270385 15339415 17640959 15366600
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 15.8816595196 16439617
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 15.8814659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental Genistein 15.8817823541
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 15.8815474484
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 15.8818564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 15.8812878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 15.8818397230 16248980
MESH:D008107 Liver Diseases 1-Naphthylisothiocyanate 13.2517184895
MESH:D008107 Liver Diseases Acetaminophen 13.2512587719 19784758 16611625 12969438 16610002 19014921 11587558 19460945
MESH:D008107 Liver Diseases Carbon Tetrachloride 13.2516964402 17285989 15720792 16246199 15830285
MESH:D008107 Liver Diseases Diethylnitrosamine 13.2517034775
MESH:D008107 Liver Diseases Phenobarbital 13.2519363144
MESH:D008107 Liver Diseases Sulindac 13.2514986274 16867024
MESH:D017093 Liver Failure Carbon Tetrachloride 3.5815123358
MESH:D017114 Liver Failure, Acute Acetaminophen 13.2316871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 13.2314706259 16899240
MESH:D017114 Liver Failure, Acute Dimethylnitrosamine 13.2317457977
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 66.197678174
MESH:D008113 Liver Neoplasms 2-nitrofluorene 66.1915890375
MESH:D008113 Liver Neoplasms 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 66.1915890375
MESH:D008113 Liver Neoplasms Aflatoxin B1 66.192125692 15890375 9163691 18177683
MESH:D008113 Liver Neoplasms arsenic trioxide 66.1914682389
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 66.1920195826 21137059
MESH:D008113 Liver Neoplasms beta-Naphthoflavone 66.1919389873 21295105
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 66.1919294768
MESH:D008113 Liver Neoplasms Diethylnitrosamine 66.1920501860 19294768 16942905 20452335 18978307 18644402 19090486 20137499 20583210 20101389 19850985 12771043 19551842 19426721 15885732 19638242 19996281 18977376 20118626 18648771 19256749 19499222 9163691 15175105 21047994 19254457 19833225 12112319 19642983 21278145 20434301 18754104 19255062 19690152 19427195 19812893 21167192 10737359 21071580 20405173 2862719 20492335 19073162 2422723
MESH:D008113 Liver Neoplasms Diethylstilbestrol 66.1915890375 16712894
MESH:D008113 Liver Neoplasms Dimethylnitrosamine 66.193113478 15890375
MESH:D008113 Liver Neoplasms Fluorouracil 66.1916603448 17045692 18383874 15113037
MESH:D008113 Liver Neoplasms Methapyrilene 66.1915890375
MESH:D008113 Liver Neoplasms Mitomycin 66.1915113037
MESH:D008113 Liver Neoplasms Phenobarbital 66.1919812893 19073162 19482888 15975961 8742319 21047994
MESH:D008113 Liver Neoplasms Piperonyl Butoxide 66.1919690152 20101389 15890375 18648771
MESH:D008113 Liver Neoplasms pirinixic acid 66.1916377806 20007298 15890375
MESH:D008113 Liver Neoplasms Tamoxifen 66.1916684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 66.1916984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 39.452876784 6135515 2876786
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 39.458603461
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 39.4520377131
MESH:D008114 Liver Neoplasms, Experimental beta-Naphthoflavone 39.4518164116
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 39.4512014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 39.4517174075 18775883 18282651 18164116 21159647 18544905 3124819 19539802 19126423 19009564 18308698 18079962 19519916 18253720 17854601 16267830 2563599 17942915 19004024 16842330 18093689 9362446
MESH:D008114 Liver Neoplasms, Experimental Dimethylnitrosamine 39.4515603536 6150874 1848544
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 39.4517085340 16842330
MESH:D008114 Liver Neoplasms, Experimental Methylcholanthrene 39.451399818 598648
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 39.4518308698 1399818 2563599 17172636 6150874
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 39.4512151625
MESH:D008133 Long QT Syndrome arsenic trioxide 2.8915213294
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 3.6517228818
MESH:D008175 Lung Neoplasms 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 28.4415893417 15172992 14755239 12438228 18508827 17139156 19931552 16401635 18813816 9255578 16061637
MESH:D008175 Lung Neoplasms Aflatoxin B1 28.4414755239
