Annotation Detail for LHB
Basic Information Top
Gene Symbol: | LHB ( CGB4,LSH-B,hLHB ) |
---|---|
Gene Full Name: | luteinizing hormone beta polypeptide |
Band: | 19q13.3 |
Quick Links | Entrez ID:3972; OMIM: 152780; Uniprot ID:LSHB_HUMAN; ENSEMBL ID: ENSG00000104826; HGNC ID: 6584 |
Relate to Another Database: | SFARIGene; denovo-db |
Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
---|---|---|---|---|
C070379 | 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester | 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Dinoprost inhibits the reaction [LHB protein results in increased secretion of Progesterone]] | decreases reaction|increases secretion | 17760987 |
C070379 | 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester | 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [LHB protein results in increased secretion of Progesterone] | decreases reaction|increases secretion | 17760987 |
C420062 | 1-(2-methylbenzoxazol-6-yl)-3-(1,5)naphthyridin-4-yl urea | [1-(2-methylbenzoxazol-6-yl)-3-(1,5)naphthyridin-4-yl urea co-treated with JNJ-10397049] results in decreased expression of LHB protein | affects cotreatment|decreases expression | 17638707 |
C014024 | 2,4,5,2',4',5'-hexachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl promotes the reaction [LHB protein results in increased secretion of OXT protein] | increases reaction|increases secretion | 16780177 |
C028451 | 3,4,3',4'-tetrachlorobiphenyl | 3,4,3',4'-tetrachlorobiphenyl affects the reaction [LHB protein results in increased secretion of OXT protein] | affects reaction|increases secretion | 16780177 |
C028451 | 3,4,3',4'-tetrachlorobiphenyl | 3,4,3',4'-tetrachlorobiphenyl inhibits the reaction [LHB protein results in increased secretion of Progesterone] | decreases reaction|increases secretion | 16967098 |
C023035 | 3,4,5,3',4'-pentachlorobiphenyl | 3,4,5,3',4'-pentachlorobiphenyl affects the reaction [LHB protein results in increased secretion of OXT protein] | affects reaction|increases secretion | 16780177 |
C023035 | 3,4,5,3',4'-pentachlorobiphenyl | 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [LHB protein results in increased secretion of Progesterone] | decreases reaction|increases secretion | 16967098 |
C009505 | 4,4'-diaminodiphenylmethane | 4,4'-diaminodiphenylmethane results in increased expression of LHB mRNA | increases expression | 18648102 |
C041594 | 4-nonylphenol | 4-nonylphenol affects the expression of LHB protein | affects expression | 15888928 |
C041594 | 4-nonylphenol | 4-nonylphenol results in decreased expression of and results in decreased secretion of LHB protein | decreases expression|decreases secretion | 17033158 |
C105260 | 4-tert-octylphenol | 4-tert-octylphenol affects the expression of LHB protein | affects expression | 15888928 |
C105260 | 4-tert-octylphenol | 4-tert-octylphenol results in decreased expression of LHB protein | decreases expression | 17033158 |
C119737 | 8-prenylnaringenin | 8-prenylnaringenin results in decreased expression of LHB mRNA | decreases expression | 16522720 |
C119737 | 8-prenylnaringenin | 8-prenylnaringenin results in decreased expression of LHB protein | decreases expression | 16522720 |
C034632 | ABVD protocol | ABVD protocol results in increased expression of LHB protein | increases expression | 17965791 |
D000082 | Acetaminophen | Acetaminophen affects the expression of LHB mRNA | affects expression | 17562736 |
D053959 | Alpha-Amanitin | Alpha-Amanitin inhibits the reaction [LHB protein results in increased expression of NR4A1 mRNA] | decreases reaction|increases expression | 11416027 |
C069206 | alpha helical corticotropin-releasing hormone | alpha helical corticotropin-releasing hormone results in decreased secretion of LHB protein | decreases secretion | 15486230 |
D000643 | Ammonium Chloride | Ammonium Chloride affects the expression of LHB mRNA | affects expression | 16483693 |
C006632 | arsenic trioxide | arsenic trioxide results in decreased expression of LHB protein | decreases expression | 18630931 |
D001205 | Ascorbic Acid | Ascorbic Acid inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of LHB protein] | decreases expression|decreases reaction | 16248992 16298753 17280759 |
C120841 | astressin B | astressin B inhibits the reaction [GHRL protein results in decreased expression of LHB protein] | decreases expression|decreases reaction | 18063681 |
C120841 | astressin B | astressin B inhibits the reaction [Lipopolysaccharides results in decreased expression of LHB protein] | decreases expression|decreases reaction | 17082255 |
D001280 | Atrazine | Atrazine results in increased expression of LHB mRNA | increases expression | 18461179 |
D001280 | Atrazine | NR5A1 protein affects the reaction [Atrazine results in increased expression of LHB mRNA] | affects reaction|increases expression | 18461179 |
D001280 | Atrazine | SGK1 protein affects the reaction [Atrazine results in increased expression of LHB mRNA] | affects reaction|increases expression | 18461179 |
D001280 | Atrazine | Atrazine inhibits the reaction [[estradiol 3-benzoate co-treated with Progesterone] results in increased secretion of LHB protein] | affects cotreatment|decreases reaction|increases secretion | 15056801 |
D001280 | Atrazine | Atrazine inhibits the reaction [estradiol 3-benzoate results in increased secretion of LHB protein] | decreases reaction|increases secretion | 10696778 |
D001280 | Atrazine | Atrazine results in decreased secretion of LHB protein | decreases secretion | 15056801 10696778 |
D001280 | Atrazine | GNRH1 protein inhibits the reaction [Atrazine results in decreased secretion of LHB protein] | decreases reaction|decreases secretion | 10696778 |
C006780 | bisphenol A | bisphenol A results in increased expression of LHB mRNA | increases expression | 20647052 |
C006780 | bisphenol A | LHB protein affects the reaction [bisphenol A results in decreased expression of CPLX1 mRNA] | affects reaction|decreases expression | 17706920 |
C006780 | bisphenol A | LHB protein affects the reaction [bisphenol A results in decreased expression of EVX2 mRNA] | affects reaction|decreases expression | 17706920 |
C006780 | bisphenol A | LHB protein affects the reaction [bisphenol A results in decreased expression of GGN mRNA] | affects reaction|decreases expression | 17706920 |
C006780 | bisphenol A | LHB protein affects the reaction [bisphenol A results in decreased expression of MARCKS mRNA] | affects reaction|decreases expression | 17706920 |
C006780 | bisphenol A | LHB protein affects the reaction [bisphenol A results in decreased expression of MS4A6C mRNA] | affects reaction|decreases expression | 17706920 |
C006780 | bisphenol A | LHB protein affects the reaction [bisphenol A results in decreased expression of PPP1R3A mRNA] | affects reaction|decreases expression | 17706920 |
C006780 | bisphenol A | LHB protein affects the reaction [bisphenol A results in decreased expression of SASS6 mRNA] | affects reaction|decreases expression | 17706920 |
C006780 | bisphenol A | LHB protein affects the reaction [bisphenol A results in decreased expression of TPX2 mRNA] | affects reaction|decreases expression | 17706920 |
C006780 | bisphenol A | LHB protein affects the reaction [bisphenol A results in decreased expression of WDR19 mRNA] | affects reaction|decreases expression | 17706920 |
C006780 | bisphenol A | LHB protein affects the reaction [bisphenol A results in decreased expression of WDR51B mRNA] | affects reaction|decreases expression | 17706920 |
C006780 | bisphenol A | LHB protein affects the reaction [bisphenol A results in increased expression of ATP6V1E2 mRNA] | affects reaction|increases expression | 17706920 |
C006780 | bisphenol A | LHB protein affects the reaction [bisphenol A results in increased expression of BBS4 mRNA] | affects reaction|increases expression | 17706920 |
C006780 | bisphenol A | LHB protein affects the reaction [bisphenol A results in increased expression of CYP7A1 mRNA] | affects reaction|increases expression | 17706920 |
C006780 | bisphenol A | LHB protein affects the reaction [bisphenol A results in increased expression of JRK mRNA] | affects reaction|increases expression | 17706920 |
C006780 | bisphenol A | LHB protein affects the reaction [bisphenol A results in increased expression of KLHL18 mRNA] | affects reaction|increases expression | 17706920 |
C006780 | bisphenol A | LHB protein affects the reaction [bisphenol A results in increased expression of PEX2 mRNA] | affects reaction|increases expression | 17706920 |
C006780 | bisphenol A | bisphenol A results in decreased expression of LHB mRNA | decreases expression | 14605012 |
C006780 | bisphenol A | bisphenol A results in decreased expression of LHB protein | decreases expression | 20144698 |
C025191 | bromodichloromethane | bromodichloromethane results in decreased secretion of LHB protein | decreases secretion | 14657523 17344021 |
D002118 | Calcium | Calcium inhibits the reaction [LHB protein results in increased secretion of Progesterone] | decreases reaction|increases secretion | 17760987 |
C062876 | cetrorelix | cetrorelix results in decreased expression of LHB protein | decreases expression | 16914592 |
C062876 | cetrorelix | cetrorelix results in decreased expression of LHB protein | decreases expression | 17638707 |
D020111 | Chlorodiphenyl (54% Chlorine) | Ascorbic Acid inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of LHB protein] | decreases expression|decreases reaction | 17280759 16248992 16298753 |
