AutismKB 2.0

Annotation Detail for ABLIM1


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Basic Information Top
Gene Symbol:ABLIM1 ( ABLIM,DKFZp781D0148,FLJ14564,KIAA0059,LIMAB1,LIMATIN,MGC1224 )
Gene Full Name: actin binding LIM protein 1
Band: 10q25.3
Quick LinksEntrez ID:3983; OMIM: 602330; Uniprot ID:ABLM1_HUMAN; ENSEMBL ID: ENSG00000099204; HGNC ID: 78
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04360Axon guidance
Pathway IDPathway Name
Axon guidance
No data
Pathway IDPathway Name
P00009Axon guidance mediated by netrin
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in decreased expression of ABLIM1 mRNAdecreases expression 18648102
C006632 arsenic trioxide arsenic trioxide results in increased expression of ABLIM1 mRNAincreases expression 20458559
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in decreased expression of ABLIM1 mRNAdecreases expression 15336504
D002117 Calcitriol Calcitriol results in increased expression of ABLIM1 mRNAincreases expression 16002434
D004317 Doxorubicin ABLIM1 protein affects the susceptibility to Doxorubicinaffects response to substance 16217747
D004958 Estradiol Estradiol affects the expression of ABLIM1 mRNAaffects expression 14699072
D015735 Mifepristone Mifepristone results in increased expression of ABLIM1 mRNAincreases expression 17584828
D016685 Mitomycin ABLIM1 protein affects the susceptibility to Mitomycinaffects response to substance 16217747
D010672 Phenytoin Phenytoin results in decreased expression of ABLIM1 mRNAdecreases expression 15136057
C006253 pirinixic acid pirinixic acid results in increased expression of ABLIM1 mRNAincreases expression 18301758
17426115
C059514 resveratrol resveratrol results in increased expression of ABLIM1 mRNAincreases expression 12569576
D012402 Rotenone Rotenone results in decreased expression of ABLIM1 mRNAdecreases expression 19013527
D014212 Tretinoin Tretinoin results in decreased expression of ABLIM1 mRNAdecreases expression 16169686
D014747 Vinblastine ABLIM1 protein affects the susceptibility to Vinblastineaffects response to substance 16217747
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Phenytoin 4.5710563481 3425630 9677735 9118846 6195326 8986270
MESH:D058186 Acute Kidney Injury resveratrol 3.9016538975
MESH:D055371 Acute Lung Injury pirinixic acid 3.1718653653
MESH:D000230 Adenocarcinoma arsenic trioxide 7.2211798837 19825857
MESH:D000230 Adenocarcinoma Doxorubicin 7.2217418594
MESH:D000230 Adenocarcinoma Estradiol 7.2211473722
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 6.943712494
MESH:D000236 Adenoma resveratrol 6.9415688382
MESH:D018248 Adenoma, Liver Cell pirinixic acid 3.5616434500
MESH:D000419 Albuminuria Doxorubicin 4.6121441931
MESH:D000505 Alopecia Tretinoin 3.6615955085
MESH:D000544 Alzheimer Disease resveratrol 2.5816183991 16162502
MESH:D001169 Arthritis, Experimental resveratrol 7.6217115116
MESH:D001169 Arthritis, Experimental Tretinoin 7.6216412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.2716292516
MESH:D001249 Asthma Tretinoin 2.3616456186
MESH:D050197 Atherosclerosis Phenytoin 7.2415136057
MESH:D050197 Atherosclerosis resveratrol 7.2416873680 17967414
MESH:D001471 Barrett Esophagus Tretinoin 4.4716935849
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 5.121440618 11289319
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 15.6816206674
MESH:D001778 Blood Coagulation Disorders pirinixic acid 15.6819483382
MESH:D001778 Blood Coagulation Disorders Tretinoin 15.6816206674 16197459
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 4.8014601052
MESH:D002545 Brain Ischemia resveratrol 4.3717600658
MESH:D001932 Brain Neoplasms Doxorubicin 3.8617150277
MESH:D001943 Breast Neoplasms Calcitriol 2.3711237771
MESH:D001943 Breast Neoplasms Doxorubicin 2.3716115903 18382427 18628466 15994142 15692762 15136595 17983394 15939500 15668708 17426702 16096432 16935488 17369602 16322301 18234424 15634643 11325840 16826403 15993339 16595493 19526202 15567936 16264153 18695136
MESH:D001943 Breast Neoplasms Estradiol 2.3718497071 12948864 17018787 17261762 19861407 16675129 17289903 14630087