MESH:D008175 Lung Neoplasms arsenic trioxide 28.4419825857 11798837
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 28.4417053015 18816296 18520028 18569708 20064080 6695378 20869020 20464547 20135361
MESH:D008175 Lung Neoplasms bexarotene 28.4417849452
MESH:D008175 Lung Neoplasms Dexamethasone 28.4415824018 11195469
MESH:D008175 Lung Neoplasms Diethylnitrosamine 28.4421163286 20970405 20512841 6695378
MESH:D008175 Lung Neoplasms Dimethylnitrosamine 28.4416061637 19555203 11884234
MESH:D008175 Lung Neoplasms Doxorubicin 28.4417418594 6189445
MESH:D008175 Lung Neoplasms Ethylnitrosourea 28.4417703301 16019985 16271038 6695378
MESH:D008175 Lung Neoplasms Fluorouracil 28.4415246190
MESH:D008175 Lung Neoplasms Methylcholanthrene 28.4411893704 20970405 17909032 16337739 6695378 16271038 10545420 1399818 21163286 7750092 20512841 15390079 9230183
MESH:D008175 Lung Neoplasms Sulindac 28.4419359593 15713900
MESH:D008175 Lung Neoplasms Tamoxifen 28.4418625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 28.4419555203 11884234
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.1915086387
MESH:D008181 Lupus Nephritis Diethylstilbestrol 4.5515166399
MESH:D008223 Lymphoma decitabine 18.7719470736
MESH:D008223 Lymphoma Diethylstilbestrol 18.7715700306
MESH:D008223 Lymphoma Doxorubicin 18.7716098063
MESH:D008223 Lymphoma Ethylnitrosourea 18.7715790496
MESH:D008223 Lymphoma Etoposide 18.7712556972 12854902
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 3.3017654614
MESH:D016399 Lymphoma, T-Cell Doxorubicin 9.7515621674
MESH:D016399 Lymphoma, T-Cell Ethylnitrosourea 9.7515375218
MESH:D016410 Lymphoma, T-Cell, Cutaneous bexarotene 4.5611161223
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 4.9016002989
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.1619428831
MESH:D008325 Mammary Neoplasms, Experimental bexarotene 22.2619196722 19196723 15591091
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 22.2615458769
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 22.2611807958 17203775 16891317 11408345
MESH:D008325 Mammary Neoplasms, Experimental Ethylnitrosourea 22.2610767621 18041768 10838139
MESH:D008325 Mammary Neoplasms, Experimental Genistein 22.2614578162 12929590
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 22.2617203775 11408345
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 22.2619196722 14580682 19196723 11731420 16827153
MESH:D020149 Manganese Poisoning Estradiol 10.6119453300
MESH:D020149 Manganese Poisoning Tamoxifen 10.6119453300
MESH:D008527 Medulloblastoma Tretinoin 2.5117453147
MESH:D008545 Melanoma decitabine 8.2516505122 17785578
MESH:D008545 Melanoma Doxorubicin 8.2516827129
MESH:D008545 Melanoma Sulindac 8.2516642371
MESH:D008545 Melanoma Tamoxifen 8.2519393235 12393984
MESH:D008545 Melanoma Tretinoin 8.2516752155
MESH:D018328 Melanoma, Amelanotic Tamoxifen 3.5815990972
MESH:D008546 Melanoma, Experimental Acetaminophen 2.9819513568
MESH:D008579 Meningioma Ethylnitrosourea 5.3717943659
MESH:D008591 Meningomyelocele Tretinoin 3.8416940565
MESH:D008654 Mesothelioma Doxorubicin 2.7917638057
MESH:D008708 Methemoglobinemia Phenacetin 4.4016296465 4834387 3537620 1949026
MESH:D008881 Migraine Disorders Valproic Acid 2.7518803445 18765137
MESH:D028361 Mitochondrial Diseases Doxorubicin 3.9615792986
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 6.9616381670
MESH:D009062 Mouth Neoplasms Fluorouracil 6.9616757204 18986760
MESH:D052016 Mucositis Doxorubicin 4.1917415656
MESH:D009101 Multiple Myeloma arsenic trioxide 9.6111468182 19417148 19549372 14977855 15949261
MESH:D009101 Multiple Myeloma decitabine 9.6118172295
MESH:D009101 Multiple Myeloma Dexamethasone 9.6115867202 15744524 16118317
MESH:D009135 Muscular Diseases Bezafibrate 8.7916239165
MESH:D009135 Muscular Diseases pirinixic acid 8.7916239165
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 3.498888407
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.0618349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 19.1216882451 16105982
MESH:D009190 Myelodysplastic Syndromes decitabine 19.1219157545 18608210 19010910 16882708
MESH:D009190 Myelodysplastic Syndromes Dexamethasone 19.129809623
MESH:D009190 Myelodysplastic Syndromes Tretinoin 19.1217596541
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 19.1217596541
MESH:D009203 Myocardial Infarction Doxorubicin 7.7919429709 15857846
MESH:D009203 Myocardial Infarction Genistein 7.7917141266