D020111 | Chlorodiphenyl (54% Chlorine) | Chlorodiphenyl (54% Chlorine) results in decreased expression of LHB protein | decreases expression | 16248992 16298753 17280759 |
D020111 | Chlorodiphenyl (54% Chlorine) | Vitamin E inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of LHB protein] | decreases expression|decreases reaction | 16298753 17280759 |
D002994 | Clofibrate | PPARA protein affects the reaction [Clofibrate results in decreased expression of LHB mRNA] | affects reaction|decreases expression | 17585979 |
D003277 | Contraceptives, Oral, Combined | [LHRH, Ala(6)-Gly(10)-ethylamide- co-treated with Contraceptives, Oral, Combined] results in decreased expression of LHB protein | affects cotreatment|decreases expression | 11228061 |
D003300 | Copper | [Copper binds to GNRH1 protein] which results in increased secretion of LHB protein | affects binding|increases secretion | 16892001 |
D003513 | Cycloheximide | Cycloheximide promotes the reaction [LHB protein results in increased expression of NR4A1 mRNA] | increases expression|increases reaction | 11416027 |
D017373 | Cyproterone Acetate | [Ethinyl Estradiol co-treated with Cyproterone Acetate] results in decreased expression of LHB protein | affects cotreatment|decreases expression | 16002536 |
D017135 | Desogestrel | [Ethinyl Estradiol co-treated with Desogestrel] results in decreased expression of LHB protein | affects cotreatment|decreases expression | 17105841 |
D017135 | Desogestrel | Simvastatin promotes the reaction [[Ethinyl Estradiol co-treated with Desogestrel] results in decreased expression of LHB protein] | affects cotreatment|decreases expression|increases reaction | 17105841 |
D003907 | Dexamethasone | Dexamethasone results in decreased expression of LHB mRNA | decreases expression | 16675544 |
D004051 | Diethylhexyl Phthalate | Diethylhexyl Phthalate results in decreased expression of LHB protein | decreases expression | 16400681 |
D004054 | Diethylstilbestrol | Diethylstilbestrol results in decreased expression of LHB protein | decreases expression | 17213693 16468032 |
D004054 | Diethylstilbestrol | Diethylstilbestrol affects the expression of LHB protein | affects expression | 15888928 |
D004054 | Diethylstilbestrol | Diethylstilbestrol results in increased expression of LHB protein | increases expression | 16537657 |
D011397 | Promegestone | Promegestone results in decreased expression of LHB mRNA | decreases expression | 16675544 |
C007630 | estradiol 17 beta-cypionate | estradiol 17 beta-cypionate promotes the reaction [[Tetrachlorodibenzodioxin co-treated with Gonadotropins, Equine] results in increased expression of LHB protein] | affects cotreatment|increases expression|increases reaction | 12606454 |
C007630 | estradiol 17 beta-cypionate | estradiol 17 beta-cypionate promotes the reaction [[Tetrachlorodibenzodioxin co-treated with Gonadotropins, Equine] results in increased secretion of LHB protein] | affects cotreatment|increases reaction|increases secretion | 12606454 |
C074283 | estradiol 3-benzoate | estradiol 3-benzoate results in decreased expression of LHB mRNA | decreases expression | 15223135 |
C074283 | estradiol 3-benzoate | Atrazine inhibits the reaction [[estradiol 3-benzoate co-treated with Progesterone] results in increased secretion of LHB protein] | affects cotreatment|decreases reaction|increases secretion | 15056801 |
C074283 | estradiol 3-benzoate | Atrazine inhibits the reaction [estradiol 3-benzoate results in increased secretion of LHB protein] | decreases reaction|increases secretion | 10696778 |
C074283 | estradiol 3-benzoate | estradiol 3-benzoate results in decreased expression of LHB mRNA | decreases expression | 16614383 |
C074283 | estradiol 3-benzoate | estradiol 3-benzoate results in decreased secretion of LHB protein | decreases secretion | 16614383 |
C074283 | estradiol 3-benzoate | estradiol 3-benzoate results in increased secretion of LHB protein | increases secretion | 17398000 10696778 |
C074283 | estradiol 3-benzoate | Raloxifene inhibits the reaction [estradiol 3-benzoate results in increased secretion of LHB protein] | decreases reaction|increases secretion | 17398000 |
D004958 | Estradiol | Estradiol results in increased expression of LHB | increases expression | 19456401 |
D004958 | Estradiol | Estradiol results in increased expression of LHB mRNA | increases expression | 20647052 |
D004958 | Estradiol | Estradiol results in decreased secretion of LHB protein | decreases secretion | 17629525 |
D004958 | Estradiol | Estradiol results in increased expression of LHB protein | increases expression | 15796768 |
D004958 | Estradiol | [Estradiol co-treated with Progesterone] results in increased expression of LHB protein | affects cotreatment|increases expression | 17640482 |
D004958 | Estradiol | Estradiol results in decreased expression of LHB mRNA | decreases expression | 16614383 16522720 |
D004958 | Estradiol | Estradiol results in decreased expression of LHB protein | decreases expression | 16522720 20144698 |
D004958 | Estradiol | Estradiol results in decreased secretion of LHB protein | decreases secretion | 16614383 |
D004958 | Estradiol | nociceptin (1-13) amide inhibits the reaction [PNOC protein inhibits the reaction [[Estradiol co-treated with Progesterone] results in increased expression of LHB protein]] | affects cotreatment|decreases reaction|increases expression | 17640482 |
D004958 | Estradiol | PNOC protein inhibits the reaction [[Estradiol co-treated with Progesterone] results in increased expression of LHB protein] | affects cotreatment|decreases reaction|increases expression | 17640482 |
C043090 | estradiol-bovine serum albumin | estradiol-bovine serum albumin results in decreased secretion of LHB protein | decreases secretion | 17629525 |
C015854 | estradiol valerate | estradiol valerate results in decreased expression of LHB protein | decreases expression | 10843175 |
D004966 | Estrogens, Conjugated (USP) | Estrogens, Conjugated (USP) results in decreased expression of LHB protein | decreases expression | 10843175 |
D000431 | Ethanol | Ethanol results in decreased expression of LHB protein | decreases expression | 7592674 |
D004997 | Ethinyl Estradiol | [Ethinyl Estradiol co-treated with Cyproterone Acetate] results in decreased expression of LHB protein | affects cotreatment|decreases expression | 16002536 |
D004997 | Ethinyl Estradiol | [Ethinyl Estradiol co-treated with Desogestrel] results in decreased expression of LHB protein | affects cotreatment|decreases expression | 17105841 |
D004997 | Ethinyl Estradiol | [Ethinyl Estradiol co-treated with Levonorgestrel] results in decreased expression of LHB protein | affects cotreatment|decreases expression | 16291413 |
D004997 | Ethinyl Estradiol | Ethinyl Estradiol results in decreased expression of LHB protein | decreases expression | 11907703 10843175 |
D004997 | Ethinyl Estradiol | Simvastatin promotes the reaction [[Ethinyl Estradiol co-treated with Desogestrel] results in decreased expression of LHB protein] | affects cotreatment|decreases expression|increases reaction | 17105841 |
D004997 | Ethinyl Estradiol | SPP301 affects the reaction [[Ethinyl Estradiol co-treated with Levonorgestrel] affects the expression of LHB protein] | affects cotreatment|affects expression|affects reaction | 17190377 |
D004997 | Ethinyl Estradiol | Ethinyl Estradiol results in decreased expression of LHB mRNA | decreases expression | 16330033 |
C442659 | ethinyl estradiol-desogestrel combination | ethinyl estradiol-desogestrel combination results in decreased expression of LHB protein | decreases expression | 17105841 |
C442659 | ethinyl estradiol-desogestrel combination | Simvastatin promotes the reaction [ethinyl estradiol-desogestrel combination results in decreased expression of LHB protein] | decreases expression|increases reaction | 17105841 |
D005485 | Flutamide | Flutamide results in decreased expression of LHB protein | decreases expression | 16735550 |
D005485 | Flutamide | [LHRH, Ala(6)-Gly(10)-ethylamide- co-treated with Flutamide] results in decreased expression of LHB protein | affects cotreatment|decreases expression | 11228061 |
D005485 | Flutamide | Flutamide affects the expression of LHB protein | affects expression | 15519604 |
D005485 | Flutamide | Flutamide inhibits the reaction [Testosterone Propionate results in decreased expression of LHB protein] | decreases expression|decreases reaction | 11376863 |
D005485 | Flutamide | Flutamide results in increased expression of LHB mRNA | increases expression | 14967917 |
D005485 | Flutamide | Flutamide results in increased expression of LHB protein | increases expression | 16537657 |
D006064 | Gonadotropins, Equine | estradiol 17 beta-cypionate promotes the reaction [[Tetrachlorodibenzodioxin co-treated with Gonadotropins, Equine] results in increased expression of LHB protein] | affects cotreatment|increases expression|increases reaction | 12606454 |
D006064 | Gonadotropins, Equine | estradiol 17 beta-cypionate promotes the reaction [[Tetrachlorodibenzodioxin co-treated with Gonadotropins, Equine] results in increased secretion of LHB protein] | affects cotreatment|increases reaction|increases secretion | 12606454 |
D006064 | Gonadotropins, Equine | Mifepristone promotes the reaction [[Tetrachlorodibenzodioxin co-treated with Gonadotropins, Equine] results in increased expression of LHB protein] | affects cotreatment|increases expression|increases reaction | 12606454 |