MESH:D001943 Breast Neoplasms resveratrol 2.3717651959 16393696 17534123
MESH:D001943 Breast Neoplasms Tretinoin 2.3716443354 16873071 16166294
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.6716813970
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.3911589617
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.5516111702
MESH:D002276 Carcinoid Tumor Doxorubicin 4.9116051944
MESH:D018236 Carcinoma, Embryonal Tretinoin 5.2616168501
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 11.523581430 7296757
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 11.5211135700 16217749 14691202 15073043 15553829
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 11.5218059187 16234567 16023760 17876044
MESH:D006528 Carcinoma, Hepatocellular Estradiol 11.5216924424
MESH:D006528 Carcinoma, Hepatocellular resveratrol 11.5216227395 19321006
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 11.521917145
MESH:D018827 Carcinoma, Lewis Lung resveratrol 4.6716675471
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.9719014326
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 11.037296757
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 11.0316201981 1485588
MESH:D002292 Carcinoma, Renal Cell Vinblastine 11.031485588
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.1712490120
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 10.9811237771
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 10.986189445
MESH:D002294 Carcinoma, Squamous Cell resveratrol 10.9816227395
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 10.9816051514 16096774
MESH:D009202 Cardiomyopathies Doxorubicin 3.5616242529 17974986 17519947 17924179 17308081 17382496 16455267 16612575 15476868 17007740 17131338 15792986 17329180 16651473 16952015 16109756 16364871 15505089 16278810 18627295 16731534 17351982 17928571 16269455 15811867
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.9617334414 16243910
MESH:D002318 Cardiovascular Diseases resveratrol 3.5115458977
MESH:D002386 Cataract Tretinoin 3.1217460283
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 6.787505956
MESH:D002471 Cell Transformation, Neoplastic Estradiol 6.7818566989
MESH:D002493 Central Nervous System Diseases Phenytoin 5.374080065
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.6716129372
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 7.989022650 19486331
MESH:D002779 Cholestasis pirinixic acid 7.9819176532
OMIM:601042 CHOREOATHETOSIS/SPASTICITY, EPISODIC Phenytoin 5.9511748493
MESH:D002822 Choriocarcinoma Tretinoin 5.2616461808
MESH:D002971 Cleft Lip Phenytoin 4.182227380
MESH:D002972 Cleft Palate Phenytoin 6.446862529 2227380 3877104 10789828 1687470 6856622
MESH:D002972 Cleft Palate Tretinoin 6.449407595
MESH:D003092 Colitis resveratrol 9.8716474422
MESH:D003092 Colitis Tretinoin 9.8717035595
MESH:D003103 Coloboma Phenytoin 5.219212184
MESH:D003110 Colonic Neoplasms resveratrol 2.4616338953
MESH:D015179 Colorectal Neoplasms arsenic trioxide 4.8920501625
MESH:D015179 Colorectal Neoplasms Doxorubicin 4.8918802399 18259882
MESH:D015179 Colorectal Neoplasms resveratrol 4.8916550006
MESH:D015179 Colorectal Neoplasms Vinblastine 4.8918802399
MESH:D000013 Congenital Abnormalities Phenytoin 4.7510627286
MESH:D003327 Coronary Disease resveratrol 3.7816507316
MESH:D023903 Coronary Restenosis arsenic trioxide 4.2512609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 4.0110525206
MESH:D019465 Craniofacial Abnormalities Phenytoin 4.018986270 9212184 19952982
MESH:D019465 Craniofacial Abnormalities Tretinoin 4.019125849 16925845 17551590 9142499 9664655 9211117 10589399 9224671 8800419 14991402
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 4.1515213294
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.8718759878 14531868 8156756 2524372 12868966 11298694 8970840 11906362
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.4518249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.553621924 2952479
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 3.8116873680