MESH:D009203 Myocardial Infarction pirinixic acid 7.7919151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.5412213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 11.4516810080
MESH:D015428 Myocardial Reperfusion Injury Genistein 11.4517141266
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 11.4516411023
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 3.8717484760
MESH:D009336 Necrosis 2,6-dinitrotoluene 3.267678174 18551238
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.3916624393
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 11.343581430 9029167
MESH:D009362 Neoplasm Metastasis Doxorubicin 11.3418259882
MESH:D009362 Neoplasm Metastasis quinoline 11.34598648
MESH:D009362 Neoplasm Metastasis Tamoxifen 11.3419393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.2919410462
MESH:D009369 Neoplasms Benzo(a)pyrene 15.4711141357
MESH:D009369 Neoplasms decitabine 15.4719470736 19116145 17925555
MESH:D009369 Neoplasms Diethylstilbestrol 15.4715313581
MESH:D009369 Neoplasms Fluorouracil 15.4718239605 18600527 16928823
MESH:D009369 Neoplasms pirinixic acid 15.4717405874
MESH:D009369 Neoplasms Tretinoin 15.4716594593 16946489
MESH:D009374 Neoplasms, Experimental Ethylnitrosourea 3.8216707424
MESH:D009376 Neoplasms, Hormone-Dependent bexarotene 8.9019196722
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 8.9019189210 19196722 19200415
MESH:D009389 Neovascularization, Pathologic Estradiol 3.1417289903
MESH:D009395 Nephritis, Interstitial Tetracycline 4.189884423
MESH:D009401 Nephrosis Doxorubicin 4.1816899518 16636307
MESH:D009404 Nephrotic Syndrome Doxorubicin 3.4915640375 16889571
MESH:D009421 Nervous System Malformations Diethylstilbestrol 24.7211399458
MESH:D009421 Nervous System Malformations Estradiol 24.7211399458 16427766
MESH:D009421 Nervous System Malformations Genistein 24.7216427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 24.7214600291
MESH:D009421 Nervous System Malformations Tretinoin 24.729125849
MESH:D009436 Neural Tube Defects arsenic trioxide 9.7510525206
MESH:D009436 Neural Tube Defects Tretinoin 9.759142499
MESH:D009436 Neural Tube Defects Valproic Acid 9.7516359493 8888407
MESH:D009442 Neurilemmoma Ethylnitrosourea 4.8116651423 16003739 17160924
MESH:D009447 Neuroblastoma Doxorubicin 2.9215555623
MESH:D019636 Neurodegenerative Diseases Acetaminophen 11.2518514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 11.2520387270
MESH:D019636 Neurodegenerative Diseases Sulindac 11.2516850258 17266991
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.5020387270
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.0116436463
MESH:D009765 Obesity Dietary Fats 3.8021332399 16723640 17217161 18674790 19632207 18457598 20132043 20518802 11836018
MESH:D009765 Obesity pirinixic acid 3.8020558911
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 2.9116049721
MESH:D009837 Oligodendroglioma Ethylnitrosourea 5.3717160924
MESH:D010018 Osteomalacia Phenobarbital 3.7617016548
MESH:D010024 Osteoporosis Genistein 2.8619401787
MESH:D015663 Osteoporosis, Postmenopausal Genistein 3.5316169203
MESH:D012516 Osteosarcoma Doxorubicin 3.6315930896
MESH:D010051 Ovarian Neoplasms arsenic trioxide 15.8319769630 16624393 12452020
MESH:D010051 Ovarian Neoplasms decitabine 15.8319331143 19259094
MESH:D010051 Ovarian Neoplasms Estradiol 15.8319401270
MESH:D010051 Ovarian Neoplasms Genistein 15.8319005980
MESH:D010051 Ovarian Neoplasms Progesterone 15.8317393432 16525653
MESH:D010051 Ovarian Neoplasms Tretinoin 15.8316936753
MESH:D010146 Pain Acetaminophen 8.4916870215
MESH:D010146 Pain Sulindac 8.493291741
MESH:D010146 Pain Tretinoin 8.4916870215
MESH:D010190 Pancreatic Neoplasms 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 33.0812384795
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 33.0815580305
MESH:D010190 Pancreatic Neoplasms decitabine 33.0819294695
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 33.0816540662
MESH:D010190 Pancreatic Neoplasms Etoposide 33.0819003803
MESH:D010190 Pancreatic Neoplasms Fluorouracil 33.0815113037 16929163 16500647 19003803
MESH:D010190 Pancreatic Neoplasms Mitomycin 33.0815113037
MESH:D010190 Pancreatic Neoplasms Phenobarbital 33.0816965848
MESH:D010190 Pancreatic Neoplasms Sulindac 33.0816820089 11504793
MESH:D010190 Pancreatic Neoplasms Tretinoin 33.0815976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.1311578682
MESH:D010235 Paraganglioma arsenic trioxide 3.6119927285