D006064 | Gonadotropins, Equine | Pentobarbital inhibits the reaction [[Tetrachlorodibenzodioxin co-treated with Gonadotropins, Equine] results in increased expression of LHB protein] | affects cotreatment|decreases reaction|increases expression | 12606454 |
D006064 | Gonadotropins, Equine | [Tetrachlorodibenzodioxin co-treated with Gonadotropins, Equine] results in increased expression of LHB protein | affects cotreatment|increases expression | 12606454 |
C524573 | JNJ-10397049 | [1-(2-methylbenzoxazol-6-yl)-3-(1,5)naphthyridin-4-yl urea co-treated with JNJ-10397049] results in decreased expression of LHB protein | affects cotreatment|decreases expression | 17638707 |
C524573 | JNJ-10397049 | JNJ-10397049 results in decreased expression of LHB protein | decreases expression | 17638707 |
C067431 | letrozole | letrozole results in increased expression of LHB protein | increases expression | 16046582 |
C083781 | LHRH, Ala(6)-Gly(10)-ethylamide- | [LHRH, Ala(6)-Gly(10)-ethylamide- co-treated with Contraceptives, Oral, Combined] results in decreased expression of LHB protein | affects cotreatment|decreases expression | 11228061 |
C083781 | LHRH, Ala(6)-Gly(10)-ethylamide- | [LHRH, Ala(6)-Gly(10)-ethylamide- co-treated with Flutamide] results in decreased expression of LHB protein | affects cotreatment|decreases expression | 11228061 |
C083781 | LHRH, Ala(6)-Gly(10)-ethylamide- | LHRH, Ala(6)-Gly(10)-ethylamide- results in decreased expression of LHB protein | decreases expression | 11228061 |
D008070 | Lipopolysaccharides | astressin B inhibits the reaction [Lipopolysaccharides results in decreased expression of LHB protein] | decreases expression|decreases reaction | 17082255 |
D008070 | Lipopolysaccharides | Lipopolysaccharides results in decreased expression of LHB protein | decreases expression | 17082255 |
D008070 | Lipopolysaccharides | Lipopolysaccharides results in decreased expression of LHB protein | decreases expression | 12207160 |
C008376 | mestanolone | mestanolone results in decreased expression of LHB mRNA | decreases expression | 16330033 |
D008714 | Methiocarb | Methiocarb results in decreased expression of LHB protein | decreases expression | 15519604 |
D008724 | Methomyl | Methomyl results in increased expression of LHB protein | increases expression | 11516254 |
C013598 | methoxyacetic acid | methoxyacetic acid affects the secretion of LHB protein | affects secretion | 1898883 |
D015741 | Metribolone | Metribolone results in decreased expression of LHB mRNA | decreases expression | 16675544 |
D015735 | Mifepristone | Mifepristone promotes the reaction [[Tetrachlorodibenzodioxin co-treated with Gonadotropins, Equine] results in increased expression of LHB protein] | affects cotreatment|increases expression|increases reaction | 12606454 |
C009821 | molinate | molinate affects the secretion of LHB protein | affects secretion | 15601673 |
C014553 | MOPP protocol | MOPP protocol affects the expression of LHB protein | affects expression | 14752856 |
C014553 | MOPP protocol | MOPP protocol results in increased expression of LHB protein | increases expression | 17981817 17965791 |
C063509 | N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide | N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [LHB protein results in increased expression of AREG mRNA] | decreases reaction|increases expression | 15967414 |
C063509 | N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide | N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [LHB protein results in increased expression of AREG protein] | decreases reaction|increases expression | 15967414 |
C063509 | N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide | N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [LHB protein results in increased secretion of Progesterone] | decreases reaction|increases secretion | 15967414 |
D009532 | Nickel | [Nickel binds to GNRH1 protein] which results in increased secretion of LHB protein | affects binding|increases secretion | 16892001 |
D009583 | Nitrofurazone | Nitrofurazone inhibits the reaction [GNRH1 protein results in increased secretion of LHB protein] | decreases reaction|increases secretion | 3126094 |
D009583 | Nitrofurazone | Nitrofurazone results in decreased expression of LHB protein | decreases expression | 3126094 |
C439964 | nociceptin (1-13) amide | nociceptin (1-13) amide inhibits the reaction [PNOC protein inhibits the reaction [[Estradiol co-treated with Progesterone] results in increased expression of LHB protein]] | affects cotreatment|decreases reaction|increases expression | 17640482 |
D016912 | Levonorgestrel | [Ethinyl Estradiol co-treated with Levonorgestrel] results in decreased expression of LHB protein | affects cotreatment|decreases expression | 16291413 |
D016912 | Levonorgestrel | SPP301 affects the reaction [[Ethinyl Estradiol co-treated with Levonorgestrel] affects the expression of LHB protein] | affects cotreatment|affects expression|affects reaction | 17190377 |
D010424 | Pentobarbital | Pentobarbital inhibits the reaction [[Tetrachlorodibenzodioxin co-treated with Gonadotropins, Equine] results in increased expression of LHB protein] | affects cotreatment|decreases reaction|increases expression | 12606454 |
D010424 | Pentobarbital | Pentobarbital results in decreased expression of LHB protein | decreases expression | 17638707 |
C045362 | prochloraz | prochloraz results in increased expression of LHB protein | increases expression | 12377983 |
C035988 | procymidone | procymidone results in increased expression of LHB protein | increases expression | 12563111 |
C035988 | procymidone | [vinclozolin co-treated with procymidone] results in increased expression of LHB protein | affects cotreatment|increases expression | 12563111 |
D011374 | Progesterone | 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Dinoprost inhibits the reaction [LHB protein results in increased secretion of Progesterone]] | decreases reaction|increases secretion | 17760987 |
D011374 | Progesterone | 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [LHB protein results in increased secretion of Progesterone] | decreases reaction|increases secretion | 17760987 |
D011374 | Progesterone | 3,4,3',4'-tetrachlorobiphenyl inhibits the reaction [LHB protein results in increased secretion of Progesterone] | decreases reaction|increases secretion | 16967098 |
D011374 | Progesterone | 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [LHB protein results in increased secretion of Progesterone] | decreases reaction|increases secretion | 16967098 |
D011374 | Progesterone | Calcium inhibits the reaction [LHB protein results in increased secretion of Progesterone] | decreases reaction|increases secretion | 17760987 |
D011374 | Progesterone | Dinoprost inhibits the reaction [LHB protein results in increased abundance of Progesterone] | decreases reaction|increases abundance | 15601909 |
D011374 | Progesterone | Dinoprost inhibits the reaction [LHB protein results in increased secretion of Progesterone] | decreases reaction|increases secretion | 17760987 |
D011374 | Progesterone | EDN1 protein inhibits the reaction [LHB protein results in increased abundance of Progesterone] | decreases reaction|increases abundance | 15537863 |
D011374 | Progesterone | IGF1 protein inhibits the reaction [LHB protein results in increased abundance of Progesterone] | decreases reaction|increases abundance | 17154301 |
D011374 | Progesterone | LHB protein results in increased abundance of Progesterone | increases abundance | 17154301 16740971 |
D011374 | Progesterone | LHB protein results in increased secretion of Progesterone | increases secretion | 17760987 16303614 |
D011374 | Progesterone | PRKCE protein promotes the reaction [Dinoprost inhibits the reaction [LHB protein results in increased secretion of Progesterone]] | decreases reaction|increases reaction|increases secretion | 17760987 |
D011374 | Progesterone | Protein Kinase Inhibitors inhibits the reaction [Dinoprost inhibits the reaction [LHB protein results in increased abundance of Progesterone]] | decreases reaction|increases abundance | 15601909 |
D011374 | Progesterone | LHB protein results in increased secretion of Progesterone | increases secretion | 15525572 15967414 |
D011374 | Progesterone | N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [LHB protein results in increased secretion of Progesterone] | decreases reaction|increases secretion | 15967414 |
D011374 | Progesterone | LHB protein results in increased secretion of Progesterone | increases secretion | 17379658 17991618 |
D011374 | Progesterone | Atrazine inhibits the reaction [[estradiol 3-benzoate co-treated with Progesterone] results in increased secretion of LHB protein] | affects cotreatment|decreases reaction|increases secretion | 15056801 |
D011374 | Progesterone | [Estradiol co-treated with Progesterone] results in increased expression of LHB protein | affects cotreatment|increases expression | 17640482 |
D011374 | Progesterone | nociceptin (1-13) amide inhibits the reaction [PNOC protein inhibits the reaction [[Estradiol co-treated with Progesterone] results in increased expression of LHB protein]] | affects cotreatment|decreases reaction|increases expression | 17640482 |