MESH:D003928 Diabetic Nephropathies Estradiol 9.1819279558
MESH:D003928 Diabetic Nephropathies resveratrol 9.1816286809
OMIM:607208 DRAVET SYNDROME Phenytoin 5.4611748493
MESH:D003875 Drug Eruptions Phenytoin 5.5715024534
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 4.0811289319 9022650 6482804 16192314 9653073 1440618 18648102 7440962 18692083 9328219 18289764 8291058 6679447
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 4.0817416283
MESH:D004362 Drug Toxicity Doxorubicin 3.7118602426
MESH:D004487 Edema pirinixic acid 7.0812083418
MESH:D004487 Edema resveratrol 7.088985016
MESH:D004489 Edema, Cardiac Tretinoin 4.5618230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 16.0015138306
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Phenytoin 16.0017654737
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 16.0017872969
MESH:D016889 Endometrial Neoplasms Doxorubicin 12.6917359293
MESH:D016889 Endometrial Neoplasms Estradiol 12.6918566989 11473722 19148513
MESH:D016889 Endometrial Neoplasms Tretinoin 12.6916569247
MESH:D004715 Endometriosis Mifepristone 4.4216134523
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 5.2518037988
MESH:D020345 Enterocolitis, Necrotizing resveratrol 4.9217923197
MESH:D004816 Epidermal Necrolysis, Toxic Phenytoin 5.2620235791
MESH:D004820 Epidermolysis Bullosa Phenytoin 6.331399206 6251365
MESH:D004828 Epilepsies, Partial Phenytoin 5.0111558140 17116037
MESH:D004827 Epilepsy Phenytoin 3.96821787 20417680 11434505
MESH:D017029 Epilepsy, Complex Partial Phenytoin 5.377750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenytoin 5.153659116
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 4.523581430
MESH:D004938 Esophageal Neoplasms arsenic trioxide 4.5212903497
MESH:D005124 Eye Abnormalities Tretinoin 3.629664655 16938888
MESH:D005234 Fatty Liver arsenic trioxide 7.9015073043
MESH:D005234 Fatty Liver pirinixic acid 7.9020131406 19236843
MESH:D005313 Fetal Death Phenytoin 5.1710627286
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 5.126705139
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 4.6719069698
MESH:D005355 Fibrosis Tretinoin 3.5817994277
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.3316904648
MESH:D005885 Gingival Hyperplasia Phenytoin 5.759029455
MESH:D019214 Gingival Overgrowth Phenytoin 6.3316390469 14659971
MESH:D005909 Glioblastoma Doxorubicin 7.3617150277
MESH:D005909 Glioblastoma Tretinoin 7.3617312396
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 4.107505956
MESH:D006258 Head and Neck Neoplasms Doxorubicin 7.9615692506
MESH:D006258 Head and Neck Neoplasms Tretinoin 7.9616096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 5.2616084493
MESH:D006330 Heart Defects, Congenital Tretinoin 2.9214991402 9664655
MESH:D006331 Heart Diseases Doxorubicin 3.5216330681 14766674 16707910 16244371 12587719 16144979 17888722 18674790 18006777 17875725 16879835 16495754 16244372
MESH:D006333 Heart Failure Doxorubicin 7.1617481944
MESH:D006333 Heart Failure pirinixic acid 7.1620558911
MESH:D006394 Hemangiosarcoma Doxorubicin 3.9515692506
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 3.586705139
MESH:D006529 Hepatomegaly pirinixic acid 3.0719176532 18467677 19772884 16221962
MESH:D006558 Herpes Genitalis Estradiol 5.1315709030
MESH:D006561 Herpes Simplex resveratrol 4.2616876885
MESH:D006689 Hodgkin Disease Doxorubicin 7.9617606976 18501091 15147373
MESH:D006689 Hodgkin Disease Vinblastine 7.9618180244 18501091
MESH:D019584 Hot Flashes Estradiol 3.8517088409
MESH:D006930 Hyperalgesia Tretinoin 3.2516870215
MESH:D006937 Hypercholesterolemia resveratrol 4.0617188708
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.6416778211
MESH:D006943 Hyperglycemia pirinixic acid 3.2320558911
MESH:D020138 Hyperhomocysteinemia Phenytoin 4.7210459572
MESH:D006949 Hyperlipidemias resveratrol 4.0916873680
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 4.0115034207
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 4.3517488730
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 4.7217600658
