AutismKB 2.0

Annotation Detail for SNX19


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Basic Information Top
Gene Symbol:SNX19 ( CHET8,DKFZp667I205,KIAA0254 )
Gene Full Name: sorting nexin 19
Band: 11q24.3-q25
Quick LinksEntrez ID:399979; OMIM: NA; Uniprot ID:SNX19_HUMAN; ENSEMBL ID: ENSG00000120451; HGNC ID: 21532
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of SNX19 mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of SNX19 mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of SNX19 mRNAaffects expression 17562736
D018038 Sodium Selenite Sodium Selenite results in increased expression of SNX19 mRNAincreases expression 18175754
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000799 Angioedema Acetaminophen 4.5710982225
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 4.7816705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 4.7816705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 4.783084413
MESH:D002386 Cataract Acetaminophen 2.7910977129
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 3.036135515
MESH:D019457 Chromosome Breakage Sodium Selenite 5.3115894690
MESH:D003490 Cyanosis 2,4-dinitrotoluene 12.8318551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 12.8318551238
MESH:D003920 Diabetes Mellitus Sodium Selenite 4.1516285004
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 9.7721346803 18551238
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 9.7718551238 21346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 9.7717522070 10663392 19420014 14725611 2444490 16227642 15968718 16781746 15619225 10915739 16485898 18071297 12594235 11461765 19164858 19416960 11421492 11739529 17562736 18713872 10774834 16081117 12392966 12540782 19370779 17906064 19923254 14986274 16393943 11287661 12153990 19739265 19085960 11529661 11743745 14550746 12705907 16177239 16109766 12958197 11834606
MESH:D056486 Drug-Induced Liver Injury Sodium Selenite 9.7715131321
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.8219426721
MESH:D005756 Gastritis Acetaminophen 4.4016983495
MESH:D006930 Hyperalgesia Acetaminophen 3.0216870215
MESH:D007333 Insulin Resistance Sodium Selenite 3.5214714311
MESH:D007674 Kidney Diseases Acetaminophen 2.4012587719 15629191
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 8.5316705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 8.5316705839
MESH:D008107 Liver Diseases Acetaminophen 1.7011587558 16610002 12587719 12969438 16611625 19784758 19460945 19014921
MESH:D017114 Liver Failure, Acute Acetaminophen 3.6316871587 17185352
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 2.277678174
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 2.772876786 2876784 6135515
MESH:D016393 Lymphoma, B-Cell Sodium Selenite 4.5214737004
MESH:D008546 Melanoma, Experimental Acetaminophen 4.1319513568
MESH:D009336 Necrosis 2,4-dinitrotoluene 12.5418551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 12.5418551238 7678174
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.2118514411
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 10.2316049721 12819281
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 10.2316049721
MESH:D010146 Pain Acetaminophen 2.7316870215
MESH:D011471 Prostatic Neoplasms Sodium Selenite 3.3318760546
MESH:D012640 Seizures 2,4-dinitrotoluene 6.7418551238
MESH:D012640 Seizures 2,6-dinitrotoluene 6.7418551238
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 5.4316049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 5.4316049721
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 14.1910091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 14.1910091137
MESH:D014581 Urticaria Acetaminophen 3.4410982225
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA134904352
  • No data
    Releated disease ID Related disease Name
    PA443797Coronary Disease
    No data
    Drug Bank Top

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    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018