D011374 | Progesterone | PNOC protein inhibits the reaction [[Estradiol co-treated with Progesterone] results in increased expression of LHB protein] | affects cotreatment|decreases reaction|increases expression | 17640482 |
D015237 | Dinoprost | 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Dinoprost inhibits the reaction [LHB protein results in increased secretion of Progesterone]] | decreases reaction|increases secretion | 17760987 |
D015237 | Dinoprost | Dinoprost inhibits the reaction [LHB protein results in increased abundance of Progesterone] | decreases reaction|increases abundance | 15601909 |
D015237 | Dinoprost | Dinoprost inhibits the reaction [LHB protein results in increased secretion of Progesterone] | decreases reaction|increases secretion | 17760987 |
D015237 | Dinoprost | PRKCE protein promotes the reaction [Dinoprost inhibits the reaction [LHB protein results in increased secretion of Progesterone]] | decreases reaction|increases reaction|increases secretion | 17760987 |
D015237 | Dinoprost | Protein Kinase Inhibitors inhibits the reaction [Dinoprost inhibits the reaction [LHB protein results in increased abundance of Progesterone]] | decreases reaction|increases abundance | 15601909 |
D011458 | Prostaglandins E | LHB protein results in increased secretion of Prostaglandins E | increases secretion | 17991618 |
D047428 | Protein Kinase Inhibitors | Protein Kinase Inhibitors inhibits the reaction [Dinoprost inhibits the reaction [LHB protein results in increased abundance of Progesterone]] | decreases reaction|increases abundance | 15601909 |
D020849 | Raloxifene | Raloxifene inhibits the reaction [estradiol 3-benzoate results in increased secretion of LHB protein] | decreases reaction|increases secretion | 17398000 |
D019821 | Simvastatin | Simvastatin promotes the reaction [[Ethinyl Estradiol co-treated with Desogestrel] results in decreased expression of LHB protein] | affects cotreatment|decreases expression|increases reaction | 17105841 |
D019821 | Simvastatin | Simvastatin promotes the reaction [ethinyl estradiol-desogestrel combination results in decreased expression of LHB protein] | decreases expression|increases reaction | 17105841 |
C484919 | SPP301 | SPP301 affects the reaction [[Ethinyl Estradiol co-treated with Levonorgestrel] affects the expression of LHB protein] | affects cotreatment|affects expression|affects reaction | 17190377 |
C484919 | SPP301 | SPP301 results in increased expression of LHB protein | increases expression | 17190377 |
D013629 | Tamoxifen | Tamoxifen results in decreased expression of LHB mRNA | decreases expression | 20647052 |
D013629 | Tamoxifen | Tamoxifen results in decreased expression of LHB mRNA | decreases expression | 19152838 |
D013629 | Tamoxifen | Tamoxifen results in increased expression of LHB mRNA | increases expression | 16330033 |
D043343 | Testosterone Propionate | Flutamide inhibits the reaction [Testosterone Propionate results in decreased expression of LHB protein] | decreases expression|decreases reaction | 11376863 |
D043343 | Testosterone Propionate | Testosterone Propionate results in decreased expression of LHB protein | decreases expression | 11376863 |
D013749 | Tetrachlorodibenzodioxin | estradiol 17 beta-cypionate promotes the reaction [[Tetrachlorodibenzodioxin co-treated with Gonadotropins, Equine] results in increased expression of LHB protein] | affects cotreatment|increases expression|increases reaction | 12606454 |
D013749 | Tetrachlorodibenzodioxin | estradiol 17 beta-cypionate promotes the reaction [[Tetrachlorodibenzodioxin co-treated with Gonadotropins, Equine] results in increased secretion of LHB protein] | affects cotreatment|increases reaction|increases secretion | 12606454 |
D013749 | Tetrachlorodibenzodioxin | Mifepristone promotes the reaction [[Tetrachlorodibenzodioxin co-treated with Gonadotropins, Equine] results in increased expression of LHB protein] | affects cotreatment|increases expression|increases reaction | 12606454 |
D013749 | Tetrachlorodibenzodioxin | Pentobarbital inhibits the reaction [[Tetrachlorodibenzodioxin co-treated with Gonadotropins, Equine] results in increased expression of LHB protein] | affects cotreatment|decreases reaction|increases expression | 12606454 |
D013749 | Tetrachlorodibenzodioxin | [Tetrachlorodibenzodioxin co-treated with Gonadotropins, Equine] results in increased expression of LHB protein | affects cotreatment|increases expression | 12606454 |
D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in decreased expression of [FSHB protein results in increased expression of LHB mRNA] | decreases expression|increases expression | 15746889 |
D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in decreased expression of [IGF1 protein results in increased stability of LHB mRNA] | decreases expression|increases stability | 15746889 |
D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in decreased expression of LHB mRNA | decreases expression | 19490992 19276399 16254025 |
D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in decreased expression of LHB protein | decreases expression | 16254025 |
D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in increased expression of LHB protein | increases expression | 16141434 |
D014260 | Triclosan | Triclosan results in decreased expression of LHB protein | decreases expression | 19118620 |
D014425 | Turpentine | Turpentine results in decreased expression of LHB protein | decreases expression | 12207160 |
C101044 | tyrphostin AG 1478 | tyrphostin AG 1478 inhibits the reaction [LHB protein results in increased expression of HAS2 mRNA] | decreases reaction|increases expression | 15459120 |
C101044 | tyrphostin AG 1478 | tyrphostin AG 1478 inhibits the reaction [LHB protein results in increased expression of PTGS2 mRNA] | decreases reaction|increases expression | 15459120 |
C101044 | tyrphostin AG 1478 | tyrphostin AG 1478 inhibits the reaction [LHB protein results in increased expression of TNFAIP6 mRNA] | decreases reaction|increases expression | 15459120 |
C101044 | tyrphostin AG 1478 | tyrphostin AG 1478 inhibits the reaction [LHB protein results in increased phosphorylation of EGFR protein] | decreases reaction|increases phosphorylation | 15459120 |
C025643 | vinclozolin | [vinclozolin co-treated with procymidone] results in increased expression of LHB protein | affects cotreatment|increases expression | 12563111 |
C025643 | vinclozolin | vinclozolin results in increased expression of LHB mRNA | increases expression | 14967917 17980475 |
C025643 | vinclozolin | vinclozolin results in increased expression of LHB protein | increases expression | 12563111 17980475 14967917 |
D014810 | Vitamin E | Vitamin E inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of LHB protein] | decreases expression|decreases reaction | 17280759 16298753 |
Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
---|---|---|---|---|---|
MESH:D000008 | Abdominal Neoplasms | Tamoxifen | 3.78 | 14745880 | |
MESH:D000014 | Abnormalities, Drug-Induced | Diethylhexyl Phthalate | 14.38 | 6734493 | |
MESH:D000014 | Abnormalities, Drug-Induced | Ethanol | 14.38 | 18926900 17676605 | |
MESH:D000014 | Abnormalities, Drug-Induced | methoxyacetic acid | 14.38 | 15959878 12805644 1761404 3652986 1761407 | |
MESH:D000014 | Abnormalities, Drug-Induced | Tetrachlorodibenzodioxin | 14.38 | 14514962 15322242 11752688 | |
MESH:D000022 | Abortion, Spontaneous | bromodichloromethane | 6.12 | 14691210 12970577 | |
MESH:D000138 | Acidosis | Ammonium Chloride | 7.98 | 18287403 | |
MESH:D000138 | Acidosis | Ethanol | 7.98 | 11192467 | |
MESH:D000152 | Acne Vulgaris | Ethinyl Estradiol | 3.18 | 17505938 | |
MESH:D055371 | Acute Lung Injury | Lipopolysaccharides | 7.27 | 11850527 18653653 | |
MESH:D055371 | Acute Lung Injury | Nickel | 7.27 | 16166738 | |
MESH:D000210 | Acute-Phase Reaction | Turpentine | 5.42 | 16044259 | |
MESH:D000230 | Adenocarcinoma | arsenic trioxide | 5.48 | 19825857 11798837 | |
MESH:D000230 | Adenocarcinoma | Estradiol | 5.48 | 11473722 | |
MESH:D000230 | Adenocarcinoma | Ethinyl Estradiol | 5.48 | 14692618 | |
MESH:D000236 | Adenoma | 4,4'-diaminodiphenylmethane | 2.28 | 3712494 | |
MESH:D018248 | Adenoma, Liver Cell | 3,4,5,3',4'-pentachlorobiphenyl | 8.06 | 16628245 | |
MESH:D018248 | Adenoma, Liver Cell | Tetrachlorodibenzodioxin | 8.06 | 16835633 | |
MESH:D000382 | Agricultural Workers' Diseases | Atrazine | 3.50 | 11874814 | |
MESH:D000419 | Albuminuria | Raloxifene | 3.88 | 17308373 17451421 | |
MESH:D020268 | Alcohol-Induced Disorders, Nervous System | Ethanol | 4.55 | 15451039 15451040 | |
MESH:D000505 | Alopecia | astressin B | 5.27 | 21359208 | |
MESH:D000544 | Alzheimer Disease | Copper | 3.87 | 16325427 16410023 17119284 16962711 16886094 16866297 | |
MESH:D000544 | Alzheimer Disease | Raloxifene | 3.87 | 15800139 | |
MESH:D000686 | Amyloidosis | Diethylstilbestrol | 3.76 | 15469931 | |
MESH:D000690 | Amyotrophic Lateral Sclerosis | Copper | 3.78 | 10694572 | |
MESH:D000740 | Anemia | Tetrachlorodibenzodioxin | 2.29 | 11748828 | |
MESH:D018798 | Anemia, Iron-Deficiency | Copper | 4.21 | 16614410 | |
MESH:D000799 | Angioedema | Acetaminophen | 3.08 | 10982225 | |
MESH:D000853 | Anophthalmos | Ethanol | 4.08 | 15513904 | |
MESH:D001008 | Anxiety Disorders | Ethanol | 11.45 | 11141031 | |
MESH:D001008 | Anxiety Disorders | Pentobarbital | 11.45 | 11141031 18313124 | |
MESH:D001008 | Anxiety Disorders | vinclozolin | 11.45 | 19015723 | |
MESH:D001161 | Arteriosclerosis | Ethinyl Estradiol | 2.73 | 11256880 | |