MESH:D007249 Inflammation resveratrol 2.8716366677
MESH:D007251 Influenza, Human resveratrol 4.6416624496
MESH:D007333 Insulin Resistance Estradiol 7.3116627594 16393666
MESH:D007333 Insulin Resistance pirinixic acid 7.3116306350
MESH:D007410 Intestinal Diseases Tretinoin 3.8417994277
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 5.128074119 9022650
MESH:D007569 Jaw Abnormalities Tretinoin 3.9515992940 17551590
MESH:D007674 Kidney Diseases Doxorubicin 6.3016775033 15699352 15369732
MESH:D007674 Kidney Diseases Estradiol 6.3015618244
MESH:D007676 Kidney Failure, Chronic Doxorubicin 4.2116707910
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 7.516582329
MESH:D007680 Kidney Neoplasms Estradiol 7.5115610895
MESH:D007938 Leukemia arsenic trioxide 6.4315070760
MESH:D007938 Leukemia Tretinoin 6.4317143497
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 5.2516085563
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.8512560223 17077332
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.3916972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.4714633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 9.6619077051
MESH:D007951 Leukemia, Myeloid Tretinoin 9.6616932348 16482212 19285840
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 3.9117050201 16467208 16968895 20471514 19850784
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 3.9117596541 19850784 16294345
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 12.9916112521 19642359 12712474 15213294 11468182 16966277 9834237 16891316 17107899 17649720 16330433 19075265 17712046 19225113 15748426 19035177 12679006 11161223 12018890 16823087 17217047 15622746 17869043 15336539 16331271
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 12.9916087638
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 12.9917217047 19075265 19225113 17361223 17301526 17649720 19029980 17506722 16935935 16788101 16766008 12679006 15748426 16823087 17368321 17294898 16331271 16891316 9834237 17339181 19642359 17107899 19035177 17712046 16140955
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.4216882451
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.349224671
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.2315034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 5.0116595196 16439617
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 5.0114659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 5.0115474484
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 5.0118397230 16248980
MESH:D008107 Liver Diseases Phenytoin 3.2314986274
MESH:D008113 Liver Neoplasms arsenic trioxide 10.9414682389
MESH:D008113 Liver Neoplasms Mitomycin 10.9415113037
MESH:D008113 Liver Neoplasms pirinixic acid 10.9420007298 15890375 16377806
MESH:D008113 Liver Neoplasms resveratrol 10.9419073162 19812893 19321006 20405173
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 10.113712494 598648 6587162 1399818
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 10.1120377131
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 10.1116842330 17085340
MESH:D008133 Long QT Syndrome arsenic trioxide 3.3915213294
MESH:D008175 Lung Neoplasms arsenic trioxide 2.6411798837 19825857
MESH:D008175 Lung Neoplasms Doxorubicin 2.646189445 17418594
MESH:D008223 Lymphoma Doxorubicin 3.5016098063
MESH:D016393 Lymphoma, B-Cell resveratrol 4.3617088997
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 9.0317654614
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 9.0314749477
MESH:D016399 Lymphoma, T-Cell Doxorubicin 4.6415621674
MESH:D015674 Mammary Neoplasms, Animal resveratrol 4.3315688416
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 10.2615458769
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 10.2611408345 16891317 17203775 11807958
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 10.268985016 11606380
MESH:D020149 Manganese Poisoning Estradiol 4.5819453300
MESH:D008527 Medulloblastoma Tretinoin 2.8017453147
MESH:D008545 Melanoma Doxorubicin 7.4616827129
MESH:D008545 Melanoma resveratrol 7.4617992120