MESH:D010382 Peliosis Hepatis 1-Naphthylisothiocyanate 11.7520133375
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 11.7512520081
MESH:D010391 Pemphigoid, Bullous Tetracycline 4.8211026799
MESH:D010538 Peritonitis Thioglycolates 5.1619641140 19804847 16751407 11985352 15707874 19180231 18628355
MESH:D003557 Phyllodes Tumor Doxorubicin 4.5417983394
MESH:D010900 Pituitary Diseases Diethylstilbestrol 4.5614722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 4.0815687265 16977796
MESH:D010997 Pleural Neoplasms Doxorubicin 4.5417638057
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 2.9918163543
MESH:D011230 Precancerous Conditions Diethylnitrosamine 7.392563599
MESH:D011230 Precancerous Conditions Phenobarbital 7.392563599
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Dexamethasone 3.1821297632
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 18.3417184923
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 18.3411222880 11399792 11896295 11118676
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 18.3420603192
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 18.3418220299 18042343 19015723
MESH:D055728 Primary Myelofibrosis decitabine 4.1417616702
MESH:D017096 Prion Diseases Tetracycline 4.8110903871
MESH:D011469 Prostatic Diseases vinclozolin 4.3318220299
MESH:D011470 Prostatic Hyperplasia Calcitriol 4.1815572423
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.3420887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 3.7719131511
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 3.7717292933
MESH:D011471 Prostatic Neoplasms Calcitriol 3.7718247401 16644109 15754350 16289102 12479363
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 3.7717136230 15046698 15846301
MESH:D011471 Prostatic Neoplasms Doxorubicin 3.7716868541 18437689 15749863 16729912 16888761 15897917
MESH:D011471 Prostatic Neoplasms Estradiol 3.7716740699
MESH:D011471 Prostatic Neoplasms Etoposide 3.7717172428
MESH:D011471 Prostatic Neoplasms Fluorouracil 3.7718626508 19082440
MESH:D011471 Prostatic Neoplasms Flurbiprofen 3.7717409433
MESH:D011471 Prostatic Neoplasms Genistein 3.7715256057 15378649 16925846
MESH:D011471 Prostatic Neoplasms Tamoxifen 3.7715067354
MESH:D011472 Prostatitis vinclozolin 4.3318629315
MESH:D011507 Proteinuria Tretinoin 3.0516636307
MESH:D011537 Pruritus Ethinyl Estradiol 8.0415861022 16919318
MESH:D011537 Pruritus Naloxone 8.0415861022
MESH:D019310 Pseudolymphoma Phenobarbital 10.1512752131
MESH:D019310 Pseudolymphoma Valproic Acid 10.1512752131 11422049
MESH:D011625 Pterygium Tretinoin 4.1916723453
MESH:D029424 Pulmonary Disease, Chronic Obstructive Theophylline 4.6718983928
MESH:D012004 Rectal Neoplasms Fluorouracil 3.5015538739 18286688 16160472 18722050
MESH:D051437 Renal Insufficiency Doxorubicin 3.6417922066
MESH:D015427 Reperfusion Injury pirinixic acid 2.0619058328
MESH:D012128 Respiratory Distress Syndrome, Adult Dexamethasone 3.4718379247 11700416
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.2618990726
MESH:D012208 Rhabdomyosarcoma decitabine 15.3119155313
MESH:D012208 Rhabdomyosarcoma Tretinoin 15.3116116481 16283617
MESH:D012208 Rhabdomyosarcoma Valproic Acid 15.3119155313
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.6118045962
MESH:D012509 Sarcoma Doxorubicin 3.4715625365 17203757 16767912 18313854 17710206 15675481
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 14.0316646077
MESH:D012512 Sarcoma, Ewing's Doxorubicin 14.0316326096 14601052
MESH:D012512 Sarcoma, Ewing's Etoposide 14.0314601052
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.1917846226
MESH:D012559 Schizophrenia Valproic Acid 1.9815737665 19110320
MESH:D012640 Seizures 2,6-dinitrotoluene 7.3818551238
MESH:D012640 Seizures Phenobarbital 7.384039156 11442880 3137016 16876388
MESH:D012640 Seizures Valproic Acid 7.3811044598 16876388 3137016 15475178 1511512 17978042 14763951 11738929
MESH:D003294 Seizures, Febrile Phenobarbital 4.226407741
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 10.9219755658 10029692
MESH:D012878 Skin Neoplasms Doxorubicin 10.9215692506
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 10.9216192470
MESH:D012878 Skin Neoplasms Tretinoin 10.9216467112
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 3.9817203757 16767912 15625365
MESH:D013088 Spermatocele Diethylstilbestrol 16.6016709447 16002989
MESH:D013088 Spermatocele Ethinyl Estradiol 16.6016709447