MESH:D001169 | Arthritis, Experimental | Dexamethasone | 5.66 | 17659584 | |
MESH:D001169 | Arthritis, Experimental | Ethinyl Estradiol | 5.66 | 15885639 | |
MESH:D001321 | Autistic Disorder | Acetaminophen | 1.55 | 18445737 | |
MESH:D053713 | Azoospermia | ABVD protocol | 10.56 | 17965791 | |
MESH:D053713 | Azoospermia | MOPP protocol | 10.56 | 17965791 | |
MESH:D001649 | Bile Duct Diseases | bromodichloromethane | 6.46 | 8717228 | |
MESH:D001660 | Biliary Tract Diseases | 4,4'-diaminodiphenylmethane | 4.25 | 11289319 1440618 | |
MESH:D001778 | Blood Coagulation Disorders | arsenic trioxide | 11.50 | 16206674 | |
MESH:D001778 | Blood Coagulation Disorders | Clofibrate | 11.50 | 19483382 | |
MESH:D001778 | Blood Coagulation Disorders | Tetrachlorodibenzodioxin | 11.50 | 12125929 | |
MESH:D001836 | Body Weight Changes | Tetrachlorodibenzodioxin | 3.03 | 15340226 | |
MESH:D001848 | Bone Diseases, Developmental | Tetrachlorodibenzodioxin | 2.24 | 15746008 | |
MESH:D001862 | Bone Resorption | bisphenol A | 3.19 | 11985600 | |
MESH:D020201 | Brain Hemorrhage, Traumatic | Progesterone | 4.57 | 17868700 | |
MESH:D001930 | Brain Injuries | Progesterone | 8.53 | 15665606 15380490 15845082 | |
MESH:D001930 | Brain Injuries | Raloxifene | 8.53 | 16580743 | |
MESH:D001932 | Brain Neoplasms | Copper | 3.90 | 17079463 | |
MESH:D001943 | Breast Neoplasms | Ascorbic Acid | 6.73 | 16443354 | |
MESH:D001943 | Breast Neoplasms | bisphenol A | 6.73 | 17123778 | |
MESH:D001943 | Breast Neoplasms | Copper | 6.73 | 15986119 17079463 | |
MESH:D001943 | Breast Neoplasms | Diethylstilbestrol | 6.73 | 17129689 15324884 | |
MESH:D001943 | Breast Neoplasms | Estradiol | 6.73 | 12948864 18497071 17289903 17018787 14630087 19861407 17261762 16675129 | |
MESH:D001943 | Breast Neoplasms | letrozole | 6.73 | 16002280 17892469 | |
MESH:D001943 | Breast Neoplasms | Nickel | 6.73 | 15986119 | |
MESH:D001943 | Breast Neoplasms | Progesterone | 6.73 | 15562024 16175315 17614352 | |
MESH:D001943 | Breast Neoplasms | Raloxifene | 6.73 | 16912660 17893378 17049068 15758505 17242785 15572757 17440819 16837676 17952589 15775269 17595753 17261762 | |
MESH:D001943 | Breast Neoplasms | Tamoxifen | 6.73 | 21138602 19155303 16873071 19142967 20859285 18351453 19487384 11161223 17440819 19084267 15565566 19115204 16273361 17242785 19410462 18855134 19288272 20135344 19103187 19189212 19289846 19221464 17261762 19011961 21152245 19189210 19200415 20544844 15668708 20065188 17049068 18815881 20390343 18629630 19244106 16202921 18425577 17893378 19059307 20005174 18821012 19066611 18984771 16818667 18997820 | |
MESH:D001943 | Breast Neoplasms | Tetrachlorodibenzodioxin | 6.73 | 20435547 | |
MESH:D016535 | Bronchial Hyperreactivity | tyrphostin AG 1478 | 4.28 | 12794006 | |
MESH:D002051 | Burkitt Lymphoma | arsenic trioxide | 3.63 | 11589617 | |
MESH:D002056 | Burns | Ethanol | 3.92 | 16374292 | |
MESH:D002181 | Candidiasis, Vulvovaginal | Estradiol | 3.71 | 16111702 | |
MESH:D002252 | Carbon Tetrachloride Poisoning | Vitamin E | 3.20 | 16050911 | |
MESH:D002277 | Carcinoma | Tetrachlorodibenzodioxin | 2.19 | 16835633 | |
MESH:D018270 | Carcinoma, Ductal, Breast | Tamoxifen | 3.77 | 19066611 | |
MESH:D006528 | Carcinoma, Hepatocellular | 4,4'-diaminodiphenylmethane | 11.20 | 3581430 7296757 | |
MESH:D006528 | Carcinoma, Hepatocellular | Acetaminophen | 11.20 | 3084413 | |
MESH:D006528 | Carcinoma, Hepatocellular | arsenic trioxide | 11.20 | 15073043 16217749 11135700 14691202 15553829 | |
MESH:D006528 | Carcinoma, Hepatocellular | Diethylstilbestrol | 11.20 | 15948411 16924424 | |
MESH:D006528 | Carcinoma, Hepatocellular | Estradiol | 11.20 | 16924424 | |
MESH:D006528 | Carcinoma, Hepatocellular | Ethanol | 11.20 | 15289165 15763234 18788625 | |
MESH:D006528 | Carcinoma, Hepatocellular | Tamoxifen | 11.20 | 16924424 | |
MESH:D002278 | Carcinoma in Situ | bisphenol A | 4.23 | 17123778 | |
MESH:D002291 | Carcinoma, Papillary | arsenic trioxide | 4.11 | 19014326 | |
MESH:D002292 | Carcinoma, Renal Cell | 4,4'-diaminodiphenylmethane | 2.27 | 7296757 | |
MESH:D018288 | Carcinoma, Small Cell | arsenic trioxide | 3.45 | 12490120 | |
MESH:D002295 | Carcinoma, Transitional Cell | Raloxifene | 7.30 | 17572228 | |
MESH:D002295 | Carcinoma, Transitional Cell | Tamoxifen | 7.30 | 17572228 | |
MESH:D006332 | Cardiomegaly | Copper | 8.79 | 17327471 | |
MESH:D006332 | Cardiomegaly | Ethanol | 8.79 | 19332462 | |
MESH:D006332 | Cardiomegaly | Tetrachlorodibenzodioxin | 8.79 | 16120746 18670907 18850075 | |
MESH:D002318 | Cardiovascular Diseases | Raloxifene | 2.90 | 15775269 | |
MESH:D002386 | Cataract | Acetaminophen | 6.14 | 10977129 | |
MESH:D002386 | Cataract | Simvastatin | 6.14 | 12518039 | |
MESH:D002471 | Cell Transformation, Neoplastic | 4,4'-diaminodiphenylmethane | 11.61 | 7505956 | |
MESH:D002471 | Cell Transformation, Neoplastic | Clofibrate | 11.61 | 1399818 | |
MESH:D002471 | Cell Transformation, Neoplastic | Dinoprost | 11.61 | 16192471 | |
MESH:D002471 | Cell Transformation, Neoplastic | Estradiol | 11.61 | 18566989 | |
MESH:D014355 | Chagas Disease | Nitrofurazone | 6.41 | 11354658 | |
MESH:D018281 | Cholangiocarcinoma | 3,4,5,3',4'-pentachlorobiphenyl | 7.66 | 16628245 | |
MESH:D018281 | Cholangiocarcinoma | Tetrachlorodibenzodioxin | 7.66 | 16835633 | |
MESH:D002779 | Cholestasis | 4,4'-diaminodiphenylmethane | 10.27 | 19486331 9022650 | |
MESH:D002779 | Cholestasis | Ethinyl Estradiol | 10.27 | 17681005 15861022 17110522 16105132 17333356 16919318 11677210 | |
MESH:D002779 | Cholestasis | Levonorgestrel | 10.27 | 15861022 | |
MESH:D002971 | Cleft Lip | Ethanol | 3.13 | 15513904 | |
MESH:D002972 | Cleft Palate | Ethanol | 4.67 | 15513904 | |
MESH:D002972 | Cleft Palate | Tetrachlorodibenzodioxin | 4.67 | 12621046 15340226 16354765 8697196 15668235 | |
MESH:D003072 | Cognition Disorders | Raloxifene | 3.88 | 15800139 | |
MESH:D003110 | Colonic Neoplasms | bromodichloromethane | 3.96 | 14668109 | |
MESH:D003110 | Colonic Neoplasms | Dexamethasone | 3.96 | 15824018 | |
MESH:D015179 | Colorectal Neoplasms | arsenic trioxide | 1.86 | 20501625 | |
MESH:D003139 | Common Cold | Ascorbic Acid | 4.71 | 17323712 | |
MESH:D000013 | Congenital Abnormalities | Tetrachlorodibenzodioxin | 7.40 | 14669216 17141729 | |
MESH:D000013 | Congenital Abnormalities | Triclosan | 7.40 | 19283420 | |
MESH:D023903 | Coronary Restenosis | arsenic trioxide | 3.47 | 12609071 | |
MESH:D019465 | Craniofacial Abnormalities | 3,4,5,3',4'-pentachlorobiphenyl | 7.71 | 17686920 | |
MESH:D019465 | Craniofacial Abnormalities | arsenic trioxide | 7.71 | 10525206 | |
MESH:D019465 | Craniofacial Abnormalities | Dexamethasone | 7.71 | 17728286 | |
MESH:D019465 | Craniofacial Abnormalities | Ethanol | 7.71 | 15513904 15451039 11873399 19302082 15451040 11198716 10194807 | |
MESH:D019465 | Craniofacial Abnormalities | Tetrachlorodibenzodioxin | 7.71 | 20055451 10048152 15322242 | |
MESH:D019465 | Craniofacial Abnormalities | Vitamin E | 7.71 | 19769572 | |
MESH:D003456 | Cryptorchidism | Diethylstilbestrol | 8.99 | 12952375 16002989 | |
MESH:D003456 | Cryptorchidism | vinclozolin | 8.99 | 14966744 | |
MESH:D003550 | Cystic Fibrosis | Simvastatin | 4.29 | 19747007 | |
MESH:D016757 | Death, Sudden, Cardiac | arsenic trioxide | 3.40 | 15213294 | |
MESH:D003711 | Demyelinating Diseases | Tamoxifen | 3.63 | 19031437 | |
MESH:D003865 | Depressive Disorder, Major | Raloxifene | 3.51 | 17474826 | |
MESH:D017449 | Dermatitis, Allergic Contact | 4,4'-diaminodiphenylmethane | 7.58 | 18759878 8970840 8156756 11298694 12868966 14531868 2524372 11906362 | |
MESH:D017449 | Dermatitis, Allergic Contact | Dexamethasone | 7.58 | 12438553 | |
MESH:D017449 | Dermatitis, Allergic Contact | Nickel | 7.58 | 17100760 19470301 17244072 | |
MESH:D003876 | Dermatitis, Atopic | Diethylhexyl Phthalate | 3.64 | 16882537 | |
MESH:D003877 | Dermatitis, Contact | 4,4'-diaminodiphenylmethane | 7.23 | 3621924 2952479 | |
MESH:D003877 | Dermatitis, Contact | Nickel | 7.23 | 2952479 | |
MESH:D003924 | Diabetes Mellitus, Type 2 | Ascorbic Acid | 3.70 | 16506275 | |
MESH:D003924 | Diabetes Mellitus, Type 2 | Tetrachlorodibenzodioxin | 3.70 | 17107852 | |
MESH:D003928 | Diabetic Nephropathies | Estradiol | 11.29 | 19279558 | |
MESH:D003928 | Diabetic Nephropathies | Raloxifene | 11.29 | 17451421 15920148 17308373 | |
MESH:D003928 | Diabetic Nephropathies | Tamoxifen | 11.29 | 19279558 | |
MESH:D003929 | Diabetic Neuropathies | Progesterone | 3.76 | 17187935 | |
MESH:D003967 | Diarrhea | Dexamethasone | 3.01 | 7237001 | |
MESH:D012734 | Disorders of Sex Development | marker/mechanism | |||
MESH:D056486 | Drug-Induced Liver Injury | 4,4'-diaminodiphenylmethane | 8.81 | 18692083 18289764 6679447 7440962 9328219 6482804 11289319 9022650 18648102 9653073 8291058 16192314 1440618 | |
MESH:D056486 | Drug-Induced Liver Injury | Acetaminophen | 8.81 | 2444490 16781746 19416960 16109766 12153990 14725611 11461765 16177239 12540782 19085960 18071297 12705907 14550746 14986274 11743745 16081117 17562736 17906064 18713872 19739265 10774834 11287661 16485898 17522070 12594235 11834606 10663392 11421492 19923254 12958197 16393943 16227642 19164858 15968718 11739529 15619225 11529661 10915739 19370779 19420014 12392966 | |
MESH:D056486 | Drug-Induced Liver Injury | Chlorodiphenyl (54% Chlorine) | 8.81 | 17851650 | |
MESH:D056486 | Drug-Induced Liver Injury | Ethanol | 8.81 | 11566570 | |
MESH:D056486 | Drug-Induced Liver Injury | Tetrachlorodibenzodioxin | 8.81 | 20420201 | |