MESH:D008545 Melanoma Tretinoin 7.4616752155
MESH:D008545 Melanoma Vinblastine 7.4615577320 16809738 18176117 16432458 16248763 17761969 12374674 15577323 18332650 18505091
MESH:D008591 Meningomyelocele Tretinoin 4.5016940565
MESH:D008607 Mental Retardation Phenytoin 3.689212184
MESH:D008654 Mesothelioma Doxorubicin 3.0817638057
MESH:D008659 Metabolic Diseases resveratrol 4.4317112576
MESH:D028361 Mitochondrial Diseases Doxorubicin 4.5515792986
MESH:D052016 Mucositis Doxorubicin 4.8717415656
MESH:D009101 Multiple Myeloma arsenic trioxide 7.5515949261 19417148 11468182 14977855 19549372
MESH:D009101 Multiple Myeloma resveratrol 7.5514749477 16267019 17049120 17164350 17935668 16490592
MESH:D009134 Muscular Atrophy, Spinal resveratrol 4.9517962980
MESH:D009135 Muscular Diseases pirinixic acid 3.5816239165
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.7718349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 7.4916105982 16882451
MESH:D009190 Myelodysplastic Syndromes Tretinoin 7.4917596541
MESH:D009203 Myocardial Infarction Doxorubicin 9.6315857846 19429709
MESH:D009203 Myocardial Infarction pirinixic acid 9.6319151258
MESH:D009203 Myocardial Infarction resveratrol 9.6317015251 16317513 17125593 17188708 16456233 16525036
MESH:D017202 Myocardial Ischemia resveratrol 4.0517125593 17015251
MESH:D015428 Myocardial Reperfusion Injury Estradiol 8.3916810080
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 8.3916411023
MESH:D009205 Myocarditis resveratrol 4.8417322642
MESH:D020191 Myoclonic Epilepsies, Progressive Phenytoin 5.6017484760
MESH:D009224 Myotonia Congenita Phenytoin 5.491896199
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 4.0216624393
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 5.913581430
MESH:D009362 Neoplasm Metastasis Doxorubicin 5.9118259882
MESH:D009369 Neoplasms pirinixic acid 4.9917405874
MESH:D009369 Neoplasms Tretinoin 4.9916946489 16594593
MESH:D009374 Neoplasms, Experimental resveratrol 4.078985016
MESH:D009389 Neovascularization, Pathologic Estradiol 3.8117289903
MESH:D009401 Nephrosis Doxorubicin 4.8416636307 16899518
MESH:D009404 Nephrotic Syndrome Doxorubicin 4.0515640375 16889571
MESH:D009410 Nerve Degeneration Rotenone 3.9218619942 15790535 17356569
MESH:D009421 Nervous System Malformations Estradiol 9.8911399458 16427766
MESH:D009421 Nervous System Malformations Tretinoin 9.899125849
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 17.676679447
MESH:D009436 Neural Tube Defects arsenic trioxide 17.6710525206
MESH:D009436 Neural Tube Defects Phenytoin 17.679118846
MESH:D009436 Neural Tube Defects Tretinoin 17.679142499
MESH:D009447 Neuroblastoma Doxorubicin 3.2915555623
MESH:D019636 Neurodegenerative Diseases resveratrol 3.8517652729
MESH:D020078 Neurogenic Inflammation resveratrol 4.4617929310
MESH:D009503 Neutropenia Vinblastine 4.6317378895
MESH:D009765 Obesity pirinixic acid 1.8220558911
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.476482804 4026338
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 5.123988306
MESH:D010018 Osteomalacia Phenytoin 5.4917016548
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 4.3117513867
MESH:D012516 Osteosarcoma Doxorubicin 4.1615930896
MESH:D010051 Ovarian Neoplasms arsenic trioxide 11.4619769630 16624393 12452020
MESH:D010051 Ovarian Neoplasms Estradiol 11.4619401270
MESH:D010051 Ovarian Neoplasms Mifepristone 11.4616525653
MESH:D010051 Ovarian Neoplasms Tretinoin 11.4616936753
MESH:D010146 Pain Phenytoin 7.3215215642
MESH:D010146 Pain Tretinoin 7.3216870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 8.8615580305
MESH:D010190 Pancreatic Neoplasms Mitomycin 8.8615113037
MESH:D010190 Pancreatic Neoplasms Tretinoin 8.8615976015
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.557296757
MESH:D010235 Paraganglioma arsenic trioxide 4.2219927285
MESH:D010300 Parkinson Disease Rotenone 2.9919114014 11445065 18191903 11535288 16412576 18619942 15451049 19232380 16140633
MESH:D020734 Parkinsonian Disorders Rotenone 4.1318197244 15927086 15795934 15574749
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.576228378