MESH:D013088 Spermatocele Tamoxifen 16.6016709447
MESH:D013119 Spinal Cord Injuries Progesterone 8.8816503802 15862959
MESH:D013119 Spinal Cord Injuries Tamoxifen 8.8819457130
MESH:D016135 Spinal Dysraphism Valproic Acid 3.3119490988
MESH:D013158 Splenic Diseases Dimethylnitrosamine 4.6612587719
MESH:D013226 Status Epilepticus Valproic Acid 3.9312833885
MESH:D013272 Stomach Diseases Dexamethasone 3.7215472012
MESH:D013274 Stomach Neoplasms arsenic trioxide 9.0217007042
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 9.0220155912 2093021
MESH:D013274 Stomach Neoplasms decitabine 9.0219037991
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 9.0218456281
MESH:D013274 Stomach Neoplasms Dimethylnitrosamine 9.0216033868
MESH:D013274 Stomach Neoplasms Fluorouracil 9.0219015929 16424979 18567086 17522103 19084572 17498489 16951190 18396642 15786421 17172411
MESH:D013274 Stomach Neoplasms Tretinoin 9.0217261132
MESH:D013276 Stomach Ulcer Dexamethasone 2.9715138204
MESH:D013436 Sulfhemoglobinemia Phenacetin 5.94978859
MESH:D013921 Thrombocytopenia 1-Naphthylisothiocyanate 4.2320133375
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.0611994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.6415669648
MESH:D013953 Thymus Neoplasms Ethylnitrosourea 4.5615790496
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.2912697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 22.0019014326
MESH:D013964 Thyroid Neoplasms decitabine 22.0017967635
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 22.007505956
MESH:D013964 Thyroid Neoplasms Doxorubicin 22.0017909728 16010429
MESH:D013964 Thyroid Neoplasms Phenobarbital 22.001399818
MESH:D013964 Thyroid Neoplasms Tretinoin 22.0016026305 17045167
MESH:D013978 Tibial Fractures Estradiol 4.0719048282
MESH:D014062 Tongue Neoplasms Fluorouracil 8.0816280240
MESH:D014062 Tongue Neoplasms Tretinoin 8.0816051514
MESH:D016171 Torsades de Pointes arsenic trioxide 3.3615213294
MESH:D014178 Translocation, Genetic Valproic Acid 4.6217262798
MESH:D014376 Tuberculosis Tretinoin 2.8316040207
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 3.923119515
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 23.6416049721
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 23.6412973940 20435036 12845720 11780464
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 23.6417053015
MESH:D001749 Urinary Bladder Neoplasms decitabine 23.6419087683 17616700
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 23.6416452187 17306315 16712894
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 23.6417653716
MESH:D001749 Urinary Bladder Neoplasms Phenacetin 23.6411144890
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 23.6417572228 16712894 8653321
MESH:D014564 Urogenital Abnormalities Valproic Acid 4.058888407
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 3.7210091137
MESH:D014581 Urticaria Acetaminophen 2.4310982225
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 12.8616175088
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 12.8616803524
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 12.8616129372
MESH:D014591 Uterine Diseases Diethylstilbestrol 4.5614652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 12.8415809267 16690809
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 12.8414692618
MESH:D014594 Uterine Neoplasms Sulindac 12.8418645019
MESH:D014604 Uveal Neoplasms decitabine 10.7917785578
MESH:D014604 Uveal Neoplasms Tretinoin 10.7916752155
MESH:D014605 Uveitis Dexamethasone 4.211336536
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 3.8516002989 16513791
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 3.9812125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.0014671159 15869587
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 3.6417334414 17678736 16364871 17638931
MESH:D014820 Vitiligo Tretinoin 3.4916761959
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.6315886252
MESH:D015430 Weight Gain Dietary Fats 3.2316723640
MESH:D009396 Wilms Tumor Tretinoin 3.4516287080
Pathway ID Pathway Name
REACT:6900 Signaling in Immune system
Pharmacogenomics Knowledge Base Top
Drug Bank Top
Drugbank ID Action Drug Name Description
DB01827 - 2,3,5,6-Tetrafluoro-4-Methoxy-Benzamide
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Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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