MESH:D056487 | Drug-Induced Liver Injury, Chronic | Acetaminophen | 3.33 | 19426721 | |
MESH:D004362 | Drug Toxicity | Tetrachlorodibenzodioxin | 2.18 | 11462148 | |
MESH:D050171 | Dyslipidemias | Clofibrate | 3.49 | 16707586 | |
MESH:C538011 | Eales disease | Ascorbic Acid | 10.53 | 9068938 | |
MESH:C538011 | Eales disease | Vitamin E | 10.53 | 9068938 | |
MESH:D004485 | Eczema | Dexamethasone | 3.74 | 12438553 | |
MESH:D004487 | Edema | Dexamethasone | 7.70 | 19703484 | |
MESH:D004487 | Edema | Raloxifene | 7.70 | 15860553 | |
MESH:D004487 | Edema | Tetrachlorodibenzodioxin | 7.70 | 12711302 11000095 | |
MESH:D004489 | Edema, Cardiac | 3,4,5,3',4'-pentachlorobiphenyl | 9.88 | 17686920 | |
MESH:D004489 | Edema, Cardiac | Tetrachlorodibenzodioxin | 9.88 | 15322242 16714409 18230668 | |
MESH:D004681 | Encephalomyelitis, Autoimmune, Experimental | Ethinyl Estradiol | 16.09 | 12538720 | |
MESH:D004681 | Encephalomyelitis, Autoimmune, Experimental | Progesterone | 16.09 | 17692515 | |
MESH:D004681 | Encephalomyelitis, Autoimmune, Experimental | Raloxifene | 16.09 | 15845917 | |
MESH:D004681 | Encephalomyelitis, Autoimmune, Experimental | Tamoxifen | 16.09 | 19031437 | |
MESH:D004714 | Endometrial Hyperplasia | Diethylstilbestrol | 3.94 | 16402032 | |
MESH:D016889 | Endometrial Neoplasms | Diethylstilbestrol | 9.37 | 16804899 15700306 | |
MESH:D016889 | Endometrial Neoplasms | Estradiol | 9.37 | 19148513 11473722 18566989 | |
MESH:D016889 | Endometrial Neoplasms | Tamoxifen | 9.37 | 20544844 16202921 17893378 19155303 | |
MESH:D004715 | Endometriosis | Mifepristone | 11.50 | 16134523 | |
MESH:D004715 | Endometriosis | Progesterone | 11.50 | 16134523 | |
MESH:D004715 | Endometriosis | Tetrachlorodibenzodioxin | 11.50 | 10568697 9294722 | |
MESH:D019446 | Endotoxemia | Lipopolysaccharides | 3.65 | 17637181 15328337 15821434 | |
MESH:D007172 | Erectile Dysfunction | estradiol valerate | 5.10 | 14972507 | |
MESH:D004938 | Esophageal Neoplasms | 4,4'-diaminodiphenylmethane | 5.73 | 3581430 | |
MESH:D004938 | Esophageal Neoplasms | arsenic trioxide | 5.73 | 12903497 | |
MESH:D004938 | Esophageal Neoplasms | Ethanol | 5.73 | 16704527 | |
MESH:D005124 | Eye Abnormalities | Tetrachlorodibenzodioxin | 2.42 | 11564622 | |
MESH:D005234 | Fatty Liver | arsenic trioxide | 22.02 | 15073043 | |
MESH:D005234 | Fatty Liver | Clofibrate | 22.02 | 19224547 | |
MESH:D005234 | Fatty Liver | Ethanol | 22.02 | 18620774 19236843 16409862 | |
MESH:D005234 | Fatty Liver | Ethinyl Estradiol | 22.02 | 15345470 | |
MESH:D005234 | Fatty Liver | Raloxifene | 22.02 | 17473493 | |
MESH:D005234 | Fatty Liver | Tamoxifen | 22.02 | 19224547 14986274 | |
MESH:D005235 | Fatty Liver, Alcoholic | Ethanol | 4.90 | 17920746 | |
MESH:D052776 | Female Urogenital Diseases | Diethylstilbestrol | 6.51 | 16611131 15751030 16513791 16002989 16534752 | |
MESH:D052776 | Female Urogenital Diseases | Tamoxifen | 6.51 | 16709447 | |
MESH:D005310 | Fetal Alcohol Syndrome | Ethanol | 4.55 | 16946407 15513904 10194807 15451040 | |
MESH:D005313 | Fetal Death | Tetrachlorodibenzodioxin | 2.72 | 11858732 | |
MESH:D005334 | Fever | Dinoprost | 7.67 | 11852909 | |
MESH:D005334 | Fever | Lipopolysaccharides | 7.67 | 11852909 9205823 | |
MESH:D005350 | Fibroma | 4,4'-diaminodiphenylmethane | 4.25 | 6705139 | |
MESH:D018221 | Fibromatosis, Abdominal | Tamoxifen | 3.77 | 14745880 | |
MESH:D018222 | Fibromatosis, Aggressive | Tamoxifen | 3.43 | 19069698 | |
MESH:D005355 | Fibrosis | Tetrachlorodibenzodioxin | 2.23 | 20067830 | |
MESH:D005532 | Foot Deformities, Congenital | methoxyacetic acid | 5.00 | 3652986 | |
MESH:D005706 | Gallbladder Neoplasms | arsenic trioxide | 3.54 | 16904648 | |
MESH:D005756 | Gastritis | Acetaminophen | 8.59 | 16983495 | |
MESH:D005756 | Gastritis | Ethanol | 8.59 | 15046732 | |
MESH:D030342 | Genetic Diseases, Inborn | vinclozolin | 4.18 | 16973722 | |
MESH:D005832 | Genital Diseases, Male | vinclozolin | 4.53 | 16417039 | |
MESH:D005833 | Genital Neoplasms, Female | Diethylstilbestrol | 4.19 | 16452187 | |
MESH:D006042 | Goiter | 4,4'-diaminodiphenylmethane | 3.34 | 7505956 | |
MESH:D006058 | Gonadal Disorders | Tetrachlorodibenzodioxin | 3.83 | 10696789 | |
MESH:D006330 | Heart Defects, Congenital | 3,4,3',4'-tetrachlorobiphenyl | 16.25 | 11294989 | |
MESH:D006330 | Heart Defects, Congenital | 3,4,5,3',4'-pentachlorobiphenyl | 16.25 | 17686920 20471113 | |
MESH:D006330 | Heart Defects, Congenital | Ascorbic Acid | 16.25 | 16080930 | |
MESH:D006330 | Heart Defects, Congenital | Tetrachlorodibenzodioxin | 16.25 | 10048152 11294989 | |
MESH:D006330 | Heart Defects, Congenital | Vitamin E | 16.25 | 16080930 | |
MESH:D006331 | Heart Diseases | Raloxifene | 2.99 | 11110106 | |
MESH:D006463 | Hemolytic-Uremic Syndrome | Lipopolysaccharides | 3.72 | 16366002 | |
MESH:D006470 | Hemorrhage | Tetrachlorodibenzodioxin | 2.65 | 11000095 | |
MESH:D006505 | Hepatitis | 4,4'-diaminodiphenylmethane | 2.80 | 6705139 | |
MESH:D006521 | Hepatitis, Chronic | Copper | 4.51 | 17338147 | |
MESH:D006527 | Hepatolenticular Degeneration | Copper | 4.43 | 16607473 17276780 19888908 17182432 17109627 | |
MESH:D006529 | Hepatomegaly | Tetrachlorodibenzodioxin | 2.18 | 15340226 12621046 16120746 | |
MESH:D006548 | Hernia, Diaphragmatic | Ascorbic Acid | 7.71 | 16490937 16863852 | |
MESH:D006548 | Hernia, Diaphragmatic | Dexamethasone | 7.71 | 7520565 | |
MESH:D006548 | Hernia, Diaphragmatic | Vitamin E | 7.71 | 16863852 16490937 | |
MESH:D006558 | Herpes Genitalis | Estradiol | 4.26 | 15709030 | |
MESH:D006628 | Hirsutism | LHRH, Ala(6)-Gly(10)-ethylamide- | 6.60 | 11228061 | |
MESH:D015658 | HIV Infections | Nickel | 3.38 | 17263646 | |
MESH:D006689 | Hodgkin Disease | ABVD protocol | 6.95 | 17065142 15837968 10798542 16135485 12907440 16794504 17673811 15621842 17168361 16640815 15453925 17606976 14565654 14657226 17646666 15183480 15315964 15941081 17954296 17420510 17726078 17713864 12586796 14752856 16264800 18024389 14760121 18072259 18180244 12805333 16314615 17459049 17846017 15199092 18154127 15465201 17562619 18209012 16172458 17515571 16879607 12162096 17562247 17071938 17085663 | |
MESH:D006689 | Hodgkin Disease | MOPP protocol | 6.95 | 17726078 17981817 15183480 17562247 12805333 15170884 16966260 14760121 17515571 14752856 | |
MESH:D019584 | Hot Flashes | 8-prenylnaringenin | 12.90 | 17088409 | |
MESH:D019584 | Hot Flashes | Estradiol | 12.90 | 17088409 | |
MESH:D019584 | Hot Flashes | Vitamin E | 12.90 | 14716179 | |
MESH:D006869 | Hydronephrosis | Tetrachlorodibenzodioxin | 3.28 | 18606429 15340226 16354765 8697196 16959395 | |
MESH:D006930 | Hyperalgesia | Acetaminophen | 5.78 | 16870215 | |
MESH:D006930 | Hyperalgesia | Ethanol | 5.78 | 18783367 | |
MESH:D017588 | Hyperandrogenism | Flutamide | 4.70 | 15356085 | |
MESH:D006938 | Hyperlipoproteinemia Type II | Simvastatin | 4.60 | 16238680 | |
MESH:D006965 | Hyperplasia | 4,4'-diaminodiphenylmethane | 8.40 | 15034207 | |
MESH:D006965 | Hyperplasia | Diethylstilbestrol | 8.40 | 12960047 14722030 | |
MESH:D006973 | Hypertension | Dexamethasone | 6.59 | 17042910 | |
MESH:D006973 | Hypertension | Raloxifene | 6.59 | 15787275 17577099 | |
MESH:D006973 | Hypertension | Tetrachlorodibenzodioxin | 6.59 | 18670907 18850075 | |
MESH:D007006 | Hypogonadism | marker/mechanism | 18449926 | ||
MESH:D007021 | Hypospadias | Diethylstilbestrol | 8.80 | 16002989 | |
MESH:D007021 | Hypospadias | Ethinyl Estradiol | 8.80 | 16945680 16569931 | |
MESH:D007057 | Ichthyosis | ABVD protocol | 6.15 | 12162096 | |
MESH:D020244 | Infarction, Middle Cerebral Artery | Progesterone | 3.67 | 15869954 | |
MESH:D007246 | Infertility | marker/mechanism | |||
MESH:D007246 | Infertility | Diethylstilbestrol | 3.64 | 15036965 | |
MESH:D007247 | Infertility, Female | Ethinyl Estradiol | 2.76 | 12013081 | |
MESH:D007248 | Infertility, Male | Atrazine | 15.45 | 12948887 | |
MESH:D007248 | Infertility, Male | Ethinyl Estradiol | 15.45 | 17937319 | |
MESH:D007248 | Infertility, Male | MOPP protocol | 15.45 | 14752856 | |
MESH:D007248 | Infertility, Male | Triclosan | 15.45 | 20821571 | |
MESH:D007248 | Infertility, Male | vinclozolin | 15.45 | 16467254 | |
MESH:D007249 | Inflammation | Dexamethasone | 17.31 | 8960868 11099482 | |
MESH:D007249 | Inflammation | Lipopolysaccharides | 17.31 | 17963957 17237260 17255318 12878042 9205823 | |
MESH:D007249 | Inflammation | Nickel | 17.31 | 16166738 | |
MESH:D007249 | Inflammation | Progesterone | 17.31 | 15869954 | |
MESH:D007249 | Inflammation | Tamoxifen | 17.31 | 19457130 | |
MESH:D007249 | Inflammation | Tetrachlorodibenzodioxin | 17.31 | 12878042 12200463 | |
MESH:D007249 | Inflammation | Triclosan | 17.31 | 9584910 20507366 | |
MESH:D007251 | Influenza, Human | Vitamin E | 3.45 | 16624496 | |
MESH:D007333 | Insulin Resistance | bisphenol A | 5.66 | 16393666 | |
MESH:D007333 | Insulin Resistance | Estradiol | 5.66 | 16393666 16627594 | |
MESH:D019189 | Iron Metabolism Disorders | Lipopolysaccharides | 3.93 | 17255318 | |
MESH:D007565 | Jaundice | 4,4'-diaminodiphenylmethane | 4.25 | 9022650 8074119 | |
MESH:D007569 | Jaw Abnormalities | Ethanol | 7.85 | 15513904 | |
MESH:D007569 | Jaw Abnormalities | Tetrachlorodibenzodioxin | 7.85 | 16580747 | |
MESH:D007674 | Kidney Diseases | Acetaminophen | 7.22 | 15629191 12587719 | |
MESH:D007674 | Kidney Diseases | Estradiol | 7.22 | 15618244 | |
MESH:D007674 | Kidney Diseases | Vitamin E | 7.22 | 12488133 | |