MESH:D003557 Phyllodes Tumor Doxorubicin 5.2517983394
MESH:D010997 Pleural Neoplasms Doxorubicin 5.2517638057
MESH:D017689 Polydactyly Phenytoin 5.099212184
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 4.2616679765
MESH:D011470 Prostatic Hyperplasia Calcitriol 4.8615572423
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.9420887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 1.8719131511
MESH:D011471 Prostatic Neoplasms Calcitriol 1.8718247401 12479363 15754350 16644109 16289102
MESH:D011471 Prostatic Neoplasms Doxorubicin 1.8715749863 16868541 16729912 15897917 16888761 18437689
MESH:D011471 Prostatic Neoplasms Estradiol 1.8716740699
MESH:D011471 Prostatic Neoplasms resveratrol 1.8716731767 17804756 15767336 17636462 17718901 17675339
MESH:D011507 Proteinuria Tretinoin 3.6616636307
MESH:D019310 Pseudolymphoma Phenytoin 5.648603615 1419762 12752131
MESH:D011625 Pterygium Tretinoin 4.8816723453
MESH:D051437 Renal Insufficiency Doxorubicin 4.2917922066
MESH:D051436 Renal Insufficiency, Chronic resveratrol 5.6816325855
MESH:D015427 Reperfusion Injury pirinixic acid 6.6519058328
MESH:D015427 Reperfusion Injury resveratrol 6.6515827377 16317513 16314181 17058453 17520802
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.413692021
MESH:D012208 Rhabdomyosarcoma Tretinoin 4.1616116481 16283617
MESH:D012509 Sarcoma Doxorubicin 4.0418313854 17203757 15625365 16767912 15675481 17710206
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 10.5016646077
MESH:D012512 Sarcoma, Ewing's Doxorubicin 10.5016326096 14601052
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.8717846226
MESH:D012640 Seizures Phenytoin 3.7715946322 3137016 3691417 19919933 9844417 10029267 16876388 11044598
MESH:D012878 Skin Neoplasms Doxorubicin 13.8315692506
MESH:D012878 Skin Neoplasms resveratrol 13.838985016 15837718
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 13.838532709
MESH:D012878 Skin Neoplasms Tretinoin 13.8316467112
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 4.6416767912 17203757 15625365
MESH:D013262 Stevens-Johnson Syndrome Phenytoin 5.2320235791
MESH:D013274 Stomach Neoplasms arsenic trioxide 2.4717007042
MESH:D013274 Stomach Neoplasms Tretinoin 2.4717261132
OMIM:601367 STROKE, ISCHEMIC resveratrol 4.5316321402
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 17.471399818 6587162 6582329 7505956 3712494
MESH:D013964 Thyroid Neoplasms arsenic trioxide 17.4719014326
MESH:D013964 Thyroid Neoplasms Doxorubicin 17.4717909728 16010429
MESH:D013964 Thyroid Neoplasms Tretinoin 17.4717045167 16026305
MESH:D013978 Tibial Fractures Estradiol 4.7819048282
MESH:D014062 Tongue Neoplasms resveratrol 10.0816227395
MESH:D014062 Tongue Neoplasms Tretinoin 10.0816051514
MESH:D016171 Torsades de Pointes arsenic trioxide 4.0415213294
MESH:D014376 Tuberculosis Tretinoin 3.2616040207
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 8.498074119
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 8.4911780464 20435036 12845720 12973940
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 8.4917653716
MESH:D002583 Uterine Cervical Neoplasms resveratrol 9.7017473185
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 9.7016129372
MESH:D014594 Uterine Neoplasms resveratrol 4.2017044934
MESH:D014604 Uveal Neoplasms Tretinoin 4.7116752155
MESH:D014625 Vaginal Neoplasms Vinblastine 5.1215577323
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 10.5817678736 16364871 17638931 17334414
MESH:D018487 Ventricular Dysfunction, Left resveratrol 10.5817488730
MESH:D014820 Vitiligo Tretinoin 4.1216761959
MESH:D009396 Wilms Tumor Tretinoin 4.0216287080
Pathway ID Pathway Name
REACT:18266 Axon guidance
KEGG:04360 Axon guidance
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA35023
    • No data
    Releated disease ID Related disease Name
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    Releated drug ID Related drug Name
    PA450379mercaptopurine
    PA450428methotrexate
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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