MESH:D007676 | Kidney Failure, Chronic | Copper | 4.22 | 16518626 | |
MESH:D007680 | Kidney Neoplasms | 4,4'-diaminodiphenylmethane | 12.66 | 6582329 | |
MESH:D007680 | Kidney Neoplasms | Diethylstilbestrol | 12.66 | 15003126 16762066 14681315 | |
MESH:D007680 | Kidney Neoplasms | Estradiol | 12.66 | 15610895 | |
MESH:D007680 | Kidney Neoplasms | Tamoxifen | 12.66 | 18625569 | |
MESH:D007683 | Kidney Tubular Necrosis, Acute | Calcium | 4.28 | 16316344 | |
MESH:D007859 | Learning Disorders | Copper | 12.02 | 17134702 | |
MESH:D007859 | Learning Disorders | Diethylstilbestrol | 12.02 | 17184923 | |
MESH:D007859 | Learning Disorders | Ethanol | 12.02 | 15451040 | |
MESH:D007889 | Leiomyoma | Raloxifene | 3.80 | 16973256 | |
MESH:D007938 | Leukemia | arsenic trioxide | 2.41 | 15070760 | |
MESH:D015459 | Leukemia-Lymphoma, Adult T-Cell | arsenic trioxide | 3.12 | 12560223 17077332 | |
MESH:D007948 | Leukemia, Monocytic, Acute | arsenic trioxide | 3.56 | 16972261 | |
MESH:D015464 | Leukemia, Myelogenous, Chronic, BCR-ABL Positive | arsenic trioxide | 2.85 | 14633726 | |
MESH:D007951 | Leukemia, Myeloid | arsenic trioxide | 3.08 | 19077051 | |
MESH:D015470 | Leukemia, Myeloid, Acute | arsenic trioxide | 4.11 | 16467208 16968895 19850784 17050201 20471514 | |
MESH:D015470 | Leukemia, Myeloid, Acute | MOPP protocol | 4.11 | 12100147 | |
MESH:D015473 | Leukemia, Promyelocytic, Acute | arsenic trioxide | 2.68 | 17869043 16891316 19225113 17107899 17217047 17712046 16966277 16112521 15748426 19075265 16331271 16823087 15336539 9834237 11161223 11468182 12018890 15213294 15622746 19035177 12679006 17649720 16330433 19642359 12712474 | |
MESH:D015458 | Leukemia, T-Cell | arsenic trioxide | 3.63 | 16882451 | |
MESH:D007970 | Leukopenia | Lipopolysaccharides | 3.95 | 15821434 | |
MESH:D007984 | Leydig Cell Tumor | vinclozolin | 3.98 | 16417039 | |
MESH:D017880 | Limb Deformities, Congenital | Ethanol | 6.94 | 17676605 | |
MESH:D017880 | Limb Deformities, Congenital | methoxyacetic acid | 6.94 | 12805644 15959878 | |
MESH:D008064 | Lipidoses | Tamoxifen | 2.59 | 17567588 15342952 | |
MESH:D008103 | Liver Cirrhosis | Ethanol | 2.91 | 15289165 | |
MESH:D008104 | Liver Cirrhosis, Alcoholic | Ethanol | 4.34 | 18295389 | |
MESH:D008105 | Liver Cirrhosis, Biliary | 4,4'-diaminodiphenylmethane | 2.68 | 9327722 15034207 | |
MESH:D008106 | Liver Cirrhosis, Experimental | Dexamethasone | 8.63 | 16718785 | |
MESH:D008106 | Liver Cirrhosis, Experimental | Estradiol | 8.63 | 14716833 14659978 | |
MESH:D008106 | Liver Cirrhosis, Experimental | Ethanol | 8.63 | 18166357 | |
MESH:D008106 | Liver Cirrhosis, Experimental | Lipopolysaccharides | 8.63 | 12878042 | |
MESH:D008106 | Liver Cirrhosis, Experimental | Tamoxifen | 8.63 | 18564211 | |
MESH:D008106 | Liver Cirrhosis, Experimental | Tetrachlorodibenzodioxin | 8.63 | 12878042 | |
MESH:D008106 | Liver Cirrhosis, Experimental | Vitamin E | 8.63 | 16169303 | |
MESH:D008107 | Liver Diseases | Acetaminophen | 1.42 | 19784758 12587719 19014921 16611625 12969438 16610002 19460945 11587558 | |
MESH:D008108 | Liver Diseases, Alcoholic | Ethanol | 3.92 | 17207112 17347304 | |
MESH:D017114 | Liver Failure, Acute | Acetaminophen | 2.57 | 16871587 17185352 | |
MESH:D008113 | Liver Neoplasms | 2,4,5,2',4',5'-hexachlorobiphenyl | 16.36 | 18644402 16835634 | |
MESH:D008113 | Liver Neoplasms | arsenic trioxide | 16.36 | 14682389 | |
MESH:D008113 | Liver Neoplasms | Copper | 16.36 | 20302851 | |
MESH:D008113 | Liver Neoplasms | Diethylhexyl Phthalate | 16.36 | 11940454 | |
MESH:D008113 | Liver Neoplasms | Diethylstilbestrol | 16.36 | 15890375 16712894 | |
MESH:D008113 | Liver Neoplasms | Tamoxifen | 16.36 | 16684651 | |
MESH:D008113 | Liver Neoplasms | Tetrachlorodibenzodioxin | 16.36 | 16984957 | |
MESH:D008114 | Liver Neoplasms, Experimental | 4,4'-diaminodiphenylmethane | 9.92 | 598648 1399818 6587162 3712494 | |
MESH:D008114 | Liver Neoplasms, Experimental | arsenic trioxide | 9.92 | 20377131 | |
MESH:D008114 | Liver Neoplasms, Experimental | Ascorbic Acid | 9.92 | 18544905 | |
MESH:D008114 | Liver Neoplasms, Experimental | Tetrachlorodibenzodioxin | 9.92 | 12151625 | |
MESH:D008133 | Long QT Syndrome | arsenic trioxide | 2.76 | 15213294 | |
MESH:D008171 | Lung Diseases | Ascorbic Acid | 5.92 | 16863852 | |
MESH:D008171 | Lung Diseases | Vitamin E | 5.92 | 16863852 | |
MESH:D055370 | Lung Injury | Lipopolysaccharides | 3.29 | 21114838 | |
MESH:D008175 | Lung Neoplasms | arsenic trioxide | 6.68 | 19825857 11798837 | |
MESH:D008175 | Lung Neoplasms | Ascorbic Acid | 6.68 | 16401635 | |
MESH:D008175 | Lung Neoplasms | Dexamethasone | 6.68 | 11195469 15824018 | |
MESH:D008175 | Lung Neoplasms | Tamoxifen | 6.68 | 18625569 | |
MESH:D008175 | Lung Neoplasms | Tetrachlorodibenzodioxin | 6.68 | 19555203 11884234 | |
MESH:D008175 | Lung Neoplasms | Vitamin E | 6.68 | 11062179 | |
MESH:D008181 | Lupus Nephritis | Diethylstilbestrol | 4.40 | 15166399 | |
MESH:D008223 | Lymphoma | Diethylstilbestrol | 2.91 | 15700306 | |
MESH:D016483 | Lymphoma, AIDS-Related | ABVD protocol | 6.15 | 12176798 17378895 17296568 | |
MESH:D052801 | Male Urogenital Diseases | Diethylstilbestrol | 4.75 | 16002989 | |
MESH:D015674 | Mammary Neoplasms, Animal | Tamoxifen | 3.02 | 19428831 | |
MESH:D008325 | Mammary Neoplasms, Experimental | Estradiol | 13.30 | 11408345 17203775 16891317 11807958 | |
MESH:D008325 | Mammary Neoplasms, Experimental | estradiol 3-benzoate | 13.30 | 15375486 | |
MESH:D008325 | Mammary Neoplasms, Experimental | Progesterone | 13.30 | 17203775 11408345 | |
MESH:D008325 | Mammary Neoplasms, Experimental | Tamoxifen | 13.30 | 19196723 19196722 16827153 11731420 14580682 | |
MESH:D008325 | Mammary Neoplasms, Experimental | Triclosan | 13.30 | 15358634 | |
MESH:D020149 | Manganese Poisoning | Estradiol | 10.10 | 19453300 | |
MESH:D020149 | Manganese Poisoning | Tamoxifen | 10.10 | 19453300 | |
MESH:D008545 | Melanoma | Tamoxifen | 1.77 | 19393235 12393984 | |
MESH:D018328 | Melanoma, Amelanotic | Tamoxifen | 3.43 | 15990972 | |
MESH:D008546 | Melanoma, Experimental | Acetaminophen | 2.83 | 19513568 | |
MESH:D008569 | Memory Disorders | Ethanol | 3.48 | 18411066 15451040 | |
MESH:D007706 | Menkes Kinky Hair Syndrome | Copper | 5.13 | 17268249 17109627 | |
MESH:D008654 | Mesothelioma | Atrazine | 3.17 | 1916698 | |
MESH:D018200 | Mixed Tumor, Mullerian | Raloxifene | 4.79 | 15863610 | |
MESH:D009101 | Multiple Myeloma | arsenic trioxide | 8.90 | 15949261 19417148 14977855 19549372 11468182 | |
MESH:D009101 | Multiple Myeloma | Dexamethasone | 8.90 | 15744524 15867202 16118317 | |
MESH:D009101 | Multiple Myeloma | Raloxifene | 8.90 | 16497877 | |
MESH:D009182 | Mycosis Fungoides | arsenic trioxide | 3.91 | 18349030 | |
MESH:D009190 | Myelodysplastic Syndromes | arsenic trioxide | 5.94 | 16105982 16882451 | |
MESH:D009190 | Myelodysplastic Syndromes | Dexamethasone | 5.94 | 9809623 | |
MESH:D009203 | Myocardial Infarction | ABVD protocol | 4.55 | 17284715 | |
MESH:D017202 | Myocardial Ischemia | Tetrachlorodibenzodioxin | 2.40 | 12213967 | |
MESH:D015428 | Myocardial Reperfusion Injury | Estradiol | 2.68 | 16810080 | |
MESH:D009232 | Myxoma | Raloxifene | 4.79 | 16343187 | |
MESH:D009361 | Neoplasm Invasiveness | arsenic trioxide | 3.25 | 16624393 | |
MESH:D009362 | Neoplasm Metastasis | 4,4'-diaminodiphenylmethane | 4.45 | 3581430 | |
MESH:D009362 | Neoplasm Metastasis | Tamoxifen | 4.45 | 19393235 | |
MESH:D009364 | Neoplasm Recurrence, Local | Tamoxifen | 2.21 | 19410462 | |
MESH:D009369 | Neoplasms | 2,4,5,2',4',5'-hexachlorobiphenyl | 6.27 | 8820588 | |
MESH:D009369 | Neoplasms | Diethylstilbestrol | 6.27 | 15313581 | |
MESH:D009369 | Neoplasms | Nitrofurazone | 6.27 | 15488632 | |
MESH:D009376 | Neoplasms, Hormone-Dependent | Tamoxifen | 3.24 | 19196722 19189210 19200415 | |
MESH:D009389 | Neovascularization, Pathologic | Copper | 7.86 | 17308104 | |
MESH:D009389 | Neovascularization, Pathologic | Estradiol | 7.86 | 17289903 | |
MESH:D009402 | Nephrosis, Lipoid | ABVD protocol | 6.36 | 17954296 | |
MESH:D009421 | Nervous System Malformations | bisphenol A | 17.61 | 11399458 16427766 | |
MESH:D009421 | Nervous System Malformations | Diethylstilbestrol | 17.61 | 11399458 | |
MESH:D009421 | Nervous System Malformations | Estradiol | 17.61 | 16427766 11399458 | |
MESH:D009421 | Nervous System Malformations | Tetrachlorodibenzodioxin | 17.61 | 14600291 | |
MESH:D009436 | Neural Tube Defects | 4,4'-diaminodiphenylmethane | 5.47 | 6679447 | |
MESH:D009436 | Neural Tube Defects | arsenic trioxide | 5.47 | 10525206 | |
MESH:D019636 | Neurodegenerative Diseases | Acetaminophen | 2.25 | 18514411 | |
MESH:D009503 | Neutropenia | ABVD protocol | 5.23 | 17071938 16690524 | |
MESH:D052556 | Niemann-Pick Disease, Type C | Clofibrate | 4.20 | 9802331 | |
MESH:D009765 | Obesity | Ascorbic Acid | 2.91 | 17217161 | |
MESH:D009784 | Occupational Diseases | 4,4'-diaminodiphenylmethane | 2.76 | 4026338 6482804 | |
MESH:D009845 | Oligospermia | ABVD protocol | 9.69 | 17965791 | |
MESH:D009845 | Oligospermia | MOPP protocol | 9.69 | 17965791 | |
MESH:D009902 | Optic Neuritis | 4,4'-diaminodiphenylmethane | 4.25 | 3988306 | |
MESH:D010024 | Osteoporosis | Calcium | 9.22 | 17882678 | |
MESH:D010024 | Osteoporosis | Levonorgestrel | 9.22 | 12665316 | |
MESH:D010024 | Osteoporosis | Raloxifene | 9.22 | 15775268 17882678 19059307 | |
MESH:D015663 | Osteoporosis, Postmenopausal | Raloxifene | 3.53 | 17823083 15758505 17893378 15579764 | |
MESH:D010049 | Ovarian Diseases | bisphenol A | 4.23 | 11985600 | |
MESH:D010051 | Ovarian Neoplasms | arsenic trioxide | 11.66 | 19769630 16624393 12452020 | |
MESH:D010051 | Ovarian Neoplasms | Estradiol | 11.66 | 19401270 | |
MESH:D010051 | Ovarian Neoplasms | Mifepristone | 11.66 | 16525653 | |
MESH:D010051 | Ovarian Neoplasms | Nitrofurazone | 11.66 | 11026599 | |
MESH:D010051 | Ovarian Neoplasms | Progesterone | 11.66 | 16525653 17393432 | |
MESH:D010146 | Pain | Acetaminophen | 1.80 | 16870215 | |
MESH:D010190 | Pancreatic Neoplasms | arsenic trioxide | 4.34 | 15580305 | |
MESH:D010190 | Pancreatic Neoplasms | Ethanol | 4.34 | 12384795 | |
MESH:D010195 | Pancreatitis | Methomyl | 4.68 | 16258382 15767733 | |
MESH:D016584 | Panic Disorder | Ethinyl Estradiol | 2.99 | 11578682 | |
MESH:D010212 | Papilloma | 4,4'-diaminodiphenylmethane | 2.76 | 7296757 | |
MESH:D010235 | Paraganglioma | arsenic trioxide | 3.46 | 19927285 | |
MESH:D010300 | Parkinson Disease | Atrazine | 2.95 | 17218051 | |
MESH:D010382 | Peliosis Hepatis | Tetrachlorodibenzodioxin | 3.48 | 12520081 | |
MESH:D010787 | Photosensitivity Disorders | 4,4'-diaminodiphenylmethane | 3.70 | 6228378 | |
MESH:D010900 | Pituitary Diseases | Diethylstilbestrol | 4.40 | 14722030 | |
MESH:D010911 | Pituitary Neoplasms | Diethylstilbestrol | 3.93 | 15687265 16977796 | |
MESH:D011014 | Pneumonia | Lipopolysaccharides | 3.81 | 12224865 11605937 | |
MESH:D011041 | Poisoning | Methomyl | 4.75 | 11800311 | |
MESH:D011085 | Polycystic Ovary Syndrome | ethinyl estradiol-desogestrel combination | 13.31 | 17105841 | |
MESH:D011085 | Polycystic Ovary Syndrome | Flutamide | 13.31 | 15356085 | |
MESH:D011085 | Polycystic Ovary Syndrome | Simvastatin | 13.31 | 17105841 | |
MESH:D017119 | Porphyria Cutanea Tarda | Tetrachlorodibenzodioxin | 2.84 | 18163543 | |
MESH:D011230 | Precancerous Conditions | bromodichloromethane | 5.02 | 14668109 | |
MESH:D054198 | Precursor Cell Lymphoblastic Leukemia-Lymphoma | Dexamethasone | 3.07 | 21297632 | |
MESH:D011248 | Pregnancy Complications | bromodichloromethane | 5.36 | 12970577 17344021 14657523 | |
MESH:D011297 | Prenatal Exposure Delayed Effects | bisphenol A | 17.14 | 10548101 | |
MESH:D011297 | Prenatal Exposure Delayed Effects | Diethylstilbestrol | 17.14 | 17184923 | |
MESH:D011297 | Prenatal Exposure Delayed Effects | Tetrachlorodibenzodioxin | 17.14 | 11896295 11118676 11399792 11222880 | |
MESH:D011297 | Prenatal Exposure Delayed Effects | vinclozolin | 17.14 | 18042343 18220299 19015723 | |
MESH:D011469 | Prostatic Diseases | vinclozolin | 4.18 | 18220299 | |
MESH:D019048 | Prostatic Intraepithelial Neoplasia | bisphenol A | 8.28 | 20887781 | |
MESH:D019048 | Prostatic Intraepithelial Neoplasia | Estradiol | 8.28 | 20887781 | |
MESH:D011471 | Prostatic Neoplasms | arsenic trioxide | 2.52 | 19131511 | |
MESH:D011471 | Prostatic Neoplasms | bisphenol A | 2.52 | 16740699 | |
MESH:D011471 | Prostatic Neoplasms | Copper | 2.52 | 17079463 17308104 | |
MESH:D011471 | Prostatic Neoplasms | Diethylstilbestrol | 2.52 | 15046698 15846301 17136230 | |
MESH:D011471 | Prostatic Neoplasms | Estradiol | 2.52 | 16740699 | |
MESH:D011471 | Prostatic Neoplasms | Flutamide | 2.52 | 3169114 | |
MESH:D011471 | Prostatic Neoplasms | Raloxifene | 2.52 | 16220300 15731164 16536755 | |
MESH:D011471 | Prostatic Neoplasms | Tamoxifen | 2.52 | 15067354 | |
MESH:D011471 | Prostatic Neoplasms | Vitamin E | 2.52 | 15084515 | |
MESH:D011472 | Prostatitis | vinclozolin | 4.18 | 18629315 | |
MESH:D011537 | Pruritus | Ethinyl Estradiol | 7.52 | 16919318 15861022 | |
MESH:D011537 | Pruritus | Levonorgestrel | 7.52 | 15861022 | |
MESH:D011629 | Puberty, Precocious | astressin B | 11.06 | 20002962 | |
MESH:D011629 | Puberty, Precocious | bisphenol A | 11.06 | 10548101 | |
MESH:D011657 | Pulmonary Eosinophilia | Ascorbic Acid | 4.57 | 14606601 | |
MESH:D011693 | Purpura | Raloxifene | 4.79 | 15770314 | |
MESH:D012004 | Rectal Neoplasms | bromodichloromethane | 5.23 | 17535441 | |
MESH:D012021 | Reflex, Abnormal | Pentobarbital | 5.27 | 10930210 | |
MESH:D012128 | Respiratory Distress Syndrome, Adult | Dexamethasone | 3.33 | 18379247 11700416 | |
MESH:D012130 | Respiratory Hypersensitivity | Lipopolysaccharides | 3.20 | 10835634 | |
MESH:D012135 | Respiratory Sounds | Atrazine | 3.79 | 11874814 | |
MESH:D015619 | Respiratory System Abnormalities | Tetrachlorodibenzodioxin | 3.12 | 18990726 | |
MESH:D012162 | Retinal Degeneration | 4,4'-diaminodiphenylmethane | 2.79 | 3692021 | |
MESH:D012174 | Retinitis Pigmentosa | Ascorbic Acid | 3.04 | 16849425 | |
MESH:D012468 | Salivary Gland Neoplasms | Progesterone | 2.53 | 18045962 | |
MESH:D012512 | Sarcoma, Ewing's | arsenic trioxide | 3.25 | 16646077 | |
MESH:D012559 | Schizophrenia | Copper | 2.96 | 16842975 | |
MESH:D012640 | Seizures | Ethanol | 7.20 | 9754883 | |
MESH:D012640 | Seizures | Methomyl | 7.20 | 12660363 11218047 | |
MESH:D012640 | Seizures | Pentobarbital | 7.20 | 9754883 10087439 | |
MESH:D012871 | Skin Diseases | Ascorbic Acid | 4.31 | 18709164 | |
MESH:D012871 | Skin Diseases | Vitamin E | 4.31 | 18709164 | |
MESH:D012878 | Skin Neoplasms | Tetrachlorodibenzodioxin | 1.65 | 16192470 | |
MESH:D013088 | Spermatocele | Diethylstilbestrol | 15.72 | 16002989 16709447 | |
MESH:D013088 | Spermatocele | Ethinyl Estradiol | 15.72 | 16709447 | |
MESH:D013088 | Spermatocele | Tamoxifen | 15.72 | 16709447 | |
MESH:D013119 | Spinal Cord Injuries | Progesterone | 8.38 | 16503802 15862959 | |
MESH:D013119 | Spinal Cord Injuries | Tamoxifen | 8.38 | 19457130 | |
MESH:D013272 | Stomach Diseases | Dexamethasone | 3.58 | 15472012 | |
MESH:D013274 | Stomach Neoplasms | arsenic trioxide | 2.39 | 17007042 | |
MESH:D013274 | Stomach Neoplasms | Ethanol | 2.39 | 18456281 | |
MESH:D013276 | Stomach Ulcer | Ascorbic Acid | 8.38 | 18726076 | |
MESH:D013276 | Stomach Ulcer | Dexamethasone | 8.38 | 15138204 | |
MESH:D013276 | Stomach Ulcer | Ethanol | 8.38 | 17189318 16755016 9211565 17918041 9562338 11906479 | |
MESH:D020521 | Stroke | Ascorbic Acid | 10.95 | 16403987 16517955 | |
MESH:D020521 | Stroke | Raloxifene | 10.95 | 16837676 | |
MESH:D020521 | Stroke | Vitamin E | 10.95 | 16517955 | |
MESH:D019966 | Substance-Related Disorders | bisphenol A | 3.24 | 16684133 16045194 | |
MESH:D013375 | Substance Withdrawal Syndrome | Ethanol | 8.05 | 9754883 | |
MESH:D013375 | Substance Withdrawal Syndrome | Pentobarbital | 8.05 | 11529278 9754883 | |
MESH:D013576 | Syndactyly | methoxyacetic acid | 4.91 | 1761407 1761404 | |
MESH:D013733 | Testicular Diseases | methoxyacetic acid | 4.58 | 18486176 6499806 | |
MESH:D013921 | Thrombocytopenia | Lipopolysaccharides | 3.50 | 15821434 | |
MESH:D019851 | Thrombophilia | Ethinyl Estradiol | 8.79 | 11994571 | |
MESH:D019851 | Thrombophilia | ethinyl estradiol-desogestrel combination | 8.79 | 11994571 | |
MESH:D013927 | Thrombosis | Ethinyl Estradiol | 2.51 | 15669648 | |
MESH:D013959 | Thyroid Diseases | Tetrachlorodibenzodioxin | 9.96 | 12697716 | |
MESH:D013959 | Thyroid Diseases | Triclosan | 9.96 | 19910387 | |
MESH:D013964 | Thyroid Neoplasms | 4,4'-diaminodiphenylmethane | 5.19 | 6582329 1399818 3712494 6587162 7505956 | |
MESH:D013964 | Thyroid Neoplasms | arsenic trioxide | 5.19 | 19014326 | |
MESH:D013978 | Tibial Fractures | Estradiol | 11.17 | 19048282 | |
MESH:D013978 | Tibial Fractures | Raloxifene | 11.17 | 19048282 | |
MESH:D016171 | Torsades de Pointes | arsenic trioxide | 3.22 | 15213294 | |
MESH:D001749 | Urinary Bladder Neoplasms | 4,4'-diaminodiphenylmethane | 11.87 | 8074119 | |
MESH:D001749 | Urinary Bladder Neoplasms | arsenic trioxide | 11.87 | 11780464 20435036 12973940 12845720 | |
MESH:D001749 | Urinary Bladder Neoplasms | Diethylstilbestrol | 11.87 | 16452187 16712894 17306315 | |
MESH:D001749 | Urinary Bladder Neoplasms | Raloxifene | 11.87 | 17572228 | |
MESH:D001749 | Urinary Bladder Neoplasms | Tamoxifen | 11.87 | 16712894 17572228 8653321 | |
MESH:D014581 | Urticaria | Acetaminophen | 2.29 | 10982225 | |
MESH:D002583 | Uterine Cervical Neoplasms | Diethylstilbestrol | 3.37 | 16175088 | |
MESH:D014591 | Uterine Diseases | bisphenol A | 11.27 | 14652134 | |
MESH:D014591 | Uterine Diseases | Diethylstilbestrol | 11.27 | 14652134 | |
MESH:D014594 | Uterine Neoplasms | Diethylstilbestrol | 7.10 | 15809267 16690809 | |
MESH:D014594 | Uterine Neoplasms | Ethinyl Estradiol | 7.10 | 14692618 | |
MESH:D014605 | Uveitis | Dexamethasone | 4.05 | 1336536 | |
MESH:D014625 | Vaginal Neoplasms | Diethylstilbestrol | 3.70 | 16002989 16513791 | |
MESH:D054079 | Vascular Malformations | Tetrachlorodibenzodioxin | 3.83 | 12125929 | |
MESH:D054556 | Venous Thromboembolism | Raloxifene | 4.44 | 16837676 | |
MESH:D020246 | Venous Thrombosis | Ethinyl Estradiol | 14.00 | 14671159 15869587 | |
MESH:D020246 | Venous Thrombosis | ethinyl estradiol-desogestrel combination | 14.00 | 15869587 | |
MESH:D020246 | Venous Thrombosis | Levonorgestrel | 14.00 | 15869587 | |
MESH:D014846 | Vulvar Neoplasms | Raloxifene | 4.79 | 16343187 | |
MESH:D019282 | Wasting Syndrome | Tetrachlorodibenzodioxin | 3.48 | 15886252 | |
MESH:D014947 | Wounds and Injuries | Nitrofurazone | 4.78 | 18440737 18222664 |
Pathway ID | Pathway Name |
---|---|
KEGG:04912 | GnRH signaling pathway |
REACT:15314 | Hormone biosynthesis |
REACT:13 | Metabolism of amino acids and derivatives |
KEGG:04080 | Neuroactive ligand-receptor interaction |
REACT:14797 | Signaling by GPCR |